GO:0060716

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Name labyrinthine layer blood vessel development
Categary Process
Go Slim No
Go Link GO:0060716
Unique Molecular Interactions 1026
Total Molecular Interactions 1467
Total Single Events 9751
Pain Genes Associated 15

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for labyrinthine layer blood vessel development. They are ordered first by their pain relevance and then by number of times they were reported for labyrinthine layer blood vessel development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT132225 Negative_regulation of Binding of Akt1 and Sh2d6 1 0.10 3.92 7.2
2 INT132231 Negative_regulation of Binding of Akt1 and Pik3cg 1 0.34 1.96 3.6
3 INT317522 Akt1 Positive_regulation of Phosphorylation of Nos1 1 0.43 0.4 3.13
4 INT168758 Hist1h1t Positive_regulation of Phosphorylation of Akt1 2 0.02 0.44 2.79
5 INT317551 Binding of Akt1 and Oprm1 1 0.19 0.21 2.74
6 INT223866 Ltp Positive_regulation of Positive_regulation of Mapk1 2 0.46 0.75 2.61
7 INT238914 Positive_regulation of CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 3.22 2.35
8 INT121726 Ngf Positive_regulation of Phosphorylation of Akt1 1 0.37 1.4 2.34
9 INT114432 Oprl1 Positive_regulation of Akt1 1 0.18 0.08 2.2
10 INT281084 Prkaca Positive_regulation of Mapk1 2 0.25 0 2.06
11 INT132229 Binding of Akt1 and Sh2d6 1 0.09 0.98 1.8
12 INT169464 Akt1 Positive_regulation of Egfr 1 0.28 1.63 1.7
13 INT322412 PPBP Negative_regulation of Phosphorylation of Akt1 1 0.01 0 1.65
14 INT144280 ACP1 Negative_regulation of Phosphorylation of MAPK1 1 0.37 0.78 1.56
15 INT169800 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Mapk1 1 0.39 1.04 1.45
16 INT214372 Ptprq Positive_regulation of Akt1 1 0.04 0.88 1.43
17 INT261831 Mapk1 Negative_regulation of Hspg2 1 0.00 1.26 1.42
18 INT148450 Gene_expression of Inhbe Positive_regulation of Mapk1 1 0.07 1.35 1.41
19 INT161670 H2-M3 Positive_regulation of Positive_regulation of Mapk1 1 0.14 0.73 1.41
20 INT214369 Pik3cb Positive_regulation of Akt1 1 0.56 0.87 1.41
21 INT106062 Positive_regulation of Oprl1 Positive_regulation of Mapk1 1 0.13 0.16 1.35
22 INT166388 Binding of Gnb2l1 and Mapk1 1 0.49 0.49 1.21
23 INT121191 KCNMA1 Positive_regulation of Phosphorylation of MAPK1 1 0.06 0.61 1.18
24 INT169557 Cacna1h Positive_regulation of Mapk1 1 0.07 0.91 1.17
25 INT238916 CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 1.61 1.17
26 INT161510 Tlr4 Positive_regulation of Mapk1 1 0.14 0.3 1.16
27 INT317548 Positive_regulation of Akt1 Positive_regulation of Prkca 1 0.15 0 1.11
28 INT317516 Binding of Oprm1 and Negative_regulation of Positive_regulation of Akt1 1 0.17 0.1 1.11
29 INT323175 PRKCA Positive_regulation of Akt1 1 0.02 0 1.1
30 INT151218 Negative_regulation of SIGMAR1 Negative_regulation of Positive_regulation of Akt1 1 0.00 0.26 1.03
31 INT101067 MAP3K15 Positive_regulation of MAPK1 1 0.21 0.47 1.03
32 INT317554 Akt1 Regulation of Negative_regulation of Oprm1 1 0.21 0.07 1
33 INT140652 IGF1 Positive_regulation of Phosphorylation of MAPK1 1 0.26 0.63 0.98
34 INT317567 Binding of Akt1 and Nos1 1 0.22 0 0.96
35 INT100018 TNF Positive_regulation of MAPK1 3 0.24 1.56 0.94
36 INT144281 ACP1 Negative_regulation of Positive_regulation of MAPK1 1 0.27 0.58 0.94
37 INT137923 VEGFA Positive_regulation of Phosphorylation of Akt1 1 0.05 0 0.93
38 INT144285 ACP1 Negative_regulation of MAPK1 1 0.37 0.58 0.93
39 INT223871 Ltp Positive_regulation of Gene_expression of Mapk1 1 0.33 0 0.93
40 INT114883 Akt1 Regulation of Pik3r1 2 0.16 0.65 0.92
