GO:0070508

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Name cholesterol import
Categary Process
Go Slim No
Go Link GO:0070508
Unique Molecular Interactions 124
Total Molecular Interactions 184
Total Single Events 1301
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cholesterol import. They are ordered first by their pain relevance and then by number of times they were reported for cholesterol import. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT334901 LDLR Positive_regulation of Crp 1 0.00 1.48 0.51
2 INT136749 COX5A Positive_regulation of Gene_expression of SCARB1 1 0.52 0.36 0.45
3 INT307781 Apoa1 Positive_regulation of LCAT 1 0.76 1.19 0.45
4 INT213027 Binding of Apoa1 and Scarb1 6 0.09 7.52 0.43
5 INT270043 Binding of Ldlr and Hdl1 1 0.01 2.3 0.43
6 INT307780 Apoa1 Positive_regulation of Soat1 1 0.04 1.14 0.42
7 INT254769 Binding of LDLR and Apoe 1 0.03 0 0.28
8 INT213029 Positive_regulation of Binding of Apoa1 and Scarb1 1 0.09 3.38 0.27
9 INT78296 Negative_regulation of Binding of Ptpra and Ldlr 1 0.22 0.25 0.24
10 INT186191 Binding of SCARB1 and TBP 1 0.03 2.57 0.24
11 INT78293 Binding of Apoe and Ldlr 1 0.20 0.25 0.24
12 INT78292 Negative_regulation of Binding of Apoe and Ldlr 1 0.23 0.25 0.24
13 INT78291 Binding of Ptpra and Ldlr 1 0.20 0.25 0.24
14 INT305798 Binding of APOA1 and OxP-11D 1 0.02 0.45 0.23
15 INT189321 Binding of Apoa1 and Hdlcl1 1 0.00 0.68 0.2
16 INT300193 Binding of APOA1 and INSL4 1 0.01 2.17 0.18
17 INT344707 Scarb1 Positive_regulation of Positive_regulation of Hdl1 1 0.14 0.88 0.14
18 INT229290 BAS Negative_regulation of LDLR 1 0.03 0.83 0.13
19 INT344705 Nr1h2 Regulation of Scarb1 1 0.04 1.53 0.12
20 INT270723 Negative_regulation of HMGCR Positive_regulation of LDLR 1 0.02 0.52 0.12
21 INT213042 Apoa1 Positive_regulation of Nos3 1 0.10 2.17 0.11
22 INT328313 Binding of CD36 and LDLR 1 0.00 0.63 0.11
23 INT99140 LDLR Positive_regulation of Localization of VCAM1 1 0.05 0.44 0.11
24 INT305780 Binding of APOA1 and LRCH2 1 0.00 0.19 0.1
25 INT300192 Gene_expression of APOA1 Positive_regulation of HSD11B1 1 0.16 1.08 0.08
26 INT279652 PPARA Positive_regulation of Gene_expression of Apoa1 1 0.00 0.75 0.07
27 INT326067 APOA1 Positive_regulation of Localization of APOE 1 0.61 4.22 0.07
28 INT71344 Ldlr Positive_regulation of Hdlcl1 1 0.01 0.69 0.06
29 INT66590 Gnrhr Regulation of Ldlr 1 0.02 0.4 0.06
30 INT71343 Negative_regulation of Ldlr Positive_regulation of Hdlcl1 1 0.01 0.69 0.06
31 INT186188 Binding of SCARB1 and PDZK1 1 0.53 0.54 0.05
32 INT335047 PPARA Positive_regulation of Gene_expression of APOA1 1 0.20 0.42 0.05
33 INT239348 Binding of Apoa1 and Hdl1 1 0.03 3.34 0.05
34 INT296023 Positive_regulation of Apoa2 Negative_regulation of APOA1 1 0.50 0.35 0.05
35 INT186185 Binding of SCARB1 and SCARB2 1 0.22 0.58 0.05
36 INT296025 Apoa2 Negative_regulation of APOA1 1 0.47 0.35 0.05
