GO:0070215

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Name MDM2 binding
Categary Function
Go Slim No
Go Link GO:0070215
Unique Molecular Interactions 532
Total Molecular Interactions 676
Total Single Events 8634
Pain Genes Associated 12

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for MDM2 binding. They are ordered first by their pain relevance and then by number of times they were reported for MDM2 binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21
2 INT338167 Binding of CDKN2A and MC1R 1 0.42 6.14 5.76
3 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17
4 INT162163 CDKN2A Positive_regulation of PLD2 1 0.24 0 1.24
5 INT209926 IL1B Regulation of PPARA 1 0.21 2.45 1.2
6 INT202620 Binding of Ppara and Rxra 15 0.09 2.63 1.11
7 INT209923 IL17A Negative_regulation of PPARA 1 0.14 2.46 0.99
8 INT73461 PTPLA Positive_regulation of Transcription of TP53 1 0.06 0.99 0.96
9 INT330629 TP53 Negative_regulation of Gene_expression of Fos 1 0.30 1.76 0.94
10 INT330630 Binding of TP53 and Car1 1 0.23 1.56 0.86
11 INT97057 Bcl2l1 Regulation of Gene_expression of Trp53 1 0.36 0.51 0.83
12 INT97058 Cpz Regulation of Gene_expression of Trp53 1 0.27 0.57 0.83
13 INT97056 Cpz Regulation of Gene_expression of Bcl2l1 1 0.22 0.57 0.83
14 INT209859 IL4 Positive_regulation of PPARA 1 0.22 1.66 0.69
15 INT101986 TP53 Positive_regulation of Gene_expression of GDF15 1 0.52 2.45 0.67
16 INT114951 PPARA Positive_regulation of Gene_expression of RXRA 1 0.34 0.25 0.64
17 INT114950 YY1 Positive_regulation of Positive_regulation of PPARA 1 0.52 0.25 0.64
18 INT83800 Aap Regulation of Gene_expression of Bcl2l1 1 0.28 0.58 0.64
19 INT114948 NCOA1 Positive_regulation of Positive_regulation of PPARA 1 0.20 0.24 0.62
20 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 0.27 0.83 0.61
21 INT211993 Binding of Ppara and Rorb 1 0.00 1.13 0.54
22 INT103092 Binding of PPARA and ISYNA1 1 0.01 0.45 0.54
23 INT254200 Mif Regulation of Trp53 1 0.02 0.96 0.52
24 INT285688 Cpox Positive_regulation of PPARA 1 0.02 1 0.5
25 INT240441 Ltb4r1 Positive_regulation of PPARA 1 0.03 1.01 0.47
26 INT240442 Binding of PPARA and Ltb4r1 1 0.02 0.94 0.46
27 INT302829 Mapkapk5 Positive_regulation of Trp53 1 0.07 0.81 0.43
28 INT242992 Binding of Agt and Ppara 1 0.20 1.44 0.42
29 INT158032 Binding of CDKN2A and KRT20 1 0.28 0.59 0.4
30 INT238382 Il13 Positive_regulation of Gene_expression of Ppara 1 0.18 0.79 0.4
31 INT107706 PPARA Positive_regulation of Gene_expression of CPOX 1 0.18 0.14 0.4
32 INT236110 Binding of Ppara and Olfm4 1 0.00 1.22 0.4
33 INT236111 Binding of Pdpk1 and Ppara 1 0.26 1.21 0.39
34 INT297423 Gene_expression of Il4 Regulation of Ppara 1 0.07 1.19 0.38
35 INT297424 Gene_expression of Stat6 Regulation of Ppara 1 0.17 1.19 0.38
36 INT297425 Il4 Regulation of Ppara 1 0.07 1.17 0.38
37 INT297426 Stat6 Regulation of Ppara 1 0.17 1.19 0.38
38 INT235432 Ppara Negative_regulation of Gene_expression of Cpox 1 0.01 1 0.37
39 INT221814 Mastl Positive_regulation of Ppara 1 0.04 0.68 0.37
40 INT297352 KLF2 Regulation of PPARA 1 0.12 1.31 0.35
41 INT204071 HP Positive_regulation of Gene_expression of CDKN2A 1 0.00 3.48 0.34
42 INT301665 CYP2C9 Regulation of Binding of Ppara 1 0.26 1.79 0.34
43 INT130803 MC1R Regulation of Positive_regulation of Cdkn2a 1 0.17 0.82 0.34
44 INT333457 Binding of PPARA and TGFB1 1 0.04 0 0.34
45 INT297351 EWSR1 Positive_regulation of PPARA 1 0.41 1.81 0.33