41 INT302828 Mapkapk5 Positive_regulation of Mapk1 1 0.07 1.38 0.91
42 INT343918 IgG Positive_regulation of Phosphorylation of MAPK1 1 0.01 3.57 0.91
43 INT317541 Oprd1 Negative_regulation of Akt1 1 0.06 0 0.91
44 INT249012 Binding of Akt1 and Gabrg1 1 0.01 0 0.9
45 INT111924 Cpb2 Negative_regulation of Positive_regulation of Plg 1 0.02 1.29 0.9
46 INT132226 Binding of Akt1 and Pik3cg 1 0.30 0.49 0.9
47 INT188196 LIF Regulation of MAPK1 1 0.21 2.26 0.87
48 INT199109 Binding of Akt1 and Arhgdia 1 0.02 2.73 0.87
49 INT188214 OSM Regulation of MAPK1 1 0.20 2.27 0.87
50 INT190183 MAPK1 Regulation of CDCP1 1 0.00 1.19 0.85
51 INT317556 Phosphorylation of Gopc Positive_regulation of Akt1 1 0.10 0.08 0.82
52 INT317514 Akt1 Regulation of Localization of Oprm1 1 0.21 0.07 0.82
53 INT262572 Ngf Positive_regulation of Mapk1 2 0.04 0.52 0.81
54 INT228255 Binding of Akt1 and Pten 2 0.43 1.78 0.8
55 INT161520 H2-M3 Regulation of Positive_regulation of Mapk1 1 0.09 0.47 0.79
56 INT132977 Tac1 Positive_regulation of Mapk1 1 0.06 0.17 0.79
57 INT117909 Mastl Positive_regulation of Mapk1 1 0.04 0 0.79
58 INT111888 Akt1 Regulation of Regulation of Oprm1 1 0.04 0 0.77
59 INT134043 Jak2 Positive_regulation of Akt1 1 0.31 0.22 0.76
60 INT163830 ERBB2 Positive_regulation of MAPK1 1 0.06 1.63 0.76
61 INT335592 Ltp Positive_regulation of Positive_regulation of Akt1 1 0.01 0.19 0.74
62 INT106527 Akt1 Positive_regulation of Jun 1 0.05 0.53 0.74
63 INT128404 Mapk1 Positive_regulation of Phosphorylation of Gja1 1 0.65 0.73 0.73
64 INT276213 Pten Regulation of Phosphorylation of Akt1 1 0.51 0.61 0.72
65 INT261378 Nsdhl Negative_regulation of Gene_expression of Flvcr2 1 0.01 0.34 0.7
66 INT166386 Mapk1 Regulation of Gene_expression of Gnb2l1 1 0.46 0.25 0.7
67 INT320633 Positive_regulation of MAPK1 Regulation of BCL2 1 0.04 1.21 0.7
68 INT194685 MAPK1 Regulation of Gene_expression of IL10 1 0.06 1.18 0.7
69 INT320634 Positive_regulation of MAPK1 Regulation of PBX2 1 0.03 1.21 0.7
70 INT223868 Mapk1 Positive_regulation of Creb1 2 0.17 0.34 0.68
71 INT223876 Mapk1 Positive_regulation of Atf6b 1 0.10 0 0.68
72 INT298728 Akt1 Positive_regulation of Rela 1 0.01 1.03 0.67
73 INT289357 Ngfr Positive_regulation of Akt1 1 0.03 3.1 0.66
74 INT211916 Fig4 Positive_regulation of Mapk1 1 0.13 0.25 0.66
75 INT191332 AMPH Positive_regulation of Mapk1 1 0.76 0 0.66
76 INT308668 Akt1 Positive_regulation of Nos3 3 0.05 4.61 0.65
77 INT296793 Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.75 0.65
78 INT124477 MAP2K1 Positive_regulation of Positive_regulation of MAPK1 1 0.12 1.35 0.65
79 INT296791 Positive_regulation of Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.8 0.65
80 INT148173 Positive_regulation of Grm5 Positive_regulation of Phosphorylation of Mapk1 1 0.01 0.45 0.65
81 INT134047 Fitm1 Positive_regulation of Phosphorylation of Akt1 1 0.05 0.21 0.63
82 INT134044 Positive_regulation of Fitm1 Positive_regulation of Phosphorylation of Akt1 1 0.05 0.21 0.63
83 INT281092 Adcy1 Positive_regulation of Mapk1 1 0.21 0 0.63
84 INT281090 Prkacb Positive_regulation of Mapk1 1 0.06 0 0.62
85 INT200808 Binding of Akt1 and Insrr 2 0.00 0.98 0.61
86 INT282286 Akt1 Positive_regulation of Pak1 1 0.15 0.24 0.61
87 INT139901 Ins1 Positive_regulation of Akt1 9 0.31 4.58 0.6
88 INT291262 Positive_regulation of INS Positive_regulation of Mapk1 1 0.03 1.78 0.58
89 INT248994 Binding of Akt1 and Ptar1 1 0.00 0 0.58
90 INT291258 INS Positive_regulation of Mapk1 1 0.04 1.77 0.58
91 INT115146 MAPK1 Positive_regulation of EGR1 3 0.13 2.43 0.57
92 INT148172 Mapk1 Positive_regulation of Phosphorylation of Kcnd2 1 0.49 0.55 0.57