37 INT323056 LDLR Regulation of HSD11B1 1 0.01 1.2 0.05
38 INT288853 Binding of HSD11B1 and LDLR 1 0.26 1.52 0.04
39 INT236722 Ppara Positive_regulation of Binding of Apoa1 1 0.10 0.18 0.04
40 INT206083 LDLR Positive_regulation of Binding of STAT3 1 0.02 0.53 0.04
41 INT186187 LDLR Regulation of Gene_expression of SCARB1 1 0.17 1.71 0.04
42 INT288908 Apoa1 Positive_regulation of Gene_expression of HSD11B1 1 0.03 0.53 0.04
43 INT294217 Binding of PLG and Ldlr 1 0.33 0.06 0.04
44 INT206066 LDLR Positive_regulation of Phosphorylation of STAT3 1 0.02 0.52 0.04
45 INT290375 Binding of Scarb1 and Gopc 1 0.15 0.29 0.04
46 INT294210 Binding of Ldlr and Plat 1 0.42 0.06 0.04
47 INT247439 Binding of APOA1 and HSD11B1 3 0.32 5.01 0.03
48 INT213002 Binding of Scarb1 and Trib3 1 0.00 1.02 0.03
49 INT294206 Ldlr Positive_regulation of Grin1 1 0.26 0 0.03
50 INT213011 Binding of Scarb1 and Hdl1 1 0.13 0.96 0.03
51 INT186186 LDLR Regulation of SCARB1 1 0.08 0.65 0.03
52 INT239345 Apoa1 Positive_regulation of RCT 1 0.02 1.15 0.03
53 INT239351 Binding of CETP and Ldlr 1 0.15 1.01 0.03
54 INT251961 Binding of LDLR and SNRNP70 2 0.04 0.55 0
55 INT209984 Binding of LDLR and LRP1 1 0.08 0 0
56 INT247155 Binding of Phb2 and Scarb1 1 0.01 0.33 0
57 INT198920 Binding of Ldlr and Lrpap1 1 0.05 0.06 0
58 INT186190 OLR1 Positive_regulation of SCARB1 1 0.01 0.67 0
59 INT239332 Hdl1 Positive_regulation of Gene_expression of Apoa1 1 0.04 0.84 0
60 INT209987 Binding of APOE and LDLR 1 0.24 0 0
61 INT247444 Binding of APOA1 and APOC3 1 0.28 0.39 0
62 INT260519 Binding of Prnp and Scarb1 1 0.41 0.21 0
63 INT213017 Apoa1 Negative_regulation of Positive_regulation of Gtf3a 1 0.00 1.16 0
64 INT290374 Binding of Scarb1 and Ncapg2 1 0.23 0.43 0
65 INT247436 Binding of APOA1 and SACM1L 1 0.27 0.39 0
66 INT290193 Binding of APOA1 and Hdl1 1 0.01 1 0
67 INT206086 LDLR Positive_regulation of Localization of IL6 1 0.03 0.42 0
68 INT260520 Binding of Myc and Scarb1 1 0.33 0.16 0
69 INT316414 Binding of LDLR and T2dm2 1 0.00 1.54 0
70 INT239353 CETP Regulation of Apoa1 1 0.16 0.65 0
71 INT186189 LDLR Positive_regulation of Gene_expression of SCARB1 1 0.14 1.27 0
72 INT239342 Lcat Regulation of Apoa1 1 0.16 0.65 0
73 INT317842 Hdlcl1 Positive_regulation of Ldlr 1 0.00 1.11 0
74 INT290373 Binding of Cd36 and Scarb1 1 0.11 0 0
75 INT302596 Eef1a2 Negative_regulation of LDLR 1 0.14 0.31 0
76 INT277047 Binding of APOB and LDLR 1 0.25 0.82 0
77 INT268459 Binding of LDLR and Olr1 1 0.00 0.78 0
78 INT326060 Binding of ABCA1 and APOA1 1 0.39 1.5 0
79 INT353796 Binding of Ldlr and Apob 1 0.06 0.82 0
80 INT326058 Negative_regulation of PRKCA Negative_regulation of APOA1 1 0.15 0.32 0
81 INT326059 APOA1 Positive_regulation of Gene_expression of APOE 1 0.61 0.38 0
82 INT326064 APOA1 Positive_regulation of HMGCR 1 0.16 0.19 0
83 INT300199 PCSK9 Regulation of Gene_expression of LDLR 1 0.13 0.88 0
84 INT339699 LDLR Positive_regulation of SREBF2 1 0.08 1.08 0
85 INT213043 Regulation of Binding of Apoa1 and Scarb1 1 0.05 1.12 0
86 INT198925 Binding of App and Ldlr 1 0.14 0.15 0
87 INT339694 LDLR Positive_regulation of Gene_expression of SREBF2 1 0.08 1.08 0
88 INT283061 Binding of ERCC8 and LDLR 1 0.00 0.44 0
89 INT239321 Binding of Abca1 and Apoa1 1 0.11 1.61 0
90 INT239319 Pltp Regulation of Apoa1 1 0.22 0.65 0
91 INT353804 Binding of APOE and Ldlr 1 0.16 0.84 0
92 INT326057 APOA1 Regulation of Localization of APOE 1 0.54 1.36 0
93 INT290372 Binding of Ngfr and Scarb1 1 0.01 0.48 0
94 INT251964 Binding of LDLR and RS1 1 0.00 0.31 0
95 INT300197 Binding of APOA1 and C1S 1 0.39 3.56 0
96 INT239350 Eef1a2 Positive_regulation of Apoa1 1 0.22 0.86 0
97 INT247440 Binding of APOA1 and APOB 1 0.28 1.02 0
98 INT304270 Binding of Apoa1 and Scarb1 1 0.00 0.39 0
99 INT353797 Binding of Ldlr and Trf 1 0.04 0.19 0
100 INT353800 Binding of Ldlr and Cd320 1 0.29 0.83 0
101 INT312630 Agrn Positive_regulation of Ldlr 1 0.14 0.66 0
102 INT326066 APOA1 Positive_regulation of Positive_regulation of HMGCR 1 0.17 0.19 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cholesterol import. They are ordered first by their pain relevance and then by number of times they were reported in cholesterol import. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5164 Negative_regulation of Ldlr 83 0.58 55.01 7.87
2 INT8579 Gene_expression of Apoa1 13 0.76 35.89 7.21
3 INT10863 Positive_regulation of Ldlr 45 0.68 31.06 7.05
4 INT11826 Positive_regulation of LDLR 62 0.62 45.09 6.21
5 INT74614 Positive_regulation of Apoa1 16 0.68 23.95 5.04
6 INT136754 Gene_expression of SCARB1 64 0.77 43.28 4.82
7 INT181886 Gene_expression of Apoa1 40 0.64 40.53 4.56
8 INT57728 Regulation of LDLR 25 0.41 13.18 3.46
9 INT87517 Gene_expression of LDLR 73 0.69 37.35 3.32
10 INT5166 Binding of Ldlr 14 0.48 11.95 3.32
11 INT10057 Gene_expression of Ldlr 35 0.67 23.99 3.05
12 INT550 Negative_regulation of LDLR 66 0.43 44.71 3.04
13 INT10830 Regulation of Apoa1 11 0.44 15.1 3.04
14 INT194465 Gene_expression of Ldlr 27 0.76 31.36 2.73
15 INT21712 Positive_regulation of APOA1 32 0.67 21.64 2.64
16 INT181880 Positive_regulation of Apoa1 19 0.66 21.19 2.43
17 INT49313 Positive_regulation of Gene_expression of Apoa1 3 0.68 9.55 2.01
18 INT22863 Negative_regulation of Apoa1 10 0.57 10.68 1.86
19 INT136752 Positive_regulation of Gene_expression of SCARB1 5 0.69 10.63 1.76
20 INT72676 Gene_expression of APOA1 34 0.75 34.15 1.67
21 INT156484 Binding of Apoa1 4 0.47 6.78 1.63
22 INT181881 Positive_regulation of Gene_expression of Apoa1 13 0.48 14.31 1.45
23 INT181882 Localization of Apoa1 8 0.71 7.94 1.37
24 INT10829 Regulation of Ldlr 12 0.34 8.12 1.35
25 INT23199 Binding of LDLR 22 0.47 17.08 1.16
26 INT82703 Transcription of LDLR 6 0.64 0.4 1.13
27 INT181879 Negative_regulation of Apoa1 8 0.55 8.18 1.11
28 INT82707 Positive_regulation of Transcription of LDLR 1 0.62 0.34 0.98
29 INT129425 Negative_regulation of Ldlr 22 0.42 17.15 0.97
30 INT82702 Positive_regulation of Positive_regulation of LDLR 4 0.45 1.08 0.95
31 INT211557 Gene_expression of Scarb1 30 0.75 5.03 0.94
32 INT294479 Gene_expression of Scarb1 1 0.02 3.08 0.9
33 INT72672 Positive_regulation of Gene_expression of APOA1 4 0.67 3.81 0.89
34 INT181885 Binding of Apoa1 7 0.35 5.66 0.84
35 INT136753 Regulation of Gene_expression of SCARB1 2 0.60 7.79 0.77
36 INT136751 Negative_regulation of SCARB1 6 0.43 2.65 0.7
37 INT142802 Binding of Ldlr 8 0.47 5.08 0.65
38 INT136755 Negative_regulation of Gene_expression of SCARB1 2 0.57 6.61 0.63
39 INT212959 Binding of Scarb1 12 0.35 7.7 0.61
40 INT142800 Positive_regulation of Ldlr 21 0.68 14.75 0.6
41 INT181888 Regulation of Apoa1 5 0.26 5.07 0.6
42 INT213118 Negative_regulation of Gene_expression of Apoa1 2 0.42 2.86 0.6
43 INT200090 Positive_regulation of Gene_expression of Ldlr 5 0.37 3.67 0.59
44 INT20239 Regulation of APOA1 10 0.60 10.98 0.51
45 INT136757 Regulation of SCARB1 4 0.27 1.96 0.48
46 INT190882 Regulation of Gene_expression of Apoa1 4 0.23 3.67 0.43
47 INT197012 Regulation of Gene_expression of LDLR 4 0.40 1.31 0.4
48 INT190691 Negative_regulation of APOA1 12 0.42 15.9 0.39
49 INT181883 Negative_regulation of Negative_regulation of Apoa1 1 0.40 1.24 0.39
50 INT138380 Regulation of Transcription of Ldlr 1 0.38 0.21 0.38
51 INT138379 Transcription of Ldlr 1 0.59 0.21 0.38
52 INT252223 Positive_regulation of Gene_expression of Ldlr 3 0.55 10.28 0.37
53 INT72673 Transcription of APOA1 2 0.52 1.2 0.36
54 INT5168 Regulation of Binding of Ldlr 1 0.45 0 0.36
55 INT232235 Negative_regulation of Gene_expression of Ldlr 3 0.42 3.13 0.34
56 INT261209 Localization of Apoa1 4 0.73 2.61 0.33
57 INT16855 Binding of Scarb1 1 0.21 0 0.33
58 INT16856 Positive_regulation of Binding of Scarb1 1 0.27 0 0.33
59 INT307779 Positive_regulation of Localization of Apoa1 1 0.49 0.88 0.31
60 INT189968 Binding of APOA1 12 0.47 10.1 0.3
61 INT344673 Positive_regulation of Binding of Scarb1 1 0.16 0.82 0.28
62 INT197016 Positive_regulation of Gene_expression of LDLR 13 0.50 5.82 0.24
63 INT37790 Localization of Ldlr 5 0.38 2.29 0.23
64 INT307183 Positive_regulation of Gene_expression of Scarb1 1 0.07 0.93 0.22
65 INT186199 Binding of SCARB1 3 0.37 5.25 0.21
66 INT190874 Negative_regulation of Gene_expression of Apoa1 1 0.15 0.9 0.2
67 INT252222 Regulation of Ldlr 5 0.34 4.3 0.19
68 INT5165 Positive_regulation of Binding of Ldlr 1 0.50 0 0.19
69 INT239275 Regulation of Localization of Apoa1 1 0.19 1.62 0.18
70 INT290336 Negative_regulation of Scarb1 4 0.31 1.77 0.17
71 INT211552 Localization of Scarb1 3 0.60 1.27 0.17
72 INT5167 Negative_regulation of Binding of Ldlr 1 0.43 0 0.17
73 INT17474 Negative_regulation of Positive_regulation of LDLR 4 0.37 2.93 0.16
74 INT209992 Negative_regulation of Transcription of LDLR 2 0.29 0 0.16
75 INT87515 Negative_regulation of Gene_expression of LDLR 2 0.09 1.96 0.16
76 INT297577 Localization of APOA1 12 0.65 4.58 0.15
77 INT252219 Negative_regulation of Binding of Apoa1 1 0.16 0.95 0.15
78 INT211532 Localization of Ldlr 4 0.56 3.52 0.13
79 INT59956 Positive_regulation of SCARB1 3 0.49 0.99 0.12
80 INT215136 Regulation of Gene_expression of Ldlr 2 0.12 0.76 0.12
81 INT116739 Protein_catabolism of Ldlr 1 0.87 1.18 0.12
82 INT190693 Negative_regulation of Regulation of APOA1 1 0.09 1.94 0.11
83 INT34582 Negative_regulation of Positive_regulation of Ldlr 2 0.03 1.33 0.1
84 INT167019 Negative_regulation of Gene_expression of Ldlr 3 0.42 0.76 0.08
85 INT293307 Regulation of Gene_expression of Ldlr 3 0.19 2.77 0.07
86 INT348079 Negative_regulation of Negative_regulation of Ldlr 1 0.12 1.03 0.05
87 INT290345 Negative_regulation of Gene_expression of Scarb1 1 0.42 0.5 0.04
88 INT335114 Negative_regulation of Transcription of APOA1 1 0.16 0.46 0.04
89 INT197014 Localization of LDLR 8 0.63 3.29 0.03
90 INT297432 Positive_regulation of Localization of Ldlr 2 0.14 0.35 0.03
91 INT290334 Negative_regulation of Binding of Scarb1 1 0.31 0.12 0.03
92 INT255452 Negative_regulation of Gene_expression of APOA1 1 0.41 2.46 0.03
93 INT176889 Negative_regulation of Binding of LDLR 2 0.41 1.2 0
94 INT276260 Negative_regulation of Localization of LDLR 2 0.40 1.34 0
95 INT267959 Negative_regulation of Positive_regulation of APOA1 2 0.41 1.4 0
96 INT326078 Positive_regulation of Negative_regulation of APOA1 1 0.40 0.32 0
97 INT326072 Negative_regulation of Localization of APOA1 1 0.34 0.38 0
98 INT39405 Regulation of Binding of LDLR 1 0.17 0 0
99 INT255448 Positive_regulation of Binding of APOA1 1 0.48 2.88 0
100 INT353784 Protein_catabolism of Ldlr 1 0.52 1.85 0
101 INT255449 Positive_regulation of Positive_regulation of APOA1 1 0.48 1.44 0
102 INT332947 Positive_regulation of Negative_regulation of Ldlr 1 0.37 1.54 0
103 INT326079 Regulation of Localization of APOA1 1 0.36 0.24 0
104 INT336099 Transcription of Ldlr 1 0.25 0.36 0
105 INT186198 Positive_regulation of Transcription of SCARB1 1 0.49 0.67 0
106 INT213117 Negative_regulation of Positive_regulation of Apoa1 1 0.07 0.54 0
107 INT290350 Transcription of Scarb1 1 0.50 0.24 0
108 INT336103 Positive_regulation of Transcription of Ldlr 1 0.22 0.47 0
109 INT326068 Positive_regulation of Localization of APOA1 1 0.40 1.76 0
110 INT288894 Regulation of Localization of Apoa1 1 0.14 0.42 0
111 INT290341 Positive_regulation of Negative_regulation of Scarb1 1 0.32 0.69 0
112 INT170750 Negative_regulation of Negative_regulation of LDLR 1 0.07 0.93 0
113 INT212958 Positive_regulation of Scarb1 1 0.20 1.29 0
114 INT213135 Negative_regulation of Scarb1 1 0.02 2.06 0
115 INT268450 Protein_catabolism of LDLR 1 0.07 0.14 0
116 INT186195 Transcription of SCARB1 1 0.70 1.42 0
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