GO:0070062

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Name extracellular vesicular exosome
Categary Component
Go Slim No
Go Link GO:0070062
Unique Molecular Interactions 98
Total Molecular Interactions 122
Total Single Events 1135
Pain Genes Associated 13

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for extracellular vesicular exosome. They are ordered first by their pain relevance and then by number of times they were reported for extracellular vesicular exosome. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT342165 Binding of Aqp1 and Nav1 1 0.25 0.57 1.25
2 INT255260 Binding of Cd47 and Tsp1 1 0.20 1.42 0.67
3 INT309157 Aqp1 Positive_regulation of Bdnf 1 0.00 0.74 0.42
4 INT288700 Binding of Cp and Tfrc 1 0.40 0 0.39
5 INT93694 Binding of Hspa8 and Ptgs1 1 0.30 0.79 0.36
6 INT141871 Binding of Nos3 and Slc2a4 1 0.25 0.51 0.28
7 INT141870 Binding of Slc2a4 and Cav1 1 0.36 0.38 0.28
8 INT120975 Ins1 Positive_regulation of Gene_expression of Slc2a4 1 0.19 0.75 0.27
9 INT252356 Binding of THBS1 and Cd47 1 0.00 0.44 0.24
10 INT269066 Binding of Hspa8 and Il6 1 0.00 0.74 0.23
11 INT255261 Tsp1 Positive_regulation of Binding of Cd47 1 0.27 0.5 0.23
12 INT244015 Binding of Cd47 and Magt1 1 0.01 0.08 0.21
13 INT151424 Tfrc Negative_regulation of Positive_regulation of Tnni3 1 0.21 0.98 0.2
14 INT342163 Nkx2-1 Regulation of Gene_expression of Aqp1 1 0.06 0.51 0.2
15 INT252330 Binding of Cd36 and Cd47 2 0.10 0.72 0.19
16 INT224086 Binding of Agtr1a and Hspa8 1 0.00 0.1 0.19
17 INT55300 Slc2a1 Regulation of Gene_expression of Slc2a4 1 0.41 0.41 0.19
18 INT55296 Slc2a4 Regulation of Ins1 1 0.17 0.41 0.19
19 INT55299 Slc2a4 Regulation of Gene_expression of Slc2a1 1 0.41 0.41 0.19
20 INT291788 ALDOA Positive_regulation of Gnat3 2 0.02 0.52 0.18
21 INT93693 Positive_regulation of Binding of Hspa8 and Ptgs1 1 0.31 0.38 0.17
22 INT330433 ALDOA Positive_regulation of esterase 1 0.00 0.46 0.17
23 INT165751 Hspa8 Positive_regulation of Protein_catabolism of Rgs9 1 0.50 0.17 0.17
24 INT197499 Binding of Apoe and Tfrc 1 0.14 1.54 0.17
25 INT330430 ALDOA Positive_regulation of Pcyt2 1 0.01 0.47 0.17
26 INT224126 Binding of Hspa8 and Agtr1a 1 0.00 0.09 0.17
27 INT85333 Aqp1 Positive_regulation of Negative_regulation of Tgfb1 1 0.25 0.67 0.15
28 INT279031 Binding of Sirpa and Cd47 1 0.09 0.77 0.15
29 INT327829 Aqp1 Regulation of Binding of Csf2 1 0.11 1 0.14
30 INT126922 Ins1 Positive_regulation of Localization of Slc2a4 1 0.23 0.75 0.11
31 INT151423 Tfrc Positive_regulation of Gene_expression of Nos2 1 0.24 0.49 0.1
32 INT229333 Binding of Nr1h2 and Positive_regulation of Gene_expression of SLC2A4 1 0.02 0.62 0.07
33 INT55297 Gene_expression of Slc2a4 Positive_regulation of Ins1 1 0.19 0.36 0.06
34 INT291749 ALDOA Regulation of ALDH2 1 0.04 0 0.05
35 INT238314 Pik3cb Negative_regulation of Localization of Slc2a4 1 0.06 0.25 0.05
36 INT284448 Il11 Positive_regulation of Hspa8 1 0.04 0.42 0.05
37 INT291750 ALDOA Positive_regulation of ALDH2 1 0.08 0 0.05
38 INT329219 Ins1 Positive_regulation of Gene_expression of Slc2a4 1 0.04 0.93 0.05
39 INT291757 ALDOA Negative_regulation of Positive_regulation of SGCB 1 0.01 0 0.04
40 INT291751 ALDOA Positive_regulation of PON1 1 0.01 0 0.04