93 INT323176 PRKCA Positive_regulation of Phosphorylation of Akt1 1 0.02 0 0.56
94 INT302832 Tnfsf10 Positive_regulation of Akt1 1 0.04 1.63 0.56
95 INT201949 CXCL10 Positive_regulation of Phosphorylation of MAPK1 1 0.15 0.79 0.55
96 INT121994 EGF Positive_regulation of Positive_regulation of MAPK1 1 0.25 0 0.55
97 INT114064 Agtr2 Positive_regulation of Phosphorylation of Akt1 1 0.24 0.41 0.54
98 INT282284 Cpox Positive_regulation of Akt1 1 0.02 0.47 0.54
99 INT282282 Ptger2 Positive_regulation of Akt1 1 0.03 0.47 0.54
100 INT162994 Binding of Akt1 and Trib3 1 0.04 0.09 0.54
101 INT323146 PRKCA Positive_regulation of MAPK1 1 0.02 0 0.54
102 INT127320 Gpx3 Regulation of Akt1 2 0.00 3.11 0.53
103 INT85125 IL3 Positive_regulation of MAPK1 1 0.30 0.81 0.53
104 INT85121 CSF2 Positive_regulation of MAPK1 1 0.07 0.8 0.53
105 INT317523 Oprm1 Positive_regulation of Gene_expression of Akt1 1 0.32 0.05 0.53
106 INT85115 IL5 Positive_regulation of MAPK1 1 0.14 0.81 0.53
107 INT109307 Pik3r1 Positive_regulation of Phosphorylation of Akt1 1 0.29 0.4 0.53
108 INT317574 Oprm1 Positive_regulation of Akt1 1 0.22 0.05 0.52
109 INT171909 MAPK8 Positive_regulation of Gene_expression of MAPK1 1 0.08 1.55 0.52
110 INT171910 MAPK1 Positive_regulation of MAPK9 1 0.10 1.55 0.52
111 INT201939 CXCL10 Positive_regulation of MAPK1 1 0.11 0.72 0.52
112 INT171906 MAPK1 Positive_regulation of Gene_expression of MAPK14 1 0.08 1.55 0.52
113 INT171914 MAPK8IP3 Positive_regulation of Gene_expression of MAPK1 1 0.06 1.55 0.52
114 INT122872 SEMA6A Positive_regulation of MAPK1 1 0.56 0 0.52
115 INT131368 MAPK1 Positive_regulation of Bcar3 1 0.00 0.37 0.51
116 INT151221 Negative_regulation of SIGMAR1 Negative_regulation of Akt1 1 0.00 0.13 0.51
117 INT131369 MAPK1 Positive_regulation of Il4 1 0.01 0.37 0.51
118 INT356286 Ngf Regulation of Positive_regulation of Mapk1 1 0.03 0.76 0.5
119 INT356279 Gdnf Regulation of Positive_regulation of Mapk1 1 0.03 0.76 0.5
120 INT194676 Negative_regulation of MAPK1 Negative_regulation of Gene_expression of IL10 1 0.05 0.34 0.5
121 INT102844 Pdc Regulation of Akt1 1 0.03 0 0.49
122 INT102553 HGF Positive_regulation of Phosphorylation of MAPK1 1 0.40 0.49 0.48
123 INT134042 Jak2 Regulation of Akt1 1 0.18 0.13 0.47
124 INT309126 Edc4 Positive_regulation of Akt1 1 0.02 0.99 0.47
125 INT185917 Binding of AR and MAPK1 1 0.07 0.5 0.47
126 INT309144 Dlat Positive_regulation of Akt1 1 0.03 0.99 0.47
127 INT276207 Binding of Akt1 and Myo1f 1 0.11 0.05 0.47
128 INT102555 HGF Positive_regulation of MAPK1 1 0.38 0.47 0.47
129 INT125568 Binding of Casr and Ncoa6 3 0.50 1.13 0.46
130 INT265646 Binding of Mapk1 and Mapk14 1 0.01 1.53 0.46
131 INT114065 Akt1 Regulation of Gene_expression of Insr 1 0.13 0.28 0.46
132 INT276218 Binding of Akt1 and Pten 1 0.26 0.08 0.46
133 INT254198 Mapk1 Positive_regulation of Mapk8 1 0.01 0.87 0.46
134 INT254216 Mapk14 Positive_regulation of Mapk1 1 0.02 0.87 0.46
135 INT254222 Mapk1 Positive_regulation of Mapk14 1 0.02 0.86 0.46
136 INT108332 EGF Positive_regulation of Phosphorylation of MAPK1 5 0.48 1.85 0.45
137 INT190870 BDNF Positive_regulation of Phosphorylation of Mapk1 1 0.12 0.54 0.44
138 INT343846 MAPK1 Positive_regulation of FOS 1 0.04 1.29 0.44
139 INT139900 Kcne2 Positive_regulation of Akt1 1 0.06 2.95 0.44
140 INT223863 Positive_regulation of Mapk1 Positive_regulation of Positive_regulation of Ltp 1 0.31 0 0.43
141 INT264473 Il1a Positive_regulation of Mapk1 1 0.00 0 0.43
142 INT188211 IL6 Regulation of MAPK1 1 0.16 1.13 0.43
143 INT265647 Binding of Ephb1 and Mapk1 1 0.00 1.48 0.43