46 INT240434 PPARA Negative_regulation of Gene_expression of CPOX 1 0.03 0.64 0.33
47 INT91814 Binding of TNF and TP53 1 0.14 2.2 0.32
48 INT215395 Csf2 Positive_regulation of Ppara 1 0.12 1.33 0.32
49 INT166394 CDKN1B Regulation of Gene_expression of TP53 1 0.28 0.41 0.31
50 INT148556 PPARG Regulation of Gene_expression of PPARA 1 0.30 1.2 0.31
51 INT166396 IFI27 Regulation of Gene_expression of TP53 1 0.19 0.41 0.31
52 INT332972 Fas Positive_regulation of Ppara 1 0.17 0.52 0.31
53 INT187603 Binding of Ptgis and Ppara 1 0.00 0.26 0.31
54 INT333453 Binding of PPARA and RXRA 1 0.02 0 0.31
55 INT209931 IL1B Positive_regulation of PPARA 1 0.32 0.62 0.31
56 INT307215 Negative_regulation of Prkca Negative_regulation of Ppara 1 0.09 0.21 0.3
57 INT333917 MDM2 Positive_regulation of Protein_catabolism of Trp53 1 0.01 1.23 0.3
58 INT333918 HDAC1 Regulation of Trp53 1 0.03 1.24 0.3
59 INT163761 MDM2 Positive_regulation of Gene_expression of TP53 1 0.40 0.86 0.3
60 INT209933 PPARA Regulation of Positive_regulation of IL1B 1 0.21 0.58 0.29
61 INT299956 Binding of PPARA and EPC1 1 0.09 0.34 0.29
62 INT166952 LYRM4 Positive_regulation of Gene_expression of TP53 1 0.05 0.75 0.28
63 INT335134 PPARA Negative_regulation of Cyp1a1 1 0.47 0 0.28
64 INT344704 Positive_regulation of Ppara Positive_regulation of Binding of Hdl1 1 0.13 0.83 0.28
65 INT286042 Binding of Tp53 and Wwox 1 0.04 2.05 0.28
66 INT216127 EGR1 Regulation of Transcription of TP53 1 0.06 0.21 0.28
67 INT159201 Binding of Ppard and Ppara 1 0.01 0.68 0.28
68 INT302837 Binding of TNFRSF10D and Trp53 1 0.01 0.98 0.28
69 INT344715 Positive_regulation of Ppara Positive_regulation of Gene_expression of Pltp 1 0.02 0.83 0.28
70 INT172901 Binding of Bad and Bcl2l1 3 0.13 6.51 0.27
71 INT101510 PPARA Regulation of IL6 1 0.31 0.53 0.27
72 INT306267 Binding of INCENP and TP53 1 0.02 0.83 0.27
73 INT101508 PPARA Regulation of IL8 1 0.31 0.53 0.27
74 INT216128 EGR1 Regulation of TP53 1 0.11 0.21 0.27
75 INT101509 PPARA Regulation of Gene_expression of IL8 1 0.31 0.53 0.27
76 INT101511 PPARA Regulation of Gene_expression of IL6 1 0.31 0.53 0.27
77 INT335130 PPARA Positive_regulation of Cyp8b1 1 0.37 0 0.27
78 INT352931 Prkaca Regulation of TP53 1 0.13 1.01 0.26
79 INT203733 Thbs1 Positive_regulation of Negative_regulation of Ppara 1 0.36 1.55 0.26
80 INT352930 Prkaca Regulation of Phosphorylation of TP53 1 0.13 1.02 0.26
81 INT182325 TP53 Negative_regulation of Transcription of Birc5 1 0.01 1.34 0.26
82 INT335049 PPARA Negative_regulation of Gene_expression of CYP7B1 1 0.27 0 0.26
83 INT147593 Binding of CDK4 and CDKN2A 1 0.42 0.23 0.26
84 INT172975 Trp53 Positive_regulation of Cdkn1a 1 0.03 1.35 0.26
85 INT239335 Eef1a2 Positive_regulation of Ppara 1 0.27 0.57 0.26
86 INT245072 PPARA Regulation of Gene_expression of CXCR4 1 0.07 0.68 0.26
87 INT147592 Positive_regulation of Binding of CDK4 and CDKN2A 1 0.44 0.23 0.26
88 INT352893 PTGDS Regulation of TP53 1 0.16 1.02 0.26
89 INT125516 TP53 Regulation of GDF15 1 0.10 0.47 0.26
90 INT337086 Mif Negative_regulation of Localization of Trp53 1 0.16 1.64 0.25
91 INT335126 Ptgs2 Positive_regulation of Gene_expression of PPARA 1 0.24 0.72 0.25
92 INT35178 Binding of STT3A and PSME3 1 0.01 0.38 0.25
93 INT337091 Mif Negative_regulation of Positive_regulation of Trp53 1 0.16 1.64 0.25
94 INT307207 Ppara Positive_regulation of Apoa2 1 0.10 0.94 0.25
95 INT156879 Gene_expression of TP53 Negative_regulation of Positive_regulation of PDF 1 0.45 0.9 0.24
