GO:0061077

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Name chaperone-mediated protein folding
Categary Process
Go Slim No
Go Link GO:0061077
Unique Molecular Interactions 40
Total Molecular Interactions 74
Total Single Events 387
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for chaperone-mediated protein folding. They are ordered first by their pain relevance and then by number of times they were reported for chaperone-mediated protein folding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT251170 Clu Positive_regulation of Trpv1 1 0.28 2.61 6.49
2 INT251164 Binding of Clu and Trpv1 1 0.19 0.44 2.23
3 INT251159 Binding of Clu and Positive_regulation of Trpv1 1 0.16 0 0.87
4 INT251169 Clu Regulation of Ca2 1 0.03 0.66 0.7
5 INT251166 Clu Positive_regulation of Trpc3 1 0.09 0.75 0.67
6 INT251171 Clu Positive_regulation of C6 1 0.05 0.75 0.67
7 INT251188 Clu Positive_regulation of TRPV1 1 0.01 0.23 0.64
8 INT251167 Clu Positive_regulation of Trpc6 1 0.12 0.2 0.6
9 INT251168 Clu Positive_regulation of Trpc7 1 0.15 0.2 0.59
10 INT145260 Binding of CLU and App 1 0.00 0.74 0.46
11 INT51341 Binding of Pomc and Clu 1 0.14 0 0.38
12 INT93694 Binding of Hspa8 and Ptgs1 1 0.30 0.79 0.36
13 INT269066 Binding of Hspa8 and Il6 1 0.00 0.74 0.23
14 INT224086 Binding of Agtr1a and Hspa8 1 0.00 0.1 0.19
15 INT251162 Clu Positive_regulation of Gene_expression of Trpv1 1 0.20 0.07 0.18
16 INT93693 Positive_regulation of Binding of Hspa8 and Ptgs1 1 0.31 0.38 0.17
17 INT165751 Hspa8 Positive_regulation of Protein_catabolism of Rgs9 1 0.50 0.17 0.17
18 INT224126 Binding of Hspa8 and Agtr1a 1 0.00 0.09 0.17
19 INT51344 Binding of Clu and Vtn 1 0.06 0 0.1
20 INT306510 INCENP Regulation of Gene_expression of Clu 1 0.00 1.92 0.05
21 INT284448 Il11 Positive_regulation of Hspa8 1 0.04 0.42 0.05
22 INT306505 Binding of Clu and Tnf 1 0.24 0.4 0.04
23 INT306501 Negative_regulation of Binding of Clu and Tnf 1 0.29 0.4 0.04
24 INT306500 Clu Regulation of Esr1 1 0.22 0.13 0
25 INT256825 Binding of Atp2b4 and Chordc1 1 0.02 0.27 0
26 INT306509 Binding of XRCC6 and Clu 1 0.37 0.27 0
27 INT189333 CSNK2A1 Positive_regulation of Phosphorylation of ERCC6 1 0.10 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for chaperone-mediated protein folding. They are ordered first by their pain relevance and then by number of times they were reported in chaperone-mediated protein folding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT58986 Gene_expression of Clu 17 0.77 8.35 9.61
2 INT51337 Binding of Clu 3 0.12 0.05 5.45
3 INT117121 Gene_expression of Hspa8 7 0.65 4.92 2.94
4 INT35946 Positive_regulation of Clu 12 0.69 4.92 2.73
5 INT49347 Negative_regulation of Clu 4 0.58 1.63 1.79
6 INT117122 Positive_regulation of Gene_expression of Hspa8 1 0.40 0.45 1.4
7 INT73180 Positive_regulation of Hspa8 7 0.37 3.41 1.37
8 INT35944 Regulation of Clu 4 0.20 0.15 1.3
9 INT251180 Phosphorylation of Clu 1 0.29 0.79 1.22
10 INT122988 Gene_expression of CLU 28 0.75 24.07 1.21
11 INT233561 Gene_expression of Clu 14 0.66 45.63 1.07
12 INT100273 Localization of Clu 4 0.61 0.49 0.88
13 INT70666 Positive_regulation of CLU 16 0.45 12.95 0.74
14 INT94233 Positive_regulation of Gene_expression of Clu 3 0.69 2.64 0.71
15 INT94232 Negative_regulation of Gene_expression of Clu 2 0.43 1.17 0.63
16 INT135294 Negative_regulation of Positive_regulation of Clu 1 0.37 0.35 0.59
17 INT189347 Phosphorylation of CSNK2A1 4 0.11 1.62 0.57
18 INT251182 Regulation of Phosphorylation of Clu 1 0.16 0.13 0.52
19 INT233552 Positive_regulation of Gene_expression of Clu 3 0.59 9.31 0.45
20 INT122985 Negative_regulation of Gene_expression of CLU 4 0.57 4.58 0.27
21 INT145259 Binding of CLU 1 0.03 0.84 0.27
22 INT122987 Negative_regulation of CLU 5 0.42 4.58 0.21
23 INT35945 Positive_regulation of Regulation of Clu 1 0.35 0 0.2
24 INT122984 Localization of CLU 2 0.78 2.46 0.16
25 INT122989 Positive_regulation of Localization of CLU 2 0.45 1.81 0.16
26 INT314810 Localization of Hspa8 1 0.17 0.1 0.15
27 INT122986 Positive_regulation of Gene_expression of CLU 3 0.67 2.37 0.14
28 INT233567 Positive_regulation of Clu 3 0.59 2.91 0.09
29 INT233554 Negative_regulation of Gene_expression of Clu 2 0.39 1.96 0.05
30 INT233550 Localization of Clu 2 0.69 4.52 0.05
31 INT340886 Binding of Hspa8 1 0.34 0.23 0.04
32 INT314807 Positive_regulation of Hspa8 1 0.09 0.71 0.04
33 INT256851 Regulation of Hspa8 4 0.19 3.71 0.03
34 INT161524 Regulation of Clu 4 0.38 3.18 0.03
35 INT340902 Localization of Hspa8 1 0.64 0.14 0.03
36 INT233556 Regulation of Gene_expression of Clu 2 0.33 1.45 0
37 INT49344 Negative_regulation of Transcription of Clu 1 0.35 0.07 0
38 INT348742 Gene_expression of Hspa8 1 0.38 0 0
39 INT314808 Binding of Hspa8 1 0.11 0.3 0
40 INT49345 Transcription of Clu 1 0.58 0.2 0
41 INT233564 Regulation of Positive_regulation of Clu 1 0.38 0.98 0
42 INT206738 Regulation of CLU 1 0.44 1.15 0
43 INT256852 Binding of Chordc1 1 0.27 0.15 0
44 INT354842 Protein_catabolism of CLU 1 0.28 1.6 0
45 INT306487 Binding of Clu 1 0.24 0.27 0
46 INT49348 Regulation of Transcription of Clu 1 0.50 0.13 0
47 INT318803 Regulation of Gene_expression of CLU 1 0.21 0.9 0
48 INT189359 Negative_regulation of Phosphorylation of CSNK2A1 1 0.06 0 0
49 INT233557 Transcription of Clu 1 0.45 0.77 0
50 INT318804 Negative_regulation of Localization of CLU 1 0.18 1.33 0
51 INT256858 Regulation of Chordc1 1 0.20 0.08 0
52 INT314809 Negative_regulation of Binding of Hspa8 1 0.13 0.24 0
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