41 INT291792 Regulation of Binding of ALDOA and Gnat3 1 0.02 0 0.04
42 INT291789 Binding of ALDOA and Gnat3 1 0.01 0 0.04
43 INT352519 INS Positive_regulation of Localization of Slc2a4 1 0.07 0.97 0.03
44 INT348225 Glp1r Regulation of Localization of Slc2a4 1 0.36 0.66 0.03
45 INT348223 Glp1r Regulation of Positive_regulation of Slc2a4 1 0.26 0.66 0.03
46 INT291756 ALDH2 Positive_regulation of ALDOA 1 0.06 0 0.03
47 INT348224 Glp1r Regulation of Slc2a4 1 0.26 0.66 0.03
48 INT225592 Binding of Tfrc and Pprc1 1 0.00 0 0
49 INT291783 ALDOA Regulation of Gnat3 1 0.01 0 0
50 INT330432 ALDOA Positive_regulation of Binding of Aldh2 1 0.03 0.43 0
51 INT291753 ALDOA Positive_regulation of ALDH1A1 1 0.00 0 0
52 INT255752 hs Positive_regulation of Phosphorylation of Slc2a4 1 0.08 1.32 0
53 INT225505 Ncoa6 Positive_regulation of Positive_regulation of Tfrc 1 0.10 0 0
54 INT225591 Asc2 Positive_regulation of Positive_regulation of Tfrc 1 0.03 0 0
55 INT291754 ALDOA Negative_regulation of ALDH2 1 0.07 0 0
56 INT296959 NRIP1 Regulation of SLC2A4 1 0.22 0.54 0
57 INT225561 Binding of Tfrc and Ncoa6 1 0.07 0 0
58 INT252791 Binding of IREB2 and TFRC 1 0.02 1.82 0
59 INT252807 Binding of ACO1 and TFRC 1 0.01 1.83 0
60 INT225523 Rbm39 Positive_regulation of Positive_regulation of Tfrc 1 0.03 0 0
61 INT262498 Binding of Aqp1 and Cav1 1 0.03 0.56 0
62 INT225571 Binding of Ncoa1 and Tfrc 1 0.01 0 0
63 INT225574 Rbm39 Positive_regulation of Tfrc 1 0.03 0 0
64 INT330434 ALDOA Positive_regulation of Aldh2 1 0.03 0.38 0
65 INT330431 Binding of ALDOA and Aldh2 1 0.03 0 0
66 INT96974 Binding of Atp7b and Tfrc 1 0.06 0.06 0
67 INT98626 Aqp1 Positive_regulation of Aqp4 1 0.52 0 0
68 INT291755 ALDOA Negative_regulation of PON1 1 0.00 0 0
69 INT255749 Ptch1 Positive_regulation of Phosphorylation of Slc2a4 1 0.15 1.32 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for extracellular vesicular exosome. They are ordered first by their pain relevance and then by number of times they were reported in extracellular vesicular exosome. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT104567 Gene_expression of Aqp1 47 0.78 44.84 28.68
2 INT48131 Gene_expression of Slc2a4 32 0.78 14.64 10.16
3 INT15805 Gene_expression of TFRC 35 0.75 17.44 8.52
4 INT99430 Positive_regulation of Gene_expression of Slc2a4 18 0.66 10.45 7.79
5 INT156134 Regulation of Gene_expression of Aqp1 5 0.59 7.2 5.3
6 INT85328 Negative_regulation of Aqp1 5 0.54 6.02 4.94
7 INT129746 Positive_regulation of Gene_expression of Tfrc 4 0.18 2.15 3.74
8 INT85326 Positive_regulation of Aqp1 7 0.65 5.9 3.71
9 INT104570 Localization of Aqp1 8 0.77 5.83 3.51
10 INT15801 Positive_regulation of TFRC 11 0.33 6.35 3.3
11 INT68846 Gene_expression of Tfrc 22 0.32 10.1 3.06
12 INT117121 Gene_expression of Hspa8 7 0.65 4.92 2.94
13 INT115250 Positive_regulation of Slc2a4 16 0.67 8.13 2.64
14 INT51753 Negative_regulation of Tfrc 7 0.41 3.47 2.62
15 INT48130 Transcription of Slc2a4 9 0.69 5.58 2.46
16 INT21726 Gene_expression of Tfrc 10 0.74 7.38 2.36
17 INT141721 Binding of Aqp1 5 0.37 1.77 2.15
18 INT203308 Regulation of Aqp1 4 0.48 2.59 2.13
19 INT82543 Negative_regulation of Gene_expression of TFRC 4 0.57 1.27 2.03
20 INT83332 Regulation of Gene_expression of TFRC 5 0.22 3.03 1.99
21 INT115256 Localization of Slc2a4 13 0.77 8.06 1.72
22 INT48126 Negative_regulation of Gene_expression of Slc2a4 5 0.59 1.79 1.63
23 INT48128 Regulation of Gene_expression of Slc2a4 5 0.62 1.25 1.59
24 INT230805 Localization of Slc2a4 23 0.46 11 1.48
25 INT59795 Regulation of Tfrc 5 0.43 4.43 1.48
26 INT15798 Positive_regulation of Gene_expression of TFRC 9 0.46 4.99 1.42
27 INT117122 Positive_regulation of Gene_expression of Hspa8 1 0.40 0.45 1.4
28 INT73180 Positive_regulation of Hspa8 7 0.37 3.41 1.37
29 INT327824 Positive_regulation of Gene_expression of Aqp1 4 0.67 5.4 1.37
30 INT73553 Gene_expression of Aqp1 23 0.67 4.65 1.34
31 INT279019 Gene_expression of Cd47 3 0.56 1.43 1.31
32 INT48129 Negative_regulation of Slc2a4 7 0.59 3.19 1.21
33 INT6996 Positive_regulation of Tfrc 6 0.70 2.22 1.2
34 INT55294 Gene_expression of Slc2a4 17 0.70 6.84 1.11
35 INT82540 Negative_regulation of TFRC 3 0.41 0.77 1.07
36 INT184479 Regulation of Tfrc 3 0.09 3.97 1.01
37 INT252313 Positive_regulation of Cd47 4 0.22 3.95 0.87
38 INT141865 Positive_regulation of Transcription of Slc2a4 3 0.45 2.78 0.87
39 INT21727 Positive_regulation of Gene_expression of Tfrc 3 0.19 1.68 0.82
40 INT115249 Binding of Slc2a4 7 0.36 2.63 0.8
41 INT197722 Regulation of TFRC 4 0.14 1.2 0.72
42 INT230808 Positive_regulation of Localization of Slc2a4 12 0.40 5.42 0.7
43 INT48133 Regulation of Slc2a4 2 0.45 0.23 0.6
44 INT55293 Positive_regulation of Gene_expression of Slc2a4 7 0.63 4.18 0.51
45 INT243960 Binding of Cd47 2 0.18 1.06 0.51
46 INT48132 Negative_regulation of Transcription of Slc2a4 1 0.43 0 0.48
47 INT300578 Negative_regulation of Cd47 1 0.24 0.17 0.44
48 INT300586 Negative_regulation of Gene_expression of Cd47 1 0.33 0.25 0.43
49 INT211918 Binding of Tfrc 9 0.47 0.94 0.38
50 INT126919 Regulation of Localization of Slc2a4 3 0.40 2.24 0.37
51 INT203374 Positive_regulation of Regulation of Aqp1 2 0.36 0.91 0.37
52 INT350630 Negative_regulation of Gene_expression of Cd47 1 0.20 0.8 0.37
53 INT350627 Gene_expression of Cd47 1 0.28 0.79 0.36
54 INT253118 Negative_regulation of Localization of Slc2a4 3 0.25 2.47 0.33
55 INT126920 Phosphorylation of Slc2a4 3 0.73 1.98 0.31
56 INT293551 Regulation of Positive_regulation of Aqp1 1 0.13 0 0.31
57 INT300582 Regulation of Gene_expression of Cd47 1 0.25 0.13 0.28
58 INT62808 Positive_regulation of SLC2A4 7 0.50 3.3 0.24
59 INT62810 Localization of SLC2A4 5 0.81 0.77 0.22
60 INT126921 Positive_regulation of Phosphorylation of Slc2a4 2 0.41 1.26 0.21
61 INT238311 Negative_regulation of Gene_expression of Tfrc 2 0.16 0.48 0.21
62 INT229317 Gene_expression of SLC2A4 10 0.69 6.88 0.2
63 INT104568 Negative_regulation of Localization of Aqp1 1 0.36 2.47 0.2
64 INT231256 Regulation of Slc2a4 3 0.21 0.76 0.18
65 INT118595 Binding of Tfrc 3 0.25 1.24 0.18
66 INT215814 Negative_regulation of Gene_expression of Aqp1 2 0.31 0.25 0.17
67 INT184483 Regulation of Regulation of Tfrc 1 0.01 1.19 0.17
68 INT98625 Regulation of Aqp1 1 0.27 0.1 0.17
69 INT262067 Localization of Tfrc 2 0.68 0.69 0.16
70 INT314810 Localization of Hspa8 1 0.17 0.1 0.15
71 INT277389 Positive_regulation of Gene_expression of SLC2A4 4 0.61 2.87 0.14
72 INT62809 Positive_regulation of Localization of SLC2A4 3 0.70 0.8 0.14
