GO:0060736

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Name prostate gland growth
Categary Process
Go Slim No
Go Link GO:0060736
Unique Molecular Interactions 482
Total Molecular Interactions 670
Total Single Events 6107
Pain Genes Associated 17

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for prostate gland growth. They are ordered first by their pain relevance and then by number of times they were reported for prostate gland growth. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT142177 Calca Positive_regulation of Gene_expression of Igf1 8 0.78 3.57 5.71
2 INT42728 Binding of PRLR and Cpe 1 0.00 0 2.91
3 INT145826 Calca Positive_regulation of Gene_expression of Igf1 3 0.75 3.05 1.66
4 INT131185 PTH Positive_regulation of Gene_expression of IGF1 3 0.44 3.31 1.31
5 INT131184 PTGER2 Positive_regulation of Gene_expression of IGF1 1 0.63 2.47 1.29
6 INT106345 Igf1 Regulation of Localization of Acot1 1 0.06 0 1.02
7 INT12141 Igf1 Negative_regulation of Chat 1 0.32 0.63 1
8 INT140653 IGF1 Negative_regulation of Protein_catabolism of PARP1 1 0.32 0.63 0.98
9 INT140652 IGF1 Positive_regulation of Phosphorylation of MAPK1 1 0.26 0.63 0.98
10 INT320120 MTX1 Positive_regulation of PTEN 1 0.04 0.09 0.82
11 INT228255 Binding of Akt1 and Pten 2 0.43 1.78 0.8
12 INT137699 AR Regulation of PDYN 1 0.46 0.93 0.75
13 INT276213 Pten Regulation of Phosphorylation of Akt1 1 0.51 0.61 0.72
14 INT28947 GH1 Positive_regulation of Gene_expression of IGF1 4 0.22 3.78 0.69
15 INT34772 GH1 Regulation of IGF1 2 0.32 0.95 0.69
16 INT220148 Binding of IGF1 and IGFBP3 12 0.36 5.56 0.66
17 INT45369 IGF1 Regulation of GH1 1 0.04 1.12 0.65
18 INT261828 Igf1 Regulation of Localization of Trpv2 1 0.02 1.04 0.58
19 INT156668 Gh Positive_regulation of Igf1 5 0.22 2.07 0.57
20 INT317639 Igf1 Regulation of Creb1 1 0.23 0.16 0.57
21 INT192291 OR5A1 Positive_regulation of Gene_expression of IGF1 1 0.02 0.93 0.57
22 INT156667 Gh Positive_regulation of Gene_expression of Igf1 6 0.28 0.88 0.56
23 INT150291 Grk1 Positive_regulation of Gene_expression of Igf1 1 0.16 0.98 0.55
24 INT106347 Igf1 Regulation of Chat 1 0.44 0 0.55
25 INT142882 IGF1 Positive_regulation of Gene_expression of TRPV1 1 0.06 0.57 0.52
26 INT320121 Binding of PTEN and TNF 1 0.05 0.76 0.49
27 INT108568 Calca Positive_regulation of Igf1 1 0.51 0.08 0.48
28 INT185917 Binding of AR and MAPK1 1 0.07 0.5 0.47
29 INT276218 Binding of Akt1 and Pten 1 0.26 0.08 0.46
30 INT151890 Binding of PRLR and Adarb1 1 0.00 0 0.45
31 INT252425 Positive_regulation of AR Positive_regulation of Gene_expression of CXCL10 1 0.00 0.9 0.44
32 INT264295 Binding of DMD and IGF1 1 0.07 1.38 0.44
33 INT160046 INPPL1 Regulation of Gene_expression of PTEN 1 0.41 0.6 0.42
34 INT160047 PTEN Regulation of Gene_expression of AKT1 1 0.33 0.6 0.42
35 INT160049 PTEN Regulation of Gene_expression of INPPL1 1 0.41 0.6 0.42
36 INT221085 GHRH Positive_regulation of Gene_expression of IGF1 2 0.56 1.47 0.41
37 INT303655 Positive_regulation of Binding of IGF1 and SSTR1 1 0.16 2.19 0.41
38 INT139047 Negative_regulation of AR Negative_regulation of Positive_regulation of CPOX 1 0.07 0.76 0.4
39 INT303650 Binding of IGF1 and SSTR1 1 0.12 2.17 0.4
40 INT99304 Igf1 Positive_regulation of Gh1 1 0.44 0.39 0.39
41 INT182492 IL1B Regulation of Gene_expression of IGF1 1 0.01 0.83 0.38
42 INT78444 Binding of GH1 and IGF1 4 0.16 2.82 0.37
43 INT316545 Binding of IGF1 and SST 1 0.06 0.45 0.37
