GO:0070914

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Name UV-damage excision repair
Categary Process
Go Slim No
Go Link GO:0070914
Unique Molecular Interactions 84
Total Molecular Interactions 216
Total Single Events 964
Pain Genes Associated 2

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for UV-damage excision repair. They are ordered first by their pain relevance and then by number of times they were reported for UV-damage excision repair. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69872 Binding of MC1R and POMC 52 0.54 8.87 18.3
2 INT338167 Binding of CDKN2A and MC1R 1 0.42 6.14 5.76
3 INT211710 Binding of Mc1r and a 7 0.44 0.37 4.78
4 INT113223 POMC Regulation of MC1R 6 0.68 0.39 4.24
5 INT104977 MITF Regulation of Gene_expression of MC1R 1 0.69 0.91 3.71
6 INT107723 POMC Positive_regulation of MC1R 7 0.68 0.71 2.82
7 INT49242 Binding of Mc1r and Pomc 10 0.38 3.79 2.15
8 INT331105 Vmn1r71 Negative_regulation of Mc1r 1 0.04 0.64 2.07
9 INT110525 Binding of MC1R and OCA2 1 0.41 1.08 1.97
10 INT145072 ASIP Negative_regulation of MC1R 1 0.29 0 1.52
11 INT276282 Binding of Atrn and Mc1r 1 0.32 0.41 1.29
12 INT71109 Binding of INSRR and MC1R 1 0.01 0 1.27
13 INT140238 HELQ Regulation of MC1R 1 0.01 0.5 1.2
14 INT331108 Mc1r Positive_regulation of Mc4r 1 0.44 1.05 1.06
15 INT331107 Vmn1r71 Positive_regulation of Mc1r 1 0.05 0.5 1.05
16 INT127997 Binding of MC1R and RHCE 2 0.28 0.41 1.02
17 INT201614 Mc1r Regulation of Uvbi1 1 0.04 1.42 0.98
18 INT77859 EDN1 Positive_regulation of MC1R 2 0.64 0.34 0.94
19 INT162071 Gene_expression of MC1R Negative_regulation of Gene_expression of TNF 1 0.41 0.34 0.82
20 INT106859 EDN1 Positive_regulation of Transcription of MC1R 1 0.22 0 0.82
21 INT130286 MC1R Positive_regulation of Localization of IL10 1 0.24 0.07 0.79
22 INT124385 GRK6 Negative_regulation of MC1R 1 0.42 0.42 0.77
23 INT124384 ADRBK1 Negative_regulation of MC1R 1 0.40 0.42 0.77
24 INT99335 Binding of Agrp and Mc1r 1 0.30 0 0.77
25 INT113222 POMC Regulation of Gene_expression of MC1R 1 0.06 0 0.76
26 INT113224 Binding of ASIP and MC1R 1 0.00 0 0.75
27 INT131468 Positive_regulation of POMC Positive_regulation of MC1R 1 0.00 0 0.74
28 INT113225 POMC Regulation of Transcription of MC1R 1 0.03 0 0.74
29 INT104974 MITF Positive_regulation of MC1R 1 0.52 0.16 0.74
30 INT155139 Binding of MC1R and PTGES 3 0.09 0 0.7
31 INT81787 Binding of AGRP and MC1R 1 0.53 0 0.69
32 INT134652 Binding of MC1R and SUGT1 1 0.02 0.84 0.68
33 INT140235 ADRBK1 Positive_regulation of Binding of MC1R 1 0.46 0.31 0.68
34 INT140236 GRK6 Positive_regulation of Binding of MC1R 1 0.52 0.31 0.68
35 INT140234 Gene_expression of GRK6 Positive_regulation of Gene_expression of MC1R 1 0.52 0.31 0.68
36 INT140237 Gene_expression of ADRBK1 Positive_regulation of Gene_expression of MC1R 1 0.46 0.31 0.68
