GO:0061037

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Name negative regulation of cartilage development
Categary Process
Go Slim No
Go Link GO:0061037
Unique Molecular Interactions 225
Total Molecular Interactions 324
Total Single Events 2195
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of cartilage development. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of cartilage development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT83169 Binding of Cck and Lep 7 0.42 1.58 2.78
2 INT278948 LEP Positive_regulation of Gene_expression of PTGER2 1 0.09 4.04 2.69
3 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
4 INT83170 Lep Regulation of Cck 5 0.43 0.68 1.96
5 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
6 INT117311 HP Positive_regulation of Lep 1 0.00 1.78 1.01
7 INT278962 LEP Positive_regulation of CPOX 1 0.05 1.33 1
8 INT278940 LEP Positive_regulation of Gene_expression of IL8 1 0.34 1.68 0.96
9 INT130948 Amt Regulation of Gene_expression of LEP 1 0.00 1.04 0.78
10 INT130949 Amt Regulation of LEP 1 0.00 1.04 0.77
11 INT278958 LEP Positive_regulation of IL1B 1 0.33 1.91 0.74
12 INT214163 Binding of Lep and Nts 1 0.04 0.21 0.74
13 INT89009 Lep Positive_regulation of Cck 2 0.67 0.43 0.69
14 INT278956 LEP Regulation of Gene_expression of IL8 1 0.30 1.11 0.69
15 INT278968 LEP Regulation of Gene_expression of IL6 1 0.29 1.11 0.69
16 INT278951 LEP Regulation of Gene_expression of PTGER2 1 0.07 1.11 0.69
17 INT278965 LEP Positive_regulation of Gene_expression of NOS2 2 0.29 2.12 0.66
18 INT323773 Binding of Il6 and Lep 1 0.29 3.54 0.6
19 INT349083 Binding of Lep and Rtn1 1 0.09 1.68 0.57
20 INT91339 Binding of Lep and Cck 1 0.28 0.34 0.56
21 INT113162 Lep Positive_regulation of Positive_regulation of Insrr 1 0.03 0 0.55
22 INT253834 Cck Regulation of Lep 1 0.19 0.23 0.55
23 INT204087 IL1B Positive_regulation of Gene_expression of LEP 1 0.09 2.6 0.54
24 INT214160 Binding of Lep and Mc4r 1 0.29 1.31 0.53
25 INT214143 Binding of Lep and Pomc 1 0.27 1.2 0.53
26 INT162890 Negative_regulation of Binding of LEP and Tnf 1 0.03 0.49 0.48
27 INT162889 Binding of LEP and Tnf 1 0.03 0.49 0.48
28 INT132509 Binding of LEP and Cck 1 0.13 0.16 0.45
29 INT323880 Binding of BMI1 and LEP 1 0.02 3.97 0.41
30 INT83171 Cck Regulation of Lep 1 0.30 0.09 0.4
31 INT97395 Lep Positive_regulation of Stat3 1 0.67 0.42 0.4
32 INT143747 Binding of IL6 and LEP 2 0.04 4.05 0.38
33 INT300488 Binding of CRP and LEP 1 0.46 2.03 0.37
34 INT226785 Angpt2 Positive_regulation of Localization of Lep 1 0.01 1.65 0.36
35 INT278966 MAPK14 Positive_regulation of Gene_expression of LEP 1 0.16 0.62 0.36
36 INT278949 JAK3 Positive_regulation of Gene_expression of LEP 1 0.42 0.63 0.36
37 INT323885 LEP Regulation of Gene_expression of NOS2 1 0.26 1.07 0.35
38 INT213484 Binding of Lep and Pik3c3 1 0.01 0 0.35
39 INT44983 Ltc4s Positive_regulation of Rara 1 0.01 0.15 0.33
40 INT207184 Binding of Adipoq and Lep 1 0.25 2.45 0.33
41 INT323870 LEP Regulation of Gene_expression of MMP13 1 0.21 1.76 0.33