44 INT272951 Binding of TNF and Igf1 1 0.14 1.48 0.36
45 INT272953 Negative_regulation of Binding of TNF and Igf1 1 0.16 1.48 0.36
46 INT63278 Gpm6a Regulation of Igf1 1 0.01 0 0.36
47 INT272952 Igf1 Positive_regulation of Localization of TNF 1 0.19 1.53 0.35
48 INT257741 HRAS Negative_regulation of PTEN 1 0.15 1.06 0.35
49 INT187064 ARSD Negative_regulation of CYP19A1 1 0.22 0.7 0.35
50 INT252453 Binding of AR and Adora2b 1 0.05 0 0.35
51 INT257737 Positive_regulation of HRAS Negative_regulation of PTEN 1 0.17 1.07 0.35
52 INT277656 Igf1 Positive_regulation of Igfbp3 1 0.01 0.4 0.34
53 INT75641 AR Positive_regulation of Positive_regulation of EIF2B3 1 0.02 0 0.33
54 INT175330 IL6 Positive_regulation of Gene_expression of CYP19A1 1 0.01 0.97 0.32
55 INT349664 PYCARD Negative_regulation of Localization of AR 1 0.05 0 0.32
56 INT349662 Binding of PYCARD and Negative_regulation of Localization of AR 1 0.05 0 0.32
57 INT222299 Binding of CYP19A1 and AIS 2 0.25 1.65 0.31
58 INT62616 Regulation of Binding of PRLR and ST14 1 0.00 0 0.31
59 INT62615 Binding of PRLR and ST14 1 0.00 0 0.31
60 INT242399 Cyp19a1 Negative_regulation of Gene_expression of Bad 1 0.00 1.32 0.31
61 INT173947 Il6 Positive_regulation of Gene_expression of IGF1 1 0.05 1.02 0.31
62 INT65268 Igf1 Positive_regulation of Col7a1 1 0.48 0 0.3
63 INT242398 Cyp19a1 Positive_regulation of Bcl2 1 0.00 1.28 0.3
64 INT51275 IGF1 Negative_regulation of INS 2 0.35 0.98 0.29
65 INT323653 Binding of Igf1 and Igfbp1 1 0.20 1.14 0.29
66 INT142885 Positive_regulation of IGF1 Positive_regulation of TRPV1 1 0.04 0.24 0.29
67 INT134927 CYP19A1 Positive_regulation of Gene_expression of MME 1 0.30 1.04 0.28
68 INT177476 Gnrhr Positive_regulation of Localization of Igf1 1 0.05 1.01 0.28
69 INT134930 MME Positive_regulation of Gene_expression of CYP19A1 1 0.30 1.04 0.28
70 INT177478 Gnrhr Positive_regulation of Localization of IGF1 1 0.04 1.01 0.28
71 INT173949 Binding of IGF1 and Atp6v1e1 1 0.01 0.89 0.28
72 INT142884 IGF1 Positive_regulation of TRPV1 1 0.04 0.24 0.28
73 INT50303 Igf1 Regulation of Localization of Gnrhr 1 0.05 0.09 0.27
74 INT282501 Negative_regulation of Cyp19a1 Negative_regulation of Gene_expression of Aaiq4 1 0.01 0.6 0.27
75 INT68872 Ghrh Regulation of IGF1 1 0.09 0.18 0.26
76 INT223042 AR Positive_regulation of ADCY1 1 0.01 0.41 0.25
77 INT199970 CYP19A1 Positive_regulation of Gene_expression of ESR1 1 0.06 0.72 0.25
78 INT97188 Gh Positive_regulation of Localization of Igf1 1 0.02 0.54 0.25
79 INT257776 Phosphorylation of AR Positive_regulation of Localization of TAB2 1 0.26 0.38 0.24
80 INT252427 IGKV2D-29 Regulation of Gene_expression of AR 1 0.02 0 0.24
81 INT139046 Negative_regulation of AR Negative_regulation of Phosphorylation of DYT10 1 0.33 0.34 0.23
82 INT139050 Negative_regulation of AR Negative_regulation of Phosphorylation of PRKCB 1 0.02 0.34 0.23
83 INT139045 Negative_regulation of AR Negative_regulation of CPOX 1 0.07 0.34 0.23
84 INT139048 Negative_regulation of AR Negative_regulation of Positive_regulation of TRAF3IP2 1 0.02 0.34 0.23
85 INT7869 Gh Negative_regulation of IGF1 1 0.39 0.47 0.23
86 INT139049 Negative_regulation of AR Negative_regulation of Positive_regulation of DYT10 1 0.33 0.34 0.23
87 INT245590 Ghr Positive_regulation of Gene_expression of Igf1 1 0.34 0.61 0.23
88 INT265886 IGF1 Positive_regulation of AKT1 1 0.11 3.06 0.23
89 INT25907 Binding of PRLR and Cish 1 0.00 0 0.23