73 INT125740 Protein_catabolism of Tfrc 1 0.02 0 0.13
74 INT115251 Positive_regulation of Localization of Slc2a4 2 0.66 0.9 0.11
75 INT342655 Regulation of Negative_regulation of Tfrc 1 0.10 0 0.11
76 INT229102 Regulation of Phosphorylation of Slc2a4 1 0.00 0.53 0.11
77 INT215820 Negative_regulation of Aqp1 3 0.23 0.83 0.1
78 INT236581 Regulation of Gene_expression of Slc2a4 3 0.36 0.5 0.09
79 INT243806 Negative_regulation of Tfrc 2 0.12 0.43 0.08
80 INT327827 Negative_regulation of Gene_expression of Aqp1 1 0.45 0.8 0.08
81 INT342658 Positive_regulation of Negative_regulation of Tfrc 1 0.12 1.02 0.08
82 INT352512 Regulation of Localization of Slc2a4 1 0.06 0.66 0.08
83 INT262510 Regulation of Gene_expression of Aqp1 1 0.33 1.18 0.07
84 INT258085 Regulation of Localization of SLC2A4 1 0.22 0.75 0.06
85 INT238308 Negative_regulation of Localization of Slc2a4 1 0.12 0.25 0.05
86 INT291770 Gene_expression of ALDOA 6 0.10 1.49 0.04
87 INT149171 Localization of Tfrc 3 0.71 0 0.04
88 INT291767 Positive_regulation of Gene_expression of ALDOA 2 0.07 1.5 0.04
89 INT340886 Binding of Hspa8 1 0.34 0.23 0.04
90 INT314807 Positive_regulation of Hspa8 1 0.09 0.71 0.04
91 INT256851 Regulation of Hspa8 4 0.19 3.71 0.03
92 INT228893 Binding of TFRC 4 0.16 2.81 0.03
93 INT134689 Positive_regulation of ALDOA 3 0.26 0.07 0.03
94 INT253101 Binding of Slc2a4 1 0.21 0 0.03
95 INT342656 Transcription of Tfrc 1 0.17 0 0.03
96 INT291766 Negative_regulation of ALDOA 1 0.05 0 0.03
97 INT340902 Localization of Hspa8 1 0.64 0.14 0.03
98 INT199653 Positive_regulation of Tfrc 2 0.13 1.57 0
99 INT262504 Positive_regulation of Aqp1 1 0.25 0.43 0
100 INT348742 Gene_expression of Hspa8 1 0.38 0 0
101 INT296979 Regulation of Gene_expression of SLC2A4 1 0.19 0.56 0
102 INT314808 Binding of Hspa8 1 0.11 0.3 0
103 INT296970 Positive_regulation of Transcription of SLC2A4 1 0.32 0.99 0
104 INT262513 Negative_regulation of Binding of Aqp1 1 0.23 0.64 0
105 INT268312 Negative_regulation of Negative_regulation of Slc2a4 1 0.26 0.31 0
106 INT317361 Negative_regulation of Gene_expression of Slc2a4 1 0.40 0.15 0
107 INT277382 Negative_regulation of SLC2A4 1 0.38 0.48 0
108 INT296971 Binding of SLC2A4 1 0.26 1.13 0
109 INT262514 Binding of Aqp1 1 0.20 0.64 0
110 INT228891 Positive_regulation of Binding of TFRC 1 0.16 0.63 0
111 INT336105 Positive_regulation of Slc2a4 1 0.39 0.63 0
112 INT315570 Negative_regulation of Positive_regulation of TFRC 1 0.19 0.08 0
113 INT268302 Negative_regulation of Slc2a4 1 0.26 0.31 0
114 INT330421 Binding of ALDOA 1 0.02 0 0
115 INT299193 Transcription of Aqp1 1 0.56 0.62 0
116 INT262511 Positive_regulation of Gene_expression of Aqp1 1 0.37 1.78 0
117 INT296961 Positive_regulation of Binding of SLC2A4 1 0.35 1.14 0
118 INT314809 Negative_regulation of Binding of Hspa8 1 0.13 0.24 0
119 INT348210 Negative_regulation of Binding of Slc2a4 1 0.25 0.5 0
120 INT342654 Regulation of Transcription of Tfrc 1 0.11 0 0
121 INT342657 Regulation of Gene_expression of Tfrc 1 0.07 0.29 0
122 INT291775 Localization of ALDOA 1 0.11 0 0
123 INT296983 Transcription of SLC2A4 1 0.37 1.56 0
124 INT262512 Localization of Aqp1 1 0.40 0.7 0
125 INT255722 Phosphorylation of Slc2a4 1 0.46 1.3 0
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