GO:0070989

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Name oxidative demethylation
Categary Process
Go Slim No
Go Link GO:0070989
Unique Molecular Interactions 179
Total Molecular Interactions 211
Total Single Events 2640
Pain Genes Associated 12

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for oxidative demethylation. They are ordered first by their pain relevance and then by number of times they were reported for oxidative demethylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT92369 Binding of CYP2D6 and RYBP 1 0.25 0.15 1.73
2 INT100784 RYBP Positive_regulation of CYP3A4 1 0.44 0 1.54
3 INT123899 Binding of CYP3A4 and UGT2B7 1 0.52 0 1.46
4 INT90221 Binding of CYP2D6 and Cyp1a2 1 0.03 0.09 1.31
5 INT264988 Binding of CYP2C19 and CYP3A4 1 0.18 0.72 1.09
6 INT264987 Binding of CYP2C9 and CYP3A4 1 0.19 0.71 1.08
7 INT81583 Cyp3a23/3a1 Positive_regulation of st 1 0.04 0 1.08
8 INT81580 Cyp3a23/3a1 Positive_regulation of Nudt14 1 0.01 0 1.08
9 INT154237 Binding of CYP2D6 and Ugt2b7 1 0.41 0.75 1
10 INT130282 Cyp3a23/3a1 Positive_regulation of Gene_expression of Npy 1 0.15 0 0.94
11 INT279166 Binding of Cyp3a23/3a1 and Nr3c2 1 0.00 0.61 0.9
12 INT56273 RYBP Negative_regulation of Cyp1a2 1 0.01 0.17 0.9
13 INT136540 Binding of CYP2C9 and Ugt1a6a 1 0.27 0.81 0.86
14 INT253995 Binding of Cxcl12 and Cyp3a23/3a1 1 0.06 1.28 0.85
15 INT65807 Nr3c1 Positive_regulation of Cyp3a23/3a1 1 0.14 0 0.82
16 INT56275 RYBP Positive_regulation of Negative_regulation of Cyp1a2 1 0.01 0.17 0.81
17 INT102630 Cyp3a62 Negative_regulation of Cyp1a2 1 0.40 0 0.81
18 INT135781 Cyp3a23/3a1 Positive_regulation of Positive_regulation of Col1a1 1 0.01 0.78 0.8
19 INT130283 Cyp3a23/3a1 Positive_regulation of Transcription of Npy 1 0.10 0 0.79
20 INT100783 Binding of CYP2B6 and CYP3A4 2 0.17 2 0.77
21 INT56272 Cyp2e1 Positive_regulation of Cyp1a2 1 0.52 0.17 0.77
22 INT90959 PPIG Regulation of CYP2C9 1 0.43 0 0.75
23 INT88921 Positive_regulation of CYP2D6 Negative_regulation of ANTXR1 1 0.00 0.8 0.75
24 INT88922 CYP2D6 Negative_regulation of ANTXR1 1 0.00 0.8 0.75
25 INT218935 Cyp3a23/3a1 Regulation of Bcl2 1 0.00 1.08 0.74
26 INT218933 Cyp3a23/3a1 Regulation of Alpi 1 0.00 1.07 0.73
27 INT92370 Binding of CYP2B6 and CYP2D6 1 0.21 0 0.73
28 INT28184 Binding of CYP1A2 and CYP2D6 1 0.00 0 0.7
29 INT253994 Cyp3a23/3a1 Positive_regulation of Localization of Mif 1 0.09 0.96 0.69
30 INT113685 Binding of Cyp3a23/3a1 and Cyp2c11 1 0.35 0 0.65
31 INT351276 CYP2D6 Regulation of CYP1A2 1 0.12 0 0.63
32 INT330984 Negative_regulation of CYP2D6 Positive_regulation of Localization of CYP1A2 1 0.46 0 0.62
33 INT52816 Cyp3a23/3a1 Regulation of Localization of LH 1 0.03 0.16 0.6
34 INT315334 Binding of CYP3A4 and CDIPT 3 0.04 0.85 0.59
35 INT43692 Cyp3a23/3a1 Negative_regulation of Gh1 1 0.04 0 0.59
36 INT102671 Cyp1a2 Regulation of RYBP 1 0.00 0 0.58
37 INT102666 Cyp2e1 Regulation of Cyp1a2 1 0.20 0 0.58
