GO:0061180

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Name mammary gland epithelium development
Categary Process
Go Slim No
Go Link GO:0061180
Unique Molecular Interactions 97
Total Molecular Interactions 111
Total Single Events 661
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for mammary gland epithelium development. They are ordered first by their pain relevance and then by number of times they were reported for mammary gland epithelium development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT113337 EPO Positive_regulation of JAK2 1 0.76 2.8 1.55
2 INT167944 Binding of Oprm1 and Stat5a 1 0.00 0 0.85
3 INT134049 Jak2 Positive_regulation of Gsk3b 1 0.37 0.22 0.77
4 INT134043 Jak2 Positive_regulation of Akt1 1 0.31 0.22 0.76
5 INT134051 Jak2 Positive_regulation of Stat3 1 0.44 0.22 0.76
6 INT126614 Ppyr1 Negative_regulation of Phosphorylation of Stat5a 1 0.27 0.1 0.64
7 INT126615 Binding of Oprd1 and Stat5a 1 0.28 0.07 0.61
8 INT184130 Epo Positive_regulation of Stat5a 1 0.31 0.26 0.52
9 INT184096 Il7 Positive_regulation of Stat5a 1 0.07 0.26 0.51
10 INT184132 Il2 Positive_regulation of Stat5a 1 0.09 0.26 0.51
11 INT263977 PROC Negative_regulation of JAK2 1 0.00 0.93 0.47
12 INT134048 Jak2 Regulation of Pik3cb 1 0.23 0.13 0.47
13 INT134045 Jak2 Regulation of Stat3 1 0.26 0.13 0.47
14 INT134042 Jak2 Regulation of Akt1 1 0.18 0.13 0.47
15 INT134046 Jak2 Regulation of Gsk3b 1 0.22 0.13 0.47
16 INT134050 Positive_regulation of Jak2 Regulation of Stat3 1 0.44 0.13 0.47
17 INT237414 Binding of Jak2 and Bace1 1 0.20 0.77 0.39
18 INT328828 Binding of Jak2 and Jak1 1 0.24 0 0.38
19 INT328827 Binding of Jak2 and Il6st 1 0.05 0 0.38
20 INT328820 Binding of Il6 and Jak2 1 0.09 0 0.38
21 INT303994 Il6 Positive_regulation of JAK2 1 0.03 0.41 0.37
22 INT300609 Binding of Ctnnb1 and Wnt2 1 0.02 0.25 0.37
23 INT231535 Binding of JAK2 and SOAT1 1 0.01 0.3 0.35
24 INT168202 Msx1 Negative_regulation of Gene_expression of Mc1r 1 0.21 0.49 0.35
25 INT124380 Prodh2 Regulation of Wnt2 1 0.00 0.63 0.35
26 INT242162 Binding of Ccnd1 and Wnt2 1 0.10 0.23 0.34
27 INT184084 Jak2 Positive_regulation of Stat1 1 0.33 0.3 0.33
28 INT243622 Twist1 Regulation of Jak2 1 0.30 0.2 0.32
29 INT242164 Wnt2 Positive_regulation of Localization of Apc 1 0.13 1.53 0.32
30 INT75056 Binding of MC1R and Msx1 1 0.00 0.17 0.29
31 INT325530 Positive_regulation of Gsk3b Negative_regulation of Gene_expression of Wnt2 1 0.03 0.63 0.28
32 INT168203 Binding of Mc1r and Msx1 1 0.19 0.64 0.25
33 INT240536 Il12a Positive_regulation of Jak2 1 0.10 0.74 0.21
34 INT75057 Binding of POMC and Msx1 2 0.39 0.6 0.2
35 INT299435 Rspo3 Positive_regulation of Wnt2 1 0.06 0.35 0.19
36 INT97547 KITLG Negative_regulation of Msx1 1 0.00 0.08 0.15
37 INT97542 Pomc Negative_regulation of Msx1 1 0.13 0.07 0.15
38 INT97545 Gtf3a Negative_regulation of Msx1 1 0.02 0.08 0.15
39 INT184129 Socs2 Negative_regulation of Stat5a 1 0.22 0.05 0.13
40 INT242163 Wnt2 Positive_regulation of Regulation of Apc 1 0.13 0.71 0.13
41 INT214150 Binding of Mc3r and Msx1 1 0.03 0.5 0.12
42 INT214152 Binding of Mc4r and Msx1 1 0.03 0.24 0.11
43 INT188358 Binding of Csf2 and Positive_regulation of Jak2 1 0.34 0.19 0.11
44 INT169340 Binding of UGT8 and Jak2 1 0.36 0.15 0.11