96 INT181900 TP53 Negative_regulation of Gene_expression of NOS1 1 0.03 0.94 0.24
97 INT254773 PPARA Positive_regulation of Gene_expression of Apoe 1 0.01 0.07 0.24
98 INT156881 TP53 Positive_regulation of Positive_regulation of PDF 1 0.49 0.89 0.24
99 INT173120 Binding of PPARA and NR1H4 8 0.09 2.79 0.23
100 INT298785 PPARA Positive_regulation of ACOX1 3 0.29 1.58 0.23
101 INT238383 Tlr4 Positive_regulation of Ppara 1 0.17 0.41 0.23
102 INT215396 Il4 Positive_regulation of Gene_expression of Ppara 1 0.03 0.23 0.23
103 INT229177 IFRD1 Regulation of TP53 1 0.13 0.68 0.23
104 INT229702 Binding of Ppara and Ros1 1 0.01 1.05 0.23
105 INT226902 Padi3 Regulation of Trp53 1 0.06 0.69 0.22
106 INT233929 PPARA Negative_regulation of ras 1 0.02 2.39 0.22
107 INT229178 TP53 Regulation of ICAM1 1 0.07 0.9 0.21
108 INT263339 Ptger2 Regulation of Ppara 1 0.09 0.44 0.21
109 INT156882 Binding of TP53 and PDF 1 0.39 0.77 0.21
110 INT156880 TP53 Positive_regulation of Gene_expression of PDF 1 0.49 0.75 0.21
111 INT210887 Sst Positive_regulation of Gene_expression of Trp53 1 0.33 0.93 0.2
112 INT109409 PPARA Positive_regulation of Gene_expression of SAT1 1 0.54 0.75 0.2
113 INT209850 IL4 Positive_regulation of Gene_expression of PPARA 1 0.18 0.23 0.19
114 INT298787 Binding of PPARA and TUSC5 1 0.32 1.38 0.19
115 INT298784 PPARA Positive_regulation of CPT1B 1 0.28 1.61 0.19
116 INT335053 PPARA Positive_regulation of Gene_expression of LPL 1 0.21 0.34 0.19
117 INT193787 Positive_regulation of CXCR4 Positive_regulation of Positive_regulation of TP53 1 0.03 0.71 0.19
118 INT142853 Binding of TP53 and WISP2 1 0.33 1.43 0.19
119 INT220513 Ugt1a6b Positive_regulation of Ppara 1 0.01 0.98 0.18
120 INT242993 Positive_regulation of Ppara Positive_regulation of Gene_expression of Spp1 1 0.24 0.66 0.18
121 INT335046 PPARA Positive_regulation of Gene_expression of ABCA1 1 0.33 0.25 0.18
122 INT312519 DAK Positive_regulation of PPARA 1 0.00 1.46 0.18
123 INT220524 Ppara Negative_regulation of Positive_regulation of Gdf15 1 0.01 0.56 0.17
124 INT220516 Ppara Negative_regulation of Positive_regulation of Atf3 1 0.10 0.56 0.17
125 INT302295 PPARA Regulation of OAS2 1 0.01 0.72 0.17
126 INT335131 PPARA Negative_regulation of Gene_expression of Fgg 1 0.01 0.59 0.17
127 INT102804 NFKB1 Regulation of TP53 1 0.35 0.77 0.17
128 INT278609 PPARA Positive_regulation of Gene_expression of SULT2A1 1 0.33 0 0.17
129 INT102803 NFKB1 Regulation of Gene_expression of TP53 1 0.35 0.77 0.17
130 INT298641 PPARA Regulation of STAT3 1 0.23 0.98 0.16
131 INT235441 HMBS Regulation of PPARA 1 0.03 0.76 0.16
132 INT91812 Binding of FASLG and TP53 1 0.04 1.1 0.16
133 INT290670 Binding of Nos2 and Ppara 1 0.17 0.41 0.16
134 INT91811 Binding of FAS and TP53 1 0.21 1.1 0.16
135 INT332968 Hoxb4 Positive_regulation of Ppara 1 0.02 0.25 0.16
136 INT136855 Arf5 Positive_regulation of Cdkn2a 1 0.07 1.8 0.15
137 INT266377 Binding of S100a11 and Trp53 1 0.02 0.89 0.15
138 INT298782 PPARA Positive_regulation of Gene_expression of TUSC5 1 0.42 0.62 0.15
139 INT314856 Binding of Cdc7 and Cdkn2a 1 0.28 1.34 0.14
140 INT302146 CDKN2A Regulation of CDKN1B 1 0.11 0.51 0.14
141 INT311666 Binding of BCL2 and TP53 1 0.19 1.26 0.14
142 INT302144 CDKN2A Regulation of CDKN1A 1 0.11 0.51 0.14
143 INT170585 PPARA Negative_regulation of DYM 1 0.03 0.07 0.14
144 INT225608 Ppara Regulation of Ncoa6 1 0.27 0.44 0.14
145 INT301638 Ppara Regulation of Slc27a2 1 0.30 0.29 0.14
