GO:0061072

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Name iris morphogenesis
Categary Process
Go Slim No
Go Link GO:0061072
Unique Molecular Interactions 23
Total Molecular Interactions 31
Total Single Events 175
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for iris morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported for iris morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT266102 Binding of PITX2 and RS1 1 0.00 0.64 0.8
2 INT149096 PITX2 Positive_regulation of Gene_expression of Egr1 1 0.01 1.23 0.19
3 INT341818 Binding of PITX2 and Aia1 1 0.00 0.53 0.16
4 INT149095 PITX2 Positive_regulation of Casp3 1 0.00 1.51 0.15
5 INT149092 PITX2 Positive_regulation of RFFL 1 0.00 1.51 0.15
6 INT223535 Binding of HAND1 and Pax6 1 0.33 0.92 0.13
7 INT223526 Binding of Pax6 and Tcf3 1 0.33 0.92 0.13
8 INT262939 PAX6 Regulation of CDH4 1 0.02 0.97 0.08
9 INT262937 PAX6 Regulation of CDH8 1 0.03 0.98 0.08
10 INT262944 PAX6 Regulation of CDH6 1 0.03 0.97 0.08
11 INT339047 Binding of PITX2 and SNRNP70 1 0.00 0.52 0
12 INT262938 Binding of PAX6 and SIX3 1 0.13 0.9 0
13 INT339043 SNRNP70 Regulation of PITX2 1 0.00 1.42 0
14 INT250557 Binding of PITX2 and CHDH 1 0.00 2.83 0
15 INT185271 Pax6 Regulation of Psmd1 1 0.02 0 0
16 INT306339 Binding of CRX and PAX6 1 0.53 0.27 0
17 INT339044 Binding of PITX2 and SUGT1 1 0.00 2.25 0
18 INT354309 Binding of MYC and PITX2 1 0.01 0.51 0
19 INT339049 Binding of PITX2 and RENBP 1 0.00 0.27 0
20 INT262940 Regulation of Binding of PAX6 and SIX3 1 0.16 0.91 0
21 INT262942 Binding of PAX6 and SOX2 1 0.18 0.9 0
22 INT262943 Regulation of Binding of PAX6 and SOX2 1 0.17 0.91 0
23 INT283716 Neurod1 Positive_regulation of Pax6 1 0.23 0.46 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for iris morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported in iris morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT108793 Gene_expression of PITX2 12 0.75 3.91 2.89
2 INT216380 Gene_expression of PAX6 49 0.78 15.63 1.22
3 INT100154 Regulation of PITX2 5 0.60 0.48 1.15
4 INT108795 Transcription of PITX2 1 0.69 0.46 0.96
5 INT138980 Binding of PITX2 15 0.47 10.34 0.88
6 INT166727 Regulation of Gene_expression of PITX2 1 0.60 0.09 0.26
7 INT149094 Positive_regulation of Gene_expression of PITX2 1 0.05 1.23 0.19
8 INT185254 Gene_expression of Pax6 14 0.72 1.77 0.16
9 INT235781 Positive_regulation of PAX6 2 0.50 0.36 0.08
10 INT262953 Binding of PAX6 13 0.48 5.28 0.06
11 INT262951 Transcription of PAX6 6 0.72 3.33 0.06
12 INT262955 Regulation of PAX6 2 0.27 0.87 0.06
13 INT262962 Localization of PITX2 1 0.42 0.64 0.06
14 INT262963 Negative_regulation of PAX6 4 0.59 4.92 0.04
15 INT356474 Negative_regulation of PITX2 1 0.03 0.07 0.04
16 INT235783 Positive_regulation of Gene_expression of PAX6 7 0.50 1.59 0.03
17 INT206481 Transcription of Pax6 2 0.41 0.19 0.03
18 INT262954 Regulation of Transcription of PAX6 1 0.62 2.33 0.03
19 INT336419 Negative_regulation of Gene_expression of Pax6 1 0.45 0.12 0.03
20 INT250574 Positive_regulation of PITX2 2 0.02 1.79 0
21 INT291889 Negative_regulation of Pax6 2 0.45 0.39 0
22 INT262959 Localization of PAX6 2 0.75 1.65 0
23 INT262964 Negative_regulation of Binding of PAX6 1 0.43 0.44 0
24 INT324196 Positive_regulation of Gene_expression of Pax6 1 0.36 0 0
25 INT346707 Negative_regulation of Gene_expression of PAX6 1 0.37 0.5 0
26 INT291888 Regulation of Gene_expression of Pax6 1 0.33 0 0
27 INT336416 Binding of Pax6 1 0.28 0 0
28 INT235782 Negative_regulation of Positive_regulation of PAX6 1 0.24 0 0
29 INT336420 Positive_regulation of Binding of Pax6 1 0.38 0 0
30 INT291885 Regulation of Pax6 1 0.15 0 0
31 INT262956 Protein_catabolism of PAX6 1 0.66 0.14 0
32 INT262952 Regulation of Binding of PAX6 1 0.27 0.06 0
33 INT200852 Positive_regulation of Pax6 1 0.11 0 0
34 INT208927 Localization of Pax6 1 0.11 0 0
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