144 INT264471 Il1a Positive_regulation of Gene_expression of Mapk1 1 0.01 0 0.43
145 INT348785 Ins1 Positive_regulation of Phosphorylation of Akt1 1 0.17 3.5 0.42
146 INT322396 Hist1h1t Positive_regulation of Akt1 1 0.01 0 0.42
147 INT238913 MAPK3 Regulation of Positive_regulation of MAPK1 1 0.11 0.39 0.42
148 INT161521 Negative_regulation of H2-M3 Positive_regulation of Mapk1 1 0.14 0.41 0.42
149 INT322395 Akt1 Regulation of Pik3cb 1 0.08 0 0.42
150 INT194722 Negative_regulation of MAPK1 Negative_regulation of Gene_expression of CRP 1 0.09 1.49 0.41
151 INT122749 Cyp3a23/3a1 Positive_regulation of Phosphorylation of Akt1 1 0.07 0.24 0.41
152 INT261374 Nsdhl Regulation of Esr2 1 0.05 0.76 0.41
153 INT274864 Negative_regulation of Mapk1 Negative_regulation of Gene_expression of TNF 1 0.05 1.15 0.41
154 INT161522 H2-M3 Positive_regulation of Mapk1 1 0.15 0.41 0.41
155 INT274867 Negative_regulation of Mapk1 Negative_regulation of TNF 1 0.03 1.15 0.41
156 INT261652 Binding of MAPK1 and PSEN1 1 0.22 1.25 0.41
157 INT261370 Nsdhl Regulation of Esr1 1 0.01 0.75 0.41
158 INT124260 Plat Positive_regulation of Mapk1 1 0.14 0.81 0.41
159 INT194705 Negative_regulation of MAPK1 Negative_regulation of Positive_regulation of IK 1 0.00 1.46 0.41
160 INT276216 Binding of Akt1 and Ins1 2 0.03 2.61 0.4
161 INT231842 Pcdh8 Positive_regulation of Akt1 1 0.00 1.59 0.4
162 INT113474 MAPK1 Negative_regulation of TNF 1 0.13 0.23 0.4
163 INT322409 Positive_regulation of OPRM1 Positive_regulation of Phosphorylation of Akt1 1 0.04 0 0.4
164 INT152237 Mapk1 Positive_regulation of Localization of Tlr4 1 0.33 0.13 0.39
165 INT166155 Ccr9 Positive_regulation of Akt1 1 0.58 2.14 0.39
166 INT152239 Mapk1 Positive_regulation of Localization of Nfkb1 1 0.29 0.13 0.39
167 INT194713 MAPK1 Regulation of Gene_expression of TNF 1 0.10 1.66 0.38
168 INT146611 Ins1 Positive_regulation of Phosphorylation of Akt1 9 0.23 4.34 0.37
169 INT300609 Binding of Ctnnb1 and Wnt2 1 0.02 0.25 0.37
170 INT207643 Prkca Positive_regulation of Mapk1 1 0.09 0.17 0.37
171 INT304501 Binding of Ephb1 and Mapk1 1 0.18 0.69 0.36
172 INT274941 Ephb2 Regulation of Phosphorylation of Mapk1 1 0.19 0 0.36
173 INT304505 Binding of Mapk1 and Uts2d 1 0.01 0.64 0.36
174 INT148243 Binding of Akt1 and Kit 1 0.03 0.44 0.35
175 INT122758 Positive_regulation of Helt Positive_regulation of Akt1 1 0.00 0.2 0.35
176 INT288208 Binding of Mapk14 and Positive_regulation of Akt1 1 0.01 0.42 0.35
177 INT304532 Binding of Mdk and Mapk1 1 0.02 0.63 0.35
178 INT274865 Positive_regulation of Mapk1 Negative_regulation of Gene_expression of TNF 1 0.04 1.08 0.35
179 INT304495 Trib3 Positive_regulation of Mapk1 1 0.02 1.4 0.35
180 INT304529 Negative_regulation of Binding of Mdk and Mapk1 1 0.02 0.63 0.35
181 INT122756 Helt Positive_regulation of Akt1 1 0.00 0.2 0.35
182 INT144966 MAPK1 Positive_regulation of Localization of EGR1 1 0.08 0.83 0.35
183 INT124380 Prodh2 Regulation of Wnt2 1 0.00 0.63 0.35
184 INT167156 FPR1 Positive_regulation of MAPK1 1 0.18 0.09 0.35
185 INT309118 Dlat Positive_regulation of Positive_regulation of Akt1 1 0.03 0.32 0.34
186 INT249019 Gabrg1 Positive_regulation of Akt1 1 0.02 0 0.34
187 INT188193 Negative_regulation of EGF Positive_regulation of MAPK1 1 0.28 0.54 0.34
188 INT242162 Binding of Ccnd1 and Wnt2 1 0.10 0.23 0.34
189 INT196820 Negative_regulation of Ppp1cc Positive_regulation of Akt1 1 0.00 0 0.34
190 INT156831 EGF Positive_regulation of MAPK1 2 0.45 0.27 0.33
191 INT190652 Mdk Positive_regulation of Phosphorylation of Mapk1 2 0.50 0.85 0.33
