GO:0070098

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Name chemokine-mediated signaling pathway
Categary Process
Go Slim No
Go Link GO:0070098
Unique Molecular Interactions 301
Total Molecular Interactions 465
Total Single Events 3914
Pain Genes Associated 17

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for chemokine-mediated signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for chemokine-mediated signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52
2 INT189488 Binding of Ccr1 and Ccl5 8 0.40 9.26 3.27
3 INT166134 Binding of Cxcl12 and Cxcr4 3 0.49 5.69 3.17
4 INT149492 PNOC Negative_regulation of Gene_expression of CCL2 1 0.15 0.68 3.17
5 INT182635 Binding of CCR5 and CCL5 2 0.09 4.19 3
6 INT318996 Binding of CCR3 and CCL5 1 0.07 3.39 2.9
7 INT319003 Binding of CCR1 and CCL5 1 0.08 3.38 2.89
8 INT149494 PNOC Negative_regulation of Gene_expression of CCL5 1 0.19 0.52 2.46
9 INT124121 IL6 Positive_regulation of CCL2 1 0.26 1.84 2.25
10 INT124120 IL6 Regulation of CCL2 1 0.15 1.8 2.22
11 INT128997 Cxcl1 Positive_regulation of Localization of Ccl2 1 0.72 1.54 2.16
12 INT128996 Ccl2 Positive_regulation of Localization of Calca 1 0.68 1.43 2
13 INT161224 Ccl2 Positive_regulation of Ccr2 1 0.52 2.09 1.88
14 INT222185 Binding of Ccr1 and Ccl3 4 0.23 2.7 1.47
15 INT222213 TFAM Positive_regulation of Gene_expression of Ccr1 1 0.02 3.96 1.4
16 INT181436 Binding of Ccl2 and Eae1 1 0.05 5.14 1.27
17 INT149844 Negative_regulation of Cxcl12 Negative_regulation of C19orf10 1 0.16 0.45 1.26
18 INT254210 Binding of Cxcr2 and Ccl2 1 0.08 2.39 1.25
19 INT149845 Cxcl12 Negative_regulation of C19orf10 1 0.16 0.45 1.24
20 INT253999 Binding of Cxcl12 and Mif 1 0.41 2.26 1.22
21 INT200455 OPRK1 Positive_regulation of Gene_expression of CCL2 1 0.19 0.07 1.21
22 INT260810 Binding of CXCL10 and CCL2 1 0.10 1.37 1.12
23 INT105109 Cxcl12 Positive_regulation of JUN 1 0.01 1.07 1.05
24 INT181434 Binding of Ccr2 and Ccl2 1 0.27 6.06 1.04
25 INT167173 Binding of Ccl2 and Ccr2 2 0.30 1.15 0.98
26 INT311102 IL8 Positive_regulation of CXCR7 1 0.00 1.74 0.98
27 INT135585 CSF2 Regulation of CCL2 1 0.13 2.51 0.95
28 INT182208 Binding of CXCR2 and CXCL12 1 0.29 1.26 0.95
29 INT182198 Binding of CXCR5 and CXCL12 1 0.33 1.25 0.94
30 INT182209 Binding of CXCL12 and CXCL13 1 0.30 1.24 0.93
31 INT129003 Ccl2 Positive_regulation of ANTXRL 1 0.00 0.68 0.92
32 INT166135 Regulation of Binding of Cxcl12 and Cxcr4 1 0.30 0.9 0.91
33 INT253992 Cxcl12 Positive_regulation of Mif 1 0.46 1.31 0.88
34 INT254004 Cxcl12 Positive_regulation of Cxcr4 1 0.47 1.29 0.86
35 INT253995 Binding of Cxcl12 and Cyp3a23/3a1 1 0.06 1.28 0.85
36 INT146919 Tnf Positive_regulation of Gene_expression of Ccl2 1 0.16 1.44 0.84
37 INT302379 Crp Positive_regulation of Gene_expression of Ccl2 1 0.10 4.58 0.84
38 INT287494 CRP Positive_regulation of Gene_expression of CCL2 2 0.30 2.33 0.83
39 INT149561 Tgfb1 Positive_regulation of Gene_expression of CCL2 1 0.00 0 0.83
40 INT149563 Tgfb1 Positive_regulation of CCL2 1 0.00 0 0.83
41 INT87490 CALCA Positive_regulation of Gene_expression of CCL5 1 0.30 0.14 0.81
42 INT87489 CALCA Positive_regulation of Gene_expression of CCL2 1 0.43 0.14 0.81
43 INT239671 Binding of Ccl2 and Gtf3a 1 0.02 1.34 0.79
44 INT149493 PNOC Negative_regulation of CCL5 1 0.14 0.16 0.77
45 INT149495 PNOC Negative_regulation of CCL2 1 0.11 0.16 0.77
46 INT258644 Binding of CCL2 and CCL5 1 0.36 1.6 0.74
