GO:0070053

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Name thrombospondin receptor activity
Categary Function
Go Slim No
Go Link GO:0070053
Unique Molecular Interactions 164
Total Molecular Interactions 252
Total Single Events 1520
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for thrombospondin receptor activity. They are ordered first by their pain relevance and then by number of times they were reported for thrombospondin receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT209853 TNF Regulation of Gene_expression of CD36 1 0.61 3.41 1.59
2 INT207116 F2 Positive_regulation of F2r 5 0.12 2.16 1.16
3 INT195668 Binding of F2 and THBD 7 0.08 5.67 0.98
4 INT209852 TNF Negative_regulation of Gene_expression of CD36 1 0.43 0.61 0.98
5 INT107001 F2 Positive_regulation of PAR1 4 0.05 2.15 0.92
6 INT138602 Negative_regulation of BCL2L2 Positive_regulation of F2 1 0.00 0.67 0.92
7 INT138601 BCL2L2 Positive_regulation of F2 1 0.00 0.66 0.91
8 INT106999 F2 Positive_regulation of PAR4 3 0.06 1.83 0.72
9 INT106992 F2 Positive_regulation of PARD3 3 0.05 1.83 0.72
10 INT255260 Binding of Cd47 and Tsp1 1 0.20 1.42 0.67
11 INT150338 Binding of F2 and F2R 1 0.11 0.4 0.67
12 INT209854 IL4 Positive_regulation of Gene_expression of CD36 1 0.51 1.2 0.65
13 INT207111 F2 Positive_regulation of Pawr 2 0.07 1.38 0.64
14 INT302469 F2 Positive_regulation of Gene_expression of MMP9 1 0.01 1.82 0.62
15 INT96089 Binding of F2 and Pf4 1 0.00 1.31 0.56
16 INT96098 Binding of PPBP and F2 1 0.00 1.31 0.56
17 INT213809 F2 Positive_regulation of F2rl3 2 0.12 0.61 0.5
18 INT84515 IRF6 Positive_regulation of Gene_expression of F2 1 0.02 0.15 0.49
19 INT84520 Gene_expression of F2 Positive_regulation of F13A1 1 0.03 0.16 0.49
20 INT341622 Binding of F2 and CTRC 1 0.06 1.22 0.46
21 INT173295 F2 Positive_regulation of OR1S1 1 0.01 0.15 0.46
22 INT162043 F2 Positive_regulation of Gene_expression of OSM 1 0.44 1.13 0.41
23 INT162041 F2 Positive_regulation of Positive_regulation of FOS 1 0.13 1.14 0.41
24 INT209858 TNF Regulation of Transcription of CD36 1 0.27 0 0.4
25 INT338044 F2 Positive_regulation of Pard3 1 0.08 0.38 0.4
26 INT56876 Regulation of Binding of Cd36 and Gtpbp4 1 0.00 0 0.4
27 INT56875 Binding of Cd36 and Gtpbp4 1 0.00 0 0.4
28 INT198652 F2 Positive_regulation of Gene_expression of CD36 1 0.03 1.32 0.37
29 INT302466 Positive_regulation of F2 Positive_regulation of Gene_expression of MMP9 1 0.01 1.1 0.35
30 INT318299 Binding of F2 and PRTN3 1 0.01 1.92 0.33
31 INT312803 F2 Positive_regulation of NPEPPS 1 0.01 1.32 0.32
32 INT209855 NFE2L2 Positive_regulation of Gene_expression of CD36 1 0.27 0.72 0.32
33 INT312802 F2 Positive_regulation of Binding of NPEPPS 1 0.01 1.33 0.32
34 INT338051 Ngf Positive_regulation of Localization of F2 1 0.11 0 0.32
35 INT123397 F2 Positive_regulation of Gene_expression of PTAFR 1 0.05 0.51 0.32
36 INT334024 Ccl25 Positive_regulation of Gene_expression of CD36 1 0.31 0.36 0.31
