GO:0070059

From wiki-pain
Jump to: navigation, search
Name apoptosis in response to endoplasmic reticulum stress
Categary Process
Go Slim No
Go Link GO:0070059
Unique Molecular Interactions 330
Total Molecular Interactions 428
Total Single Events 4709
Pain Genes Associated 13

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for apoptosis in response to endoplasmic reticulum stress. They are ordered first by their pain relevance and then by number of times they were reported for apoptosis in response to endoplasmic reticulum stress. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT156008 Bcl2 Regulation of Localization of Aifm1 1 0.17 1.92 1.47
2 INT145930 ecs Positive_regulation of Gene_expression of Bcl2 1 0.01 2.06 1.34
3 INT142202 FL Positive_regulation of Bcl2 1 0.05 0.39 0.99
4 INT112765 Binding of Nfkb1 and Bcl2 1 0.00 1.37 0.91
5 INT166634 Binding of Bcl2 and Becn1 1 0.20 0.5 0.86
6 INT150864 RYBP Positive_regulation of Positive_regulation of Bcl2 1 0.01 0.66 0.86
7 INT218935 Cyp3a23/3a1 Regulation of Bcl2 1 0.00 1.08 0.74
8 INT320633 Positive_regulation of MAPK1 Regulation of BCL2 1 0.04 1.21 0.7
9 INT151559 Atp2a1 Negative_regulation of Positive_regulation of CASP3 1 0.06 0.68 0.66
10 INT296793 Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.75 0.65
11 INT296790 Tlr9 Regulation of Bax 1 0.14 0.76 0.65
12 INT296791 Positive_regulation of Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.8 0.65
13 INT296785 Tlr9 Regulation of Bcl2 1 0.19 0.76 0.65
14 INT112699 Bid Regulation of Bax 1 0.25 0.51 0.61
15 INT151558 ERLEC1 Regulation of Atp2a1 1 0.00 0.64 0.53
16 INT151557 NARG2 Regulation of Atp2a1 1 0.01 0.64 0.53
17 INT302839 MIR15A Negative_regulation of Bcl2 1 0.15 1.41 0.47
18 INT41174 Bak1 Regulation of Localization of Prl 1 0.02 0 0.46
19 INT238639 Cd86 Negative_regulation of Negative_regulation of Bcl2 1 0.01 0.97 0.46
20 INT112772 Binding of Bcl2 and SGSM3 1 0.02 0.69 0.45
21 INT238638 Gopc Negative_regulation of Gene_expression of Bax 1 0.04 0.85 0.45
22 INT116609 Lnpep Negative_regulation of Bcl2 1 0.05 0.62 0.43
23 INT116606 Lnpep Regulation of Gene_expression of Bcl2 1 0.07 0.62 0.43
24 INT116607 Lnpep Negative_regulation of Gene_expression of Bcl2 1 0.10 0.62 0.43
25 INT309143 Dlat Positive_regulation of Bcl2 1 0.06 1.04 0.42
26 INT309152 Dlat Positive_regulation of Gene_expression of Bcl2 1 0.04 1.05 0.42
27 INT235878 Creb1 Positive_regulation of Gene_expression of Bcl2 1 0.05 0.17 0.38
28 INT155062 Csf2 Positive_regulation of Transcription of Bcl2 1 0.31 2.91 0.36
29 INT264555 IL15 Positive_regulation of Gene_expression of BCL2 1 0.02 0.92 0.35
30 INT155061 Stat3 Negative_regulation of Bax 1 0.22 3.71 0.34
31 INT269962 Bcl2 Negative_regulation of Bcl2l11 1 0.15 2.14 0.34
32 INT155060 Stat3 Negative_regulation of Bcl2 1 0.21 3.7 0.33
33 INT242398 Cyp19a1 Positive_regulation of Bcl2 1 0.00 1.28 0.3
34 INT218928 Cyp3a23/3a1 Regulation of Transcription of Bcl2 1 0.00 0.56 0.28
35 INT260837 NRP2 Negative_regulation of Negative_regulation of Bcl2 1 0.00 0.9 0.28
36 INT172905 Binding of Bad and Bcl2 3 0.08 6.46 0.27
37 INT237927 BCL2 Positive_regulation of BAX 2 0.24 2.22 0.26
38 INT237928 BCL2 Positive_regulation of FAS 1 0.02 1.41 0.26
39 INT272157 Gh1 Negative_regulation of Bcl2 1 0.23 1.2 0.26
40 INT272158 Gh1 Regulation of Bcl2 1 0.15 1.2 0.26
41 INT107189 Atp2a2 Negative_regulation of Atp2a1 1 0.27 0 0.26