47 INT258643 Positive_regulation of Binding of CCL2 and CCL5 1 0.49 1.61 0.74
48 INT209035 Il2 Positive_regulation of Ccr1 1 0.00 0.38 0.73
49 INT209038 Il4 Positive_regulation of Ccr1 1 0.01 0.38 0.73
50 INT209065 Il3 Positive_regulation of Ccr1 1 0.00 0.38 0.73
51 INT209031 Il12b Positive_regulation of Ccr1 1 0.02 0.37 0.72
52 INT209041 Il10 Positive_regulation of Ccr1 1 0.01 0.37 0.72
53 INT209060 Il6 Positive_regulation of Ccr1 1 0.01 0.38 0.72
54 INT120017 CCL2 Positive_regulation of CCL3 1 0.01 0.99 0.7
55 INT120020 VEGFA Positive_regulation of CCL2 1 0.00 1 0.7
56 INT120035 CCL2 Positive_regulation of Prap1 1 0.00 0.99 0.7
57 INT130717 Binding of OPRM1 and Positive_regulation of Localization of CCL2 1 0.00 0.72 0.68
58 INT222211 TFAM Positive_regulation of Ccr1 1 0.02 1.89 0.68
59 INT297307 Negative_regulation of Binding of Ccr1 and Ccl3 1 0.27 0.73 0.67
60 INT297313 Negative_regulation of Binding of Ccr1 and Ccl5 1 0.28 0.74 0.67
61 INT254352 Binding of CXCR4 and Positive_regulation of Gene_expression of CXCL12 1 0.14 1.8 0.66
62 INT116441 IL1B Positive_regulation of Gene_expression of CCL2 2 0.04 0.62 0.65
63 INT153750 Binding of CCL2 and Crp 1 0.02 1.8 0.65
64 INT153751 Regulation of Binding of CCL2 and Crp 1 0.03 1.8 0.65
65 INT281130 Ccl2 Regulation of Gene_expression of Ccr2 1 0.04 1.09 0.64
66 INT264329 Binding of IL-17 and Positive_regulation of Localization of Ccl2 1 0.13 1.65 0.64
67 INT281134 Ccl2 Positive_regulation of Gene_expression of Ccr2 1 0.08 1.09 0.64
68 INT281122 Ccl2 Regulation of Ccr2 1 0.04 1.09 0.63
69 INT174860 VEGFA Positive_regulation of Localization of CCL2 1 0.21 1.68 0.63
70 INT252772 ELANE Regulation of Gene_expression of CCL2 1 0.05 2.16 0.62
71 INT252826 ROS1 Regulation of Gene_expression of CCL2 1 0.20 2.17 0.62
72 INT295724 CXCL12 Positive_regulation of MMP9 1 0.02 0.32 0.6
73 INT316831 CCL5 Positive_regulation of Gene_expression of MMP2 1 0.02 0.51 0.59
74 INT176470 TNF Positive_regulation of Gene_expression of CCL2 1 0.15 0.62 0.58
75 INT147201 Binding of CCL2 and Hsp70-2os 1 0.00 0.76 0.57
76 INT97635 ABCF1 Positive_regulation of Localization of CCR1 1 0.05 0.51 0.55
77 INT222252 Positive_regulation of Binding of Ccr2 and Fig4 1 0.16 0.67 0.55
78 INT222246 Binding of Ccr2 and Tcf21 1 0.29 0.67 0.55
79 INT253998 Cyp3a23/3a1 Positive_regulation of Binding of Cxcl12 1 0.10 0.65 0.55
80 INT253990 Cyp3a23/3a1 Positive_regulation of Cxcl12 1 0.09 0.65 0.55
81 INT222249 Positive_regulation of Binding of Ccr2 and Tcf21 1 0.39 0.67 0.55
82 INT222245 Binding of Ccr2 and Fig4 1 0.12 0.67 0.55
83 INT210934 Gene_expression of Tlr4 Negative_regulation of Ccl2 1 0.47 0.69 0.54
84 INT105110 Cxcl12 Positive_regulation of NFKB1 1 0.06 0.54 0.53
85 INT105108 Negative_regulation of Cxcl12 Positive_regulation of NFKB1 1 0.05 0.54 0.53
86 INT295708 Binding of EGF and CCL2 1 0.01 0.79 0.49
87 INT171278 TNFSF12 Positive_regulation of CCL5 1 0.02 0.93 0.48
88 INT217040 Negative_regulation of IRF6 Positive_regulation of CCL2 1 0.00 1.24 0.47
89 INT217039 IRF6 Positive_regulation of CCL2 1 0.00 1.24 0.47
90 INT146506 Regulation of Gfap Regulation of Gene_expression of Ccl2 1 0.08 0.7 0.46
91 INT281126 Binding of Ccr2 and Cxcr4 1 0.30 0.32 0.44
92 INT112800 CASP1 Positive_regulation of Gene_expression of CCL2 1 0.04 0.48 0.43
93 INT184543 Agt Positive_regulation of Ccl2 1 0.16 3.18 0.43
94 INT254636 Bdkrb2 Regulation of Gene_expression of Ccl2 1 0.15 1.15 0.43
95 INT345288 AGT Positive_regulation of Localization of CCL2 1 0.01 1.5 0.43
96 INT345291 AGT Positive_regulation of CCL2 1 0.01 1.39 0.43
97 INT332248 Ccl2 Positive_regulation of Ctgf 1 0.04 1.13 0.42
98 INT181448 Eae1 Positive_regulation of Gene_expression of Ccr2 1 0.04 4.98 0.42
99 INT316830 TNF Regulation of CCL5 1 0.02 1.02 0.39
100 INT181081 Binding of Ccr1 and Darc 1 0.01 1.08 0.39
101 INT181441 Csf2 Positive_regulation of Cxcl12 1 0.02 1.69 0.39
102 INT163909 CCL2 Positive_regulation of Positive_regulation of Ccr2 1 0.05 0.19 0.36
103 INT181438 Il4 Regulation of Gene_expression of Ccl2 1 0.38 0.74 0.35
104 INT163906 CCL2 Positive_regulation of CCR2 1 0.18 0.2 0.35
105 INT163908 CCL2 Positive_regulation of Ccr2 1 0.05 0.2 0.35
106 INT181453 Gene_expression of Ccl2 Positive_regulation of Gene_expression of Il12rb1 1 0.06 1.87 0.34
107 INT236955 Binding of Cxcr5 and Cxcl13 1 0.28 2.26 0.34
108 INT134888 Negative_regulation of TNFRSF11A Negative_regulation of Gene_expression of CCL2 1 0.24 0.38 0.33
109 INT190290 Binding of CXCL12 and VIPR1 1 0.06 0 0.33
110 INT181435 Binding of Ccr2 and Hand2 1 0.17 1.81 0.32
111 INT280926 Hoxa3 Positive_regulation of Gene_expression of Ccl2 1 0.53 2.61 0.32
112 INT181433 Hand2 Regulation of Gene_expression of Ccl2 1 0.12 0.68 0.32
113 INT322964 Binding of IL8 and Cxcl12 1 0.30 0.2 0.32
114 INT244233 Ccr1 Positive_regulation of Cxcr1 1 0.16 0.08 0.32
115 INT313740 Negative_regulation of NOS1 Positive_regulation of Gene_expression of Ccl2 1 0.02 0.38 0.3
116 INT272925 Ccl2 Positive_regulation of Gene_expression of Col7a1 1 0.00 0.72 0.3
117 INT171257 TNFSF12 Positive_regulation of CCL2 1 0.01 0.3 0.29
118 INT181442 Ccl2 Positive_regulation of Localization of Hand2 1 0.26 0.63 0.29
119 INT306107 Binding of CCL2 and Ccr2 1 0.06 0 0.28
120 INT294709 IRF6 Positive_regulation of Gene_expression of CCL2 1 0.08 0.14 0.28
121 INT333246 Binding of Cxcr4 and Cxcl12 3 0.34 0.99 0.27
122 INT154755 Tnf Positive_regulation of Gene_expression of Ccl2 2 0.23 1.7 0.27
123 INT252806 F2 Positive_regulation of Gene_expression of CCL2 1 0.01 0.8 0.27
124 INT306941 Tnfsf12 Positive_regulation of Gene_expression of CCL2 1 0.03 1.65 0.27
125 INT132363 Lgals1 Positive_regulation of Gene_expression of Ccl2 1 0.26 0.14 0.27
126 INT342458 CSF1 Positive_regulation of Gene_expression of CCL2 1 0.17 0.84 0.27
127 INT103279 PGR Negative_regulation of Gene_expression of CCL5 1 0.32 0.31 0.27
128 INT254635 Positive_regulation of Eae1 Positive_regulation of Gene_expression of Ccl2 1 0.15 1.07 0.27
129 INT353448 BRCA1 Positive_regulation of CCL2 1 0.01 1.37 0.26
130 INT268766 Tlr4 Positive_regulation of Gene_expression of Ccr1 1 0.04 0.4 0.26
131 INT120896 Binding of CCL2 and Il6 1 0.08 1.2 0.26
132 INT237082 Binding of Cxcl9 and Cxcl13 1 0.22 1.51 0.26
133 INT312768 Pon1 Negative_regulation of Gene_expression of Ccl2 1 0.06 1.42 0.26
134 INT266802 Dlst Positive_regulation of CCL5 1 0.00 0.95 0.25
135 INT252815 Binding of CCL5 and TNF 1 0.02 0.75 0.25
136 INT252822 CCL2 Positive_regulation of Positive_regulation of FOS 1 0.04 0.75 0.25
137 INT181449 Ccl7 Regulation of Ccl2 1 0.24 0.73 0.25
138 INT342456 AGT Positive_regulation of Gene_expression of CCL2 1 0.07 0.63 0.25
139 INT252786 CCL2 Regulation of Positive_regulation of FOS 1 0.05 0.75 0.25
140 INT281133 Binding of Ccl2 and Cxcr4 1 0.06 0.63 0.24
141 INT329368 Ccl2 Negative_regulation of Jun 1 0.01 1.87 0.24
142 INT252777 ROS1 Positive_regulation of Gene_expression of CCL2 1 0.31 0.77 0.23
143 INT268768 Mip Regulation of Positive_regulation of Ccr1 1 0.44 0.83 0.23
144 INT80286 IFNG Positive_regulation of Gene_expression of CCL5 1 0.24 0.37 0.23
145 INT80287 IL4 Positive_regulation of Gene_expression of CCL5 1 0.21 0.37 0.23
146 INT112796 IL4I1 Positive_regulation of Gene_expression of CCL2 1 0.07 0 0.23
147 INT112801 IL4I1 Positive_regulation of CCL2 1 0.03 0 0.23
148 INT170993 IL10 Positive_regulation of Gene_expression of CCR1 1 0.12 0.34 0.22
149 INT291352 Positive_regulation of CXCL12 Positive_regulation of ERBB2 1 0.17 0.88 0.22
150 INT112798 CASP1 Positive_regulation of CCL2 1 0.02 0.19 0.21
151 INT196635 CFTR Positive_regulation of Gene_expression of CCL5 1 0.07 0.44 0.21
152 INT253991 Negative_regulation of Binding of Cxcl12 and Cxcr4 1 0.43 0.41 0.21
153 INT295713 PTGER2 Positive_regulation of Regulation of CCL5 1 0.01 0.82 0.21
154 INT158209 Binding of CCR1 and AHSA1 1 0.17 0.3 0.2
155 INT158225 Binding of CCR1 and MAPK1 1 0.18 0.3 0.2
156 INT158222 Positive_regulation of Binding of MAPK1 and CCR2 1 0.26 0.3 0.2
157 INT158207 Positive_regulation of Binding of TNFSF14 and CCR2 1 0.07 0.3 0.2
158 INT158231 TNFSF14 Positive_regulation of CCR1 1 0.07 0.3 0.2
159 INT158224 TNFSF14 Positive_regulation of CCR2 1 0.07 0.3 0.2
160 INT158210 Binding of CCR1 and TNFSF14 1 0.05 0.3 0.2
161 INT158212 Negative_regulation of Binding of CCR1 and AHSA1 1 0.20 0.3 0.2
162 INT158204 Negative_regulation of Binding of MAPK1 and CCR2 1 0.22 0.3 0.2
163 INT158198 Negative_regulation of Binding of AHSA1 and CCR2 1 0.21 0.3 0.2
164 INT158206 Binding of TNFSF14 and CCR2 1 0.05 0.3 0.2
165 INT158200 Positive_regulation of Binding of CCR1 and AHSA1 1 0.23 0.3 0.2
166 INT158216 Negative_regulation of Binding of TNFSF14 and CCR2 1 0.06 0.3 0.2
167 INT158201 Positive_regulation of Binding of CCR1 and TNFSF14 1 0.07 0.3 0.2
168 INT158217 Binding of AHSA1 and CCR2 1 0.18 0.3 0.2
169 INT252814 ELANE Positive_regulation of Positive_regulation of CCL2 1 0.05 0.8 0.2
170 INT158234 Binding of MAPK1 and CCR2 1 0.19 0.3 0.2
171 INT306108 CCL2 Positive_regulation of Positive_regulation of Mapk3 1 0.03 0.15 0.2
172 INT158221 Positive_regulation of Binding of CCR1 and MAPK1 1 0.25 0.3 0.2
173 INT158230 Negative_regulation of Binding of CCR1 and TNFSF14 1 0.06 0.3 0.2
174 INT158235 Positive_regulation of Binding of AHSA1 and CCR2 1 0.24 0.3 0.2
175 INT158219 Negative_regulation of Binding of CCR1 and MAPK1 1 0.21 0.3 0.2
176 INT252782 ROS1 Positive_regulation of Positive_regulation of CCL2 1 0.22 0.8 0.2
177 INT181440 Binding of Ccr2 and Eae1 1 0.03 1.3 0.19
178 INT23585 Binding of KRIT1 and CCR1 1 0.40 0.97 0.19
179 INT170995 Binding of IFNA1 and Positive_regulation of Localization of CCL5 1 0.03 0.34 0.19
180 INT303937 Positive_regulation of Binding of GLI2 and CCL5 1 0.01 0 0.18
181 INT303940 Regulation of Binding of GLI2 and CCL5 1 0.01 0 0.18
182 INT184540 Agt Regulation of Gene_expression of Ccl2 1 0.08 1.66 0.18
183 INT333250 Binding of Cxcr7 and Cxcl12 1 0.19 1.39 0.18
184 INT304964 Binding of AMT and PTK2B 1 0.23 0.78 0.18
185 INT226344 Gene_expression of IL9 Positive_regulation of CCL5 1 0.07 1.03 0.18
186 INT303938 Binding of GLI2 and CCL5 1 0.01 0 0.18
187 INT172250 Binding of APLNR and CCR1 1 0.12 0 0.17
188 INT353361 Positive_regulation of Binding of Cxcr4 and Cxcl12 1 0.46 0 0.17
189 INT329795 IL6 Positive_regulation of Transcription of CCL5 1 0.02 0.59 0.17
190 INT291354 CXCL12 Positive_regulation of EPHB2 1 0.42 2.02 0.16
191 INT116440 LY9 Negative_regulation of Gene_expression of CCL2 1 0.14 0.09 0.16
192 INT303941 CCL2 Positive_regulation of Protein_catabolism of GLI2 1 0.01 0 0.16
193 INT333255 Cxcl12 Regulation of Mcl1 1 0.12 1.12 0.15
194 INT333241 Cxcl12 Regulation of Bcl2l11 1 0.18 1.11 0.15
195 INT353359 Binding of Cxcl12 and Regulation of Nes 1 0.25 0.3 0.15
196 INT353360 Binding of Cxcl12 and Positive_regulation of Gene_expression of Hist1h3f 1 0.03 0.3 0.15
197 INT352417 Ccl2 Positive_regulation of Ccr5 1 0.06 0.26 0.14
198 INT352416 Ccl2 Positive_regulation of Ccr2 1 0.23 0.26 0.14
199 INT268765 Tlr4 Positive_regulation of Positive_regulation of Ccr1 1 0.04 0.27 0.13
200 INT220318 Binding of CPB1 and CCL2 1 0.01 0.46 0.13

Single Events

The table below shows the top 100 pain related interactions that have been reported for chemokine-mediated signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in chemokine-mediated signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02
2 INT82878 Gene_expression of Ccl2 201 0.78 164.95 101.35
3 INT102546 Gene_expression of Ccl2 197 0.78 192.8 67.41
4 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85
5 INT78899 Gene_expression of CCL5 155 0.77 84.02 55.09
6 INT81498 Positive_regulation of Gene_expression of CCL2 107 0.70 53.89 45.22
7 INT82883 Positive_regulation of Ccl2 105 0.69 84.96 42.27
8 INT65698 Localization of CCL2 118 0.81 77.54 32.69
9 INT84170 Positive_regulation of Gene_expression of Ccl2 58 0.69 48.79 32.43
10 INT88046 Gene_expression of Ccr2 38 0.76 33.76 28.07
11 INT82882 Localization of Ccl2 61 0.80 41.96 28
12 INT141612 Gene_expression of Ccr1 92 0.77 72.09 24.14
13 INT78901 Localization of CCL5 67 0.78 40.79 20.59
14 INT102545 Gene_expression of Ccr2 42 0.78 61.43 19.81
15 INT138696 Positive_regulation of Ccl2 57 0.67 59.57 19.58
16 INT66857 Regulation of CCL2 39 0.53 28.55 18.35
17 INT84171 Negative_regulation of Gene_expression of Ccl2 30 0.58 26.37 18.28
18 INT55880 Negative_regulation of Gene_expression of CCL2 49 0.59 22.37 18.09
19 INT55878 Regulation of Gene_expression of CCL2 34 0.62 15.71 17.97
20 INT113602 Positive_regulation of Gene_expression of Ccl2 48 0.70 48.71 17.85
21 INT151434 Positive_regulation of Ccr2 26 0.68 18.34 16.34
22 INT107585 Gene_expression of CCR2 35 0.71 26.44 14.75
23 INT108485 Gene_expression of CXCL12 61 0.75 49.34 13.79
24 INT96850 Negative_regulation of CCL2 42 0.59 24.89 12.55
25 INT4240 Positive_regulation of CCL5 32 0.58 20.55 10.65
26 INT78895 Regulation of CCL5 30 0.46 20.45 10.18
27 INT222233 Gene_expression of Cxcl12 42 0.69 32.64 10.13
28 INT83450 Positive_regulation of Localization of CCL2 28 0.70 22.14 9.83
29 INT106200 Binding of Ccl2 22 0.42 16.7 9.75
30 INT87495 Positive_regulation of Gene_expression of CCL5 26 0.69 13.85 9.46
31 INT135407 Negative_regulation of Ccl2 33 0.57 32.74 9.45
32 INT140224 Localization of Ccl2 32 0.72 26.91 9.39
33 INT138700 Negative_regulation of Gene_expression of Ccl2 27 0.57 24.1 9.08
34 INT161222 Positive_regulation of Ccr2 13 0.55 13.77 8.89
35 INT88047 Positive_regulation of Gene_expression of Ccr2 15 0.60 10.5 8.63
36 INT126478 Gene_expression of Cxcl12 78 0.77 58.69 8.01
37 INT166881 Positive_regulation of Ccr1 31 0.69 18.14 7.9
38 INT102548 Negative_regulation of Ccr2 14 0.59 19.84 7.22
39 INT82881 Regulation of Ccl2 19 0.57 15.29 7.19
40 INT93144 Gene_expression of CCR1 18 0.75 14.69 6.84
41 INT81493 Transcription of CCL2 20 0.65 13.63 6.78
42 INT120895 Binding of CCL2 22 0.37 15.86 6.55
43 INT141611 Positive_regulation of Gene_expression of Ccr1 25 0.69 20.32 6.42
44 INT92504 Negative_regulation of Ccl2 17 0.43 8.98 6.29
45 INT92470 Negative_regulation of Gene_expression of CCL5 15 0.50 5.46 5.86
46 INT136309 Positive_regulation of Cxcl12 24 0.62 12.45 5.58
47 INT83290 Regulation of Gene_expression of Ccl2 8 0.59 9.06 5.56
48 INT140223 Regulation of Ccl2 15 0.45 13.1 5.41
49 INT181022 Binding of Ccr1 15 0.37 10.69 5.37
50 INT161220 Binding of Ccl2 17 0.46 17.63 4.94
51 INT150237 Localization of Ccr1 10 0.75 9.25 4.72
52 INT103073 Positive_regulation of Positive_regulation of Ccl2 10 0.50 6.74 4.7
53 INT96851 Negative_regulation of Localization of CCL2 14 0.53 5.98 4.57
54 INT4239 Negative_regulation of CCL5 15 0.40 10.92 4.26
55 INT161221 Positive_regulation of Positive_regulation of Ccr2 3 0.50 4.55 3.98
56 INT65700 Localization of CCR1 7 0.51 4 3.91
57 INT121661 Binding of CXCL12 25 0.37 11.27 3.82
58 INT181347 Gene_expression of Cxcl13 9 0.63 9.08 3.75
59 INT253983 Binding of Cxcl12 8 0.43 5.33 3.71
60 INT222241 Binding of Ccr2 5 0.42 4.09 3.71
61 INT103281 Transcription of CCL5 10 0.67 5.95 3.7
62 INT117518 Transcription of Ccl2 12 0.68 11.12 3.61
63 INT130646 Regulation of CXCL12 14 0.47 7.67 3.48
64 INT124123 Positive_regulation of Localization of CCL5 12 0.67 7 3.37
65 INT281144 Regulation of Gene_expression of Ccr2 2 0.44 2.38 3.29
66 INT181355 Regulation of Gene_expression of Ccl2 12 0.44 10.37 3.21
67 INT78898 Regulation of Gene_expression of CCL5 9 0.42 5.7 3.11
68 INT135409 Transcription of Ccl2 13 0.62 10.59 3.06
69 INT120067 Positive_regulation of Gene_expression of CCR2 10 0.46 5.13 3.02
70 INT222237 Negative_regulation of Gene_expression of Ccr2 3 0.37 3.39 2.91
71 INT181386 Positive_regulation of Cxcl12 12 0.69 15.35 2.84
72 INT151436 Regulation of Ccr2 4 0.44 2.81 2.82
73 INT194661 Binding of CCL5 9 0.46 6.07 2.73
74 INT222226 Negative_regulation of Ccr2 6 0.57 3.69 2.66
75 INT253982 Positive_regulation of Binding of Cxcl12 1 0.45 3.85 2.6
76 INT117519 Positive_regulation of Transcription of Ccl2 5 0.49 6.01 2.54
77 INT130638 Regulation of Cxcl12 6 0.34 2.91 2.44
78 INT121659 Positive_regulation of CXCL12 8 0.53 9.17 2.36
79 INT108482 Positive_regulation of Gene_expression of CXCL12 7 0.53 9.72 2.36
80 INT82880 Positive_regulation of Localization of Ccl2 4 0.49 2.65 2.31
81 INT23588 Positive_regulation of CCR1 6 0.67 4.44 2.24
82 INT220178 Positive_regulation of Cxcl13 5 0.42 5.98 2.21
83 INT146504 Regulation of Ccr2 5 0.39 3.58 2.21
84 INT181402 Negative_regulation of Ccr1 8 0.42 7 2.2
85 INT113906 Regulation of Positive_regulation of CCL2 4 0.27 3.2 2.17
86 INT222230 Positive_regulation of Gene_expression of Cxcl12 11 0.59 5.26 2.13
87 INT128993 Negative_regulation of Localization of Ccl2 1 0.42 1.5 2.1
88 INT154751 Positive_regulation of Positive_regulation of Ccl2 2 0.48 2.43 2.06
89 INT113907 Regulation of Localization of CCL2 5 0.62 2.46 2.05
90 INT297679 Positive_regulation of Gene_expression of Cxcl12 6 0.69 8.02 2.02
91 INT100490 Negative_regulation of Positive_regulation of CCL2 6 0.23 1.48 1.96
92 INT112970 Regulation of Ccr1 8 0.29 7.77 1.93
93 INT67980 Positive_regulation of Positive_regulation of CCL2 7 0.49 5.89 1.85
94 INT181341 Binding of Ccr2 8 0.32 6.47 1.77
95 INT194660 Positive_regulation of Binding of CCL5 1 0.42 2.74 1.72
96 INT253972 Positive_regulation of Positive_regulation of Cxcl12 1 0.45 3.22 1.71
97 INT102550 Positive_regulation of Gene_expression of Ccr2 6 0.69 4.53 1.67
