GO:0060684

From wiki-pain
Jump to: navigation, search
Name epithelial-mesenchymal cell signaling
Categary Process
Go Slim No
Go Link GO:0060684
Unique Molecular Interactions 55
Total Molecular Interactions 74
Total Single Events 484
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for epithelial-mesenchymal cell signaling. They are ordered first by their pain relevance and then by number of times they were reported for epithelial-mesenchymal cell signaling. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT297340 Apoe Regulation of Binding of Smo 1 0.10 1.1 0.6
2 INT97949 Negative_regulation of NRP2 Negative_regulation of Positive_regulation of CDC42 1 0.06 0.72 0.51
3 INT97953 ST3GAL3 Positive_regulation of CDC42 1 0.09 0.7 0.5
4 INT297342 Binding of Gnb5 and Smo 1 0.02 1.67 0.34
5 INT285567 Binding of IL1B and Cdc42 1 0.03 0.77 0.31
6 INT292565 MAP3K5 Positive_regulation of Positive_regulation of CDC42 1 0.02 0 0.23
7 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19
8 INT345343 PTCH1 Regulation of Negative_regulation of SMO 1 0.09 2.3 0.13
9 INT287267 EGF Positive_regulation of CDC42 1 0.12 0.16 0.11
10 INT262751 Binding of PTCH1 and SMO 1 0.25 1.29 0.1
11 INT270464 Binding of Shh and Smo 1 0.07 1.3 0.08
12 INT290906 Shh Positive_regulation of Egfr 1 0.23 0 0.08
13 INT298349 HES3 Positive_regulation of Shh 1 0.12 0.14 0.07
14 INT290905 Gene_expression of Shh Positive_regulation of Gene_expression of Angpt1 1 0.14 0 0.06
15 INT210261 Bmp4 Regulation of Gene_expression of Tff3 1 0.64 0 0.05
16 INT262757 SMO Positive_regulation of Regulation of GLI1 1 0.34 0.6 0.04
17 INT270458 Binding of Gli1 and Smo 1 0.00 0.65 0.04
18 INT213563 Binding of Ctnnd2 and Shh 1 0.27 0.09 0.04
19 INT270459 Binding of Shh and Gli1 1 0.02 0.65 0.04
20 INT352014 Shh Positive_regulation of Gene_expression of Pax1 1 0.29 0.07 0.03
21 INT181083 Binding of Akt1 and Cdc42 1 0.00 0.79 0.03
22 INT311655 Shh Positive_regulation of Gene_expression of Fgf8 1 0.31 0.18 0.03
23 INT270462 Shh Positive_regulation of Ccnd1 1 0.10 0.6 0.03
24 INT213559 Binding of Egf and Shh 1 0.17 0.07 0.03
25 INT290910 Pkm2 Negative_regulation of Shh 1 0.07 0.06 0
26 INT314850 Shh Regulation of Atoh7 1 0.45 0.22 0
27 INT290908 Regulation of Shh Positive_regulation of Ntn1 1 0.12 0 0
28 INT205975 Binding of PTCH1 and Smo 1 0.02 0.72 0
29 INT290911 Gene_expression of Shh Positive_regulation of Pkm2 1 0.07 0 0
30 INT290904 Shh Positive_regulation of Prkcg 1 0.26 0.06 0
31 INT290900 Prkcg Regulation of Shh 1 0.23 0 0
32 INT234996 Ctnnd1 Positive_regulation of CDC42 1 0.01 0.07 0
33 INT205974 Smo Positive_regulation of GLI1 1 0.04 0.66 0
34 INT352525 SLC25A16 Negative_regulation of SMO 1 0.00 1.1 0
35 INT290944 Shh Positive_regulation of VEGFA 1 0.04 0.05 0
36 INT270461 Shh Regulation of Gene_expression of Ptch1 1 0.48 0.07 0
37 INT196023 Bmp2 Negative_regulation of Gene_expression of Bmp4 1 0.09 0.07 0
38 INT196021 Bmp2 Positive_regulation of Gene_expression of Bmp4 1 0.09 0.08 0
39 INT249149 Binding of Cdc42 and Was 1 0.08 0.18 0
40 INT270471 Shh Regulation of VEGFA 1 0.39 0.08 0
41 INT290898 Shh Positive_regulation of Nos2 1 0.46 0.05 0
42 INT205965 Binding of Ptch1 and Smo 1 0.03 0.72 0
43 INT270466 Ptch1 Regulation of Gene_expression of Shh 1 0.48 0.07 0
44 INT196022 Bmp7 Regulation of Bmp4 1 0.06 0.06 0
45 INT270460 Shh Positive_regulation of Gene_expression of Angpt1 1 0.04 0.08 0
46 INT270470 Shh Regulation of Gene_expression of VEGFA 1 0.39 0.15 0
47 INT290907 Shh Positive_regulation of Ntn1 1 0.32 0.05 0
48 INT270469 Shh Positive_regulation of VEGFA 1 0.29 0.12 0
49 INT181085 Binding of Cdc42 and Errfi1 1 0.08 0.67 0
50 INT270468 Shh Positive_regulation of Gene_expression of VEGFA 1 0.44 0.08 0
51 INT264737 Hes1 Regulation of Shh 1 0.19 0.13 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for epithelial-mesenchymal cell signaling. They are ordered first by their pain relevance and then by number of times they were reported in epithelial-mesenchymal cell signaling. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT144973 Gene_expression of Shh 9 0.77 4.32 1.96
2 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77
