GO:0071156

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Name regulation of cell cycle arrest
Categary Process
Go Slim No
Go Link GO:0071156
Unique Molecular Interactions 91
Total Molecular Interactions 104
Total Single Events 720
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of cell cycle arrest. They are ordered first by their pain relevance and then by number of times they were reported for regulation of cell cycle arrest. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT192080 Foxm1 Positive_regulation of Cnr1 2 0.14 0.72 1.3
2 INT307047 Foxm1 Positive_regulation of Casp3 1 0.11 0.06 1.03
3 INT149390 Foxm1 Positive_regulation of Trpa1 1 0.28 0.31 0.94
4 INT56499 Neurod1 Positive_regulation of Maoa 1 0.47 0 0.8
5 INT111194 Binding of NEUROD1 and Pck1 1 0.39 0 0.75
6 INT81769 Binding of Chrna4 and Neurod1 1 0.35 0.07 0.69
7 INT154263 NEUROD1 Positive_regulation of Gene_expression of GAL 1 0.50 0.06 0.63
8 INT119745 NEUROD1 Regulation of Gene_expression of BHLHE22 1 0.11 0.26 0.53
9 INT95042 Binding of NEUROD1 and Olr1246 1 0.02 0.23 0.51
10 INT138353 Foxm1 Positive_regulation of Phosphorylation of Trpv1 1 0.10 0.31 0.51
11 INT138352 Foxm1 Positive_regulation of Trpa1 1 0.05 0.33 0.51
12 INT206010 Foxm1 Positive_regulation of Gene_expression of Il18 1 0.03 0.72 0.5
13 INT162499 Binding of AHR and NEUROD1 3 0.25 0.19 0.49
14 INT86088 Foxm1 Positive_regulation of Binding of Crygs 1 0.04 0 0.49
15 INT86089 Foxm1 Regulation of Binding of Crygs 1 0.02 0 0.49
16 INT171185 Binding of NEUROD1 and ACOT1 1 0.01 0.37 0.42
17 INT70010 Binding of Neurod1 and Insrr 1 0.01 0.11 0.37
18 INT97790 Foxm1 Negative_regulation of Gene_expression of Nos2 1 0.03 0.16 0.36
19 INT225119 Foxm1 Regulation of Localization of TGFB1 1 0.01 0.63 0.34
20 INT337412 AKT3 Negative_regulation of Localization of AKT2 1 0.09 0.5 0.32
21 INT337418 AKT2 Negative_regulation of Localization of AKT3 1 0.09 0.5 0.32
22 INT337414 AKT2 Negative_regulation of AKT1 1 0.10 0.5 0.32
23 INT298277 Pou4f1 Negative_regulation of Gene_expression of Neurod1 1 0.58 0.48 0.27
24 INT167488 Binding of NEUROD1 and GGNBP2 1 0.08 0 0.27
25 INT68298 Binding of Neurod1 and Abt1 1 0.24 0 0.26
26 INT162502 NEUROD1 Regulation of CYP1A1 2 0.07 0.09 0.25
27 INT162501 NEUROD1 Regulation of CYP1A2 2 0.22 0.09 0.25
28 INT225118 Foxm1 Positive_regulation of Gene_expression of MMP2 1 0.01 0.34 0.23
29 INT225117 Foxm1 Regulation of Gene_expression of FN1 1 0.01 0.4 0.22
30 INT203527 Pou4f1 Negative_regulation of Neurod1 1 0.32 0.54 0.2
31 INT18966 TNF Positive_regulation of NEUROD1 1 0.53 0.83 0.2
32 INT244054 Prkaca Regulation of Neurod1 1 0.02 0.06 0.19
33 INT221956 CDK5R1 Regulation of Positive_regulation of CDK5 1 0.21 0.62 0.19
34 INT306261 AKT2 Negative_regulation of Phosphorylation of FOXO1 1 0.25 0.41 0.17
35 INT286769 Tusc2 Regulation of Foxm1 1 0.02 1.55 0.15
36 INT10731 NEUROD1 Regulation of CD4 1 0.42 1.3 0.12
37 INT10732 NEUROD1 Regulation of CD9 1 0.49 1.29 0.12
38 INT297543 Neurod1 Regulation of Psen1 1 0.00 0.2 0.12
39 INT221958 CDK5R1 Positive_regulation of Positive_regulation of CDK5 1 0.36 0.38 0.1
40 INT139558 Chrna4 Regulation of Neurod1 1 0.17 0 0.1
41 INT297546 Neurod1 Regulation of Notch1 1 0.05 0.2 0.1
42 INT297548 Neurod1 Regulation of Hes1 1 0.05 0.2 0.1
43 INT171188 Positive_regulation of Binding of NEUROD1 and TNIP1 1 0.08 0 0.1
44 INT139557 Chrna4 Regulation of Gene_expression of Neurod1 1 0.17 0 0.1