98 INT113110 Negative_regulation of CXCL12 8 0.43 6.01 1.63
99 INT78896 Negative_regulation of Localization of CCL5 8 0.57 2.43 1.59
100 INT222227 Localization of Cxcl12 5 0.64 1.61 1.59
101 INT171015 Positive_regulation of Positive_regulation of CCL5 3 0.42 3.63 1.51
102 INT254252 Localization of Cxcl12 9 0.76 7.17 1.49
103 INT181373 Negative_regulation of Gene_expression of Ccr2 5 0.59 5.92 1.44
104 INT322712 Negative_regulation of Binding of Ccl2 4 0.32 1.29 1.44
105 INT130647 Regulation of Gene_expression of CXCL12 6 0.39 5.01 1.38
106 INT245089 Localization of CXCL12 8 0.65 10.17 1.28
107 INT78692 Regulation of PTK2B 2 0.47 0.29 1.28
108 INT81497 Positive_regulation of Transcription of CCL2 4 0.63 2 1.25
109 INT228772 Positive_regulation of Localization of Ccl2 3 0.48 4.23 1.21
110 INT281139 Phosphorylation of Ccr2 2 0.79 1.2 1.18
111 INT281141 Positive_regulation of Phosphorylation of Ccr2 2 0.49 1.2 1.18
112 INT268754 Negative_regulation of Gene_expression of Ccr1 5 0.43 2.76 1.13
113 INT284546 Positive_regulation of Cxcr7 5 0.29 6.73 1.13
114 INT62959 Positive_regulation of CCR2 4 0.61 1.47 1.13
115 INT222235 Localization of Ccr2 7 0.73 5.32 1.12
116 INT158242 Negative_regulation of Gene_expression of CCR2 3 0.37 2.13 1.12
117 INT236945 Positive_regulation of Gene_expression of Cxcl13 3 0.38 3.98 1.11
118 INT294735 Positive_regulation of Binding of Ccl2 2 0.34 0.69 1.11
119 INT151435 Negative_regulation of Positive_regulation of Ccr2 1 0.53 0.7 1.08
120 INT194657 Negative_regulation of CCR2 2 0.29 2.3 1.07
121 INT211294 Binding of Cxcl12 4 0.45 2.89 1.05
122 INT291366 Binding of CXCR7 4 0.18 1.64 1.03
123 INT268753 Negative_regulation of Positive_regulation of Ccr1 1 0.42 2.59 0.96
124 INT275510 Negative_regulation of Binding of Ccl2 3 0.32 1.47 0.93
125 INT222231 Transcription of Cxcl12 4 0.55 2.25 0.91
126 INT103285 Regulation of Localization of CCL5 3 0.44 1.11 0.89
127 INT236947 Transcription of Cxcl13 2 0.43 1.74 0.84
128 INT146567 Negative_regulation of Negative_regulation of Ccl2 1 0.43 1.72 0.83
129 INT161223 Negative_regulation of Positive_regulation of Ccr2 1 0.43 0.83 0.81
130 INT181359 Transcription of Ccr1 4 0.53 1.66 0.8
131 INT117552 Regulation of Regulation of CCL2 1 0.13 0.57 0.8
132 INT268746 Positive_regulation of Binding of Ccr1 1 0.50 1.81 0.79
133 INT148839 Regulation of Gene_expression of CCR2 2 0.26 1.78 0.76
134 INT222239 Transcription of Ccr2 2 0.61 1.15 0.73
135 INT120010 Negative_regulation of Transcription of CCL2 1 0.02 0.99 0.72
136 INT300848 Negative_regulation of Cxcl12 3 0.40 2.29 0.69
137 INT136269 Transcription of CCR2 2 0.61 1.27 0.69
138 INT352413 Phosphorylation of Ccl2 1 0.42 0 0.69
139 INT181338 Regulation of Cxcl13 1 0.10 0.52 0.69
140 INT291371 Positive_regulation of Localization of CXCL12 2 0.35 2.8 0.65
141 INT136363 Negative_regulation of Positive_regulation of Ccl2 3 0.32 1.46 0.64
142 INT291368 Gene_expression of CXCR7 4 0.38 3.21 0.63
143 INT222998 Positive_regulation of Negative_regulation of CCL2 1 0.12 1.11 0.59
144 INT189481 Regulation of Gene_expression of Ccr1 3 0.45 1.97 0.58
145 INT333232 Negative_regulation of Gene_expression of Cxcl12 4 0.42 3.35 0.57
146 INT284539 Positive_regulation of Positive_regulation of Cxcr7 2 0.21 2.64 0.56
147 INT172297 Binding of CCR1 1 0.36 0.08 0.56
148 INT102776 Phosphorylation of CCL2 1 0.65 1.55 0.56
149 INT222238 Regulation of Localization of Cxcl12 1 0.22 0.6 0.55