42 INT303993 Lep Positive_regulation of Gene_expression of IL2 1 0.15 0.24 0.33
43 INT44985 KNG1 Positive_regulation of Rara 1 0.00 0.15 0.32
44 INT105873 Ins1 Negative_regulation of Positive_regulation of Lep 1 0.27 0.67 0.31
45 INT278942 LEP Regulation of IL6 1 0.29 0.61 0.31
46 INT278939 LEP Regulation of IL8 1 0.13 0.61 0.31
47 INT213485 Lep Positive_regulation of Localization of Grin2a 1 0.19 0 0.31
48 INT278969 LEP Regulation of PTGER2 1 0.03 0.6 0.31
49 INT105874 Lep Negative_regulation of Positive_regulation of Ins1 1 0.27 0.67 0.31
50 INT226989 Lias Regulation of Gene_expression of Lep 1 0.10 0.91 0.3
51 INT278961 IL6 Regulation of Gene_expression of LEP 1 0.29 0.89 0.3
52 INT303983 Lep Positive_regulation of CXCL10 1 0.06 0.31 0.29
53 INT333886 Binding of Lep and Positive_regulation of Gene_expression of Nos2 1 0.39 0.73 0.29
54 INT303998 Lep Positive_regulation of Localization of IL1RAPL1 1 0.04 0.31 0.29
55 INT333887 Binding of Lep and Positive_regulation of Gene_expression of Il1 1 0.17 0.73 0.29
56 INT303995 Lep Positive_regulation of PSME1 1 0.09 0.32 0.29
57 INT211997 CORD1 Positive_regulation of Rara 1 0.01 0.68 0.29
58 INT303984 Lep Positive_regulation of Gene_expression of IL8 1 0.06 0.85 0.28
59 INT100531 Cck Positive_regulation of Lep 1 0.70 0.15 0.26
60 INT228611 Binding of DNMT3B and LEP 1 0.04 0 0.25
61 INT218732 Lep Regulation of Gene_expression of Trh 1 0.19 0.18 0.25
62 INT125748 Binding of LEP and Gh 1 0.00 0.52 0.24
63 INT306795 Binding of LEP and SFTPD 1 0.08 1.13 0.23
64 INT303988 Lep Positive_regulation of Gene_expression of ISYNA1 1 0.06 0.55 0.23
65 INT108842 RARA Positive_regulation of Gene_expression of GDF15 1 0.52 0.68 0.23
66 INT323883 BMI1 Regulation of LEP 1 0.02 2.39 0.23
67 INT102937 Gnrh1 Positive_regulation of Gene_expression of Lep 1 0.50 0 0.22
68 INT110653 Lep Regulation of Localization of Cck 1 0.06 0.22 0.22
69 INT269180 LEP Positive_regulation of Localization of TNF 1 0.01 0.99 0.21
70 INT323873 LEP Regulation of Gene_expression of TIMP2 1 0.31 0.63 0.21
71 INT207185 Binding of Bmi1 and Lep 1 0.01 1.7 0.21
72 INT222482 Lep Positive_regulation of Localization of Gh1 1 0.02 1.02 0.2
73 INT304001 Lep Negative_regulation of ICAM3 1 0.07 0.35 0.2
74 INT333889 Lep Regulation of Col7a1 1 0.04 0.41 0.2
75 INT303979 Lep Positive_regulation of ITGB2 1 0.11 0.35 0.2
76 INT256576 Lep Regulation of Localization of Ins1 1 0.57 2.08 0.2
77 INT303991 Lep Negative_regulation of SELL 1 0.04 0.35 0.2
78 INT217661 LEP Positive_regulation of INS 2 0.25 1.85 0.19
79 INT327814 Rab8a Regulation of Regulation of Lep 1 0.01 0.15 0.19
80 INT327813 Rab8a Regulation of Lep 1 0.01 0.15 0.19
81 INT303964 Lep Positive_regulation of Icam1 1 0.24 0.35 0.19
82 INT333888 Lep Regulation of Localization of GAG 1 0.68 0.38 0.19
83 INT214170 Binding of DST and Lep 1 0.02 0.17 0.18
84 INT303981 Lep Positive_regulation of Localization of CXCL1 1 0.02 0.34 0.18
85 INT226988 Lias Positive_regulation of Localization of Lep 1 0.08 0.3 0.17