45 INT171184 Binding of NEUROD1 and TNIP1 1 0.06 0 0.1
46 INT221959 Binding of CDK5 and CDK5R1 1 0.28 0.53 0.1
47 INT221954 Binding of CDK5 and CDK5R2 1 0.02 0.36 0.09
48 INT244018 Binding of Neurod1 and Trak2 1 0.01 0 0.04
49 INT213803 Binding of Foxm1 and Tfe3 1 0.00 1.09 0.03
50 INT249898 Binding of Neurod1 and Olig2 1 0.09 0.14 0.03
51 INT213810 Binding of Foxm1 and Tfeb 1 0.00 1.09 0.03
52 INT219352 CDK5 Negative_regulation of PAK1 1 0.22 0.72 0.03
53 INT314863 Binding of Neurod1 and Atoh7 1 0.18 0.27 0
54 INT197309 Ascl1 Regulation of Neurod1 1 0.01 0.13 0
55 INT197313 Atoh1 Regulation of Neurod1 1 0.01 0.13 0
56 INT206178 Foxm1 Positive_regulation of Protein_catabolism of Olr1 1 0.00 0.47 0
57 INT232045 Binding of FOXM1 and RNPC3 1 0.00 0.31 0
58 INT232051 Binding of FOXM1 and KRAS 1 0.00 0.63 0
59 INT206180 Foxm1 Positive_regulation of Transcription of Olr1 1 0.00 0.48 0
60 INT314851 Positive_regulation of Binding of Neurod1 and Atoh7 1 0.23 0.27 0
61 INT200651 AKT2 Regulation of AKT1 1 0.31 0.21 0
62 INT232044 Binding of FOXM1 and LMBRD1 1 0.00 0.32 0
63 INT249828 Foxm1 Positive_regulation of Transcription of BIRC5 1 0.56 0.12 0
64 INT249822 Foxm1 Positive_regulation of Transcription of Plk1 1 0.50 0.12 0
65 INT249824 Ppp4c Positive_regulation of Foxm1 1 0.24 0 0
66 INT232046 Binding of DDR1 and FOXM1 1 0.00 0.63 0
67 INT314864 Binding of Neurod1 and Positive_regulation of Gene_expression of Atoh7 1 0.25 0.27 0
68 INT249827 Foxm1 Positive_regulation of Transcription of Cenpb 1 0.56 0.12 0
69 INT341632 Binding of EGFR and FOXM1 1 0.02 0.56 0
70 INT283716 Neurod1 Positive_regulation of Pax6 1 0.23 0.46 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of cell cycle arrest. They are ordered first by their pain relevance and then by number of times they were reported in regulation of cell cycle arrest. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT13409 Gene_expression of NEUROD1 52 0.75 14.17 12.23
2 INT6019 Positive_regulation of NEUROD1 37 0.67 17.3 8.89
3 INT64370 Gene_expression of Neurod1 22 0.75 5.19 7.1
4 INT50337 Negative_regulation of Foxm1 24 0.43 11.12 6.48
5 INT6097 Negative_regulation of NEUROD1 30 0.57 9.71 6.24
6 INT6098 Binding of NEUROD1 17 0.47 3.4 5.99
7 INT55513 Binding of Foxm1 19 0.37 2.37 5.54
8 INT83735 Gene_expression of Foxm1 41 0.77 22.9 5.07
9 INT20011 Regulation of NEUROD1 10 0.44 3.83 3.53
10 INT200670 Gene_expression of AKT2 25 0.75 16.25 3
11 INT39856 Binding of Neurod1 8 0.47 1.44 2.88
12 INT50335 Positive_regulation of Foxm1 20 0.69 5.11 2.81
13 INT113203 Regulation of Foxm1 8 0.34 7.5 2.36
14 INT82048 Positive_regulation of Neurod1 7 0.49 2.39 2.13
15 INT13999 Positive_regulation of Positive_regulation of NEUROD1 5 0.67 4.07 1.86
16 INT65602 Negative_regulation of Neurod1 7 0.42 2.52 1.55
17 INT64371 Positive_regulation of Gene_expression of Neurod1 4 0.64 1.56 1.45
18 INT27356 Localization of NEUROD1 8 0.78 3.44 1.39
19 INT18971 Positive_regulation of Gene_expression of NEUROD1 8 0.67 1.91 1.23
20 INT160054 Localization of AKT2 4 0.73 1.93 1.18
21 INT97369 Regulation of Gene_expression of NEUROD1 1 0.26 0.25 1.12
22 INT138349 Phosphorylation of Foxm1 1 0.10 0.9 1.05
23 INT94210 Regulation of Neurod1 2 0.33 0.07 1.04
24 INT51906 Negative_regulation of Gene_expression of NEUROD1 4 0.57 1.56 0.91
25 INT160056 Positive_regulation of AKT2 3 0.48 1.43 0.88
26 INT127452 Positive_regulation of CDK5 5 0.32 1.88 0.87