90 INT151884 Binding of PRLR and YY1 1 0.01 0 0.23
91 INT220383 Binding of Igf1 and Cotl1 1 0.03 0.37 0.22
92 INT311613 Binding of Slc6a4 and Pten 1 0.24 0.32 0.21
93 INT173946 Igf1 Regulation of Gene_expression of IGF1 1 0.08 0.68 0.21
94 INT173944 IGF1 Regulation of Gene_expression of Igf1 1 0.08 0.68 0.21
95 INT173945 Hrt1 Positive_regulation of Positive_regulation of IGF1 1 0.01 0.32 0.21
96 INT286070 Igf1 Regulation of Regulation of Ins1 1 0.10 1.7 0.2
97 INT203848 Binding of Pten and Lna1 1 0.06 0.4 0.2
98 INT106825 Ednra Negative_regulation of Igf1 1 0.07 0.07 0.2
99 INT286071 Igf1 Regulation of Ins1 1 0.10 1.69 0.2
100 INT145140 Negative_regulation of CPOX Negative_regulation of Gene_expression of CYP19A1 1 0.13 0.47 0.2
101 INT250537 Ptpn6 Negative_regulation of Igf1 1 0.08 0 0.2
102 INT220146 Binding of IGF1 and IGFBP1 2 0.10 1.57 0.19
103 INT68510 Binding of ATM and PRLR 1 0.01 0 0.19
104 INT224688 Pten Regulation of Akt1 1 0.04 1.12 0.19
105 INT281477 Binding of Pten and Th 1 0.28 0.4 0.19
106 INT173943 Binding of IGF1 and Il6 1 0.04 0.11 0.19
107 INT224680 Tgfb1 Negative_regulation of Pten 1 0.00 1.19 0.18
108 INT198382 Binding of AR and SRD5A1 2 0.06 0.84 0.17
109 INT231033 Igf1 Positive_regulation of Sec22b 1 0.06 0 0.17
110 INT175991 Binding of VEGFA and Igf1 1 0.04 0.57 0.17
111 INT220387 Gh1 Regulation of Localization of Igf1 1 0.05 0.3 0.17
112 INT265892 IGF1 Positive_regulation of PIK3CG 1 0.18 1.96 0.16
113 INT59952 Gh Positive_regulation of IGF1 1 0.46 0.84 0.16
114 INT269758 Negative_regulation of IGF1 Negative_regulation of Positive_regulation of IGFBP2 1 0.10 2.15 0.16
115 INT122361 Binding of AR and OPRM1 1 0.26 0.14 0.16
116 INT73076 IGF1 Positive_regulation of GH1 4 0.45 0.99 0.15
117 INT334634 Binding of Igf1 and Igf1r 1 0.14 0.45 0.15
118 INT185515 Binding of Igf1 and Csf2 1 0.29 0.4 0.15
119 INT208264 Park7 Negative_regulation of Pten 1 0.16 1.16 0.15
120 INT122362 AR Positive_regulation of Positive_regulation of OPRM1 1 0.32 0.19 0.14
121 INT50302 Igf1 Regulation of Gh1 1 0.22 0 0.14
122 INT225778 Igf1 Negative_regulation of Positive_regulation of Ppi-rs 1 0.01 0.82 0.14
123 INT220385 Binding of Igf1 and Gnrhr 1 0.05 0.99 0.14
124 INT220386 Binding of Gh1 and Igf1 1 0.07 0.99 0.14
125 INT65272 Igf1 Positive_regulation of Binding of Col7a1 1 0.42 0 0.14
126 INT45371 IGF1 Regulation of Smc1b 1 0.08 0 0.14
127 INT303600 IGF1 Regulation of Gene_expression of GH1 1 0.39 0.83 0.14
128 INT65269 Igf1 Positive_regulation of Gene_expression of Lox 1 0.15 0 0.14
129 INT298715 Igf1 Positive_regulation of Gene_expression of PDGFA 1 0.00 0.22 0.14
130 INT45370 IGF1 Regulation of Gh1 1 0.13 0 0.14
131 INT68753 IGF1 Regulation of Gene_expression of Gh 2 0.02 0.68 0.13
132 INT253009 Igf1 Regulation of PTTG1 1 0.03 0.44 0.13
133 INT215034 Gh Regulation of Igf1 1 0.13 0.27 0.13
134 INT220147 IGFBP3 Positive_regulation of IGF1 1 0.10 0.53 0.13
135 INT209645 AR Regulation of STUB1 1 0.04 0.93 0.13
136 INT65267 Igf1 Regulation of Gene_expression of Plod3 1 0.07 0 0.13
137 INT251115 Positive_regulation of Binding of AR and Ctnnb1 1 0.01 1.02 0.13
138 INT65271 Igf1 Positive_regulation of Gene_expression of Plod3 1 0.12 0 0.13
139 INT169128 Trove2 Negative_regulation of Gene_expression of AR 1 0.05 0.94 0.13
140 INT223040 AR Positive_regulation of Negative_regulation of TFPI 1 0.03 0 0.13
141 INT228453 Igf1 Positive_regulation of Prkca 2 0.12 1.17 0.12
142 INT354620 AR Positive_regulation of Hspg2 1 0.00 0 0.12
