GO:0070668

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Name positive regulation of mast cell proliferation
Categary Process
Go Slim No
Go Link GO:0070668
Unique Molecular Interactions 75
Total Molecular Interactions 96
Total Single Events 456
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of mast cell proliferation. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of mast cell proliferation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT107578 Kitl Negative_regulation of Grin2b 1 0.12 2.05 2.36
2 INT140019 Avp Positive_regulation of Localization of Kitl 1 0.00 1 2.13
3 INT140023 Avp Positive_regulation of Gene_expression of Kitl 1 0.00 0.76 1.62
4 INT107579 Kitl Negative_regulation of Grin2a 1 0.10 1.02 1.18
5 INT99577 Binding of KITLG and Kit 3 0.34 2.33 1.11
6 INT53844 Penk Regulation of Kitl 1 0.00 0.9 1
7 INT53845 Positive_regulation of Penk Regulation of Kitl 1 0.00 0.9 1
8 INT149386 Binding of Lyn and TRPV4 1 0.40 1.14 0.91
9 INT167944 Binding of Oprm1 and Stat5a 1 0.00 0 0.85
10 INT209040 Il3 Positive_regulation of Cxcl1 1 0.04 0.38 0.73
11 INT209061 Il3 Positive_regulation of Elf1 1 0.06 0.38 0.73
12 INT209048 Il3 Positive_regulation of Il17a 1 0.03 0.38 0.73
13 INT209065 Il3 Positive_regulation of Ccr1 1 0.00 0.38 0.73
14 INT209062 Il3 Positive_regulation of Csf2 1 0.02 0.38 0.73
15 INT126614 Ppyr1 Negative_regulation of Phosphorylation of Stat5a 1 0.27 0.1 0.64
16 INT126615 Binding of Oprd1 and Stat5a 1 0.28 0.07 0.61
17 INT1211 Binding of Kitl and Cpz 1 0.27 0 0.58
18 INT1210 Negative_regulation of Binding of Kitl and Cpz 1 0.33 0 0.58
19 INT194916 Kitl Positive_regulation of Gene_expression of Mmp1a 1 0.00 0.85 0.52
20 INT194919 Kitl Positive_regulation of Gene_expression of VEGFA 1 0.01 0.85 0.52
21 INT184130 Epo Positive_regulation of Stat5a 1 0.31 0.26 0.52
22 INT184096 Il7 Positive_regulation of Stat5a 1 0.07 0.26 0.51
23 INT184132 Il2 Positive_regulation of Stat5a 1 0.09 0.26 0.51
24 INT151456 Binding of KITLG and Insrr 1 0.00 0.21 0.46
25 INT142273 KITLG Positive_regulation of Gene_expression of Tnf 1 0.07 0.9 0.43
26 INT148246 Binding of KITLG and Positive_regulation of Kit 1 0.04 0.43 0.38
27 INT148247 KITLG Positive_regulation of Kit 1 0.03 0.43 0.38
28 INT2428 Pag1 Regulation of Kitl 1 0.00 0.41 0.38
29 INT97549 KITLG Negative_regulation of Mc1r 1 0.01 0.15 0.3
30 INT284433 Kdm5d Regulation of KITLG 1 0.00 0.57 0.23
31 INT284432 KITLG Regulation of Kdm5d 1 0.00 0.57 0.23
32 INT239328 Hdl1 Regulation of Gene_expression of Kitl 1 0.08 1.86 0.2
33 INT305533 Runx1 Positive_regulation of Il3 1 0.03 0.28 0.19
34 INT249962 Binding of KIT and KITLG 6 0.19 3.69 0.17
35 INT327327 Ttpa Negative_regulation of Il3 1 0.01 0.4 0.17
36 INT162273 KITLG Negative_regulation of Gene_expression of Tyr 1 0.13 0.3 0.17
37 INT97547 KITLG Negative_regulation of Msx1 1 0.00 0.08 0.15
38 INT97548 KITLG Negative_regulation of a 1 0.01 0.08 0.15
39 INT184129 Socs2 Negative_regulation of Stat5a 1 0.22 0.05 0.13
40 INT129091 Binding of PIK3CG and Lyn 1 0.00 0.47 0.12
41 INT129075 Binding of Pik3r1 and Lyn 1 0.00 0.47 0.12
42 INT129093 Binding of Lyn and TCHP 1 0.00 0.49 0.12
43 INT129092 Binding of GRP and Lyn 1 0.00 0.48 0.12
44 INT261762 Il3 Positive_regulation of Stat6 1 0.15 0 0.11
45 INT162270 Kitl Positive_regulation of Gene_expression of Tyr 1 0.34 0.18 0.08
46 INT327749 Binding of KITLG and Il6 1 0.00 0.05 0.08
47 INT132791 TNF Positive_regulation of KITLG 1 0.12 0.6 0.08
48 INT132803 IL13 Positive_regulation of KITLG 1 0.12 0.73 0.08
49 INT132795 IL4 Positive_regulation of KITLG 1 0.12 0.73 0.08
50 INT132800 IL1B Positive_regulation of KITLG 1 0.19 0.6 0.08
51 INT184097 Cish Negative_regulation of Il3 1 0.10 0.62 0.07
52 INT217278 Kitl Regulation of Gene_expression of Ptges 1 0.02 0.1 0.05
53 INT200814 Epo Positive_regulation of Lyn 1 0.36 1.42 0.03
54 INT353192 Stat5a Positive_regulation of Plxna3 1 0.01 0 0
55 INT188295 Binding of KITLG and Ghrl 1 0.02 0.09 0
56 INT241500 Binding of Kit and Kitl 1 0.08 0.92 0
57 INT132796 IL13 Positive_regulation of Localization of KITLG 1 0.27 0.13 0
58 INT278388 Msu Positive_regulation of Phosphorylation of Lyn 1 0.17 0.12 0
59 INT132813 TNF Positive_regulation of Localization of KITLG 1 0.27 0.12 0
60 INT261838 Lyn Regulation of Trpv4 1 0.03 0.19 0
61 INT130901 Jag2 Negative_regulation of Positive_regulation of Kitl 1 0.00 0.05 0
62 INT261843 Lyn Regulation of Regulation of Trpv4 1 0.03 0.19 0
63 INT188272 Binding of KITLG and PCNA 1 0.01 0.17 0
64 INT132817 IL1B Positive_regulation of Localization of KITLG 1 0.44 0.12 0
65 INT347226 Hck Regulation of Gene_expression of Lyn 1 0.10 0.08 0
66 INT353190 Stat5a Positive_regulation of Cyp2c11 1 0.31 0 0
67 INT314689 Binding of KITLG and UBR1 1 0.00 0.71 0
68 INT188290 Ghrl Regulation of Gene_expression of Kitlg 1 0.02 0.15 0
69 INT132807 IL4 Positive_regulation of Localization of KITLG 1 0.28 0.13 0
70 INT337732 KITLG Positive_regulation of KIT 1 0.03 0 0
71 INT241539 Binding of Abl1 and Lyn 1 0.09 0.14 0
72 INT200818 Akt1 Positive_regulation of Negative_regulation of Lyn 1 0.25 1.02 0
73 INT241538 Negative_regulation of Binding of Abl1 and Lyn 1 0.11 0.14 0
74 INT347224 Lyn Regulation of Positive_regulation of Bcr 1 0.14 0.07 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of mast cell proliferation. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of mast cell proliferation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT1726 Positive_regulation of Kitl 65 0.70 38.81 44.85
2 INT1664 Gene_expression of Kitl 30 0.65 13.63 7.47
3 INT83531 Gene_expression of KITLG 54 0.65 26 7.07
4 INT13352 Regulation of Kitl 11 0.45 3.91 6.07
5 INT7524 Localization of Kitl 9 0.74 3.45 5.49
6 INT25832 Negative_regulation of Kitl 9 0.43 3.59 5.07
7 INT126608 Binding of Stat5a 7 0.48 0.46 4.38
8 INT1209 Binding of Kitl 14 0.37 6.72 4.3
9 INT75688 Binding of KITLG 24 0.30 11.73 4.06
10 INT146946 Gene_expression of Lyn 16 0.76 8.9 3.75
11 INT88255 Regulation of Positive_regulation of Kitl 2 0.00 1.72 3.47
12 INT99574 Positive_regulation of KITLG 10 0.39 6.74 2.96
13 INT126610 Phosphorylation of Stat5a 5 0.82 0.8 2.52
14 INT126473 Regulation of KITLG 5 0.14 7.86 2.34
15 INT146945 Positive_regulation of Lyn 6 0.49 2.81 2.25
16 INT184077 Positive_regulation of Il3 7 0.06 3.69 2
17 INT126609 Positive_regulation of Phosphorylation of Stat5a 1 0.69 0.26 1.79
18 INT20377 Gene_expression of Il3 8 0.65 0.82 1.77
19 INT316075 Negative_regulation of Negative_regulation of Kitl 1 0.06 0.42 1.41
20 INT126605 Negative_regulation of Binding of Stat5a 1 0.58 0.15 1.27
21 INT274898 Positive_regulation of Positive_regulation of Lyn 1 0.35 1.51 1.05
22 INT86559 Negative_regulation of KITLG 8 0.41 3.54 0.99
23 INT146939 Negative_regulation of Lyn 3 0.53 2.97 0.95
24 INT149383 Binding of Lyn 1 0.36 1.14 0.91
25 INT184015 Positive_regulation of Stat5a 9 0.46 3.32 0.86
