GO:0070301

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Name cellular response to hydrogen peroxide
Categary Process
Go Slim No
Go Link GO:0070301
Unique Molecular Interactions 1182
Total Molecular Interactions 1796
Total Single Events 15202
Pain Genes Associated 44

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cellular response to hydrogen peroxide. They are ordered first by their pain relevance and then by number of times they were reported for cellular response to hydrogen peroxide. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT254001 Binding of Cxcr4 and Mif 1 0.52 14.17 7.18
2 INT79759 Ngf Regulation of Il6 1 0.60 4.62 5.62
3 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
4 INT69032 IL18 Positive_regulation of IFNA1 12 0.23 7.87 3.83
5 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
6 INT91271 Mtr Regulation of Gene_expression of Il6 1 0.20 0 3.17
7 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
8 INT150888 Il1a Regulation of Il6 1 0.10 3.47 2.93
9 INT86180 SFTPA1 Positive_regulation of Localization of IL6 2 0.06 2.01 2.85
10 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79
11 INT69030 IL18 Positive_regulation of IL12A 3 0.31 5.57 2.72
12 INT154187 Il6 Positive_regulation of Gene_expression of Cd2 1 0.08 3.07 2.71
13 INT154188 Il6 Positive_regulation of Gene_expression of Atf3 1 0.76 3.07 2.71
14 INT253988 Binding of Cd74 and Mif 1 0.36 6.57 2.52
15 INT294909 Pax3 Positive_regulation of Gene_expression of Il6 1 0.09 5.43 2.51
16 INT287746 Anxa1 Positive_regulation of Gene_expression of Lpar1 1 0.07 1.72 2.46
17 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36
18 INT124121 IL6 Positive_regulation of CCL2 1 0.26 1.84 2.25
19 INT126717 Binding of Il6 and Il6st 3 0.21 3.35 2.22
20 INT124120 IL6 Regulation of CCL2 1 0.15 1.8 2.22
21 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
22 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
23 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
24 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
25 INT126400 ITIH4 Positive_regulation of Gene_expression of Il6 1 0.00 2.11 2.08
26 INT70043 IL6 Regulation of IL10 3 0.18 3.59 2.01
27 INT164784 Il6 Positive_regulation of Gene_expression of Cx3cr1 1 0.47 2.37 1.98
28 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
29 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
30 INT102130 Il6 Positive_regulation of Gene_expression of Crp 4 0.05 7.39 1.91
31 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
32 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87
33 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
34 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68
35 INT158774 Mapk14 Regulation of Il6 1 0.11 0.08 1.57
36 INT76651 Cpe Positive_regulation of Gene_expression of Il6 1 0.08 0 1.56
37 INT182097 Binding of Il6 and Il1 4 0.07 4.67 1.55
38 INT135276 Gt(pU21)50Imeg Negative_regulation of Gene_expression of Il6 1 0.02 0.52 1.52
39 INT76656 POMC Positive_regulation of Gene_expression of Il6 1 0.03 0 1.51
40 INT240057 Binding of RHOB and NME8 1 0.41 4.11 1.5
41 INT126718 Binding of Il6 and Il6r 3 0.09 2.33 1.49
42 INT340300 Ea1 Positive_regulation of Gene_expression of Sirt1 1 0.08 1.68 1.49
43 INT150885 Il6 Regulation of Il10 1 0.22 1.74 1.47
44 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46
45 INT155371 VIP Positive_regulation of Localization of IL6 1 0.64 3.37 1.44