86 INT313023 Binding of Rara and Rxra 1 0.06 0.73 0.17
87 INT303967 Lep Positive_regulation of Gene_expression of Icam1 1 0.24 0.58 0.16
88 INT303980 Lep Positive_regulation of Transcription of IL2 1 0.10 0.24 0.16
89 INT217667 LEP Negative_regulation of Localization of INS 1 0.15 1.18 0.14
90 INT217664 LEP Negative_regulation of INS 1 0.15 1.18 0.14
91 INT323877 LEP Positive_regulation of SOAT1 1 0.20 1.26 0.14
92 INT192106 Regulation of Binding of Rara and Retsat 1 0.00 0.83 0.13
93 INT139975 Binding of LEP and Prl 1 0.02 0.49 0.13
94 INT328060 LEP Positive_regulation of FAAH 1 0.06 0.7 0.13
95 INT346714 LEP Regulation of GALP 1 0.06 0.08 0.13
96 INT192105 Binding of Rara and Retsat 1 0.00 0.83 0.13
97 INT81179 LEP Regulation of Localization of GH1 1 0.11 0.91 0.12
98 INT214141 Binding of Lep and Lepr 1 0.32 0.82 0.12
99 INT150532 LEP Negative_regulation of Adipoq 1 0.00 1.34 0.12
100 INT150533 Positive_regulation of LEP Negative_regulation of Adipoq 1 0.00 1.34 0.12
101 INT164746 Binding of LEP and Adipoq 1 0.07 0.69 0.12
102 INT323871 LEP Regulation of Gene_expression of IGF1 1 0.14 1.19 0.11
103 INT270746 INS Regulation of LEP 1 0.07 0.72 0.11
104 INT294742 Lep Positive_regulation of Localization of Icam1 1 0.15 0.48 0.11
105 INT163817 Lep Positive_regulation of Phosphorylation of Akt1 1 0.33 0.31 0.11
106 INT222472 Lep Positive_regulation of Localization of Cartpt 1 0.05 0 0.11
107 INT303989 Lep Positive_regulation of IL12A 1 0.05 0.39 0.11
108 INT303966 Lep Regulation of Il1 2 0.09 0.41 0.1
109 INT303990 Binding of Lep and Positive_regulation of Gene_expression of LPL 1 0.03 0.35 0.1
110 INT192104 Binding of Rara and Rxrg 1 0.00 0.82 0.1
111 INT323879 LEP Regulation of SOAT1 1 0.15 1.15 0.1
112 INT204086 TNF Positive_regulation of Gene_expression of LEP 1 0.48 0.74 0.1
113 INT304000 Lep Negative_regulation of Positive_regulation of CASP8 1 0.04 0.25 0.1
114 INT123864 Lep Positive_regulation of Positive_regulation of Cck 1 0.45 0.1 0.09
115 INT242324 Lep Regulation of Gene_expression of Ucp1 1 0.58 1.47 0.09
116 INT142418 Lep Positive_regulation of Gene_expression of Ghrl 1 0.48 1.66 0.09
117 INT306794 Binding of LEP and COPD 1 0.15 3.94 0.09
118 INT213482 Lep Positive_regulation of Mapk1 1 0.06 0.08 0.09
119 INT300486 LEP Positive_regulation of ROS1 1 0.15 0.91 0.09
120 INT323868 LEP Regulation of Transcription of COL1A2 1 0.10 0.98 0.09
121 INT222545 Lep Negative_regulation of Nmb 1 0.04 0.52 0.08
122 INT123866 Lep Negative_regulation of Olfr544 1 0.00 0.09 0.08
123 INT303999 Lep Positive_regulation of Gene_expression of ITGA2 1 0.06 0.29 0.08
124 INT332287 LEP Positive_regulation of Phosphorylation of IRS1 1 0.20 1.48 0.08
125 INT323881 BMI1 Regulation of Gene_expression of LEP 1 0.03 1.09 0.08
126 INT323876 LEP Regulation of COL1A2 1 0.10 0.86 0.08
127 INT268325 Lep Positive_regulation of Ptgs2 1 0.09 0.39 0.08
128 INT201380 RARA Positive_regulation of Regulation of CPOX 1 0.07 0.21 0.08
129 INT303970 Lep Positive_regulation of Gene_expression of Itga2 1 0.09 0.29 0.08