143 INT228456 Igf1 Positive_regulation of Trpv1 1 0.24 0.97 0.12
144 INT251114 Binding of AR and Ctnnb1 1 0.01 1 0.12
145 INT207551 IGF1 Positive_regulation of Gene_expression of GH1 2 0.22 1.18 0.11
146 INT308651 Binding of Igf1 and Ins1 1 0.02 0.22 0.11
147 INT175985 Igf1 Positive_regulation of Gene_expression of Serpina1c 1 0.14 0.55 0.11
148 INT256544 Pten Negative_regulation of Akt1 1 0.05 1.07 0.11
149 INT323871 LEP Regulation of Gene_expression of IGF1 1 0.14 1.19 0.11
150 INT328143 Gabrb3 Positive_regulation of Ube3a 1 0.56 0.99 0.11
151 INT50301 Igf1 Positive_regulation of Regulation of Gh1 1 0.24 0 0.11
152 INT222507 Igf1 Positive_regulation of Localization of Edn3 1 0.05 0 0.11
153 INT175987 Igf1 Positive_regulation of Serpina1c 1 0.13 0.54 0.11
154 INT50300 Igf1 Positive_regulation of Gene_expression of Ghrh 1 0.26 0 0.11
155 INT185918 AR Positive_regulation of Gene_expression of NOS2 1 0.12 0.21 0.11
156 INT323875 Binding of BMI1 and IGF1 1 0.01 1.2 0.11
157 INT51720 Negative_regulation of Ins1 Negative_regulation of Igf1 1 0.12 0.85 0.11
158 INT256545 Positive_regulation of Pten Negative_regulation of Akt1 1 0.05 1.07 0.11
159 INT328146 Gabrb3 Negative_regulation of Ube3a 1 0.48 0.99 0.11
160 INT173948 Gh Positive_regulation of Gene_expression of IGF1 2 0.36 0.77 0.1
161 INT220149 Binding of IGF1 and IGFALS 2 0.39 0.44 0.1
162 INT267124 IGF1 Negative_regulation of Gene_expression of INS 2 0.14 0.18 0.1
163 INT277657 Igfbp1 Negative_regulation of Negative_regulation of Igf1 1 0.02 0.26 0.1
164 INT161741 Gh1 Positive_regulation of Gene_expression of Igf1 1 0.35 0.55 0.1
165 INT42067 Rln1 Positive_regulation of Phosphorylation of Myo1f 1 0.11 0.1 0.1
166 INT137368 Retn Positive_regulation of Gene_expression of IGF1 1 0.00 0.17 0.1
167 INT220743 Binding of AR and EGFR 1 0.01 0.46 0.1
168 INT25501 Gnrhr Positive_regulation of Igf1 1 0.12 0.09 0.1
169 INT161742 Gnrhr Positive_regulation of Gene_expression of Igf1 1 0.25 0.55 0.1
170 INT190684 Binding of A2M and IGF1 1 0.16 1.54 0.1
171 INT316543 GH1 Regulation of Gene_expression of IGF1 1 0.03 1.32 0.09
172 INT220394 MRXS5 Positive_regulation of Gene_expression of CYP19A1 1 0.00 0.89 0.09
173 INT265887 IGF1 Negative_regulation of BCL2 1 0.09 1.02 0.09
174 INT133481 TNF Positive_regulation of Phosphorylation of PTEN 1 0.13 0.61 0.09
175 INT340555 Igf1 Positive_regulation of Mapk1 1 0.24 0.65 0.09
176 INT285070 CCL16 Positive_regulation of Gene_expression of CYP19A1 1 0.02 0.69 0.09
177 INT220412 Cpox Positive_regulation of Gene_expression of CYP19A1 1 0.01 0.9 0.09
178 INT276141 Binding of Gh and Igf1 2 0.34 0.66 0.08
179 INT49363 Gh Positive_regulation of Igf1 1 0.00 0.49 0.08
180 INT192293 Binding of IGF1 and IL1B 1 0.15 0.08 0.08
181 INT224985 Binding of Ube3a and Snord116 1 0.34 0.45 0.08
182 INT175984 Igf1 Regulation of Localization of Serpina1c 1 0.14 0.54 0.08
183 INT178434 Il6 Positive_regulation of Ar 1 0.01 0.93 0.08
184 INT257777 INCENP Positive_regulation of AR 1 0.04 0.49 0.08
185 INT9497 Gh Positive_regulation of Gene_expression of Igf1 1 0.08 0.31 0.08
186 INT325058 Igf1 Positive_regulation of Ang 1 0.04 1.4 0.08
187 INT312219 Binding of IGF1 and IGFBP5 1 0.02 0.13 0.08
188 INT261262 AIS Negative_regulation of Cyp19a1 1 0.01 0.2 0.08
189 INT213933 AR Negative_regulation of Cyp19a1 1 0.07 0.79 0.07
190 INT27374 Rln1 Regulation of Oxt 1 0.06 0.13 0.07
191 INT328150 H2-Q13 Positive_regulation of Gene_expression of Ube3a 1 0.55 1.23 0.07
192 INT323872 LEP Positive_regulation of Gene_expression of IGF1 1 0.35 0.77 0.07
193 INT265883 IGF1 Positive_regulation of Transcription of FOXO1 1 0.17 1.14 0.07
194 INT70762 IGF1 Regulation of Gh 1 0.00 0.17 0.07
195 INT265882 IGF1 Positive_regulation of Transcription of AKT1 1 0.08 1.13 0.07
196 INT224293 AR Positive_regulation of Protein_catabolism of ESR1 1 0.24 0.4 0.07
197 INT328380 AR Negative_regulation of Gene_expression of Ghrl 1 0.01 0.55 0.07
198 INT328148 H2-Q13 Positive_regulation of Ube3a 1 0.55 1.23 0.07
199 INT42066 Rln1 Regulation of Phosphorylation of Myo1f 1 0.05 0.07 0.07
200 INT293813 ERBB2 Positive_regulation of Positive_regulation of AR 1 0.09 0.45 0.07

Single Events

The table below shows the top 100 pain related interactions that have been reported for prostate gland growth. They are ordered first by their pain relevance and then by number of times they were reported in prostate gland growth. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07
2 INT14559 Gene_expression of Igf1 254 0.78 112 34.17
3 INT8915 Gene_expression of Igf1 199 0.78 78.58 32.51
4 INT5206 Gene_expression of AR 316 0.78 113.83 27.29
5 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36
6 INT14556 Positive_regulation of Igf1 105 0.69 52.21 24.04
7 INT71047 Gene_expression of CYP19A1 122 0.78 68.78 22.21
8 INT85952 Positive_regulation of AR 168 0.67 64.36 20.66
9 INT28951 Negative_regulation of IGF1 133 0.59 75.77 18.9
10 INT14724 Negative_regulation of CYP19A1 233 0.59 96.56 18.26
11 INT28950 Positive_regulation of Gene_expression of IGF1 99 0.69 46.9 16.47
12 INT65263 Positive_regulation of Gene_expression of Igf1 61 0.69 25.69 14.49
13 INT17539 Positive_regulation of Igf1 68 0.69 28.47 13.02
14 INT28952 Negative_regulation of Gene_expression of IGF1 75 0.58 41.11 12.32
15 INT151168 Gene_expression of Pten 60 0.78 35.63 10.54
16 INT11729 Regulation of IGF1 71 0.61 44.58 9.71
17 INT12367 Binding of PRLR 17 0.03 2.05 9.69
18 INT10597 Gene_expression of Cyp19a1 27 0.78 7.48 9.11
19 INT35366 Binding of AR 87 0.47 30.52 8.9
20 INT34777 Localization of IGF1 82 0.80 42.68 8.62
21 INT119831 Gene_expression of PTEN 55 0.75 40.37 8.57
22 INT119904 Regulation of CYP19A1 25 0.62 9.36 8.34
23 INT3803 Negative_regulation of Igf1 45 0.58 15.95 7.98
24 INT142344 Transcription of Igf1 22 0.69 7.55 6.77
25 INT50387 Negative_regulation of AR 67 0.45 26.31 6.61
26 INT14560 Regulation of Igf1 41 0.59 19.59 6.3
27 INT9494 Positive_regulation of Gene_expression of Igf1 34 0.67 17.77 6.26
28 INT9495 Negative_regulation of Gene_expression of Igf1 31 0.59 11.87 6.1
29 INT9321 Transcription of Igf1 25 0.69 10.2 6.08
30 INT8916 Regulation of Igf1 45 0.60 13.06 5.81
31 INT135760 Regulation of Gene_expression of Cyp19a1 2 0.62 1.15 5.81
32 INT151032 Localization of Igf1 49 0.76 26.32 5.71
33 INT23010 Positive_regulation of CYP19A1 28 0.58 24.18 5.37
34 INT99091 Regulation of AR 70 0.45 31.68 5.05
35 INT13313 Regulation of PRLR 7 0.07 1.65 4.77
36 INT5205 Localization of AR 43 0.80 12.87 4.63
37 INT84727 Negative_regulation of Gene_expression of AR 38 0.58 12.46 4.63
38 INT14557 Negative_regulation of Igf1 96 0.59 54.83 4.45
39 INT49360 Localization of Igf1 22 0.76 6.96 4.26
40 INT276198 Positive_regulation of Pten 1 0.52 5.02 3.88
41 INT142174 Regulation of Gene_expression of Igf1 28 0.60 11.86 3.77
42 INT10824 Negative_regulation of Cyp19a1 38 0.57 25.18 3.56
43 INT151171 Positive_regulation of Pten 20 0.55 13.3 3.54
44 INT5204 Positive_regulation of Gene_expression of AR 60 0.67 23.54 3.53
45 INT18825 Gene_expression of PRLR 8 0.40 2 3.47
46 INT208291 Negative_regulation of Pten 2 0.44 5.42 3.36
47 INT105537 Regulation of Gene_expression of Igf1 15 0.58 6.97 3.23
48 INT192676 Binding of PTEN 14 0.46 10.58 3.06
49 INT131187 Regulation of Gene_expression of IGF1 18 0.62 11.18 3.05
50 INT116376 Transcription of Cyp19a1 2 0.40 0.74 3.04
51 INT20082 Positive_regulation of PRLR 6 0.29 4.27 3.03
52 INT133809 Negative_regulation of Gene_expression of CYP19A1 9 0.43 7.67 2.99
53 INT113277 Positive_regulation of Gene_expression of CYP19A1 13 0.69 10.23 2.97
54 INT16130 Binding of IGF1 67 0.48 27.43 2.95
55 INT184477 Negative_regulation of Pten 27 0.59 15.61 2.8
56 INT119383 Gene_expression of Pten 11 0.59 10.33 2.73
57 INT25646 Negative_regulation of PRLR 5 0.08 0.08 2.62
58 INT119838 Positive_regulation of PTEN 25 0.67 21.71 2.5
59 INT185927 Positive_regulation of Positive_regulation of AR 12 0.34 6.35 2.5
60 INT139735 Positive_regulation of Transcription of Igf1 4 0.53 1.93 2.49
61 INT66544 Binding of Igf1 23 0.46 8.33 2.44
62 INT34266 Negative_regulation of Binding of PRLR 3 0.01 0 2.35
63 INT71048 Transcription of CYP19A1 11 0.72 8.74 2.24
64 INT179885 Regulation of PTEN 8 0.26 11.88 2.18
65 INT111113 Binding of CYP19A1 15 0.36 9.17 2.12
66 INT224615 Negative_regulation of Gene_expression of Pten 7 0.59 2.99 2.09
67 INT342803 Positive_regulation of Transcription of Cyp19a1 1 0.30 0.33 2.08
68 INT276201 Phosphorylation of Pten 1 0.61 1.31 2.08
69 INT156666 Positive_regulation of Localization of Igf1 11 0.62 6.94 1.95
70 INT142341 Positive_regulation of Transcription of Igf1 8 0.49 2.44 1.95
71 INT81347 Regulation of Cyp19a1 7 0.40 2.1 1.94
72 INT132971 Negative_regulation of Localization of IGF1 5 0.42 3.98 1.94
73 INT84722 Regulation of Gene_expression of AR 20 0.61 7.73 1.69
74 INT224975 Gene_expression of Ube3a 5 0.76 7.18 1.69
75 INT66709 Transcription of IGF1 13 0.71 5.65 1.64
76 INT276171 Positive_regulation of Gene_expression of Pten 3 0.52 7.24 1.64
77 INT10596 Positive_regulation of Cyp19a1 10 0.42 2.08 1.62
78 INT10598 Gene_expression of Ar 10 0.64 3.44 1.61
79 INT15969 Negative_regulation of Ar 11 0.43 2.77 1.59
80 INT151169 Positive_regulation of Gene_expression of Pten 15 0.45 12.88 1.53
81 INT49361 Regulation of Positive_regulation of Igf1 2 0.45 2.15 1.49
82 INT228249 Binding of Pten 7 0.48 3.26 1.45
83 INT281470 Regulation of Gene_expression of Pten 4 0.39 1.13 1.42
84 INT135959 Negative_regulation of Gene_expression of Igf1 37 0.56 21.16 1.41
85 INT127889 Regulation of Gene_expression of CYP19A1 11 0.62 6.7 1.41
86 INT276196 Positive_regulation of Phosphorylation of Pten 1 0.38 0.19 1.41
87 INT304045 Transcription of PTEN 2 0.51 4.12 1.4
88 INT276181 Negative_regulation of Gene_expression of Pten 1 0.44 2.48 1.37
89 INT90491 Binding of Igf1 25 0.44 9.75 1.36
90 INT82932 Transcription of AR 14 0.67 5.75 1.34
91 INT68500 Regulation of Ar 6 0.27 4.16 1.32
92 INT213379 Phosphorylation of AR 6 0.63 2.03 1.21
93 INT190014 Regulation of Pten 8 0.62 6.03 1.2
94 INT119832 Positive_regulation of Gene_expression of PTEN 12 0.49 7.12 1.19
95 INT142616 Negative_regulation of Positive_regulation of Igf1 5 0.43 1.56 1.16
96 INT20080 Localization of PRLR 2 0.03 0.42 1.12
97 INT28949 Negative_regulation of Positive_regulation of IGF1 11 0.42 5.03 1.11
