GO:0070290

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Name NAPE-specific phospholipase D activity
Categary Function
Go Slim No
Go Link GO:0070290
Unique Molecular Interactions 30
Total Molecular Interactions 53
Total Single Events 264
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for NAPE-specific phospholipase D activity. They are ordered first by their pain relevance and then by number of times they were reported for NAPE-specific phospholipase D activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT134284 Binding of OPRM1 and PLD2 1 0.52 0 3.72
2 INT107738 Binding of Pld2 and Oprm1 1 0.23 0 1.93
3 INT162165 WDTC1 Positive_regulation of PLD2 1 0.50 0 1.25
4 INT162163 CDKN2A Positive_regulation of PLD2 1 0.24 0 1.24
5 INT107739 Prkcg Negative_regulation of Positive_regulation of Pld2 1 0.46 0 0.79
6 INT162164 ARF6 Regulation of Positive_regulation of PLD2 1 0.60 0 0.74
7 INT107741 Binding of OPRM1 and Pld2 1 0.01 0 0.69
8 INT134286 PLD2 Regulation of Regulation of EDNRA 1 0.10 0 0.67
9 INT134287 PLD2 Regulation of Regulation of MRGPRX1 1 0.31 0 0.67
10 INT160880 Pld2 Positive_regulation of Oprm1 1 0.07 0.08 0.63
11 INT160882 Pld2 Positive_regulation of Gene_expression of Oprm1 1 0.06 0.08 0.63
12 INT308803 Binding of Pld1 and Pld2 1 0.13 1.11 0.59
13 INT160881 Positive_regulation of Oprm1 Positive_regulation of Positive_regulation of Pld2 1 0.05 0.08 0.48
14 INT156518 Binding of FAAH and NAPEPLD 1 0.38 0.19 0.46
15 INT73831 Binding of Mc1r and Pld1 1 0.00 0.16 0.45
16 INT73832 Pld1 Positive_regulation of ADCY1 1 0.00 0.16 0.44
17 INT156520 Binding of CNR2 and NAPEPLD 1 0.39 0.19 0.4
18 INT156519 Binding of CNR1 and NAPEPLD 1 0.39 0.19 0.4
19 INT83271 Gda Negative_regulation of Napepld 1 0.05 0 0.1
20 INT83270 Snca Regulation of Napepld 1 0.14 0 0.09
21 INT169794 Binding of Pld1 and Aia1 1 0.00 0 0
22 INT326898 Positive_regulation of Tcf4 Regulation of PLD2 1 0.26 0.33 0
23 INT326899 Tcf4 Positive_regulation of PLD2 1 0.28 0.49 0
24 INT326836 Binding of HNF4A and PLD2 1 0.03 0.35 0
25 INT326895 Binding of PLD2 and Tcf4 1 0.27 0.39 0
26 INT326900 Tcf4 Regulation of PLD2 1 0.15 0.33 0
27 INT326896 Wnt3a Positive_regulation of Transcription of PLD2 1 0.24 0.06 0
28 INT343082 Binding of Prm3 and Pld4 1 0.05 0 0
29 INT326901 Binding of PLD2 and Pld1 1 0.28 0.46 0
30 INT326897 Tcf4 Positive_regulation of Gene_expression of PLD2 1 0.26 0.41 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for NAPE-specific phospholipase D activity. They are ordered first by their pain relevance and then by number of times they were reported in NAPE-specific phospholipase D activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT107737 Positive_regulation of Pld2 11 0.67 0.33 6.45
2 INT134290 Positive_regulation of PLD2 10 0.68 3.06 6.44
3 INT115805 Gene_expression of PLD2 7 0.76 12.49 4.51
4 INT107113 Gene_expression of Pld1 6 0.78 2.71 4.28