130 INT294743 Lep Positive_regulation of Transcription of Il6 1 0.18 0.42 0.07
131 INT294740 Lep Positive_regulation of Transcription of Ccl2 1 0.08 0.42 0.07
132 INT323872 LEP Positive_regulation of Gene_expression of IGF1 1 0.35 0.77 0.07
133 INT303997 IL1RL1 Positive_regulation of Lep 1 0.01 0.2 0.07
134 INT214153 Lep Regulation of Transcription of Nucb2 1 0.35 0.15 0.06
135 INT253377 Lep Negative_regulation of Phosphorylation of Prkaa2 1 0.24 1.24 0.06
136 INT197727 Binding of RARA and Positive_regulation of PPARA 1 0.02 0.96 0.05
137 INT323878 Binding of LEP and MMP13 1 0.17 0.77 0.05
138 INT267152 Binding of LEP and DDX12P 1 0.00 0.69 0.05
139 INT267157 LEP Positive_regulation of ADIPOQ 1 0.10 0.51 0.05
140 INT345965 Binding of Lep and al44 1 0.01 1.43 0.05
141 INT314135 Negative_regulation of Nos2 Positive_regulation of Lep 1 0.52 0.44 0.05
142 INT327821 GPRC6A Regulation of Gene_expression of Lep 1 0.00 0.5 0.05
143 INT327822 INCENP Regulation of Gene_expression of Lep 1 0.00 0.5 0.05
144 INT267153 Binding of LEP and SUGT1 1 0.02 0.69 0.05
145 INT253376 Lep Regulation of Mtor 1 0.17 0.08 0.04
146 INT303986 Lep Positive_regulation of Gene_expression of TNF 1 0.49 0.29 0.04
147 INT332684 Binding of Edn1 and Lep 1 0.09 1.11 0.04
148 INT253363 Lep Regulation of Prkaa2 1 0.15 0.08 0.04
149 INT222534 Gnrh1 Positive_regulation of Localization of Lep 1 0.07 0 0.04
150 INT303996 Lep Positive_regulation of Gene_expression of IL12A 1 0.08 0.29 0.04
151 INT303965 Lep Positive_regulation of Gene_expression of Il6 1 0.07 0.29 0.04
152 INT291714 Binding of RARA and Rxra 3 0.07 0.2 0.03
153 INT249046 Binding of LEP and ARID1B 1 0.01 1.3 0.03
154 INT231438 LEP Positive_regulation of Negative_regulation of NOS3 1 0.09 0.32 0.03
155 INT253374 Lep Positive_regulation of Phosphorylation of Eif4ebp1 1 0.04 0.16 0.03
156 INT253375 Lep Positive_regulation of Phosphorylation of Rps6kb1 1 0.41 0.16 0.03
157 INT253414 Lep Negative_regulation of BCL2A1 1 0.16 0 0.03
158 INT231439 LEP Positive_regulation of Negative_regulation of AKT1 1 0.06 0.32 0.03
159 INT333885 Lep Positive_regulation of Il1 1 0.17 0.05 0.03
160 INT253370 Lep Negative_regulation of Prkaa2 1 0.29 0.18 0.03
161 INT213160 AGT Positive_regulation of Gene_expression of LEP 1 0.08 1.29 0.03
162 INT182924 Binding of RARA and NR1H4 3 0.02 1.9 0
163 INT182918 Binding of DR1 and RARA 2 0.08 0 0
164 INT174290 Lep Positive_regulation of Pomc 2 0.50 0.47 0
165 INT182949 Binding of RARA and VDR 1 0.20 0 0
166 INT138526 Lep Positive_regulation of Localization of Gnrh1 1 0.39 0 0
167 INT305279 Lep Regulation of Gene_expression of Akt1 1 0.18 0.83 0
168 INT253368 Positive_regulation of Lep Positive_regulation of Prkaa2 1 0.26 0.19 0
169 INT187675 DBT Positive_regulation of Gene_expression of LEP 1 0.04 0.27 0
170 INT305273 Binding of Lep and Leprot 1 0.06 0.92 0
171 INT214139 Lep Regulation of Localization of Pomc 1 0.20 0.4 0
172 INT214155 Lep Regulation of Gene_expression of Pomc 1 0.20 0.4 0
173 INT314133 Lep Positive_regulation of Gene_expression of Ppargc1a 1 0.51 0.79 0
174 INT249045 CENPJ Regulation of Regulation of LEP 1 0.14 0.81 0
175 INT305278 Lep Negative_regulation of Obsty1 1 0.07 0.94 0
176 INT303963 Lep Positive_regulation of Gene_expression of Il7 1 0.02 0.41 0
177 INT174287 Agrp Positive_regulation of Lep 1 0.19 0.49 0
178 INT163585 Lep Positive_regulation of Gene_expression of Epm2a 1 0.03 0.14 0
179 INT182919 TGFBI Regulation of RARA 1 0.29 0.08 0
180 INT289537 Lep Negative_regulation of Sirt1 1 0.20 0.05 0
181 INT225085 Binding of ADM and Negative_regulation of LEP 1 0.16 1.04 0
182 INT305272 Gene_expression of Lep Positive_regulation of Positive_regulation of Stat3 1 0.40 0.46 0
183 INT305264 Positive_regulation of Binding of Lep and Leprot 1 0.08 0.93 0
184 INT305280 Lep Positive_regulation of Gene_expression of Leprot 1 0.07 1.03 0
185 INT305258 Lep Regulation of Gene_expression of Stat3 1 0.24 0.92 0
186 INT342366 Binding of Rara and OSBPL1A 1 0.16 0 0
187 INT289532 Lep Regulation of Arc 1 0.04 0.19 0
188 INT305277 Positive_regulation of Binding of Lep and Obsty1 1 0.08 0.93 0
189 INT182961 Binding of RARA and KCNIP3 1 0.21 0.76 0
190 INT187667 DBT Positive_regulation of Localization of LEP 1 0.05 0.55 0
191 INT288214 Lep Negative_regulation of Gene_expression of Ins1 1 0.35 0.05 0
192 INT305271 Binding of Lep and Obsty1 1 0.06 4.86 0
193 INT204085 Binding of LEP and TNF 1 0.37 0.39 0
194 INT328375 Ghrl Negative_regulation of LEP 1 0.07 0.15 0
195 INT174288 Lep Positive_regulation of Npy 1 0.36 0.45 0
196 INT291682 Positive_regulation of Binding of RARA and TNFRSF10B 1 0.03 0 0
197 INT305267 Lep Regulation of Obsty1 1 0.04 0.97 0
198 INT174283 Lep Negative_regulation of Agrp 1 0.32 0.48 0
199 INT253364 Lep Positive_regulation of Rps6kb1 1 0.30 0.08 0
200 INT253379 Lep Positive_regulation of Prkaa2 1 0.39 0.19 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of cartilage development. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of cartilage development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT17881 Gene_expression of LEP 278 0.78 221.61 48.31
2 INT101483 Gene_expression of Lep 159 0.78 104.77 25.12
3 INT76123 Gene_expression of Lep 193 0.78 94.17 22.76
4 INT82434 Positive_regulation of LEP 117 0.70 95.45 20.22
5 INT9750 Positive_regulation of Rara 39 0.66 12.44 15.83
6 INT62681 Negative_regulation of LEP 93 0.59 66.97 15.77
7 INT75908 Regulation of LEP 77 0.60 60.16 15.19
8 INT73641 Regulation of Lep 45 0.62 26.2 12.59
9 INT126743 Positive_regulation of Gene_expression of LEP 61 0.66 50.02 11.17
10 INT82079 Positive_regulation of Lep 79 0.70 40 11.07
11 INT101481 Positive_regulation of Lep 81 0.69 62.59 9.95
12 INT82078 Negative_regulation of Lep 54 0.59 20.47 9.38
13 INT82082 Localization of Lep 63 0.81 26.41 8.56
14 INT75907 Binding of LEP 53 0.46 46.65 8.44
15 INT11652 Gene_expression of Rara 30 0.58 24.96 6.98
16 INT146594 Negative_regulation of Gene_expression of LEP 25 0.42 18.88 5.71
17 INT101482 Negative_regulation of Lep 53 0.54 33.59 5.65
18 INT65356 Localization of LEP 46 0.79 41.17 5.43
19 INT91338 Binding of Lep 31 0.48 26.86 5.39
20 INT102935 Regulation of Lep 31 0.60 18.47 5.24
21 INT97391 Binding of Lep 18 0.48 8.97 4.47
22 INT10374 Gene_expression of RARA 39 0.75 22.59 4.28
23 INT90890 Positive_regulation of RARA 25 0.67 9.32 4.2
24 INT163581 Localization of Lep 27 0.79 18.99 4.08
25 INT119606 Regulation of Gene_expression of LEP 17 0.45 17.96 3.75
26 INT174054 Positive_regulation of Gene_expression of Lep 25 0.69 21.3 3.72
27 INT82077 Positive_regulation of Gene_expression of Lep 32 0.70 17.9 3.5
28 INT97443 Positive_regulation of Positive_regulation of LEP 13 0.50 11.91 2.65
29 INT103487 Positive_regulation of Positive_regulation of Lep 9 0.67 4.08 2.38
30 INT82081 Regulation of Gene_expression of Lep 11 0.53 7.78 2.12
31 INT83392 Transcription of Lep 6 0.54 5.07 2.04
32 INT82083 Negative_regulation of Gene_expression of Lep 12 0.56 8.07 1.75
33 INT192092 Positive_regulation of Gene_expression of Rara 8 0.32 4.41 1.68
34 INT116022 Positive_regulation of Positive_regulation of RARA 3 0.11 0.94 1.68
35 INT67457 Binding of Rara 12 0.24 8.28 1.45
36 INT214115 Regulation of Gene_expression of Lep 9 0.61 7.37 1.44
37 INT81400 Binding of RARA 25 0.36 12.93 1.27
38 INT167270 Negative_regulation of Gene_expression of Lep 13 0.55 5.48 1.19
39 INT213465 Transcription of Lep 4 0.68 2.11 1.15
40 INT182985 Transcription of RARA 9 0.60 3.52 1.12
41 INT253813 Regulation of Negative_regulation of Lep 2 0.45 1.01 1.12
42 INT82084 Positive_regulation of Localization of Lep 11 0.70 4.65 1.11
43 INT69758 Negative_regulation of Positive_regulation of Rara 2 0.32 0.24 0.97
44 INT192090 Localization of Rara 6 0.46 4.15 0.89
45 INT48251 Regulation of Positive_regulation of Rara 2 0.33 0 0.88
46 INT117308 Negative_regulation of Localization of Lep 3 0.59 2.16 0.86
47 INT120366 Negative_regulation of Rara 2 0.35 0.15 0.86
48 INT48250 Regulation of Rara 3 0.29 2.47 0.83
49 INT333883 Positive_regulation of Positive_regulation of Lep 2 0.46 1.06 0.83
50 INT48249 Positive_regulation of Positive_regulation of Rara 2 0.26 0 0.83
51 INT212109 Localization of RARA 5 0.65 3.17 0.79
52 INT82080 Regulation of Localization of Lep 2 0.45 1.36 0.76
53 INT156533 Transcription of LEP 9 0.69 4.35 0.74
54 INT213471 Positive_regulation of Localization of Lep 4 0.48 2.65 0.74
55 INT91398 Regulation of RARA 7 0.59 5.84 0.67
56 INT101484 Regulation of Positive_regulation of Lep 3 0.45 1.68 0.61
57 INT345957 Positive_regulation of Binding of Lep 2 0.38 2.03 0.6
58 INT83391 Negative_regulation of Transcription of Lep 1 0.43 0.34 0.6
59 INT234472 Positive_regulation of Transcription of RARA 2 0.44 0.13 0.58
60 INT306798 Protein_catabolism of LEP 1 0.65 2.45 0.58
61 INT201392 Negative_regulation of RARA 8 0.30 2.99 0.5
62 INT82819 Negative_regulation of Negative_regulation of LEP 3 0.56 2.22 0.46
63 INT182966 Regulation of Gene_expression of RARA 2 0.39 0.12 0.42
64 INT102934 Positive_regulation of Regulation of Lep 2 0.50 0.55 0.42
