GO:0061325

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Name cell proliferation involved in outflow tract morphogenesis
Categary Process
Go Slim No
Go Link GO:0061325
Unique Molecular Interactions 71
Total Molecular Interactions 86
Total Single Events 665
Pain Genes Associated 2

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cell proliferation involved in outflow tract morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported for cell proliferation involved in outflow tract morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT141276 Negative_regulation of Il18 Negative_regulation of Gene_expression of Hand2 1 0.25 0.8 0.92
2 INT266102 Binding of PITX2 and RS1 1 0.00 0.64 0.8
3 INT222811 Binding of Hand2 and TH1L 4 0.03 8.26 0.69
4 INT338426 Binding of Hand1 and Hand2 2 0.06 2 0.46
5 INT275549 Il10 Positive_regulation of Localization of Hand2 1 0.01 1.3 0.46
6 INT275550 Hand1 Positive_regulation of Localization of Hand2 1 0.00 1.29 0.46
7 INT305853 Polk Regulation of Gene_expression of Hand2 1 0.12 0.93 0.35
8 INT300751 Binding of IGHE and Hand2 1 0.04 0 0.34
9 INT266806 Hand2 Regulation of Gene_expression of IL10 1 0.00 1.23 0.32
10 INT241139 Ighg1 Positive_regulation of Hand2 1 0.06 0.65 0.32
11 INT181435 Binding of Ccr2 and Hand2 1 0.17 1.81 0.32
12 INT181433 Hand2 Regulation of Gene_expression of Ccl2 1 0.12 0.68 0.32
13 INT266804 Hand2 Regulation of Gene_expression of IL13 1 0.00 1.23 0.32
14 INT266805 Hand2 Regulation of Gene_expression of IL4 1 0.00 1.23 0.32
15 INT253073 Il4 Positive_regulation of Hand2 1 0.10 0.59 0.31
16 INT300742 Stat6 Regulation of Hand2 1 0.01 0.06 0.3
17 INT300752 GATA3 Regulation of Hand2 1 0.01 0.06 0.3
18 INT93988 Rab8a Regulation of Hand2 1 0.09 0.78 0.3
19 INT181442 Ccl2 Positive_regulation of Localization of Hand2 1 0.26 0.63 0.29
20 INT185076 Bpifa2 Positive_regulation of Hand2 1 0.16 0.36 0.28
21 INT278209 Ciita Regulation of Hand2 1 0.36 1.53 0.28
22 INT194821 MAPK1 Regulation of Hand2 1 0.03 1.27 0.28
23 INT278216 Ciita Regulation of Gene_expression of Hand2 1 0.36 1.53 0.28
24 INT246442 Hand2 Positive_regulation of Gene_expression of Cd79a 1 0.03 0.78 0.27
25 INT305849 Polk Positive_regulation of Gene_expression of Hand2 1 0.08 0.76 0.27
26 INT226537 Hand2 Positive_regulation of IL22 1 0.02 0.86 0.26
27 INT195212 Binding of CCR4 and Hand2 1 0.03 0.46 0.21
28 INT226511 Gene_expression of Il25 Positive_regulation of Gene_expression of Hand2 1 0.01 0.95 0.2
29 INT226514 BTPs Negative_regulation of Gene_expression of Hand2 1 0.03 0.22 0.2
30 INT338767 Positive_regulation of Binding of Hand1 and Hand2 1 0.07 0.5 0.2
31 INT226510 BTPs Negative_regulation of Hand2 1 0.03 0.22 0.2
32 INT175464 Hand2 Positive_regulation of Gene_expression of Sftpd 1 0.19 1.05 0.2
33 INT228737 Rae1 Negative_regulation of Hand2 1 0.08 1.07 0.19
34 INT149096 PITX2 Positive_regulation of Gene_expression of Egr1 1 0.01 1.23 0.19
35 INT316748 IL18 Positive_regulation of Regulation of Hand2 1 0.14 1.11 0.18
36 INT329843 Il4 Regulation of Hand2 1 0.04 0.87 0.18
37 INT181457 Binding of CCL16 and Hand2 1 0.04 0.92 0.17
38 INT341818 Binding of PITX2 and Aia1 1 0.00 0.53 0.16
39 INT149095 PITX2 Positive_regulation of Casp3 1 0.00 1.51 0.15
40 INT149092 PITX2 Positive_regulation of RFFL 1 0.00 1.51 0.15
41 INT294766 Cerk Regulation of Gene_expression of Hand2 1 0.13 0.32 0.15
42 INT347012 Hand2 Positive_regulation of Il4 1 0.01 0 0.14
43 INT347015 Hand2 Regulation of Cd86 1 0.06 0 0.14
44 INT294764 Binding of Hand2 and Cerk 1 0.17 0.31 0.14
45 INT235546 Stat6 Positive_regulation of Positive_regulation of Hand2 1 0.02 0.9 0.14
46 INT347018 Cd80 Regulation of Hand2 1 0.03 0.05 0.13
47 INT347007 Cd86 Regulation of Hand2 1 0.06 0.05 0.13
48 INT296080 TGFB1 Regulation of Hand2 1 0.01 1 0.12
49 INT294760 Cerk Positive_regulation of Hand2 1 0.23 0.16 0.12
50 INT253077 Prok2 Regulation of Gene_expression of Hand2 1 0.10 0.11 0.12
51 INT294758 Regulation of Cerk Positive_regulation of Hand2 1 0.21 0.16 0.12
