GO:0070207

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Name protein homotrimerization
Categary Process
Go Slim No
Go Link GO:0070207
Unique Molecular Interactions 177
Total Molecular Interactions 275
Total Single Events 2876
Pain Genes Associated 25

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for protein homotrimerization. They are ordered first by their pain relevance and then by number of times they were reported for protein homotrimerization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT254001 Binding of Cxcr4 and Mif 1 0.52 14.17 7.18
2 INT253988 Binding of Cd74 and Mif 1 0.36 6.57 2.52
3 INT283050 Binding of Gad2 and Trpm8 1 0.23 2.02 1.93
4 INT203149 Binding of Mif and Osm 1 0.02 2.93 1.78
5 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55
6 INT283426 Binding of Lcn2 and Nt5e 1 0.08 5.8 1.24
7 INT253999 Binding of Cxcl12 and Mif 1 0.41 2.26 1.22
8 INT203168 PTGER2 Negative_regulation of Gene_expression of ALOX5AP 1 0.03 2.4 1.18
9 INT353338 F2r Positive_regulation of Localization of Mif 1 0.68 1.25 1.16
10 INT134384 Trpa1 Negative_regulation of Gene_expression of Trpm8 1 0.47 1.21 1.02
11 INT203162 PTGER2 Regulation of Gene_expression of ALOX5AP 1 0.04 1.47 0.94
12 INT40636 Mif Negative_regulation of Pomc 1 0.25 0.07 0.9
13 INT253992 Cxcl12 Positive_regulation of Mif 1 0.46 1.31 0.88
14 INT203148 Mif Positive_regulation of Gene_expression of S100a8 1 0.00 1.56 0.87
15 INT44503 Cubn Positive_regulation of Prl 1 0.18 0 0.74
16 INT312101 ELANE Regulation of ALOX5AP 1 0.21 1.11 0.73
17 INT40703 Mif Negative_regulation of Negative_regulation of POMC 1 0.24 0.49 0.7
18 INT253994 Cyp3a23/3a1 Positive_regulation of Localization of Mif 1 0.09 0.96 0.69
19 INT164286 Alox5ap Positive_regulation of Cysltr2 1 0.19 1.11 0.61
20 INT164990 Mif Positive_regulation of Gene_expression of Grina 1 0.24 0.53 0.6
21 INT164284 Ltb4r Positive_regulation of Alox5ap 1 0.34 1.1 0.6
22 INT195773 Binding of Cd74 and Mif 2 0.25 2.78 0.55
23 INT254197 Mif Regulation of Ptgs2 1 0.02 1.08 0.55
24 INT254200 Mif Regulation of Trp53 1 0.02 0.96 0.52
25 INT283434 Lcn2 Positive_regulation of Localization of IL8 1 0.07 1.33 0.51
26 INT330543 Prkcg Regulation of Regulation of Trpm8 1 0.11 0.28 0.47
27 INT195769 MIF Regulation of Gene_expression of TP53I11 1 0.19 1.24 0.47
28 INT296114 Il4 Regulation of Gene_expression of Arg1 1 0.00 0.65 0.46
29 INT253997 Binding of Cd200r1 and Mif 1 0.03 1.02 0.46
30 INT195774 Binding of MIF and Cd74 1 0.02 1.15 0.46
31 INT355571 MIF Positive_regulation of IL8 1 0.04 1.05 0.44
32 INT355568 MIF Positive_regulation of IL6 1 0.05 1.05 0.44
33 INT121364 ZNF398 Negative_regulation of Transcription of MIF 1 0.00 0.9 0.43
34 INT296237 Anxa1 Regulation of Gene_expression of Trpm8 1 0.03 0.57 0.43
35 INT183139 Negative_regulation of Dctn6 Positive_regulation of Trpm8 1 0.01 0 0.43
36 INT121378 Fancl Positive_regulation of MIF 1 0.01 0.92 0.42
37 INT331927 Ptger2 Positive_regulation of Arg1 1 0.06 1.8 0.42
38 INT296235 Trpm8 Regulation of Positive_regulation of Anxa1 1 0.03 0.62 0.41
