GO:0060789

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Name hair follicle placode formation
Categary Process
Go Slim No
Go Link GO:0060789
Unique Molecular Interactions 77
Total Molecular Interactions 85
Total Single Events 605
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for hair follicle placode formation. They are ordered first by their pain relevance and then by number of times they were reported for hair follicle placode formation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT140922 Btnl2 Negative_regulation of EDA 1 0.00 0.88 0.8
2 INT27526 Binding of Sdcbp and Eda 1 0.13 0 0.65
3 INT343838 EDA Positive_regulation of TLR4 1 0.11 0.87 0.51
4 INT97949 Negative_regulation of NRP2 Negative_regulation of Positive_regulation of CDC42 1 0.06 0.72 0.51
5 INT97953 ST3GAL3 Positive_regulation of CDC42 1 0.09 0.7 0.5
6 INT300609 Binding of Ctnnb1 and Wnt2 1 0.02 0.25 0.37
7 INT124378 Prodh2 Positive_regulation of Ctnnb1 1 0.00 0.59 0.35
8 INT285567 Binding of IL1B and Cdc42 1 0.03 0.77 0.31
9 INT333918 HDAC1 Regulation of Trp53 1 0.03 1.24 0.3
10 INT343832 Positive_regulation of EDA Positive_regulation of TLR4 1 0.11 0.43 0.27
11 INT317773 Positive_regulation of GATA3 Positive_regulation of HDAC1 1 0.23 0.69 0.25
12 INT317775 GATA3 Positive_regulation of HDAC1 1 0.23 0.69 0.25
13 INT343864 EDA Positive_regulation of Gene_expression of TLR4 1 0.11 0.44 0.25
14 INT317771 GSR Positive_regulation of HDAC1 1 0.10 0.69 0.25
15 INT317776 Positive_regulation of GSR Positive_regulation of HDAC1 1 0.10 0.69 0.25
16 INT333892 TNF Positive_regulation of Gene_expression of HDAC1 1 0.09 0.46 0.23
17 INT292565 MAP3K5 Positive_regulation of Positive_regulation of CDC42 1 0.02 0 0.23
18 INT251115 Positive_regulation of Binding of AR and Ctnnb1 1 0.01 1.02 0.13
19 INT200326 Hdac1 Negative_regulation of Lhcgr 1 0.03 0 0.12
20 INT200304 Hdac2 Negative_regulation of Rorb 1 0.00 0 0.12
21 INT200318 Hdac1 Negative_regulation of Transcription of Lhcgr 1 0.03 0 0.12
22 INT200346 Hdac2 Negative_regulation of Lhcgr 1 0.04 0 0.12
23 INT200306 Hdac1 Negative_regulation of Rorb 1 0.00 0 0.12
24 INT200332 Binding of Rcor2 and Hdac1 1 0.15 0.3 0.12
25 INT200347 Hdac2 Negative_regulation of Transcription of Lhcgr 1 0.04 0 0.12
26 INT251114 Binding of AR and Ctnnb1 1 0.01 1 0.12
27 INT287267 EGF Positive_regulation of CDC42 1 0.12 0.16 0.11
28 INT268679 Binding of HDAC1 and NCOR2 3 0.17 2.8 0.07
29 INT331790 Binding of gr and Hdac2 1 0.01 0.74 0.07
30 INT331791 Akt1 Negative_regulation of Hdac2 1 0.03 0.8 0.07
31 INT331798 Regulation of Binding of gr and Hdac2 1 0.02 0.75 0.07
32 INT268678 Binding of HDAC2 and NCOR2 1 0.18 2.67 0.07
33 INT268676 Binding of HDAC1 and BCOR 1 0.01 1.31 0.04
34 INT181083 Binding of Akt1 and Cdc42 1 0.00 0.79 0.03
35 INT348592 Binding of HDAC1 and PPARG 1 0.23 0 0.03
36 INT319171 Binding of Cgn and Hdac1 1 0.00 0 0
37 INT196948 Hmga2 Positive_regulation of Hdac1 1 0.36 0.23 0
38 INT355603 Binding of CTNNA1 and Ctnnb1 1 0.00 1.07 0
39 INT220818 Binding of Ctnnb1 and Myc 1 0.06 0.13 0
40 INT333685 Binding of Trp53 and Hdac1 1 0.26 0.55 0
41 INT286566 Binding of Ctnnb1 and Cdh6 1 0.00 1 0
42 INT284920 Binding of HDAC1 and NCOR1 1 0.03 0.13 0
43 INT286562 Gene_expression of Pkd1 Positive_regulation of Ctnnb1 1 0.02 0.52 0
44 INT136693 Gtf3a Positive_regulation of Ctnnb1 1 0.05 0 0
45 INT234996 Ctnnd1 Positive_regulation of CDC42 1 0.01 0.07 0
46 INT284914 Binding of HDAC1 and NCK1 1 0.00 0.13 0
47 INT311398 Positive_regulation of Celf1 Positive_regulation of Hdac1 1 0.12 0.19 0
48 INT196946 Binding of E2f1 and Hdac1 1 0.26 0.65 0
49 INT220821 Binding of MAX and Ctnnb1 1 0.09 0.13 0
50 INT249149 Binding of Cdc42 and Was 1 0.08 0.18 0
51 INT337401 Binding of E2F1 and HDAC1 1 0.07 0 0
52 INT286561 Binding of Ctnnb1 and Cdh2 1 0.00 1.06 0
53 INT286567 Prkd1 Regulation of Ctnnb1 1 0.01 0.39 0
54 INT196956 Binding of Hmga2 and Hdac1 1 0.25 0.23 0
55 INT196941 Hdac1 Negative_regulation of Rb1 1 0.27 0.44 0
56 INT196944 Binding of Rb1 and Hdac1 1 0.24 0.4 0
57 INT301470 Binding of Smyd2 and Hdac1 1 0.35 0.31 0
58 INT319170 Casp3 Regulation of Hdac1 1 0.01 0.27 0
59 INT284995 Binding of HDAC1 and Sin3a 1 0.00 0.13 0
60 INT177783 Binding of HDAC1 and PCNA 1 0.09 0.5 0
61 INT286572 Binding of Ctnnb1 and Pkd1 1 0.02 0.96 0
62 INT181085 Binding of Cdc42 and Errfi1 1 0.08 0.67 0
63 INT333684 Binding of Hr and Hdac1 1 0.19 0.56 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for hair follicle placode formation. They are ordered first by their pain relevance and then by number of times they were reported in hair follicle placode formation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT177831 Gene_expression of HDAC1 24 0.65 21.37 8.37
2 INT4431 Negative_regulation of Eda 10 0.46 3.53 6.81
3 INT333909 Positive_regulation of Gene_expression of HDAC1 1 0.44 14.15 5.9
4 INT56404 Gene_expression of EDA 16 0.75 7.09 4.24
5 INT101567 Gene_expression of Ctnnb1 7 0.64 10.11 2.89
6 INT59287 Positive_regulation of Eda 5 0.40 1.25 2.36
7 INT74241 Positive_regulation of Gene_expression of EDA 3 0.49 4.93 2.24
8 INT43044 Gene_expression of Eda 3 0.75 0.69 2
9 INT81641 Gene_expression of Ctnnb1 23 0.72 14.93 1.97
10 INT123990 Positive_regulation of Ctnnb1 8 0.43 2.85 1.63
11 INT26393 Localization of Eda 4 0.60 0.18 1.63
12 INT99391 Localization of Ctnnb1 7 0.80 5.84 1.61
13 INT272884 Gene_expression of Hdac2 19 0.43 14.55 1.48
14 INT49402 Positive_regulation of EDA 6 0.61 4.23 1.43
15 INT333914 Transcription of HDAC1 1 0.34 3.04 1.37
16 INT198840 Transcription of EDA 1 0.58 0.97 1.26
17 INT4430 Regulation of Eda 2 0.23 0.38 1.24
18 INT99389 Negative_regulation of Ctnnb1 8 0.45 3.97 1.21
19 INT97955 Positive_regulation of CDC42 8 0.49 2.47 1.19
20 INT272879 Negative_regulation of Hdac2 8 0.37 5.96 1.17
21 INT54044 Negative_regulation of EDA 7 0.42 2.54 1.14
22 INT260447 Binding of HDAC1 8 0.23 4.47 1.12
23 INT13655 Binding of Eda 4 0.36 0.97 1.1
24 INT68339 Gene_expression of HDAC2 3 0.51 1.71 1.1
25 INT101570 Positive_regulation of Gene_expression of Ctnnb1 1 0.58 5.7 1.07
26 INT333907 Positive_regulation of HDAC1 4 0.32 3.07 1.03
27 INT317791 Localization of HDAC2 2 0.50 2.31 0.99
28 INT161682 Positive_regulation of Cdc42 8 0.53 4.55 0.9
29 INT101566 Negative_regulation of Gene_expression of Ctnnb1 1 0.35 2.28 0.88
30 INT200250 Binding of Hdac2 6 0.22 2.97 0.76
31 INT284955 Localization of HDAC1 2 0.47 1.71 0.74
32 INT272883 Positive_regulation of Gene_expression of Hdac2 5 0.30 4.64 0.7
33 INT272886 Negative_regulation of Gene_expression of Hdac2 4 0.23 4.63 0.69
34 INT99390 Regulation of Ctnnb1 4 0.62 3.12 0.64
35 INT180107 Regulation of Cdc42 3 0.16 0.18 0.6
36 INT97956 Negative_regulation of CDC42 3 0.27 1.58 0.55
37 INT76960 Negative_regulation of Ctnnb1 5 0.57 3.46 0.53
38 INT272868 Positive_regulation of Hdac2 3 0.27 2.15 0.5
39 INT177842 Negative_regulation of HDAC1 6 0.31 4.65 0.49
40 INT81645 Positive_regulation of Gene_expression of Ctnnb1 6 0.63 3.78 0.47
41 INT76958 Positive_regulation of Ctnnb1 14 0.64 5.48 0.41
42 INT95872 Localization of Ctnnb1 7 0.74 2.75 0.4
43 INT81644 Regulation of Ctnnb1 5 0.41 3.38 0.37
44 INT81643 Regulation of Gene_expression of Ctnnb1 3 0.57 1.5 0.37
45 INT196927 Binding of Hdac1 9 0.36 2.31 0.36
46 INT333916 Negative_regulation of HDAC2 2 0.18 1.38 0.36
47 INT158794 Binding of EDA 2 0.47 1.61 0.33
48 INT272882 Positive_regulation of Binding of Hdac2 2 0.20 1.12 0.32
49 INT108324 Negative_regulation of Gene_expression of Ctnnb1 1 0.06 1.43 0.31
50 INT177856 Negative_regulation of Gene_expression of HDAC2 1 0.19 0.12 0.3
51 INT196917 Gene_expression of Hdac1 15 0.71 3.66 0.28
52 INT151719 Negative_regulation of Positive_regulation of Ctnnb1 1 0.23 1.9 0.24
53 INT183881 Localization of CDC42 3 0.49 1.92 0.23
54 INT183876 Regulation of CDC42 3 0.30 1.94 0.19
55 INT99392 Negative_regulation of Localization of Ctnnb1 2 0.59 1.43 0.17
56 INT151721 Negative_regulation of Localization of Ctnnb1 1 0.23 0.96 0.17
57 INT325506 Positive_regulation of Localization of Ctnnb1 1 0.05 0.28 0.17
58 INT197290 Gene_expression of Cdc42 9 0.35 2.52 0.15
59 INT266991 Regulation of Hdac2 2 0.07 0.74 0.15
60 INT130374 Transcription of Ctnnb1 1 0.19 0 0.13
61 INT206133 Binding of CDC42 3 0.25 0.8 0.12
62 INT196934 Negative_regulation of Hdac1 4 0.39 1.41 0.11
63 INT49401 Regulation of EDA 1 0.23 0.07 0.11
64 INT331783 Regulation of Negative_regulation of Hdac1 1 0.04 0.98 0.11
65 INT49403 Positive_regulation of Regulation of EDA 1 0.40 0.07 0.11
66 INT197282 Positive_regulation of Gene_expression of Cdc42 3 0.26 0.12 0.08
67 INT331786 Negative_regulation of Binding of Hdac2 1 0.11 1.2 0.08
68 INT284980 Positive_regulation of Protein_catabolism of HDAC2 1 0.20 0.81 0.08
69 INT284976 Protein_catabolism of HDAC2 1 0.28 0.8 0.08
70 INT206169 Gene_expression of CDC42 2 0.26 1.05 0.05
71 INT331784 Negative_regulation of Positive_regulation of Hdac2 1 0.11 0.52 0.05
72 INT206167 Positive_regulation of Gene_expression of CDC42 1 0.08 0.05 0.05
73 INT284973 Negative_regulation of Negative_regulation of HDAC1 1 0.20 1.59 0.04
74 INT328554 Regulation of HDAC1 1 0.26 1.12 0.03
75 INT331778 Regulation of Phosphorylation of Hdac2 1 0.11 0.49 0.03
76 INT331787 Phosphorylation of Hdac2 1 0.20 0.49 0.03
77 INT277595 Localization of Hdac1 4 0.73 0.81 0
78 INT254795 Negative_regulation of Cdc42 2 0.12 1.53 0
79 INT76959 Binding of Ctnnb1 2 0.34 0.69 0
80 INT261751 Regulation of Hdac1 2 0.41 0 0
81 INT350509 Phosphorylation of HDAC1 1 0.25 0.62 0
82 INT270614 Localization of Cdc42 1 0.55 0.95 0
83 INT230651 Phosphorylation of Ctnnb1 1 0.10 0 0
84 INT230674 Positive_regulation of Phosphorylation of Ctnnb1 1 0.06 0 0
85 INT158793 Negative_regulation of Positive_regulation of EDA 1 0.38 0 0
86 INT326137 Protein_catabolism of Ctnnb1 1 0.02 1.08 0
87 INT337478 Binding of HDAC2 1 0.14 0.07 0
88 INT319154 Transcription of Hdac1 1 0.66 0 0
89 INT197294 Regulation of Gene_expression of Cdc42 1 0.13 0 0
90 INT319156 Negative_regulation of Gene_expression of Hdac1 1 0.39 0.22 0
91 INT355576 Negative_regulation of Negative_regulation of Ctnnb1 1 0.02 1.14 0
92 INT277596 Phosphorylation of Hdac1 1 0.61 0.59 0
93 INT282269 Binding of Cdc42 1 0.08 0.33 0
94 INT220769 Positive_regulation of Positive_regulation of Ctnnb1 1 0.10 0 0
95 INT319169 Negative_regulation of Transcription of Hdac1 1 0.54 0 0
96 INT287281 Positive_regulation of Positive_regulation of CDC42 1 0.26 0 0
97 INT282272 Positive_regulation of Binding of Cdc42 1 0.11 0.33 0
98 INT355198 Positive_regulation of Localization of Hdac1 1 0.19 0.48 0
99 INT158795 Negative_regulation of Gene_expression of EDA 1 0.37 0 0
100 INT256367 Localization of EDA 1 0.13 0 0
101 INT319162 Regulation of Gene_expression of Hdac1 1 0.56 0 0
102 INT319152 Positive_regulation of Gene_expression of Hdac1 1 0.46 0 0
103 INT311329 Positive_regulation of Hdac1 1 0.19 0.14 0
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