146 INT314852 Binding of Cdkn2a and Tgfbr3 1 0.28 1.15 0.14
147 INT215394 Binding of Csf2 and Positive_regulation of Ppara 1 0.12 0.49 0.14
148 INT265956 Clas4 Regulation of PPARA 1 0.01 0.7 0.14
149 INT329847 PPARA Regulation of Gene_expression of CREB3L3 1 0.17 0.84 0.13
150 INT103557 Binding of ERCC2 and TP53 1 0.40 1 0.13
151 INT332966 Binding of Fas and Ppara 1 0.15 0.25 0.13
152 INT145058 Nr1i3 Regulation of Transcription of Ppara 1 0.28 0.23 0.13
153 INT132148 LTF Positive_regulation of TP53 1 0.44 0.56 0.13
154 INT333396 CFD Positive_regulation of Bcl2l1 1 0.05 0.98 0.13
155 INT103561 Binding of TP53 and Mc1r 1 0.03 1 0.13
156 INT342311 Binding of Tp53 and Positive_regulation of Gene_expression of BCL2 1 0.08 1.25 0.13
157 INT227556 Ptgds Positive_regulation of Ppara 1 0.18 0.62 0.13
158 INT172899 Binding of Bcl2 and Bcl2l1 3 0.02 5.54 0.12
159 INT173121 PPARA Negative_regulation of Gene_expression of CYP7A1 1 0.18 0.48 0.12
160 INT83370 Binding of HRAS and TP53 1 0.30 0.59 0.11
161 INT278607 SULT2A1 Positive_regulation of Binding of PPARA 1 0.24 0 0.11
162 INT298828 Binding of PPARA and Lpl 1 0.05 0.77 0.11
163 INT332893 Ppara Regulation of Gene_expression of Arntl 1 0.43 0 0.11
164 INT342227 TRNAI1 Positive_regulation of Ppara 1 0.03 1.06 0.11
165 INT266386 Binding of S100a1 and Trp53 1 0.03 0.64 0.1
166 INT202619 Binding of Ppara and Spna1 1 0.01 0.27 0.1
167 INT173126 CYP8B1 Positive_regulation of PPARA 1 0.25 0.39 0.1
168 INT193782 Binding of TP53 and SDF2L1 1 0.00 0.67 0.1
169 INT332891 Per2 Positive_regulation of Ppara 1 0.43 0 0.1
170 INT262522 Binding of Trp53 and Foxo4 1 0.05 0.7 0.1
171 INT310743 TP53 Regulation of BAX 1 0.09 1.11 0.1
172 INT157265 PPARG Positive_regulation of PPARA 1 0.22 1.15 0.09
173 INT157266 PPARA Positive_regulation of ADIPOR1 1 0.00 1.19 0.09
174 INT301660 Ppara Regulation of Gene_expression of CYP4A11 1 0.24 0.65 0.09
175 INT298783 PPARA Positive_regulation of TUSC5 1 0.37 0.15 0.09
176 INT326126 Binding of S100A1 and TP53 1 0.04 1.34 0.09
177 INT290673 Ppara Positive_regulation of Gtf3a 1 0.01 0.58 0.09
178 INT275184 Bad Positive_regulation of Positive_regulation of Bcl2l1 1 0.12 0.62 0.09
179 INT298786 PPARA Positive_regulation of Transcription of CPT1B 1 0.17 0.93 0.09
180 INT298781 Positive_regulation of PPARA Positive_regulation of TUSC5 1 0.37 0.15 0.09
181 INT323071 Binding of RT1-DOa and Ppara 1 0.13 0.74 0.09
182 INT301663 Ppara Regulation of CYP4A11 1 0.14 0.65 0.09
183 INT352611 Trp53 Negative_regulation of Localization of Gli1 1 0.23 1.2 0.09
184 INT302168 YWHAQ Regulation of TP53 1 0.01 0.41 0.09
185 INT265466 CSPG4 Regulation of Phosphorylation of TP53 1 0.09 0.15 0.09
186 INT234437 asa Negative_regulation of Ppara 1 0.13 0.4 0.09
187 INT173130 Binding of INS and PPARA 2 0.04 1.8 0.08
188 INT246625 Sirt1 Positive_regulation of Negative_regulation of Trp53 1 0.10 0.96 0.08
189 INT186729 Csf2 Positive_regulation of PPARA 1 0.06 1.04 0.08
190 INT302178 CDKN1C Regulation of CDKN2A 1 0.09 0.26 0.08
191 INT335051 PPARA Positive_regulation of PCTP 1 0.10 0.38 0.08
192 INT157264 PPARA Positive_regulation of PRKAA1 1 0.03 0.92 0.08
193 INT302158 CDKN1A Regulation of CDKN2A 1 0.04 0.26 0.08
194 INT157263 PPARA Positive_regulation of APRT 1 0.54 0.92 0.08
195 INT279419 RARB Regulation of PPARA 1 0.01 0.13 0.08
196 INT136856 Cdkn2a Positive_regulation of Arf5 1 0.01 0.9 0.08
197 INT279416 NR1H4 Regulation of PPARA 1 0.01 0.13 0.08
198 INT229703 Binding of Ppara and Rxrg 1 0.03 0.08 0.08
