GO:0070419

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Name nonhomologous end joining complex
Categary Component
Go Slim No
Go Link GO:0070419
Unique Molecular Interactions 38
Total Molecular Interactions 66
Total Single Events 143
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for nonhomologous end joining complex. They are ordered first by their pain relevance and then by number of times they were reported for nonhomologous end joining complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT322266 Binding of LIG4 and NOS3 1 0.02 2.35 0.82
2 INT117412 RYBP Negative_regulation of LIG4 1 0.00 0.42 0.76
3 INT322048 Prkdc Negative_regulation of Col7a1 1 0.00 0.45 0.5
4 INT125514 Positive_regulation of PRKDC Positive_regulation of Positive_regulation of NFKB1 1 0.07 0.44 0.26
5 INT309513 Binding of Xrcc6 and Htt 1 0.30 3.69 0.21
6 INT350736 PRKDC Negative_regulation of CA2 1 0.02 0.16 0.11
7 INT350735 PRKDC Negative_regulation of ITPR3 1 0.01 0.16 0.11
8 INT309511 Binding of Xrcc6 and Xrcc5 1 0.18 1.18 0.08
9 INT249201 PRKDC Regulation of Regulation of CYBB 1 0.01 0.09 0.05
10 INT352669 PRKDC Positive_regulation of Memor1 1 0.00 1.02 0.04
11 INT306511 Binding of XRCC6 and Ung 1 0.00 0.78 0
12 INT249169 PMAIP1 Positive_regulation of PRKDC 1 0.00 0 0
13 INT284919 XRCC6 Negative_regulation of BAX 1 0.01 0.64 0
14 INT309515 Xrcc6 Regulation of Gene_expression of Htt 1 0.32 0.08 0
15 INT225593 Ncoa6 Positive_regulation of Prkdc 1 0.02 0 0
16 INT306509 Binding of XRCC6 and Clu 1 0.37 0.27 0
17 INT225480 Binding of Prkdc and Acsl1 1 0.00 0 0
18 INT276904 Regulation of Binding of Egfr and Prkdc 1 0.03 0.42 0
19 INT225613 TARBP2 Positive_regulation of Prkdc 1 0.00 0 0
20 INT225642 Binding of XRCC5 and Acsl1 1 0.01 0 0
21 INT309521 PRKDC Regulation of Gene_expression of Htt 1 0.41 0.08 0
22 INT309517 Binding of Bax and Xrcc6 1 0.15 0.5 0
23 INT309519 Xrcc5 Regulation of Gene_expression of Htt 1 0.18 0.08 0
24 INT253014 Binding of XRCC5 and Zic2 1 0.00 0.14 0
25 INT309512 Negative_regulation of Xrcc6 Positive_regulation of Phosphorylation of Gopc 1 0.20 0.17 0
26 INT276905 Binding of Egfr and Prkdc 1 0.04 0.41 0
27 INT225614 Binding of XRCC5 and Parp1 1 0.09 0 0
28 INT252904 Binding of PRKDC and XRCC5 1 0.00 0.14 0
29 INT253013 Binding of PRKDC and Zic2 1 0.00 0.14 0
30 INT309518 Negative_regulation of Binding of Bax and Xrcc6 1 0.16 0.25 0
31 INT323185 Binding of LIG4 and OGG1 1 0.02 0.32 0
32 INT309516 Htt Positive_regulation of Gene_expression of Xrcc6 1 0.49 0.06 0
33 INT309509 Negative_regulation of Binding of Xrcc6 and Htt 1 0.31 0.41 0
34 INT309510 Htt Regulation of Gene_expression of Xrcc6 1 0.19 0.15 0
35 INT309508 Htt Negative_regulation of Binding of Xrcc6 1 0.31 0.48 0
