GO:0061001

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Name regulation of dendritic spine morphogenesis
Categary Process
Go Slim No
Go Link GO:0061001
Unique Molecular Interactions 62
Total Molecular Interactions 78
Total Single Events 577
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of dendritic spine morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported for regulation of dendritic spine morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT158711 Cdk5 Positive_regulation of Phosphorylation of Trh 1 0.02 0 1.46
2 INT134476 Cdk5 Regulation of Map2k1 1 0.69 0.88 0.71
3 INT273235 Binding of Cdk5 and Cdk5r1 1 0.24 6.06 0.46
4 INT273234 Negative_regulation of Cdk5 Positive_regulation of Ptprs 1 0.14 1.26 0.34
5 INT339645 Binding of Cdk5r1 and Ebi3 1 0.01 0.78 0.31
6 INT298996 Il18 Positive_regulation of Gene_expression of Cdk5r1 1 0.03 1.65 0.29
7 INT298995 Il18 Positive_regulation of Gene_expression of Cdk5 1 0.12 1.65 0.29
8 INT299008 Il18 Positive_regulation of Transcription of Cdk5 1 0.12 1.65 0.29
9 INT299011 Il18 Positive_regulation of Transcription of Cdk5r1 1 0.03 1.65 0.29
10 INT247949 Cdk5r1 Positive_regulation of Cdk5 1 0.26 1.12 0.28
11 INT337113 Ppp1r1b Negative_regulation of Phosphorylation of Cdk5 1 0.11 0.28 0.27
12 INT273232 Negative_regulation of Binding of Cdk5 and Cdk5r1 1 0.28 3.16 0.23
13 INT273237 Cdk5 Positive_regulation of Protein_catabolism of Grin2b 1 0.45 1.31 0.22
14 INT326831 Cdk5r2 Positive_regulation of Binding of Cdk5r1 1 0.01 0.95 0.21
15 INT326834 Cdk5r2 Positive_regulation of Cdk5 1 0.02 0.96 0.21
16 INT221955 Binding of ELAVL1 and CDK5R1 1 0.01 0.93 0.19
17 INT221956 CDK5R1 Regulation of Positive_regulation of CDK5 1 0.21 0.62 0.19
18 INT298998 Il18 Positive_regulation of Cdk5 1 0.11 0.36 0.17
19 INT164791 Cdk5r1 Positive_regulation of Cdk5 1 0.30 0.25 0.17
20 INT164790 Cdk5r1 Positive_regulation of Trib3 1 0.02 0.25 0.17
21 INT299001 Il18 Positive_regulation of Cdk5r1 1 0.03 0.36 0.17
22 INT273233 Negative_regulation of Cdk5 Negative_regulation of Positive_regulation of Ltp 1 0.20 0.39 0.13
23 INT273239 Cdk5 Positive_regulation of Positive_regulation of GRIN1 1 0.51 0.37 0.12
24 INT221958 CDK5R1 Positive_regulation of Positive_regulation of CDK5 1 0.36 0.38 0.1
25 INT273236 Cdk5 Positive_regulation of Car2 1 0.13 0.45 0.1
26 INT221959 Binding of CDK5 and CDK5R1 1 0.28 0.53 0.1
27 INT201748 Car2 Positive_regulation of Cdk5r1 1 0.00 0.67 0.09
28 INT201751 Car2 Positive_regulation of Cdk5 1 0.00 0.67 0.09
29 INT221954 Binding of CDK5 and CDK5R2 1 0.02 0.36 0.09
30 INT247948 Positive_regulation of Cdk5r1 Positive_regulation of Cdk5 1 0.26 0.16 0.07
31 INT332329 Binding of Cdk5 and P2rx3 1 0.22 0.05 0.05
32 INT332331 Binding of Cdk5 and Rbm39 1 0.00 0.05 0.05
33 INT221952 UTS2R Regulation of Protein_catabolism of CDK5R1 1 0.10 0.3 0.04
34 INT326830 Cdk5r1 Positive_regulation of Positive_regulation of Cdk5 1 0.09 0.16 0.04
35 INT221953 UTS2R Positive_regulation of Gene_expression of CDK5R1 1 0.16 0.23 0.04