45 INT352555 DKK1 Positive_regulation of Wnt2 1 0.01 0.25 0.1
46 INT214168 Msx1 Positive_regulation of Gene_expression of DST 1 0.00 0.13 0.09
47 INT288374 Binding of MLANA and Msx1 1 0.09 0 0.08
48 INT273374 Binding of JAK2 and STAT3 1 0.24 0 0.07
49 INT273368 Negative_regulation of Binding of JAK2 and STAT3 1 0.28 0 0.07
50 INT329265 Binding of Ptk2 and Wnt2 1 0.05 1.04 0.07
51 INT242480 Ciapin1 Positive_regulation of Gene_expression of Jak2 1 0.27 1.05 0.07
52 INT273371 JAK2 Regulation of Protein_catabolism of SOCS1 1 0.01 0 0.06
53 INT200807 Jak2 Positive_regulation of Mvd 1 0.18 3.46 0.06
54 INT262214 Binding of Msx2 and Nr1i2 1 0.19 0.55 0.06
55 INT325769 Binding of EPOR and Positive_regulation of Phosphorylation of JAK2 1 0.66 0 0.06
56 INT273365 JAK2 Regulation of SOCS1 1 0.01 0 0.06
57 INT262173 Binding of Msx2 and Ep300 1 0.07 0.55 0.06
58 INT238117 Positive_regulation of STAT3 Positive_regulation of Gene_expression of JAK2 1 0.11 0 0.05
59 INT214146 Msx1 Positive_regulation of Gene_expression of Nucb2 1 0.05 0.19 0.05
60 INT321891 Dkk1 Negative_regulation of Wnt2 1 0.12 0.94 0.05
61 INT238116 STAT3 Positive_regulation of Gene_expression of JAK2 1 0.16 0 0.05
62 INT210258 Wnt2 Regulation of Gene_expression of Tff3 1 0.03 0 0.05
63 INT200821 Binding of Jak2 and Mvd 1 0.14 0.68 0.04
64 INT200813 Jak2 Positive_regulation of Akt1 1 0.26 1.46 0.03
65 INT253578 Csnk2a2 Negative_regulation of Jak2 1 0.09 0 0.03
66 INT253573 Binding of Jak2 and Pik3r1 1 0.06 0 0.03
67 INT200816 Jak2 Positive_regulation of Binding of Mvd 1 0.19 1.51 0.03
68 INT200810 Jak2 Positive_regulation of Src 1 0.29 1.46 0.03
69 INT249597 Jak2 Positive_regulation of Phosphorylation of Stat1 1 0.20 0.13 0.03
70 INT253575 Binding of Jak2 and Pik3r2 1 0.00 0 0.03
71 INT200815 Binding of Epo and Jak2 1 0.36 0.98 0.03
72 INT200822 Akt1 Regulation of Jak2 1 0.25 1.48 0.03
73 INT270938 Binding of Pick1 and Wnt2 1 0.00 0.18 0.03
74 INT353192 Stat5a Positive_regulation of Plxna3 1 0.01 0 0
75 INT340502 Agtr1a Negative_regulation of Phosphorylation of Jak2 1 0.12 2.32 0
76 INT253366 Il6 Positive_regulation of Phosphorylation of Jak2 1 0.31 0.2 0
77 INT262172 Nr1i2 Regulation of Msx2 1 0.12 0.53 0
78 INT200819 Epo Positive_regulation of Gene_expression of Jak2 1 0.49 0.91 0
79 INT300081 Binding of JAK2 and TYK2 1 0.09 1.13 0
80 INT302323 Binding of SOST and Wnt2 1 0.02 0.26 0
81 INT242165 Wnt2 Positive_regulation of Gene_expression of Fzd1 1 0.15 0.26 0
82 INT350503 Binding of HSP90AA1 and JAK2 1 0.06 1.39 0
83 INT312304 Binding of JAK2 and VEGFA 1 0.30 0.82 0
84 INT268398 Binding of LRP1 and Wnt2 1 0.01 0.36 0
85 INT335882 Dkk1 Negative_regulation of Wnt2 1 0.02 0.15 0
86 INT353190 Stat5a Positive_regulation of Cyp2c11 1 0.31 0 0
87 INT242166 Fzd1 Positive_regulation of Positive_regulation of Wnt2 1 0.13 0.24 0
88 INT241535 Abl1 Regulation of Positive_regulation of Jak2 1 0.10 0.53 0
89 INT198026 JAK2 Positive_regulation of HCC 1 0.19 1.35 0
90 INT350505 Negative_regulation of Binding of HSP90AA1 and JAK2 1 0.07 1.5 0
91 INT242159 Wnt2 Positive_regulation of Localization of Casp3 1 0.05 0.25 0
92 INT325672 Wnt2 Positive_regulation of Gopc 1 0.01 0.58 0
