GO:0060674

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Name placenta blood vessel development
Categary Process
Go Slim No
Go Link GO:0060674
Unique Molecular Interactions 87
Total Molecular Interactions 105
Total Single Events 682
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for placenta blood vessel development. They are ordered first by their pain relevance and then by number of times they were reported for placenta blood vessel development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT346217 Braf Positive_regulation of Phosphorylation of Map2k1 1 0.22 3.23 1.72
2 INT133616 Map2k1 Regulation of Fadd 1 0.04 0.29 0.97
3 INT133614 Map2k1 Regulation of Daxx 1 0.02 0.29 0.97
4 INT133615 Regulation of Map2k1 Regulation of Fadd 1 0.04 0.29 0.97
5 INT135446 Map2k1 Positive_regulation of Mapk3 1 0.54 0.25 0.91
6 INT184114 Tlr4 Positive_regulation of Socs3 2 0.65 1.14 0.83
7 INT134476 Cdk5 Regulation of Map2k1 1 0.69 0.88 0.71
8 INT124477 MAP2K1 Positive_regulation of Positive_regulation of MAPK1 1 0.12 1.35 0.65
9 INT254199 Il10 Positive_regulation of Gene_expression of Socs3 2 0.06 0.75 0.63
10 INT184105 Il6 Positive_regulation of Socs3 2 0.42 1.34 0.48
11 INT184094 Gene_expression of Socs3 Negative_regulation of Positive_regulation of Il6 1 0.12 1.49 0.48
12 INT264136 IFNA1 Positive_regulation of Socs3 1 0.01 0.38 0.46
13 INT290671 Binding of Socs3 and Stat3 2 0.23 1.59 0.45
14 INT184124 Socs3 Regulation of Il6 1 0.13 1.4 0.43
15 INT346222 Positive_regulation of Braf Positive_regulation of Map2k1 1 0.15 0.67 0.39
16 INT234608 Socs3 Negative_regulation of SOAT1 1 0.01 0.54 0.39
17 INT234607 Socs3 Negative_regulation of JAK1 1 0.01 0.54 0.39
18 INT184128 Socs3 Negative_regulation of Il6 1 0.12 1.14 0.36
19 INT184095 Il10 Positive_regulation of Socs3 1 0.21 0.49 0.34
20 INT184082 Binding of Socs3 and Il6 1 0.11 0.49 0.33
21 INT124475 MAP2K1 Positive_regulation of Positive_regulation of CPOX 1 0.04 0.68 0.33
22 INT126942 Binding of PKD2 and ZACN 1 0.00 1.38 0.28
23 INT315200 Negative_regulation of Binding of Socs3 and Stat3 1 0.26 1.18 0.27
24 INT316491 Socs3 Positive_regulation of Il11ra1 1 0.45 0.92 0.22
25 INT346224 Braf Negative_regulation of Phosphorylation of Map2k1 1 0.14 0.62 0.22
26 INT254687 Positive_regulation of Map2k1 Positive_regulation of Gene_expression of Mmp13 1 0.06 0.2 0.2
27 INT126944 Binding of PKD2 and Pkd1 2 0.08 2.09 0.19
28 INT254683 Positive_regulation of Map2k1 Positive_regulation of Gene_expression of Plaur 1 0.01 0.07 0.18
29 INT254698 Gopc Positive_regulation of Positive_regulation of Map2k1 1 0.06 0.07 0.18
30 INT184103 Binding of Socs3 and Il11ra1 1 0.12 0 0.17
31 INT304537 Map2k1 Positive_regulation of PRKG1 1 0.01 0.66 0.16
32 INT304503 Map2k1 Positive_regulation of Nos1 1 0.07 0.66 0.16
33 INT250778 Binding of Socs3 and Atl1 1 0.01 0.6 0.14