39 INT108732 Gene_expression of Gstp1 Positive_regulation of Gene_expression of Mgst1 1 0.44 0.58 0.41
40 INT38269 Binding of TCN1 and CUBN 1 0.00 0.28 0.4
41 INT203167 Gene_expression of PTGER2 Positive_regulation of Gene_expression of ALOX5AP 1 0.03 0.67 0.38
42 INT121365 ZNF398 Negative_regulation of Gene_expression of MIF 1 0.00 0.73 0.38
43 INT230584 Positive_regulation of Trpv1 Positive_regulation of Trpm8 1 0.28 0.16 0.37
44 INT263072 Kncn Regulation of Transcription of Trpm8 1 0.08 0.99 0.36
45 INT355570 MIF Positive_regulation of Gene_expression of IL8 1 0.07 1.11 0.36
46 INT230585 Trpv1 Positive_regulation of Trpm8 1 0.28 0.15 0.36
47 INT312102 Binding of ALOX5 and ALOX5AP 1 0.10 0.65 0.36
48 INT32212 POMC Regulation of Gene_expression of Mif 1 0.00 1.01 0.35
49 INT72953 Mif Positive_regulation of Localization of Prl 1 0.42 0 0.34
50 INT353333 Positive_regulation of F2r Positive_regulation of Localization of Mif 1 0.46 0.26 0.32
51 INT72951 Mif Regulation of Prl 1 0.41 0 0.32
52 INT353334 F2r Positive_regulation of Mif 1 0.68 0 0.32
53 INT353335 F2r Regulation of Positive_regulation of Mif 1 0.27 0.11 0.31
54 INT337085 Binding of Cxcr4 and Mif 1 0.21 1.89 0.3
55 INT353336 F2r Regulation of Localization of Mif 1 0.23 0.24 0.28
56 INT221918 TRPV4 Positive_regulation of TRPM8 1 0.05 0 0.28
57 INT72952 Mif Regulation of Localization of Prl 1 0.28 0 0.27
58 INT254000 Regulation of Binding of Cxcr4 and Mif 1 0.29 0.56 0.27
59 INT45196 Cubn Negative_regulation of Prl 1 0.05 0 0.27
60 INT353330 F2r Positive_regulation of Positive_regulation of Mif 1 0.46 0 0.26
61 INT337086 Mif Negative_regulation of Localization of Trp53 1 0.16 1.64 0.25
62 INT355567 IRF6 Positive_regulation of MIF 1 0.01 0.29 0.25
63 INT337091 Mif Negative_regulation of Positive_regulation of Trp53 1 0.16 1.64 0.25
64 INT56633 Gusb Regulation of Mgst1 1 0.03 0.06 0.24
65 INT56632 Ugt2b17 Regulation of Mgst1 1 0.04 0.06 0.24
66 INT261842 Pla2g6 Positive_regulation of Trpm8 1 0.03 0 0.23
67 INT242595 Trpm8 Negative_regulation of Trpv1 1 0.24 0 0.23
68 INT111313 IL36RN Positive_regulation of Gene_expression of MGST1 1 0.07 0.66 0.22
69 INT330546 Positive_regulation of Trpm8 Positive_regulation of Positive_regulation of Ca2 1 0.13 0.67 0.22
70 INT283431 Lcn2 Regulation of Gene_expression of Cxcr1 1 0.01 0.22 0.2
71 INT326737 IL8 Positive_regulation of Gene_expression of ARG1 1 0.38 2.41 0.19
72 INT312091 ALOX5AP Regulation of Transcription of ALOX5 1 0.13 0.37 0.18
73 INT198649 Binding of HIF1A and MIF 1 0.01 1.53 0.18
74 INT75039 Slc6a14 Positive_regulation of Gene_expression of Mgst1 1 0.01 0.17 0.17
75 INT331768 Binding of Arg1 and NOSTRIN 1 0.01 0.6 0.17
76 INT142224 Urb1 Negative_regulation of Trpm8 1 0.03 0.1 0.17
77 INT331766 Binding of Arg1 and Nos2 1 0.17 0.6 0.17
78 INT142223 Trpa1 Negative_regulation of Trpm8 1 0.20 0.1 0.17
79 INT312089 LTB4R Positive_regulation of ALOX5AP 1 0.01 0.32 0.16
80 INT312126 ELANE Positive_regulation of ALOX5AP 1 0.20 0.25 0.15
81 INT316249 DBT Regulation of TRPM8 1 0.08 1.28 0.15
82 INT283428 Negative_regulation of Binding of Lcn2 and Nt5e 1 0.06 1.09 0.15
83 INT324874 Positive_regulation of Tlr2 Positive_regulation of Gene_expression of Mif 1 0.05 0.66 0.15
84 INT324860 Tlr2 Positive_regulation of Gene_expression of Mif 1 0.05 0.66 0.15
85 INT195770 Binding of CPB1 and MIF 1 0.01 0.47 0.15
86 INT326735 Negative_regulation of IL8 Negative_regulation of Gene_expression of ARG1 1 0.32 0.33 0.14
87 INT254002 Binding of Cyp3a23/3a1 and Positive_regulation of Gene_expression of Mif 1 0.08 0.56 0.13
88 INT296238 Trpm8 Regulation of Trpa1 1 0.30 0.21 0.12
89 INT296234 Trpm8 Regulation of Pla2g6 1 0.18 0.21 0.12
90 INT204883 gr Negative_regulation of Lcn2 1 0.07 0.15 0.11
91 INT151094 Binding of TRPA1 and TRPM8 1 0.41 0.2 0.1
92 INT312116 Negative_regulation of PTGER2 Regulation of Gene_expression of ALOX5AP 1 0.04 0.2 0.1
93 INT139581 Binding of Atrn and Negative_regulation of Trpm8 1 0.01 0 0.09
94 INT222425 Mif Regulation of Tlr4 1 0.01 0.24 0.09
95 INT283427 Lcn2 Positive_regulation of Nt5e 1 0.08 0.21 0.09
96 INT251569 Binding of Ripk1 and Traf2 1 0.12 0.67 0.08
97 INT337090 Mif Positive_regulation of Gene_expression of Mapk1 1 0.10 1.11 0.08
98 INT313503 Binding of ALOX5AP and CXADRP1 1 0.01 1.51 0.08
99 INT337087 Negative_regulation of Binding of Mif and Cops5 1 0.13 1.64 0.08
100 INT312093 ELANE Regulation of Gene_expression of ALOX5AP 1 0.13 0.15 0.08
101 INT222514 Mif Regulation of Localization of Il6 1 0.04 0.23 0.08
102 INT337088 Binding of Mif and Cops5 1 0.12 1.63 0.08
103 INT337084 Negative_regulation of Binding of Cd74 and Mif 1 0.29 1.64 0.08
104 INT345292 Binding of Lcn2 and Havcr1 1 0.00 1.17 0.07
105 INT312113 ELANE Positive_regulation of Gene_expression of ALOX5AP 1 0.23 0.14 0.07
106 INT283425 Lcn2 Positive_regulation of Gene_expression of Nt5e 1 0.07 0.13 0.07
107 INT345297 Binding of NAGLU and Lcn2 1 0.01 1.24 0.07
108 INT330542 Prkaca Regulation of Regulation of Trpm8 1 0.03 0.1 0.05
109 INT296236 Anxa1 Positive_regulation of Trpm8 1 0.04 0.09 0.05
110 INT316248 ESR1 Regulation of Gene_expression of TRPM8 1 0.34 0.17 0.05
111 INT331924 Binding of Arg1 and Actvty1 1 0.03 1.11 0.05
112 INT307157 Berr1 Regulation of Mgst1 1 0.00 1.51 0.05
113 INT313504 Binding of ALOX5AP and SNRNP70 1 0.04 0.5 0.05
114 INT353341 F2r Positive_regulation of Negative_regulation of Mif 1 0.49 0 0.05
115 INT190095 Negative_regulation of Binding of Hivep3 and Traf2 1 0.15 0.08 0.04
116 INT190096 Binding of Hivep3 and Traf2 1 0.17 0.08 0.04
117 INT296232 Anxa1 Regulation of Trpm8 1 0.03 0.54 0.04
118 INT312117 Negative_regulation of ELANE Positive_regulation of ALOX5AP 1 0.17 0.08 0.04
119 INT348526 Binding of TRAF2 and EDAR 1 0.15 0.52 0.03
120 INT348538 Binding of TRAF2 and EDARADD 1 0.06 0.53 0.03
121 INT321178 Binding of Ntrk2 and Mgst1 1 0.07 0 0.03
122 INT313551 Binding of ALOX5AP and Cor 1 0.02 1.01 0.03
123 INT326742 AR Regulation of Gene_expression of ARG1 1 0.24 0.43 0.03
124 INT292553 Binding of TRAF2 and TRADD 1 0.09 0.1 0
125 INT292560 Binding of TNFRSF1A and TRAF2 1 0.08 0.09 0
126 INT121545 Mif Negative_regulation of Regulation of Ptgs2 1 0.13 0.15 0
127 INT151092 BPHL Regulation of Gene_expression of TRPM8 1 0.05 0 0
128 INT290811 Binding of Mgst1 and Gsk3b 1 0.05 0 0
129 INT158907 Ogt Negative_regulation of Gene_expression of Ada 1 0.44 0 0
130 INT269937 Binding of Smad3 and Mgst1 1 0.09 0 0
131 INT197677 Binding of ESR1 and Arg1 1 0.04 0 0
132 INT326744 ARG1 Regulation of ARG2 1 0.50 1.04 0
133 INT127731 Binding of A2m and Mif 1 0.19 0 0
134 INT254745 Binding of Anxa3 and Skil 1 0.00 0 0
135 INT348521 TRAF2 Positive_regulation of MAP3K1 1 0.03 0.46 0
136 INT151093 BCL2L10 Regulation of Gene_expression of TRPM8 1 0.20 0 0
137 INT280969 Binding of Cav3 and Mgst1 1 0.01 0 0
138 INT313499 Binding of ALOX5AP and CRP 1 0.07 0.45 0
139 INT269928 Binding of Sox17 and Mgst1 1 0.12 0 0
140 INT249960 Arg1 Negative_regulation of NOS1 1 0.01 0.1 0
141 INT254747 Positive_regulation of Binding of Skil and Fig4 1 0.03 0.14 0
142 INT253993 Positive_regulation of Binding of Cxcr4 and Mif 1 0.50 0 0
143 INT348528 TRAF2 Positive_regulation of Positive_regulation of CASP8 1 0.02 0.44 0
144 INT285389 Binding of Ppara and Mgst1 1 0.11 0.22 0
145 INT257666 Binding of Mgst1 and Pard3 1 0.05 0 0
146 INT313502 Binding of ALOX5AP and ADIPOQ 1 0.05 0.44 0
147 INT283002 Binding of Bak1 and Mgst1 1 0.01 0.24 0
148 INT146469 Otc Regulation of Cp 1 0.10 0.23 0
149 INT197675 Regulation of Binding of ESR1 and Arg1 1 0.05 0 0
150 INT326743 Gene_expression of AR Negative_regulation of Gene_expression of ARG1 1 0.32 0.8 0
151 INT334491 Binding of GCN1L1 and Mgst1 1 0.08 0 0
152 INT316250 Negative_regulation of DBT Negative_regulation of Gene_expression of TRPM8 1 0.11 1.06 0
153 INT326738 Gene_expression of IL8 Positive_regulation of Gene_expression of ARG1 1 0.26 0.41 0
154 INT159977 Binding of Mgst1 and Gnat3 1 0.03 0 0
155 INT222870 Traf2 Positive_regulation of Chuk 1 0.03 0.37 0
156 INT254746 Binding of Skil and Fig4 1 0.02 0.14 0
157 INT254748 Binding of Fig4 and Regulation of Skil 1 0.02 0.53 0
158 INT298871 ALOX5AP Positive_regulation of RAB7A 1 0.09 0.35 0
159 INT127732 Binding of Mif and Ilf3 1 0.10 0 0
160 INT286770 Skil Negative_regulation of Egr1 1 0.08 0.75 0
161 INT326748 IL8 Positive_regulation of ARG1 1 0.26 0.26 0
162 INT353337 F2r Positive_regulation of Gene_expression of Mif 1 0.46 0 0
163 INT158906 Ogt Negative_regulation of Ada 1 0.33 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for protein homotrimerization. They are ordered first by their pain relevance and then by number of times they were reported in protein homotrimerization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT121416 Gene_expression of Trpm8 101 0.78 52.7 47.85
2 INT117632 Gene_expression of Trpm8 99 0.78 29.41 30.9
3 INT116737 Localization of Mif 63 0.81 52.97 28.11
4 INT117600 Positive_regulation of Trpm8 65 0.70 31.96 24.46
5 INT101592 Gene_expression of TRPM8 82 0.78 70.61 22.89
6 INT40750 Gene_expression of Mif 61 0.78 34.59 20.28
7 INT111416 Positive_regulation of Trpm8 65 0.70 14.62 17.13
8 INT116736 Positive_regulation of Mif 40 0.70 31.93 15.37
9 INT195414 Gene_expression of ALOX5AP 65 0.72 31.22 15.25
10 INT94051 Positive_regulation of Arg1 41 0.60 36.22 13.72
11 INT233113 Regulation of Trpm8 24 0.61 18.08 13.17
12 INT2385 Gene_expression of MIF 57 0.68 40.74 12.78
13 INT83894 Positive_regulation of TRPM8 37 0.70 18.28 11.7
14 INT72949 Binding of Mif 31 0.46 23.12 11.65
15 INT143767 Negative_regulation of Trpm8 26 0.58 12.34 10.83
16 INT8249 Positive_regulation of Cubn 15 0.66 4.05 9.35
17 INT13893 Negative_regulation of Cubn 9 0.36 1.78 9.24
18 INT117553 Regulation of MIF 10 0.56 12.76 8.67
19 INT134381 Regulation of Trpm8 25 0.54 8.31 8.25
20 INT32210 Gene_expression of Mif 13 0.75 28.48 7.79
21 INT55091 Positive_regulation of Mgst1 35 0.69 10.77 6.88
22 INT517 Regulation of Mif 16 0.62 5.43 6.55
23 INT31598 Gene_expression of Mgst1 41 0.78 6.44 6.3
24 INT139580 Negative_regulation of Trpm8 19 0.58 3.8 6.26
25 INT94055 Gene_expression of Arg1 22 0.68 20.81 6.13
26 INT121370 Positive_regulation of MIF 22 0.70 17.79 6.08
27 INT516 Negative_regulation of Mif 13 0.59 6.69 6.08
28 INT146347 Negative_regulation of Gene_expression of Trpm8 9 0.55 6.96 5.42
29 INT159442 Positive_regulation of Gene_expression of Trpm8 10 0.70 5.86 5.34
30 INT83442 Negative_regulation of MIF 18 0.57 9.51 5.12
31 INT159443 Regulation of Gene_expression of Trpm8 9 0.57 6.63 5.12
32 INT174339 Positive_regulation of Localization of Mif 7 0.61 8.27 4.95
33 INT121372 Positive_regulation of Gene_expression of MIF 17 0.60 14.78 4.73
34 INT28030 Binding of Otc 5 0.37 2.72 4.3
35 INT101593 Positive_regulation of Gene_expression of TRPM8 16 0.70 13.79 4.23
36 INT115853 Transcription of Trpm8 15 0.68 7.72 4.1
37 INT116738 Positive_regulation of Gene_expression of Mif 14 0.68 10.99 3.8
38 INT120433 Regulation of TRPM8 11 0.62 8.56 3.78
39 INT130239 Transcription of Trpm8 10 0.66 2.83 3.74
40 INT18822 Regulation of Cubn 4 0.27 0.17 3.74
41 INT21869 Negative_regulation of Otc 16 0.58 8.43 3.67
42 INT142753 Gene_expression of Lcn2 28 0.76 10.03 3.62
43 INT45324 Positive_regulation of Otc 8 0.59 3.94 3.36
44 INT195415 Regulation of Gene_expression of ALOX5AP 10 0.45 6.43 3.13
45 INT255307 Phosphorylation of Mgst1 5 0.14 0.12 3.05
46 INT130226 Positive_regulation of Gene_expression of Mif 4 0.58 15.75 3.03
47 INT134378 Binding of Trpm8 8 0.48 1.74 2.95
48 INT127717 Negative_regulation of TRPM8 9 0.59 3.09 2.92
49 INT195421 Positive_regulation of Gene_expression of ALOX5AP 12 0.49 5.17 2.82
50 INT163290 Binding of MIF 9 0.31 7.57 2.8
51 INT203137 Binding of Mif 6 0.31 9.46 2.71
52 INT137967 Positive_regulation of Gene_expression of Trpm8 11 0.70 3.29 2.66
53 INT134377 Regulation of Gene_expression of Trpm8 7 0.59 3.18 2.66
54 INT151029 Positive_regulation of Gene_expression of Lcn2 8 0.68 4.04 2.65
55 INT55629 Regulation of Mgst1 12 0.53 2.7 2.62
56 INT120515 Gene_expression of Otc 13 0.66 4.33 2.6
57 INT120011 Localization of MIF 6 0.58 5.72 2.6
58 INT129161 Binding of TRPM8 7 0.48 1.32 2.48
59 INT136850 Positive_regulation of Arg1 10 0.50 6.96 2.47
60 INT40748 Negative_regulation of Mif 6 0.56 8.33 2.46
