GO:0070742

From wiki-pain
Jump to: navigation, search
Name C2H2 zinc finger domain binding
Categary Function
Go Slim No
Go Link GO:0070742
Unique Molecular Interactions 64
Total Molecular Interactions 89
Total Single Events 565
Pain Genes Associated 15

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for C2H2 zinc finger domain binding. They are ordered first by their pain relevance and then by number of times they were reported for C2H2 zinc finger domain binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT278690 LEF1 Negative_regulation of Gene_expression of IK 1 0.00 0.66 0.83
2 INT278697 LEF1 Negative_regulation of STAT6 1 0.00 0.44 0.78
3 INT804 Aap Negative_regulation of MBD2 1 0.01 0 0.57
4 INT1066 Gm5720 Positive_regulation of MBD2 1 0.00 0.73 0.42
5 INT34411 Ebf1 Regulation of LH 1 0.06 0 0.4
6 INT262307 CAPNS1 Regulation of TAF9 1 0.04 1.23 0.33
7 INT309366 Pax2 Negative_regulation of Transcription of Slc6a5 1 0.03 0 0.31
8 INT309369 Ptf1a Positive_regulation of Pax2 1 0.10 0 0.3
9 INT118418 Gata1 Positive_regulation of Transcription of Tac2 1 0.61 0.77 0.25
10 INT118419 Binding of Gata1 and Tac2 1 0.31 0.7 0.24
11 INT47600 Ccno Regulation of MBD2 1 0.00 0.22 0.24
12 INT87092 Binding of PPP4C and MBD2 1 0.05 0 0.16
13 INT123194 Bmp6 Positive_regulation of TAF9 1 0.18 0.61 0.14
14 INT123193 Bmp6 Positive_regulation of Negative_regulation of TAF9 1 0.18 0.61 0.14
15 INT309371 Lhx1 Positive_regulation of Gene_expression of Pax2 1 0.08 0.07 0.11
16 INT309372 Lhx5 Positive_regulation of Gene_expression of Pax2 1 0.09 0.07 0.11
17 INT286683 Gopc Positive_regulation of MBD2 1 0.01 1.07 0.11
18 INT118416 Gata2 Positive_regulation of Transcription of Tac2 1 0.27 0.2 0.07
19 INT168976 Binding of Wt1 and Calb2 1 0.01 1.39 0.07
20 INT118417 Gata1 Regulation of Gene_expression of Serpinb9g 1 0.17 0.12 0.06
21 INT181601 Binding of TP53 and WT1 1 0.30 0.9 0.05
22 INT170328 Gene_expression of Ido1 Positive_regulation of Hmga2 1 0.01 0.13 0.04
23 INT276583 Binding of Wt1 and IgG 1 0.07 0 0.04
24 INT289101 Binding of KCNA1 and LEF1 1 0.00 2.58 0.03
25 INT347164 NOTCH1 Negative_regulation of Gene_expression of EBF1 1 0.03 0.85 0.03
26 INT196948 Hmga2 Positive_regulation of Hdac1 1 0.36 0.23 0
27 INT276586 Binding of Wt1 and Actn1 1 0.34 0.41 0
28 INT337402 LEF1 Positive_regulation of E2F1 1 0.11 0 0
29 INT244839 Lbx1 Positive_regulation of Pax2 1 0.39 0 0
30 INT183648 Binding of Lef1 and Ctnnd2 1 0.07 1.05 0
31 INT337415 Negative_regulation of MIR203 Positive_regulation of Positive_regulation of LEF1 1 0.03 0.25 0
32 INT337405 MIR203 Regulation of LEF1 1 0.02 0.31 0
33 INT196959 Hmga2 Positive_regulation of Localization of E2f1 1 0.54 0.24 0
34 INT337411 Negative_regulation of MIR203 Positive_regulation of Gene_expression of LEF1 1 0.04 0.25 0
35 INT196940 Positive_regulation of Hmga2 Positive_regulation of E2f1 1 0.50 0.47 0
