GO:0070936

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Name protein K48-linked ubiquitination
Categary Process
Go Slim No
Go Link GO:0070936
Unique Molecular Interactions 37
Total Molecular Interactions 52
Total Single Events 111
Pain Genes Associated 11

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for protein K48-linked ubiquitination. They are ordered first by their pain relevance and then by number of times they were reported for protein K48-linked ubiquitination. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT59203 ecs Positive_regulation of Negative_regulation of Ube2d3 1 0.00 1.93 1.15
2 INT141911 Arih2 Regulation of Positive_regulation of Cpox 1 0.01 1.19 0.76
3 INT141910 Arih2 Regulation of Cpox 1 0.01 1.19 0.76
4 INT59202 ecs Positive_regulation of Ube2d3 1 0.00 0.98 0.59
5 INT263978 Binding of ADRB2 and TNFAIP3 1 0.01 0.5 0.32
6 INT334263 Rnf216 Positive_regulation of Protein_catabolism of Tlr4 1 0.00 0.18 0.18
7 INT328143 Gabrb3 Positive_regulation of Ube3a 1 0.56 0.99 0.11
8 INT328146 Gabrb3 Negative_regulation of Ube3a 1 0.48 0.99 0.11
9 INT224985 Binding of Ube3a and Snord116 1 0.34 0.45 0.08
10 INT328150 H2-Q13 Positive_regulation of Gene_expression of Ube3a 1 0.55 1.23 0.07
11 INT328148 H2-Q13 Positive_regulation of Ube3a 1 0.55 1.23 0.07
12 INT342726 Binding of Laptm5 and Park2 1 0.03 0.64 0.04
13 INT317301 Binding of Park2 and Park7 1 0.36 0.62 0
14 INT342725 Pink1 Positive_regulation of Phosphorylation of Park2 1 0.29 0.62 0
15 INT247574 Ube2e3 Positive_regulation of Hif1a 1 0.04 0.62 0
16 INT333030 Binding of Itch and Trpv4 1 0.14 0 0
17 INT317300 Binding of Park2 and Pink1 1 0.48 1.23 0
18 INT342727 Pink1 Positive_regulation of Park2 1 0.29 0.62 0
19 INT333046 Binding of Trpv4 and ITCH 1 0.39 0 0
20 INT317302 Binding of Park2 and Mul1 1 0.01 0.62 0
21 INT333033 Binding of Itch and Laptm5 1 0.01 0 0
22 INT259051 Binding of TP53 and UBE3A 1 0.01 3.48 0
23 INT232714 Binding of UBE2K and MMRN1 1 0.00 0.1 0
24 INT333031 Binding of Itch and Mul1 1 0.02 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for protein K48-linked ubiquitination. They are ordered first by their pain relevance and then by number of times they were reported in protein K48-linked ubiquitination. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT224975 Gene_expression of Ube3a 5 0.76 7.18 1.69
2 INT136574 Regulation of TNFAIP3 2 0.11 1.33 1.3
3 INT59200 Negative_regulation of Ube2d3 3 0.13 2.37 1.23
4 INT156976 Gene_expression of TNFAIP3 4 0.65 5.25 0.93
5 INT347182 Negative_regulation of TNFAIP3 3 0.23 5.6 0.84
6 INT264003 Positive_regulation of Transcription of TNFAIP3 1 0.38 1.01 0.65
7 INT263996 Transcription of TNFAIP3 1 0.39 0.99 0.64
8 INT224979 Negative_regulation of Ube3a 2 0.57 3.18 0.29
9 INT328135 Negative_regulation of Gene_expression of Ube3a 1 0.42 0.9 0.19
10 INT328136 Transcription of Ube3a 1 0.67 0 0.16
11 INT217993 Positive_regulation of Ube3a 1 0.41 0.62 0.16
12 INT334236 Positive_regulation of Rnf216 1 0.00 0.78 0.14
13 INT259063 Binding of UBE3A 2 0.36 1.15 0.09
14 INT114041 Regulation of Arih2 1 0.34 0.25 0.09
15 INT321381 Localization of Arih2 1 0.08 1.63 0.08
16 INT334248 Regulation of Rnf216 1 0.00 0.62 0.08
17 INT342696 Gene_expression of Park2 1 0.65 1.19 0.08
18 INT224950 Regulation of Gene_expression of Ube3a 1 0.25 0.68 0.07
19 INT247556 Binding of Ube2e3 2 0.07 1.24 0.04
20 INT319263 Localization of Ube3a 2 0.73 1.09 0.04
21 INT317299 Binding of Park2 1 0.36 0.61 0.04
22 INT244259 Gene_expression of UBE3A 4 0.78 1.91 0
23 INT217333 Positive_regulation of TNFAIP3 3 0.23 2.65 0
24 INT224970 Regulation of Ube3a 2 0.44 0.31 0
25 INT342695 Phosphorylation of Park2 1 0.79 0.62 0
26 INT232745 Binding of UBE2K 1 0.00 0.1 0
27 INT348456 Protein_catabolism of TNFAIP3 1 0.22 1.13 0
28 INT348453 Positive_regulation of Positive_regulation of TNFAIP3 1 0.17 1.06 0
29 INT244258 Negative_regulation of Gene_expression of UBE3A 1 0.59 0.82 0
30 INT217339 Protein_catabolism of UBE3A 1 0.14 1.79 0
31 INT328129 Binding of Ube3a 1 0.32 0.15 0
32 INT333019 Binding of Itch 1 0.13 0 0
33 INT333021 Negative_regulation of Positive_regulation of Itch 1 0.14 0 0
34 INT328131 Positive_regulation of Gene_expression of Ube3a 1 0.49 0.29 0
35 INT328134 Protein_catabolism of Ube3a 1 0.86 0 0
36 INT244260 Negative_regulation of UBE3A 1 0.59 0.86 0
37 INT333024 Positive_regulation of Itch 1 0.17 0 0
38 INT247561 Positive_regulation of Binding of Ube2e3 1 0.09 0.64 0
39 INT356161 Binding of Rnf216 1 0.02 0 0
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