37 INT162042 F2 Regulation of OSM 1 0.17 1.17 0.31
38 INT195669 Binding of F2 and PROC 1 0.04 1.44 0.31
39 INT162045 F2 Positive_regulation of Phosphorylation of MAPK3 1 0.30 0.99 0.3
40 INT96100 Binding of SELP and F2 1 0.01 0.67 0.29
41 INT96094 Binding of Selp and F2 1 0.00 0.67 0.29
42 INT96099 Binding of TAT and F2 1 0.01 0.68 0.29
43 INT96093 Binding of Serpinc1 and F2 1 0.00 0.68 0.29
44 INT162039 F2 Regulation of Gene_expression of OSM 1 0.29 0.94 0.29
45 INT162044 F2 Positive_regulation of Localization of FOS 1 0.32 0.9 0.28
46 INT334023 pma Positive_regulation of Gene_expression of CD36 1 0.04 0.31 0.28
47 INT162040 F2 Positive_regulation of Localization of JUN 1 0.20 0.9 0.28
48 INT252806 F2 Positive_regulation of Gene_expression of CCL2 1 0.01 0.8 0.27
49 INT338039 F2 Positive_regulation of Positive_regulation of Prkca 1 0.04 0.52 0.27
50 INT308120 Binding of F2 and F10 2 0.07 1.25 0.25
51 INT209849 TNF Positive_regulation of Gene_expression of CD36 1 0.69 0.18 0.25
52 INT252356 Binding of THBS1 and Cd47 1 0.00 0.44 0.24
53 INT198643 CD36 Positive_regulation of CADM1 1 0.01 1.07 0.24
54 INT341538 F2 Positive_regulation of F2RL1 1 0.02 0.68 0.24
55 INT63420 F2 Positive_regulation of Gene_expression of ITGA2B 1 0.14 0.45 0.23
56 INT63421 F2 Positive_regulation of Gene_expression of SELP 1 0.09 0.45 0.23
57 INT255261 Tsp1 Positive_regulation of Binding of Cd47 1 0.27 0.5 0.23
58 INT250782 APC Negative_regulation of F2 1 0.00 0.86 0.23
59 INT173292 F2 Positive_regulation of EGF 1 0.00 0.07 0.23
60 INT209856 IL1A Negative_regulation of Transcription of CD36 1 0.26 0.1 0.22
61 INT209848 TNF Positive_regulation of CD36 1 0.46 0.24 0.22
62 INT252357 Binding of THBS1 and Cd36 2 0.01 2.4 0.21
63 INT244015 Binding of Cd47 and Magt1 1 0.01 0.08 0.21
64 INT195705 Binding of SERPINC1 and SDC4 1 0.07 1.54 0.21
65 INT209851 TGFB2 Negative_regulation of Gene_expression of CD36 1 0.16 0.16 0.21
66 INT209857 IL10 Negative_regulation of Gene_expression of CD36 1 0.31 0.16 0.2
67 INT338043 F2 Positive_regulation of Localization of Prkca 1 0.04 0.1 0.2
68 INT252330 Binding of Cd36 and Cd47 2 0.10 0.72 0.19
69 INT338050 Ngf Positive_regulation of F2 1 0.11 0.25 0.18
70 INT253776 Binding of THBD and F2 1 0.00 1.15 0.18
71 INT338061 Nrtn Positive_regulation of F2 1 0.07 0.25 0.18
72 INT92269 Binding of F13A1 and F2 1 0.00 0.44 0.17
73 INT232005 Binding of Cd36 and Tsp1 2 0.25 1.81 0.16
74 INT83514 SERPINC1 Negative_regulation of F2 2 0.16 0.62 0.16
75 INT63511 F2 Negative_regulation of SERPINE2 1 0.15 0.97 0.16
76 INT231677 Binding of CD47 and THBS1 1 0.18 0 0.16
77 INT83512 F2 Negative_regulation of PLAU 1 0.27 0.57 0.16
78 INT109887 F2 Negative_regulation of F8 1 0.00 1.32 0.16
79 INT83513 Negative_regulation of SERPINC1 Negative_regulation of F2 1 0.16 0.64 0.16
80 INT83515 F2 Positive_regulation of PLAU 1 0.31 0.57 0.16
81 INT83511 F2 Negative_regulation of PRH1 1 0.01 0.6 0.15