37 INT110526 OCA2 Regulation of MC1R 1 0.49 0.43 0.65
38 INT99170 Binding of Mc1r and Tyr 1 0.11 0.2 0.64
39 INT104973 SGCG Regulation of Gene_expression of MC1R 1 0.67 0.17 0.63
40 INT148352 Binding of MC1R and XRCC3 1 0.36 0.34 0.62
41 INT75040 Binding of GHSR and MC1R 1 0.02 0.34 0.6
42 INT136682 Binding of BRAF and MC1R 2 0.49 3.16 0.57
43 INT71110 Binding of MC1R and NDP 1 0.10 0 0.57
44 INT66020 Binding of Mc1r and RBM25 1 0.00 0.42 0.57
45 INT93508 Binding of ASIP and Mc1r 1 0.02 0 0.47
46 INT73831 Binding of Mc1r and Pld1 1 0.00 0.16 0.45
47 INT147404 NDP Positive_regulation of MC1R 1 0.22 0.25 0.45
48 INT288370 a Positive_regulation of Mc1r 1 0.39 0 0.44
49 INT201610 Binding of Mc1r and Braf 1 0.31 0.75 0.42
50 INT168202 Msx1 Negative_regulation of Gene_expression of Mc1r 1 0.21 0.49 0.35
51 INT130803 MC1R Regulation of Positive_regulation of Cdkn2a 1 0.17 0.82 0.34
52 INT108637 Binding of MC1R and NCOR2 1 0.00 0.1 0.32
53 INT112193 MC1R Regulation of Localization of Tnf 1 0.06 0.15 0.31
54 INT97543 Gtf3a Negative_regulation of Mc1r 1 0.05 0.15 0.3
55 INT97549 KITLG Negative_regulation of Mc1r 1 0.01 0.15 0.3
56 INT97546 Pomc Negative_regulation of Mc1r 1 0.40 0.15 0.3
57 INT75056 Binding of MC1R and Msx1 1 0.00 0.17 0.29
58 INT81791 AGRP Negative_regulation of MC1R 2 0.47 0 0.28
59 INT154674 Binding of MC1R and SNRPE 1 0.38 0.27 0.28
60 INT168203 Binding of Mc1r and Msx1 1 0.19 0.64 0.25
61 INT100280 TXN Positive_regulation of Gene_expression of MC1R 1 0.33 0.22 0.24
62 INT149973 MC1R Positive_regulation of Gene_expression of NR4A2 1 0.44 0.32 0.23
63 INT155702 MC1R Positive_regulation of CAMP 1 0.48 0 0.2
64 INT83585 Trh Positive_regulation of Mc1r 1 0.50 0.35 0.2
65 INT68852 MC1R Positive_regulation of Localization of POMC 1 0.31 0.47 0.19
66 INT68853 MC1R Regulation of Localization of POMC 1 0.30 0.47 0.19
67 INT201609 Uvbi1 Positive_regulation of Gene_expression of Mc1r 1 0.05 0.57 0.17
68 INT201608 Binding of Mc1r and Uvbi1 1 0.03 0.93 0.15
69 INT201622 Binding of Mark3 and Mc1r 1 0.33 0.74 0.15
70 INT201619 Binding of Cdk11b and Mc1r 1 0.28 0.74 0.15
71 INT161095 Agrp Regulation of MC1R 1 0.45 0 0.15
72 INT128499 KLK7 Regulation of Gene_expression of MC1R 1 0.01 0.09 0.15
73 INT81789 Binding of MC1R and GIPC1 1 0.01 0 0.13
74 INT103561 Binding of TP53 and Mc1r 1 0.03 1 0.13
75 INT77873 Uvbi1 Positive_regulation of MC1R 1 0.01 0.34 0.12
76 INT77857 TNF Negative_regulation of MC1R 1 0.35 0.34 0.12
77 INT77858 IL1B Positive_regulation of MC1R 1 0.55 0.34 0.12
78 INT81790 Regulation of Binding of AGRP and MC1R 1 0.26 0 0.12
79 INT77861 IL1B Regulation of Gene_expression of MC1R 1 0.49 0.31 0.12
80 INT83584 Binding of Mc1r and Trh 1 0.36 0.17 0.1
81 INT151136 MC1R Regulation of Mchr1 1 0.00 0.43 0.1
82 INT293973 Binding of POMC and Mc1r 1 0.37 1.8 0.07
83 INT293975 POMC Positive_regulation of Mc1r 1 0.50 0.34 0