93 INT350504 ABL1 Negative_regulation of JAK2 1 0.20 2.18 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for mammary gland epithelium development. They are ordered first by their pain relevance and then by number of times they were reported in mammary gland epithelium development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT113161 Gene_expression of Jak2 50 0.77 42.52 4.76
2 INT124375 Gene_expression of Wnt2 67 0.56 38.03 4.67
3 INT126608 Binding of Stat5a 7 0.48 0.46 4.38
4 INT153410 Negative_regulation of Jak2 5 0.59 10.71 3.98
5 INT188047 Positive_regulation of Wnt2 51 0.58 31.41 2.94
6 INT113160 Negative_regulation of Jak2 26 0.58 20.3 2.57
7 INT126610 Phosphorylation of Stat5a 5 0.82 0.8 2.52
8 INT32920 Gene_expression of Msx1 19 0.71 4.24 2.42
9 INT113339 Binding of JAK2 6 0.40 5.31 2.4
10 INT184063 Positive_regulation of Jak2 17 0.69 10.97 2.37
11 INT118871 Negative_regulation of JAK2 15 0.57 11.4 2.16
12 INT107448 Positive_regulation of Jak2 8 0.50 5.33 1.98
13 INT126609 Positive_regulation of Phosphorylation of Stat5a 1 0.69 0.26 1.79
14 INT113340 Phosphorylation of JAK2 17 0.78 5.69 1.6
15 INT153409 Negative_regulation of Negative_regulation of Jak2 2 0.34 1.01 1.52
16 INT242153 Negative_regulation of Wnt2 19 0.49 11.87 1.37
17 INT134041 Phosphorylation of Jak2 6 0.75 3.71 1.37
18 INT126605 Negative_regulation of Binding of Stat5a 1 0.58 0.15 1.27
19 INT138726 Positive_regulation of Gene_expression of Msx1 5 0.53 1.73 1.2
20 INT205912 Negative_regulation of Gene_expression of Jak2 8 0.42 5.1 1.04
21 INT124374 Binding of Wnt2 21 0.31 10.16 0.99
22 INT198049 Positive_regulation of JAK2 16 0.58 5.35 0.96
23 INT169336 Binding of Jak2 2 0.42 1.31 0.93
24 INT134040 Regulation of Jak2 3 0.41 1.07 0.92
25 INT242152 Transcription of Wnt2 8 0.57 5.22 0.88
26 INT184027 Phosphorylation of Jak2 6 0.82 2.58 0.87
27 INT184015 Positive_regulation of Stat5a 9 0.46 3.32 0.86
28 INT134037 Positive_regulation of Phosphorylation of Jak2 1 0.46 0.25 0.86
29 INT238201 Gene_expression of JAK2 9 0.70 7.09 0.81
30 INT237408 Positive_regulation of Positive_regulation of Jak2 1 0.28 1.56 0.79
31 INT95617 Regulation of Msx1 2 0.56 1.05 0.73
32 INT113342 Positive_regulation of Phosphorylation of JAK2 2 0.66 2.58 0.72
33 INT75043 Binding of Msx1 6 0.35 2.36 0.65
34 INT126606 Negative_regulation of Stat5a 1 0.43 0.08 0.64
35 INT159942 Positive_regulation of Stat5a 3 0.41 0.95 0.61
36 INT126612 Negative_regulation of Phosphorylation of Stat5a 1 0.42 0.1 0.61
37 INT124373 Positive_regulation of Gene_expression of Wnt2 14 0.42 8.28 0.6
38 INT32921 Positive_regulation of Msx1 4 0.47 0.99 0.57
39 INT213503 Regulation of Wnt2 9 0.37 3.54 0.56
40 INT184062 Binding of Jak2 5 0.37 3.13 0.47
41 INT201524 Localization of Wnt2 14 0.62 9.24 0.46
42 INT188050 Regulation of Gene_expression of Wnt2 9 0.37 3.13 0.44
43 INT205890 Transcription of Jak2 1 0.41 0.22 0.43
44 INT247307 Negative_regulation of Msx1 3 0.22 0.11 0.42
45 INT145854 Gene_expression of Jak2 4 0.67 3.08 0.41
46 INT107462 Localization of Jak2 2 0.60 0.78 0.4
47 INT229697 Negative_regulation of Phosphorylation of Jak2 1 0.15 0.54 0.39
48 INT200786 Positive_regulation of Gene_expression of Jak2 9 0.69 6.03 0.35
49 INT205910 Negative_regulation of Positive_regulation of Jak2 1 0.33 0.26 0.35