36 INT221639 Fyn Positive_regulation of Phosphorylation of Cdk5 1 0.14 0.28 0.03
37 INT221962 UTS2R Regulation of Gene_expression of CDK5R1 1 0.09 0.43 0.03
38 INT221661 Sema3a Positive_regulation of Phosphorylation of Cdk5 1 0.19 0.28 0.03
39 INT332330 Cdk5 Negative_regulation of Pirt 1 0.00 0 0.03
40 INT219352 CDK5 Negative_regulation of PAK1 1 0.22 0.72 0.03
41 INT221963 ELAVL1 Regulation of Gene_expression of CDK5R1 1 0.01 0.58 0.03
42 INT221613 Binding of Cdk5 and Fyn 1 0.10 0.29 0.03
43 INT221617 Fyn Positive_regulation of Cdk5 1 0.13 0.28 0.03
44 INT201734 Binding of Akt1 and Cdk5 1 0.01 0.31 0
45 INT201738 Positive_regulation of Binding of Akt1 and Cdk5 1 0.01 0.31 0
46 INT313384 Binding of PDLIM5 and ZMYND10 1 0.04 0.82 0
47 INT201731 Negative_regulation of Binding of Akt1 and Cdk5 1 0.01 0.31 0
48 INT268446 Cdk5 Positive_regulation of Cdk5r1 1 0.02 0.58 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of dendritic spine morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported in regulation of dendritic spine morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT109223 Negative_regulation of Cdk5 14 0.59 3.27 12.73
2 INT101602 Positive_regulation of Cdk5 15 0.70 4.1 8.96
3 INT127555 Negative_regulation of Cdk5 59 0.59 50.2 8.45
4 INT157580 Phosphorylation of Cdk5 4 0.77 0.73 8.33
5 INT127556 Positive_regulation of Cdk5 35 0.70 19.6 5.95
6 INT101604 Regulation of Cdk5 10 0.61 2.2 5.53
7 INT134468 Gene_expression of Cdk5r1 26 0.48 27.09 5.2
8 INT109219 Negative_regulation of Cdk5r1 5 0.43 1.22 4.25
9 INT148495 Regulation of Cdk5 6 0.58 5.42 3.95
10 INT201632 Positive_regulation of Cdk5r1 20 0.40 21.6 2.75
11 INT196733 Gene_expression of Cdk5 25 0.76 18.25 2.64
12 INT138789 Gene_expression of Cdk5 6 0.76 5.19 2.62
13 INT101603 Positive_regulation of Cdk5r1 4 0.56 1.12 2.35
14 INT148494 Binding of Cdk5 6 0.40 5.97 2.31
15 INT112905 Phosphorylation of Cdk5 15 0.82 2.78 2.3
16 INT157579 Binding of Cdk5 3 0.35 0.47 2.13
17 INT148492 Positive_regulation of Binding of Cdk5 1 0.47 0.51 1.86
18 INT158710 Negative_regulation of Binding of Cdk5 1 0.40 0 1.84
19 INT101599 Gene_expression of Cdk5r1 5 0.63 1.27 1.68
20 INT101601 Regulation of Cdk5r1 3 0.50 1.2 1.46
21 INT109222 Positive_regulation of Negative_regulation of Cdk5 2 0.50 0.23 1.39
22 INT158709 Negative_regulation of Phosphorylation of Cdk5 1 0.40 0 1.39
23 INT114969 Gene_expression of CDK5R1 3 0.75 11.24 1.33
24 INT138783 Positive_regulation of Gene_expression of Cdk5r1 2 0.38 0.68 1.15
25 INT203890 Positive_regulation of Gene_expression of Cdk5r1 9 0.40 9.13 1.11
26 INT273221 Positive_regulation of Negative_regulation of Cdk5 8 0.49 9.89 1.03
27 INT109221 Positive_regulation of Negative_regulation of Cdk5r1 1 0.37 0.15 0.95
28 INT203893 Positive_regulation of Gene_expression of Cdk5 2 0.49 7.12 0.92
29 INT138788 Positive_regulation of Gene_expression of Cdk5 1 0.49 0.44 0.91
30 INT127452 Positive_regulation of CDK5 5 0.32 1.88 0.87
31 INT203892 Positive_regulation of Positive_regulation of Cdk5 4 0.49 4.02 0.85
32 INT219358 Gene_expression of CDK5 9 0.58 5.65 0.81
33 INT138787 Positive_regulation of Positive_regulation of Cdk5 1 0.49 0.38 0.81
34 INT77663 Positive_regulation of CDK5R1 3 0.67 0.43 0.79
35 INT273220 Positive_regulation of Positive_regulation of Cdk5r1 4 0.40 5.3 0.75
36 INT196790 Localization of Cdk5 6 0.74 2.6 0.67
37 INT134472 Binding of Cdk5r1 4 0.26 4.25 0.65
38 INT257455 Binding of PDLIM5 2 0.08 1.72 0.64
39 INT77662 Regulation of CDK5R1 2 0.60 1.93 0.63
40 INT221978 Regulation of Gene_expression of CDK5R1 1 0.59 5.08 0.61
41 INT127557 Positive_regulation of Phosphorylation of Cdk5 2 0.50 0.43 0.56
42 INT273230 Negative_regulation of Cdk5r1 1 0.25 4.48 0.53
43 INT201636 Protein_catabolism of Cdk5r1 3 0.18 2.79 0.44
44 INT326821 Positive_regulation of Protein_catabolism of Cdk5r1 1 0.13 1.9 0.41
45 INT273218 Negative_regulation of Negative_regulation of Cdk5 1 0.42 3.06 0.37
46 INT221973 Negative_regulation of CDK5 4 0.57 2.26 0.36
47 INT247937 Localization of Cdk5r1 3 0.41 1.21 0.3
48 INT298974 Transcription of Cdk5r1 1 0.04 1.64 0.28
49 INT326820 Negative_regulation of Positive_regulation of Cdk5 1 0.36 1.27 0.28
50 INT298972 Transcription of Cdk5 1 0.15 1.63 0.28
51 INT273216 Negative_regulation of Gene_expression of Cdk5r1 1 0.25 1.73 0.25
52 INT164788 Regulation of Gene_expression of Cdk5 1 0.27 0.31 0.24
53 INT326823 Positive_regulation of Localization of Cdk5r1 1 0.09 0.9 0.2
54 INT219375 Localization of CDK5 4 0.52 2.8 0.19
55 INT221974 Phosphorylation of CDK5 1 0.56 0.99 0.19
56 INT134469 Positive_regulation of Binding of Cdk5r1 1 0.35 0.4 0.18
57 INT273226 Negative_regulation of Gene_expression of Cdk5 2 0.42 0.79 0.17
58 INT23890 Binding of CDK5R1 2 0.36 0.23 0.16
59 INT157582 Regulation of Phosphorylation of Cdk5 1 0.26 0.25 0.16
60 INT221972 Regulation of CDK5 1 0.42 1.87 0.16
61 INT221969 Negative_regulation of CDK5R1 1 0.41 0.44 0.13
62 INT326822 Negative_regulation of Phosphorylation of Cdk5 1 0.36 0.43 0.12
63 INT341559 Positive_regulation of Gene_expression of CDK5 1 0.23 0.25 0.11
64 INT101600 Regulation of Gene_expression of Cdk5r1 1 0.50 0.16 0.1
65 INT221976 Phosphorylation of CDK5R1 1 0.61 0.4 0.09
66 INT201655 Negative_regulation of Binding of Cdk5 1 0.06 0.9 0.09
67 INT221965 Positive_regulation of Gene_expression of CDK5R1 1 0.67 0.29 0.08
68 INT221977 Transcription of CDK5R1 1 0.51 0.59 0.08
69 INT341567 Negative_regulation of Gene_expression of CDK5 1 0.27 0.24 0.07
70 INT219355 Binding of CDK5 3 0.35 2.02 0.06
71 INT221975 Regulation of Transcription of CDK5R1 1 0.26 0.15 0.05
72 INT171650 Protein_catabolism of CDK5R1 2 0.63 0.47 0.04
73 INT201634 Negative_regulation of Positive_regulation of Cdk5r1 1 0.02 0.31 0
74 INT268444 Regulation of Positive_regulation of Cdk5 1 0.08 0.66 0
75 INT274108 Phosphorylation of Cdk5r1 1 0.01 0.84 0
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