150 INT97637 Positive_regulation of Localization of CCR1 1 0.08 0.51 0.55
151 INT239551 Binding of CCR2 2 0.39 0 0.52
152 INT222242 Positive_regulation of Transcription of Ccr2 1 0.44 0.66 0.52
153 INT136310 Negative_regulation of Cxcl12 3 0.37 3.29 0.51
154 INT302877 Regulation of Localization of Ccl2 2 0.19 1.08 0.49
155 INT236350 Transcription of Ccr2 2 0.72 3.59 0.49
156 INT236944 Positive_regulation of Transcription of Cxcl13 1 0.38 1.13 0.49
157 INT280914 Positive_regulation of Localization of Cxcl12 3 0.44 3.99 0.47
158 INT291367 Negative_regulation of Gene_expression of CXCL12 3 0.32 4.15 0.47
159 INT182225 Transcription of CCR1 1 0.57 0.45 0.47
160 INT281148 Negative_regulation of Transcription of Cxcl12 1 0.26 1.12 0.47
161 INT281138 Regulation of Binding of Ccl2 1 0.07 0.92 0.47
162 INT281140 Regulation of Binding of Cxcl12 1 0.28 0.93 0.47
163 INT272877 Localization of Ccr2 2 0.75 1.68 0.46
164 INT290397 Positive_regulation of Binding of CCL2 1 0.22 0.99 0.46
165 INT281147 Regulation of Binding of Ccr2 1 0.39 0.86 0.46
166 INT281149 Positive_regulation of Localization of Cxcl12 1 0.31 0.42 0.45
167 INT82742 Gene_expression of Tff2 3 0.75 7.06 0.44
168 INT194658 Positive_regulation of Transcription of CCL5 1 0.45 0.68 0.44
169 INT109920 Positive_regulation of PTK2B 5 0.43 2.21 0.43
170 INT267606 Protein_catabolism of CCL5 2 0.48 1.39 0.43
171 INT119574 Regulation of Regulation of Ccl2 1 0.04 0.35 0.43
172 INT134259 Negative_regulation of Transcription of Ccl2 2 0.11 0.93 0.42
173 INT355681 Negative_regulation of Transcription of Ccl2 1 0.33 1 0.42
174 INT109922 Negative_regulation of PTK2B 3 0.26 1.63 0.39
175 INT268761 Positive_regulation of Positive_regulation of Ccr1 1 0.43 1.51 0.39
176 INT163905 Positive_regulation of Positive_regulation of Ccr2 1 0.13 0.16 0.37
177 INT171023 Negative_regulation of Gene_expression of CCR1 2 0.37 1.53 0.36
178 INT340642 Regulation of Gene_expression of Ccr2 1 0.62 2.26 0.35
179 INT109919 Positive_regulation of Positive_regulation of PTK2B 1 0.31 0.09 0.35
180 INT284548 Binding of Cxcr7 4 0.21 2.15 0.33
181 INT195733 Phosphorylation of CCL5 2 0.10 1.04 0.33
182 INT103283 Negative_regulation of Transcription of CCL5 1 0.50 0.28 0.27
183 INT181417 Positive_regulation of Transcription of Ccl2 2 0.45 1.8 0.26
184 INT171025 Negative_regulation of Localization of CCR1 1 0.37 0.4 0.25
185 INT274228 Positive_regulation of Positive_regulation of Cxcl12 4 0.44 2.82 0.23
186 INT268747 Positive_regulation of Localization of Ccr1 1 0.43 0.8 0.23
187 INT136270 Positive_regulation of Transcription of CCR2 1 0.09 0.82 0.22
188 INT282377 Regulation of Positive_regulation of CCL5 1 0.05 1.12 0.22
189 INT333209 Gene_expression of Cxcr7 5 0.46 2.54 0.21
190 INT268750 Positive_regulation of Transcription of Ccr1 2 0.46 0.26 0.21
191 INT158246 Phosphorylation of CCR2 1 0.55 0.32 0.21
192 INT299139 Positive_regulation of Transcription of Cxcl12 1 0.37 0.28 0.21
193 INT245087 Transcription of CXCL12 2 0.46 2.04 0.2
194 INT89400 Phosphorylation of PTK2B 4 0.38 1.16 0.19
195 INT333239 Regulation of Gene_expression of Cxcl12 1 0.43 3.48 0.19
196 INT23591 Regulation of CCR1 1 0.26 0.96 0.19
197 INT268764 Regulation of Positive_regulation of Ccr1 1 0.45 0.83 0.18
198 INT236353 Regulation of Transcription of Ccl2 1 0.36 2.12 0.18
199 INT181340 Negative_regulation of Negative_regulation of Ccr1 1 0.28 0.67 0.18
200 INT236954 Binding of Cxcl13 1 0.29 1.13 0.17
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