199 INT186712 INCENP Positive_regulation of PPARA 1 0.01 1.05 0.08
200 INT157270 PPARA Positive_regulation of Adipor2 1 0.05 0.92 0.08

Single Events

The table below shows the top 100 pain related interactions that have been reported for MDM2 binding. They are ordered first by their pain relevance and then by number of times they were reported in MDM2 binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36
2 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14
3 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45
4 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61
5 INT122041 Binding of Ppara 308 0.48 189.17 51.48
6 INT103094 Binding of PPARA 308 0.47 177.26 34.75
7 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
8 INT122039 Positive_regulation of Gene_expression of Ppara 144 0.68 113.55 28.55
9 INT115385 Negative_regulation of Ppara 154 0.58 129.05 27.58
10 INT83797 Gene_expression of Bcl2l1 124 0.77 94.55 22.39
11 INT61116 Positive_regulation of Ppara 119 0.69 58.62 21.6
12 INT101517 Negative_regulation of PPARA 168 0.57 112.24 21.41
13 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71
14 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
15 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
16 INT61117 Gene_expression of Ppara 158 0.68 69.3 15.98
17 INT103096 Regulation of PPARA 113 0.60 62.47 14.57
18 INT100139 Positive_regulation of Gene_expression of PPARA 160 0.63 97.78 14.53
19 INT94774 Regulation of CDKN2A 43 0.60 44.41 13.99
20 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61
21 INT122037 Regulation of Ppara 93 0.62 56.28 12.89
22 INT194462 Localization of Ppara 94 0.78 68.33 12.09
23 INT173159 Localization of PPARA 96 0.74 64.55 10.26
24 INT99505 Gene_expression of Bcl2l1 42 0.77 33.12 10.15
25 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
26 INT122584 Negative_regulation of Gene_expression of PPARA 56 0.58 37.61 9.76
27 INT181817 Negative_regulation of Gene_expression of Ppara 58 0.58 43.24 7.67
28 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49
29 INT92138 Binding of CDKN2A 28 0.37 25.64 7.47
30 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25
31 INT138799 Regulation of Gene_expression of Ppara 40 0.60 29.42 6.89
32 INT170922 Binding of Ppara 59 0.45 28.45 6.7
33 INT194479 Phosphorylation of Ppara 47 0.81 30.36 6.6
34 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24
35 INT99506 Negative_regulation of Bcl2l1 25 0.58 15.7 6.09
36 INT181194 Regulation of Gene_expression of PPARA 31 0.44 21.27 5.96
37 INT112545 Phosphorylation of TP53 28 0.80 14.13 5.93
38 INT86025 Positive_regulation of Positive_regulation of PPARA 34 0.52 22.89 5.74
39 INT86023 Transcription of PPARA 60 0.66 25.8 5.7
40 INT125467 Positive_regulation of Gene_expression of CDKN2A 35 0.63 39.07 5.56
41 INT91147 Positive_regulation of Positive_regulation of Ppara 30 0.69 19.31 5.56
42 INT13295 Positive_regulation of Cdkn2a 18 0.68 13.02 5.47
43 INT89794 Positive_regulation of CDKN2A 58 0.67 50.18 5.38
44 INT60585 Regulation of TP53 59 0.59 54.55 5.21
45 INT122038 Transcription of Ppara 35 0.71 20.5 5.12
46 INT170927 Negative_regulation of Ppara 27 0.54 13.58 5.12
47 INT99507 Positive_regulation of Bcl2l1 17 0.69 9.23 4.97
48 INT109972 Phosphorylation of Trp53 13 0.80 6.15 4.68
49 INT116614 Positive_regulation of Gene_expression of Bcl2l1 12 0.67 11.39 4.68
50 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62