34 INT184104 Binding of Socs3 and Gopc 1 0.10 0 0.14
35 INT304499 Map2k1 Positive_regulation of Mapk1 1 0.12 0.8 0.1
36 INT188357 Csf2 Positive_regulation of Socs3 1 0.36 0.15 0.1
37 INT179869 COL1A1 Positive_regulation of SOCS3 1 0.04 0.99 0.1
38 INT179871 IK Positive_regulation of SOCS3 1 0.01 1 0.1
39 INT224531 Positive_regulation of Map2k1 Positive_regulation of Positive_regulation of Ankh 1 0.07 0.54 0.09
40 INT273373 SOCS3 Regulation of Phosphorylation of STAT3 1 0.42 0.06 0.08
41 INT131130 Binding of PKD1 and Krt16 1 0.01 1 0.08
42 INT184119 Socs3 Negative_regulation of Csf3 1 0.21 0.64 0.08
43 INT273369 SOCS3 Negative_regulation of JAK1 1 0.03 0 0.07
44 INT273363 SOCS3 Regulation of Protein_catabolism of SOCS1 1 0.02 0 0.07
45 INT273364 SOCS3 Regulation of SOCS1 1 0.02 0 0.07
46 INT286592 Binding of PKD1 and P1Ehs1 1 0.00 0.16 0.06
47 INT316492 Stat3 Positive_regulation of Socs3 1 0.46 0.19 0.06
48 INT286591 Binding of PKD1 and Id2 1 0.07 0.17 0.06
49 INT238218 STAT3 Positive_regulation of Gene_expression of Socs3 1 0.14 0 0.05
50 INT279889 Il6 Regulation of Socs3 1 0.21 0.17 0.05
51 INT184123 Socs3 Positive_regulation of Protein_catabolism of Insr 1 0.03 0.41 0.05
52 INT194699 MAP2K1 Positive_regulation of MAPK8 1 0.05 0 0.04
53 INT194703 MAP2K1 Positive_regulation of MAP2K6 1 0.21 0 0.04
54 INT194677 Binding of GADD45A and MAP2K1 1 0.27 0 0.04
55 INT194719 MAP2K1 Positive_regulation of MAPK1 1 0.27 0 0.04
56 INT276949 Hspd1 Positive_regulation of Gene_expression of Socs3 1 0.15 0.71 0.04
57 INT194701 MAP2K1 Positive_regulation of MAP2K4 1 0.21 0 0.04
58 INT194732 MAP2K1 Positive_regulation of Gene_expression of MAPK1 1 0.27 0 0.04
59 INT276967 Hspd1 Regulation of Gene_expression of Socs3 1 0.14 0.71 0.04
60 INT194691 MAP2K1 Positive_regulation of MAP2K3 1 0.23 0 0.04
61 INT295479 PRKCA Positive_regulation of MAP2K1 1 0.14 0.35 0.03
62 INT269502 Lta Negative_regulation of Map2k1 1 0.17 0.48 0.03
63 INT295474 IRF6 Positive_regulation of MAP2K1 1 0.18 0.41 0.03
64 INT254689 Gene_expression of Map2k2 Positive_regulation of Map2k1 1 0.30 0.4 0
65 INT245158 AD5 Regulation of PKD1 1 0.00 0.44 0
66 INT254707 Positive_regulation of Map2k1 Regulation of Gene_expression of BAK1 1 0.05 0.67 0
67 INT254692 Positive_regulation of Map2k1 Regulation of Gene_expression of Mdk 1 0.05 0.42 0
68 INT261883 PKD2 Positive_regulation of Localization of Ca2 1 0.02 0.67 0
69 INT254693 Gene_expression of Map2k1 Regulation of Map2k2 1 0.29 0.78 0
70 INT254686 Gene_expression of Map2k1 Regulation of Gene_expression of Mdk 1 0.08 0.42 0
71 INT286501 Binding of PKD1 and LILRB1 1 0.01 1.07 0
72 INT254703 Map2k1 Positive_regulation of Phosphorylation of MAPK1 1 0.10 0.91 0
73 INT254696 Map2k2 Regulation of Map2k1 1 0.18 0.78 0
74 INT254706 Positive_regulation of Map2k1 Positive_regulation of Phosphorylation of MAPK3 1 0.07 0.91 0