84 INT201612 Binding of Kit and Mc1r 1 0.34 0.13 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for UV-damage excision repair. They are ordered first by their pain relevance and then by number of times they were reported in UV-damage excision repair. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT56130 Gene_expression of MC1R 259 0.78 62.7 97.55
2 INT21737 Binding of MC1R 129 0.48 45.45 56.54
3 INT62426 Gene_expression of Mc1r 127 0.78 42.99 48.01
4 INT62169 Positive_regulation of MC1R 72 0.69 14.56 27.52
5 INT84712 Regulation of MC1R 36 0.62 9.34 16.91
6 INT97448 Negative_regulation of Mc1r 20 0.58 7.37 12.91
7 INT65304 Positive_regulation of Gene_expression of MC1R 34 0.70 11.32 12.09
8 INT71030 Binding of Mc1r 39 0.48 10.27 12.02
9 INT64451 Negative_regulation of MC1R 21 0.59 4.94 9.22
10 INT84765 Positive_regulation of Mc1r 24 0.70 5.95 8.01
11 INT91609 Regulation of Gene_expression of MC1R 11 0.62 2.75 7.34
12 INT85632 Regulation of Mc1r 14 0.61 3.22 6.5
13 INT62422 Regulation of Gene_expression of Mc1r 12 0.62 2.28 5.93
14 INT69700 Transcription of MC1R 15 0.71 4.32 5.62
15 INT135727 Positive_regulation of Gene_expression of Mc1r 18 0.69 8.69 4.92
16 INT62424 Transcription of Mc1r 8 0.71 3.67 4.54
17 INT61136 Localization of MC1R 8 0.75 2.8 2.85
18 INT162074 Negative_regulation of Transcription of MC1R 1 0.42 1.05 2.65
19 INT155045 Negative_regulation of Gene_expression of Mc1r 7 0.43 1.04 2.33
20 INT117116 Positive_regulation of Positive_regulation of MC1R 7 0.49 1.57 1.91
21 INT69704 Positive_regulation of Binding of MC1R 2 0.50 1.44 1.85
22 INT162871 Localization of Mc1r 6 0.75 0.61 1.72
23 INT93505 Positive_regulation of Positive_regulation of Mc1r 2 0.70 0.33 1.45
24 INT128003 Negative_regulation of Gene_expression of MC1R 4 0.59 1.56 1.41
25 INT69875 Negative_regulation of Binding of MC1R 2 0.39 0.37 1.26
26 INT85626 Positive_regulation of Transcription of Mc1r 2 0.50 1.12 1.1
27 INT331103 Regulation of Transcription of Mc1r 1 0.61 1.1 1.09
28 INT106860 Regulation of Transcription of MC1R 1 0.45 0 1
29 INT107474 Positive_regulation of Negative_regulation of Mc1r 1 0.61 0.41 0.89
30 INT125413 Regulation of Regulation of MC1R 1 0.45 0.09 0.78
31 INT153419 Regulation of Binding of MC1R 1 0.40 1.38 0.7
32 INT69701 Positive_regulation of Transcription of MC1R 5 0.46 2 0.51
33 INT113978 Positive_regulation of Localization of MC1R 1 0.24 1.2 0.51
34 INT211706 Negative_regulation of Localization of Mc1r 1 0.42 0 0.37
35 INT117115 Regulation of Positive_regulation of MC1R 1 0.33 0.38 0.29
36 INT142717 Positive_regulation of Negative_regulation of MC1R 1 0.47 0.36 0.28
37 INT288358 Positive_regulation of Binding of Mc1r 1 0.41 0 0.19
38 INT85629 Regulation of Regulation of Mc1r 1 0.34 0.39 0.07
39 INT335614 Positive_regulation of Regulation of MC1R 1 0.23 0 0
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