192 INT274866 Mapk1 Positive_regulation of Gene_expression of TNF 1 0.06 0.35 0.33
193 INT214377 Akt1 Regulation of Amph 1 0.15 0 0.33
194 INT167155 FPR1 Positive_regulation of Phosphorylation of MAPK1 1 0.18 0.17 0.33
195 INT337112 Negative_regulation of Nr1d2-rs2 Positive_regulation of Mapk1 1 0.00 0.14 0.33
196 INT280814 Positive_regulation of Mapk1 Positive_regulation of Transcription of Fos 1 0.02 0.06 0.33
197 INT346286 ELANE Positive_regulation of MAPK1 1 0.06 0.65 0.32
198 INT346281 Binding of ELANE and MAPK1 1 0.04 0.65 0.32
199 INT165580 Binding of Akt1 and Grin2b 1 0.02 0.2 0.32
200 INT291240 Map3k8 Positive_regulation of Positive_regulation of Mapk1 1 0.16 0.72 0.32

Single Events

The table below shows the top 100 pain related interactions that have been reported for labyrinthine layer blood vessel development. They are ordered first by their pain relevance and then by number of times they were reported in labyrinthine layer blood vessel development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT95787 Positive_regulation of Mapk1 568 0.70 226.51 220.94
2 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27
3 INT92434 Phosphorylation of Mapk1 287 0.82 91.65 83.46
4 INT48934 Positive_regulation of Mapk1 157 0.70 60.61 61.72
5 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34
6 INT117713 Phosphorylation of Akt1 275 0.82 95.82 54.34
7 INT40777 Positive_regulation of Akt1 163 0.69 59.41 49.43
8 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82
9 INT71786 Phosphorylation of MAPK1 256 0.82 110.09 46.17
10 INT92437 Positive_regulation of Phosphorylation of Mapk1 113 0.70 32.19 40.29
11 INT114751 Gene_expression of Mapk1 137 0.76 60.14 39.98
12 INT102611 Negative_regulation of Positive_regulation of Mapk1 74 0.58 35.57 39.37
13 INT109434 Phosphorylation of Mapk1 110 0.82 61.64 34.05
14 INT48925 Gene_expression of Mapk1 95 0.74 42.21 32.91
15 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81
16 INT117112 Negative_regulation of Mapk1 87 0.56 40.34 31.18
17 INT83708 Negative_regulation of MAPK1 156 0.57 84.93 27.85
18 INT112707 Negative_regulation of Akt1 89 0.59 28.85 27.76
19 INT95788 Positive_regulation of Positive_regulation of Mapk1 83 0.69 24.75 25.84
20 INT12124 Gene_expression of MAPK1 141 0.75 82.4 25.58
21 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53
22 INT40776 Gene_expression of Akt1 99 0.77 34.91 24.39
23 INT117718 Positive_regulation of Phosphorylation of Akt1 112 0.69 39.26 24.09
24 INT91462 Positive_regulation of Phosphorylation of MAPK1 99 0.67 40.28 18.99
25 INT95790 Regulation of Mapk1 55 0.61 21.17 16.31
26 INT111462 Negative_regulation of Phosphorylation of Mapk1 45 0.57 19.49 15.59
27 INT75531 Regulation of MAPK1 70 0.61 34.39 15.42
28 INT128401 Positive_regulation of Positive_regulation of Mapk1 39 0.70 10.88 15.38
29 INT80688 Positive_regulation of Positive_regulation of MAPK1 72 0.69 39.35 14.11
30 INT109304 Positive_regulation of Phosphorylation of Akt1 113 0.69 40.92 13.49
31 INT10433 Positive_regulation of Junb 35 0.70 6.55 12.42
32 INT150676 Positive_regulation of Gene_expression of Mapk1 30 0.45 10.06 12.37
33 INT119396 Regulation of Positive_regulation of Mapk1 22 0.61 7.88 12.25
34 INT9483 Gene_expression of Junb 34 0.78 3.24 12.08
35 INT26534 Regulation of Akt1 34 0.61 14.47 11.86
36 INT75525 Negative_regulation of Positive_regulation of MAPK1 40 0.59 25.15 11.15
37 INT48921 Regulation of Mapk1 25 0.49 19.51 10.41
38 INT75137 Regulation of Akt1 74 0.48 37.89 9.7
39 INT94196 Negative_regulation of Phosphorylation of MAPK1 60 0.59 31.64 9.16