26 INT63912 Regulation of Negative_regulation of Kitl 1 0.00 0.59 0.77
27 INT20383 Localization of Il3 2 0.43 0.75 0.72
28 INT126606 Negative_regulation of Stat5a 1 0.43 0.08 0.64
29 INT159942 Positive_regulation of Stat5a 3 0.41 0.95 0.61
30 INT126612 Negative_regulation of Phosphorylation of Stat5a 1 0.42 0.1 0.61
31 INT139259 Gene_expression of Kitlg 4 0.62 1.32 0.6
32 INT65701 Localization of KITLG 13 0.65 2.46 0.58
33 INT1208 Negative_regulation of Binding of Kitl 1 0.34 0 0.58
34 INT117091 Positive_regulation of Lyn 1 0.49 0.41 0.56
35 INT162272 Regulation of Gene_expression of KITLG 3 0.14 0.34 0.43
36 INT108650 Positive_regulation of Gene_expression of KITLG 2 0.33 2.57 0.41
37 INT142271 Regulation of Gene_expression of Kitlg 1 0.16 1.08 0.4
38 INT209026 Transcription of Il3 1 0.17 0.53 0.31
39 INT261820 Phosphorylation of Lyn 5 0.30 1.41 0.2
40 INT304142 Negative_regulation of Phosphorylation of Lyn 1 0.12 1.11 0.2
41 INT45888 Regulation of Localization of Kitl 1 0.45 0 0.18
42 INT35403 Negative_regulation of Kitlg 1 0.33 0.87 0.18
43 INT184024 Binding of Stat5a 1 0.25 0.11 0.17
44 INT45889 Positive_regulation of Binding of Kitl 1 0.50 0 0.17
45 INT184055 Positive_regulation of Binding of Stat5a 1 0.33 0.12 0.17
46 INT350667 Positive_regulation of Transcription of Stat5a 1 0.29 0.47 0.16
47 INT350637 Transcription of Stat5a 1 0.40 0.46 0.16
48 INT278361 Positive_regulation of Gene_expression of Lyn 6 0.41 0.63 0.15
49 INT111549 Phosphorylation of KITLG 2 0.37 1.13 0.15
50 INT304452 Regulation of Lyn 1 0.17 0 0.15
51 INT111550 Negative_regulation of Phosphorylation of KITLG 1 0.02 0.75 0.15
52 INT51380 Transcription of KITLG 3 0.52 1.56 0.14
53 INT327256 Regulation of Il3 1 0.05 0.41 0.13
54 INT220368 Negative_regulation of Positive_regulation of Stat5a 1 0.34 0.46 0.11
55 INT336177 Positive_regulation of Positive_regulation of KITLG 1 0.01 0.38 0.11
56 INT302610 Positive_regulation of Gene_expression of Kitl 4 0.33 0.63 0.09
57 INT139260 Positive_regulation of Gene_expression of Kitlg 1 0.46 0.1 0.09
58 INT350646 Negative_regulation of Positive_regulation of Stat5a 1 0.25 0.23 0.08
59 INT313905 Localization of Stat5a 1 0.21 0.33 0.08
60 INT162271 Negative_regulation of Gene_expression of KITLG 4 0.28 2.31 0.07
61 INT162267 Negative_regulation of Gene_expression of Kitl 1 0.26 0.18 0.07
62 INT162268 Regulation of Gene_expression of Kitl 1 0.27 0.18 0.07
63 INT241509 Negative_regulation of Gene_expression of Lyn 2 0.20 1.02 0.05
64 INT315847 Positive_regulation of Negative_regulation of Lyn 1 0.18 0.61 0.05
65 INT184061 Negative_regulation of Stat5a 2 0.29 1.85 0.04
66 INT173796 Gene_expression of Stat5a 5 0.56 1.41 0
67 INT200803 Phosphorylation of Stat5a 2 0.59 1.23 0
68 INT132820 Positive_regulation of Localization of KITLG 2 0.39 0.11 0
69 INT200800 Positive_regulation of Phosphorylation of Stat5a 1 0.36 0.24 0
70 INT211541 Phosphorylation of Kitl 1 0.60 0.24 0
71 INT278323 Positive_regulation of Phosphorylation of Lyn 1 0.22 0 0
72 INT278322 Negative_regulation of Localization of Lyn 1 0.20 0.11 0
73 INT278356 Localization of Lyn 1 0.35 0.11 0
74 INT211535 Positive_regulation of Phosphorylation of Kitl 1 0.37 0.24 0
75 INT200799 Positive_regulation of Gene_expression of Stat5a 1 0.36 0.37 0
76 INT200790 Positive_regulation of Positive_regulation of Stat5a 1 0.36 0.24 0
77 INT188294 Negative_regulation of Transcription of KITLG 1 0.06 0.16 0
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