52 INT228746 Hspa9 Negative_regulation of Positive_regulation of Hand2 1 0.11 0.31 0.11
53 INT228760 Rae1 Negative_regulation of Positive_regulation of Hand2 1 0.08 0.31 0.11
54 INT175463 Sftpd Negative_regulation of Gene_expression of Hand2 1 0.17 0.96 0.11
55 INT263495 Hand1 Regulation of Localization of Hand2 1 0.12 0.5 0.09
56 INT263496 Hand2 Regulation of Localization of Hand1 1 0.12 0.5 0.09
57 INT201349 Binding of Hand2 and Il4 1 0.17 0.67 0.09
58 INT286298 Binding of Hand2 and Negative_regulation of Gene_expression of Il12a 1 0.07 0.3 0.07
59 INT278454 CSF2 Regulation of Hand2 1 0.02 0.66 0.05
60 INT278208 Ciita Negative_regulation of Gene_expression of Hand2 1 0.34 0.7 0.05
61 INT347020 Hand2 Regulation of Gene_expression of Cd86 1 0.08 0.19 0.04
62 INT347009 Hand2 Regulation of Gene_expression of Il4 1 0.01 0.19 0.04
63 INT339047 Binding of PITX2 and SNRNP70 1 0.00 0.52 0
64 INT305845 Polk Positive_regulation of Regulation of Hand2 1 0.08 0.34 0
65 INT339043 SNRNP70 Regulation of PITX2 1 0.00 1.42 0
66 INT184137 Binding of Socs5 and Regulation of Hand2 1 0.09 1.01 0
67 INT250557 Binding of PITX2 and CHDH 1 0.00 2.83 0
68 INT339044 Binding of PITX2 and SUGT1 1 0.00 2.25 0
69 INT354309 Binding of MYC and PITX2 1 0.01 0.51 0
70 INT339049 Binding of PITX2 and RENBP 1 0.00 0.27 0
71 INT305847 Polk Positive_regulation of Hand2 1 0.09 0.34 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cell proliferation involved in outflow tract morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported in cell proliferation involved in outflow tract morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05
2 INT84732 Positive_regulation of Hand2 81 0.69 62.07 22
3 INT112017 Regulation of Hand2 77 0.36 62.23 18.04
4 INT173505 Localization of Hand2 63 0.57 45.32 13.66
5 INT132586 Negative_regulation of Hand2 40 0.30 26.58 9.28
6 INT93045 Negative_regulation of Gene_expression of Hand2 31 0.43 25.26 9.24
7 INT93046 Positive_regulation of Gene_expression of Hand2 27 0.47 24.54 7.01
8 INT94466 Regulation of Gene_expression of Hand2 14 0.28 7.97 4.46
9 INT156131 Binding of Hand2 14 0.25 10.35 3.99
10 INT108793 Gene_expression of PITX2 12 0.75 3.91 2.89
11 INT129239 Positive_regulation of Positive_regulation of Hand2 5 0.43 2.81 1.93
12 INT100672 Transcription of Hand2 9 0.42 2.84 1.47
13 INT175452 Negative_regulation of Positive_regulation of Hand2 4 0.21 3.78 1.21
14 INT100154 Regulation of PITX2 5 0.60 0.48 1.15
15 INT235516 Positive_regulation of Localization of Hand2 4 0.36 3.04 0.97
16 INT226419 Negative_regulation of Localization of Hand2 4 0.30 3.17 0.96
17 INT108795 Transcription of PITX2 1 0.69 0.46 0.96
18 INT138980 Binding of PITX2 15 0.47 10.34 0.88
19 INT112014 Negative_regulation of Regulation of Hand2 3 0.34 2.07 0.86
20 INT271488 Negative_regulation of Negative_regulation of Hand2 3 0.18 2.36 0.67
21 INT132588 Positive_regulation of Negative_regulation of Hand2 1 0.03 0.47 0.58
22 INT325217 Regulation of Positive_regulation of Hand2 1 0.21 0.32 0.41
23 INT194745 Regulation of Regulation of Hand2 1 0.03 0.95 0.39
24 INT226424 Negative_regulation of Transcription of Hand2 1 0.08 0.66 0.37
25 INT226394 Regulation of Phosphorylation of Hand2 1 0.05 0.97 0.28
26 INT166727 Regulation of Gene_expression of PITX2 1 0.60 0.09 0.26
27 INT100671 Positive_regulation of Transcription of Hand2 2 0.36 0.81 0.23
28 INT226390 Phosphorylation of Hand2 1 0.14 0.85 0.22
29 INT263492 Positive_regulation of Regulation of Hand2 3 0.19 4.76 0.21
30 INT149094 Positive_regulation of Gene_expression of PITX2 1 0.05 1.23 0.19
31 INT284888 Regulation of Transcription of Hand2 1 0.16 0.32 0.18
32 INT262962 Localization of PITX2 1 0.42 0.64 0.06
33 INT356474 Negative_regulation of PITX2 1 0.03 0.07 0.04
34 INT192401 Positive_regulation of Binding of Hand2 1 0.08 0 0.03
35 INT250574 Positive_regulation of PITX2 2 0.02 1.79 0
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