GO:0061053

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Name somite development
Categary Process
Go Slim No
Go Link GO:0061053
Unique Molecular Interactions 126
Total Molecular Interactions 181
Total Single Events 505
Pain Genes Associated 11

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for somite development. They are ordered first by their pain relevance and then by number of times they were reported for somite development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT140985 Gli3 Regulation of Ihh 1 0.29 0.85 0.85
2 INT149899 Ihh Positive_regulation of Mmp7 1 0.04 1.69 0.65
3 INT139079 Tnip1 Negative_regulation of Ptch1 1 0.20 0.63 0.62
4 INT297340 Apoe Regulation of Binding of Smo 1 0.10 1.1 0.6
5 INT149894 Ihh Positive_regulation of Localization of Mmp14 1 0.04 2.06 0.47
6 INT113040 IHH Regulation of Gene_expression of INS 1 0.12 0.37 0.37
7 INT297342 Binding of Gnb5 and Smo 1 0.02 1.67 0.34
8 INT149897 Ihh Positive_regulation of Mmp14 1 0.03 0.93 0.33
9 INT149896 Ihh Regulation of Gene_expression of Col1a1 1 0.06 0.89 0.33
10 INT149895 Ihh Regulation of Localization of Mmp7 1 0.03 0.98 0.33
11 INT149902 Ihh Positive_regulation of SGCG 1 0.45 0.76 0.32
12 INT149898 Ihh Regulation of Localization of Mmp14 1 0.03 1.29 0.27
13 INT210798 Ihh Positive_regulation of Itgbl1 1 0.34 0 0.23
14 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19
15 INT210795 Ihh Negative_regulation of Itgb1 1 0.30 0 0.17
16 INT210782 Ihh Negative_regulation of Itgbl1 1 0.31 0 0.16
17 INT210804 Ihh Negative_regulation of Timp4 1 0.32 0 0.16
18 INT345343 PTCH1 Regulation of Negative_regulation of SMO 1 0.09 2.3 0.13
19 INT262751 Binding of PTCH1 and SMO 1 0.25 1.29 0.1
20 INT165161 Ihh Positive_regulation of Sostdc1 1 0.58 0.07 0.09
21 INT165160 Regulation of Ihh Positive_regulation of Sostdc1 1 0.23 0.07 0.09
22 INT165158 Positive_regulation of Ihh Positive_regulation of Sostdc1 1 0.42 0.07 0.09
23 INT270457 Binding of Ptch1 and Gli1 1 0.02 1.3 0.08
24 INT210788 Ihh Negative_regulation of Coro1a 1 0.02 0 0.08
25 INT270464 Binding of Shh and Smo 1 0.07 1.3 0.08
26 INT210790 Ihh Negative_regulation of Cdkn1c 1 0.30 0 0.08
27 INT290906 Shh Positive_regulation of Egfr 1 0.23 0 0.08
28 INT210787 Ihh Negative_regulation of Nr3c1 1 0.33 0 0.08
29 INT298349 HES3 Positive_regulation of Shh 1 0.12 0.14 0.07
30 INT290905 Gene_expression of Shh Positive_regulation of Gene_expression of Angpt1 1 0.14 0 0.06
31 INT262757 SMO Positive_regulation of Regulation of GLI1 1 0.34 0.6 0.04
32 INT270458 Binding of Gli1 and Smo 1 0.00 0.65 0.04
33 INT213563 Binding of Ctnnd2 and Shh 1 0.27 0.09 0.04
34 INT270459 Binding of Shh and Gli1 1 0.02 0.65 0.04
35 INT352014 Shh Positive_regulation of Gene_expression of Pax1 1 0.29 0.07 0.03
36 INT255756 Ptch1 Positive_regulation of Phosphorylation of Pik3r1 1 0.16 1.08 0.03
37 INT255733 Ptch1 Positive_regulation of Pik3r1 1 0.16 1.08 0.03