42 INT237925 BCL2 Positive_regulation of Protein_catabolism of PARP1 1 0.02 1.42 0.26
43 INT260840 NRP2 Positive_regulation of Gene_expression of Bcl2 1 0.00 0.85 0.24
44 INT302170 PTGER2 Positive_regulation of Gene_expression of BCL2 1 0.04 3.76 0.23
45 INT155063 Csf2 Negative_regulation of Gene_expression of Bax 1 0.27 1.46 0.18
46 INT176133 AKT1 Regulation of BCL2 2 0.12 1.84 0.17
47 INT285026 Bak1 Regulation of Bcl2 1 0.09 0.71 0.17
48 INT285022 Regulation of Bak1 Regulation of Bcl2 1 0.09 0.71 0.17
49 INT155066 Csf2 Negative_regulation of Bax 1 0.12 1.89 0.17
50 INT349475 Regulation of Bax Regulation of Bcl2 1 0.07 1.35 0.17
51 INT155233 TXNIP Regulation of BCL2 1 0.23 0.15 0.17
52 INT285024 Bcl2 Regulation of Bak1 1 0.09 0.71 0.17
53 INT229203 Binding of Bcl2 and Cyp2c11 1 0.36 1.2 0.17
54 INT155068 Csf2 Negative_regulation of Bcl2 1 0.12 1.88 0.17
55 INT347445 CD99 Positive_regulation of BCL2 1 0.17 0.95 0.16
56 INT336891 Epo Negative_regulation of Transcription of Bax 1 0.10 0.68 0.16
57 INT292750 Akt1 Positive_regulation of Bcl2 1 0.01 1.67 0.15
58 INT349476 Bax Regulation of Bcl2 1 0.07 1.33 0.15
59 INT311666 Binding of BCL2 and TP53 1 0.19 1.26 0.14
60 INT95104 TGFBR2 Positive_regulation of BCL2 1 0.08 0.61 0.14
61 INT273040 Vip Regulation of Bax 1 0.23 1.69 0.13
62 INT309139 Edc4 Positive_regulation of Bcl2 1 0.03 0.12 0.13
63 INT148594 Binding of BCL2 and CD34 1 0.39 1.17 0.13
64 INT309142 Edc4 Regulation of Bcl2 1 0.02 0.12 0.13
65 INT246016 Negative_regulation of Timp1 Negative_regulation of Gene_expression of Bcl2 1 0.03 1.07 0.13
66 INT273041 Adcyap1 Regulation of Bax 1 0.21 1.69 0.13
67 INT342311 Binding of Tp53 and Positive_regulation of Gene_expression of BCL2 1 0.08 1.25 0.13
68 INT348542 BCL2 Negative_regulation of NLRP1 1 0.07 2.02 0.13
69 INT246017 Timp1 Negative_regulation of Gene_expression of Bcl2 1 0.03 1.07 0.13
70 INT172899 Binding of Bcl2 and Bcl2l1 3 0.02 5.54 0.12
71 INT226192 Protein_catabolism of Bax Positive_regulation of Gtf3a 1 0.00 0.53 0.12
72 INT178101 EDN1 Negative_regulation of Phosphorylation of BCL2 1 0.03 1 0.12
73 INT305194 Bcl2 Positive_regulation of Epo 1 0.06 0.29 0.12
74 INT273063 Negative_regulation of Fas Negative_regulation of Positive_regulation of Bcl2 1 0.01 0.72 0.11
75 INT285030 Binding of Bax and Slc25a4 1 0.03 0.84 0.11
76 INT221684 Binding of Bcl2 and FRTS 1 0.01 1.19 0.11
77 INT265888 BCL2 Regulation of Gene_expression of BAD 1 0.04 1.08 0.1
78 INT265890 BCL2 Regulation of Gene_expression of BAX 1 0.04 1.08 0.1
79 INT239643 Binding of BCL2 and BCL2L11 3 0.16 2.26 0.09
80 INT282094 Apoa2 Negative_regulation of BCL2 1 0.06 1.15 0.09
81 INT275183 Bad Positive_regulation of Gene_expression of Bcl2 1 0.08 0.63 0.09
82 INT265887 IGF1 Negative_regulation of BCL2 1 0.09 1.02 0.09
83 INT294637 Bcl2a1a Positive_regulation of Gene_expression of Bcl2 1 0.15 0.97 0.09
84 INT204300 Bcl2 Negative_regulation of Positive_regulation of Bak1 1 0.02 1.13 0.09
85 INT350908 Binding of Bcl2 and Twist1 1 0.04 1.9 0.08
86 INT201456 Hmox1 Positive_regulation of Gene_expression of Bcl2 1 0.06 0.74 0.08
87 INT302290 Birc5 Regulation of BAK1 1 0.21 1.22 0.07
88 INT204301 Positive_regulation of Hrk Positive_regulation of Positive_regulation of Bak1 1 0.00 1.17 0.07
89 INT302131 Negative_regulation of SOD2 Regulation of BAK1 1 0.09 1.22 0.07
90 INT302289 Negative_regulation of Birc5 Regulation of BAK1 1 0.20 1.22 0.07
91 INT285025 Bnip3 Positive_regulation of Bak1 1 0.11 0.78 0.07
92 INT204299 Bcl2 Negative_regulation of Localization of Aifm1 1 0.06 1.22 0.07
93 INT285032 Bnip3 Positive_regulation of Bax 1 0.28 0.77 0.07
94 INT340401 Positive_regulation of Bax Positive_regulation of Binding of Hrk 1 0.01 0.79 0.07
95 INT302128 SOD2 Regulation of BAK1 1 0.09 1.22 0.07
96 INT297733 Cbr1 Regulation of Gene_expression of Bcl2 1 0.05 0.94 0.07
97 INT340395 Binding of Bax and Tg(CAG-EGFP)D4Nagy 1 0.02 0.43 0.07
98 INT302147 PTGER2 Positive_regulation of BAK1 1 0.06 2.08 0.06
99 INT302177 PTGER2 Positive_regulation of BCL2 1 0.04 2.08 0.06
100 INT352299 Regulation of Binding of BCL2 and VIM 1 0.10 1.07 0.06
101 INT352298 Binding of BCL2 and VIM 1 0.09 1.06 0.06
102 INT302138 PTGER2 Positive_regulation of Gene_expression of BAK1 1 0.06 2.08 0.06
103 INT341375 Sod2 Regulation of Bcl2 1 0.08 1.96 0.05
104 INT190824 Binding of Cl and Bcl2 1 0.02 1.4 0.05
105 INT333252 Positive_regulation of Binding of Bcl2 and Mcl1 1 0.03 0.88 0.04
106 INT268664 Ptger2 Positive_regulation of Bcl2 1 0.02 0.9 0.04
107 INT333245 Binding of Bcl2 and Bcl2l11 1 0.03 0.87 0.04
108 INT268666 Ptger2 Positive_regulation of Gene_expression of Bcl2 1 0.02 0.9 0.04
109 INT340394 Binding of Bax and Bbc3 1 0.01 0.36 0.04
110 INT204298 Bid Positive_regulation of Binding of Bak1 1 0.05 0.57 0.04
111 INT350905 Binding of Bcl2 and Pcsk4 1 0.03 0.96 0.04
112 INT333253 Binding of Bcl2 and Mcl1 1 0.02 2.14 0.04
113 INT306527 Binding of Htt and Aifm1 1 0.20 0.82 0.04
114 INT250025 Map3k1 Positive_regulation of Regulation of Bcl2 1 0.01 1.1 0.04
115 INT172902 Binding of Bax and Bcl2 5 0.30 3.19 0.03
116 INT192164 Binding of BAK1 and BCL2 3 0.04 2.8 0.03
117 INT192167 Negative_regulation of Binding of BAK1 and BCL2 2 0.05 1.89 0.03
118 INT192165 Binding of BAK1 and BCL2L1 2 0.06 1.35 0.03
119 INT288538 Il2 Positive_regulation of Gene_expression of Bcl2 1 0.04 1.96 0.03
120 INT192166 Negative_regulation of Binding of BAK1 and BCL2L1 1 0.05 1.06 0.03
121 INT297737 Cbr1 Positive_regulation of Bax 1 0.06 0.53 0.03
122 INT224682 Mcl1 Regulation of Bak1 1 0.01 1.09 0.03
123 INT217148 MIR21 Regulation of BCL2 1 0.32 0.98 0.03
124 INT101159 Gene_expression of Bcl2 Positive_regulation of Gene_expression of CHAT 1 0.31 0.96 0.03
125 INT229204 Olr1254 Negative_regulation of Gene_expression of Bcl2 1 0.02 0.18 0.03
126 INT333259 Bcl2 Regulation of Bax 1 0.03 0.32 0.03
127 INT172894 Negative_regulation of Lox Negative_regulation of Gene_expression of Bcl2 1 0.03 1.12 0.03
128 INT220445 Bcl2 Negative_regulation of Positive_regulation of Casp9 1 0.01 1.37 0.03
129 INT224689 Binding of Bak1 and Mcl1 1 0.01 1.09 0.03
130 INT224676 Binding of Bax and Mcl1 1 0.01 1.09 0.03
131 INT333249 Cxcl12 Positive_regulation of Positive_regulation of Bak1 1 0.30 0.32 0.03
132 INT224690 Mcl1 Regulation of Bax 1 0.00 1.09 0.03
133 INT333262 Bcl2 Regulation of Bak1 1 0.04 0.31 0.03
134 INT341376 Sod2 Regulation of Bax 1 0.09 0.99 0.03
135 INT282995 Binding of Bcl2 and Becn1 21 0.03 9.8 0
136 INT283013 Binding of Bak1 and Bcl2 4 0.06 1.03 0
137 INT185852 Binding of BAK1 and BAX 3 0.29 2.5 0
138 INT178861 Binding of BAX and BCL2 3 0.27 3.07 0
139 INT172906 Binding of Bax and Bcl2l1 2 0.16 2.03 0
140 INT292454 Binding of BAD and BCL2 2 0.03 1.73 0
141 INT144032 STAT3 Regulation of BCL2 2 0.07 0.86 0
142 INT217150 MIR16-2 Regulation of BCL2 2 0.09 1.89 0
143 INT217137 MIR15B Regulation of BCL2 2 0.15 1.88 0