3 INT120088 Gene_expression of Bmp4 37 0.73 13.89 1.73
4 INT183068 Gene_expression of SMO 2 0.17 0.27 1.2
5 INT97955 Positive_regulation of CDC42 8 0.49 2.47 1.19
6 INT253191 Positive_regulation of Gene_expression of Shh 2 0.66 2.57 1.14
7 INT165530 Positive_regulation of Shh 4 0.69 1.21 1.05
8 INT161682 Positive_regulation of Cdc42 8 0.53 4.55 0.9
9 INT142122 Regulation of Gene_expression of Bmp4 5 0.43 2.69 0.86
10 INT210247 Positive_regulation of Bmp4 6 0.65 4.36 0.8
11 INT270447 Binding of Smo 2 0.07 2.61 0.78
12 INT96422 Gene_expression of Bmp4 18 0.69 3.26 0.63
13 INT205957 Negative_regulation of Smo 4 0.08 2.57 0.6
14 INT180107 Regulation of Cdc42 3 0.16 0.18 0.6
15 INT97956 Negative_regulation of CDC42 3 0.27 1.58 0.55
16 INT206484 Localization of Shh 2 0.75 1.14 0.46
17 INT142124 Binding of Bmp4 1 0.35 0.46 0.45
18 INT232798 Positive_regulation of Gene_expression of Shh 7 0.70 1.49 0.44
19 INT180688 Transcription of Bmp4 3 0.58 0.35 0.41
20 INT180702 Positive_regulation of Transcription of Bmp4 3 0.42 0.35 0.41
21 INT208559 Negative_regulation of Gene_expression of Shh 8 0.43 1.58 0.38
22 INT356400 Transcription of Smo 1 0.02 0.05 0.3
23 INT277474 Positive_regulation of Gene_expression of SMO 1 0.11 0 0.29
24 INT216120 Negative_regulation of SMO 2 0.49 3.05 0.27
25 INT232795 Positive_regulation of Shh 2 0.70 3.68 0.26
26 INT183881 Localization of CDC42 3 0.49 1.92 0.23
27 INT142121 Positive_regulation of Gene_expression of Bmp4 3 0.47 7 0.21
28 INT183876 Regulation of CDC42 3 0.30 1.94 0.19
29 INT120085 Negative_regulation of Gene_expression of Bmp4 5 0.55 0.61 0.17
30 INT232799 Regulation of Gene_expression of Shh 3 0.27 1.04 0.16
31 INT253177 Negative_regulation of Gene_expression of Shh 2 0.55 0.63 0.16
32 INT197290 Gene_expression of Cdc42 9 0.35 2.52 0.15
33 INT253190 Localization of Shh 2 0.77 1.06 0.13
34 INT253183 Negative_regulation of Shh 8 0.55 2.13 0.12
35 INT206133 Binding of CDC42 3 0.25 0.8 0.12
36 INT196033 Negative_regulation of Gene_expression of Bmp4 3 0.21 0.45 0.09
37 INT270442 Transcription of Shh 1 0.53 0.25 0.09
38 INT213515 Binding of Shh 8 0.37 1.92 0.08
39 INT197282 Positive_regulation of Gene_expression of Cdc42 3 0.26 0.12 0.08
40 INT270453 Regulation of Shh 1 0.27 0.83 0.08
41 INT256862 Regulation of Shh 1 0.25 0 0.07
42 INT210243 Negative_regulation of Bmp4 1 0.55 0.55 0.07
43 INT345344 Regulation of SMO 1 0.23 1.07 0.06
44 INT206169 Gene_expression of CDC42 2 0.26 1.05 0.05
45 INT270445 Positive_regulation of Localization of Shh 1 0.44 0.13 0.05
46 INT206167 Positive_regulation of Gene_expression of CDC42 1 0.08 0.05 0.05
47 INT262772 Binding of SMO 1 0.27 0.59 0.05
48 INT196030 Positive_regulation of Bmp4 6 0.62 2.55 0.04
49 INT208560 Negative_regulation of Shh 2 0.59 2.22 0.04
50 INT262777 Localization of SMO 1 0.59 0.6 0.04
51 INT210238 Positive_regulation of Negative_regulation of Bmp4 1 0.47 0 0.04
52 INT253182 Positive_regulation of Positive_regulation of Bmp4 1 0.45 0.58 0.04
53 INT253187 Negative_regulation of Transcription of Shh 1 0.41 0.55 0.03
54 INT253181 Transcription of Shh 1 0.68 0.54 0.03
55 INT196034 Positive_regulation of Gene_expression of Bmp4 4 0.45 0.63 0
56 INT260779 Negative_regulation of Bmp4 4 0.23 0.94 0
57 INT254795 Negative_regulation of Cdc42 2 0.12 1.53 0
58 INT196027 Binding of Bmp4 2 0.13 0.97 0
59 INT142119 Regulation of Bmp4 2 0.58 0.29 0
60 INT270614 Localization of Cdc42 1 0.55 0.95 0
61 INT252242 Gene_expression of Smo 1 0.01 0.23 0
62 INT197294 Regulation of Gene_expression of Cdc42 1 0.13 0 0
63 INT339667 Localization of Bmp4 1 0.38 0.27 0
64 INT282269 Binding of Cdc42 1 0.08 0.33 0
65 INT287281 Positive_regulation of Positive_regulation of CDC42 1 0.26 0 0
66 INT282272 Positive_regulation of Binding of Cdc42 1 0.11 0.33 0
67 INT290918 Negative_regulation of Positive_regulation of Shh 1 0.41 0.25 0
68 INT205956 Localization of Smo 1 0.06 0.71 0
69 INT290929 Binding of Shh 1 0.31 0.1 0
70 INT290927 Regulation of Positive_regulation of Shh 1 0.23 0 0
71 INT270449 Negative_regulation of Positive_regulation of Shh 1 0.43 0.24 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox