GO:0070427

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Name nucleotide-binding oligomerization domain containing 1 signaling pathway
Categary Process
Go Slim No
Go Link GO:0070427
Unique Molecular Interactions 57
Total Molecular Interactions 66
Total Single Events 602
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for nucleotide-binding oligomerization domain containing 1 signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for nucleotide-binding oligomerization domain containing 1 signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT131257 ITIH4 Positive_regulation of Gene_expression of Nfkbia 1 0.23 1.41 2.3
2 INT63918 Binding of Cck and Ripk2 1 0.28 0 2.07
3 INT131256 Positive_regulation of Nfkb1 Positive_regulation of Gene_expression of Nfkbia 1 0.38 0.94 1.31
4 INT129034 Nfkbia Positive_regulation of Nfkb1 1 0.02 0.67 0.89
5 INT134311 Tnf Positive_regulation of Protein_catabolism of Nfkbia 1 0.18 0.57 0.88
6 INT153123 NFKBIA Negative_regulation of Phosphorylation of RELA 1 0.03 2.01 0.71
7 INT125543 Arsa Negative_regulation of Phosphorylation of Nfkbia 1 0.00 0.52 0.68
8 INT233669 gr Positive_regulation of Transcription of Nfkbia 1 0.26 0.33 0.64
9 INT87934 Phosphorylation of Nfkbia Positive_regulation of Nfkb1 1 0.02 0.1 0.45
10 INT87936 Nfkbia Positive_regulation of Nfkb1 1 0.03 0.1 0.44
11 INT207113 Nfkbia Negative_regulation of Nfkb1 1 0.11 0.96 0.4
12 INT4382 RIPK2 Regulation of INS 1 0.12 0.58 0.36
13 INT4381 RIPK2 Positive_regulation of Localization of INS 1 0.13 0.53 0.34
14 INT108879 Negative_regulation of PTGS2 Positive_regulation of Protein_catabolism of Nfkbia 1 0.00 0.43 0.31
15 INT285564 Binding of IL1B and Ripk2 1 0.04 0.76 0.31
16 INT143724 Binding of Ikbkg and Nfkbia 1 0.02 0.79 0.29
17 INT143723 Positive_regulation of Binding of Ikbkg and Nfkbia 1 0.02 0.8 0.29
18 INT80873 Positive_regulation of Nfkb1 Positive_regulation of Protein_catabolism of Nfkbia 2 0.01 0.58 0.27
19 INT108878 ZNF236 Regulation of Protein_catabolism of Nfkbia 1 0.00 0.38 0.26
20 INT108880 ZNF236 Regulation of Gene_expression of Nfkbia 1 0.00 0.38 0.26
21 INT108877 ZNF236 Regulation of Phosphorylation of Nfkbia 1 0.00 0.38 0.26
22 INT108881 ZNF236 Regulation of Transcription of Nfkbia 1 0.00 0.36 0.26
23 INT144241 CGA Negative_regulation of Phosphorylation of NFKBIA 1 0.10 0.34 0.22
24 INT144244 TNF Positive_regulation of Protein_catabolism of NFKBIA 1 0.28 0.34 0.22
25 INT144253 TNF Positive_regulation of Phosphorylation of NFKBIA 1 0.39 0.34 0.22
26 INT144247 CGA Positive_regulation of Protein_catabolism of NFKBIA 1 0.11 0.34 0.22
27 INT144243 CGA Positive_regulation of Phosphorylation of NFKBIA 1 0.11 0.34 0.22
28 INT55252 Binding of CCK and RIPK2 1 0.40 0 0.2
29 INT159788 Tnf Positive_regulation of Phosphorylation of Nfkbia 1 0.01 0.39 0.19
30 INT279267 Binding of RIPK2 and Positive_regulation of Gene_expression of CASP1 1 0.26 1.12 0.14
31 INT139790 PRSS53 Negative_regulation of Phosphorylation of NFKBIA 1 0.01 0.9 0.11
32 INT306265 Binding of NFKB1 and NFKBIA 1 0.21 0.48 0.11
33 INT139789 TNFAIP8 Positive_regulation of Phosphorylation of NFKBIA 1 0.02 0.89 0.11