27 INT271605 Regulation of Gene_expression of AKT2 1 0.44 0.81 0.87
28 INT72710 Negative_regulation of Negative_regulation of Foxm1 3 0.10 0.55 0.84
29 INT219358 Gene_expression of CDK5 9 0.58 5.65 0.81
30 INT52187 Regulation of Binding of NEUROD1 1 0.44 0 0.77
31 INT200669 Negative_regulation of AKT2 2 0.42 0.94 0.72
32 INT203749 Binding of FOXM1 10 0.31 6.1 0.64
33 INT249764 Regulation of Binding of Foxm1 1 0.39 0.19 0.58
34 INT206006 Negative_regulation of Gene_expression of Foxm1 4 0.43 2.63 0.56
35 INT86087 Negative_regulation of Binding of Foxm1 1 0.28 0 0.52
36 INT206009 Transcription of Foxm1 2 0.68 1.49 0.51
37 INT271604 Positive_regulation of Gene_expression of AKT2 2 0.49 0.22 0.47
38 INT76845 Regulation of Gene_expression of Neurod1 2 0.44 0.28 0.44
39 INT154042 Localization of Neurod1 1 0.02 0.08 0.44
40 INT60952 Negative_regulation of Regulation of NEUROD1 1 0.42 0.3 0.41
41 INT60953 Negative_regulation of Negative_regulation of NEUROD1 1 0.41 0.3 0.41
42 INT50336 Negative_regulation of Positive_regulation of Foxm1 1 0.30 0 0.38
43 INT156490 Protein_catabolism of Neurod1 1 0.34 0.16 0.37
44 INT249785 Positive_regulation of Gene_expression of Foxm1 13 0.69 4.71 0.36
45 INT221973 Negative_regulation of CDK5 4 0.57 2.26 0.36
46 INT51266 Transcription of Neurod1 2 0.69 0.19 0.35
47 INT47995 Positive_regulation of Regulation of NEUROD1 1 0.45 0.68 0.34
48 INT24861 Regulation of Positive_regulation of NEUROD1 2 0.44 0.39 0.33
49 INT323118 Positive_regulation of Localization of AKT2 2 0.49 0.48 0.31
50 INT104311 Positive_regulation of Transcription of NEUROD1 1 0.49 0.28 0.29
51 INT104309 Transcription of NEUROD1 1 0.69 0.28 0.29
52 INT201239 Gene_expression of FOXM1 9 0.51 4.07 0.19
53 INT203750 Positive_regulation of FOXM1 8 0.39 2.72 0.19
54 INT219375 Localization of CDK5 4 0.52 2.8 0.19
55 INT221974 Phosphorylation of CDK5 1 0.56 0.99 0.19
56 INT200676 Phosphorylation of AKT2 1 0.53 1.01 0.19
57 INT82049 Negative_regulation of Positive_regulation of Neurod1 1 0.41 0.61 0.18
58 INT48771 Positive_regulation of Localization of NEUROD1 2 0.49 1.5 0.16
59 INT221972 Regulation of CDK5 1 0.42 1.87 0.16
60 INT179260 Binding of AKT2 2 0.27 1.8 0.15
61 INT203751 Negative_regulation of FOXM1 2 0.20 0.94 0.11
62 INT341559 Positive_regulation of Gene_expression of CDK5 1 0.23 0.25 0.11
63 INT36311 Protein_catabolism of NEUROD1 1 0.86 0.51 0.09
64 INT117620 Regulation of Localization of NEUROD1 1 0.60 0.24 0.07
65 INT341567 Negative_regulation of Gene_expression of CDK5 1 0.27 0.24 0.07
66 INT219355 Binding of CDK5 3 0.35 2.02 0.06
67 INT249792 Regulation of Gene_expression of Foxm1 1 0.45 0.45 0.04
68 INT200687 Positive_regulation of Phosphorylation of AKT2 1 0.33 0.43 0.04
69 INT248201 Phosphorylation of Neurod1 1 0.28 0.07 0.04
70 INT249769 Localization of Foxm1 6 0.74 1.13 0
71 INT200678 Transcription of AKT2 1 0.47 0.57 0
72 INT207724 Transcription of FOXM1 1 0.58 0.85 0
73 INT200685 Negative_regulation of Gene_expression of AKT2 1 0.38 6.09 0
74 INT249793 Regulation of Transcription of Foxm1 1 0.45 0 0
75 INT249780 Positive_regulation of Binding of Foxm1 1 0.50 0.5 0
76 INT249768 Regulation of Localization of Foxm1 1 0.39 0 0
77 INT200686 Negative_regulation of Transcription of AKT2 1 0.28 0.58 0
78 INT323119 Protein_catabolism of AKT2 1 0.96 0 0
79 INT249776 Negative_regulation of Localization of Foxm1 1 0.37 0.46 0
80 INT203752 Regulation of FOXM1 1 0.02 0 0
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