144 INT185851 BID Positive_regulation of BAK1 1 0.43 0.73 0
145 INT295047 Binding of Bcl2 and Nr4a1 1 0.04 0.96 0
146 INT254089 EPO Regulation of Gene_expression of Bcl2 1 0.03 0.63 0
147 INT285031 Binding of Bcl2 and Bcl2l1 1 0.27 0.1 0
148 INT321406 VEGFA Regulation of BCL2 1 0.01 0.75 0
149 INT295046 Bcl2 Regulation of Gene_expression of Nr4a1 1 0.02 0.92 0
150 INT292503 Mlph Regulation of Gene_expression of BCL2 1 0.00 0.4 0
151 INT220456 Binding of VCAN and BAG6 1 0.01 3.46 0
152 INT253474 Positive_regulation of Prkaca Positive_regulation of Gene_expression of Bcl2 1 0.04 1.27 0
153 INT285029 Binding of Bax and Bcl2l1 1 0.25 0.1 0
154 INT330047 Binding of Bax and Bcl2l11 1 0.13 0.62 0
155 INT191058 Binding of Bcl2 and Positive_regulation of Gene_expression of Bax 1 0.21 0.49 0
156 INT333258 Gene_expression of Cxcl12 Positive_regulation of Positive_regulation of Bak1 1 0.15 0.55 0
157 INT333688 Trp53 Positive_regulation of Bcl2 1 0.45 2.51 0
158 INT254707 Positive_regulation of Map2k1 Regulation of Gene_expression of BAK1 1 0.05 0.67 0
159 INT322658 Binding of Bak1 and Prdm8 1 0.02 0.89 0
160 INT348531 Binding of BCL2 and BECN1 1 0.06 0.43 0
161 INT221240 Akt1 Positive_regulation of Phosphorylation of Bcl2 1 0.00 0.89 0
162 INT191062 Esr1 Regulation of Gene_expression of Bcl2 1 0.12 0.73 0
163 INT242483 Negative_regulation of Ciapin1 Negative_regulation of Positive_regulation of Bax 1 0.17 1.76 0
164 INT267255 Bcl2 Positive_regulation of Gene_expression of Ptprj 1 0.04 0.63 0
165 INT136914 Mapk8 Positive_regulation of Localization of Bax 1 0.51 0.12 0
166 INT191061 Akt1 Positive_regulation of Bcl2 1 0.41 0.33 0
167 INT283003 Igkv1-131 Regulation of Binding of Bcl2 1 0.06 0 0
168 INT280566 Binding of ARAF and BCL2 1 0.02 0.69 0
169 INT302137 Binding of BAD and BAK1 1 0.07 0.93 0
170 INT283009 Binding of Bcl2 and Pdss2 1 0.03 0.56 0
171 INT100424 Bcl2 Regulation of Pcbd1 1 0.14 0.06 0
172 INT202507 Nfasc Positive_regulation of Gene_expression of Bcl2 1 0.10 0.7 0
173 INT322664 Prdm8 Positive_regulation of Gene_expression of Bax 1 0.01 1.1 0
174 INT283000 Negative_regulation of Binding of Bcl2 and Becn1 1 0.03 0.71 0
175 INT315060 PAR4 Regulation of BCL2 1 0.53 0.48 0
176 INT327972 Negative_regulation of BCL2 Positive_regulation of BAX 1 0.22 0.82 0
177 INT285028 Binding of Bcl2 and Bax 1 0.32 0.1 0
178 INT268516 Gene_expression of MIR16-2 Positive_regulation of Gene_expression of BCL2 1 0.00 1.15 0
179 INT335953 Binding of BCL2 and Bad 1 0.14 0.37 0
180 INT198021 Binding of BCL2 and MCL1 1 0.17 2.88 0
181 INT331231 Binding of Bcl2 and Mapk8 1 0.01 0.77 0
182 INT283011 Binding of Bcl2 and Igkv1-131 1 0.05 0.8 0
183 INT296670 Binding of Bcl2 and Vim 1 0.00 1.31 0
184 INT191065 Binding of Bcl2 and Negative_regulation of Phosphorylation of Akt1 1 0.22 1.02 0
185 INT292458 Negative_regulation of Binding of BAD and BCL2 1 0.01 0.81 0
186 INT327977 TNFRSF11A Regulation of BCL2 1 0.05 0.67 0
187 INT337707 Naf1 Regulation of Gene_expression of Bcl2 1 0.11 0.57 0
188 INT229821 Fos Positive_regulation of Bax 1 0.15 0.27 0
189 INT322668 Prdm8 Positive_regulation of Gene_expression of Bak1 1 0.02 1.1 0
190 INT309517 Binding of Bax and Xrcc6 1 0.15 0.5 0
191 INT201761 BIK Positive_regulation of Positive_regulation of Bax 1 0.01 0.43 0
192 INT191059 Bcl2 Positive_regulation of Localization of Il12a 1 0.16 0.77 0
193 INT202503 Gtf3a Positive_regulation of Positive_regulation of Bcl2 1 0.02 0.35 0