34 INT139788 TNFAIP8 Positive_regulation of NFKBIA 1 0.01 0.88 0.11
35 INT263449 Binding of NFKBIA and TBK1 1 0.07 0.2 0.1
36 INT263450 NFKB2 Positive_regulation of Protein_catabolism of NFKBIA 1 0.17 0.17 0.09
37 INT201766 Binding of RIPK2 and Ngfr 1 0.02 0.41 0.04
38 INT161532 Tlr4 Positive_regulation of Protein_catabolism of Nfkbia 1 0.00 0.76 0.03
39 INT161531 Nfkbia Regulation of Gene_expression of Tlr4 1 0.01 0.75 0.03
40 INT161534 Tlr4 Positive_regulation of Phosphorylation of Nfkbia 1 0.00 0.77 0.03
41 INT164909 IL33 Positive_regulation of Phosphorylation of NFKBIA 1 0.53 0.05 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for nucleotide-binding oligomerization domain containing 1 signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in nucleotide-binding oligomerization domain containing 1 signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT81538 Phosphorylation of Nfkbia 27 0.62 8.86 10.49
2 INT80872 Protein_catabolism of Nfkbia 28 0.92 10.56 8.62
3 INT95297 Gene_expression of Nfkbia 14 0.68 7.61 8.24
4 INT38503 Positive_regulation of Ripk2 11 0.67 2.9 7.47
5 INT81532 Negative_regulation of Protein_catabolism of Nfkbia 21 0.54 8.92 7.38
6 INT93481 Negative_regulation of Protein_catabolism of Nfkbia 14 0.39 7.24 7.21
7 INT88498 Protein_catabolism of Nfkbia 14 0.82 6.94 7.1
8 INT81541 Negative_regulation of Nfkbia 12 0.51 5.73 6.79
9 INT47976 Protein_catabolism of NFKBIA 17 0.88 7.57 5.79
10 INT81535 Negative_regulation of Phosphorylation of Nfkbia 15 0.44 5.74 5.18
11 INT143234 Gene_expression of Nfkbia 10 0.62 5.2 5.02
12 INT37976 Binding of Ripk2 6 0.47 0.27 5.01
13 INT88496 Positive_regulation of Protein_catabolism of Nfkbia 8 0.53 3.05 4.78
14 INT131253 Positive_regulation of Gene_expression of Nfkbia 4 0.41 3.28 4.71
15 INT20459 Regulation of Ripk2 5 0.44 0 4.53
16 INT87210 Positive_regulation of Nfkbia 9 0.61 3.89 4.35
17 INT81543 Positive_regulation of Phosphorylation of Nfkbia 7 0.37 2.51 4.1
18 INT108868 Transcription of Nfkbia 2 0.57 2.91 4.03
19 INT6025 Negative_regulation of RIPK2 4 0.57 0.96 2.82
20 INT19421 Positive_regulation of RIPK2 6 0.49 5.63 2.72
21 INT233606 Transcription of Nfkbia 1 0.66 1.55 2.71
22 INT93401 Positive_regulation of Protein_catabolism of Nfkbia 11 0.46 3.89 2.7
23 INT107968 Positive_regulation of NFKBIA 9 0.46 5.27 2.69
24 INT47974 Negative_regulation of Protein_catabolism of NFKBIA 7 0.49 2.38 2.69
25 INT61004 Negative_regulation of Regulation of Ripk2 1 0.41 0 2.68
26 INT108869 Localization of Nfkbia 5 0.56 1.04 2.63
27 INT122003 Phosphorylation of NFKBIA 9 0.59 5.44 2.51
28 INT37977 Negative_regulation of Ripk2 3 0.42 0.92 2.03
29 INT129318 Negative_regulation of NFKBIA 10 0.38 6.19 2.02
30 INT26317 Gene_expression of NFKBIA 5 0.45 2.97 1.96
31 INT56080 Transcription of NFKBIA 2 0.40 2.16 1.93
32 INT151269 Positive_regulation of Localization of Nfkbia 1 0.37 0 1.86
33 INT37978 Localization of Ripk2 4 0.78 0.57 1.73
34 INT126236 Positive_regulation of Positive_regulation of NFKBIA 4 0.46 2.18 1.69
35 INT55511 Positive_regulation of Binding of Ripk2 1 0.49 0.19 1.69
36 INT47972 Positive_regulation of Protein_catabolism of NFKBIA 5 0.46 2.09 1.53