98 INT168395 Transcription of Cyp19a1 2 0.51 2.5 1.06
99 INT168397 Gene_expression of Cyp19a1 2 0.06 1.77 1.06
100 INT72129 Positive_regulation of Positive_regulation of IGF1 11 0.50 4.61 1.05
101 INT169407 Phosphorylation of IGF1 4 0.63 0.83 1.01
102 INT168398 Localization of Cyp19a1 1 0.08 0.89 0.97
103 INT209679 Positive_regulation of Regulation of AR 3 0.37 1.88 0.96
104 INT276177 Regulation of Gene_expression of Pten 1 0.34 1.51 0.84
105 INT202241 Positive_regulation of Negative_regulation of IGF1 5 0.48 1.56 0.82
106 INT224958 Negative_regulation of Transcription of Igf1 5 0.56 1.37 0.81
107 INT79344 Binding of Cyp19a1 4 0.33 0.61 0.8
108 INT156529 Positive_regulation of Gene_expression of Ar 1 0.05 0.09 0.8
109 INT119834 Phosphorylation of PTEN 12 0.79 6.78 0.75
110 INT185669 Positive_regulation of Localization of AR 7 0.33 1.83 0.73
111 INT161339 Localization of Cyp19a1 1 0.73 1.32 0.71
112 INT156060 Regulation of Binding of AR 2 0.09 0.42 0.69
113 INT276199 Binding of Pten 2 0.30 0.4 0.67
114 INT44478 Negative_regulation of PTEN 32 0.57 27.45 0.63
115 INT124211 Protein_catabolism of IGF1 2 1.00 1.29 0.63
116 INT276179 Regulation of Pten 1 0.46 0.81 0.63
117 INT17493 Binding of Ar 14 0.48 3.62 0.6
118 INT106343 Positive_regulation of Positive_regulation of Igf1 2 0.69 1.45 0.59
119 INT49343 Positive_regulation of Ar 8 0.42 4.38 0.58
120 INT171105 Positive_regulation of Positive_regulation of CYP19A1 5 0.39 4.02 0.58
121 INT161322 Localization of PTEN 9 0.73 5.65 0.57
122 INT220365 Negative_regulation of Transcription of Igf1 3 0.45 1.28 0.56
123 INT353896 Negative_regulation of Phosphorylation of Cyp19a1 1 0.22 0.47 0.55
124 INT353893 Phosphorylation of Cyp19a1 1 0.31 0.46 0.55
125 INT125578 Positive_regulation of Localization of IGF1 6 0.60 7.59 0.53
126 INT49362 Positive_regulation of Localization of Igf1 4 0.65 2.26 0.53
127 INT176146 Positive_regulation of Localization of PTEN 3 0.36 1.69 0.5
128 INT185513 Phosphorylation of Igf1 3 0.67 0.46 0.5
129 INT95375 Regulation of Transcription of PRLR 1 0.00 0 0.49
130 INT95377 Regulation of Gene_expression of PRLR 1 0.00 0 0.49
131 INT95376 Transcription of PRLR 1 0.00 0 0.49
132 INT137556 Negative_regulation of Cyp19a1 3 0.35 1.53 0.48
133 INT71046 Localization of CYP19A1 2 0.78 1.38 0.48
134 INT276174 Regulation of Negative_regulation of Pten 1 0.34 0.63 0.47
135 INT187717 Regulation of Negative_regulation of CYP19A1 11 0.42 2.85 0.45
136 INT127890 Positive_regulation of Negative_regulation of CYP19A1 6 0.50 1.41 0.45
137 INT140942 Regulation of Transcription of Igf1 3 0.32 1.37 0.43
138 INT9697 Positive_regulation of Rln1 2 0.49 0.31 0.43
139 INT276180 Positive_regulation of Negative_regulation of Pten 1 0.35 0.89 0.43
140 INT84915 Negative_regulation of Gene_expression of Cyp19a1 2 0.15 1.29 0.42
141 INT276202 Negative_regulation of Protein_catabolism of Pten 1 0.32 0.78 0.42
142 INT276204 Protein_catabolism of Pten 1 0.75 0.77 0.41
143 INT203816 Localization of Pten 4 0.75 1.37 0.4
144 INT38562 Localization of Rln1 2 0.73 0 0.4
145 INT104312 Positive_regulation of Transcription of AR 2 0.37 0.96 0.38
146 INT181122 Positive_regulation of Gene_expression of Cyp19a1 1 0.02 0.68 0.36
147 INT261774 Positive_regulation of Phosphorylation of Igf1 1 0.08 0.09 0.36
148 INT151167 Phosphorylation of Pten 3 0.72 1.69 0.35
149 INT151166 Positive_regulation of Phosphorylation of Pten 2 0.40 1.54 0.35
150 INT200198 Regulation of Localization of Igf1 6 0.58 4.51 0.34