46 INT236365 Binding of CD40LG and IL6 3 0.20 4.16 1.42
47 INT172834 Binding of IL6 and T2dm2 1 0.00 6.4 1.4
48 INT223156 Il6 Regulation of A2m 1 0.11 2.79 1.39
49 INT218309 Binding of CRP and IL6 3 0.23 4.78 1.36
50 INT177457 Il1 Positive_regulation of Gene_expression of Il6 3 0.16 4.47 1.35
51 INT176368 IL18 Positive_regulation of Gene_expression of IFNA1 1 0.16 2.53 1.35
52 INT160586 IL6 Positive_regulation of Gene_expression of OPRM1 1 0.14 0.54 1.35
53 INT160585 IL18 Positive_regulation of Gene_expression of OPRM1 1 0.09 0.54 1.35
54 INT136603 Calca Positive_regulation of Localization of Il6 1 0.67 0.78 1.32
55 INT182096 Positive_regulation of Binding of Il6 and Il1 2 0.09 4.26 1.31
56 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 0.03 0.76 1.25
57 INT342165 Binding of Aqp1 and Nav1 1 0.25 0.57 1.25
58 INT121190 KCNMA1 Positive_regulation of Gene_expression of IL6 1 0.03 0.54 1.24
59 INT151658 F3 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
60 INT283426 Binding of Lcn2 and Nt5e 1 0.08 5.8 1.24
61 INT121189 KCNMA1 Positive_regulation of IL6 1 0.04 0.54 1.23
62 INT253999 Binding of Cxcl12 and Mif 1 0.41 2.26 1.22
63 INT70033 IL6 Regulation of PRF1 1 0.03 1.42 1.21
64 INT70047 IL6 Regulation of Negative_regulation of PRF1 1 0.03 1.42 1.21
65 INT70029 IL6 Regulation of Negative_regulation of IL10 1 0.05 1.42 1.21
66 INT353338 F2r Positive_regulation of Localization of Mif 1 0.68 1.25 1.16
67 INT195117 Ptgs2 Positive_regulation of Gene_expression of Il6 1 0.10 3.26 1.16
68 INT185321 Tlr4 Positive_regulation of Gene_expression of Il6 5 0.14 1.97 1.15
69 INT290667 Il6 Positive_regulation of Stat3 3 0.69 2.42 1.15
70 INT94490 Il6 Positive_regulation of Gene_expression of Avp 1 0.33 1.97 1.15
71 INT94508 Il6 Positive_regulation of Gene_expression of AVP 1 0.42 1.96 1.14
72 INT294911 Pax3 Positive_regulation of Il6 1 0.06 1.78 1.14
73 INT94496 Il6 Positive_regulation of Gene_expression of Crh 1 0.29 1.94 1.12
74 INT294710 CRP Positive_regulation of Gene_expression of IL6 1 0.63 1.9 1.12
75 INT83616 Binding of IL6 and IL8 5 0.09 5.8 1.11
76 INT267588 IL10 Negative_regulation of Gene_expression of IL6 1 0.01 2.25 1.11
77 INT223154 Negative_regulation of Mapk14 Negative_regulation of Localization of Il6 1 0.19 1.13 1.11
78 INT223157 Abat Negative_regulation of Localization of Il6 1 0.05 1.13 1.1
79 INT94495 Tnf Positive_regulation of Gene_expression of Il6 1 0.30 1.9 1.09
80 INT57986 Il1b Regulation of Positive_regulation of Il6 2 0.39 0.23 1.05
81 INT120316 Ghrh Regulation of Il6 1 0.11 0.95 1.05
82 INT120310 Ghrh Regulation of Positive_regulation of Il6 1 0.18 0.95 1.05
83 INT61617 PTGER2 Regulation of Gene_expression of IL6 3 0.11 1.13 1.02
84 INT87025 ZAK Positive_regulation of Gene_expression of IL6 2 0.11 1.59 1.02
85 INT203178 IL18 Positive_regulation of Gene_expression of Lts1 1 0.01 1.98 1.02
86 INT218310 IL6 Positive_regulation of Localization of CRP 1 0.29 3.33 1.02
87 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01
88 INT278946 IL6 Regulation of Gene_expression of IL8 1 0.20 1.9 1
89 INT86181 SFTPA1 Positive_regulation of IL6 1 0.07 0.32 0.99
90 INT244133 DDB1 Positive_regulation of Gene_expression of IL6 1 0.01 1.91 0.99
91 INT154254 Tnf Positive_regulation of Il6 1 0.36 0.94 0.97
92 INT114320 TNF Positive_regulation of Gene_expression of Il6 1 0.07 1.73 0.97
93 INT272984 Il6 Positive_regulation of Gene_expression of Itgam 1 0.24 0.78 0.96
94 INT163390 Il6 Positive_regulation of Gene_expression of Crp 2 0.03 3.42 0.95
95 INT166842 Binding of ANXA1 and Nfkb1 1 0.37 1.64 0.95
96 INT299988 IL6 Positive_regulation of Localization of IL8 1 0.05 0.81 0.94
97 INT182024 TNF Positive_regulation of Gene_expression of Il6 1 0.05 1.58 0.94
98 INT285418 IRF6 Positive_regulation of Localization of IL6 3 0.05 0.66 0.93
99 INT210791 Bmp2 Positive_regulation of Net1 1 0.38 0.52 0.93
100 INT134785 Il2rb Regulation of Gene_expression of IL6 1 0.00 1.16 0.92
101 INT134784 Il2rb Regulation of IL6 1 0.00 1.16 0.92
102 INT78062 Il1a Positive_regulation of Localization of Il6 3 0.24 0.48 0.9
103 INT64717 Pomc Positive_regulation of Il6 1 0.13 0.19 0.9
104 INT40636 Mif Negative_regulation of Pomc 1 0.25 0.07 0.9
105 INT91270 Oprd1 Regulation of Gene_expression of Il6 1 0.00 0 0.89
106 INT210801 Bst2 Positive_regulation of Net1 1 0.35 0.54 0.89
107 INT159962 Rock2 Regulation of Localization of Il6 1 0.09 2.7 0.88
108 INT91273 Mtr Positive_regulation of Localization of Il6 1 0.17 0 0.88
109 INT253992 Cxcl12 Positive_regulation of Mif 1 0.46 1.31 0.88
110 INT91272 Ifng Positive_regulation of Localization of Il6 1 0.29 0 0.88
111 INT231716 Binding of IL6 and DIP 1 0.24 1.55 0.87
112 INT122350 Ngf Regulation of Hsd3b1 1 0.34 0 0.87
113 INT76652 Cpe Positive_regulation of Il6 1 0.08 0 0.87
114 INT199499 Il6 Positive_regulation of Transcription of Oprm1 1 0.01 0.8 0.86
115 INT199492 Il6 Positive_regulation of Transcription of Oprm1 1 0.01 0.81 0.86
116 INT199487 Il6 Positive_regulation of Oprm1 1 0.01 0.8 0.86
117 INT199491 Il6 Positive_regulation of Positive_regulation of Il6 1 0.00 0.81 0.86
118 INT199500 Il6 Positive_regulation of Oprm1 1 0.01 0.8 0.85
119 INT342986 PTAFR Positive_regulation of Gene_expression of IL6 1 0.14 0.39 0.84
120 INT54992 Il6 Negative_regulation of Prl 1 0.00 0.86 0.84
121 INT105435 TNF Positive_regulation of IL6 5 0.25 4.45 0.83
122 INT86430 IL6 Positive_regulation of Gene_expression of HP 1 0.15 3.61 0.83
123 INT195217 EGFL7 Negative_regulation of Gene_expression of IL6 1 0.06 1.14 0.83
124 INT342999 IL6 Positive_regulation of Gene_expression of HIST2H2AA3 1 0.00 0.4 0.83
125 INT340294 Ea1 Positive_regulation of Sirt1 1 0.06 0.53 0.83
126 INT306271 IL1A Positive_regulation of Gene_expression of IL6 1 0.30 0.85 0.8
127 INT135278 Gt(pU21)50Imeg Negative_regulation of Positive_regulation of Il6 1 0.02 0.26 0.8
128 INT160411 Tat Positive_regulation of Il6 1 0.17 0.89 0.8
129 INT226371 IL18 Positive_regulation of IL4 4 0.05 2.49 0.79
130 INT135277 Gt(pU21)50Imeg Negative_regulation of Il6 1 0.02 0.23 0.78
131 INT196577 Negative_regulation of Mapk14 Negative_regulation of Il6 1 0.13 0.45 0.78
132 INT196574 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il6 1 0.13 0.45 0.78
133 INT296792 Tlr9 Regulation of Gene_expression of Il6 1 0.06 1.36 0.76
134 INT178579 CNTN2 Positive_regulation of IL6 1 0.07 2.17 0.75
135 INT142847 IRF6 Positive_regulation of IL6 5 0.07 1.09 0.73
136 INT248271 IL6 Regulation of Gene_expression of Crp 3 0.27 1.7 0.73
137 INT331599 Tlr9 Positive_regulation of Gene_expression of Il6 1 0.03 1.8 0.73
138 INT124352 Il6 Positive_regulation of Positive_regulation of Gorasp2 1 0.10 1.19 0.73
139 INT327994 Il6 Positive_regulation of Gene_expression of ROS1 1 0.05 0.55 0.73
140 INT172134 Binding of IL6 and IL15 2 0.01 1.18 0.72