40 INT120967 Negative_regulation of Phosphorylation of Akt1 47 0.57 23.67 8.98
41 INT109432 Negative_regulation of Phosphorylation of Mapk1 19 0.54 7.01 8.98
42 INT104396 Positive_regulation of Positive_regulation of Akt1 44 0.55 14.78 8.69
43 INT126848 Positive_regulation of Phosphorylation of Mapk1 30 0.50 15.94 8.34
44 INT106522 Negative_regulation of Phosphorylation of Akt1 65 0.58 34.44 7.83
45 INT10145 Gene_expression of Plg 28 0.62 12.68 7.46
46 INT9478 Positive_regulation of Gene_expression of Junb 19 0.70 2.34 7.41
47 INT103925 Negative_regulation of Positive_regulation of Akt1 32 0.58 15.19 7.39
48 INT126748 Positive_regulation of Positive_regulation of Akt1 26 0.55 11.15 7.08
49 INT16389 Gene_expression of Plg 80 0.67 36.88 6.74
50 INT10610 Negative_regulation of Plg 22 0.40 11.81 6.74
51 INT48928 Positive_regulation of Gene_expression of Mapk1 19 0.48 9.38 6.59
52 INT139964 Regulation of Phosphorylation of Mapk1 12 0.58 10.04 6.1
53 INT117721 Positive_regulation of Gene_expression of Akt1 22 0.69 6.26 6.08
54 INT114882 Positive_regulation of Gene_expression of Akt1 45 0.69 21.29 6.06
55 INT130111 Regulation of Positive_regulation of MAPK1 14 0.36 11.01 5.9
56 INT71779 Positive_regulation of Gene_expression of MAPK1 27 0.47 21.41 5.39
57 INT124375 Gene_expression of Wnt2 67 0.56 38.03 4.67
58 INT134657 Localization of Akt1 37 0.68 11.58 4.62
59 INT37335 Gene_expression of Nsdhl 45 0.51 24.36 4.58
60 INT122569 Negative_regulation of Gene_expression of Akt1 34 0.54 17.15 4.44
61 INT158416 Localization of Mapk1 19 0.67 5.32 4.18
62 INT75136 Binding of Akt1 27 0.27 8.81 4.15
63 INT15239 Regulation of Junb 13 0.62 1.14 4.1
64 INT16478 Positive_regulation of Plg 29 0.45 18.07 4.07
65 INT139898 Negative_regulation of Positive_regulation of Akt1 15 0.42 4.66 4.06
66 INT17324 Negative_regulation of Plg 26 0.38 13.5 4.05
67 INT133244 Regulation of Positive_regulation of Mapk1 11 0.43 3.52 4.03
68 INT113924 Binding of Mapk1 27 0.38 8.64 3.84
69 INT132223 Negative_regulation of Negative_regulation of Akt1 6 0.42 2.75 3.66
70 INT136692 Localization of Akt1 12 0.78 2.14 3.65
71 INT16644 Positive_regulation of Plg 16 0.60 6.38 3.62
72 INT25344 Localization of Plg 10 0.57 5 3.27
73 INT157687 Regulation of Gene_expression of Akt1 9 0.62 4.96 3.27
74 INT16390 Regulation of Plg 13 0.48 6.72 3.2
75 INT171368 Regulation of Phosphorylation of Mapk1 14 0.61 4.77 3.14
76 INT117720 Negative_regulation of Gene_expression of Akt1 11 0.37 2.33 3.08
77 INT188047 Positive_regulation of Wnt2 51 0.58 31.41 2.94
78 INT200895 Localization of Mapk1 6 0.67 2.08 2.82
79 INT117715 Regulation of Phosphorylation of Akt1 15 0.51 3.23 2.78
80 INT169112 Negative_regulation of Positive_regulation of Mapk1 9 0.59 1.84 2.78
81 INT145821 Negative_regulation of Gene_expression of Mapk1 16 0.41 8.05 2.77
82 INT152927 Negative_regulation of Mapk1 16 0.41 5.85 2.73
83 INT7978 Positive_regulation of Nsdhl 9 0.43 5.6 2.63
84 INT214355 Binding of Akt1 13 0.36 3.72 2.59
85 INT186116 Regulation of Gene_expression of MAPK1 9 0.44 5.85 2.32
86 INT138286 Regulation of Positive_regulation of Akt1 13 0.45 4.93 2.22
87 INT170482 Regulation of Gene_expression of Mapk1 5 0.43 5.73 2.1
88 INT109906 Localization of MAPK1 12 0.54 1.68 2.01
89 INT83709 Negative_regulation of Gene_expression of MAPK1 12 0.41 6.57 2.01
90 INT59283 Positive_regulation of Gene_expression of Plg 6 0.25 2.36 1.97
91 INT17326 Binding of Plg 14 0.43 11.72 1.94
92 INT142236 Regulation of Phosphorylation of Akt1 13 0.61 5.02 1.75
93 INT165332 Negative_regulation of Negative_regulation of Akt1 5 0.42 3.27 1.7