36 INT255809 Binding of SF1 and U2AF2 1 0.21 0.3 0
37 INT289102 KCNA1 Negative_regulation of Gene_expression of LEF1 1 0.00 0.44 0
38 INT289098 KCNA1 Regulation of LEF1 1 0.00 0.67 0
39 INT254043 Binding of BGLAP and EBF1 1 0.07 0.11 0
40 INT252900 PTTG1 Regulation of Gene_expression of TAF9 1 0.20 0.84 0
41 INT196961 Binding of Hmga2 and Rb1 1 0.48 6.47 0
42 INT337417 MIR203 Negative_regulation of LEF1 1 0.04 0.57 0
43 INT220822 Binding of Myc and LEF1 1 0.26 0.08 0
44 INT217151 Gene_expression of MIR98 Negative_regulation of HMGA2 1 0.24 1.08 0
45 INT304168 Binding of Gata1 and Sfpi1 1 0.08 0.07 0
46 INT275703 Binding of TTR and Ebf1 1 0.37 0.08 0
47 INT220766 Binding of MAX and LEF1 1 0.40 0.08 0
48 INT268600 Mirlet7a-1 Regulation of HMGA2 1 0.01 0.72 0
49 INT297691 Binding of Fut1 and Pax2 1 0.03 0 0
50 INT196956 Binding of Hmga2 and Hdac1 1 0.25 0.23 0
51 INT196947 Binding of Rb1 and Positive_regulation of Hmga2 1 0.50 0.3 0
52 INT196951 Hmga2 Positive_regulation of E2f1 1 0.50 0.98 0
53 INT252893 PTTG1 Positive_regulation of Gene_expression of TAF9 1 0.21 0.9 0
54 INT181599 Binding of EWSR1 and WT1 1 0.40 0.29 0
55 INT295859 Srsf1 Positive_regulation of Binding of U2af2 1 0.01 0 0
56 INT196942 Binding of E2f1 and Hmga2 1 0.39 0.87 0
57 INT217142 MIR98 Regulation of Gene_expression of HMGA2 1 0.40 2.22 0
58 INT196953 Hmga2 Negative_regulation of Rb1 1 0.59 0.35 0
59 INT276590 Binding of Wt1 and KTWS 1 0.02 0.3 0
60 INT289100 KCNA1 Regulation of Gene_expression of LEF1 1 0.00 0.68 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for C2H2 zinc finger domain binding. They are ordered first by their pain relevance and then by number of times they were reported in C2H2 zinc finger domain binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT152 Negative_regulation of MBD2 31 0.38 3.95 11.31
2 INT113 Positive_regulation of MBD2 33 0.49 6.76 7.49
3 INT252968 Positive_regulation of TAF9 11 0.45 5.28 3.68
4 INT34977 Gene_expression of Hmga2 11 0.76 12.39 3.07
5 INT252999 Gene_expression of TAF9 12 0.75 12.65 2.92
6 INT9119 Negative_regulation of TAF9 4 0.42 5.21 2.16
7 INT262317 Binding of TAF9 7 0.31 9.67 2.15
8 INT38374 Regulation of MBD2 8 0.10 0.72 2.09
9 INT118412 Gene_expression of Gata1 5 0.62 0.83 1.6
10 INT118413 Positive_regulation of Gene_expression of Gata1 3 0.40 0.68 1.56
11 INT278715 Gene_expression of LEF1 10 0.33 5.43 1.54
12 INT278727 Negative_regulation of Gene_expression of LEF1 3 0.11 1.59 1.47
13 INT152951 Negative_regulation of LEF1 5 0.41 3.22 1.31
14 INT22946 Gene_expression of MBD2 4 0.25 0.26 0.98
15 INT34978 Negative_regulation of Gene_expression of Hmga2 2 0.42 1.53 0.95
16 INT278710 Phosphorylation of LEF1 1 0.05 0.76 0.82
17 INT144995 Positive_regulation of Gata1 1 0.37 0.14 0.71
18 INT101209 Gene_expression of Wt1 19 0.72 25.77 0.7
19 INT88987 Gene_expression of HMGA2 8 0.77 10.46 0.64
20 INT13724 Positive_regulation of WT1 5 0.69 4.99 0.59
21 INT88694 Gene_expression of WT1 17 0.75 21.88 0.56
22 INT34409 Positive_regulation of Ebf1 2 0.60 1.16 0.56
23 INT34408 Positive_regulation of Positive_regulation of Ebf1 1 0.10 0 0.56
24 INT323004 Transcription of TAF9 1 0.05 0.79 0.54
25 INT8053 Regulation of Negative_regulation of MBD2 1 0.16 0 0.5
26 INT88170 Positive_regulation of HMGA2 2 0.69 2 0.48
27 INT322997 Localization of TAF9 1 0.05 1.2 0.4
28 INT202616 Binding of U2af2 3 0.01 0.31 0.39
29 INT88167 Negative_regulation of Positive_regulation of HMGA2 1 0.41 0.16 0.35
30 INT213507 Gene_expression of Pax2 10 0.67 1.41 0.34
31 INT111230 Transcription of LEF1 3 0.30 1.72 0.33
32 INT252969 Positive_regulation of Gene_expression of TAF9 5 0.67 5.22 0.32
33 INT309354 Regulation of Pax2 1 0.10 0 0.29
34 INT88988 Positive_regulation of Gene_expression of HMGA2 1 0.69 4.05 0.29
35 INT196937 Positive_regulation of Hmga2 3 0.68 2.47 0.28
36 INT126059 Positive_regulation of Gata2 1 0.02 0.87 0.28
37 INT309339 Negative_regulation of Localization of Pax2 1 0.15 0 0.28
38 INT34410 Localization of Ebf1 1 0.18 0 0.27
39 INT114703 Positive_regulation of Wt1 5 0.46 4.25 0.24
40 INT244742 Gene_expression of Gata2 2 0.54 0.18 0.23
41 INT353967 Positive_regulation of Gene_expression of Gata2 1 0.42 0.18 0.23
42 INT191176 Negative_regulation of U2AF2 2 0.01 0.32 0.21
43 INT55804 Negative_regulation of EBF1 1 0.18 0.69 0.2
44 INT154282 Positive_regulation of Gene_expression of WT1 3 0.55 3.41 0.19
45 INT145217 Negative_regulation of Ebf1 2 0.50 0.62 0.17
46 INT145219 Gene_expression of Ebf1 2 0.67 0.87 0.17
47 INT13723 Negative_regulation of Positive_regulation of WT1 1 0.03 1.26 0.17
48 INT145218 Negative_regulation of Gene_expression of Ebf1 1 0.35 0.49 0.17
49 INT41148 Binding of MBD2 1 0.18 0 0.17
50 INT319048 Transcription of WT1 2 0.56 1.87 0.16
51 INT101208 Positive_regulation of Gene_expression of Wt1 3 0.47 3.08 0.15
52 INT220570 Transcription of Gata1 2 0.05 0.91 0.14
53 INT309352 Localization of Pax2 1 0.27 0 0.14
54 INT204514 Localization of EBF1 2 0.65 0.67 0.13
55 INT55803 Positive_regulation of EBF1 2 0.58 0.68 0.13
56 INT146533 Gene_expression of EBF1 3 0.60 2 0.11
57 INT178195 Localization of Wt1 4 0.69 2.64 0.1
58 INT46899 Negative_regulation of Positive_regulation of MBD2 1 0.00 0 0.1
59 INT27567 Positive_regulation of Gene_expression of MBD2 1 0.01 0 0.09
60 INT47659 Localization of MBD2 2 0.70 0.72 0.08
61 INT252991 Regulation of TAF9 2 0.44 3.54 0.08
62 INT170298 Regulation of Gene_expression of Hmga2 1 0.01 0.48 0.08
63 INT168975 Binding of Wt1 14 0.43 7.37 0.07
64 INT166389 Binding of WT1 7 0.36 8.25 0.07
65 INT88990 Binding of HMGA2 1 0.48 0.95 0.07
66 INT120535 Positive_regulation of Negative_regulation of MBD2 1 0.01 0.22 0.07
67 INT170300 Positive_regulation of Gene_expression of Hmga2 2 0.68 4.51 0.06
68 INT170302 Regulation of Hmga2 2 0.44 0.94 0.06
69 INT244741 Positive_regulation of Gene_expression of Pax2 1 0.38 0 0.06
70 INT307902 Negative_regulation of Localization of Wt1 1 0.34 0.21 0.05
71 INT220802 Binding of LEF1 7 0.36 3.86 0.04
72 INT289116 Positive_regulation of Localization of LEF1 2 0.22 1.19 0.04
73 INT289110 Localization of LEF1 2 0.32 1.19 0.04
74 INT181604 Localization of WT1 1 0.63 1.41 0.03
75 INT347179 Negative_regulation of Gene_expression of EBF1 1 0.16 0.77 0.03
76 INT76371 Protein_catabolism of Hmga2 1 0.02 0.06 0.03
77 INT285960 Negative_regulation of WT1 6 0.47 10.02 0
78 INT276530 Negative_regulation of Wt1 5 0.53 2.97 0
79 INT285959 Negative_regulation of Gene_expression of WT1 3 0.46 4.9 0
80 INT234467 Binding of U2AF2 2 0.34 0.82 0
81 INT289127 Positive_regulation of LEF1 2 0.22 0.76 0
82 INT276519 Regulation of Wt1 2 0.24 1.7 0
83 INT276550 Transcription of Wt1 2 0.66 1.35 0
84 INT197523 Binding of EBF1 2 0.47 0.43 0
85 INT257701 Positive_regulation of Gene_expression of Ebf1 1 0.43 0.12 0
86 INT196931 Phosphorylation of Hmga2 1 0.80 0.4 0
87 INT276547 Positive_regulation of Binding of Wt1 1 0.63 0.29 0
88 INT244782 Negative_regulation of Pax2 1 0.44 0 0
89 INT307906 Negative_regulation of Transcription of Wt1 1 0.54 1.3 0
90 INT196923 Binding of Hmga2 1 0.47 2.5 0
91 INT337456 Positive_regulation of Binding of LEF1 1 0.22 0 0
92 INT300344 Localization of HMGA2 1 0.42 1.75 0
93 INT217195 Negative_regulation of HMGA2 1 0.55 3.54 0
94 INT234916 Gene_expression of Lef1 1 0.04 0.25 0
95 INT276551 Positive_regulation of Localization of Wt1 1 0.45 0 0
96 INT289129 Positive_regulation of Gene_expression of LEF1 1 0.13 0.76 0
97 INT196932 Negative_regulation of Binding of Hmga2 1 0.42 0.24 0
98 INT196938 Negative_regulation of Hmga2 1 0.42 0.23 0
99 INT276534 Negative_regulation of Binding of Wt1 1 0.38 0 0
100 INT257702 Binding of Ebf1 1 0.31 0.89 0
101 INT268581 Regulation of HMGA2 1 0.18 0.72 0
102 INT337461 Positive_regulation of Transcription of LEF1 1 0.22 0.26 0
103 INT289108 Negative_regulation of Transcription of LEF1 1 0.11 0.32 0
104 INT319051 Regulation of Positive_regulation of WT1 1 0.36 1.11 0
105 INT217225 Negative_regulation of Negative_regulation of HMGA2 1 0.55 2.4 0
106 INT213529 Negative_regulation of Gene_expression of Pax2 1 0.37 0.23 0
107 INT252984 Regulation of Gene_expression of TAF9 1 0.26 0.99 0
108 INT262679 Phosphorylation of Gata1 1 0.18 0.55 0
109 INT262696 Binding of Gata1 1 0.08 0.56 0
110 INT254048 Positive_regulation of Gene_expression of EBF1 1 0.11 0.32 0
111 INT307903 Negative_regulation of Gene_expression of Wt1 1 0.39 1.31 0
112 INT220775 Binding of Lef1 1 0.20 0.06 0
113 INT196921 Localization of Hmga2 1 0.74 0.44 0
114 INT289124 Negative_regulation of Positive_regulation of LEF1 1 0.11 0.34 0
115 INT254046 Protein_catabolism of EBF1 1 0.19 0.1 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox