GO:0060676

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Name ureteric bud formation
Categary Process
Go Slim No
Go Link GO:0060676
Unique Molecular Interactions 109
Total Molecular Interactions 151
Total Single Events 714
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for ureteric bud formation. They are ordered first by their pain relevance and then by number of times they were reported for ureteric bud formation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT180785 Gdnf Positive_regulation of Calca 1 0.23 1.96 8.04
2 INT180774 Gdnf Positive_regulation of Trpv1 1 0.33 2.43 4.37
3 INT122776 Gdnf Positive_regulation of Gene_expression of Trpv1 2 0.67 2.13 3.06
4 INT103330 Ngf Positive_regulation of Gdnf 2 0.28 1.27 2.45
5 INT122775 Gdnf Regulation of Gene_expression of Trpv1 4 0.59 2.72 2.42
6 INT115042 Gdnf Regulation of Calca 1 0.53 0.25 2.03
7 INT180812 Gdnf Positive_regulation of Gene_expression of Sorbs1 1 0.02 0.83 1.61
8 INT180811 Gdnf Positive_regulation of Regulation of Sorbs1 1 0.01 0.83 1.61
9 INT180791 Negative_regulation of Gdnf Regulation of Calca 1 0.17 0 1.47
10 INT180790 Gdnf Regulation of Localization of Trpv1 1 0.15 1.21 1.43
11 INT83197 Binding of Ntrk1 and Gdnf 1 0.01 1.05 1.36
12 INT180802 Gdnf Positive_regulation of Sorbs1 1 0.02 0.98 1.34
13 INT180764 Calca Regulation of Positive_regulation of Gdnf 1 0.21 0 1.32
14 INT242605 Gdnf Positive_regulation of Trpv1 1 0.26 0.17 1.3
15 INT148435 Binding of Bdnf and Gdnf 2 0.35 1.9 1.17
16 INT180814 Binding of Ret and Gdnf 1 0.01 1.31 1.17
17 INT242625 Gdnf Positive_regulation of Pax3 1 0.01 0.34 1.15
18 INT142413 Oprm1 Positive_regulation of Gdnf 1 0.19 0.29 1.09
19 INT133072 GATA3 Positive_regulation of Transcription of OPRM1 1 0.35 0 1.04
20 INT180770 Gdnf Positive_regulation of Zbtb38 1 0.00 0.27 0.99
21 INT147504 Binding of Ncam1 and Gdnf 1 0.31 0.87 0.98
22 INT180780 Ngf Regulation of Gdnf 1 0.22 0.28 0.96
23 INT180803 Sorbs1 Regulation of Gdnf 1 0.01 0.28 0.95
24 INT133071 STAT6 Positive_regulation of Gene_expression of GATA3 1 0.55 0 0.95
25 INT180787 Calca Regulation of Gdnf 1 0.18 0.28 0.95
26 INT147505 Binding of Ret and Gdnf 1 0.27 0.81 0.92
27 INT242621 Gdnf Positive_regulation of Gene_expression of Scn11a 1 0.05 0.12 0.88
28 INT103331 Ngf Positive_regulation of Gdnf 1 0.01 0.57 0.8
29 INT103334 Gdnf Regulation of Gene_expression of TRPV1 1 0.02 0.53 0.77
30 INT103333 Gdnf Regulation of TRPV1 1 0.02 0.53 0.77
31 INT180773 Calca Regulation of Binding of Gdnf 1 0.18 0.15 0.72
32 INT180783 Binding of Gdnf and Man2a2 1 0.00 0.52 0.71
33 INT180775 Binding of Gdnf and Gfra1 1 0.06 0.52 0.71
34 INT102121 Gdnf Regulation of Gene_expression of Cnr1 1 0.45 0.42 0.71
35 INT144367 Gdnf Negative_regulation of Positive_regulation of Th 1 0.11 0.77 0.7
36 INT122777 Gdnf Negative_regulation of Gene_expression of Trpv1 1 0.36 0.8 0.62
37 INT122774 Gdnf Negative_regulation of Positive_regulation of Trpv1 1 0.32 0.78 0.61
38 INT242584 Gdnf Regulation of Gene_expression of Qrfp 1 0.00 0.09 0.58
39 INT91267 Gdnf Negative_regulation of Gdnf 1 0.05 0.81 0.58
40 INT242598 Binding of Gdnf and Gfra2 4 0.16 0.38 0.51
41 INT242614 Binding of Gdnf and Gfra1 1 0.03 0 0.51
42 INT356279 Gdnf Regulation of Positive_regulation of Mapk1 1 0.03 0.76 0.5
43 INT98117 Gdnf Regulation of SCN11A 1 0.05 0.39 0.5
44 INT242597 Gene_expression of Gdnf Negative_regulation of Trpv1 1 0.27 0.08 0.5
45 INT98116 Gdnf Regulation of SCN10A 1 0.03 0.39 0.5
46 INT242638 Binding of BDNF and Gdnf 1 0.29 0 0.49
47 INT242600 Binding of Gdnf and Gopc 1 0.06 0 0.49
48 INT165582 Binding of Bdnf and Gdnf 1 0.36 0.47 0.49
49 INT242604 Gdnf Regulation of Gene_expression of Trpv1 1 0.17 0.36 0.48
50 INT98119 Gdnf Regulation of SCN10A 1 0.01 0.34 0.45
51 INT98118 Gdnf Regulation of SCN11A 1 0.01 0.34 0.45
52 INT104459 Gdnf Regulation of Ngf 1 0.26 0.56 0.45
53 INT127074 Gdnf Regulation of Gene_expression of Jun 1 0.10 0.28 0.43
54 INT127072 Gdnf Regulation of Gene_expression of Fos 1 0.38 0.28 0.43
55 INT127077 Gdnf Positive_regulation of Gene_expression of IER3 1 0.02 0.26 0.42
56 INT127079 Gene_expression of Gdnf Positive_regulation of Gene_expression of IER3 1 0.02 0.26 0.42
57 INT237454 Binding of STAR and GREM1 1 0.00 0.44 0.4
58 INT148436 Binding of Gdnf and Ngf 1 0.35 1.14 0.4
59 INT78627 Gdnf Negative_regulation of Negative_regulation of P2rx3 1 0.00 0.42 0.38
60 INT140869 Binding of Gdnf and Trib3 1 0.04 0.15 0.37
61 INT85909 Binding of Oprm1 and GREM1 1 0.00 0 0.32
62 INT300752 GATA3 Regulation of Hand2 1 0.01 0.06 0.3
63 INT356278 Gdnf Positive_regulation of Mapk1 1 0.05 0.17 0.3
64 INT356282 Gdnf Positive_regulation of Trib3 1 0.00 0.17 0.3
65 INT180788 Gdnf Regulation of Trpv1 1 0.13 0.2 0.28
66 INT317773 Positive_regulation of GATA3 Positive_regulation of HDAC1 1 0.23 0.69 0.25
67 INT317775 GATA3 Positive_regulation of HDAC1 1 0.23 0.69 0.25
68 INT26185 Positive_regulation of Binding of GREM1 and Cyth2 1 0.00 0 0.22
69 INT26186 Binding of GREM1 and Cyth2 1 0.00 0 0.22
70 INT277434 Cd5 Regulation of Gdnf 1 0.01 0 0.21
71 INT194829 Gata3 Positive_regulation of IL13 1 0.01 0.12 0.15
72 INT194835 Gata3 Positive_regulation of IL5 1 0.01 0.12 0.15
73 INT194833 Binding of IL5 and Gata3 1 0.01 0.12 0.15
74 INT194827 Binding of IL13 and Gata3 1 0.01 0.12 0.15
75 INT326385 Mtdh Regulation of Gdnf 1 0.00 0.41 0.14
76 INT193551 Mtpn Positive_regulation of Gene_expression of Gdnf 1 0.02 0.34 0.13
77 INT193552 Gdnf Positive_regulation of Gene_expression of Mtpn 1 0.02 0.34 0.13
78 INT277433 Wibg Positive_regulation of Gdnf 1 0.01 0.6 0.13
79 INT338428 Il4 Positive_regulation of Gata3 1 0.06 0.75 0.13
80 INT277430 Wibg Positive_regulation of Gene_expression of Gdnf 1 0.01 0.6 0.13
81 INT193548 Gdnf Positive_regulation of Ephb1 1 0.40 0.34 0.13
82 INT141281 ARTN Regulation of Gdnf 1 0.48 0.32 0.12
83 INT141279 Nrtn Regulation of Gdnf 1 0.14 0.32 0.12
84 INT141280 PSPN Regulation of Gdnf 1 0.48 0.32 0.12
85 INT96518 Regulation of Gdnf Positive_regulation of Ret 1 0.00 0.23 0.11
86 INT213554 Gdnf Regulation of Bdnf 1 0.13 0.14 0.1
87 INT213550 Bdnf Regulation of Gdnf 1 0.13 0.14 0.1
88 INT96519 Gdnf Positive_regulation of Ret 1 0.00 0.22 0.1
89 INT356275 Gdnf Positive_regulation of Phosphorylation of Mapk1 1 0.05 0.21 0.09
90 INT242594 Binding of Gdnf and Ret 1 0.21 0 0.08
91 INT326381 Binding of Gdnf and Pcdhb16 1 0.00 0.3 0.08
92 INT205119 Binding of HIVEP1 and GREM1 1 0.00 2.24 0.08
93 INT326382 Binding of Gdnf and Ncam1 1 0.01 0.3 0.08
94 INT277431 Positive_regulation of Grm3 Positive_regulation of Gene_expression of Gdnf 1 0.18 0 0.07
95 INT277432 Ptpn2 Positive_regulation of Gdnf 1 0.29 1.41 0.06
96 INT235640 Binding of GATA3 and Mrgpre 1 0.01 0.8 0.04
97 INT79985 Gdnf Negative_regulation of Negative_regulation of GAD1 1 0.04 0.46 0.04
98 INT79986 Gdnf Negative_regulation of Gene_expression of GAD1 1 0.03 0.46 0.04
99 INT242601 Gdnf Positive_regulation of Chat 1 0.29 0.15 0.03
100 INT277429 Ptpn2 Regulation of Gdnf 1 0.34 0.47 0.03
101 INT277427 Ptpn2 Positive_regulation of Gene_expression of Gdnf 1 0.32 0.47 0.03
102 INT277428 Positive_regulation of Ptpn2 Positive_regulation of Gdnf 1 0.29 0.47 0.03
103 INT293869 Binding of COL2A1 and GREM1 1 0.00 1.11 0
104 INT342043 Binding of Gdnf and Unc5a 1 0.20 0.78 0
105 INT293868 Binding of GREM1 and OCM 1 0.00 1.11 0
106 INT264805 Binding of GREM1 and CNNM2 1 0.00 0.24 0
107 INT342038 Binding of Gdnf and Ntn1 1 0.01 0.78 0
108 INT356271 Gdnf Positive_regulation of Positive_regulation of Mapk1 1 0.05 0.25 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for ureteric bud formation. They are ordered first by their pain relevance and then by number of times they were reported in ureteric bud formation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT74389 Gene_expression of Gdnf 131 0.78 58.52 57.06
2 INT48890 Gene_expression of Gdnf 91 0.77 28.62 31.49
3 INT77793 Positive_regulation of Gdnf 54 0.70 23.76 25.08
4 INT102897 Positive_regulation of Gene_expression of Gdnf 34 0.69 11.13 13.28
5 INT79981 Positive_regulation of Gene_expression of Gdnf 27 0.70 12.49 10.77
6 INT82950 Positive_regulation of Gdnf 36 0.51 11.72 10.5
7 INT85844 Regulation of Gdnf 18 0.50 11.08 10.43
8 INT98111 Negative_regulation of Gdnf 12 0.59 10.85 9.29
9 INT77795 Localization of Gdnf 26 0.81 6.29 8.55
10 INT77794 Binding of Gdnf 15 0.48 8.38 8.22
11 INT92003 Positive_regulation of Transcription of Gdnf 10 0.66 5.54 7.84
12 INT87546 Transcription of Gdnf 15 0.71 7.49 7.76
13 INT92001 Regulation of Gene_expression of Gdnf 12 0.62 6.62 6.65
14 INT87548 Negative_regulation of Gene_expression of Gdnf 9 0.54 5.67 5.94
15 INT115087 Negative_regulation of Gdnf 10 0.51 5.78 5.73
16 INT78626 Regulation of Gdnf 7 0.45 3.3 4.64
17 INT116011 Positive_regulation of Gata3 5 0.31 3.17 4.21
18 INT202417 Gene_expression of Gata3 16 0.61 7.84 4.12
19 INT78625 Regulation of Gene_expression of Gdnf 7 0.37 2.5 3.47
20 INT133080 Gene_expression of GATA3 15 0.61 5.64 2.89
21 INT209744 Transcription of Gdnf 5 0.67 1.36 2.84
22 INT202419 Positive_regulation of Gene_expression of Gata3 6 0.52 5.47 2.6
23 INT144366 Negative_regulation of Positive_regulation of Gdnf 4 0.41 1.43 2.41
24 INT98650 Positive_regulation of Localization of Gdnf 4 0.68 0.94 2.27
25 INT180801 Regulation of Binding of Gdnf 1 0.20 1.31 2.03
26 INT209745 Positive_regulation of Transcription of Gdnf 4 0.58 0.97 1.91
27 INT176629 Gene_expression of GREM1 9 0.10 6.89 1.66
28 INT93182 Binding of Gdnf 7 0.35 1.96 1.64
29 INT98651 Regulation of Positive_regulation of Gdnf 3 0.44 0.97 1.58
30 INT116014 Transcription of Gata3 4 0.63 2.24 1.46
31 INT116015 Regulation of Gata3 3 0.22 1.41 1.42
32 INT116008 Binding of Gata3 2 0.34 1.37 1.41
33 INT87547 Negative_regulation of Transcription of Gdnf 1 0.58 1.24 1.4
34 INT98653 Negative_regulation of Localization of Gdnf 1 0.57 0.31 1.35
35 INT116016 Positive_regulation of Positive_regulation of Gata3 2 0.21 0.5 1.28
36 INT133079 Positive_regulation of Gene_expression of GATA3 3 0.50 1.03 1.11
37 INT180795 Positive_regulation of Positive_regulation of Gdnf 2 0.29 0.1 1.07
38 INT108985 Negative_regulation of Regulation of Gdnf 1 0.43 1.11 1.04
39 INT121947 Negative_regulation of Positive_regulation of Gdnf 1 0.20 0.07 0.76
40 INT116012 Regulation of Positive_regulation of Gata3 1 0.20 0.07 0.71
41 INT116006 Positive_regulation of Transcription of Gata3 1 0.21 0.07 0.7
42 INT116010 Positive_regulation of Binding of Gata3 1 0.31 0.07 0.7
43 INT236094 Localization of Gdnf 4 0.70 2.51 0.68
44 INT209746 Regulation of Positive_regulation of Gdnf 2 0.37 0.11 0.68
45 INT202416 Negative_regulation of Gata3 2 0.32 1.17 0.64
46 INT17840 Negative_regulation of GATA3 3 0.41 1.96 0.63
47 INT205470 Positive_regulation of GATA3 4 0.33 2.53 0.61
48 INT169167 Positive_regulation of GREM1 1 0.08 1.83 0.6
49 INT290660 Negative_regulation of Gene_expression of Gata3 1 0.25 1.52 0.6
50 INT226481 Negative_regulation of Gene_expression of GATA3 1 0.06 1.41 0.57
51 INT98112 Positive_regulation of Negative_regulation of Gdnf 1 0.05 0.44 0.57
52 INT144053 Transcription of GATA3 1 0.67 0.89 0.54
53 INT299799 Negative_regulation of Negative_regulation of GATA3 1 0.09 1.32 0.47
54 INT127069 Regulation of Localization of Gdnf 1 0.34 0.46 0.46
55 INT148433 Negative_regulation of Binding of Gdnf 1 0.41 1.14 0.4
56 INT242536 Negative_regulation of Gene_expression of Gdnf 1 0.30 0.06 0.28
57 INT177609 Negative_regulation of GREM1 4 0.06 1.73 0.19
58 INT264812 Binding of GREM1 1 0.00 0.53 0.19
59 INT277419 Positive_regulation of Positive_regulation of Gdnf 1 0.47 0 0.12
60 INT194746 Phosphorylation of Gata3 1 0.10 0.08 0.12
61 INT277418 Regulation of Binding of Gdnf 1 0.42 0 0.08
62 INT347981 Positive_regulation of Phosphorylation of Gdnf 1 0.11 0.79 0.07
63 INT347993 Regulation of Phosphorylation of Gdnf 1 0.10 0.87 0.07
64 INT347980 Phosphorylation of Gdnf 1 0.19 0.79 0.07
65 INT185989 Localization of GREM1 2 0.11 2.41 0.05
66 INT197017 Binding of GATA3 2 0.36 0.94 0.04
67 INT333344 Transcription of GREM1 1 0.03 0.16 0
68 INT355096 Phosphorylation of GREM1 1 0.02 0.25 0
69 INT235637 Localization of GATA3 1 0.73 0.55 0
70 INT293878 Positive_regulation of Localization of GREM1 1 0.01 0.47 0
71 INT355082 Positive_regulation of Phosphorylation of GREM1 1 0.01 0.25 0
72 INT293875 Positive_regulation of Gene_expression of GREM1 1 0.01 0.47 0
73 INT331205 Protein_catabolism of Gdnf 1 0.03 0.57 0
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