GO:0061178

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Name regulation of insulin secretion involved in cellular response to glucose stimulus
Categary Process
Go Slim No
Go Link GO:0061178
Unique Molecular Interactions 47
Total Molecular Interactions 61
Total Single Events 320
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of insulin secretion involved in cellular response to glucose stimulus. They are ordered first by their pain relevance and then by number of times they were reported for regulation of insulin secretion involved in cellular response to glucose stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT147659 Prkce Positive_regulation of TRPV1 1 0.04 1.42 2.43
2 INT135582 Prok2 Positive_regulation of Localization of Prkce 1 0.06 1.02 1.87
3 INT150835 Gper Positive_regulation of Localization of Prkce 1 0.15 0.62 1.18
4 INT147660 Positive_regulation of Prkce Positive_regulation of TRPV1 1 0.04 0.69 1.12
5 INT96905 Plxna3 Regulation of Regulation of Prkce 1 0.18 0.71 1.07
6 INT109842 Prkce Positive_regulation of Localization of Trpv1 1 0.13 1.31 0.91
7 INT110518 Tnf Positive_regulation of Prkce 1 0.26 1.43 0.78
8 INT148454 Gene_expression of Inhbe Positive_regulation of Prkce 1 0.08 0.67 0.69
9 INT231533 IL4 Positive_regulation of LRP5 1 0.00 0.87 0.67
10 INT154766 Nox1 Positive_regulation of Localization of Prkce 1 0.47 0.45 0.66
11 INT112513 Binding of Prkaca and Prkce 1 0.04 0.4 0.64
12 INT112516 Binding of Prkce and Trib3 1 0.01 0.4 0.64
13 INT144129 Prkce Positive_regulation of Phosphorylation of Gja1 1 0.42 0.48 0.55
14 INT144128 Binding of Gja1 and Prkce 1 0.40 0.5 0.52
15 INT140356 Prkca Regulation of Phosphorylation of Prkce 1 0.18 0.44 0.52
16 INT150833 Esr1 Positive_regulation of Localization of Prkce 1 0.08 0.29 0.51
17 INT335888 Lrp5 Negative_regulation of Gene_expression of Tph1 1 0.22 0.15 0.21
18 INT251665 LRP5 Negative_regulation of Ache 1 0.31 0.39 0.19
19 INT134614 Prkce Regulation of Trpv1 1 0.30 0.15 0.13
20 INT110107 Acot1 Positive_regulation of Localization of Prkce 1 0.11 0 0.12
21 INT254433 Binding of Lrp5 and Sost 2 0.39 1.51 0.03
22 INT167565 Binding of ERG and LRP5 1 0.02 0.94 0.03
23 INT254434 Binding of Lrp5 and Best1 3 0.29 2.53 0
24 INT262169 Binding of Foxa2 and Nr1i2 1 0.17 0.33 0
25 INT262183 Foxa2 Positive_regulation of Gene_expression of Hmgcs2 1 0.10 0.22 0
26 INT307602 Binding of ACHE and LRP5 1 0.01 0.17 0
27 INT342385 Positive_regulation of Binding of Lrp5 and Vdr 1 0.53 0.98 0
28 INT302322 Negative_regulation of Binding of Lrp5 and SOST 1 0.16 0.26 0
29 INT308352 Binding of Ctnnd2 and Tcf7l2 1 0.15 0.74 0
30 INT269954 Sox17 Regulation of Gene_expression of Foxa2 1 0.43 0 0
31 INT269933 Foxa2 Regulation of Gene_expression of Foxj1 1 0.27 0 0
32 INT342381 Binding of Lrp5 and Vdr 1 0.55 0.97 0
33 INT169448 Binding of Prkce and Trpv4 1 0.04 0.08 0
34 INT342382 Binding of Car1 and Lrp5 1 0.40 0.9 0
35 INT302319 Binding of Lrp5 and SOST 1 0.18 0.26 0
36 INT335891 Binding of Dkk1 and Lrp5 1 0.39 0.57 0
37 INT269927 Foxa2 Regulation of Gene_expression of Scgb1a1 1 0.26 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of insulin secretion involved in cellular response to glucose stimulus. They are ordered first by their pain relevance and then by number of times they were reported in regulation of insulin secretion involved in cellular response to glucose stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT88650 Negative_regulation of Prkce 13 0.57 11.93 11.16
2 INT91948 Positive_regulation of Prkce 16 0.64 11.36 10.32
3 INT72148 Positive_regulation of Prkce 17 0.68 5.06 9.44
4 INT110104 Localization of Prkce 17 0.79 3.75 6.92
5 INT101497 Phosphorylation of Prkce 9 0.81 2.55 5.59
6 INT91946 Regulation of Prkce 6 0.44 4.13 5.46
7 INT109838 Phosphorylation of Prkce 6 0.67 5.26 4.95
8 INT60758 Gene_expression of Prkce 8 0.20 4.12 4.59
9 INT40368 Positive_regulation of LRP5 5 0.49 3.19 3.51
10 INT109840 Localization of Prkce 5 0.74 3.01 3.45
11 INT110100 Negative_regulation of Prkce 5 0.57 0.68 3.16
12 INT128184 Positive_regulation of Positive_regulation of Prkce 4 0.41 1.3 2.64
13 INT128185 Gene_expression of Prkce 4 0.69 1.39 2.23
14 INT136941 Positive_regulation of Localization of Prkce 3 0.43 1.42 2.06
15 INT124052 Binding of Prkce 2 0.06 2.52 2.03
16 INT91947 Negative_regulation of Negative_regulation of Prkce 1 0.42 0.69 1.3
17 INT110099 Positive_regulation of Localization of Prkce 4 0.68 1.3 1.25
18 INT91949 Regulation of Positive_regulation of Prkce 1 0.44 0.72 1.24
19 INT110106 Regulation of Prkce 4 0.44 0.4 1.2
20 INT110102 Negative_regulation of Localization of Prkce 3 0.49 0.17 1.13
21 INT131238 Negative_regulation of Positive_regulation of Prkce 1 0.41 0.44 1.12
22 INT135111 Regulation of Gene_expression of Prkce 1 0.51 0.15 0.96
23 INT135115 Regulation of Localization of Prkce 1 0.38 0.15 0.96
24 INT136944 Positive_regulation of Positive_regulation of Prkce 2 0.46 0.8 0.85
25 INT72334 Negative_regulation of LRP5 7 0.35 1.71 0.81
26 INT40369 Gene_expression of LRP5 8 0.55 5.63 0.74
27 INT109839 Positive_regulation of Phosphorylation of Prkce 1 0.18 1.27 0.71
28 INT154761 Positive_regulation of Gene_expression of Prkce 1 0.44 0.5 0.7
29 INT154762 Negative_regulation of Phosphorylation of Prkce 1 0.38 0.48 0.69
30 INT231558 Regulation of LRP5 2 0.24 1.02 0.68
31 INT40367 Positive_regulation of Gene_expression of LRP5 1 0.09 0 0.57
32 INT152068 Regulation of Gene_expression of Prkce 1 0.05 0.74 0.56
33 INT136942 Negative_regulation of Positive_regulation of Prkce 1 0.39 0.66 0.48
34 INT297804 Regulation of Lrp5 6 0.60 2.31 0.27
35 INT254427 Binding of Lrp5 10 0.48 5.43 0.26
36 INT334543 Negative_regulation of Positive_regulation of LRP5 1 0.23 1.81 0.25
37 INT173655 Binding of LRP5 10 0.39 3.06 0.22
38 INT140351 Binding of Prkce 2 0.28 0.32 0.22
39 INT169685 Regulation of Positive_regulation of Prkce 1 0.61 0.36 0.22
40 INT114371 Negative_regulation of Tcf7l2 1 0.05 0.7 0.2
41 INT254429 Negative_regulation of Lrp5 4 0.57 1.95 0.18
42 INT254426 Gene_expression of Lrp5 5 0.67 3.28 0.06
43 INT242172 Protein_catabolism of LRP5 1 0.64 0.06 0.04
44 INT319131 Positive_regulation of Lrp5 1 0.43 0.36 0.03
45 INT297757 Transcription of Lrp5 2 0.68 0.82 0
46 INT210256 Positive_regulation of Tcf7l2 2 0.28 1.25 0
47 INT297820 Regulation of Transcription of Lrp5 2 0.44 0.83 0
48 INT200834 Positive_regulation of Foxa2 2 0.32 0.08 0
49 INT307613 Phosphorylation of LRP5 1 0.08 0.1 0
50 INT173644 Negative_regulation of Gene_expression of LRP5 1 0.15 0.59 0
51 INT342375 Positive_regulation of Binding of Lrp5 1 0.46 0.85 0
52 INT262045 Phosphorylation of Foxa2 1 0.34 0.08 0
53 INT302465 Localization of LRP5 1 0.61 0 0
54 INT262071 Binding of Foxa2 1 0.15 0.68 0
55 INT169684 Positive_regulation of Phosphorylation of Prkce 1 0.49 0.05 0
56 INT262084 Negative_regulation of Binding of Foxa2 1 0.18 0.23 0
57 INT262125 Negative_regulation of Foxa2 1 0.18 0.08 0
58 INT307611 Positive_regulation of Phosphorylation of LRP5 1 0.05 0.1 0
59 INT269888 Gene_expression of Foxa2 1 0.65 0 0
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