36 INT309514 Positive_regulation of Binding of Xrcc6 and Htt 1 0.33 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for nonhomologous end joining complex. They are ordered first by their pain relevance and then by number of times they were reported in nonhomologous end joining complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT108148 Positive_regulation of Prkdc 2 0.16 0.49 2.31
2 INT117415 Negative_regulation of LIG4 4 0.04 1.59 2.17
3 INT118155 Regulation of Positive_regulation of Prkdc 1 0.10 0.49 1.42
4 INT125525 Positive_regulation of PRKDC 7 0.45 2.72 1.21
5 INT166935 Gene_expression of Prkdc 10 0.65 3.14 0.9
6 INT125526 Gene_expression of PRKDC 5 0.58 4 0.74
7 INT333877 Protein_catabolism of LIG4 2 0.03 2.03 0.57
8 INT309465 Gene_expression of Xrcc6 24 0.59 5.49 0.43
9 INT125524 Positive_regulation of Gene_expression of PRKDC 2 0.09 1 0.29
10 INT180393 Positive_regulation of Gene_expression of Prkdc 3 0.49 1.17 0.26
11 INT327888 Localization of Prkdc 1 0.14 1.11 0.23
12 INT309493 Binding of Xrcc6 1 0.37 3 0.2
13 INT142384 Gene_expression of XRCC6 3 0.58 1.98 0.16
14 INT309492 Positive_regulation of Gene_expression of Xrcc6 1 0.38 1.29 0.13
15 INT290726 Binding of Prkdc 1 0.03 1.05 0.13
16 INT352666 Regulation of PRKDC 1 0.01 0.36 0.09
17 INT249260 Positive_regulation of Phosphorylation of PRKDC 1 0.03 0.06 0.08
18 INT309460 Binding of Xrcc5 1 0.16 0.09 0.08
19 INT249280 Phosphorylation of PRKDC 2 0.13 0.3 0.07
20 INT309478 Regulation of Gene_expression of Xrcc6 1 0.21 0.36 0.07
21 INT352653 Positive_regulation of Positive_regulation of PRKDC 1 0.01 0.56 0.03
22 INT180394 Phosphorylation of Prkdc 2 0.07 0.6 0
23 INT284963 Binding of XRCC6 2 0.36 1.57 0
24 INT309463 Regulation of Negative_regulation of Xrcc6 1 0.18 0.15 0
25 INT309499 Localization of Xrcc6 1 0.57 0.13 0
26 INT352658 Negative_regulation of PRKDC 1 0.01 0.33 0
27 INT309491 Negative_regulation of Gene_expression of Xrcc6 1 0.32 0.56 0
28 INT350511 Negative_regulation of XRCC6 1 0.08 0.58 0
29 INT309475 Positive_regulation of Binding of Xrcc6 1 0.53 0 0
30 INT309464 Negative_regulation of Negative_regulation of Xrcc6 1 0.45 0.09 0
31 INT309472 Protein_catabolism of Xrcc6 1 0.67 0.43 0
32 INT309468 Transcription of Xrcc6 1 0.52 0.24 0
33 INT350522 Positive_regulation of Gene_expression of XRCC6 1 0.11 0.53 0
34 INT348467 Positive_regulation of XRCC5 1 0.25 0.43 0
35 INT309467 Gene_expression of Xrcc5 1 0.26 0.1 0
36 INT309483 Positive_regulation of Xrcc5 1 0.20 0.1 0
37 INT309461 Negative_regulation of Xrcc6 1 0.45 0.92 0
38 INT309476 Positive_regulation of Protein_catabolism of Xrcc6 1 0.38 0.43 0
39 INT309502 Positive_regulation of Xrcc6 1 0.38 1.58 0
40 INT309479 Negative_regulation of Binding of Xrcc6 1 0.28 0.25 0
41 INT309488 Negative_regulation of Localization of Xrcc6 1 0.32 0.13 0
42 INT309503 Phosphorylation of Xrcc6 1 0.54 0.55 0
43 INT323201 Binding of LIG4 1 0.03 0.32 0
44 INT225463 Binding of XRCC5 1 0.36 0 0
45 INT309480 Positive_regulation of Negative_regulation of Xrcc6 1 0.38 0.12 0
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