141 INT237325 Il6 Positive_regulation of Gene_expression of Ik 2 0.00 2.09 0.72
142 INT209057 Il6 Positive_regulation of Csf2 1 0.03 0.38 0.72
143 INT209039 Il6 Positive_regulation of Il17a 1 0.05 0.38 0.72
144 INT209056 Il6 Positive_regulation of Elf1 1 0.10 0.38 0.72
145 INT209059 Il6 Positive_regulation of Cxcl1 1 0.06 0.38 0.72
146 INT150996 Sfpq Positive_regulation of Gene_expression of Il6 1 0.04 0.7 0.72
147 INT236364 CD40LG Positive_regulation of Gene_expression of IL6 1 0.25 1.37 0.72
148 INT209060 Il6 Positive_regulation of Ccr1 1 0.01 0.38 0.72
149 INT51005 PDYN Positive_regulation of IL6 1 0.08 0.84 0.72
150 INT260551 Igh-Dex Negative_regulation of Il6 1 0.09 0.37 0.72
151 INT159963 Tnf Positive_regulation of Localization of Il6 1 0.12 2.32 0.71
152 INT89936 Tlr4 Positive_regulation of Il6 3 0.49 0.95 0.7
153 INT224580 Gene_expression of IL18 Positive_regulation of SERPINH1 1 0.00 1.34 0.7
154 INT40703 Mif Negative_regulation of Negative_regulation of POMC 1 0.24 0.49 0.7
155 INT91700 Il6 Negative_regulation of Oprd1 1 0.23 0 0.7
156 INT346267 Binding of HGF and IL6 1 0.04 0.96 0.7
157 INT215098 Tlr4 Positive_regulation of Localization of Il6 3 0.18 1.18 0.69
158 INT278968 LEP Regulation of Gene_expression of IL6 1 0.29 1.11 0.69
159 INT253994 Cyp3a23/3a1 Positive_regulation of Localization of Mif 1 0.09 0.96 0.69
160 INT253759 Hmgb1 Positive_regulation of Apex1 1 0.09 4.53 0.69
161 INT150998 Sfpq Negative_regulation of Gene_expression of Il6 1 0.05 0.69 0.69
162 INT325270 Il33 Positive_regulation of Gene_expression of Il6 1 0.20 1.59 0.69
163 INT76655 POMC Positive_regulation of Transcription of Il6 1 0.01 0 0.68
164 INT76654 Cpe Positive_regulation of Transcription of Il6 1 0.05 0 0.68
165 INT203758 Binding of IL6 and TNF 3 0.26 2.03 0.67
166 INT278953 IL6 Regulation of Gene_expression of PTGER2 1 0.04 1.38 0.67
167 INT102350 P2rx1 Negative_regulation of Localization of Il6 1 0.32 0 0.67
168 INT164782 Il6 Regulation of Gene_expression of Cx3cr1 1 0.27 0.79 0.67
169 INT320152 IL6 Positive_regulation of IL1RN 2 0.23 2.59 0.66
170 INT82384 Penk Positive_regulation of Gene_expression of Il6 1 0.15 0 0.66
171 INT285943 IL17A Positive_regulation of Localization of IL6 3 0.20 2.02 0.65
172 INT121812 IL6 Regulation of OPRM1 1 0.22 0.27 0.65
173 INT209054 Il17a Positive_regulation of Gene_expression of Il6 1 0.10 0.45 0.65
174 INT191494 IL6 Positive_regulation of Binding of CRP 1 0.02 1.65 0.65
175 INT209055 S100a8 Positive_regulation of Gene_expression of Il6 1 0.01 0.45 0.64
176 INT64956 IRF6 Positive_regulation of Gene_expression of IL6 4 0.19 1.4 0.63
177 INT183387 Il6 Positive_regulation of Gene_expression of Il10 2 0.19 1.8 0.63
178 INT220117 Il6 Positive_regulation of TNF 1 0.01 2.45 0.63
179 INT121188 Negative_regulation of KCNMA1 Positive_regulation of IL6 1 0.04 0.3 0.63
180 INT155458 Tnfrsf1a Regulation of Gene_expression of Il6 1 0.22 1.11 0.63
181 INT71526 Regulation of Il1b Positive_regulation of Il6 1 0.17 0.14 0.62
182 INT264335 Binding of IL-17 and Positive_regulation of Localization of Il6 1 0.13 1.62 0.62
183 INT71527 Negative_regulation of OPRD1 Negative_regulation of Positive_regulation of Il6 1 0.00 0.15 0.62
184 INT285939 IL6 Positive_regulation of TEP1 1 0.01 1.76 0.61
185 INT132731 Positive_regulation of Binding of Il1b and Il6 1 0.46 1.2 0.61
186 INT169294 EGF Positive_regulation of Localization of IL6 1 0.18 0.13 0.61
187 INT323773 Binding of Il6 and Lep 1 0.29 3.54 0.6
188 INT71525 Oprd1 Regulation of Il6 1 0.16 0.19 0.6
189 INT327167 RETNLB Regulation of IL6 1 0.00 2.26 0.6
190 INT91699 Il6 Regulation of Gene_expression of Oprl1 1 0.06 0 0.6
191 INT164990 Mif Positive_regulation of Gene_expression of Grina 1 0.24 0.53 0.6
192 INT65014 SOS1 Positive_regulation of Gene_expression of IL6 1 0.45 0.42 0.6
193 INT140890 Il10 Regulation of Il6 1 0.35 0.73 0.58
194 INT253760 Hmgb1 Positive_regulation of Gene_expression of Apex1 1 0.10 3.53 0.58
195 INT205705 Positive_regulation of P2rx7 Positive_regulation of Gene_expression of Il6 1 0.07 1.42 0.58
196 INT184100 Il6 Positive_regulation of Stat1 1 0.16 0.68 0.58
197 INT121813 IL6 Positive_regulation of OPRM1 1 0.28 0.28 0.58
198 INT297331 Apoe Negative_regulation of Gene_expression of Il6 1 0.14 0.61 0.57
199 INT151461 Olr1745 Negative_regulation of Gene_expression of Il6 1 0.03 0.81 0.57
200 INT142312 Lalba Negative_regulation of Localization of Il6 1 0.23 0.73 0.57

Single Events

The table below shows the top 100 pain related interactions that have been reported for cellular response to hydrogen peroxide. They are ordered first by their pain relevance and then by number of times they were reported in cellular response to hydrogen peroxide. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22
2 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57
3 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57
4 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59
5 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38
6 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28
7 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3
8 INT12082 Localization of IL6 365 0.81 241.78 105.78
9 INT19511 Localization of Il6 212 0.81 118.17 67.67
10 INT11937 Localization of Il6 228 0.81 139.83 64.39
11 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6
12 INT10706 Regulation of Il6 150 0.62 93.23 62.34
13 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87
14 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78
15 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15
16 INT9210 Regulation of IL6 166 0.62 125.61 49.95
17 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67
18 INT11939 Negative_regulation of Il6 138 0.59 87.46 41.24
19 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53
20 INT9658 Negative_regulation of Gene_expression of Il6 110 0.59 66.29 32.58
21 INT9655 Regulation of Il6 98 0.62 70.92 31.95
22 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07
23 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52
24 INT86437 Binding of IL6 154 0.48 121.22 29.3
25 INT104567 Gene_expression of Aqp1 47 0.78 44.84 28.68
26 INT116737 Localization of Mif 63 0.81 52.97 28.11
27 INT69036 Gene_expression of IL18 99 0.77 77.92 25.95
28 INT51474 Binding of Il6 55 0.48 44.99 20.52
29 INT49985 Transcription of Il6 62 0.72 40.13 20.29
30 INT40750 Gene_expression of Mif 61 0.78 34.59 20.28
31 INT51054 Negative_regulation of Localization of IL6 45 0.59 24.48 18.97
32 INT87861 Gene_expression of Il18 33 0.78 30.44 18.42
33 INT11938 Positive_regulation of Localization of Il6 61 0.70 35.72 18.25
34 INT61626 Transcription of IL6 73 0.72 42.04 17.86
35 INT9656 Regulation of Gene_expression of Il6 57 0.62 33.3 17.71
36 INT50932 Positive_regulation of Positive_regulation of Il6 36 0.69 24.9 16.12
37 INT116736 Positive_regulation of Mif 40 0.70 31.93 15.37
