GO:0070307

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Name lens fiber cell development
Categary Process
Go Slim No
Go Link GO:0070307
Unique Molecular Interactions 52
Total Molecular Interactions 84
Total Single Events 941
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for lens fiber cell development. They are ordered first by their pain relevance and then by number of times they were reported for lens fiber cell development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT229497 Binding of Vim and Ndel1 1 0.33 3.5 2.81
2 INT127738 Binding of Crygb and Pnoc 2 0.49 0.1 0.99
3 INT346227 Binding of PRTN3 and Vim 1 0.01 0.93 0.38
4 INT155478 Binding of Gast and Vim 1 0.51 0.6 0.35
5 INT128541 Pnoc Positive_regulation of Crygb 1 0.21 0 0.29
6 INT229502 Binding of Vim and Gopc 1 0.05 0.42 0.23
7 INT163863 Binding of MIB1 and Vim 1 0.02 1.06 0.21
8 INT4987 Vim Positive_regulation of Lrrc23 1 0.00 0.42 0.14
9 INT148593 Binding of Gfap and Vim 1 0.06 1.25 0.13
10 INT182367 IgG Regulation of Vim 1 0.00 0.99 0.11
11 INT137398 Binding of CD99 and Vim 2 0.02 2.36 0.09
12 INT52944 Binding of SERPINA3 and Vim 1 0.01 0.43 0.09
13 INT157738 GFAP Regulation of Vim 1 0.04 0.97 0.08
14 INT68004 Binding of Hba-a1 and Vim 1 0.00 1.3 0.08
15 INT229501 Binding of Nefl and Vim 1 0.05 0.32 0.08
16 INT303561 Binding of Fgf7 and Fgfr2 1 0.42 0.88 0.07
17 INT229500 Binding of Vim and Nde1 1 0.00 0.79 0.07
18 INT303560 Binding of Fgfr2 and Fgf22 1 0.41 0.89 0.07
19 INT303562 Binding of Fgf10 and Fgfr2 1 0.40 0.88 0.07
20 INT341680 Binding of DES and Vim 1 0.02 0.59 0.06
21 INT250865 Binding of Fgf8 and Fgfr3 1 0.18 0.3 0.05
22 INT250855 Binding of Fgfr2 and Fgf8 1 0.12 0.3 0.05
23 INT229490 Binding of Vim and Kpna4 1 0.02 0.21 0.04
24 INT229499 Nde1 Regulation of Vim 1 0.00 0.35 0.04
25 INT229505 Ndel1 Negative_regulation of Vim 1 0.29 0.14 0.04
26 INT229498 Binding of Vim and Mapk1 1 0.03 0.21 0.04
27 INT303558 Binding of Fgfr2 and Dysf 1 0.01 0.44 0.03
28 INT182688 Binding of Vim and Fig4 1 0.08 0.07 0
29 INT341005 Binding of Vim and Nrg1 1 0.05 0.14 0
30 INT182685 Binding of Vim and Son 1 0.22 0.23 0
31 INT341025 PIK3CB Positive_regulation of Regulation of Vim 1 0.01 0 0
32 INT298451 Binding of SNAI1 and Vim 1 0.07 1.45 0
33 INT296670 Binding of Bcl2 and Vim 1 0.00 1.31 0
34 INT341012 Binding of Fabp7 and Vim 1 0.03 0.16 0
35 INT155479 Vim Positive_regulation of Gast 1 0.47 0 0
36 INT298449 Binding of ITK and Vim 1 0.01 0.58 0
37 INT202675 Fgf10 Positive_regulation of Fgfr2 1 0.45 0.07 0
38 INT341001 Binding of Reln and Vim 1 0.02 0.14 0
39 INT301366 Fgf18 Positive_regulation of Fgfr3 1 0.04 0.34 0
40 INT341010 Nrg1 Positive_regulation of Regulation of Vim 1 0.07 0 0
41 INT185273 Vim Regulation of Psmd1 1 0.01 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for lens fiber cell development. They are ordered first by their pain relevance and then by number of times they were reported in lens fiber cell development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5841 Gene_expression of Vim 181 0.72 138.54 16.33
2 INT4991 Positive_regulation of Vim 74 0.69 69.84 8.33
3 INT122080 Positive_regulation of Crygb 10 0.45 4.32 7.14
4 INT26585 Gene_expression of Vim 117 0.77 39.97 6
5 INT110520 Negative_regulation of Crygb 6 0.31 2.32 4.71
6 INT122078 Gene_expression of Crygb 7 0.76 1.25 4.34
7 INT110521 Regulation of Crygb 5 0.28 1.42 2.92
8 INT27935 Binding of Vim 21 0.36 15.65 2.61
9 INT122332 Binding of Crygb 2 0.48 0 2.55
10 INT5844 Positive_regulation of Gene_expression of Vim 14 0.25 9.64 2.18
11 INT23955 Regulation of Vim 16 0.25 14.21 2.04
12 INT122077 Positive_regulation of Gene_expression of Crygb 1 0.32 0.09 1.87
13 INT229479 Positive_regulation of Vim 14 0.43 1.77 1.35
14 INT155477 Binding of Vim 13 0.47 2.24 1.12
15 INT169703 Positive_regulation of Gene_expression of Vim 7 0.38 2.56 1.09
16 INT165962 Transcription of Vim 3 0.39 1.47 1.01
17 INT169707 Regulation of Gene_expression of Vim 3 0.29 1.11 0.88
18 INT118469 Gene_expression of Fgfr3 5 0.72 6.98 0.75
19 INT76005 Regulation of Binding of Vim 1 0.02 0 0.72
20 INT146778 Negative_regulation of Fgfr2 1 0.32 0.66 0.48
21 INT229465 Localization of Vim 6 0.47 1.23 0.47
22 INT166312 Negative_regulation of Vim 7 0.22 5.9 0.46
23 INT202626 Negative_regulation of Fgfr2 2 0.41 2.48 0.42
24 INT76690 Negative_regulation of Gene_expression of Vim 1 0.39 1.4 0.42
25 INT166698 Localization of Vim 3 0.18 1.13 0.4
26 INT133792 Phosphorylation of Vim 2 0.32 1.34 0.3
27 INT155476 Regulation of Binding of Vim 2 0.61 0.73 0.29
28 INT233863 Protein_catabolism of Vim 1 0.07 0.81 0.25
29 INT176080 Gene_expression of Fgfr2 4 0.68 2.34 0.24
30 INT229471 Regulation of Vim 4 0.28 0.86 0.22
31 INT223739 Binding of Fgfr2 3 0.30 0.94 0.22
32 INT92374 Protein_catabolism of Vim 1 0.76 0.46 0.19
33 INT229475 Negative_regulation of Vim 5 0.37 0.81 0.12
34 INT182694 Regulation of Gene_expression of Vim 2 0.24 1.01 0.12
35 INT229458 Negative_regulation of Gene_expression of Vim 6 0.36 0.45 0.09
36 INT107387 Positive_regulation of Positive_regulation of Vim 1 0.25 0.69 0.08
37 INT250839 Binding of Fgfr3 1 0.16 0.19 0.08
38 INT228669 Positive_regulation of Localization of Vim 1 0.12 0.34 0.07
39 INT49625 Negative_regulation of Positive_regulation of Vim 1 0.22 1.33 0.07
40 INT303546 Binding of Fgfr2 1 0.46 0.74 0.06
41 INT243717 Positive_regulation of Phosphorylation of Vim 1 0.22 0.47 0.04
42 INT270865 Positive_regulation of Transcription of Vim 1 0.21 0.16 0.04
43 INT243716 Phosphorylation of Vim 1 0.26 0.46 0.04
44 INT303525 Localization of Fgfr2 1 0.72 0.28 0.03
45 INT303547 Positive_regulation of Negative_regulation of Fgfr2 1 0.48 1.07 0.03
46 INT206486 Transcription of Vim 2 0.56 0.06 0
47 INT276327 Positive_regulation of Gene_expression of Fgfr3 2 0.43 1.83 0
48 INT243057 Positive_regulation of Fgfr3 1 0.46 0.79 0
49 INT202623 Negative_regulation of Gene_expression of Fgfr2 1 0.32 0 0
50 INT319036 Gene_expression of Fgfr2 1 0.48 0.08 0
51 INT303553 Regulation of Gene_expression of Fgfr3 1 0.25 0.3 0
52 INT243058 Positive_regulation of Positive_regulation of Fgfr3 1 0.46 0.8 0
53 INT309967 Positive_regulation of Binding of Vim 1 0.13 0 0
54 INT340951 Negative_regulation of Localization of Vim 1 0.10 0 0
55 INT340976 Negative_regulation of Negative_regulation of Vim 1 0.10 0 0
56 INT301359 Positive_regulation of Fgfr3 1 0.19 0.64 0
57 INT301357 Negative_regulation of Positive_regulation of Fgfr3 1 0.16 0.35 0
58 INT229480 Negative_regulation of Positive_regulation of Vim 1 0.27 0.09 0
59 INT303524 Positive_regulation of Fgfr2 1 0.66 0.22 0
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