GO:0070988

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Name demethylation
Categary Process
Go Slim No
Go Link GO:0070988
Unique Molecular Interactions 15
Total Molecular Interactions 16
Total Single Events 221
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for demethylation. They are ordered first by their pain relevance and then by number of times they were reported for demethylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT147575 Binding of Ahr and Cyp1a1 2 0.15 0.15 0.54
2 INT147579 Binding of ATF4 and Cyp1a1 1 0.01 0.15 0.54
3 INT335134 PPARA Negative_regulation of Cyp1a1 1 0.47 0 0.28
4 INT5935 Por Regulation of Oprm1 1 0.19 0.51 0.28
5 INT57171 Binding of RYBP and Cyp1a1 1 0.01 0 0.23
6 INT57964 Myo5a Regulation of Negative_regulation of Cyp1a1 1 0.00 0.1 0.2
7 INT134196 Ahr Regulation of Transcription of Cyp1a1 1 0.11 0.14 0.16
8 INT57170 Binding of Cyp1a1 and Cyp2b1 1 0.39 0 0.13
9 INT134201 Positive_regulation of Binding of AHR and Cyp1a1 1 0.21 0.07 0.1
10 INT134200 Binding of AHR and Cyp1a1 1 0.16 0.07 0.1
11 INT238472 Binding of AVP and POR 1 0.02 0.85 0.09
12 INT342232 Binding of POR and SEPP1 1 0.02 0.75 0.08
13 INT22568 Cyp1a1 Positive_regulation of Tcf21 1 0.04 0 0.06
14 INT264979 Binding of POR and BAG3 1 0.15 0.38 0
15 INT197295 Positive_regulation of Binding of Ahr and Cyp1a1 1 0.20 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for demethylation. They are ordered first by their pain relevance and then by number of times they were reported in demethylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT185 Regulation of Cyp1a1 18 0.54 2.71 5.56
2 INT2435 Negative_regulation of Cyp1a1 15 0.58 3.32 5.16
3 INT186 Positive_regulation of Cyp1a1 30 0.70 5 5.02
4 INT38384 Regulation of Por 5 0.47 0.58 2.4
5 INT12131 Gene_expression of POR 17 0.77 9.42 2.17
6 INT19409 Binding of Cyp1a1 12 0.48 2.58 1.97
7 INT59302 Positive_regulation of POR 19 0.49 15.18 1.95
8 INT17862 Localization of Cyp1a1 5 0.74 0.34 1.34
9 INT151 Positive_regulation of Por 5 0.62 0.42 1.31
10 INT13674 Gene_expression of Cyp1a1 13 0.65 2.22 1.25
11 INT49013 Gene_expression of Por 6 0.75 2.19 1.22
12 INT115821 Transcription of Por 1 0.33 0.51 1.02
13 INT49012 Regulation of Gene_expression of Por 1 0.44 0 1.02
14 INT58960 Regulation of POR 5 0.25 1.04 0.68
15 INT115826 Transcription of Cyp1a1 4 0.52 1.15 0.53
16 INT2438 Regulation of Regulation of Cyp1a1 1 0.27 0 0.52
17 INT40164 Binding of Por 2 0.37 0.5 0.51
18 INT265 Negative_regulation of Por 4 0.59 0.34 0.41
19 INT27414 Positive_regulation of Negative_regulation of Cyp1a1 1 0.49 0.44 0.41
20 INT115835 Negative_regulation of Positive_regulation of Cyp1a1 2 0.32 1.35 0.36
21 INT12249 Binding of POR 5 0.35 2.76 0.35
22 INT13676 Negative_regulation of Gene_expression of Cyp1a1 1 0.33 0.1 0.29
23 INT12132 Positive_regulation of Gene_expression of POR 5 0.31 1.96 0.27
24 INT99628 Positive_regulation of Gene_expression of Cyp1a1 4 0.25 1.3 0.27
25 INT52176 Positive_regulation of Binding of Cyp1a1 1 0.44 0 0.26
26 INT115834 Positive_regulation of Transcription of Cyp1a1 2 0.38 0.64 0.23
27 INT64189 Protein_catabolism of POR 1 0.37 0.16 0.18
28 INT134195 Regulation of Transcription of Cyp1a1 1 0.13 0.14 0.16
29 INT115825 Positive_regulation of Gene_expression of Por 2 0.22 0.47 0.12
30 INT17866 Positive_regulation of Localization of Cyp1a1 1 0.49 0 0.12
31 INT167018 Negative_regulation of POR 3 0.37 1.9 0.11
32 INT115833 Negative_regulation of Transcription of Por 1 0.20 0.52 0.09
33 INT17863 Regulation of Positive_regulation of Cyp1a1 1 0.27 0 0.09
34 INT115828 Negative_regulation of Gene_expression of Por 1 0.20 0.52 0.09
35 INT67606 Localization of POR 3 0.68 1.22 0.06
36 INT323616 Phosphorylation of POR 1 0.05 0.7 0
37 INT323617 Positive_regulation of Phosphorylation of POR 1 0.03 0.7 0
38 INT264980 Transcription of POR 1 0.38 0.73 0
39 INT85223 Regulation of Localization of Cyp1a1 1 0.03 0.1 0
40 INT191529 Negative_regulation of Positive_regulation of POR 1 0.02 1.5 0
41 INT197269 Regulation of Gene_expression of Cyp1a1 1 0.16 0 0
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