51 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45
52 INT197171 Negative_regulation of Binding of Ppara 15 0.43 11.51 4.41
53 INT83794 Positive_regulation of Gene_expression of Bcl2l1 26 0.69 16.89 4.28
54 INT83798 Negative_regulation of Gene_expression of Bcl2l1 28 0.58 20.26 4.21
55 INT83796 Regulation of Gene_expression of Bcl2l1 10 0.61 7.85 4.05
56 INT95423 Negative_regulation of Bcl2l1 26 0.41 21.66 3.81
57 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68
58 INT114957 Positive_regulation of Transcription of PPARA 18 0.62 10.36 3.65
59 INT78471 Regulation of Gene_expression of CDKN2A 13 0.45 12.52 3.28
60 INT147522 Positive_regulation of Gene_expression of Ppara 28 0.47 15.82 3.18
61 INT86245 Positive_regulation of Bcl2l1 15 0.46 12.67 3.11
62 INT187618 Localization of Ppara 13 0.70 6.91 3.09
63 INT82913 Regulation of Ppara 15 0.61 10.66 3.03
64 INT8103 Binding of TP53 46 0.44 40.2 2.96
65 INT78248 Negative_regulation of Cdkn2a 17 0.59 15.15 2.8
66 INT222961 Negative_regulation of Binding of PPARA 22 0.41 10.76 2.72
67 INT99508 Regulation of Bcl2l1 12 0.61 10.44 2.71
68 INT100144 Negative_regulation of Positive_regulation of PPARA 17 0.49 12.71 2.68
69 INT109969 Positive_regulation of Phosphorylation of Trp53 1 0.45 2.18 2.66
70 INT112962 Regulation of Positive_regulation of Ppara 17 0.45 10.63 2.58
71 INT147517 Negative_regulation of Gene_expression of Ppara 12 0.37 3.46 2.55
72 INT109968 Positive_regulation of Positive_regulation of Trp53 6 0.47 3.57 2.51
73 INT92141 Negative_regulation of CDKN2A 53 0.57 44.23 2.48
74 INT338170 Regulation of Regulation of CDKN2A 1 0.44 0.96 2.46
75 INT55952 Transcription of TP53 16 0.61 12.14 2.36
76 INT215379 Positive_regulation of Binding of Ppara 15 0.66 8.04 2.36
77 INT83799 Phosphorylation of Bcl2l1 8 0.82 7.86 2.23
78 INT215378 Protein_catabolism of Ppara 12 0.86 5.12 2.14
79 INT101645 Regulation of Gene_expression of Bcl2l1 8 0.36 5.27 2.05
80 INT94772 Gene_expression of Cdkn2a 14 0.75 8.25 2.04
81 INT125080 Positive_regulation of Positive_regulation of TP53 21 0.58 16.16 1.98
82 INT146793 Positive_regulation of Tp53 30 0.70 32.93 1.94
83 INT65855 Localization of TP53 18 0.76 17.08 1.89
84 INT173180 Positive_regulation of Binding of PPARA 14 0.49 3.66 1.88
85 INT211984 Regulation of Binding of Ppara 11 0.45 9.55 1.87
86 INT168269 Negative_regulation of Positive_regulation of Ppara 3 0.38 0.57 1.87
87 INT113345 Positive_regulation of Phosphorylation of TP53 8 0.66 6.11 1.8
88 INT173177 Positive_regulation of Localization of PPARA 21 0.49 12.61 1.74
89 INT64233 Regulation of Trp53 35 0.62 27.11 1.53
90 INT106413 Transcription of Bcl2l1 8 0.53 3.35 1.52
91 INT120004 Transcription of Tp53 8 0.72 4.92 1.48
92 INT173198 Regulation of Binding of PPARA 17 0.43 9.58 1.47
93 INT112963 Regulation of Positive_regulation of PPARA 8 0.44 5.29 1.43
94 INT101990 Negative_regulation of Positive_regulation of TP53 5 0.33 3.69 1.42
95 INT162469 Positive_regulation of Protein_catabolism of TP53 5 0.52 5.48 1.42
96 INT172953 Binding of Trp53 33 0.37 20.76 1.41
97 INT93357 Regulation of Gene_expression of Trp53 15 0.62 13.4 1.41
98 INT162462 Protein_catabolism of TP53 8 0.86 7.89 1.41
99 INT173162 Phosphorylation of PPARA 22 0.80 11.09 1.38
100 INT78470 Negative_regulation of Gene_expression of CDKN2A 14 0.59 14.44 1.38
101 INT145221 Binding of Tp53 10 0.37 8.59 1.37
102 INT122040 Positive_regulation of Transcription of Ppara 9 0.50 3.97 1.33
