GO:0070411

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Name I-SMAD binding
Categary Function
Go Slim No
Go Link GO:0070411
Unique Molecular Interactions 131
Total Molecular Interactions 156
Total Single Events 854
Pain Genes Associated 21

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for I-SMAD binding. They are ordered first by their pain relevance and then by number of times they were reported for I-SMAD binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT75486 Binding of Tgfbr1 and Tgfbr2 1 0.10 1.94 1.02
2 INT161951 Positive_regulation of TGFBR1 Positive_regulation of Gene_expression of Ngf 1 0.27 0.99 0.76
3 INT161945 TGFB2 Positive_regulation of TGFBR1 1 0.08 0.99 0.76
4 INT161950 TGFBR1 Negative_regulation of Localization of Ngf 1 0.23 1.01 0.72
5 INT302644 ARSA Positive_regulation of Gene_expression of TGFBR1 1 0.04 0.29 0.51
6 INT302647 ARSA Positive_regulation of TGFBR1 1 0.03 0.29 0.51
7 INT75488 Binding of TGFB1 and Tgfbr1 1 0.23 0.78 0.41
8 INT291616 Cby1 Positive_regulation of Gene_expression of Smad7 1 0.00 0.79 0.38
9 INT300609 Binding of Ctnnb1 and Wnt2 1 0.02 0.25 0.37
10 INT124378 Prodh2 Positive_regulation of Ctnnb1 1 0.00 0.59 0.35
11 INT198566 Ddit4l Regulation of Axin1 1 0.03 1 0.31
12 INT137023 Gene_expression of SMAD2 Negative_regulation of Gene_expression of Acta2 1 0.00 0.43 0.29
13 INT311918 Insrr Negative_regulation of Tgfbr1 1 0.00 0.87 0.26
14 INT311902 Acvrl1 Negative_regulation of Tgfbr1 1 0.13 0.87 0.26
15 INT311911 Tgfbr1 Positive_regulation of Gene_expression of Mmp13 1 0.10 0.55 0.23
16 INT333449 Binding of SMAD2 and SMAD4 1 0.23 0 0.17
17 INT217074 Binding of Acsm3 and Axin1 1 0.00 5.37 0.17
18 INT333447 Binding of SMAD2 and RXRA 1 0.04 0 0.16
19 INT251115 Positive_regulation of Binding of AR and Ctnnb1 1 0.01 1.02 0.13
20 INT311905 Binding of Runx2 and Smad1 1 0.12 0.46 0.13
21 INT311912 Gene_expression of Smad1 Positive_regulation of Gene_expression of Mmp13 1 0.08 0.51 0.12
22 INT172976 Mras Regulation of Gene_expression of Smad4 1 0.00 0.83 0.12
23 INT251114 Binding of AR and Ctnnb1 1 0.01 1 0.12
24 INT316823 Sparc Positive_regulation of Phosphorylation of Smad2 1 0.44 0.49 0.1
25 INT228808 Smad7 Regulation of Rgs1 1 0.19 0.24 0.09
26 INT228812 Smad7 Regulation of Stap1 1 0.00 0.24 0.09
27 INT134837 TGFB1 Regulation of SMAD7 1 0.34 0.68 0.08
28 INT311917 Gene_expression of Tgfbr1 Positive_regulation of Gene_expression of Mmp13 1 0.10 0.31 0.08
29 INT134833 TGFB1 Regulation of Gene_expression of SMAD7 1 0.34 0.69 0.08
30 INT134838 TGFB1 Positive_regulation of SMAD7 1 0.52 0.79 0.08
31 INT311915 Tgfbr1 Negative_regulation of Gene_expression of Mmp13 1 0.09 0.27 0.06
32 INT311910 Acvrl1 Positive_regulation of Phosphorylation of Smad1 1 0.12 0.24 0.06
33 INT311906 Binding of Smad4 and Insrr 1 0.00 0.18 0.06
34 INT353284 Prdx2 Negative_regulation of Gene_expression of Smad2 1 0.16 0.07 0.05
35 INT353290 Binding of Smad2 and Smad4 1 0.20 0.08 0.04
36 INT353294 Binding of Smad2 and Smad3 1 0.15 0.08 0.04
37 INT353295 Binding of Smad3 and Smad4 1 0.17 0.08 0.04
38 INT353289 Prdx2 Negative_regulation of Positive_regulation of Smad2 1 0.18 0.17 0.04
39 INT353293 Prdx2 Negative_regulation of Localization of Smad2 1 0.16 0 0.04
40 INT311909 Gene_expression of Smad6 Negative_regulation of Gene_expression of Col10a1 1 0.02 0.54 0.04
41 INT270950 Binding of Slc6a3 and Tgfb1i1 1 0.02 0.23 0.04
42 INT353287 Prdx2 Positive_regulation of Phosphorylation of Smad7 1 0.22 0.06 0.03
43 INT311904 Smad2 Positive_regulation of Gene_expression of Smad1 1 0.13 0.44 0.03
44 INT319218 Bmpr2 Negative_regulation of Smad2 1 0.17 0.12 0.03
45 INT265347 Binding of Ocln and Tgfbr1 1 0.18 0.06 0.03
46 INT265345 Binding of Tgfbr1 and Tjp1 1 0.09 0.06 0.03
47 INT353291 Prdx2 Positive_regulation of Smad7 1 0.31 0.06 0.03
48 INT353286 Prdx2 Positive_regulation of Phosphorylation of Smad2 1 0.24 0.06 0.03
49 INT280263 Binding of Smad4 and Proc 1 0.00 1.26 0.03
50 INT319219 Bmpr2 Positive_regulation of Smad1 1 0.18 0.29 0.03
51 INT319217 Bmpr2 Positive_regulation of Gene_expression of Smad1 1 0.19 0.11 0.03
52 INT353288 Smad7 Negative_regulation of Phosphorylation of Tgif1 1 0.08 0.06 0.03
53 INT265343 Positive_regulation of Binding of Tgfbr1 and Tjp1 1 0.12 0.06 0.03
54 INT265348 Positive_regulation of Binding of Ocln and Tgfbr1 1 0.25 0.06 0.03
55 INT120077 Gene_expression of Smad7 Negative_regulation of Positive_regulation of Itk 1 0.02 0.27 0
56 INT277927 WIF1 Negative_regulation of SMAD4 1 0.23 0.37 0
57 INT269915 Binding of Smad2 and Sox17 1 0.21 0.07 0
58 INT285666 PPARA Positive_regulation of TGFB1I1 1 0.15 0.82 0
59 INT265231 Binding of FKBP1A and TGFBR1 1 0.11 0.35 0
60 INT355603 Binding of CTNNA1 and Ctnnb1 1 0.00 1.07 0
61 INT220818 Binding of Ctnnb1 and Myc 1 0.06 0.13 0
62 INT218669 Olr811 Negative_regulation of Phosphorylation of Smad2 1 0.01 0.18 0
63 INT218663 Olr811 Positive_regulation of Gene_expression of Smad7 1 0.01 0.45 0
64 INT286566 Binding of Ctnnb1 and Cdh6 1 0.00 1 0
65 INT337915 Tgfbr1 Positive_regulation of Negative_regulation of Smad2 1 0.05 0.15 0
66 INT265344 sb Negative_regulation of Tgfbr1 1 0.00 0.06 0
67 INT286562 Gene_expression of Pkd1 Positive_regulation of Ctnnb1 1 0.02 0.52 0
68 INT251072 Wnt3a Positive_regulation of Axin2 1 0.23 0.29 0
69 INT136693 Gtf3a Positive_regulation of Ctnnb1 1 0.05 0 0
70 INT134836 Binding of SMAD7 and YAP1 1 0.53 0.89 0
71 INT107434 Negative_regulation of Tgfb1i1 Positive_regulation of Cxcl2 1 0.01 0 0
72 INT287885 Binding of DVL1 and AXIN1 1 0.02 0 0
73 INT329746 ENG Positive_regulation of SMAD1 1 0.15 0.44 0
74 INT269936 Smad2 Positive_regulation of Cdkn2b 1 0.15 0.07 0
75 INT310188 Binding of Adcyap1r1 and Smad7 1 0.00 0 0
76 INT347155 Mirlet7a-1 Negative_regulation of Smad7 1 0.10 0 0
77 INT268341 SMAD2 Positive_regulation of SMAD4 1 0.31 0.56 0
78 INT236724 Binding of AXIN1 and Ctnnd2 1 0.39 1.03 0
79 INT283361 AXIN2 Negative_regulation of GSK 1 0.09 1.67 0
80 INT337914 sb Negative_regulation of Phosphorylation of Smad2 1 0.00 0.13 0