75 INT254704 Positive_regulation of Map2k1 Positive_regulation of Phosphorylation of MAPK1 1 0.10 1.43 0
76 INT254702 Map2k1 Positive_regulation of Phosphorylation of MAPK3 1 0.07 0.91 0
77 INT254684 Map2k2 Positive_regulation of Map2k1 1 0.45 0.4 0
78 INT336606 Binding of Mapk8 and Map2k1 1 0.09 0.72 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for placenta blood vessel development. They are ordered first by their pain relevance and then by number of times they were reported in placenta blood vessel development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT142464 Gene_expression of Socs3 58 0.77 52.04 15.34
2 INT142462 Positive_regulation of Gene_expression of Socs3 23 0.68 23.27 8.27
3 INT135443 Phosphorylation of Map2k1 11 0.80 2.44 8.01
4 INT171367 Phosphorylation of Map2k1 31 0.58 32.87 8
5 INT135441 Positive_regulation of Map2k1 15 0.67 6.6 7.87
6 INT93137 Negative_regulation of Map2k1 17 0.42 4.51 6.49
7 INT42378 Positive_regulation of Socs3 21 0.67 15.81 5.71
8 INT135440 Positive_regulation of Phosphorylation of Map2k1 5 0.49 1.32 5.22
9 INT106065 Negative_regulation of MAP2K1 27 0.57 12.69 3.97
10 INT134470 Positive_regulation of Map2k1 74 0.49 46.07 3.02
11 INT184005 Negative_regulation of Gene_expression of Socs3 6 0.48 8.76 2.74
12 INT142465 Negative_regulation of Socs3 8 0.48 8.31 2.62
13 INT127756 Negative_regulation of Map2k1 10 0.41 6.69 2.04
14 INT135444 Regulation of Map2k1 4 0.44 1.15 1.77
15 INT184032 Regulation of Socs3 6 0.37 4.08 1.48
16 INT104121 Positive_regulation of MAP2K1 8 0.61 4.84 1.41
17 INT175525 Positive_regulation of Phosphorylation of Map2k1 8 0.33 7.02 1.37
18 INT71782 Gene_expression of MAP2K1 7 0.68 3.17 1.37
19 INT184056 Regulation of Gene_expression of Socs3 4 0.45 4.24 1.22
20 INT179884 Gene_expression of SOCS3 10 0.67 16.57 1.14
21 INT184020 Localization of Socs3 3 0.75 4.05 1.06
22 INT152404 Regulation of PKD1 2 0.45 2.02 1.04
23 INT138287 Gene_expression of Map2k1 69 0.65 46.14 1.02
24 INT184026 Binding of Socs3 7 0.42 1.93 0.81
25 INT71778 Positive_regulation of Gene_expression of MAP2K1 2 0.36 0.37 0.81
26 INT211909 Regulation of Positive_regulation of Map2k1 1 0.21 0.47 0.76
27 INT129174 Gene_expression of PKD1 24 0.67 14.91 0.74
28 INT137850 Gene_expression of PKD2 9 0.65 6.68 0.63
29 INT104120 Positive_regulation of Positive_regulation of MAP2K1 1 0.49 0 0.54
30 INT184065 Phosphorylation of Socs3 2 0.81 2.67 0.53
31 INT236915 Binding of Map2k1 2 0.15 1.51 0.49
32 INT234580 Regulation of Positive_regulation of Socs3 1 0.26 0.54 0.46
33 INT179887 Positive_regulation of SOCS3 10 0.50 13.06 0.45
34 INT138282 Positive_regulation of Gene_expression of Map2k1 13 0.49 7.46 0.39
35 INT304528 Gene_expression of Map2k1 3 0.58 1.76 0.37
36 INT304526 Binding of Map2k1 1 0.11 0.6 0.32