194 INT330052 Binding of Bax and Bid 1 0.15 0.62 0
195 INT286030 Creb1 Regulation of Transcription of Bcl2 1 0.07 0.34 0
196 INT322662 Binding of Bax and Pbrm1 1 0.08 0.9 0
197 INT172908 Binding of Bad and Bax 1 0.01 1.34 0
198 INT330057 Bid Positive_regulation of Bax 1 0.19 0.62 0
199 INT327403 Bcl2 Positive_regulation of Localization of Mmp2 1 0.19 0.93 0
200 INT189673 BCL2 Positive_regulation of Transcription of TERT 1 0.09 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for apoptosis in response to endoplasmic reticulum stress. They are ordered first by their pain relevance and then by number of times they were reported in apoptosis in response to endoplasmic reticulum stress. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03
2 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38
3 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73
4 INT100423 Gene_expression of Bax 141 0.75 98.43 24.48
5 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46
6 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37
7 INT109511 Gene_expression of Bax 133 0.78 113.22 14.36
8 INT80222 Negative_regulation of Bcl2 82 0.58 69.16 13.18
9 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63
10 INT102110 Positive_regulation of Gene_expression of Bax 42 0.67 35.77 9.51
11 INT102106 Positive_regulation of Bax 48 0.67 30.62 9.28
12 INT80037 Gene_expression of BAK1 58 0.75 39.49 9.08
13 INT70017 Positive_regulation of BCL2 87 0.67 66.62 8.68
14 INT86672 Negative_regulation of Bcl2 50 0.53 34.16 8.37
15 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27
16 INT80220 Positive_regulation of Bcl2 71 0.58 57.73 7.86
17 INT77306 Negative_regulation of Gene_expression of Bcl2 46 0.58 38.05 7.71
18 INT91445 Regulation of Bcl2 50 0.56 38.8 7.41
19 INT102107 Negative_regulation of Gene_expression of Bax 30 0.57 29.48 7.33
20 INT93101 Regulation of Gene_expression of Bcl2 26 0.62 18.45 6.71
21 INT84685 Regulation of BCL2 67 0.60 72.96 6.65
22 INT98837 Positive_regulation of Bax 72 0.61 63.14 6.41
23 INT100422 Negative_regulation of Gene_expression of Bcl2 46 0.58 28.86 5.7
24 INT145929 Regulation of Bax 20 0.60 18.12 5.35
25 INT70613 Negative_regulation of Gene_expression of BCL2 48 0.59 38.91 5.22
26 INT73262 Negative_regulation of BCL2 67 0.57 61.01 5.07
27 INT109513 Positive_regulation of Gene_expression of Bax 37 0.67 29.52 5.06
28 INT99504 Negative_regulation of Bax 19 0.56 8.89 4.44
29 INT101957 Transcription of Bcl2 30 0.69 16.57 4.3
30 INT103345 Positive_regulation of Gene_expression of BAK1 10 0.57 6.4 4.19
31 INT123752 Regulation of Bax 19 0.60 16.45 4
32 INT112692 Localization of Bax 31 0.80 20.97 3.98
33 INT105882 Phosphorylation of Bcl2 11 0.59 8.15 3.73
34 INT164540 Localization of Aifm1 15 0.46 13.87 3.65
35 INT137634 Localization of Aifm1 17 0.80 11.8 3.45
36 INT109403 Regulation of Gene_expression of BCL2 31 0.60 31.22 3.4
37 INT81642 Regulation of Gene_expression of Bcl2 20 0.44 16.93 3.19
38 INT64234 Regulation of Bcl2 41 0.54 31.88 3.16
39 INT105884 Binding of Bcl2 19 0.35 15.67 3
40 INT74293 Positive_regulation of BAK1 13 0.60 14.13 2.73
41 INT195005 Positive_regulation of Aifm1 11 0.29 7.92 2.46
42 INT102146 Phosphorylation of Bax 4 0.66 3.48 2.35
43 INT151574 Gene_expression of Aifm1 5 0.62 3.63 2.34
44 INT147349 Localization of Bcl2 13 0.65 7.83 2.31
45 INT142677 Negative_regulation of Positive_regulation of Bcl2 4 0.36 3.09 2.24
46 INT154970 Localization of Bax 15 0.74 11.12 2.11
47 INT86671 Negative_regulation of Positive_regulation of Bcl2 6 0.57 3.83 2.03
48 INT98836 Transcription of Bax 6 0.69 5.04 1.96
49 INT134442 Transcription of Bax 14 0.67 7.6 1.9
50 INT135540 Negative_regulation of Bax 16 0.48 11.8 1.89
51 INT101108 Localization of Bcl2 16 0.72 11.68 1.86
52 INT105883 Positive_regulation of Phosphorylation of Bcl2 8 0.32 5.67 1.86
53 INT134443 Binding of Bax 10 0.47 5.62 1.84
54 INT156005 Positive_regulation of Gene_expression of Aifm1 1 0.36 1.56 1.75
55 INT104883 Positive_regulation of Positive_regulation of Bax 4 0.45 4.05 1.74
56 INT101958 Positive_regulation of Transcription of Bcl2 4 0.50 2.22 1.65
57 INT137513 Negative_regulation of Positive_regulation of BCL2 6 0.35 5.3 1.62
58 INT103967 Negative_regulation of Gene_expression of BAK1 8 0.42 7.02 1.54
59 INT62800 Regulation of BAK1 7 0.41 10.12 1.47
60 INT146785 Positive_regulation of Localization of Bax 7 0.69 6.16 1.47
61 INT109512 Negative_regulation of Gene_expression of Bax 12 0.42 8.04 1.44
62 INT141037 Positive_regulation of Aifm1 3 0.45 3.32 1.38
63 INT164541 Negative_regulation of Localization of Aifm1 3 0.27 4.51 1.38
64 INT112695 Negative_regulation of Protein_catabolism of Bax 3 0.36 1.72 1.3
65 INT142017 Positive_regulation of Positive_regulation of BAK1 2 0.52 1.74 1.3
66 INT195013 Positive_regulation of Localization of Aifm1 1 0.27 4.18 1.29
67 INT101107 Positive_regulation of Localization of Bcl2 3 0.48 3.13 1.28
68 INT154969 Positive_regulation of Localization of Bax 4 0.64 3.42 1.27
69 INT37646 Negative_regulation of Aifm1 2 0.47 1.28 1.26
70 INT112693 Protein_catabolism of Bax 5 0.74 3.17 1.2
71 INT141189 Negative_regulation of Transcription of Bax 1 0.41 1.42 1.14
72 INT172855 Binding of Bcl2 37 0.32 23.41 1.09
73 INT70021 Localization of BCL2 23 0.74 21.6 1.09
74 INT220465 Binding of BAG6 7 0.30 6.41 1.07
75 INT141036 Negative_regulation of Aifm1 1 0.00 1.26 1.07
76 INT93094 Gene_expression of Bak1 13 0.52 13.94 1.02
77 INT175507 Regulation of Gene_expression of Bax 13 0.50 10.91 0.95
78 INT135542 Positive_regulation of Bak1 17 0.43 16.12 0.88
79 INT151115 Regulation of Regulation of Bcl2 4 0.21 4.12 0.88
80 INT92117 Phosphorylation of BCL2 26 0.80 9.93 0.86
81 INT144697 Regulation of Gene_expression of Bax 8 0.37 9.5 0.81
82 INT70019 Binding of BCL2 25 0.47 17.55 0.79
83 INT195007 Positive_regulation of Gene_expression of Aifm1 1 0.40 4.75 0.79
84 INT195016 Gene_expression of Aifm1 8 0.45 5.92 0.78
85 INT109404 Transcription of BCL2 6 0.69 4.49 0.77
86 INT124844 Regulation of Positive_regulation of Bcl2 3 0.43 2.55 0.75
87 INT155392 Negative_regulation of Negative_regulation of Bcl2 3 0.21 1.64 0.74
88 INT134444 Positive_regulation of Binding of Bcl2 3 0.47 2.67 0.72
89 INT14040 Binding of Bak1 2 0.30 0.55 0.72
90 INT14041 Regulation of Binding of Bak1 1 0.23 0 0.68
91 INT204290 Positive_regulation of Bak1 3 0.22 5.19 0.66
92 INT195017 Negative_regulation of Positive_regulation of Aifm1 3 0.24 1.48 0.63
93 INT70025 Positive_regulation of Positive_regulation of BCL2 3 0.27 0.96 0.58
94 INT178128 Negative_regulation of Phosphorylation of BCL2 7 0.27 3.94 0.56
95 INT285007 Regulation of Bak1 1 0.20 3.46 0.56
96 INT155090 Regulation of Positive_regulation of BCL2 3 0.26 1.78 0.54
97 INT176242 Binding of Bax 10 0.42 10.18 0.52
98 INT107187 Gene_expression of Atp2a1 1 0.43 0 0.52
99 INT144696 Regulation of Transcription of Bcl2 5 0.44 2.96 0.51