81 INT220821 Binding of MAX and Ctnnb1 1 0.09 0.13 0
82 INT107438 Tgfb1i1 Positive_regulation of Tnf 1 0.00 0 0
83 INT107435 Tgfb1i1 Positive_regulation of Gene_expression of Tnf 1 0.00 0 0
84 INT286561 Binding of Ctnnb1 and Cdh2 1 0.00 1.06 0
85 INT246797 Tgfb1i1 Positive_regulation of Phosphorylation of Tsc2 1 0.01 0.66 0
86 INT347123 Binding of Axin2 and Lrp1 1 0.08 0.2 0
87 INT286567 Prkd1 Regulation of Ctnnb1 1 0.01 0.39 0
88 INT337918 sb Positive_regulation of Negative_regulation of Smad2 1 0.00 0.15 0
89 INT310190 Binding of Adcyap1r1 and Smad6 1 0.00 0 0
90 INT310192 Tgfbr1 Positive_regulation of Regulation of Acvrl1 1 0.01 0 0
91 INT283362 AXIN2 Negative_regulation of APC 1 0.10 1.67 0
92 INT218670 Olr811 Regulation of Phosphorylation of Smad2 1 0.00 0.33 0
93 INT246785 Tgfb1i1 Positive_regulation of Positive_regulation of Akt1 1 0.01 0.66 0
94 INT269938 Smad2 Positive_regulation of Tpt1 1 0.14 0.07 0
95 INT107437 Tgfb1i1 Positive_regulation of Cxcl2 1 0.01 0 0
96 INT268344 SMAD3 Positive_regulation of SMAD4 1 0.17 0.56 0
97 INT172981 PAN3 Negative_regulation of SMAD4 1 0.01 0.98 0
98 INT337917 Binding of sb and Tgfbr1 1 0.00 1.06 0
99 INT286572 Binding of Ctnnb1 and Pkd1 1 0.02 0.96 0
100 INT107436 Tgfb1i1 Positive_regulation of Gene_expression of Cxcl2 1 0.01 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for I-SMAD binding. They are ordered first by their pain relevance and then by number of times they were reported in I-SMAD binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT127112 Phosphorylation of Smad2 19 0.80 11.01 5.36
2 INT120072 Gene_expression of Smad7 38 0.74 20.87 3.69
3 INT75484 Gene_expression of Tgfbr1 21 0.64 13.36 3.15
4 INT101567 Gene_expression of Ctnnb1 7 0.64 10.11 2.89
5 INT127113 Positive_regulation of Phosphorylation of Smad2 1 0.68 2.38 2.51
6 INT194504 Gene_expression of Smad2 27 0.65 7.45 2.25
7 INT81641 Gene_expression of Ctnnb1 23 0.72 14.93 1.97
8 INT107178 Gene_expression of Smad4 12 0.65 9.85 1.92
9 INT174924 Gene_expression of Smad7 6 0.41 3.59 1.76
10 INT174923 Positive_regulation of Gene_expression of Smad7 3 0.37 2.3 1.73
11 INT123990 Positive_regulation of Ctnnb1 8 0.43 2.85 1.63
12 INT99391 Localization of Ctnnb1 7 0.80 5.84 1.61
13 INT127115 Regulation of Phosphorylation of Smad2 1 0.60 1.74 1.53
14 INT255251 Negative_regulation of Smad2 12 0.32 5.69 1.44
15 INT129619 Phosphorylation of Smad2 34 0.61 11.6 1.34
16 INT120076 Positive_regulation of Gene_expression of Smad7 16 0.65 11.33 1.25
17 INT99389 Negative_regulation of Ctnnb1 8 0.45 3.97 1.21
18 INT310164 Negative_regulation of Gene_expression of Tgfbr1 9 0.40 6.11 1.17
19 INT101570 Positive_regulation of Gene_expression of Ctnnb1 1 0.58 5.7 1.07
20 INT218696 Negative_regulation of Phosphorylation of Smad2 3 0.42 4.36 0.92
21 INT101566 Negative_regulation of Gene_expression of Ctnnb1 1 0.35 2.28 0.88
22 INT265313 Positive_regulation of Tgfbr1 8 0.66 2.95 0.87
23 INT267095 Regulation of Gene_expression of Smad2 3 0.44 1.77 0.8