38 INT311655 Shh Positive_regulation of Gene_expression of Fgf8 1 0.31 0.18 0.03
39 INT270462 Shh Positive_regulation of Ccnd1 1 0.10 0.6 0.03
40 INT213559 Binding of Egf and Shh 1 0.17 0.07 0.03
41 INT290910 Pkm2 Negative_regulation of Shh 1 0.07 0.06 0
42 INT255758 Ptch1 Positive_regulation of Akt1 1 0.21 1.14 0
43 INT205963 GLI1 Positive_regulation of Negative_regulation of SHH 1 0.22 0.58 0
44 INT314850 Shh Regulation of Atoh7 1 0.45 0.22 0
45 INT255732 Ptch1 Positive_regulation of hs 1 0.06 1.26 0
46 INT290908 Regulation of Shh Positive_regulation of Ntn1 1 0.12 0 0
47 INT205975 Binding of PTCH1 and Smo 1 0.02 0.72 0
48 INT290911 Gene_expression of Shh Positive_regulation of Pkm2 1 0.07 0 0
49 INT290904 Shh Positive_regulation of Prkcg 1 0.26 0.06 0
50 INT290900 Prkcg Regulation of Shh 1 0.23 0 0
51 INT197794 Negative_regulation of Pthlh Regulation of Ihh 1 0.36 1.33 0
52 INT255755 Ptch1 Regulation of Positive_regulation of Ins1 1 0.05 0.28 0
53 INT205974 Smo Positive_regulation of GLI1 1 0.04 0.66 0
54 INT205958 GLI1 Positive_regulation of Gene_expression of PTCH1 1 0.35 0.57 0
55 INT205960 Binding of PTCH1 and SHH 1 0.21 0.71 0
56 INT352525 SLC25A16 Negative_regulation of SMO 1 0.00 1.1 0
57 INT290944 Shh Positive_regulation of VEGFA 1 0.04 0.05 0
58 INT270461 Shh Regulation of Gene_expression of Ptch1 1 0.48 0.07 0
59 INT255753 Ptch1 Positive_regulation of Phosphorylation of Gopc 1 0.13 1.33 0
60 INT205959 Binding of SHH and SMOX 1 0.12 0.72 0
61 INT260074 Binding of BRCA2 and PTCH1 1 0.40 0.15 0
62 INT256632 Binding of PTCH1 and Jkamp 1 0.00 2.32 0
63 INT270471 Shh Regulation of VEGFA 1 0.39 0.08 0
64 INT290898 Shh Positive_regulation of Nos2 1 0.46 0.05 0
65 INT255744 Binding of hs and Ptch1 1 0.06 1.32 0
66 INT205965 Binding of Ptch1 and Smo 1 0.03 0.72 0
67 INT270466 Ptch1 Regulation of Gene_expression of Shh 1 0.48 0.07 0
68 INT255750 Ptch1 Positive_regulation of Ins1 1 0.10 0.35 0
69 INT260073 Binding of FANCC and PTCH1 1 0.33 0.49 0
70 INT270460 Shh Positive_regulation of Gene_expression of Angpt1 1 0.04 0.08 0
71 INT260067 Binding of PTCH1 and XPA 1 0.26 1.08 0
72 INT205976 Binding of Ptch1 and SMOX 1 0.21 0.72 0
73 INT205962 Binding of PTCH1 and SMOX 1 0.14 0.72 0
74 INT255734 Ptch1 Regulation of Ins1 1 0.09 1.46 0
75 INT270470 Shh Regulation of Gene_expression of VEGFA 1 0.39 0.15 0
76 INT255760 Ptch1 Regulation of TNF 1 0.13 1.33 0
77 INT255741 Ptch1 Positive_regulation of Phosphorylation of Ins1 1 0.09 2.21 0
78 INT290907 Shh Positive_regulation of Ntn1 1 0.32 0.05 0
79 INT205977 Binding of SHH and Ptch1 1 0.31 0.71 0
80 INT205961 GLI1 Positive_regulation of Negative_regulation of PTCH1 1 0.25 0.58 0
81 INT243232 Ighmbp2 Negative_regulation of Ptch1 1 0.02 0.22 0
82 INT255749 Ptch1 Positive_regulation of Phosphorylation of Slc2a4 1 0.15 1.32 0
83 INT270469 Shh Positive_regulation of VEGFA 1 0.29 0.12 0
84 INT255735 Ptch1 Positive_regulation of Phosphorylation of Akt1 1 0.27 2.83 0
85 INT255746 Hspa1a Positive_regulation of Positive_regulation of Ptch1 1 0.19 0.99 0
86 INT255739 Ptch1 Positive_regulation of Gene_expression of Hspa1a 1 0.18 0.75 0
87 INT270468 Shh Positive_regulation of Gene_expression of VEGFA 1 0.44 0.08 0
88 INT264737 Hes1 Regulation of Shh 1 0.19 0.13 0
89 INT255759 Ptch1 Positive_regulation of Phosphorylation of hs 1 0.06 1.34 0
90 INT283711 Sox11 Regulation of 4930579C15Rik 1 0.28 0.74 0
91 INT197793 Pthlh Regulation of Ihh 1 0.22 1.32 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for somite development. They are ordered first by their pain relevance and then by number of times they were reported in somite development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT113041 Gene_expression of IHH 9 0.78 5.83 2.87
2 INT144973 Gene_expression of Shh 9 0.77 4.32 1.96
3 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77
4 INT113151 Positive_regulation of Ptch1 7 0.64 3.8 1.41
5 INT139077 Negative_regulation of Ptch1 5 0.56 5.22 1.29
6 INT183068 Gene_expression of SMO 2 0.17 0.27 1.2
7 INT140983 Gene_expression of Ihh 7 0.78 2.06 1.15
8 INT253191 Positive_regulation of Gene_expression of Shh 2 0.66 2.57 1.14
9 INT165530 Positive_regulation of Shh 4 0.69 1.21 1.05
10 INT135299 Binding of PTCH1 10 0.48 12.16 0.84
11 INT270447 Binding of Smo 2 0.07 2.61 0.78
12 INT142416 Binding of Ptch1 6 0.34 4.92 0.74
13 INT153257 Regulation of Ptch1 6 0.36 5.92 0.67
14 INT113042 Localization of IHH 1 0.70 0.77 0.61
15 INT205957 Negative_regulation of Smo 4 0.08 2.57 0.6
16 INT65919 Gene_expression of Ptch1 11 0.75 6.47 0.56
17 INT140984 Regulation of Ihh 5 0.54 2.81 0.56
18 INT206484 Localization of Shh 2 0.75 1.14 0.46
19 INT232798 Positive_regulation of Gene_expression of Shh 7 0.70 1.49 0.44
20 INT208559 Negative_regulation of Gene_expression of Shh 8 0.43 1.58 0.38
21 INT166716 Negative_regulation of Ihh 3 0.43 0.67 0.33
22 INT283698 Gene_expression of Sox11 1 0.68 4.6 0.33
23 INT356400 Transcription of Smo 1 0.02 0.05 0.3
24 INT277474 Positive_regulation of Gene_expression of SMO 1 0.11 0 0.29
25 INT216120 Negative_regulation of SMO 2 0.49 3.05 0.27
26 INT183055 Gene_expression of PTCH1 10 0.77 15.54 0.26
27 INT232795 Positive_regulation of Shh 2 0.70 3.68 0.26
28 INT149893 Positive_regulation of Gene_expression of Ihh 1 0.69 0.62 0.26
29 INT149892 Gene_expression of Ihh 1 0.77 0.61 0.26
30 INT183062 Gene_expression of SHH 12 0.65 5.28 0.21
31 INT134477 Negative_regulation of SHH 2 0.37 1.13 0.2
32 INT149888 Localization of Ihh 1 0.75 0.77 0.2
33 INT232799 Regulation of Gene_expression of Shh 3 0.27 1.04 0.16
34 INT253177 Negative_regulation of Gene_expression of Shh 2 0.55 0.63 0.16
35 INT278241 Regulation of IHH 2 0.31 1.16 0.14
36 INT253190 Localization of Shh 2 0.77 1.06 0.13
37 INT253183 Negative_regulation of Shh 8 0.55 2.13 0.12
