GO:0070669

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Name response to interleukin-2
Categary Process
Go Slim No
Go Link GO:0070669
Unique Molecular Interactions 9
Total Molecular Interactions 12
Total Single Events 73
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to interleukin-2. They are ordered first by their pain relevance and then by number of times they were reported for response to interleukin-2. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT231751 Binding of Il2rg and Jak3 1 0.03 1.56 0.67
2 INT231750 LOC690550 Negative_regulation of Jak3 1 0.02 1.3 0.52
3 INT167946 Binding of SRC and Stat5b 1 0.28 0 0.38
4 INT278957 JAK3 Positive_regulation of Gene_expression of IL8 1 0.28 0.67 0.38
5 INT278955 JAK3 Positive_regulation of Gene_expression of PRKCA 1 0.12 0.65 0.37
6 INT278949 JAK3 Positive_regulation of Gene_expression of LEP 1 0.42 0.63 0.36
7 INT226346 Binding of IL21 and Positive_regulation of Positive_regulation of JAK3 1 0.08 0.48 0.18
8 INT184089 Gh Positive_regulation of Stat5b 1 0.13 1.3 0.1

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to interleukin-2. They are ordered first by their pain relevance and then by number of times they were reported in response to interleukin-2. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT145299 Negative_regulation of Jak3 25 0.48 17.66 7.13
2 INT145298 Gene_expression of Jak3 5 0.78 7.69 3.07
3 INT145297 Positive_regulation of Jak3 3 0.50 5.52 2.14
4 INT278981 Negative_regulation of JAK3 5 0.46 2.12 1.69
5 INT278975 Gene_expression of JAK3 3 0.52 1.03 0.97
6 INT226480 Positive_regulation of JAK3 4 0.45 0.96 0.95
7 INT167938 Positive_regulation of Phosphorylation of Stat5b 1 0.33 0 0.85
8 INT167942 Binding of Stat5b 1 0.26 0 0.82
9 INT345936 Regulation of JAK3 1 0.02 0.41 0.46
10 INT231744 Negative_regulation of Gene_expression of Jak3 1 0.32 0.9 0.43
11 INT167941 Phosphorylation of Stat5b 1 0.58 0 0.42
12 INT278972 Regulation of Negative_regulation of JAK3 1 0.21 0.36 0.37
13 INT293346 Binding of JAK3 1 0.12 0.34 0.26
14 INT278139 Regulation of Jak3 1 0.06 0.97 0.22
15 INT278146 Localization of Jak3 1 0.35 0.97 0.22
16 INT278142 Binding of Jak3 1 0.17 0.67 0.19
17 INT167940 Regulation of Stat5b 1 0.43 0 0.19
18 INT278141 Negative_regulation of Negative_regulation of Jak3 1 0.20 0.66 0.15
19 INT278140 Regulation of Negative_regulation of Jak3 1 0.21 0.43 0.11
20 INT278144 Positive_regulation of Negative_regulation of Jak3 1 0.23 0.55 0.11
21 INT228800 Regulation of Gene_expression of Jak3 1 0.13 0.29 0.09
22 INT353174 Gene_expression of Stat5b 1 0.48 0 0
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