100 INT135541 Negative_regulation of Bak1 6 0.30 4.52 0.49
101 INT134445 Positive_regulation of Positive_regulation of Bcl2 3 0.47 2.43 0.49
102 INT102108 Protein_catabolism of Bax 8 0.64 5.69 0.48
103 INT221676 Protein_catabolism of Bcl2 4 0.24 2.77 0.48
104 INT134446 Positive_regulation of Binding of Bax 1 0.49 0.72 0.48
105 INT204052 Transcription of Bcl2 5 0.51 3.25 0.45
106 INT140295 Protein_catabolism of BCL2 4 0.64 5.7 0.44
107 INT220424 Positive_regulation of Negative_regulation of Bcl2 2 0.14 1.81 0.44
108 INT152059 Regulation of Transcription of Bax 1 0.26 0.07 0.42
109 INT150946 Negative_regulation of Positive_regulation of Bak1 2 0.29 3.02 0.4
110 INT135802 Positive_regulation of Negative_regulation of Bax 2 0.41 0.57 0.4
111 INT137640 Negative_regulation of Localization of Aifm1 2 0.58 0.39 0.39
112 INT155724 Negative_regulation of Transcription of Bcl2 6 0.53 2.35 0.37
113 INT204069 Negative_regulation of Positive_regulation of Bax 5 0.31 3.08 0.34
114 INT169538 Negative_regulation of Localization of Bax 3 0.49 1.41 0.34
115 INT184482 Positive_regulation of Positive_regulation of Bax 5 0.41 4.7 0.33
116 INT172216 Binding of Bak1 5 0.25 8.48 0.33
117 INT221191 Negative_regulation of Localization of Bax 4 0.38 2.85 0.33
118 INT93093 Regulation of Gene_expression of Bak1 3 0.30 2.09 0.32
119 INT164827 Negative_regulation of Atp2a1 1 0.43 0.15 0.32
120 INT122950 Binding of BAK1 16 0.41 12.85 0.31
121 INT140379 Positive_regulation of Gene_expression of Bak1 4 0.27 2.27 0.31
122 INT229853 Gene_expression of Bak1 2 0.25 2.04 0.29
123 INT178114 Positive_regulation of Phosphorylation of BCL2 11 0.49 4.44 0.28
124 INT102111 Positive_regulation of Protein_catabolism of Bax 2 0.45 1.14 0.27
125 INT239955 Gene_expression of Atp2a1 7 0.29 0.78 0.26
126 INT150947 Positive_regulation of Positive_regulation of Bak1 1 0.05 0.6 0.25
127 INT292743 Negative_regulation of Binding of Bcl2 1 0.05 1.97 0.24
128 INT135543 Negative_regulation of Positive_regulation of Bax 5 0.30 6.4 0.23
129 INT285003 Positive_regulation of Regulation of Bcl2 1 0.46 0.68 0.23
130 INT108563 Negative_regulation of Regulation of Bcl2 1 0.32 0.74 0.22
131 INT187555 Transcription of BAK1 3 0.19 2.6 0.21
132 INT187556 Regulation of Transcription of BAK1 1 0.02 1.22 0.21
133 INT195004 Negative_regulation of Gene_expression of Aifm1 1 0.24 1.22 0.21
134 INT282088 Localization of Bak1 6 0.54 3.78 0.19
135 INT220426 Regulation of Negative_regulation of Bcl2 1 0.05 0.81 0.18
136 INT300463 Regulation of Regulation of Bax 1 0.29 1.33 0.18
137 INT198036 Negative_regulation of BAK1 5 0.27 5.98 0.17
138 INT238507 Regulation of Regulation of BCL2 3 0.44 5.14 0.16
139 INT101109 Negative_regulation of Localization of Bcl2 1 0.03 0.62 0.16
140 INT271019 Negative_regulation of Atp2a1 1 0.19 1.75 0.16
141 INT164832 Positive_regulation of Atp2a1 1 0.30 0.07 0.16
142 INT164828 Negative_regulation of Negative_regulation of Atp2a1 1 0.31 0.07 0.16
143 INT229235 Regulation of Localization of BCL2 2 0.29 3.7 0.15
144 INT102109 Protein_catabolism of Bcl2 1 0.65 0.55 0.15
145 INT110957 Positive_regulation of Positive_regulation of Bcl2 3 0.35 2.3 0.13
146 INT320315 Protein_catabolism of BAK1 3 0.76 3.13 0.13
147 INT285005 Negative_regulation of Bak1 1 0.14 0.16 0.13
148 INT185872 Localization of BAK1 6 0.74 11.28 0.12
149 INT265485 Positive_regulation of Localization of BAK1 4 0.50 5.17 0.12
150 INT185907 Positive_regulation of Binding of BAK1 2 0.60 1.59 0.12
151 INT179038 Positive_regulation of Regulation of Bcl2 1 0.39 3.49 0.12
152 INT238490 Regulation of Regulation of BAK1 1 0.19 2.56 0.12
153 INT220472 Gene_expression of BAG6 1 0.11 13.93 0.12
154 INT336888 Negative_regulation of Transcription of Bax 1 0.07 0.68 0.11
155 INT322449 Regulation of Atp2a1 1 0.13 1.22 0.1
156 INT304137 Regulation of Localization of Bax 2 0.24 1.7 0.09
157 INT327140 Regulation of Localization of BAK1 1 0.45 0.71 0.07
158 INT285012 Positive_regulation of Positive_regulation of Bak1 1 0.16 0.77 0.07
159 INT195011 Positive_regulation of Positive_regulation of Aifm1 1 0.23 0.77 0.07
160 INT322649 Positive_regulation of Localization of Bak1 1 0.47 1.04 0.07
161 INT307466 Positive_regulation of Phosphorylation of Bax 1 0.15 0.76 0.07
162 INT285008 Negative_regulation of Regulation of Bak1 1 0.14 0.87 0.07
163 INT333214 Regulation of Bak1 1 0.18 1.1 0.06
164 INT268304 Negative_regulation of Gene_expression of Bak1 3 0.28 1.95 0.05
165 INT268622 Regulation of Negative_regulation of Bax 1 0.12 0.81 0.05
166 INT302229 Negative_regulation of Negative_regulation of BCL2 3 0.21 2.69 0.04
167 INT309494 Negative_regulation of Binding of Bax 2 0.38 1.31 0.04
168 INT340387 Regulation of Positive_regulation of Bax 1 0.27 0.61 0.04
169 INT322455 Negative_regulation of Gene_expression of Atp2a1 1 0.12 0.54 0.04
170 INT340390 Regulation of Binding of Bax 1 0.54 0.59 0.04
171 INT123525 Phosphorylation of Bax 3 0.41 1.18 0.03
172 INT258045 Positive_regulation of Regulation of BCL2 2 0.36 1.78 0.03
173 INT221673 Negative_regulation of Protein_catabolism of Bcl2 1 0.11 0.15 0.03
174 INT176247 Positive_regulation of Phosphorylation of Bax 1 0.12 0.42 0.03
175 INT271023 Negative_regulation of Negative_regulation of Atp2a1 1 0.19 0.06 0.03
176 INT123521 Phosphorylation of Bcl2 8 0.81 5 0
177 INT254700 Regulation of Gene_expression of BAK1 4 0.39 1.36 0
178 INT310419 Negative_regulation of Localization of BCL2 3 0.41 2.51 0
179 INT185909 Regulation of Phosphorylation of BCL2 3 0.24 1.63 0
180 INT155391 Positive_regulation of Negative_regulation of Bcl2 2 0.22 0.92 0
181 INT185887 Regulation of Binding of BCL2 2 0.24 2.22 0
182 INT183619 Negative_regulation of Regulation of BCL2 2 0.33 1.01 0
183 INT191056 Negative_regulation of Binding of Bcl2 2 0.37 0.48 0
184 INT153083 Positive_regulation of Negative_regulation of BCL2 2 0.32 2.9 0
185 INT322446 Negative_regulation of Transcription of Atp2a1 1 0.12 0.21 0
186 INT330041 Positive_regulation of Regulation of Bax 1 0.29 1.63 0
187 INT333213 Regulation of Transcription of Bax 1 0.11 0.14 0
188 INT333223 Phosphorylation of Bak1 1 0.32 0.69 0
189 INT333207 Regulation of Transcription of Bak1 1 0.18 0.15 0
190 INT333212 Transcription of Bak1 1 0.27 0.15 0
191 INT204053 Negative_regulation of Transcription of Bcl2 1 0.04 0.86 0
192 INT330962 Negative_regulation of Transcription of BCL2 1 0.10 1.21 0
193 INT220466 Regulation of BAG6 1 0.04 1.58 0
194 INT195010 Binding of Aifm1 1 0.21 0.23 0
195 INT322460 Positive_regulation of Atp2a1 1 0.10 0.42 0
196 INT322640 Positive_regulation of Binding of Bax 1 0.12 0.88 0
197 INT282976 Positive_regulation of Binding of Bcl2 1 0.29 0.76 0
198 INT191048 Positive_regulation of Phosphorylation of Bcl2 1 0.69 0.44 0
199 INT220467 Positive_regulation of Gene_expression of BAG6 1 0.07 1.47 0
200 INT53281 Regulation of Atp2a1 1 0.11 0 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox