GO:0070507

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Name regulation of microtubule cytoskeleton organization
Categary Process
Go Slim No
Go Link GO:0070507
Unique Molecular Interactions 41
Total Molecular Interactions 50
Total Single Events 469
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of microtubule cytoskeleton organization. They are ordered first by their pain relevance and then by number of times they were reported for regulation of microtubule cytoskeleton organization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT273235 Binding of Cdk5 and Cdk5r1 1 0.24 6.06 0.46
2 INT340609 Bdnf Regulation of Gene_expression of Wnt3a 1 0.53 0.31 0.36
3 INT339645 Binding of Cdk5r1 and Ebi3 1 0.01 0.78 0.31
4 INT298996 Il18 Positive_regulation of Gene_expression of Cdk5r1 1 0.03 1.65 0.29
5 INT299011 Il18 Positive_regulation of Transcription of Cdk5r1 1 0.03 1.65 0.29
6 INT247949 Cdk5r1 Positive_regulation of Cdk5 1 0.26 1.12 0.28
7 INT273232 Negative_regulation of Binding of Cdk5 and Cdk5r1 1 0.28 3.16 0.23
8 INT326831 Cdk5r2 Positive_regulation of Binding of Cdk5r1 1 0.01 0.95 0.21
9 INT269446 Binding of EPHA3 and HHIP 1 0.01 0 0.2
10 INT221955 Binding of ELAVL1 and CDK5R1 1 0.01 0.93 0.19
11 INT306067 Binding of ADH5 and CYLD 1 0.02 3.13 0.19
12 INT221956 CDK5R1 Regulation of Positive_regulation of CDK5 1 0.21 0.62 0.19
13 INT164791 Cdk5r1 Positive_regulation of Cdk5 1 0.30 0.25 0.17
14 INT164790 Cdk5r1 Positive_regulation of Trib3 1 0.02 0.25 0.17
15 INT299001 Il18 Positive_regulation of Cdk5r1 1 0.03 0.36 0.17
16 INT340608 Binding of Creb1 and Wnt3a 1 0.30 0.24 0.14
17 INT221958 CDK5R1 Positive_regulation of Positive_regulation of CDK5 1 0.36 0.38 0.1
18 INT221959 Binding of CDK5 and CDK5R1 1 0.28 0.53 0.1
19 INT201748 Car2 Positive_regulation of Cdk5r1 1 0.00 0.67 0.09
20 INT247948 Positive_regulation of Cdk5r1 Positive_regulation of Cdk5 1 0.26 0.16 0.07
21 INT307223 CYLD Positive_regulation of Localization of BCL3 1 0.12 0.51 0.06
22 INT307226 CYLD Negative_regulation of Localization of BCL3 1 0.10 0.45 0.06
23 INT221952 UTS2R Regulation of Protein_catabolism of CDK5R1 1 0.10 0.3 0.04
24 INT326830 Cdk5r1 Positive_regulation of Positive_regulation of Cdk5 1 0.09 0.16 0.04
25 INT221953 UTS2R Positive_regulation of Gene_expression of CDK5R1 1 0.16 0.23 0.04
26 INT221962 UTS2R Regulation of Gene_expression of CDK5R1 1 0.09 0.43 0.03
27 INT221963 ELAVL1 Regulation of Gene_expression of CDK5R1 1 0.01 0.58 0.03
28 INT251072 Wnt3a Positive_regulation of Axin2 1 0.23 0.29 0
29 INT326893 Binding of Tcf4 and Wnt3a 1 0.13 0 0
30 INT307222 CYLD Regulation of Negative_regulation of BCL3 1 0.10 0.3 0
31 INT307225 CYLD Regulation of TNFRSF11A 1 0.14 0.81 0
32 INT326896 Wnt3a Positive_regulation of Transcription of PLD2 1 0.24 0.06 0
33 INT251070 Wnt3a Positive_regulation of Cldn3 1 0.30 0.29 0
34 INT326894 Wnt3a Positive_regulation of Transcription of Pld1 1 0.24 0.06 0
35 INT269562 GOPC Positive_regulation of Gene_expression of EPHA3 1 0.03 0 0
36 INT268446 Cdk5 Positive_regulation of Cdk5r1 1 0.02 0.58 0
37 INT266703 Binding of RYR1 and DIXDC1 1 0.26 0.1 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of microtubule cytoskeleton organization. They are ordered first by their pain relevance and then by number of times they were reported in regulation of microtubule cytoskeleton organization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT340600 Gene_expression of Wnt3a 1 0.68 2.14 9.14
2 INT60161 Gene_expression of EPHA3 43 0.75 3.66 6.25
3 INT134468 Gene_expression of Cdk5r1 26 0.48 27.09 5.2
4 INT109219 Negative_regulation of Cdk5r1 5 0.43 1.22 4.25
5 INT340603 Regulation of Gene_expression of Wnt3a 1 0.54 0.49 3.75
6 INT340595 Positive_regulation of Gene_expression of Wnt3a 1 0.61 0.86 3.11
7 INT201632 Positive_regulation of Cdk5r1 20 0.40 21.6 2.75
8 INT269377 Positive_regulation of EPHA3 22 0.18 0.97 2.55
9 INT101603 Positive_regulation of Cdk5r1 4 0.56 1.12 2.35
10 INT101599 Gene_expression of Cdk5r1 5 0.63 1.27 1.68
11 INT101601 Regulation of Cdk5r1 3 0.50 1.2 1.46
12 INT340596 Negative_regulation of Gene_expression of Wnt3a 1 0.51 0.38 1.4
13 INT114969 Gene_expression of CDK5R1 3 0.75 11.24 1.33
14 INT168312 Positive_regulation of Gene_expression of EPHA3 8 0.49 0.97 1.32
15 INT138783 Positive_regulation of Gene_expression of Cdk5r1 2 0.38 0.68 1.15
16 INT203890 Positive_regulation of Gene_expression of Cdk5r1 9 0.40 9.13 1.11
17 INT340604 Regulation of Wnt3a 1 0.24 0 0.95
18 INT109221 Positive_regulation of Negative_regulation of Cdk5r1 1 0.37 0.15 0.95
19 INT181177 Gene_expression of CYLD 5 0.69 24.96 0.89
20 INT269642 Binding of EPHA3 4 0.10 0.22 0.8
21 INT77663 Positive_regulation of CDK5R1 3 0.67 0.43 0.79
22 INT273220 Positive_regulation of Positive_regulation of Cdk5r1 4 0.40 5.3 0.75
23 INT134472 Binding of Cdk5r1 4 0.26 4.25 0.65
24 INT77662 Regulation of CDK5R1 2 0.60 1.93 0.63
25 INT221978 Regulation of Gene_expression of CDK5R1 1 0.59 5.08 0.61
26 INT273230 Negative_regulation of Cdk5r1 1 0.25 4.48 0.53
27 INT340598 Binding of Wnt3a 1 0.33 0.15 0.46
28 INT201636 Protein_catabolism of Cdk5r1 3 0.18 2.79 0.44
29 INT269613 Negative_regulation of Binding of EPHA3 2 0.11 0.27 0.43
30 INT326821 Positive_regulation of Protein_catabolism of Cdk5r1 1 0.13 1.9 0.41
31 INT340606 Positive_regulation of Wnt3a 1 0.61 0.49 0.4
32 INT181179 Binding of CYLD 4 0.43 7.06 0.39
33 INT16932 Localization of EPHA3 3 0.73 0.15 0.38
34 INT185432 Negative_regulation of CYLD 4 0.52 3.19 0.35
35 INT247937 Localization of Cdk5r1 3 0.41 1.21 0.3
36 INT51514 Positive_regulation of Wnt3a 3 0.04 3.32 0.28
37 INT298974 Transcription of Cdk5r1 1 0.04 1.64 0.28
38 INT273216 Negative_regulation of Gene_expression of Cdk5r1 1 0.25 1.73 0.25
39 INT185452 Regulation of CYLD 6 0.40 6.09 0.21
40 INT326823 Positive_regulation of Localization of Cdk5r1 1 0.09 0.9 0.2
41 INT134469 Positive_regulation of Binding of Cdk5r1 1 0.35 0.4 0.18
42 INT23890 Binding of CDK5R1 2 0.36 0.23 0.16
43 INT307231 Positive_regulation of Gene_expression of CYLD 1 0.45 2.37 0.14
44 INT185449 Regulation of Regulation of CYLD 1 0.21 2.03 0.13
45 INT221969 Negative_regulation of CDK5R1 1 0.41 0.44 0.13
46 INT51512 Negative_regulation of Positive_regulation of Wnt3a 1 0.04 1.3 0.13
47 INT51513 Positive_regulation of Positive_regulation of Wnt3a 1 0.04 1.31 0.13
48 INT269628 Regulation of EPHA3 2 0.12 0.2 0.12
49 INT307240 Localization of CYLD 3 0.72 3.09 0.1
50 INT101600 Regulation of Gene_expression of Cdk5r1 1 0.50 0.16 0.1
51 INT221976 Phosphorylation of CDK5R1 1 0.61 0.4 0.09
52 INT214463 Binding of Wnt3a 2 0.26 0.23 0.08
53 INT185440 Negative_regulation of Negative_regulation of CYLD 1 0.20 1.02 0.08
54 INT221965 Positive_regulation of Gene_expression of CDK5R1 1 0.67 0.29 0.08
55 INT221977 Transcription of CDK5R1 1 0.51 0.59 0.08
56 INT185437 Negative_regulation of Gene_expression of CYLD 3 0.52 2.41 0.05
57 INT221975 Regulation of Transcription of CDK5R1 1 0.26 0.15 0.05
58 INT269400 Positive_regulation of Phosphorylation of EPHA3 1 0.11 0.05 0.05
59 INT307229 Phosphorylation of CYLD 1 0.73 1.02 0.05
60 INT269388 Phosphorylation of EPHA3 3 0.21 0.16 0.04
61 INT171650 Protein_catabolism of CDK5R1 2 0.63 0.47 0.04
62 INT269599 Negative_regulation of Positive_regulation of EPHA3 1 0.11 0.47 0.03
63 INT269649 Positive_regulation of Localization of EPHA3 1 0.13 0 0.03
64 INT269618 Negative_regulation of Localization of EPHA3 1 0.11 0 0.03
65 INT214465 Localization of Wnt3a 2 0.52 0.29 0
66 INT251053 Gene_expression of Wnt3a 2 0.47 0.5 0
67 INT326853 Positive_regulation of Gene_expression of Wnt3a 1 0.36 0.2 0
68 INT201634 Negative_regulation of Positive_regulation of Cdk5r1 1 0.02 0.31 0
69 INT307235 Positive_regulation of Binding of CYLD 1 0.45 1.1 0
70 INT269607 Regulation of Positive_regulation of EPHA3 1 0.12 0 0
71 INT251054 Regulation of Localization of Wnt3a 1 0.27 0.07 0
72 INT269634 Positive_regulation of Positive_regulation of EPHA3 1 0.18 0 0
73 INT269626 Negative_regulation of Phosphorylation of EPHA3 1 0.11 0.11 0
74 INT307244 Regulation of Gene_expression of CYLD 1 0.24 1.84 0
75 INT269667 Regulation of Phosphorylation of EPHA3 1 0.12 0.11 0
76 INT230271 Transcription of DIXDC1 1 0.20 1.24 0
77 INT327507 Negative_regulation of Localization of CYLD 1 0.05 0.58 0
78 INT274108 Phosphorylation of Cdk5r1 1 0.01 0.84 0
79 INT251066 Regulation of Gene_expression of Wnt3a 1 0.31 0.07 0
80 INT269633 Regulation of Localization of EPHA3 1 0.12 0 0
81 INT326843 Negative_regulation of Gene_expression of Wnt3a 1 0.22 0.29 0
82 INT269612 Negative_regulation of EPHA3 1 0.11 0.17 0
83 INT307230 Regulation of Localization of CYLD 1 0.40 0.11 0
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