151 INT209323 Positive_regulation of Transcription of CYP19A1 5 0.32 4.22 0.33
152 INT49672 Regulation of Negative_regulation of IGF1 1 0.21 1.07 0.33
153 INT105968 Positive_regulation of Binding of Igf1 2 0.20 0.56 0.32
154 INT281469 Transcription of Pten 2 0.72 1.12 0.32
155 INT281474 Regulation of Transcription of Pten 1 0.62 0.35 0.32
156 INT169405 Negative_regulation of Phosphorylation of IGF1 1 0.07 0.15 0.32
157 INT263819 Regulation of Gene_expression of PTEN 1 0.25 0.63 0.32
158 INT224979 Negative_regulation of Ube3a 2 0.57 3.18 0.29
159 INT17492 Negative_regulation of Binding of Ar 3 0.59 0.76 0.28
160 INT293387 Regulation of Localization of AR 1 0.05 0 0.28
161 INT266974 Protein_catabolism of AR 2 0.34 1.91 0.27
162 INT282487 Regulation of Negative_regulation of Cyp19a1 1 0.22 0.6 0.27
163 INT20081 Positive_regulation of Localization of PRLR 1 0.03 0.07 0.27
164 INT133488 Negative_regulation of Phosphorylation of PTEN 4 0.41 1.88 0.26
165 INT123520 Gene_expression of Ar 12 0.32 6.98 0.25
166 INT279628 Negative_regulation of Ar 5 0.04 6.1 0.25
167 INT185930 Regulation of Positive_regulation of AR 3 0.20 1.01 0.25
168 INT152667 Negative_regulation of Transcription of AR 3 0.42 0.72 0.24
169 INT112378 Negative_regulation of Regulation of Ar 1 0.43 0.19 0.23
170 INT200200 Positive_regulation of Negative_regulation of Igf1 3 0.47 2.33 0.22
171 INT265899 Regulation of Binding of IGF1 2 0.22 0.94 0.22
172 INT257784 Positive_regulation of Phosphorylation of AR 2 0.45 0.96 0.21
173 INT27373 Negative_regulation of Rln1 2 0.58 0.24 0.2
174 INT175360 Regulation of Transcription of CYP19A1 1 0.04 1 0.19
175 INT62617 Positive_regulation of Positive_regulation of PRLR 1 0.01 0 0.19
176 INT173753 Positive_regulation of Negative_regulation of Igf1 1 0.34 0.47 0.19
177 INT328135 Negative_regulation of Gene_expression of Ube3a 1 0.42 0.9 0.19
178 INT172368 Negative_regulation of Binding of IGF1 3 0.42 1.57 0.18
179 INT224616 Regulation of Negative_regulation of Pten 1 0.13 1.21 0.18
180 INT231055 Regulation of Localization of Igf1 1 0.15 0 0.17
181 INT198357 Negative_regulation of Localization of Igf1 1 0.03 0.51 0.17
182 INT183242 Negative_regulation of Gene_expression of PTEN 6 0.55 3.81 0.16
183 INT286068 Positive_regulation of Positive_regulation of Igf1 2 0.40 1.03 0.16
184 INT328136 Transcription of Ube3a 1 0.67 0 0.16
185 INT217993 Positive_regulation of Ube3a 1 0.41 0.62 0.16
186 INT49346 Transcription of Ar 3 0.63 0.8 0.14
187 INT123527 Negative_regulation of Gene_expression of Ar 2 0.10 0 0.14
188 INT185511 Regulation of Phosphorylation of Igf1 1 0.37 0 0.14
189 INT175970 Negative_regulation of Phosphorylation of Igf1 2 0.39 2.1 0.13
190 INT152669 Negative_regulation of Localization of AR 2 0.25 0.75 0.13
191 INT285632 Regulation of Binding of Igf1 1 0.37 0.55 0.13
192 INT185673 Negative_regulation of Negative_regulation of AR 3 0.28 1.12 0.12
193 INT243079 Regulation of Ar 3 0.08 1.22 0.12
194 INT239373 Positive_regulation of Positive_regulation of PTEN 3 0.25 4.98 0.12
195 INT212553 Negative_regulation of Transcription of IGF1 1 0.39 0.3 0.12
196 INT48615 Positive_regulation of Binding of IGF1 5 0.50 0.54 0.11
197 INT162432 Positive_regulation of Ar 3 0.23 2.34 0.11
198 INT127820 Regulation of Rln1 1 0.06 0.75 0.11
199 INT175968 Phosphorylation of Igf1 6 0.74 2.54 0.1
200 INT259063 Binding of UBE3A 2 0.36 1.15 0.09
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