24 INT161947 Positive_regulation of TGFBR1 2 0.52 1.6 0.76
25 INT137007 Gene_expression of SMAD2 6 0.75 2.53 0.75
26 INT265318 Negative_regulation of Gene_expression of Smad2 8 0.26 2.16 0.72
27 INT272878 Negative_regulation of Smad7 4 0.41 3.86 0.72
28 INT172960 Negative_regulation of Gene_expression of Smad4 7 0.39 5.88 0.71
29 INT269896 Positive_regulation of Gene_expression of Smad2 9 0.40 2.15 0.69
30 INT137009 Negative_regulation of Gene_expression of SMAD2 4 0.42 1.76 0.66
31 INT268377 Phosphorylation of SMAD2 7 0.80 0.85 0.65
32 INT99390 Regulation of Ctnnb1 4 0.62 3.12 0.64
33 INT302664 Positive_regulation of SMAD2 2 0.49 0.85 0.64
34 INT144922 Gene_expression of TGFBR1 4 0.72 0.19 0.57
35 INT103781 Negative_regulation of Smad4 9 0.42 4.42 0.54
36 INT76960 Negative_regulation of Ctnnb1 5 0.57 3.46 0.53
37 INT158889 Gene_expression of Smad2 5 0.65 1.25 0.51
38 INT120074 Regulation of Gene_expression of Smad7 1 0.58 2.05 0.5
39 INT267837 Gene_expression of TGFB1I1 1 0.15 1.38 0.48
40 INT81645 Positive_regulation of Gene_expression of Ctnnb1 6 0.63 3.78 0.47
41 INT210125 Regulation of Axin1 1 0.02 2.45 0.46
42 INT71019 Negative_regulation of SMAD4 12 0.42 6.88 0.43
43 INT224538 Negative_regulation of Gene_expression of Smad7 1 0.09 0.25 0.43
44 INT76958 Positive_regulation of Ctnnb1 14 0.64 5.48 0.41
45 INT285501 Gene_expression of Smad1 6 0.42 3.09 0.41
46 INT95872 Localization of Ctnnb1 7 0.74 2.75 0.4
47 INT292484 Negative_regulation of TGFBR1 3 0.19 0.75 0.39
48 INT311882 Negative_regulation of Smad1 1 0.25 0.99 0.39
49 INT117564 Gene_expression of SMAD4 12 0.71 8.7 0.37
50 INT81644 Regulation of Ctnnb1 5 0.41 3.38 0.37
51 INT81643 Regulation of Gene_expression of Ctnnb1 3 0.57 1.5 0.37
52 INT254816 Negative_regulation of Tgfbr1 20 0.55 9.24 0.34
53 INT108324 Negative_regulation of Gene_expression of Ctnnb1 1 0.06 1.43 0.31
54 INT134840 Gene_expression of SMAD7 1 0.74 2.74 0.31
55 INT92100 Binding of Smad4 5 0.31 2.23 0.3
56 INT129908 Positive_regulation of Smad2 5 0.45 2.13 0.3
57 INT137008 Positive_regulation of Gene_expression of SMAD2 2 0.49 0.51 0.3
58 INT184716 Binding of Smad7 2 0.34 0.91 0.29
59 INT224877 Positive_regulation of Gene_expression of Smad2 1 0.12 0.16 0.29
60 INT311881 Regulation of Positive_regulation of Tgfbr1 1 0.22 0.97 0.29
61 INT272890 Regulation of Negative_regulation of Smad7 1 0.19 1.33 0.29
62 INT172978 Negative_regulation of SMAD2 4 0.42 0.89 0.27
63 INT151719 Negative_regulation of Positive_regulation of Ctnnb1 1 0.23 1.9 0.24
64 INT228793 Negative_regulation of Gene_expression of Smad7 5 0.25 2.33 0.23
65 INT129907 Regulation of Smad2 1 0.40 0.87 0.23
66 INT265311 Localization of Smad2 5 0.50 1.57 0.21
67 INT265334 Regulation of Phosphorylation of Smad2 2 0.17 0.96 0.2
68 INT272889 Negative_regulation of Smad6 2 0.20 1.31 0.19
69 INT311886 Phosphorylation of Tgfbr1 1 0.40 0.7 0.19
70 INT311891 Phosphorylation of Smad1 4 0.51 1.34 0.18
71 INT277935 Binding of SMAD4 4 0.28 1.12 0.17