38 INT49532 Regulation of Gene_expression of Il6 43 0.61 25.8 14.99
39 INT49376 Negative_regulation of Localization of Il6 37 0.59 12.66 14.99
40 INT59870 Gene_expression of F3 51 0.65 51.83 14.01
41 INT55256 Negative_regulation of Localization of Il6 38 0.58 16.12 13.67
42 INT54763 Binding of Il6 82 0.48 63.27 12.89
43 INT55255 Positive_regulation of Localization of Il6 48 0.69 24.88 12.76
44 INT12084 Regulation of Localization of IL6 36 0.61 20.32 12.34
45 INT114674 Gene_expression of Mdm2 15 0.78 3.51 11.85
46 INT72949 Binding of Mif 31 0.46 23.12 11.65
47 INT50933 Transcription of Il6 38 0.72 24.31 11.58
48 INT49396 Negative_regulation of Positive_regulation of Il6 29 0.59 16.39 11.31
49 INT11936 Positive_regulation of Positive_regulation of Il6 34 0.50 26.85 10.59
50 INT62544 Gene_expression of Anxa1 21 0.47 13.56 9.71
51 INT87863 Positive_regulation of IL18 40 0.69 34.08 9.53
52 INT11047 Positive_regulation of Positive_regulation of IL6 45 0.66 28.7 9.37
53 INT152668 Negative_regulation of EP300 13 0.38 7.78 9.03
54 INT44003 Gene_expression of F3 40 0.75 27.92 8.29
55 INT114675 Positive_regulation of Gene_expression of Mdm2 1 0.70 1.98 7.9
56 INT87139 Negative_regulation of Positive_regulation of Il6 18 0.59 10.65 7.76
57 INT94127 Positive_regulation of Il18 14 0.69 14 7.47
58 INT91721 Binding of IL18 21 0.48 21.17 6.56
59 INT517 Regulation of Mif 16 0.62 5.43 6.55
60 INT8683 Positive_regulation of F3 31 0.67 42.89 6.21
61 INT91657 Negative_regulation of IL18 20 0.48 15.97 6.12
62 INT516 Negative_regulation of Mif 13 0.59 6.69 6.08
63 INT677 Positive_regulation of CST3 20 0.67 17.47 6
64 INT64724 Positive_regulation of Transcription of IL6 26 0.69 13.63 5.96
65 INT4613 Positive_regulation of Sirt1 32 0.67 18.19 5.53
66 INT113420 Positive_regulation of Gene_expression of IL18 22 0.69 19.96 5.53
67 INT64716 Regulation of Positive_regulation of Il6 7 0.54 2.83 5.34
68 INT156134 Regulation of Gene_expression of Aqp1 5 0.59 7.2 5.3
69 INT64723 Regulation of Positive_regulation of IL6 13 0.61 12.59 5.19
70 INT14501 Gene_expression of CST3 28 0.75 25.77 5.16
71 INT49375 Regulation of Localization of Il6 16 0.62 4.54 5.08
72 INT174339 Positive_regulation of Localization of Mif 7 0.61 8.27 4.95
73 INT85328 Negative_regulation of Aqp1 5 0.54 6.02 4.94
74 INT240934 Gene_expression of Sirt1 24 0.75 18.77 4.68
75 INT131808 Localization of Apex1 2 0.16 13.46 4.61
76 INT79902 Gene_expression of AQP1 33 0.78 24.72 4.55
77 INT2213 Regulation of EP300 10 0.54 4.72 4.5
78 INT52133 Regulation of Localization of Il6 7 0.61 5.35 4.37
79 INT41878 Positive_regulation of EP300 13 0.61 5.24 3.95
80 INT35175 Localization of IL18 18 0.80 12.96 3.83
81 INT116738 Positive_regulation of Gene_expression of Mif 14 0.68 10.99 3.8
82 INT78493 Negative_regulation of F3 11 0.27 8.35 3.76
83 INT85326 Positive_regulation of Aqp1 7 0.65 5.9 3.71
84 INT85497 Gene_expression of Anxa1 6 0.77 4.7 3.68
85 INT142753 Gene_expression of Lcn2 28 0.76 10.03 3.62
86 INT66924 Positive_regulation of Transcription of Il6 18 0.68 11.8 3.53
87 INT104570 Localization of Aqp1 8 0.77 5.83 3.51
88 INT148151 Regulation of Il18 7 0.28 5.4 3.5
89 INT64725 Regulation of Transcription of IL6 9 0.45 7.96 3.49
90 INT81403 Positive_regulation of Regulation of Il6 4 0.44 1.81 3.37
91 INT64715 Phosphorylation of Il6 7 0.81 4.24 3.36
92 INT62547 Positive_regulation of Gene_expression of Anxa1 5 0.42 4.52 3.27