61 INT75004 Regulation of Gene_expression of Mgst1 3 0.61 0.72 2.44
62 INT138785 Gene_expression of Lcn2 9 0.56 9.88 2.41
63 INT117633 Localization of Trpm8 5 0.79 1.23 2.41
64 INT89166 Transcription of Mgst1 6 0.72 2 2.27
65 INT134380 Negative_regulation of Gene_expression of Trpm8 3 0.43 1.78 2.24
66 INT195191 Gene_expression of Cubn 2 0.06 0 2.17
67 INT127718 Regulation of Gene_expression of TRPM8 8 0.62 10.43 2.07
68 INT94050 Negative_regulation of Arg1 6 0.39 6.07 2.06
69 INT103304 Positive_regulation of Mif 6 0.48 8.66 2.05
70 INT151036 Positive_regulation of Lcn2 13 0.49 8.57 2
71 INT94056 Positive_regulation of Gene_expression of Arg1 8 0.60 6.57 1.95
72 INT244704 Gene_expression of ARG1 65 0.75 37.74 1.9
73 INT41633 Positive_regulation of Positive_regulation of Cubn 2 0.48 0.1 1.89
74 INT200779 Negative_regulation of Gene_expression of ALOX5AP 7 0.41 3.75 1.79
75 INT31599 Negative_regulation of Mgst1 14 0.59 5.35 1.72
76 INT164275 Gene_expression of Alox5ap 3 0.55 3.79 1.72
77 INT200778 Positive_regulation of ALOX5AP 3 0.49 2.54 1.7
78 INT44149 Regulation of Gene_expression of Mif 6 0.54 2.45 1.63
79 INT283399 Binding of Lcn2 1 0.47 5.48 1.61
80 INT138786 Positive_regulation of Lcn2 7 0.51 3.41 1.59
81 INT353326 Negative_regulation of Localization of Mif 1 0.45 1.28 1.59
82 INT94054 Regulation of Arg1 5 0.47 5.37 1.57
83 INT89167 Positive_regulation of Gene_expression of Mgst1 11 0.69 2.09 1.53
84 INT123198 Localization of TRPM8 6 0.81 3.24 1.53
85 INT122204 Positive_regulation of Alox5ap 1 0.26 0.23 1.53
86 INT130241 Positive_regulation of Positive_regulation of Trpm8 5 0.69 0.15 1.45
87 INT138782 Negative_regulation of Lcn2 3 0.31 1.21 1.34
88 INT151038 Localization of Lcn2 4 0.79 1.87 1.32
89 INT110942 Transcription of TRPM8 16 0.69 13.69 1.31
90 INT190067 Binding of Traf2 5 0.20 3.28 1.27
91 INT253987 Regulation of Localization of Mif 3 0.43 1.65 1.27
92 INT195134 Binding of Trpm8 5 0.37 0.82 1.26
93 INT41418 Regulation of Mif 2 0.40 3.86 1.24
94 INT146755 Regulation of Lcn2 6 0.26 2.5 1.22
95 INT257952 Positive_regulation of CUBN 1 0.07 0.61 1.22
96 INT44498 Localization of Cubn 2 0.34 0.38 1.19
97 INT121368 Transcription of Mif 5 0.72 2.71 1.15
98 INT130246 Negative_regulation of Gene_expression of TRPM8 4 0.59 3.35 1.14
99 INT89164 Positive_regulation of Transcription of Mgst1 4 0.60 1.53 1.13
100 INT138784 Positive_regulation of Gene_expression of Lcn2 3 0.49 4.44 1.13
101 INT41333 Negative_regulation of Positive_regulation of Cubn 2 0.15 0.47 1.12
102 INT331764 Regulation of Gene_expression of Arg1 7 0.36 4.65 1.1
103 INT121375 Transcription of MIF 4 0.62 2.85 1.1
104 INT120514 Negative_regulation of Gene_expression of Otc 4 0.41 1.19 1.08
105 INT102827 Protein_catabolism of Mif 1 0.33 0 1.06
106 INT69442 Regulation of Otc 3 0.24 0.98 1.04
107 INT94053 Transcription of Arg1 5 0.46 3.11 1.02
108 INT59575 Gene_expression of MGST1 2 0.52 3.47 0.98
109 INT156727 Gene_expression of Arg1 4 0.44 2.1 0.97
110 INT151035 Negative_regulation of Lcn2 5 0.42 1.99 0.96
111 INT121369 Negative_regulation of Gene_expression of MIF 3 0.50 2.48 0.92
112 INT159898 Localization of Trpm8 4 0.74 1.33 0.9
113 INT121376 Negative_regulation of Transcription of MIF 3 0.37 2.26 0.87
114 INT68926 Binding of ALOX5AP 8 0.36 4.02 0.84
115 INT177387 Positive_regulation of TRAF2 3 0.26 1.44 0.84
116 INT353328 Regulation of Positive_regulation of Mif 1 0.40 0.89 0.81
117 INT263064 Regulation of Transcription of Trpm8 2 0.43 2.33 0.8
118 INT132043 Positive_regulation of Phosphorylation of TRPM8 1 0.40 0.52 0.8
119 INT132041 Phosphorylation of TRPM8 1 0.66 0.51 0.79
120 INT132042 Negative_regulation of Phosphorylation of TRPM8 1 0.35 0.52 0.79
121 INT44500 Regulation of Localization of Cubn 1 0.20 0 0.75
122 INT2108 Localization of Mif 5 0.77 2.7 0.73
123 INT257951 Localization of CUBN 1 0.07 0 0.71
124 INT257948 Binding of CUBN 1 0.05 0 0.7
125 INT148470 Negative_regulation of Transcription of Trpm8 1 0.38 0.28 0.68
126 INT330549 Regulation of Regulation of Trpm8 1 0.24 0.52 0.68
127 INT32209 Regulation of Gene_expression of Mif 3 0.59 3.41 0.66
128 INT130229 Regulation of Negative_regulation of Mif 1 0.39 1.36 0.66
129 INT353322 Negative_regulation of Positive_regulation of Mif 1 0.38 0.35 0.66
130 INT44148 Negative_regulation of Gene_expression of Mif 6 0.41 0.95 0.64
131 INT13894 Regulation of Negative_regulation of Cubn 1 0.13 0.09 0.63
132 INT112665 Gene_expression of TRAF2 3 0.29 3.97 0.61
133 INT164276 Localization of Alox5ap 1 0.61 1.1 0.6
134 INT154745 Protein_catabolism of Traf2 1 0.86 1.04 0.59
135 INT124269 Binding of Cubn 1 0.28 0.2 0.59
136 INT154750 Positive_regulation of Protein_catabolism of Traf2 1 0.60 1.05 0.59
137 INT294555 Negative_regulation of Traf2 1 0.06 1.24 0.58
138 INT143768 Negative_regulation of Positive_regulation of Trpm8 3 0.43 0.57 0.57
139 INT59576 Positive_regulation of Gene_expression of MGST1 2 0.34 2.07 0.54
140 INT190074 Positive_regulation of Traf2 1 0.19 0.37 0.52
141 INT337079 Negative_regulation of Gene_expression of Mif 1 0.41 4.17 0.51
142 INT55628 Negative_regulation of Regulation of Mgst1 1 0.43 0 0.51
143 INT94047 Negative_regulation of Gene_expression of Arg1 1 0.37 1.37 0.5
144 INT137968 Negative_regulation of Positive_regulation of Trpm8 5 0.43 0.9 0.49
145 INT128569 Regulation of Positive_regulation of Cubn 1 0.09 0 0.49
146 INT110165 Negative_regulation of Arg1 8 0.38 3.21 0.48
147 INT78460 Negative_regulation of Positive_regulation of Mgst1 1 0.43 0.39 0.47
148 INT139579 Positive_regulation of Negative_regulation of Trpm8 2 0.69 0.44 0.45
149 INT122205 Negative_regulation of Alox5ap 1 0.24 0 0.45
150 INT197674 Positive_regulation of Gene_expression of Arg1 2 0.33 0.63 0.44
151 INT326766 Positive_regulation of Gene_expression of ARG1 12 0.67 8.32 0.42
152 INT20056 Positive_regulation of MGST1 2 0.47 0.7 0.42
153 INT151030 Regulation of Gene_expression of Lcn2 1 0.41 0 0.42
154 INT168249 Localization of Lcn2 2 0.14 1.9 0.4
155 INT296112 Positive_regulation of Positive_regulation of Arg1 1 0.05 0.55 0.4
156 INT195416 Regulation of ALOX5AP 2 0.53 0.8 0.38
157 INT116735 Positive_regulation of Positive_regulation of Mif 1 0.70 0.61 0.38
158 INT136851 Regulation of Arg1 7 0.38 3.05 0.37
159 INT195413 Negative_regulation of ALOX5AP 5 0.37 1.39 0.37
160 INT330548 Positive_regulation of Regulation of Trpm8 1 0.41 0.67 0.36
161 INT111315 Regulation of Gene_expression of MGST1 1 0.42 1.04 0.34
162 INT94048 Positive_regulation of Positive_regulation of Arg1 2 0.44 1.91 0.32
163 INT253977 Positive_regulation of Binding of Mif 1 0.48 0.97 0.32
164 INT27399 Protein_catabolism of Arg1 1 0.64 0 0.31
165 INT17138 Positive_regulation of Skil 2 0.35 0.59 0.3
166 INT283406 Negative_regulation of Binding of Lcn2 1 0.42 0.98 0.3
167 INT121374 Regulation of Gene_expression of MIF 2 0.39 1.01 0.29
168 INT135079 Positive_regulation of Localization of Trpm8 1 0.49 0 0.29
169 INT330614 Positive_regulation of Transcription of Arg1 1 0.15 0.92 0.29
170 INT137669 Positive_regulation of Positive_regulation of Trpm8 2 0.50 0.32 0.28
171 INT37570 Localization of Otc 2 0.61 0.97 0.25
172 INT94052 Negative_regulation of Protein_catabolism of Arg1 1 0.37 0.69 0.25
173 INT94049 Protein_catabolism of Arg1 1 0.77 0.6 0.25
174 INT245281 Negative_regulation of Gene_expression of Lcn2 2 0.44 1.68 0.24
175 INT121366 Regulation of Transcription of Mif 1 0.02 0.61 0.24
176 INT121367 Negative_regulation of Transcription of Mif 1 0.02 0.59 0.24
177 INT314003 Negative_regulation of Positive_regulation of Arg1 1 0.13 0.63 0.23
178 INT287261 Negative_regulation of Binding of Trpm8 2 0.42 0.23 0.22
179 INT28031 Negative_regulation of Binding of Otc 1 0.43 0.36 0.22
180 INT203173 Localization of ALOX5AP 3 0.48 0.78 0.21
181 INT337077 Positive_regulation of Localization of Mif 1 0.58 0.96 0.21
182 INT259884 Negative_regulation of Binding of ALOX5AP 1 0.10 0.46 0.21
183 INT211657 Localization of Arg1 4 0.53 3.48 0.2
184 INT258055 Positive_regulation of ARG1 7 0.49 3.45 0.19
185 INT191340 Negative_regulation of Positive_regulation of TRPM8 1 0.43 0.73 0.19
186 INT312127 Positive_regulation of Positive_regulation of ALOX5AP 1 0.35 0.37 0.19
187 INT312137 Transcription of ALOX5AP 1 0.50 0.37 0.18
188 INT287260 Regulation of Negative_regulation of Trpm8 1 0.61 0 0.17
189 INT75003 Positive_regulation of Positive_regulation of Mgst1 1 0.08 0.18 0.17
190 INT54099 Protein_catabolism of Trpm8 1 0.54 0.17 0.17
191 INT252702 Binding of TRAF2 3 0.23 2.21 0.16
192 INT326763 Negative_regulation of ARG1 1 0.57 1.49 0.16
193 INT283040 Positive_regulation of Transcription of Trpm8 1 0.47 0.87 0.16
194 INT154744 Regulation of Protein_catabolism of Traf2 1 0.39 0.18 0.16
195 INT280717 Positive_regulation of Regulation of Arg1 1 0.12 0 0.16
196 INT255303 Localization of Mgst1 6 0.27 0.9 0.15
197 INT130247 Positive_regulation of Localization of TRPM8 1 0.50 0.15 0.15
198 INT159975 Positive_regulation of Gene_expression of Mgst1 1 0.45 0.14 0.14
199 INT260063 Positive_regulation of Positive_regulation of TRPM8 1 0.38 0 0.14
200 INT159974 Gene_expression of Mgst1 1 0.50 0.14 0.14
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