72 INT268365 Binding of SMAD2 2 0.47 0.56 0.17
73 INT99392 Negative_regulation of Localization of Ctnnb1 2 0.59 1.43 0.17
74 INT151721 Negative_regulation of Localization of Ctnnb1 1 0.23 0.96 0.17
75 INT325506 Positive_regulation of Localization of Ctnnb1 1 0.05 0.28 0.17
76 INT210123 Localization of Axin1 1 0.04 0.84 0.17
77 INT66933 Binding of AXIN1 6 0.32 1.8 0.16
78 INT228790 Positive_regulation of Smad7 4 0.41 0.58 0.15
79 INT139977 Regulation of Smad4 1 0.16 1.41 0.15
80 INT310174 Positive_regulation of Smad1 9 0.45 2.16 0.14
81 INT263410 Negative_regulation of Axin1 1 0.01 0 0.14
82 INT135490 Localization of Smad2 1 0.51 0.08 0.14
83 INT302662 Negative_regulation of Negative_regulation of TGFBR1 1 0.14 0 0.13
84 INT158893 Negative_regulation of Gene_expression of Smad2 1 0.30 0.13 0.13
85 INT130374 Transcription of Ctnnb1 1 0.19 0 0.13
86 INT129616 Negative_regulation of Phosphorylation of Smad2 4 0.38 0.78 0.12
87 INT311892 Regulation of Positive_regulation of Smad2 1 0.23 0.24 0.12
88 INT254819 Regulation of Negative_regulation of Tgfbr1 1 0.15 1.2 0.09
89 INT325505 Transcription of Smad2 1 0.67 0.16 0.09
90 INT325510 Transcription of Smad4 1 0.67 0.16 0.09
91 INT294014 Regulation of AXIN1 3 0.24 1.04 0.08
92 INT145364 Negative_regulation of AXIN1 2 0.33 0.52 0.08
93 INT353267 Negative_regulation of Positive_regulation of Smad7 1 0.25 0.32 0.08
94 INT311885 Positive_regulation of Gene_expression of Tgfbr1 2 0.44 0.35 0.06
95 INT254790 Localization of Smad4 2 0.37 0.54 0.06
96 INT325665 Positive_regulation of Axin2 1 0.36 0.59 0.06
97 INT347118 Binding of Axin2 1 0.32 1.63 0.06
98 INT347149 Localization of Smad7 1 0.67 0 0.05
99 INT244699 Positive_regulation of AXIN1 1 0.02 0 0.05
100 INT254814 Positive_regulation of Phosphorylation of Smad2 7 0.33 3.74 0.04
101 INT337908 Binding of Smad2 3 0.24 1.06 0.04
102 INT311890 Binding of Smad1 2 0.23 0.46 0.04
103 INT172971 Gene_expression of Smad6 2 0.37 1.77 0.04
104 INT325670 Negative_regulation of Axin2 1 0.31 0.34 0.04
105 INT311898 Positive_regulation of Gene_expression of Smad6 1 0.33 0.53 0.04
106 INT353261 Negative_regulation of Localization of Smad2 1 0.33 0 0.04
107 INT270964 Binding of Tgfb1i1 1 0.02 0.23 0.04
108 INT334291 Positive_regulation of Gene_expression of SMAD4 1 0.18 0 0.04
109 INT325666 Regulation of Axin2 1 0.32 0.31 0.04
110 INT353263 Positive_regulation of Localization of Smad2 1 0.33 0.15 0.04
111 INT325669 Gene_expression of Axin2 4 0.57 1.42 0.03
112 INT268360 Positive_regulation of SMAD4 3 0.55 1.55 0.03
113 INT254799 Transcription of Smad2 1 0.19 0.52 0.03
114 INT353266 Negative_regulation of Negative_regulation of Smad2 1 0.28 0 0.03
115 INT296618 Negative_regulation of Smad2 1 0.37 1.42 0.03
116 INT350515 Transcription of SMAD7 1 0.07 0.38 0.03
117 INT353280 Phosphorylation of Smad7 1 0.48 0.06 0.03
118 INT311888 Negative_regulation of Phosphorylation of Smad1 1 0.25 0.48 0.03
119 INT117563 Negative_regulation of Gene_expression of SMAD4 6 0.54 3.87 0
120 INT268378 Positive_regulation of Phosphorylation of SMAD2 3 0.67 1.22 0
121 INT271411 Positive_regulation of Positive_regulation of Smad2 2 0.45 0.9 0
122 INT76959 Binding of Ctnnb1 2 0.34 0.69 0
123 INT334327 Regulation of SMAD4 2 0.35 1.73 0
124 INT265316 Binding of Tgfbr1 2 0.35 0.59 0
125 INT294025 Phosphorylation of AXIN1 2 0.38 0.47 0
126 INT265326 Regulation of Tgfbr1 2 0.43 0.17 0
127 INT205099 Positive_regulation of Gene_expression of AXIN2 1 0.48 3.48 0
128 INT268368 Transcription of SMAD4 1 0.54 1.7 0
129 INT329771 Positive_regulation of SMAD1 1 0.36 2.3 0
130 INT285684 Positive_regulation of Transcription of TGFB1I1 1 0.11 0.41 0
131 INT230651 Phosphorylation of Ctnnb1 1 0.10 0 0
132 INT230674 Positive_regulation of Phosphorylation of Ctnnb1 1 0.06 0 0
133 INT326137 Protein_catabolism of Ctnnb1 1 0.02 1.08 0
134 INT315214 Negative_regulation of Regulation of Tgfbr1 1 0.41 0 0
135 INT287932 Negative_regulation of Binding of AXIN1 1 0.12 0 0
136 INT179300 Negative_regulation of TGFB1I1 1 0.06 1.92 0
137 INT347148 Regulation of Smad7 1 0.26 0 0
138 INT329780 Negative_regulation of Positive_regulation of SMAD1 1 0.22 0.51 0
139 INT268388 Positive_regulation of Positive_regulation of TGFBR1 1 0.35 0.61 0
140 INT355576 Negative_regulation of Negative_regulation of Ctnnb1 1 0.02 1.14 0
141 INT296615 Positive_regulation of Smad2 1 0.50 1.51 0
142 INT173000 Negative_regulation of Localization of SMAD4 1 0.22 0.98 0
143 INT173008 Localization of SMAD4 1 0.38 0.97 0
144 INT218701 Negative_regulation of Binding of Smad7 1 0.14 0.15 0
145 INT205105 Gene_expression of AXIN2 1 0.74 6.6 0
146 INT166121 Binding of SMAD7 1 0.30 0.39 0
147 INT220769 Positive_regulation of Positive_regulation of Ctnnb1 1 0.10 0 0
148 INT353273 Negative_regulation of Phosphorylation of Smad7 1 0.25 0 0
149 INT246775 Positive_regulation of Tgfb1i1 1 0.01 0.21 0
150 INT272228 Localization of TGFBR1 1 0.34 0.74 0
151 INT347145 Transcription of Smad7 1 0.68 0 0
152 INT334289 Regulation of Binding of SMAD4 1 0.16 0 0
153 INT265319 Positive_regulation of Negative_regulation of Tgfbr1 1 0.47 0.53 0
154 INT334288 Regulation of Negative_regulation of SMAD4 1 0.16 0 0
155 INT144920 Positive_regulation of Gene_expression of TGFBR1 1 0.65 0 0
156 INT285682 Transcription of TGFB1I1 1 0.15 0.4 0
157 INT349907 Negative_regulation of Gene_expression of Axin2 1 0.32 0 0
158 INT228250 Positive_regulation of Smad4 1 0.45 1.93 0
159 INT295579 Negative_regulation of Phosphorylation of SMAD2 1 0.42 0.08 0
160 INT310176 Localization of Tgfbr1 1 0.11 0.83 0
161 INT145371 Negative_regulation of AXIN2 1 0.34 0 0
162 INT218685 Binding of Smad7 1 0.13 0.15 0
163 INT251046 Localization of Axin2 1 0.53 0 0
164 INT310179 Positive_regulation of Positive_regulation of Tgfbr1 1 0.08 0 0
165 INT310173 Binding of Smad6 1 0.05 0 0
166 INT287935 Positive_regulation of Binding of AXIN1 1 0.14 0 0
167 INT228247 Regulation of Positive_regulation of Smad4 1 0.26 0.97 0
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