38 INT43693 Cyp3a23/3a1 Positive_regulation of Localization of Prl 1 0.10 0 0.57
39 INT253998 Cyp3a23/3a1 Positive_regulation of Binding of Cxcl12 1 0.10 0.65 0.55
40 INT253990 Cyp3a23/3a1 Positive_regulation of Cxcl12 1 0.09 0.65 0.55
41 INT162503 AHR Regulation of CYP1A2 3 0.61 0.18 0.5
42 INT92803 Binding of CYP1A2 and VKORC1 1 0.31 0.12 0.48
43 INT92804 Positive_regulation of Binding of CYP1A2 and VKORC1 1 0.41 0.12 0.48
44 INT281982 Cyp3a23/3a1 Negative_regulation of Gene_expression of MDK 1 0.00 0.67 0.47
45 INT149690 M1 Negative_regulation of CYP2C8 1 0.19 0.05 0.46
46 INT218932 Cyp3a23/3a1 Regulation of Gene_expression of Alpi 1 0.00 0.53 0.46
47 INT123897 Binding of CYP3A4 and SLC35A2 1 0.39 0 0.45
48 INT122749 Cyp3a23/3a1 Positive_regulation of Phosphorylation of Akt1 1 0.07 0.24 0.41
49 INT123898 CYP3A4 Regulation of UGT2B7 1 0.22 0 0.41
50 INT159903 Binding of CYP2C8 and CYP2C9 1 0.42 0.22 0.35
51 INT301665 CYP2C9 Regulation of Binding of Ppara 1 0.26 1.79 0.34
52 INT78064 Cyp3a23/3a1 Regulation of Localization of Il6 1 0.08 0.07 0.32
53 INT132984 CYP3A4 Positive_regulation of Gene_expression of PPP4C 1 0.44 0 0.3
54 INT281970 Cyp3a23/3a1 Negative_regulation of Gene_expression of Tie1 1 0.00 0.46 0.3
55 INT218934 Cyp3a23/3a1 Negative_regulation of Ephb1 1 0.01 0.95 0.28
56 INT218928 Cyp3a23/3a1 Regulation of Transcription of Bcl2 1 0.00 0.56 0.28
57 INT78065 Cyp3a23/3a1 Negative_regulation of Gene_expression of Il6 1 0.12 0.07 0.27
58 INT218931 Cyp3a23/3a1 Regulation of Gene_expression of Akp3 1 0.00 0.55 0.27
59 INT169146 CYP2D6 Regulation of CYP3A 1 0.22 0 0.27
60 INT78061 Cyp3a23/3a1 Negative_regulation of Localization of Il6 1 0.12 0.07 0.27
61 INT169145 Regulation of CYP2D6 Regulation of CYP3A 1 0.22 0 0.27
62 INT114230 NR1I2 Positive_regulation of Positive_regulation of CYP2C9 1 0.13 0.61 0.27
63 INT130678 CYP2C9 Regulation of Cyp1a2 1 0.06 0 0.26
64 INT262353 TRIP10 Negative_regulation of Cyp1a2 1 0.03 0.8 0.26
65 INT130677 CYP2C9 Regulation of Binding of Ugt2b7 1 0.18 0 0.26
66 INT262227 Nr1h4 Regulation of Transcription of CYP3A4 1 0.08 0.12 0.26
67 INT162501 NEUROD1 Regulation of CYP1A2 2 0.22 0.09 0.25
68 INT272997 Binding of CYP3A4 and IL33 1 0.03 0 0.25
69 INT272998 IL33 Negative_regulation of CYP2D6 1 0.04 0 0.25
70 INT130663 Cyp1a2 Regulation of Binding of Ugt2b7 1 0.12 0 0.25
71 INT262229 Binding of CYP3A4 and Casr 1 0.03 0.37 0.24
72 INT115729 Binding of CYP3A7 and CYP3A4 1 0.44 0.05 0.23
73 INT351318 Binding of CYP2C19 and Cyp1a2 1 0.01 0.28 0.22
74 INT318039 CDIPT Positive_regulation of CYP3A4 1 0.06 0.06 0.2
75 INT262224 Sfn Negative_regulation of Transcription of CYP3A4 1 0.06 0.58 0.2
76 INT330986 CYP2C9 Positive_regulation of Gene_expression of CYP3A4 1 0.39 0 0.18
77 INT330985 CYP2C9 Positive_regulation of Gene_expression of CYP2C19 1 0.34 0 0.18
78 INT151895 Binding of CYP3A4 and GBE1 1 0.01 0.24 0.18
79 INT264101 Binding of CYP2D6 and Bche 1 0.07 0.33 0.18