82 INT37659 IGHG3 Negative_regulation of F2 1 0.06 0.79 0.15
83 INT240768 Binding of F2 and F13A1 1 0.07 2.25 0.15
84 INT279031 Binding of Sirpa and Cd47 1 0.09 0.77 0.15
85 INT109886 F2 Negative_regulation of Serpinc1 1 0.00 1.18 0.15
86 INT191001 F3 Positive_regulation of F2 1 0.00 0.62 0.14
87 INT338055 F2 Positive_regulation of Par2 1 0.08 0.22 0.13
88 INT107005 F2 Positive_regulation of PRSS1 1 0.00 0.28 0.13
89 INT207109 F2 Positive_regulation of Phosphorylation of Akt2 1 0.08 0.25 0.12
90 INT195710 SERPINC1 Positive_regulation of F2 1 0.08 0.69 0.11
91 INT195711 Negative_regulation of SERPINC1 Positive_regulation of F2 1 0.08 0.7 0.11
92 INT328313 Binding of CD36 and LDLR 1 0.00 0.63 0.11
93 INT328370 Binding of CD36 and Fabp1 1 0.01 0.64 0.11
94 INT8673 Binding of F2 and F8 1 0.08 0.48 0.1
95 INT8672 Positive_regulation of Binding of F2 and F8 1 0.11 0.48 0.1
96 INT8675 Positive_regulation of Binding of F2 and F3 2 0.17 0.43 0.09
97 INT8671 Binding of F2 and F3 2 0.13 0.42 0.09
98 INT298502 F10 Positive_regulation of F2 1 0.00 0.12 0.09
99 INT61217 Negative_regulation of PRTN3 Negative_regulation of F2 1 0.01 0.16 0.08
100 INT199031 Binding of ALB and F2 1 0.05 1.78 0.08
101 INT289711 Binding of F2 and Spp1 1 0.08 0.21 0.08
102 INT301613 Binding of Fabp4 and Cd36 1 0.05 0.38 0.08
103 INT289710 F2 Regulation of Spp1 1 0.04 0 0.08
104 INT253774 THBD Regulation of F2 1 0.00 0.61 0.08
105 INT195709 Negative_regulation of Binding of SERPINC1 and SDC4 1 0.09 0.24 0.08
106 INT301614 Binding of Slc27a1 and Cd36 1 0.09 0.38 0.08
107 INT231676 Binding of CD47 and ITGA5 1 0.02 0.08 0.07
108 INT191002 F2 Positive_regulation of Gene_expression of IL8 1 0.02 0.46 0.06
109 INT334027 Ccl25 Regulation of Gene_expression of CD36 1 0.14 0.24 0.05
110 INT334026 pma Regulation of Gene_expression of CD36 1 0.02 0.16 0.05
111 INT178503 Binding of Cd36 and ecs 1 0.01 0.34 0.04
112 INT269575 F2 Positive_regulation of CSH1 1 0.00 0.09 0.04
113 INT269579 F2 Positive_regulation of PAFAH2 1 0.00 0.09 0.04
114 INT262177 Nr1i2 Positive_regulation of Cd36 1 0.16 0.18 0.03
115 INT261733 F2 Regulation of COL5A2 1 0.03 0.21 0.03
116 INT229008 MIA3 Positive_regulation of Gene_expression of Cd36 1 0.02 0.49 0.03
117 INT331881 F2 Positive_regulation of F8 1 0.10 0.53 0.03
118 INT231862 F2 Positive_regulation of INCENP 1 0.00 0.86 0.03
119 INT294436 Positive_regulation of Binding of F2 and THBD 1 0.05 0.57 0
120 INT308131 PLEK Positive_regulation of F2 1 0.12 0.08 0
121 INT325904 Binding of F2 and Wbp5 1 0.01 1.22 0
122 INT283630 Cd36 Regulation of Positive_regulation of Ie 1 0.00 0 0
123 INT325898 Negative_regulation of Binding of F2 and Gopc 1 0.03 0.14 0
124 INT354566 F2 Positive_regulation of PRNP 1 0.00 0.05 0
125 INT325910 Wbp5 Positive_regulation of Positive_regulation of F2 1 0.01 0.67 0
126 INT308125 Binding of CA2 and F2 1 0.01 0.23 0
127 INT308132 Binding of RRM1 and F2 1 0.01 0 0
128 INT325902 Binding of F2 and Fgg 1 0.01 0 0