93 INT48042 Positive_regulation of Anxa1 5 0.50 3.64 3.19
94 INT94947 Positive_regulation of Transcription of Il6 9 0.67 6.91 3.04
95 INT134798 Gene_expression of ANXA1 15 0.75 13.94 2.99
96 INT105783 Protein_catabolism of IL6 7 0.48 4.72 2.95
97 INT176383 Negative_regulation of Binding of IL18 1 0.35 5.91 2.91
98 INT84527 Positive_regulation of Gene_expression of F3 16 0.49 15.83 2.85
99 INT139562 Transcription of IL18 10 0.68 6.14 2.73
100 INT64714 Positive_regulation of Phosphorylation of Il6 4 0.50 3.22 2.67
101 INT151029 Positive_regulation of Gene_expression of Lcn2 8 0.68 4.04 2.65
102 INT174687 Regulation of Positive_regulation of Il6 10 0.61 9.07 2.61
103 INT222289 Localization of Il18 4 0.30 3.24 2.58
104 INT165726 Positive_regulation of Anxa1 7 0.29 3.16 2.57
105 INT136850 Positive_regulation of Arg1 10 0.50 6.96 2.47
106 INT159604 Gene_expression of IL18BP 3 0.49 4.56 2.42
107 INT138785 Gene_expression of Lcn2 9 0.56 9.88 2.41
108 INT10558 Regulation of Regulation of IL6 6 0.45 4.94 2.33
109 INT133567 Regulation of IL18 11 0.50 9.54 2.31
110 INT171511 Gene_expression of EP300 14 0.53 4.17 2.29
111 INT640 Regulation of CST3 9 0.60 4.04 2.26
112 INT46088 Localization of F3 15 0.37 13.7 2.23
113 INT148152 Binding of Il18 4 0.46 4.44 2.19
114 INT166838 Positive_regulation of ANXA1 4 0.64 4.88 2.16
115 INT2611 Negative_regulation of AQP1 17 0.39 10.04 2.15
116 INT141721 Binding of Aqp1 5 0.37 1.77 2.15
117 INT58469 Negative_regulation of Positive_regulation of IL6 16 0.42 8.1 2.14
118 INT203308 Regulation of Aqp1 4 0.48 2.59 2.13
119 INT221409 Regulation of Sirt1 8 0.58 5.53 2.1
120 INT94128 Positive_regulation of Gene_expression of Il18 6 0.50 3.64 2.06
121 INT52197 Negative_regulation of Transcription of Il6 8 0.43 3.8 2.05
122 INT118305 Negative_regulation of Gene_expression of IL18 7 0.39 6.52 2.05
123 INT98888 Negative_regulation of Gene_expression of Il18 3 0.43 1.72 2.02
124 INT171514 Binding of EP300 13 0.32 4.32 2.01
125 INT151036 Positive_regulation of Lcn2 13 0.49 8.57 2
126 INT244704 Gene_expression of ARG1 65 0.75 37.74 1.9
127 INT14500 Positive_regulation of Gene_expression of CST3 9 0.67 7.46 1.87
128 INT64959 Positive_regulation of Negative_regulation of IL6 5 0.42 5.16 1.86
129 INT9106 Positive_regulation of F3 8 0.22 4.92 1.85
130 INT240058 Gene_expression of RHOB 2 0.55 4.29 1.84
131 INT253756 Gene_expression of Apex1 1 0.14 7.47 1.84
132 INT122346 Gene_expression of Hsd3b1 1 0.75 0 1.78
133 INT155455 Negative_regulation of Phosphorylation of Il6 1 0.31 2.5 1.76
134 INT172622 Localization of EP300 8 0.65 2.56 1.72
135 INT85498 Positive_regulation of Gene_expression of Anxa1 3 0.50 2.12 1.7
136 INT135275 Regulation of Negative_regulation of Il6 4 0.45 0.89 1.67
137 INT44149 Regulation of Gene_expression of Mif 6 0.54 2.45 1.63
138 INT283399 Binding of Lcn2 1 0.47 5.48 1.61
139 INT240059 Binding of RHOB 7 0.48 3.96 1.59
140 INT138786 Positive_regulation of Lcn2 7 0.51 3.41 1.59
141 INT353326 Negative_regulation of Localization of Mif 1 0.45 1.28 1.59
142 INT60975 Localization of CST3 6 0.78 2.4 1.58
143 INT176382 Negative_regulation of IL18BP 1 0.19 3.16 1.56
144 INT216932 Positive_regulation of Negative_regulation of Il6 3 0.38 4.88 1.55
145 INT85499 Regulation of Anxa1 1 0.27 1.88 1.52
146 INT255787 Positive_regulation of Gene_expression of Sirt1 9 0.67 7.61 1.5
147 INT159605 Binding of IL18BP 2 0.24 2.56 1.5