50 INT242156 Positive_regulation of Transcription of Wnt2 2 0.42 0.23 0.34
51 INT242149 Negative_regulation of Transcription of Wnt2 2 0.35 1.8 0.33
52 INT242150 Positive_regulation of Positive_regulation of Wnt2 1 0.42 0.65 0.31
53 INT242154 Negative_regulation of Gene_expression of Wnt2 2 0.35 0.89 0.3
54 INT214128 Negative_regulation of Gene_expression of Msx1 3 0.53 1.25 0.26
55 INT303972 Positive_regulation of Gene_expression of JAK2 2 0.63 1.3 0.24
56 INT352553 Negative_regulation of Binding of Wnt2 1 0.03 0.49 0.2
57 INT268392 Regulation of Positive_regulation of Wnt2 2 0.09 0.87 0.18
58 INT184024 Binding of Stat5a 1 0.25 0.11 0.17
59 INT328811 Negative_regulation of Localization of Jak2 1 0.34 0.13 0.17
60 INT184055 Positive_regulation of Binding of Stat5a 1 0.33 0.12 0.17
61 INT200802 Regulation of Jak2 5 0.61 2.86 0.16
62 INT350667 Positive_regulation of Transcription of Stat5a 1 0.29 0.47 0.16
63 INT350637 Transcription of Stat5a 1 0.40 0.46 0.16
64 INT214127 Localization of Msx1 1 0.06 0.21 0.13
65 INT242157 Regulation of Localization of Wnt2 3 0.37 1.08 0.11
66 INT278143 Positive_regulation of Negative_regulation of Jak2 1 0.16 0.54 0.11
67 INT220368 Negative_regulation of Positive_regulation of Stat5a 1 0.34 0.46 0.11
68 INT312354 Regulation of Gene_expression of JAK2 1 0.25 1.17 0.1
69 INT200792 Regulation of Gene_expression of Jak2 5 0.61 5.69 0.09
70 INT184018 Negative_regulation of Protein_catabolism of Jak2 1 0.36 1.76 0.08
71 INT184023 Protein_catabolism of Jak2 1 0.61 1.75 0.08
72 INT350646 Negative_regulation of Positive_regulation of Stat5a 1 0.25 0.23 0.08
73 INT313905 Localization of Stat5a 1 0.21 0.33 0.08
74 INT201777 Phosphorylation of Wnt2 2 0.03 1.31 0.05
75 INT310747 Regulation of JAK2 2 0.33 1.58 0.05
76 INT238202 Negative_regulation of Localization of JAK2 1 0.09 0 0.05
77 INT238200 Localization of JAK2 1 0.16 0 0.05
78 INT184061 Negative_regulation of Stat5a 2 0.29 1.85 0.04
79 INT242148 Negative_regulation of Negative_regulation of Wnt2 1 0.35 1.06 0.04
80 INT325493 Positive_regulation of Binding of Wnt2 1 0.08 0.5 0.04
81 INT242158 Protein_catabolism of Wnt2 1 0.54 0.25 0.03
82 INT238199 Positive_regulation of Positive_regulation of JAK2 1 0.10 0 0.03
83 INT242151 Negative_regulation of Protein_catabolism of Wnt2 1 0.36 0.31 0.03
84 INT173796 Gene_expression of Stat5a 5 0.56 1.41 0
85 INT206911 Gene_expression of Msx2 4 0.71 1.26 0
86 INT200803 Phosphorylation of Stat5a 2 0.59 1.23 0
87 INT206909 Negative_regulation of Gene_expression of Msx2 2 0.53 0.29 0
88 INT206916 Positive_regulation of Gene_expression of Msx2 1 0.40 0.36 0
89 INT220772 Transcription of Msx2 1 0.46 0.08 0
90 INT322563 Negative_regulation of Positive_regulation of Wnt2 1 0.06 1.76 0
91 INT200800 Positive_regulation of Phosphorylation of Stat5a 1 0.36 0.24 0
92 INT238196 Negative_regulation of Binding of JAK2 1 0.09 0 0
93 INT202420 Transcription of Jak2 1 0.56 0.91 0
94 INT350506 Protein_catabolism of JAK2 1 0.48 1.55 0
95 INT320539 Negative_regulation of Phosphorylation of JAK2 1 0.26 0.46 0
96 INT200799 Positive_regulation of Gene_expression of Stat5a 1 0.36 0.37 0
97 INT200790 Positive_regulation of Positive_regulation of Stat5a 1 0.36 0.24 0
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