GO:0070106

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Name interleukin-27-mediated signaling pathway
Categary Process
Go Slim No
Go Link GO:0070106
Unique Molecular Interactions 20
Total Molecular Interactions 39
Total Single Events 115
Pain Genes Associated 2

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for interleukin-27-mediated signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for interleukin-27-mediated signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT126717 Binding of Il6 and Il6st 3 0.21 3.35 2.22
2 INT333966 Binding of Il6r and Il6st 1 0.01 1.74 1.1
3 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01
4 INT286798 Binding of Il6st and Cntf 1 0.10 1.34 0.97
5 INT328821 Binding of Il6st and Jak1 1 0.05 0 0.38
6 INT328827 Binding of Jak2 and Il6st 1 0.05 0 0.38
7 INT328824 Binding of Il6st and TYK2 1 0.02 0 0.38
8 INT188200 IL6ST Positive_regulation of STAT3 1 0.25 0.38 0.23
9 INT258399 Binding of IL6R and IL6ST 1 0.06 0.61 0.18
10 INT128221 Binding of IL6ST and Il6 2 0.00 0.73 0.17
11 INT206081 IL6ST Negative_regulation of IL6 1 0.11 0.81 0.17
12 INT355009 Cntf Positive_regulation of Il6st 1 0.02 0.69 0.08
13 INT355010 Lif Positive_regulation of Il6st 1 0.02 0.69 0.08
14 INT294316 IL6ST Positive_regulation of Gene_expression of IL11 1 0.22 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for interleukin-27-mediated signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in interleukin-27-mediated signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT89986 Gene_expression of Il6st 5 0.56 2.35 3.15
2 INT172186 Gene_expression of IL6ST 20 0.75 11.63 2.67
3 INT253403 Positive_regulation of Il6st 2 0.28 2.07 1.54
4 INT133422 Binding of IL6ST 10 0.40 4.9 1.49
5 INT159009 Regulation of Il6st 2 0.18 2 1.41
6 INT75923 Positive_regulation of IL6ST 5 0.45 2.49 1.21
7 INT333965 Binding of Il6st 1 0.08 0.9 0.65
8 INT188230 Negative_regulation of IL6ST 3 0.33 0.49 0.45
9 INT136518 Regulation of IL6ST 2 0.29 0.31 0.36
10 INT126195 Transcription of Il6st 1 0.39 0.2 0.28
11 INT136520 Positive_regulation of Regulation of IL6ST 1 0.09 0.08 0.13
12 INT299517 Positive_regulation of Gene_expression of Il6st 1 0.06 0.23 0.09
13 INT206151 Positive_regulation of Gene_expression of IL6ST 2 0.24 0.35 0.06
14 INT294329 Regulation of Gene_expression of IL6ST 1 0.22 0 0.05
15 INT253389 Positive_regulation of Positive_regulation of Il6st 1 0.28 0.07 0.05
16 INT294344 Localization of IL6ST 1 0.39 0 0.04
17 INT206153 Phosphorylation of IL6ST 1 0.22 0.05 0
18 INT206156 Positive_regulation of Phosphorylation of IL6ST 1 0.14 0.05 0
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