148 INT289575 Gene_expression of Sirt1 47 0.77 29.29 1.47
149 INT98448 Regulation of Binding of Il6 3 0.39 2.6 1.46
150 INT77368 Regulation of Regulation of Il6 3 0.35 1.86 1.45
151 INT98449 Positive_regulation of Binding of Il6 3 0.44 2.96 1.44
152 INT87062 Positive_regulation of Binding of IL6 10 0.49 11.8 1.42
153 INT211054 Positive_regulation of AQP1 3 0.33 4.53 1.41
154 INT114671 Positive_regulation of Mdm2 1 0.61 0.5 1.38
155 INT327824 Positive_regulation of Gene_expression of Aqp1 4 0.67 5.4 1.37
156 INT73553 Gene_expression of Aqp1 23 0.67 4.65 1.34
157 INT138782 Negative_regulation of Lcn2 3 0.31 1.21 1.34
158 INT122345 Positive_regulation of Gene_expression of Hsd3b1 1 0.49 0 1.34
159 INT151038 Localization of Lcn2 4 0.79 1.87 1.32
160 INT159598 Positive_regulation of Transcription of IL18 3 0.48 1.84 1.32
161 INT69037 Regulation of Gene_expression of IL18 4 0.43 3.29 1.31
162 INT164706 Positive_regulation of Park7 2 0.50 2.28 1.28
163 INT253987 Regulation of Localization of Mif 3 0.43 1.65 1.27
164 INT679 Negative_regulation of CST3 7 0.57 4.63 1.22
165 INT146755 Regulation of Lcn2 6 0.26 2.5 1.22
166 INT190075 Regulation of Transcription of Il6 2 0.45 2.17 1.18
167 INT176379 Regulation of Binding of IL18 1 0.37 2.37 1.17
168 INT176387 Negative_regulation of Binding of IL18BP 1 0.14 2.37 1.16
169 INT121368 Transcription of Mif 5 0.72 2.71 1.15
170 INT138784 Positive_regulation of Gene_expression of Lcn2 3 0.49 4.44 1.13
171 INT36064 Binding of CST3 14 0.47 16.38 1.12
172 INT10559 Negative_regulation of Regulation of IL6 4 0.37 1.76 1.1
173 INT88820 Positive_regulation of Gene_expression of F3 8 0.67 5.48 1.08
174 INT35174 Positive_regulation of Localization of IL18 7 0.69 5.22 1.08
175 INT71233 Negative_regulation of Anxa1 1 0.07 0.15 1.05
176 INT289553 Positive_regulation of Gene_expression of Sirt1 21 0.69 20.43 1.03
177 INT168065 Binding of Sirt1 13 0.47 4.55 1.02
178 INT114673 Regulation of Gene_expression of Mdm2 1 0.62 0.23 1.02
179 INT228871 Negative_regulation of Gene_expression of Anxa1 2 0.03 1.92 1.01
180 INT167650 Binding of Ep300 1 0.09 0.14 1
181 INT122151 Localization of Anxa1 1 0.75 0.53 1
182 INT166889 Positive_regulation of Gene_expression of AQP1 10 0.70 6.43 0.99
183 INT134260 Negative_regulation of Transcription of Il6 2 0.25 1.39 0.99
184 INT122347 Transcription of Hsd3b1 1 0.52 0 0.99
185 INT44002 Negative_regulation of Gene_expression of F3 5 0.20 1.64 0.98
186 INT152021 Regulation of Negative_regulation of IL6 3 0.32 1.38 0.98
187 INT156727 Gene_expression of Arg1 4 0.44 2.1 0.97
188 INT151035 Negative_regulation of Lcn2 5 0.42 1.99 0.96
189 INT352919 Positive_regulation of Gene_expression of RHOB 1 0.35 2.21 0.96
190 INT64958 Negative_regulation of Transcription of IL6 6 0.50 3.58 0.92
191 INT183362 Regulation of AQP1 3 0.23 1.49 0.92
192 INT24372 Negative_regulation of Sphk1 1 0.59 0 0.85
193 INT115192 Phosphorylation of IL6 7 0.70 1.55 0.84
194 INT192851 Phosphorylation of Il6 7 0.68 3.12 0.82
195 INT295239 Negative_regulation of Anxa1 2 0.02 1.6 0.81
196 INT353328 Regulation of Positive_regulation of Mif 1 0.40 0.89 0.81
197 INT289550 Positive_regulation of Sirt1 25 0.69 13.59 0.8
198 INT176388 Localization of IL18BP 2 0.68 1.42 0.78
199 INT300843 Regulation of Transcription of Il6 3 0.37 3.4 0.76
200 INT258791 Positive_regulation of CDK1 14 0.45 5.73 0.74
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