103 INT105881 Phosphorylation of Bcl2l1 3 0.51 1.99 1.31
104 INT197167 Positive_regulation of Localization of Ppara 18 0.67 9.51 1.21
105 INT183635 Negative_regulation of Positive_regulation of Ppara 11 0.42 10 1.2
106 INT174156 Localization of Trp53 16 0.72 13.52 1.18
107 INT227548 Negative_regulation of Localization of Ppara 7 0.38 4.1 1.17
108 INT116436 Negative_regulation of Phosphorylation of TP53 2 0.40 0.94 1.16
109 INT134661 Negative_regulation of Tp53 11 0.43 10.91 1.13
110 INT42104 Regulation of Cdkn2a 4 0.44 5.67 1.06
111 INT135806 Regulation of Bcl2l1 10 0.44 7.21 1.05
112 INT97052 Transcription of Trp53 12 0.64 6.52 1.01
113 INT188513 Negative_regulation of Binding of Ppara 2 0.35 2.02 1.01
114 INT164863 Positive_regulation of Phosphorylation of Bcl2l1 1 0.31 0.57 1.01
115 INT147518 Regulation of Gene_expression of Ppara 7 0.42 4.59 0.97
116 INT338168 Positive_regulation of Binding of CDKN2A 1 0.49 0.52 0.94
117 INT227552 Regulation of Phosphorylation of Ppara 7 0.44 3.13 0.92
118 INT236104 Positive_regulation of Negative_regulation of Ppara 6 0.59 6.91 0.91
119 INT190361 Protein_catabolism of PPARA 12 0.97 3.01 0.87
120 INT190363 Positive_regulation of Negative_regulation of PPARA 10 0.44 4.8 0.87
121 INT161754 Transcription of Ppara 10 0.52 4.06 0.84
122 INT93356 Negative_regulation of Gene_expression of Trp53 28 0.53 20.61 0.8
123 INT236707 Regulation of Negative_regulation of Ppara 5 0.41 2.97 0.8
124 INT144429 Positive_regulation of Cdkn2a 7 0.58 4.05 0.78
125 INT187619 Positive_regulation of Binding of Ppara 6 0.65 3.17 0.78
126 INT238442 Regulation of Transcription of PPARA 3 0.37 2.64 0.77
127 INT129115 Negative_regulation of Cdkn2a 16 0.50 17.03 0.76
128 INT102813 Regulation of Gene_expression of TP53 25 0.59 25.95 0.75
129 INT168245 Positive_regulation of Transcription of Tp53 2 0.70 2.63 0.75
130 INT162470 Negative_regulation of Protein_catabolism of TP53 1 0.32 1.24 0.74
131 INT131567 Negative_regulation of Positive_regulation of Bcl2l1 1 0.41 0.66 0.7
132 INT186727 Negative_regulation of Localization of PPARA 4 0.35 4.56 0.69
133 INT209935 Regulation of Regulation of PPARA 4 0.44 1.56 0.69
134 INT131568 Positive_regulation of Positive_regulation of Bcl2l1 1 0.48 0.64 0.68
135 INT251026 Negative_regulation of Phosphorylation of CDKN2A 5 0.42 5.02 0.62
136 INT177886 Positive_regulation of Gene_expression of Cdkn2a 3 0.67 3.42 0.62
137 INT187620 Positive_regulation of Positive_regulation of Ppara 4 0.44 2.05 0.61
138 INT188714 Regulation of Negative_regulation of PPARA 2 0.32 1.44 0.61
139 INT93358 Negative_regulation of Positive_regulation of Trp53 9 0.41 3.95 0.6
140 INT53950 Phosphorylation of Tp53 8 0.61 9.4 0.6
141 INT147598 Negative_regulation of Positive_regulation of CDKN2A 3 0.41 1.47 0.59
142 INT86246 Binding of Bcl2l1 8 0.37 6.67 0.57
143 INT152057 Negative_regulation of Transcription of Bcl2l1 3 0.43 1 0.55
144 INT188500 Regulation of Positive_regulation of Ppara 3 0.39 1.19 0.55
145 INT242011 Localization of Cdkn2a 4 0.73 2.49 0.54
146 INT144701 Gene_expression of Cdkn2a 15 0.75 8.42 0.53
147 INT228579 Protein_catabolism of Ppara 2 0.55 2.8 0.53
148 INT144431 Positive_regulation of Transcription of Cdkn2a 1 0.41 1.11 0.51
149 INT144426 Transcription of Cdkn2a 1 0.42 1.11 0.51
150 INT152058 Regulation of Transcription of Bcl2l1 2 0.32 0.53 0.5
151 INT180458 Regulation of Regulation of Ppara 6 0.45 6.44 0.49
152 INT286035 Negative_regulation of Gene_expression of Tp53 5 0.32 6.2 0.49