65 INT211982 Negative_regulation of Binding of Rara 1 0.28 0.24 0.42
66 INT323765 Negative_regulation of Binding of Lep 1 0.37 0.91 0.42
67 INT187726 Positive_regulation of Localization of LEP 5 0.50 5.31 0.41
68 INT303962 Phosphorylation of Lep 2 0.80 5.2 0.31
69 INT213467 Negative_regulation of Localization of Lep 2 0.40 1.11 0.31
70 INT156534 Positive_regulation of Transcription of LEP 1 0.14 0.34 0.3
71 INT141781 Positive_regulation of Negative_regulation of LEP 1 0.46 0.37 0.29
72 INT150977 Regulation of Regulation of LEP 3 0.37 2.07 0.23
73 INT142417 Positive_regulation of Transcription of Lep 2 0.52 2.63 0.22
74 INT10375 Negative_regulation of Gene_expression of RARA 1 0.57 0.97 0.22
75 INT163816 Phosphorylation of Lep 2 0.63 2.2 0.17
76 INT333880 Protein_catabolism of Lep 1 0.65 0.34 0.17
77 INT157134 Regulation of Localization of LEP 1 0.09 0.5 0.16
78 INT333882 Regulation of Binding of Lep 1 0.45 0.07 0.16
79 INT204088 Regulation of Negative_regulation of LEP 1 0.59 1.16 0.16
80 INT300489 Negative_regulation of Binding of LEP 1 0.41 1.12 0.15
81 INT278979 Negative_regulation of Positive_regulation of LEP 2 0.40 0.81 0.14
82 INT187723 Regulation of Positive_regulation of LEP 3 0.42 2.29 0.13
83 INT192091 Regulation of Localization of Rara 1 0.04 0.67 0.13
84 INT323898 Regulation of Phosphorylation of LEP 1 0.42 1.25 0.13
85 INT323895 Phosphorylation of LEP 1 0.76 1.23 0.13
86 INT157241 Negative_regulation of Localization of LEP 5 0.56 2.1 0.12
87 INT163815 Negative_regulation of Negative_regulation of Lep 1 0.43 0.32 0.12
88 INT226984 Regulation of Transcription of Lep 1 0.27 0.3 0.11
89 INT187729 Positive_regulation of Binding of LEP 1 0.18 0.3 0.08
90 INT214071 Negative_regulation of Transcription of RARA 3 0.37 1.77 0.07
91 INT182975 Phosphorylation of RARA 2 0.58 0.23 0.07
92 INT213475 Negative_regulation of Positive_regulation of Lep 2 0.40 1.79 0.07
93 INT213466 Negative_regulation of Regulation of Lep 1 0.41 0 0.06
94 INT182990 Positive_regulation of Gene_expression of RARA 5 0.40 3.45 0
95 INT253406 Negative_regulation of Positive_regulation of Lep 2 0.41 0.74 0
96 INT150408 Regulation of Regulation of Lep 1 0.27 0 0
97 INT305226 Negative_regulation of Phosphorylation of Lep 1 0.42 1.89 0
98 INT182965 Positive_regulation of Phosphorylation of RARA 1 0.29 0 0
99 INT305239 Positive_regulation of Phosphorylation of Lep 1 0.43 1.09 0
100 INT335229 Regulation of Transcription of RARA 1 0.15 0.95 0
101 INT183002 Positive_regulation of Binding of RARA 1 0.29 1.08 0
102 INT335226 Negative_regulation of Negative_regulation of RARA 1 0.24 0.71 0
103 INT332954 Regulation of Transcription of Lep 1 0.11 1.4 0
104 INT157243 Negative_regulation of Transcription of LEP 1 0.02 0.09 0
105 INT174279 Positive_regulation of Negative_regulation of Lep 1 0.46 0.16 0
106 INT309421 Positive_regulation of Regulation of Lep 1 0.41 0.61 0
107 INT288213 Positive_regulation of Negative_regulation of Lep 1 0.47 0.06 0
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