129 INT206055 F2 Positive_regulation of Gene_expression of IL6 1 0.01 1.24 0
130 INT70769 Fga Regulation of F2 1 0.00 0.65 0
131 INT277490 Binding of F2 and Thbs1 1 0.09 0 0
132 INT189561 Binding of F2 and GPER 1 0.00 0.34 0
133 INT278242 MSC Regulation of Gene_expression of Cd36 1 0.08 1.17 0
134 INT325903 Binding of F2 and Gopc 1 0.02 0.26 0
135 INT290373 Binding of Cd36 and Scarb1 1 0.11 0 0
136 INT339702 TRO Positive_regulation of CD36 1 0.08 1.06 0
137 INT261732 F2 Positive_regulation of F2R 1 0.14 0 0
138 INT65035 Fgf1 Regulation of F2 1 0.07 0.34 0
139 INT202987 Binding of F2 and ANGPTL5 1 0.07 0.07 0
140 INT325901 Binding of Dio1 and F2 1 0.01 0.63 0
141 INT325897 Negative_regulation of Binding of F2 and Wbp5 1 0.01 0.96 0
142 INT289708 Tnxa Positive_regulation of F2 1 0.00 0 0
143 INT232003 Cd36 Positive_regulation of Transcription of Fasl 1 0.10 0.66 0
144 INT59460 F2 Positive_regulation of Gene_expression of ISYNA1 1 0.06 0.14 0
145 INT325905 Wbp5 Positive_regulation of F2 1 0.01 0.37 0
146 INT283631 Positive_regulation of Binding of Cd36 and Ie 1 0.00 0 0
147 INT289709 Gopc Positive_regulation of F2 1 0.05 0 0
148 INT325899 Binding of Hps3 and F2 1 0.12 2.43 0
149 INT283629 Binding of Cd36 and Ie 1 0.00 0 0
150 INT195703 Positive_regulation of SERPINC1 Negative_regulation of F2 1 0.08 0 0
151 INT261735 Positive_regulation of F2 Positive_regulation of F2R 1 0.14 0 0
152 INT325907 Positive_regulation of Binding of F2 and Gopc 1 0.03 0.12 0
153 INT308130 Binding of F13A1 and F2 1 0.01 0.49 0
154 INT231837 F2 Regulation of Akt1 1 0.02 0.14 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for thrombospondin receptor activity. They are ordered first by their pain relevance and then by number of times they were reported in thrombospondin receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT84825 Gene_expression of CD36 121 0.78 43.73 33.23
2 INT142621 Positive_regulation of Gene_expression of CD36 38 0.70 15.18 13.4
3 INT2129 Positive_regulation of F2 83 0.70 58.95 12.63
4 INT1190 Positive_regulation of F2 53 0.70 46.41 11.64
5 INT4498 Gene_expression of F2 83 0.65 57.4 10.8
6 INT209866 Regulation of Gene_expression of CD36 27 0.60 10.04 8.42
7 INT2271 Gene_expression of F2 51 0.76 30.21 7.97
8 INT17501 Negative_regulation of F2 70 0.58 32.23 7.51
9 INT717 Regulation of F2 29 0.61 17.46 6.99
10 INT1038 Negative_regulation of F2 26 0.58 15.12 6.75
11 INT22839 Gene_expression of F2 31 0.74 15.53 5.56
12 INT164656 Negative_regulation of Gene_expression of CD36 24 0.57 6.51 5.39
13 INT20650 Positive_regulation of F2 26 0.69 15.49 5.08
14 INT9842 Binding of F2 36 0.47 22.79 4.42
15 INT26702 Transcription of CD36 17 0.70 3.56 3.49
16 INT28802 Binding of F2 15 0.47 8.8 3.47
17 INT63506 Localization of F2 21 0.77 7.53 3.41
18 INT14447 Localization of F2 20 0.79 12.77 2.67
19 INT71933 Positive_regulation of Gene_expression of F2 19 0.56 14.24 2.53
20 INT198662 Positive_regulation of CD36 14 0.68 7.73 2.36
21 INT63505 Negative_regulation of F2 18 0.57 7.4 2.2
22 INT26706 Positive_regulation of Transcription of CD36 8 0.68 3.32 2.12
23 INT94285 Negative_regulation of CD36 10 0.43 6.61 1.98
24 INT199084 Gene_expression of Cd36 31 0.53 16.94 1.94
25 INT125870 Gene_expression of CD47 3 0.76 5.11 1.71
26 INT88667 Negative_regulation of Gene_expression of F2 11 0.41 5.53 1.62
27 INT22836 Regulation of F2 9 0.59 2.3 1.49
28 INT12035 Regulation of F2 21 0.45 12.66 1.47
29 INT39444 Negative_regulation of Positive_regulation of F2 7 0.59 5.82 1.42
30 INT73938 Gene_expression of Cd36 20 0.76 12.27 1.35
31 INT195724 Gene_expression of SDC4 8 0.28 3.99 1.32
32 INT39634 Regulation of Gene_expression of F2 4 0.22 1.72 1.31
33 INT279019 Gene_expression of Cd47 3 0.56 1.43 1.31
34 INT215380 Positive_regulation of Gene_expression of Cd36 12 0.47 8.51 1.3
35 INT39443 Positive_regulation of Positive_regulation of F2 6 0.70 4.31 1.3
36 INT2270 Positive_regulation of Gene_expression of F2 6 0.21 4.23 1.26
37 INT138343 Positive_regulation of Localization of F2 5 0.41 5.06 1.24
38 INT174273 Positive_regulation of Binding of F2 3 0.08 2.99 1.02
39 INT73939 Negative_regulation of Cd36 7 0.57 6.3 0.95
40 INT252313 Positive_regulation of Cd47 4 0.22 3.95 0.87
41 INT196322 Binding of F2 18 0.15 7.74 0.83
42 INT178485 Binding of Cd36 11 0.22 6.65 0.8
43 INT138606 Negative_regulation of Positive_regulation of F2 2 0.12 0.54 0.74
44 INT231685 Binding of CD47 12 0.47 1.55 0.73
45 INT27077 Binding of CD36 4 0.37 2.14 0.72
46 INT168000 Protein_catabolism of F2 6 0.63 2.19 0.63
47 INT69098 Positive_regulation of Gene_expression of F2 5 0.66 3.79 0.58
48 INT98932 Positive_regulation of Negative_regulation of F2 1 0.04 1.06 0.58
49 INT142620 Regulation of CD36 6 0.62 0.72 0.54
50 INT243960 Binding of Cd47 2 0.18 1.06 0.51
51 INT320172 Negative_regulation of Binding of F2 2 0.41 1.92 0.5
52 INT195092 Protein_catabolism of F2 4 0.26 2.75 0.47
53 INT341584 Positive_regulation of Gene_expression of SDC4 1 0.21 1.01 0.47
54 INT67179 Negative_regulation of Binding of F2 3 0.41 2.23 0.45
55 INT300578 Negative_regulation of Cd47 1 0.24 0.17 0.44
56 INT300586 Negative_regulation of Gene_expression of Cd47 1 0.33 0.25 0.43
57 INT280670 Localization of Cd36 1 0.61 0.65 0.41
58 INT280675 Regulation of Localization of Cd36 1 0.32 0.57 0.41
59 INT162049 Phosphorylation of F2 3 0.47 0.99 0.39
60 INT69104 Positive_regulation of Localization of F2 2 0.66 0.06 0.39
61 INT126571 Positive_regulation of Cd36 3 0.41 1.19 0.38
62 INT69103 Negative_regulation of Localization of F2 2 0.56 0.48 0.37
63 INT350630 Negative_regulation of Gene_expression of Cd47 1 0.20 0.8 0.37
64 INT161436 Transcription of F2 2 0.69 1.21 0.36
65 INT350627 Gene_expression of Cd47 1 0.28 0.79 0.36
66 INT248252 Regulation of SDC4 1 0.03 0.89 0.36
67 INT10801 Localization of CD36 3 0.73 2.12 0.32
68 INT209865 Negative_regulation of Transcription of CD36 1 0.57 0.15 0.32
69 INT231687 Regulation of CD47 1 0.44 0.26 0.32
70 INT162051 Positive_regulation of Phosphorylation of F2 1 0.29 0.99 0.3
71 INT233881 Positive_regulation of Cd36 8 0.48 4.68 0.29
72 INT300582 Regulation of Gene_expression of Cd47 1 0.25 0.13 0.28
73 INT162802 Regulation of Gene_expression of F2 3 0.37 1.56 0.26
74 INT125872 Positive_regulation of Gene_expression of CD47 2 0.67 1.7 0.25
75 INT92264 Protein_catabolism of F2 2 0.03 0.98 0.23
76 INT69101 Regulation of Gene_expression of F2 1 0.43 0 0.2
77 INT20616 Localization of F2 5 0.68 1.61 0.19
78 INT108572 Positive_regulation of Binding of F2 2 0.07 0.76 0.19
79 INT99363 Negative_regulation of Gene_expression of F2 1 0.17 1.02 0.18
80 INT94854 Regulation of Negative_regulation of F2 1 0.11 0.18 0.18
81 INT35068 Transcription of F2 1 0.04 0.34 0.17
82 INT108571 Regulation of Positive_regulation of F2 1 0.07 0.17 0.17
83 INT284156 Positive_regulation of Negative_regulation of F2 1 0.01 1.71 0.15
84 INT195723 Negative_regulation of SDC4 1 0.07 0.62 0.14
85 INT231688 Localization of CD47 1 0.73 0 0.09
86 INT209861 Regulation of Transcription of CD36 1 0.44 0 0.09
87 INT200604 Positive_regulation of Binding of F2 1 0.07 0.91 0.08
88 INT199067 Negative_regulation of Gene_expression of Cd36 3 0.28 0.9 0.07
89 INT271793 Regulation of Binding of F2 1 0.03 0.46 0.05
90 INT233879 Negative_regulation of Positive_regulation of Cd36 1 0.12 0.81 0.05
91 INT196696 Negative_regulation of Cd36 5 0.18 5.5 0.04
92 INT206043 Transcription of Cd36 4 0.37 2.59 0.04
93 INT196321 Negative_regulation of Gene_expression of F2 2 0.17 1.48 0.04
94 INT195738 Binding of SDC4 1 0.05 0.38 0.04
95 INT242952 Regulation of Gene_expression of Cd36 1 0.31 0.71 0.04
96 INT142622 Positive_regulation of Regulation of CD36 2 0.47 0.14 0.03
97 INT284149 Negative_regulation of Localization of F2 1 0.05 0.13 0.03
98 INT272182 Transcription of Cd36 3 0.56 1.45 0
99 INT206050 Positive_regulation of Transcription of Cd36 3 0.32 1.72 0
100 INT272181 Positive_regulation of Transcription of Cd36 2 0.41 0.75 0
101 INT236559 Regulation of Cd36 2 0.42 0.65 0
102 INT280644 Positive_regulation of Gene_expression of Cd36 2 0.49 0.96 0
103 INT231815 Positive_regulation of Positive_regulation of F2 1 0.10 0 0
104 INT339735 Regulation of Localization of CD36 1 0.22 0.09 0
105 INT80131 Negative_regulation of Regulation of F2 1 0.05 0 0
106 INT280642 Negative_regulation of Gene_expression of Cd36 1 0.35 0.08 0
107 INT316083 Regulation of Regulation of F2 1 0.44 1.55 0
108 INT202320 Protein_catabolism of Cd36 1 0.96 0.3 0
109 INT256244 Positive_regulation of Regulation of Cd36 1 0.32 0.7 0
110 INT271827 Regulation of Cd36 1 0.18 0.94 0
111 INT339738 Positive_regulation of Localization of CD36 1 0.25 0.14 0
112 INT288533 Negative_regulation of Localization of F2 1 0.33 0.33 0
113 INT203725 Localization of Cd36 1 0.43 0.81 0
114 INT206044 Protein_catabolism of Cd36 1 0.12 0.46 0
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