GO:0061337

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Name cardiac conduction
Categary Process
Go Slim No
Go Link GO:0061337
Unique Molecular Interactions 29
Total Molecular Interactions 35
Total Single Events 594
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cardiac conduction. They are ordered first by their pain relevance and then by number of times they were reported for cardiac conduction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT86090 SCN5A Negative_regulation of Positive_regulation of Abat 1 0.00 0 1.25
2 INT12373 SCN5A Negative_regulation of Cpe 1 0.00 0 0.94
3 INT145646 Binding of Scn2a1 and Scn5a 1 0.36 0 0.76
4 INT67887 SCN5A Negative_regulation of INA 1 0.02 0.13 0.71
5 INT62059 Positive_regulation of SCN5A Positive_regulation of Gene_expression of FOS 1 0.01 0.42 0.66
6 INT111244 Binding of BRS3 and SCN5A 1 0.00 0.72 0.48
7 INT60456 SCN5A Regulation of Scn2a1 1 0.00 0 0.41
8 INT26577 SCN5A Positive_regulation of co 1 0.00 0 0.27
9 INT339903 Binding of SCN5A and ZGLP1 1 0.01 0.18 0.22
10 INT339901 Binding of INS and SCN5A 1 0.01 0.18 0.2
11 INT196303 Binding of SCN5A and ACCS 1 0.00 1.43 0.18
12 INT295433 Binding of PLOD1 and SCN5A 1 0.07 0.25 0.16
13 INT186240 Binding of AGRP and SCN5A 2 0.13 1.19 0.1
14 INT186246 Binding of CAT and SCN5A 1 0.03 0.47 0.1
15 INT186242 Binding of ALB and SCN5A 1 0.04 0.36 0.1
16 INT57014 PSMB1 Regulation of SCN5A 1 0.02 0 0.1
17 INT159461 SCN5A Negative_regulation of HPSE 1 0.00 0 0.07
18 INT186249 Binding of ROS1 and SCN5A 1 0.09 0.73 0.03
19 INT187672 Binding of DBT and SCN5A 1 0.00 0.2 0
20 INT272513 Binding of Mef2a and Eif2s2 1 0.03 0 0
21 INT297209 Myoz1 Regulation of Mef2a 1 0.04 0.09 0
22 INT290438 Mef2c Regulation of Mef2a 1 0.26 0.11 0
23 INT269935 Binding of Smad3 and Scn5a 1 0.13 0 0
24 INT265264 Binding of NA and SCN5A 1 0.03 0.55 0
25 INT265265 SCN5A Regulation of Gene_expression of NAV1 1 0.01 0.16 0
26 INT91242 Binding of SCN5A and PIRT 1 0.00 0 0
27 INT91245 Binding of SCN5A and EMID1 1 0.00 0 0
28 INT269918 Binding of Scn5a and Sox17 1 0.18 0.15 0
29 INT320554 Mapk14 Positive_regulation of MEF2A 1 0.26 1.31 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cardiac conduction. They are ordered first by their pain relevance and then by number of times they were reported in cardiac conduction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT3589 Positive_regulation of SCN5A 101 0.57 46.01 21.73
2 INT6782 Gene_expression of SCN5A 156 0.78 33.13 17.88
3 INT6906 Negative_regulation of SCN5A 64 0.43 20.64 7.3
4 INT101008 Gene_expression of Scn5a 5 0.75 26.93 6.06
5 INT23598 Binding of SCN5A 32 0.40 16 5.35
6 INT30209 Localization of SCN5A 24 0.72 7.95 5.35
7 INT67468 Regulation of SCN5A 27 0.44 4.4 3.47
8 INT127250 Positive_regulation of Positive_regulation of SCN5A 3 0.38 1.71 1.86
9 INT143451 Negative_regulation of Gene_expression of Scn5a 2 0.43 4.63 1.34
10 INT52589 Positive_regulation of Gene_expression of SCN5A 14 0.49 3.84 1.33
11 INT92848 Gene_expression of Scn5a 3 0.73 0.23 1.25
12 INT143450 Negative_regulation of Scn5a 3 0.43 2.71 0.88
13 INT200438 Negative_regulation of Gene_expression of SCN5A 6 0.36 1.93 0.71
14 INT52590 Transcription of SCN5A 4 0.55 0.91 0.65
15 INT252612 Regulation of Gene_expression of SCN5A 5 0.35 0.56 0.53
16 INT296806 Positive_regulation of Gene_expression of Scn5a 1 0.50 2.73 0.45
17 INT284882 Positive_regulation of Scn5a 3 0.50 1.73 0.44
18 INT163321 Protein_catabolism of SCN5A 1 0.64 0.25 0.31
19 INT284877 Transcription of Scn5a 3 0.72 1.41 0.3
20 INT137042 Negative_regulation of Transcription of SCN5A 1 0.34 0.23 0.29
21 INT92850 Transcription of Scn5a 1 0.52 0.17 0.26
22 INT92849 Positive_regulation of Gene_expression of Scn5a 1 0.49 0.17 0.26
23 INT251938 Positive_regulation of Gene_expression of MEF2A 1 0.12 0.14 0.17
24 INT251939 Gene_expression of MEF2A 1 0.18 0.14 0.16
25 INT164291 Regulation of Positive_regulation of SCN5A 2 0.38 0.73 0.15
26 INT249108 Regulation of MEF2A 1 0.17 0.28 0.14
27 INT57198 Negative_regulation of Positive_regulation of SCN5A 2 0.30 0.17 0.12
28 INT294379 Phosphorylation of Mef2a 1 0.56 0 0.1
29 INT294371 Positive_regulation of Phosphorylation of Mef2a 1 0.42 0 0.1
30 INT67512 Negative_regulation of Negative_regulation of SCN5A 1 0.01 0 0.1
31 INT284878 Regulation of Scn5a 2 0.27 1.15 0.09
32 INT249663 Negative_regulation of Phosphorylation of SCN5A 1 0.05 0.74 0.09
33 INT249661 Positive_regulation of Phosphorylation of SCN5A 1 0.06 0.74 0.09
34 INT249660 Phosphorylation of SCN5A 1 0.10 0.73 0.09
35 INT284868 Binding of Scn5a 2 0.36 0.7 0.08
36 INT290401 Gene_expression of Mef2a 1 0.64 1.81 0.07
37 INT290426 Positive_regulation of Mef2a 1 0.38 0.46 0.03
38 INT290422 Transcription of Mef2a 1 0.65 0 0.03
39 INT272480 Negative_regulation of Mef2a 2 0.40 0 0
40 INT187724 Positive_regulation of Localization of SCN5A 2 0.24 0.15 0
41 INT320531 Transcription of MEF2A 1 0.23 1.54 0
42 INT290405 Regulation of Gene_expression of Mef2a 1 0.43 0.06 0
43 INT284874 Regulation of Transcription of Scn5a 1 0.26 0.33 0
44 INT272473 Negative_regulation of Localization of Mef2a 1 0.23 0.41 0
45 INT211184 Positive_regulation of Binding of SCN5A 1 0.22 0.48 0
46 INT320540 Positive_regulation of MEF2A 1 0.17 1.32 0
47 INT272468 Localization of Mef2a 1 0.40 0.4 0
48 INT296819 Phosphorylation of Scn5a 1 0.82 0.07 0
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