GO:0071062

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Name alphav-beta3 integrin-vitronectin complex
Categary Component
Go Slim No
Go Link GO:0071062
Unique Molecular Interactions 14
Total Molecular Interactions 29
Total Single Events 95
Pain Genes Associated 2

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for alphav-beta3 integrin-vitronectin complex. They are ordered first by their pain relevance and then by number of times they were reported for alphav-beta3 integrin-vitronectin complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT113550 Binding of FN1 and VTN 6 0.30 5.24 1.91
2 INT24817 Binding of POMC and VTN 8 0.42 0.39 1.71
3 INT113549 Binding of VTN and alphavbeta3 integrin receptor 1 0.09 2.05 0.76
4 INT227911 Binding of VTN and MMRN1 1 0.01 1.16 0.56
5 INT106001 Binding of PLAUR and VTN 2 0.23 1.5 0.45
6 INT346148 Binding of ADM and VTN 1 0.15 0.93 0.39
7 INT346142 Positive_regulation of Binding of ADM and VTN 1 0.20 0.93 0.39
8 INT113551 Binding of ITGA3 and VTN 1 0.02 1.03 0.38
9 INT113555 Negative_regulation of Binding of FN1 and VTN 1 0.23 0.87 0.37
10 INT113559 Binding of PLAU and VTN 1 0.28 0.82 0.37
11 INT113554 Negative_regulation of Binding of PLAU and VTN 1 0.32 0.87 0.37
12 INT113547 Negative_regulation of Binding of PLAUR and VTN 1 0.26 0.87 0.37
13 INT106009 Binding of VTN and Plaur 1 0.05 1.37 0.15
14 INT231676 Binding of CD47 and ITGA5 1 0.02 0.08 0.07

Single Events

The table below shows the top 100 pain related interactions that have been reported for alphav-beta3 integrin-vitronectin complex. They are ordered first by their pain relevance and then by number of times they were reported in alphav-beta3 integrin-vitronectin complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT55733 Negative_regulation of VTN 47 0.58 47.22 5.68
2 INT24821 Binding of VTN 14 0.47 5.83 3
3 INT64709 Gene_expression of VTN 11 0.67 11.01 1.97
4 INT24819 Positive_regulation of VTN 8 0.49 3.52 1.23
5 INT78014 Negative_regulation of ITGA5 1 0.01 1.71 0.98
6 INT346193 Positive_regulation of Gene_expression of VTN 1 0.25 1.54 0.63
7 INT24818 Positive_regulation of Binding of VTN 1 0.49 0 0.18
8 INT64708 Negative_regulation of Gene_expression of VTN 1 0.37 0.44 0.09
9 INT72601 Gene_expression of ITGA5 3 0.32 0.51 0.06
10 INT201215 Negative_regulation of Binding of VTN 1 0.19 0.69 0
11 INT175261 Positive_regulation of Negative_regulation of VTN 1 0.02 0.77 0
12 INT279581 Regulation of VTN 1 0.01 0.18 0
13 INT72602 Positive_regulation of Gene_expression of ITGA5 1 0.03 0.16 0
14 INT72600 Positive_regulation of ITGA5 1 0.03 0.16 0
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