37 INT240205 Regulation of MAP2K1 3 0.26 0.44 0.28
38 INT175506 Regulation of Positive_regulation of Map2k1 2 0.32 1.58 0.23
39 INT226426 Negative_regulation of SOCS3 2 0.15 10.24 0.22
40 INT304519 Positive_regulation of Gene_expression of Map2k1 1 0.15 0.41 0.22
41 INT234581 Transcription of Socs3 2 0.51 0.22 0.15
42 INT199521 Protein_catabolism of PKD1 2 0.96 0.39 0.15
43 INT254671 Regulation of Map2k1 5 0.43 1.83 0.14
44 INT265533 Negative_regulation of Phosphorylation of Map2k1 1 0.41 0 0.14
45 INT175527 Localization of Map2k1 4 0.31 2.41 0.13
46 INT254673 Positive_regulation of Positive_regulation of Map2k1 3 0.35 1.65 0.11
47 INT273407 Transcription of SOCS3 1 0.62 0.17 0.11
48 INT184044 Positive_regulation of Protein_catabolism of Socs3 2 0.38 0.47 0.1
49 INT184010 Protein_catabolism of Socs3 2 0.54 0.46 0.1
50 INT179890 Localization of SOCS3 1 0.54 1.02 0.1
51 INT315199 Regulation of Phosphorylation of Socs3 1 0.45 1.22 0.09
52 INT352530 Positive_regulation of Positive_regulation of SOCS3 1 0.15 1.77 0.08
53 INT273403 Positive_regulation of Transcription of SOCS3 1 0.40 0.06 0.08
54 INT215418 Positive_regulation of Phosphorylation of MAP2K1 1 0.03 0.51 0.08
55 INT215420 Phosphorylation of MAP2K1 1 0.05 0.51 0.08
56 INT140267 Negative_regulation of Positive_regulation of Socs3 1 0.31 0.53 0.07
57 INT273397 Binding of SOCS3 1 0.42 0 0.07
58 INT273405 Negative_regulation of Binding of SOCS3 1 0.37 0 0.07
59 INT286583 Localization of PKD2 1 0.35 0.17 0.06
60 INT211006 Binding of PKD1 6 0.22 2.69 0.05
61 INT261879 Binding of PKD2 3 0.13 2.59 0.05
62 INT300107 Positive_regulation of Gene_expression of SOCS3 1 0.15 3.58 0.05
63 INT281764 Negative_regulation of Gene_expression of Map2k1 1 0.18 1.11 0.04
64 INT300092 Regulation of SOCS3 1 0.08 3.03 0.03
65 INT175892 Negative_regulation of PKD1 2 0.42 1.03 0
66 INT241245 Negative_regulation of PKD2 2 0.42 2.35 0
67 INT329571 Binding of MAP2K1 2 0.11 0.4 0
68 INT332349 Positive_regulation of Regulation of Socs3 1 0.42 0.19 0
69 INT281758 Positive_regulation of Protein_catabolism of Map2k1 1 0.29 0.13 0
70 INT232493 Negative_regulation of Positive_regulation of PKD2 1 0.23 0.61 0
71 INT175898 Positive_regulation of PKD1 1 0.50 1.24 0
72 INT261880 Negative_regulation of Binding of PKD1 1 0.16 0.6 0
73 INT281756 Protein_catabolism of Map2k1 1 0.42 0.13 0
74 INT261878 Negative_regulation of Binding of PKD2 1 0.14 0.6 0
75 INT175533 Regulation of Gene_expression of Map2k1 1 0.20 1.55 0
76 INT232491 Positive_regulation of PKD2 1 0.27 0.56 0
77 INT175896 Transcription of PKD1 1 0.53 1.22 0
78 INT175890 Negative_regulation of Gene_expression of PKD1 1 0.42 0.11 0
79 INT300103 Positive_regulation of Negative_regulation of SOCS3 1 0.15 1.75 0
80 INT214908 Positive_regulation of Gene_expression of PKD1 1 0.35 0.86 0
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