153 INT231731 Positive_regulation of Protein_catabolism of Ppara 1 0.30 2.28 0.48
154 INT165799 Negative_regulation of Gene_expression of Bcl2l1 6 0.41 5.12 0.47
155 INT106415 Positive_regulation of Transcription of Bcl2l1 1 0.20 0.49 0.46
156 INT152056 Negative_regulation of Regulation of Bcl2l1 1 0.58 0.07 0.45
157 INT220088 Positive_regulation of Positive_regulation of CDKN2A 4 0.49 4.04 0.44
158 INT187615 Regulation of Binding of Ppara 3 0.15 2.09 0.43
159 INT190362 Negative_regulation of Transcription of PPARA 5 0.42 3.19 0.42
160 INT252657 Positive_regulation of Phosphorylation of CDKN2A 2 0.45 3.09 0.42
161 INT42105 Regulation of Positive_regulation of Cdkn2a 1 0.44 0.33 0.42
162 INT197168 Regulation of Localization of Ppara 6 0.39 3.7 0.41
163 INT139976 Regulation of Tp53 7 0.44 6.49 0.39
164 INT194468 Positive_regulation of Phosphorylation of Ppara 4 0.46 2.11 0.38
165 INT188715 Negative_regulation of Negative_regulation of PPARA 3 0.37 1.25 0.37
166 INT239779 Negative_regulation of Regulation of Ppara 4 0.42 1.48 0.36
167 INT145220 Negative_regulation of Binding of Tp53 1 0.20 0.75 0.36
168 INT105885 Binding of Bcl2l1 2 0.05 1.13 0.35
169 INT215377 Negative_regulation of Protein_catabolism of Ppara 2 0.31 0.5 0.35
170 INT196323 Localization of Cdkn2a 8 0.73 9.1 0.32
171 INT251025 Phosphorylation of CDKN2A 4 0.61 3.19 0.32
172 INT145051 Regulation of Transcription of Ppara 5 0.43 2.14 0.31
173 INT93355 Negative_regulation of Negative_regulation of Trp53 2 0.41 0.92 0.3
174 INT179089 Protein_catabolism of Trp53 8 0.90 6.52 0.29
175 INT228477 Positive_regulation of Gene_expression of Cdkn2a 2 0.11 1.3 0.29
176 INT187607 Phosphorylation of Ppara 3 0.66 0.57 0.28
177 INT149998 Positive_regulation of Positive_regulation of Bcl2l1 1 0.05 1.73 0.28
178 INT188511 Positive_regulation of Transcription of Ppara 2 0.22 0.22 0.26
179 INT166960 Positive_regulation of Negative_regulation of TP53 2 0.25 1.65 0.26
180 INT184624 Localization of CDKN2A 8 0.74 7.87 0.25
181 INT314729 Regulation of Localization of TP53 1 0.30 2.5 0.25
182 INT238494 Regulation of Transcription of CDKN2A 1 0.16 5.62 0.25
183 INT179088 Positive_regulation of Regulation of Trp53 3 0.38 3.23 0.23
184 INT156886 Positive_regulation of Localization of TP53 1 0.48 0.87 0.23
185 INT301573 Positive_regulation of Protein_catabolism of Ppara 1 0.37 0.28 0.22
186 INT209076 Negative_regulation of PSME3 2 0.34 0.86 0.21
187 INT227671 Protein_catabolism of Bcl2l1 2 0.18 0.96 0.19
188 INT356122 Regulation of Phosphorylation of Bcl2l1 1 0.09 0.69 0.19
189 INT209077 Positive_regulation of Negative_regulation of PSME3 1 0.37 0.13 0.19
190 INT161752 Regulation of Transcription of Ppara 1 0.03 0.94 0.19
191 INT241687 Binding of Cdkn2a 5 0.31 5.26 0.18
192 INT300284 Regulation of Phosphorylation of Tp53 1 0.16 1.51 0.17
193 INT337078 Negative_regulation of Localization of Trp53 1 0.20 1.3 0.17
194 INT234411 Negative_regulation of Phosphorylation of PPARA 2 0.36 0.29 0.16
195 INT147149 Transcription of CDKN2A 8 0.67 6.85 0.15
196 INT179086 Positive_regulation of Negative_regulation of Trp53 5 0.50 4.78 0.15
197 INT125081 Positive_regulation of Binding of TP53 2 0.46 1.2 0.15
198 INT207805 Negative_regulation of Phosphorylation of Trp53 2 0.18 0.98 0.15
199 INT286749 Regulation of Localization of Trp53 1 0.06 1.39 0.15
200 INT225216 Negative_regulation of Negative_regulation of Cdkn2a 1 0.42 3.16 0.15
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