38 INT260083 Regulation of PTCH1 11 0.27 4.46 0.09
39 INT270454 Regulation of Transcription of Ptch1 1 0.25 0.55 0.09
40 INT270442 Transcription of Shh 1 0.53 0.25 0.09
41 INT270450 Transcription of Ptch1 1 0.49 0.55 0.09
42 INT213515 Binding of Shh 8 0.37 1.92 0.08
43 INT210805 Negative_regulation of IHH 2 0.42 0.74 0.08
44 INT165148 Regulation of Binding of Ptch1 1 0.22 0.08 0.08
45 INT283695 Binding of Sox11 1 0.32 0.18 0.08
46 INT270453 Regulation of Shh 1 0.27 0.83 0.08
47 INT270452 Regulation of Gene_expression of Ptch1 1 0.25 0.25 0.08
48 INT205973 Binding of SHH 3 0.35 1.03 0.07
49 INT168919 Regulation of Regulation of Ihh 1 0.40 0.43 0.07
50 INT256862 Regulation of Shh 1 0.25 0 0.07
51 INT165154 Negative_regulation of Positive_regulation of Ptch1 1 0.34 0.09 0.07
52 INT183056 Positive_regulation of Transcription of PTCH1 1 0.28 0.46 0.07
53 INT345344 Regulation of SMO 1 0.23 1.07 0.06
54 INT255719 Phosphorylation of Ptch1 1 0.32 3.7 0.06
55 INT270445 Positive_regulation of Localization of Shh 1 0.44 0.13 0.05
56 INT283696 Localization of Sox11 1 0.65 0.37 0.05
57 INT251811 Positive_regulation of IHH 1 0.29 0.09 0.05
58 INT255726 Localization of Ptch1 1 0.33 1.74 0.05
59 INT262772 Binding of SMO 1 0.27 0.59 0.05
60 INT181793 Positive_regulation of SHH 3 0.67 2.59 0.04
61 INT183070 Transcription of PTCH1 2 0.68 0.95 0.04
62 INT208560 Negative_regulation of Shh 2 0.59 2.22 0.04
63 INT262777 Localization of SMO 1 0.59 0.6 0.04
64 INT165149 Positive_regulation of Ihh 1 0.42 0.09 0.04
65 INT253187 Negative_regulation of Transcription of Shh 1 0.41 0.55 0.03
66 INT183064 Regulation of Gene_expression of PTCH1 1 0.34 0.22 0.03
67 INT253181 Transcription of Shh 1 0.68 0.54 0.03
68 INT294470 Transcription of IHH 1 0.16 0.28 0.03
69 INT205968 Negative_regulation of PTCH1 2 0.58 2.35 0
70 INT255723 Positive_regulation of Gene_expression of Ptch1 2 0.39 1.3 0
71 INT256631 Positive_regulation of PTCH1 2 0.13 1.97 0
72 INT260088 Negative_regulation of Transcription of PTCH1 1 0.43 0.4 0
73 INT252242 Gene_expression of Smo 1 0.01 0.23 0
74 INT283699 Positive_regulation of Sox11 1 0.35 0.62 0
75 INT322888 Negative_regulation of Ihh 1 0.26 0.45 0
76 INT260089 Localization of PTCH1 1 0.70 0.37 0
77 INT290918 Negative_regulation of Positive_regulation of Shh 1 0.41 0.25 0
78 INT270455 Negative_regulation of Gene_expression of Ptch1 1 0.39 0.66 0
79 INT230972 Positive_regulation of Gene_expression of SHH 1 0.18 0.07 0
80 INT205956 Localization of Smo 1 0.06 0.71 0
81 INT290929 Binding of Shh 1 0.31 0.1 0
82 INT290927 Regulation of Positive_regulation of Shh 1 0.23 0 0
83 INT183052 Positive_regulation of Gene_expression of PTCH1 1 0.38 0.26 0
84 INT260080 Negative_regulation of Gene_expression of PTCH1 1 0.58 2.09 0
85 INT301356 Binding of Ihh 1 0.08 0.06 0
86 INT270449 Negative_regulation of Positive_regulation of Shh 1 0.43 0.24 0
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