5 INT115806 Positive_regulation of Gene_expression of PLD2 5 0.57 7.12 3.11
6 INT156522 Gene_expression of NAPEPLD 11 0.75 4.25 2.87
7 INT107735 Positive_regulation of Positive_regulation of Pld2 3 0.48 0 1.47
8 INT115807 Negative_regulation of PLD2 3 0.57 0.69 1.43
9 INT107732 Gene_expression of Pld2 1 0.75 0 1.25
10 INT162169 Negative_regulation of Positive_regulation of PLD2 1 0.56 0 0.92
11 INT280218 Negative_regulation of Gene_expression of NAPEPLD 1 0.33 1.1 0.76
12 INT162170 Regulation of Positive_regulation of PLD2 1 0.26 0 0.74
13 INT107736 Positive_regulation of Gene_expression of Pld2 1 0.67 0 0.74
14 INT107114 Positive_regulation of Gene_expression of Pld1 1 0.70 0.45 0.67
15 INT107112 Regulation of Pld1 1 0.27 0.44 0.65
16 INT134289 Positive_regulation of Positive_regulation of PLD2 2 0.46 0 0.6
17 INT308802 Binding of Pld2 1 0.13 1.11 0.59
18 INT115803 Regulation of PLD2 1 0.44 0.43 0.53
19 INT145467 Positive_regulation of Napepld 1 0.38 0 0.51
20 INT145466 Regulation of Napepld 1 0.25 0 0.47
21 INT161692 Regulation of NAPEPLD 2 0.17 0.9 0.45
22 INT280228 Regulation of Gene_expression of NAPEPLD 1 0.26 1.04 0.42
23 INT161693 Localization of NAPEPLD 3 0.44 0.1 0.37
24 INT308793 Gene_expression of Pld2 9 0.32 0.51 0.27
25 INT343068 Gene_expression of Pld4 1 0.61 0.27 0.25
26 INT140390 Binding of Pld1 1 0.00 0.1 0.23
27 INT83267 Gene_expression of Napepld 1 0.67 0 0.19
28 INT206656 Phosphorylation of NAPEPLD 1 0.08 0.99 0.16
29 INT343069 Transcription of Pld4 1 0.56 0.23 0.16
30 INT206658 Negative_regulation of NAPEPLD 2 0.04 2.18 0.1
31 INT83269 Negative_regulation of Napepld 1 0.43 0 0.1
32 INT206657 Positive_regulation of NAPEPLD 4 0.07 1.05 0.05
33 INT308794 Positive_regulation of Gene_expression of Pld2 2 0.17 0.07 0.04
34 INT326879 Binding of PLD2 1 0.31 2.21 0.04
35 INT343064 Localization of Pld4 1 0.59 0 0.03
36 INT206655 Binding of NAPEPLD 3 0.05 0.26 0
37 INT343060 Negative_regulation of Gene_expression of Pld4 1 0.34 0 0
38 INT343071 Negative_regulation of Gene_expression of Pld2 1 0.18 0.1 0
39 INT343067 Regulation of Pld4 1 0.21 0 0
40 INT326876 Transcription of PLD2 1 0.57 0.27 0
41 INT326873 Regulation of Transcription of PLD2 1 0.37 0.22 0
42 INT343063 Positive_regulation of Gene_expression of Pld4 1 0.39 0 0
43 INT206659 Positive_regulation of Positive_regulation of NAPEPLD 1 0.07 0.18 0
44 INT343072 Binding of Pld4 1 0.28 0 0
45 INT326871 Regulation of Gene_expression of PLD2 1 0.37 1.28 0
46 INT326880 Negative_regulation of Gene_expression of PLD2 1 0.35 1.19 0
47 INT257730 Protein_catabolism of NAPEPLD 1 0.12 0.11 0
48 INT257729 Transcription of NAPEPLD 1 0.10 0.28 0
49 INT343065 Positive_regulation of Transcription of Pld4 1 0.39 0.16 0
50 INT343074 Positive_regulation of Pld2 1 0.17 0 0
51 INT343061 Negative_regulation of Transcription of Pld4 1 0.34 0.07 0
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