37 INT233612 Regulation of Transcription of Nfkbia 1 0.36 0.55 1.43
38 INT87215 Localization of Nfkbia 5 0.69 1.64 1.39
39 INT233638 Positive_regulation of Transcription of Nfkbia 1 0.56 1.01 1.33
40 INT131254 Positive_regulation of Transcription of Nfkbia 1 0.36 0.99 1.28
41 INT39144 Gene_expression of RIPK2 5 0.75 2.56 1.27
42 INT166013 Positive_regulation of Gene_expression of NFKBIA 2 0.32 1.15 1.2
43 INT38502 Gene_expression of Ripk2 3 0.65 0.17 1.16
44 INT129726 Regulation of Nfkbia 2 0.06 1.63 1.05
45 INT107971 Regulation of NFKBIA 3 0.24 2.03 1.04
46 INT81542 Regulation of Protein_catabolism of Nfkbia 2 0.04 0.43 1.02
47 INT143235 Positive_regulation of Gene_expression of Nfkbia 2 0.56 0.97 1.01
48 INT124198 Negative_regulation of Nfkbia 4 0.37 2.58 0.97
49 INT19422 Protein_catabolism of RIPK2 2 0.86 0.62 0.97
50 INT36850 Negative_regulation of Negative_regulation of RIPK2 1 0.57 0 0.97
51 INT81540 Positive_regulation of Nfkbia 4 0.22 1.37 0.92
52 INT38426 Regulation of RIPK2 3 0.60 0.62 0.91
53 INT42076 Regulation of Negative_regulation of RIPK2 1 0.44 0.91 0.91
54 INT143714 Phosphorylation of Nfkbia 4 0.64 2.94 0.87
55 INT55512 Positive_regulation of Localization of Ripk2 1 0.67 0.09 0.85
56 INT143720 Negative_regulation of Phosphorylation of Nfkbia 3 0.33 2.68 0.83
57 INT40227 Regulation of Positive_regulation of Ripk2 1 0.44 0 0.82
58 INT159548 Regulation of Protein_catabolism of Nfkbia 1 0.18 0.62 0.82
59 INT233630 Regulation of Nfkbia 1 0.42 0.27 0.76
60 INT233646 Regulation of Localization of Nfkbia 1 0.42 0.27 0.76
61 INT37975 Negative_regulation of Binding of Ripk2 1 0.57 0 0.75
62 INT95298 Negative_regulation of Gene_expression of Nfkbia 2 0.38 0.62 0.71
63 INT81533 Negative_regulation of Negative_regulation of Nfkbia 1 0.04 0.36 0.7
64 INT143719 Negative_regulation of Gene_expression of Nfkbia 2 0.43 1.31 0.68
65 INT166019 Regulation of Gene_expression of NFKBIA 1 0.05 0.64 0.65
66 INT122004 Negative_regulation of Phosphorylation of NFKBIA 3 0.41 1.59 0.58
67 INT263482 Positive_regulation of Transcription of NFKBIA 1 0.39 0.61 0.57
68 INT25362 Binding of NFKBIA 4 0.26 2.52 0.55
69 INT19420 Positive_regulation of Positive_regulation of RIPK2 1 0.49 0.59 0.5
70 INT38738 Localization of RIPK2 2 0.68 0.07 0.45
71 INT132627 Binding of Nfkbia 1 0.03 0.41 0.31
72 INT56079 Negative_regulation of Transcription of NFKBIA 1 0.05 0.54 0.26
73 INT108867 Regulation of Transcription of Nfkbia 1 0.00 0.36 0.25
74 INT151129 Negative_regulation of Localization of Nfkbia 1 0.30 0.31 0.19
75 INT201691 Binding of RIPK2 2 0.18 1.51 0.17
76 INT154558 Regulation of Phosphorylation of Nfkbia 1 0.00 0.33 0.17
77 INT87209 Negative_regulation of Positive_regulation of Nfkbia 1 0.31 0.15 0.16
78 INT87213 Positive_regulation of Localization of Nfkbia 1 0.34 0.15 0.16
79 INT240596 Negative_regulation of Gene_expression of RIPK2 1 0.06 0.91 0.15
80 INT136002 Positive_regulation of Gene_expression of RIPK2 1 0.67 0.52 0.15
81 INT139798 Positive_regulation of Phosphorylation of NFKBIA 1 0.04 0.88 0.11
82 INT144094 Negative_regulation of Localization of Ripk2 1 0.42 0.49 0.09
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