80 INT104379 Gh1 Regulation of CYP2D6 1 0.07 0 0.17
81 INT85828 CYP3A4 Negative_regulation of CYP2D6 1 0.47 0.06 0.16
82 INT151894 NR1I2 Positive_regulation of CYP3A4 1 0.19 0.23 0.16
83 INT273561 Binding of CYP1A1 and CYP3A4 1 0.02 0.12 0.15
84 INT262231 Sfn Negative_regulation of Gene_expression of CYP3A4 1 0.06 0.26 0.14
85 INT262232 Nr1i2 Positive_regulation of Gene_expression of CYP3A4 1 0.17 0.26 0.14
86 INT343027 Binding of CYP3A4 and Azi1 1 0.02 0.75 0.14
87 INT262228 Nr1i2 Positive_regulation of Transcription of CYP3A4 1 0.17 0.27 0.13
88 INT254002 Binding of Cyp3a23/3a1 and Positive_regulation of Gene_expression of Mif 1 0.08 0.56 0.13
89 INT262226 Positive_regulation of Nr1i2 Positive_regulation of CYP3A4 1 0.17 0.68 0.12
90 INT97082 CYP2D6 Regulation of HAGH 1 0.02 0 0.11
91 INT97081 CYP3A4 Regulation of HAGH 1 0.02 0 0.11
92 INT155221 Binding of CYP3A4 and PNPLA4 1 0.09 0 0.1
93 INT339533 VEGFA Positive_regulation of Gene_expression of CYP2C8 1 0.09 0.57 0.09
94 INT264085 CYP2C19 Regulation of CYP3A4 1 0.02 0 0.09
95 INT160159 Gene_expression of CYP2C9 Positive_regulation of HSP90B2P 1 0.13 0.53 0.09
96 INT264103 Cyp2e1 Regulation of CYP2C9 1 0.04 0 0.09
97 INT264106 Cyp1a2 Regulation of CYP2D6 1 0.06 0 0.09
98 INT162507 Gtf3a Regulation of CYP1A2 1 0.00 0.09 0.09
99 INT264104 Cyp1a2 Regulation of CYP2C9 1 0.04 0 0.09
100 INT264083 CYP2C19 Regulation of CYP2D6 1 0.05 0 0.09
101 INT177296 Binding of CXADR and CYP3A4 1 0.30 0 0.09
102 INT264084 CYP2C19 Regulation of CYP2C9 1 0.03 0 0.09
103 INT264102 Cyp1a2 Regulation of CYP3A4 1 0.03 0 0.09
104 INT264107 Cyp2e1 Regulation of CYP2D6 1 0.05 0 0.09
105 INT264105 Cyp2e1 Regulation of CYP3A4 1 0.02 0 0.09
106 INT99476 Binding of CYP3A4 and ABCB1 2 0.28 0 0.08
107 INT219661 Binding of CYP2D6 and CYP2E1 1 0.30 0.22 0.08
108 INT177265 Binding of CYP3A4 and NR1H4 1 0.03 0 0.08
109 INT272774 Binding of Mc4r and Fto 1 0.30 0.66 0.08
110 INT168368 Binding of Cyp1a2 and Cyp2e1 1 0.37 0.08 0.07
111 INT22567 Cyp1a2 Positive_regulation of Tcf21 1 0.04 0 0.06
112 INT345925 IL6 Negative_regulation of Gene_expression of CYP1A2 1 0.13 0.18 0.06
113 INT264568 Binding of STS and CYP1A2 1 0.20 0.18 0.06
114 INT339695 Binding of CYP3A4 and TRO 1 0.06 0.57 0.05
115 INT319578 CYP3A4 Regulation of ALPPL2 1 0.00 0.56 0.05
116 INT180373 CYP2A6 Regulation of Cyp2d4 1 0.05 2.01 0.05
117 INT180372 CYP2A6 Regulation of Cyp1a2 1 0.03 2.02 0.05
118 INT235313 Cyp3a23/3a1 Positive_regulation of Ins1 1 0.14 0.82 0.05
119 INT292816 Binding of KCNJ11 and FTO 1 0.46 0.49 0.05
120 INT292815 Binding of CDC123 and FTO 1 0.50 0.48 0.05
121 INT177274 Binding of CYP3A4 and TNFRSF25 1 0.19 0 0.04
122 INT177273 Binding of CYP3A4 and FAUP1 1 0.02 0 0.04
123 INT339707 TRO Positive_regulation of CYP3A4 1 0.12 0.97 0.04
124 INT199406 Binding of CYP3A4 and PPIB 1 0.40 0 0.04
125 INT285385 Ass1 Positive_regulation of Transcription of Cyp1a2 1 0.00 0.09 0.03
126 INT292968 Fto Regulation of Gene_expression of Th 1 0.30 1.11 0
127 INT294894 CYP3A4 Negative_regulation of CYP2C19 1 0.08 0.13 0
128 INT139719 Binding of CYP2C9 and UGT1A6 1 0.19 0.1 0
129 INT292970 Fto Regulation of Th 1 0.18 0.48 0
130 INT125648 Cyp2c11 Positive_regulation of Transcription of Cyp3a23/3a1 1 0.42 0 0
131 INT292969 Fto Regulation of Gene_expression of Arc 1 0.24 0.55 0
132 INT96893 Binding of CYP3A4 and Orm2 1 0.07 0 0
133 INT262225 Binding of CYP3A4 and Nr1i2 1 0.13 0 0
134 INT20322 Binding of CYP1A2 and CYP26A1 1 0.00 0 0
135 INT96894 Binding of CYP3A4 and Orm1 1 0.00 0 0
136 INT223283 Binding of CYP2C9 and VKORC1 1 0.31 0.16 0
137 INT135130 Binding of CYP3A4 and NR1I2 1 0.34 0.31 0
138 INT199717 2610029G23Rik Regulation of CYP2D6 1 0.02 0.44 0
139 INT210417 APOB Negative_regulation of CYP2D6 1 0.01 0 0
140 INT294895 CYP3A4 Negative_regulation of CYP2C9 1 0.09 0.13 0
141 INT177290 GOPC Positive_regulation of CYP3A4 1 0.15 0 0
142 INT20325 Binding of CYP2D6 and CYP21A2 1 0.00 0 0
143 INT125659 Cyp2b2 Positive_regulation of Transcription of Cyp3a23/3a1 1 0.06 0 0
144 INT20326 Binding of CYP1A2 and CYP21A2 1 0.01 0 0
145 INT339700 CYP2B6 Positive_regulation of CYP3A4 1 0.13 0.3 0
146 INT53286 Binding of CYP1A2 and OPN1LW 1 0.03 0 0
147 INT96892 Negative_regulation of Binding of CYP3A4 and Orm2 1 0.08 0 0
148 INT199719 2610029G23Rik Regulation of CYP3A4 1 0.01 0.45 0
149 INT157283 CYP1A2 Positive_regulation of Gm7100 1 0.00 0 0
150 INT20324 Binding of CYP2D6 and CYP26A1 1 0.00 0 0
151 INT262223 Negative_regulation of Nr1i2 Negative_regulation of Gene_expression of CYP3A4 1 0.21 0.48 0
152 INT96895 Negative_regulation of Binding of CYP3A4 and Orm1 1 0.00 0 0
153 INT316183 Binding of CYP2C8 and ENO2 1 0.02 2.15 0
154 INT292971 Arc Positive_regulation of Gene_expression of Fto 1 0.19 0.8 0
155 INT135129 NR1I2 Regulation of Transcription of CYP3A4 1 0.58 0.6 0
156 INT125654 Cyp2e1 Positive_regulation of Transcription of Cyp3a23/3a1 1 0.43 0 0
157 INT95055 Binding of CYP1A2 and TXNRD1 1 0.04 0 0
158 INT169147 Binding of CYP2D6 and CYP3A 1 0.17 0 0
159 INT125649 Cyp2c6 Positive_regulation of Transcription of Cyp3a23/3a1 1 0.40 0 0
160 INT199801 gr Regulation of CYP2C9 1 0.08 0.63 0
161 INT210416 ITGA4 Negative_regulation of CYP2D6 1 0.01 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for oxidative demethylation. They are ordered first by their pain relevance and then by number of times they were reported in oxidative demethylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT15913 Negative_regulation of CYP2D6 174 0.59 22.45 70.91
2 INT50405 Negative_regulation of CYP3A4 238 0.59 53.65 51.51
3 INT56870 Gene_expression of CYP2D6 87 0.78 8.83 37.53
4 INT10797 Binding of CYP2D6 86 0.48 15.09 31.16
5 INT22211 Positive_regulation of CYP3A4 110 0.70 22 28.27
6 INT12129 Gene_expression of CYP3A4 107 0.78 23.11 27.6
7 INT39914 Negative_regulation of Cyp1a2 44 0.58 10.04 22
8 INT8765 Positive_regulation of Cyp3a23/3a1 63 0.67 22.28 20.39
9 INT68347 Negative_regulation of Cyp2d4 34 0.58 7.62 18.35
10 INT50579 Binding of CYP3A4 84 0.48 17.52 17.45
11 INT50404 Negative_regulation of CYP1A2 49 0.59 8.61 17.35
12 INT59929 Negative_regulation of CYP2C9 60 0.59 16.33 15.39
13 INT32706 Gene_expression of Cyp3a23/3a1 51 0.65 19.48 15.06
14 INT18191 Negative_regulation of Cyp3a23/3a1 48 0.57 10.21 13.38
15 INT28014 Localization of Cyp3a23/3a1 34 0.77 9.8 12.96
16 INT10798 Positive_regulation of CYP2D6 24 0.56 5.82 11.31
17 INT71189 Gene_expression of Cyp1a2 24 0.78 11.39 11.12
18 INT22210 Gene_expression of CYP1A2 45 0.78 4.95 10.66
19 INT55418 Regulation of CYP2D6 29 0.61 1.83 10.21
20 INT47860 Negative_regulation of Cyp1a2 20 0.57 6.06 10
21 INT68372 Regulation of CYP2C9 28 0.62 5.64 9.53
22 INT66819 Binding of CYP2C9 41 0.48 8.23 8.76
23 INT61599 Positive_regulation of CYP2C9 43 0.69 11.1 8.33
24 INT17867 Positive_regulation of Cyp1a2 39 0.69 2.58 7.57
25 INT57922 Gene_expression of CYP2C9 65 0.78 22.24 7.53
26 INT63057 Regulation of CYP3A4 31 0.61 5.75 6.92
27 INT20331 Positive_regulation of CYP1A2 31 0.69 8.6 5.92
28 INT28015 Regulation of Cyp3a23/3a1 19 0.40 6.32 5.79
29 INT68899 Binding of CYP1A2 19 0.48 2.33 5.73
30 INT23952 Gene_expression of Cyp2d4 18 0.78 4.76 5.31
31 INT230829 Localization of Cyp2d4 3 0.63 0.61 5.18
32 INT49292 Positive_regulation of Cyp1a2 17 0.69 6.16 4.96
33 INT110549 Negative_regulation of CYP2C8 15 0.59 0.54 4.78
34 INT55419 Regulation of CYP1A2 19 0.62 5.3 4.75
35 INT95538 Localization of CYP2D6 21 0.81 5.69 4.73
36 INT114718 Positive_regulation of Gene_expression of CYP3A4 17 0.49 4.69 4.69
37 INT65514 Gene_expression of Cyp1a2 25 0.77 6.12 4.6
38 INT140199 Positive_regulation of Gene_expression of Cyp3a23/3a1 9 0.45 4.91 4.56
39 INT60188 Positive_regulation of Cyp2d4 10 0.70 1.04 4.35
40 INT180338 Binding of Cyp2d4 12 0.47 6.87 4.09
41 INT158593 Negative_regulation of Negative_regulation of CYP3A4 5 0.43 1.16 4.01
42 INT71199 Positive_regulation of Gene_expression of Cyp1a2 4 0.69 1.41 3.36
43 INT8764 Positive_regulation of Positive_regulation of Cyp3a23/3a1 5 0.45 1.62 3.33
44 INT71195 Transcription of Cyp1a2 6 0.53 2.41 3.24
45 INT69564 Binding of Cyp3a23/3a1 11 0.34 4.67 3.2
46 INT100785 Protein_catabolism of CYP3A4 7 1.00 0.76 3.01
47 INT145710 Localization of CYP2C9 9 0.75 1.66 2.89
48 INT90960 Positive_regulation of Gene_expression of CYP2D6 9 0.50 2.06 2.76
49 INT87822 Binding of Cyp1a2 8 0.47 0.84 2.72
50 INT155216 Negative_regulation of Gene_expression of CYP3A4 9 0.56 3.81 2.71
51 INT126498 Positive_regulation of Negative_regulation of Cyp1a2 2 0.41 1.21 2.64
52 INT113081 Negative_regulation of Gene_expression of Cyp1a2 6 0.58 1.68 2.39
53 INT122709 Localization of CYP3A4 16 0.75 5.41 2.38
54 INT180343 Negative_regulation of Negative_regulation of Cyp2d4 2 0.36 0.49 2.38
55 INT56337 Regulation of Cyp1a2 8 0.27 1.09 2.33
56 INT20332 Positive_regulation of Positive_regulation of CYP1A2 4 0.69 0.68 2.17
57 INT143686 Negative_regulation of Gene_expression of CYP2D6 4 0.58 0.83 2.16
58 INT117898 Positive_regulation of Protein_catabolism of CYP3A4 1 0.67 0 2.08
59 INT149263 Regulation of Negative_regulation of CYP3A4 4 0.44 1 2.03
60 INT53390 Negative_regulation of Positive_regulation of Cyp1a2 2 0.35 0 2.03
61 INT65424 Positive_regulation of Gene_expression of CYP1A2 6 0.70 2.01 2.01
62 INT101410 Negative_regulation of Positive_regulation of CYP2C9 5 0.42 0.23 1.96
63 INT95797 Positive_regulation of CYP2C8 8 0.50 0.55 1.94
64 INT113683 Positive_regulation of Negative_regulation of Cyp3a23/3a1 2 0.49 0.48 1.94
65 INT65880 Gene_expression of CYP2C8 25 0.77 9.49 1.92
66 INT113684 Negative_regulation of Gene_expression of Cyp3a23/3a1 5 0.36 2.04 1.71
67 INT303913 Regulation of Regulation of CYP2D6 2 0.37 1.09 1.48
68 INT144738 Regulation of Gene_expression of CYP2D6 3 0.60 0 1.44
69 INT110551 Negative_regulation of Negative_regulation of CYP2D6 3 0.40 0.25 1.38
70 INT110550 Regulation of CYP2C8 3 0.45 1.59 1.34
71 INT83822 Protein_catabolism of CYP2C9 3 0.46 1.16 1.31
72 INT71281 Positive_regulation of Gene_expression of CYP2C9 13 0.62 5.11 1.3
73 INT117897 Negative_regulation of Protein_catabolism of CYP3A4 1 0.55 0 1.28
74 INT145488 Regulation of Cyp2d4 5 0.45 1.1 1.19
75 INT331001 Positive_regulation of Localization of CYP2D6 1 0.48 0.23 1.18
76 INT331006 Positive_regulation of Localization of CYP2C9 1 0.34 0.13 1.17
77 INT94396 Regulation of Cyp1a2 4 0.60 0.37 1.15
78 INT134955 Positive_regulation of Transcription of Cyp1a2 2 0.38 0.52 1.14
79 INT125541 Transcription of CYP3A4 7 0.69 2.14 1.02
80 INT130996 Positive_regulation of Regulation of CYP2C9 1 0.34 0 1
81 INT207325 Positive_regulation of Localization of Cyp3a23/3a1 1 0.42 0.61 0.98
82 INT79635 Localization of Cyp1a2 2 0.74 0.26 0.97
83 INT130671 Regulation of Gene_expression of Cyp1a2 2 0.43 1.27 0.87
84 INT95537 Transcription of CYP2D6 4 0.68 0.2 0.85
85 INT77927 Negative_regulation of Gene_expression of Cyp1a2 3 0.42 1.23 0.78
86 INT157282 Localization of CYP1A2 5 0.75 0.54 0.76
87 INT17868 Localization of Cyp1a2 3 0.75 0.05 0.75
88 INT94193 Transcription of Cyp1a2 4 0.65 1.29 0.74
89 INT17865 Regulation of Positive_regulation of Cyp1a2 2 0.45 0 0.74
90 INT144390 Positive_regulation of Negative_regulation of CYP2C9 4 0.49 2.03 0.72
91 INT145711 Regulation of Positive_regulation of CYP2C9 1 0.45 0.64 0.71
92 INT331008 Positive_regulation of Localization of CYP1A2 1 0.42 0.06 0.7
93 INT351280 Negative_regulation of Negative_regulation of CYP1A2 1 0.27 0.53 0.69
94 INT71188 Binding of Cyp1a2 5 0.44 0.58 0.68
95 INT207326 Regulation of Localization of Cyp3a23/3a1 1 0.43 0.74 0.65
96 INT53396 Regulation of Gene_expression of Cyp3a23/3a1 7 0.38 3.04 0.63
97 INT115823 Transcription of Cyp3a23/3a1 3 0.54 0.82 0.61
98 INT331002 Negative_regulation of Localization of CYP2D6 1 0.40 0.17 0.6
99 INT272772 Gene_expression of Fto 2 0.76 3.76 0.52
100 INT139306 Positive_regulation of Transcription of Cyp3a23/3a1 1 0.45 0.31 0.52
101 INT142624 Regulation of Negative_regulation of CYP2D6 1 0.27 0 0.51
102 INT199410 Negative_regulation of Binding of CYP3A4 4 0.43 0.96 0.5
103 INT80929 Negative_regulation of Positive_regulation of Cyp3a23/3a1 3 0.43 0.83 0.48
104 INT331000 Regulation of Positive_regulation of CYP2D6 1 0.43 0.3 0.47
105 INT135306 Binding of CYP2C8 10 0.46 4.37 0.46
106 INT135131 Regulation of Gene_expression of CYP3A4 8 0.59 4.32 0.44
107 INT130669 Regulation of Gene_expression of CYP2C9 2 0.25 0.69 0.44
108 INT28016 Negative_regulation of Localization of Cyp3a23/3a1 2 0.04 0 0.43
109 INT199409 Positive_regulation of Negative_regulation of CYP3A4 7 0.50 2.54 0.41
110 INT144386 Positive_regulation of Negative_regulation of CYP2D6 3 0.49 1.01 0.4
111 INT84396 Positive_regulation of Positive_regulation of Cyp1a2 2 0.24 0.22 0.34
112 INT155222 Positive_regulation of Transcription of CYP3A4 2 0.50 0.13 0.34
113 INT273509 Positive_regulation of Gene_expression of Cyp1a2 2 0.14 1.2 0.33
114 INT120670 Negative_regulation of Negative_regulation of CYP2C8 1 0.43 0 0.31
115 INT120669 Negative_regulation of Positive_regulation of CYP2C8 1 0.43 0 0.31
116 INT158581 Negative_regulation of Positive_regulation of CYP3A4 7 0.43 1.83 0.29
117 INT144387 Positive_regulation of Negative_regulation of CYP1A2 2 0.39 0.64 0.28
118 INT160135 Negative_regulation of Binding of CYP2C9 2 0.43 0.05 0.27
119 INT347186 Regulation of Negative_regulation of Cyp2d4 1 0.45 0.21 0.25
120 INT248664 Phosphorylation of Cyp3a23/3a1 2 0.14 0.94 0.24
121 INT17861 Positive_regulation of Localization of Cyp1a2 2 0.50 0.05 0.21
122 INT137622 Protein_catabolism of CYP2D6 2 0.38 0 0.17
123 INT344065 Negative_regulation of Binding of CYP2D6 1 0.15 0.05 0.17
124 INT344068 Negative_regulation of Binding of CYP1A2 1 0.15 0.05 0.17
125 INT345946 Negative_regulation of Localization of CYP3A4 1 0.09 0.56 0.16
126 INT261231 Negative_regulation of Gene_expression of Cyp2d4 2 0.42 0.36 0.14
127 INT314338 Positive_regulation of Transcription of Cyp1a2 1 0.13 0.38 0.14
128 INT231567 Negative_regulation of Gene_expression of CYP1A2 2 0.36 0.06 0.13
129 INT70583 Negative_regulation of Binding of Cyp3a23/3a1 1 0.30 0.09 0.12
130 INT162937 Regulation of Regulation of CYP1A2 1 0.45 0 0.12
131 INT162936 Regulation of Gene_expression of CYP1A2 1 0.45 0 0.12
132 INT113802 Transcription of Cyp2d4 1 0.69 0 0.11
133 INT137621 Protein_catabolism of CYP2C8 1 0.18 0 0.11
134 INT137619 Protein_catabolism of Cyp1a2 1 0.33 0 0.11
135 INT236140 Negative_regulation of Fto 1 0.03 2.42 0.11
136 INT100094 Regulation of Positive_regulation of CYP3A4 3 0.45 0.31 0.1
137 INT160162 Negative_regulation of Gene_expression of CYP2C9 2 0.41 0.37 0.09
138 INT115832 Negative_regulation of Transcription of Cyp3a23/3a1 1 0.34 0.51 0.09
139 INT135458 Negative_regulation of Negative_regulation of Cyp1a2 1 0.35 0.36 0.09
140 INT115836 Regulation of Regulation of Cyp3a23/3a1 1 0.17 0.49 0.09
141 INT272773 Binding of Fto 1 0.41 0.66 0.08
142 INT300138 Positive_regulation of FTO 2 0.36 2.64 0.07
143 INT262138 Positive_regulation of Regulation of CYP3A4 1 0.15 0.06 0.07
144 INT274055 Protein_catabolism of CYP1A2 1 0.47 0 0.06
145 INT73220 Regulation of Gene_expression of Cyp1a2 1 0.62 1.01 0.06
146 INT292953 Gene_expression of Fto 1 0.78 30.08 0.05
147 INT180329 Positive_regulation of Binding of Cyp2d4 1 0.33 1.97 0.05
148 INT306772 Positive_regulation of Negative_regulation of Cyp1a2 1 0.08 0.06 0.04
149 INT349930 Transcription of CYP2C8 1 0.57 0.27 0.03
150 INT264053 Positive_regulation of Negative_regulation of Cyp2d4 1 0.25 0.18 0.03
151 INT313942 Gene_expression of FTO 3 0.62 4.73 0
152 INT277114 Binding of FTO 3 0.34 3.93 0
153 INT135158 Transcription of CYP2C9 2 0.62 0.38 0
154 INT123100 Positive_regulation of Positive_regulation of CYP3A4 2 0.54 0 0
155 INT149251 Localization of CYP2C8 2 0.75 0.46 0
156 INT303488 Negative_regulation of Positive_regulation of Cyp1a2 1 0.18 0.96 0
157 INT277007 Negative_regulation of Transcription of CYP3A4 1 0.39 0.34 0
158 INT292960 Positive_regulation of Transcription of Fto 1 0.50 0.91 0
159 INT292954 Regulation of Fto 1 0.27 1.74 0
160 INT83244 Regulation of Positive_regulation of CYP1A2 1 0.43 1.18 0
161 INT158582 Negative_regulation of Positive_regulation of CYP1A2 1 0.41 0 0
162 INT292963 Regulation of Gene_expression of Fto 1 0.62 5.12 0
163 INT288288 Positive_regulation of Gene_expression of CYP2C8 1 0.50 0 0
164 INT292965 Negative_regulation of Gene_expression of Fto 1 0.59 5.69 0
165 INT330999 Negative_regulation of Positive_regulation of CYP2D6 1 0.40 0 0
166 INT292962 Positive_regulation of Gene_expression of Fto 1 0.70 9.41 0
167 INT292952 Transcription of Fto 1 0.72 2.21 0
168 INT213256 Regulation of Negative_regulation of CYP2C9 1 0.05 0.59 0
169 INT292966 Negative_regulation of Fto 1 0.59 3.83 0
170 INT253980 Positive_regulation of Binding of Cyp3a23/3a1 1 0.08 0 0
171 INT292955 Negative_regulation of Transcription of Fto 1 0.59 1.35 0
172 INT292956 Localization of Fto 1 0.65 0.45 0
173 INT313941 Positive_regulation of Gene_expression of FTO 1 0.36 1.4 0
174 INT169150 Regulation of Binding of CYP2D6 1 0.41 0 0
175 INT292964 Regulation of Negative_regulation of Fto 1 0.45 0.49 0
176 INT277008 Regulation of Transcription of CYP3A4 1 0.41 0.67 0
177 INT180326 Regulation of Gene_expression of Cyp2d4 1 0.18 0.77 0
178 INT292958 Positive_regulation of Fto 1 0.50 1.52 0
179 INT167110 Regulation of Binding of CYP1A2 1 0.45 0 0
180 INT292959 Regulation of Localization of Fto 1 0.39 0.45 0
181 INT248670 Negative_regulation of Regulation of Cyp3a23/3a1 1 0.08 0.16 0
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