GO:0060662

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Name salivary gland cavitation
Categary Process
Go Slim No
Go Link GO:0060662
Unique Molecular Interactions 72
Total Molecular Interactions 97
Total Single Events 881
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for salivary gland cavitation. They are ordered first by their pain relevance and then by number of times they were reported for salivary gland cavitation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT140922 Btnl2 Negative_regulation of EDA 1 0.00 0.88 0.8
2 INT27526 Binding of Sdcbp and Eda 1 0.13 0 0.65
3 INT343838 EDA Positive_regulation of TLR4 1 0.11 0.87 0.51
4 INT297316 Negative_regulation of Rock2 Positive_regulation of Cdh1 1 0.01 1.92 0.43
5 INT310934 Positive_regulation of Tgm2 Positive_regulation of Binding of IGHE 1 0.14 1.33 0.34
6 INT343832 Positive_regulation of EDA Positive_regulation of TLR4 1 0.11 0.43 0.27
7 INT343864 EDA Positive_regulation of Gene_expression of TLR4 1 0.11 0.44 0.25
8 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19
9 INT310932 Binding of Tgm2 and Serpinb1a 1 0.04 0.87 0.17
10 INT266417 Binding of TGM2 and S100a11 1 0.01 0.86 0.16
11 INT316482 Il6 Positive_regulation of Cdh1 1 0.03 0.33 0.15
12 INT250910 Thbs2 Regulation of Tgm2 1 0.04 0.3 0.13
13 INT270464 Binding of Shh and Smo 1 0.07 1.3 0.08
14 INT290906 Shh Positive_regulation of Egfr 1 0.23 0 0.08
15 INT349914 Binding of Cdh1 and Jup 1 0.11 0.47 0.07
16 INT310933 Il6 Positive_regulation of Tgm2 1 0.00 0.55 0.07
17 INT298349 HES3 Positive_regulation of Shh 1 0.12 0.14 0.07
18 INT349916 Binding of Ctnnd1 and Cdh1 1 0.17 0.47 0.07
19 INT290905 Gene_expression of Shh Positive_regulation of Gene_expression of Angpt1 1 0.14 0 0.06
20 INT251373 Binding of Cdh2 and Cdh1 1 0.17 0 0.04
21 INT213563 Binding of Ctnnd2 and Shh 1 0.27 0.09 0.04
22 INT270459 Binding of Shh and Gli1 1 0.02 0.65 0.04
23 INT348526 Binding of TRAF2 and EDAR 1 0.15 0.52 0.03
24 INT352014 Shh Positive_regulation of Gene_expression of Pax1 1 0.29 0.07 0.03
25 INT311655 Shh Positive_regulation of Gene_expression of Fgf8 1 0.31 0.18 0.03
26 INT270462 Shh Positive_regulation of Ccnd1 1 0.10 0.6 0.03
27 INT213559 Binding of Egf and Shh 1 0.17 0.07 0.03
28 INT290910 Pkm2 Negative_regulation of Shh 1 0.07 0.06 0
29 INT251370 Cdh2 Regulation of Gene_expression of Cdh1 1 0.21 0.35 0
30 INT205963 GLI1 Positive_regulation of Negative_regulation of SHH 1 0.22 0.58 0
31 INT314850 Shh Regulation of Atoh7 1 0.45 0.22 0
32 INT290908 Regulation of Shh Positive_regulation of Ntn1 1 0.12 0 0
33 INT290911 Gene_expression of Shh Positive_regulation of Pkm2 1 0.07 0 0
34 INT261963 Binding of Cacna1a and Tgm2 1 0.08 1.19 0
35 INT290904 Shh Positive_regulation of Prkcg 1 0.26 0.06 0
36 INT290900 Prkcg Regulation of Shh 1 0.23 0 0
37 INT205960 Binding of PTCH1 and SHH 1 0.21 0.71 0
38 INT312318 Binding of Cdh1 and Regulation of Transcription of Prl 1 0.30 0.39 0
39 INT290944 Shh Positive_regulation of VEGFA 1 0.04 0.05 0
40 INT270461 Shh Regulation of Gene_expression of Ptch1 1 0.48 0.07 0
41 INT310042 Binding of Cdh1 and Lsr1 1 0.01 0.09 0
42 INT205959 Binding of SHH and SMOX 1 0.12 0.72 0
43 INT191816 Binding of ETFA and TGM2 1 0.01 0.66 0
44 INT312316 Gene_expression of Cdh1 Negative_regulation of Prl 1 0.29 0 0
45 INT270471 Shh Regulation of VEGFA 1 0.39 0.08 0
46 INT290898 Shh Positive_regulation of Nos2 1 0.46 0.05 0
47 INT300891 Binding of Atp9a and Tgm2 1 0.00 0.39 0
48 INT270466 Ptch1 Regulation of Gene_expression of Shh 1 0.48 0.07 0
49 INT270460 Shh Positive_regulation of Gene_expression of Angpt1 1 0.04 0.08 0
50 INT300892 Binding of Atp8a1 and Tgm2 1 0.01 0.68 0
51 INT251372 Cdh1 Regulation of Gene_expression of Cdh2 1 0.21 0.35 0
52 INT270470 Shh Regulation of Gene_expression of VEGFA 1 0.39 0.15 0
53 INT290907 Shh Positive_regulation of Ntn1 1 0.32 0.05 0
54 INT205977 Binding of SHH and Ptch1 1 0.31 0.71 0
55 INT270469 Shh Positive_regulation of VEGFA 1 0.29 0.12 0
56 INT310039 Binding of Cdh1 and Slc30a4 1 0.04 0.46 0
57 INT270468 Shh Positive_regulation of Gene_expression of VEGFA 1 0.44 0.08 0
58 INT235009 Binding of DSG1 and Cdh1 1 0.02 0.87 0
59 INT264737 Hes1 Regulation of Shh 1 0.19 0.13 0
60 INT312317 Cdh1 Regulation of Transcription of Prl 1 0.41 0.39 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for salivary gland cavitation. They are ordered first by their pain relevance and then by number of times they were reported in salivary gland cavitation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT4431 Negative_regulation of Eda 10 0.46 3.53 6.81
2 INT105960 Gene_expression of Cdh1 41 0.76 22.28 5.56
3 INT51411 Negative_regulation of EDAR 8 0.41 1.05 5.49
4 INT56404 Gene_expression of EDA 16 0.75 7.09 4.24
5 INT5460 Positive_regulation of EDAR 10 0.23 8.18 2.71
6 INT79281 Gene_expression of Tgm2 14 0.76 7.46 2.37
7 INT59287 Positive_regulation of Eda 5 0.40 1.25 2.36
8 INT74241 Positive_regulation of Gene_expression of EDA 3 0.49 4.93 2.24
9 INT169705 Negative_regulation of Gene_expression of Cdh1 10 0.57 8.8 2.1
10 INT43044 Gene_expression of Eda 3 0.75 0.69 2
11 INT144973 Gene_expression of Shh 9 0.77 4.32 1.96
12 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77
13 INT26393 Localization of Eda 4 0.60 0.18 1.63
14 INT49402 Positive_regulation of EDA 6 0.61 4.23 1.43
15 INT198840 Transcription of EDA 1 0.58 0.97 1.26
16 INT4430 Regulation of Eda 2 0.23 0.38 1.24
17 INT122103 Negative_regulation of Cdh1 5 0.49 2.05 1.18
18 INT54044 Negative_regulation of EDA 7 0.42 2.54 1.14
19 INT253191 Positive_regulation of Gene_expression of Shh 2 0.66 2.57 1.14
20 INT13655 Binding of Eda 4 0.36 0.97 1.1
21 INT169704 Regulation of Gene_expression of Cdh1 4 0.35 1.75 1.09
22 INT165530 Positive_regulation of Shh 4 0.69 1.21 1.05
23 INT28733 Regulation of EDAR 4 0.12 2.11 0.89
24 INT276620 Negative_regulation of Cdh1 7 0.57 6.48 0.86
25 INT56118 Gene_expression of EDAR 27 0.35 6.33 0.82
26 INT25540 Regulation of TGM2 3 0.28 0.33 0.73
27 INT235069 Localization of Cdh1 9 0.74 3.81 0.71
28 INT344781 Transcription of Tgm2 1 0.28 1.55 0.68
29 INT189877 Gene_expression of Cdh1 55 0.58 9.36 0.66
30 INT105959 Positive_regulation of Gene_expression of Cdh1 5 0.49 2.65 0.57
31 INT301995 Regulation of Cdh1 5 0.44 3.8 0.48
32 INT206484 Localization of Shh 2 0.75 1.14 0.46
33 INT232798 Positive_regulation of Gene_expression of Shh 7 0.70 1.49 0.44
34 INT172558 Positive_regulation of Cdh1 11 0.49 8.92 0.42
35 INT230099 Negative_regulation of TGM2 1 0.31 2.77 0.42
36 INT79282 Positive_regulation of Tgm2 5 0.67 5.15 0.39
37 INT208559 Negative_regulation of Gene_expression of Shh 8 0.43 1.58 0.38
38 INT344782 Positive_regulation of Transcription of Tgm2 1 0.24 0.67 0.36
39 INT163029 Positive_regulation of Localization of EDAR 1 0.39 0 0.34
40 INT158794 Binding of EDA 2 0.47 1.61 0.33
41 INT115501 Gene_expression of TGM2 8 0.64 4.56 0.28
42 INT79280 Positive_regulation of Gene_expression of Tgm2 1 0.19 1.79 0.27
43 INT232795 Positive_regulation of Shh 2 0.70 3.68 0.26
44 INT191823 Positive_regulation of TGM2 2 0.30 1.95 0.25
45 INT234858 Binding of Cdh1 11 0.47 4.58 0.22
46 INT215000 Transcription of Cdh1 4 0.40 1.17 0.22
47 INT183062 Gene_expression of SHH 12 0.65 5.28 0.21
48 INT134477 Negative_regulation of SHH 2 0.37 1.13 0.2
49 INT163030 Localization of EDAR 1 0.59 0 0.17
50 INT232799 Regulation of Gene_expression of Shh 3 0.27 1.04 0.16
51 INT253177 Negative_regulation of Gene_expression of Shh 2 0.55 0.63 0.16
52 INT253190 Localization of Shh 2 0.77 1.06 0.13
53 INT253183 Negative_regulation of Shh 8 0.55 2.13 0.12
54 INT250897 Negative_regulation of Tgm2 1 0.05 0.25 0.12
55 INT180027 Binding of Tgm2 6 0.35 4.06 0.11
56 INT49401 Regulation of EDA 1 0.23 0.07 0.11
57 INT49403 Positive_regulation of Regulation of EDA 1 0.40 0.07 0.11
58 INT296622 Positive_regulation of Gene_expression of Cdh1 3 0.52 2.24 0.09
59 INT296623 Positive_regulation of Cdh1 2 0.35 1.88 0.09
60 INT270442 Transcription of Shh 1 0.53 0.25 0.09
61 INT276619 Negative_regulation of Transcription of Cdh1 1 0.24 0.57 0.09
62 INT213515 Binding of Shh 8 0.37 1.92 0.08
63 INT270453 Regulation of Shh 1 0.27 0.83 0.08
64 INT227944 Binding of EDAR 5 0.25 2.88 0.07
65 INT251364 Negative_regulation of Gene_expression of Cdh1 4 0.32 1.02 0.07
66 INT205973 Binding of SHH 3 0.35 1.03 0.07
67 INT273457 Regulation of Gene_expression of Tgm2 2 0.60 0.88 0.07
68 INT256862 Regulation of Shh 1 0.25 0 0.07
69 INT349912 Negative_regulation of Negative_regulation of Cdh1 1 0.42 1.04 0.05
70 INT270445 Positive_regulation of Localization of Shh 1 0.44 0.13 0.05
71 INT180025 Regulation of Tgm2 1 0.20 1.59 0.05
72 INT189881 Binding of Cdh1 6 0.36 1.24 0.04
73 INT181793 Positive_regulation of SHH 3 0.67 2.59 0.04
74 INT208560 Negative_regulation of Shh 2 0.59 2.22 0.04
75 INT251361 Transcription of Cdh1 1 0.36 0 0.04
76 INT349906 Negative_regulation of Localization of Cdh1 1 0.42 0.37 0.04
77 INT284713 Positive_regulation of Gene_expression of TGM2 1 0.04 0.73 0.03
78 INT253187 Negative_regulation of Transcription of Shh 1 0.41 0.55 0.03
79 INT253181 Transcription of Shh 1 0.68 0.54 0.03
80 INT179299 Binding of TGM2 3 0.24 1.02 0
81 INT251359 Regulation of Cdh1 2 0.34 0.47 0
82 INT189878 Localization of Cdh1 2 0.56 0.34 0
83 INT251362 Regulation of Gene_expression of Cdh1 2 0.46 0.4 0
84 INT158793 Negative_regulation of Positive_regulation of EDA 1 0.38 0 0
85 INT305071 Positive_regulation of Negative_regulation of EDAR 1 0.20 0 0
86 INT189879 Positive_regulation of Binding of Cdh1 1 0.08 0.15 0
87 INT301987 Negative_regulation of Positive_regulation of Cdh1 1 0.07 1.28 0
88 INT312313 Protein_catabolism of Cdh1 1 0.75 0.21 0
89 INT349911 Regulation of Negative_regulation of Cdh1 1 0.44 0.23 0
90 INT270356 Positive_regulation of Positive_regulation of EDAR 1 0.01 1.56 0
91 INT179298 Localization of TGM2 1 0.40 0.05 0
92 INT290918 Negative_regulation of Positive_regulation of Shh 1 0.41 0.25 0
93 INT324055 Regulation of Transcription of Cdh1 1 0.09 0.49 0
94 INT158795 Negative_regulation of Gene_expression of EDA 1 0.37 0 0
95 INT189883 Negative_regulation of Localization of Cdh1 1 0.07 0.06 0
96 INT256367 Localization of EDA 1 0.13 0 0
97 INT230972 Positive_regulation of Gene_expression of SHH 1 0.18 0.07 0
98 INT296611 Positive_regulation of Negative_regulation of Cdh1 1 0.11 0.78 0
99 INT310014 Phosphorylation of Cdh1 1 0.16 0.24 0
100 INT290929 Binding of Shh 1 0.31 0.1 0
101 INT301989 Positive_regulation of Binding of Cdh1 1 0.08 0.42 0
102 INT290927 Regulation of Positive_regulation of Shh 1 0.23 0 0
103 INT349904 Regulation of Localization of Cdh1 1 0.44 0.05 0
104 INT270449 Negative_regulation of Positive_regulation of Shh 1 0.43 0.24 0
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