94 INT169461 Regulation of Gene_expression of Mapk1 7 0.44 1.64 1.61
95 INT117714 Regulation of Positive_regulation of Akt1 3 0.61 0.44 1.61
96 INT130019 Regulation of Phosphorylation of MAPK1 6 0.49 3.6 1.5
97 INT190646 Regulation of Regulation of Mapk1 1 0.30 1.16 1.43
98 INT16388 Protein_catabolism of Plg 6 0.79 3.46 1.4
99 INT153627 Binding of Mapk1 5 0.36 2.88 1.4
100 INT242153 Negative_regulation of Wnt2 19 0.49 11.87 1.37
101 INT17325 Negative_regulation of Protein_catabolism of Plg 1 0.32 0 1.37
102 INT104027 Negative_regulation of Negative_regulation of MAPK1 6 0.56 2.87 1.35
103 INT41381 Positive_regulation of Gene_expression of Plg 8 0.44 3.29 1.3
104 INT18422 Regulation of Plg 6 0.45 1.71 1.22
105 INT9477 Regulation of Gene_expression of Junb 5 0.45 0.88 1.15
106 INT207203 Transcription of Akt1 6 0.67 3.73 1.1
107 INT58174 Gene_expression of Junb 9 0.78 1.38 1.09
108 INT191050 Positive_regulation of Negative_regulation of Akt1 6 0.31 1.82 1.03
109 INT124374 Binding of Wnt2 21 0.31 10.16 0.99
110 INT61030 Negative_regulation of Positive_regulation of Junb 2 0.41 0.93 0.95
111 INT134660 Positive_regulation of Localization of Akt1 10 0.32 6.33 0.94
112 INT163508 Regulation of Gene_expression of Akt1 3 0.45 1.65 0.92
113 INT242152 Transcription of Wnt2 8 0.57 5.22 0.88
114 INT52232 Positive_regulation of Positive_regulation of Junb 4 0.47 0.45 0.88
115 INT30926 Regulation of Gene_expression of Plg 11 0.45 2.14 0.78
116 INT194780 Regulation of Negative_regulation of MAPK1 3 0.32 3.42 0.76
117 INT186941 Localization of Nsdhl 2 0.46 2.7 0.74
118 INT151170 Regulation of Regulation of Akt1 2 0.45 3.28 0.73
119 INT53977 Transcription of Junb 2 0.67 0.17 0.7
120 INT53980 Positive_regulation of Transcription of Junb 2 0.48 0.17 0.7
121 INT13702 Protein_catabolism of Plg 4 0.12 0.88 0.69
122 INT207204 Regulation of Transcription of Akt1 3 0.35 1.41 0.66
123 INT87265 Negative_regulation of Gene_expression of Junb 1 0.21 0 0.65
124 INT281466 Negative_regulation of Regulation of Akt1 1 0.33 0.31 0.63
125 INT53976 Regulation of Transcription of Junb 1 0.44 0 0.62
126 INT124373 Positive_regulation of Gene_expression of Wnt2 14 0.42 8.28 0.6
127 INT71671 Positive_regulation of Junb 5 0.70 0.6 0.6
128 INT125565 Gene_expression of Ncoa6 3 0.75 10.15 0.59
129 INT75524 Positive_regulation of Regulation of MAPK1 1 0.43 1.12 0.59
130 INT213503 Regulation of Wnt2 9 0.37 3.54 0.56
131 INT46340 Positive_regulation of Negative_regulation of Plg 2 0.15 1.71 0.54
132 INT190645 Positive_regulation of Negative_regulation of Mapk1 1 0.44 0.39 0.54
133 INT170475 Negative_regulation of Gene_expression of Mapk1 7 0.41 2.44 0.53
134 INT47703 Negative_regulation of Junb 4 0.51 0 0.53
135 INT218900 Regulation of Negative_regulation of Akt1 3 0.15 1.73 0.53
136 INT67242 Localization of Ncoa6 6 0.72 2.21 0.52
137 INT158440 Negative_regulation of Nsdhl 4 0.21 3.22 0.51
138 INT276189 Regulation of Localization of Akt1 1 0.43 0.2 0.5
139 INT96864 Localization of Plg 7 0.67 2.07 0.48
140 INT109911 Positive_regulation of Localization of MAPK1 4 0.33 0.56 0.48
141 INT125559 Positive_regulation of Ncoa6 7 0.59 3.98 0.47
142 INT201524 Localization of Wnt2 14 0.62 9.24 0.46
143 INT159151 Negative_regulation of Negative_regulation of Mapk1 1 0.32 0.38 0.45
144 INT188050 Regulation of Gene_expression of Wnt2 9 0.37 3.13 0.44
145 INT158577 Negative_regulation of Gene_expression of Plg 7 0.17 3.36 0.43
146 INT125566 Binding of Ncoa6 2 0.47 5.64 0.43
147 INT256628 Regulation of Nsdhl 2 0.11 4.12 0.43
148 INT261353 Negative_regulation of Gene_expression of Nsdhl 1 0.17 0.71 0.43
149 INT53979 Regulation of Regulation of Junb 1 0.44 0 0.41
150 INT7979 Binding of Nsdhl 6 0.30 3.71 0.4
151 INT39640 Negative_regulation of Gene_expression of Plg 2 0.25 1.13 0.39
152 INT274923 Protein_catabolism of Mapk1 1 0.47 0 0.39
153 INT274911 Positive_regulation of Protein_catabolism of Mapk1 1 0.27 0 0.39
154 INT92242 Binding of Plg 2 0.32 1.09 0.37
155 INT71669 Positive_regulation of Gene_expression of Junb 2 0.50 0.38 0.36
156 INT96865 Regulation of Positive_regulation of Plg 1 0.01 0.05 0.36
157 INT121782 Transcription of Mapk1 3 0.50 1.58 0.35
158 INT242156 Positive_regulation of Transcription of Wnt2 2 0.42 0.23 0.34
159 INT186939 Positive_regulation of Positive_regulation of Nsdhl 2 0.31 0.86 0.34
160 INT109907 Protein_catabolism of MAPK1 2 0.58 1.82 0.34
161 INT242149 Negative_regulation of Transcription of Wnt2 2 0.35 1.8 0.33
162 INT130113 Regulation of Regulation of MAPK1 1 0.22 0.16 0.33
163 INT321348 Positive_regulation of Localization of Akt1 1 0.30 0.08 0.32
164 INT242150 Positive_regulation of Positive_regulation of Wnt2 1 0.42 0.65 0.31
165 INT242154 Negative_regulation of Gene_expression of Wnt2 2 0.35 0.89 0.3
166 INT239464 Regulation of Negative_regulation of Akt1 3 0.31 0.37 0.25
167 INT125562 Positive_regulation of Gene_expression of Ncoa6 2 0.67 4.05 0.24
168 INT109931 Positive_regulation of Protein_catabolism of MAPK1 1 0.33 0.14 0.24
169 INT194801 Binding of MAPK1 7 0.29 1.9 0.23
170 INT71670 Regulation of Junb 2 0.27 0.17 0.23
171 INT153877 Positive_regulation of Binding of Plg 1 0.44 0.41 0.23
172 INT164149 Negative_regulation of Localization of Mapk1 3 0.33 1.32 0.22
173 INT216887 Positive_regulation of Localization of Plg 1 0.04 0.13 0.22
174 INT200898 Positive_regulation of Localization of Mapk1 1 0.30 0 0.22
175 INT261680 Positive_regulation of Negative_regulation of MAPK1 2 0.33 1.2 0.21
176 INT230483 Protein_catabolism of Akt1 2 0.10 1.11 0.2
177 INT352553 Negative_regulation of Binding of Wnt2 1 0.03 0.49 0.2
178 INT25345 Negative_regulation of Localization of Plg 1 0.08 0.81 0.19
179 INT178411 Regulation of Negative_regulation of Mapk1 1 0.44 0.94 0.19
180 INT268392 Regulation of Positive_regulation of Wnt2 2 0.09 0.87 0.18
181 INT276192 Transcription of Akt1 1 0.66 0.47 0.18
182 INT45721 Transcription of Plg 1 0.20 0.16 0.18
183 INT71667 Regulation of Positive_regulation of Junb 1 0.45 0.07 0.18
184 INT136871 Positive_regulation of Localization of Ncoa6 1 0.47 0.08 0.18
185 INT356268 Regulation of Localization of Mapk1 1 0.04 0.35 0.17
186 INT71668 Positive_regulation of Transcription of Junb 1 0.47 0.08 0.16
187 INT71666 Transcription of Junb 1 0.53 0.08 0.16
188 INT190389 Transcription of MAPK1 2 0.44 2.58 0.15
189 INT226185 Protein_catabolism of Akt1 7 0.53 2.43 0.14
190 INT39633 Negative_regulation of Positive_regulation of Plg 2 0.22 0.4 0.14
191 INT167723 Positive_regulation of Localization of Mapk1 2 0.10 0.76 0.13
192 INT206915 Regulation of Gene_expression of Nsdhl 2 0.22 1 0.13
193 INT236920 Positive_regulation of Binding of Mapk1 2 0.39 0.71 0.12
194 INT214360 Negative_regulation of Binding of Akt1 2 0.41 0.09 0.12
195 INT355216 Positive_regulation of Binding of Akt1 1 0.37 0.35 0.12
196 INT199082 Positive_regulation of Binding of Akt1 4 0.17 1.25 0.11
197 INT242157 Regulation of Localization of Wnt2 3 0.37 1.08 0.11
198 INT216835 Positive_regulation of Localization of Plg 1 0.03 0.27 0.11
199 INT200599 Positive_regulation of Positive_regulation of Plg 3 0.07 2.11 0.1
200 INT225342 Negative_regulation of Ncoa6 1 0.49 1.75 0.1
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