GO:0071158

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Name positive regulation of cell cycle arrest
Categary Process
Go Slim No
Go Link GO:0071158
Unique Molecular Interactions 515
Total Molecular Interactions 646
Total Single Events 4465
Pain Genes Associated 20

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of cell cycle arrest. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of cell cycle arrest. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21
2 INT338167 Binding of CDKN2A and MC1R 1 0.42 6.14 5.76
3 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
4 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
5 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71
6 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63
7 INT162163 CDKN2A Positive_regulation of PLD2 1 0.24 0 1.24
8 INT75483 Binding of SGCG and TGFB1 1 0.52 2.27 1.19
9 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19
10 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
11 INT73461 PTPLA Positive_regulation of Transcription of TP53 1 0.06 0.99 0.96
12 INT129206 RYBP Positive_regulation of Gene_expression of TGFB1 1 0.00 1.04 0.95
13 INT330629 TP53 Negative_regulation of Gene_expression of Fos 1 0.30 1.76 0.94
14 INT101259 Gata6 Negative_regulation of Gene_expression of ALOX15 1 0.42 0.67 0.89
15 INT149559 Tgfb1 Positive_regulation of Gene_expression of Ccr5 1 0.00 0 0.88
16 INT149562 Tgfb1 Positive_regulation of CXCL10 1 0.00 0 0.88
17 INT149564 Tgfb1 Positive_regulation of Gene_expression of CXCL10 1 0.00 0 0.88
18 INT149560 Tgfb1 Positive_regulation of Ccr5 1 0.00 0 0.88
19 INT101258 Gene_expression of Gata6 Negative_regulation of Positive_regulation of ALOX15 1 0.42 0.65 0.87
20 INT330630 Binding of TP53 and Car1 1 0.23 1.56 0.86
21 INT222985 CP Positive_regulation of Positive_regulation of TGFB1 1 0.00 1.57 0.85
22 INT97057 Bcl2l1 Regulation of Gene_expression of Trp53 1 0.36 0.51 0.83
23 INT149561 Tgfb1 Positive_regulation of Gene_expression of CCL2 1 0.00 0 0.83
24 INT97058 Cpz Regulation of Gene_expression of Trp53 1 0.27 0.57 0.83
25 INT149563 Tgfb1 Positive_regulation of CCL2 1 0.00 0 0.83
26 INT149558 Tgfb1 Positive_regulation of Gene_expression of Cxcr4 1 0.00 0 0.82
27 INT149557 Tgfb1 Positive_regulation of Gene_expression of Ccl5 1 0.00 0 0.82
28 INT161485 Il1b Regulation of Gene_expression of TGFB1 1 0.47 1.21 0.77
29 INT161483 Slc7a12 Regulation of Gene_expression of TGFB1 1 0.14 1.21 0.77
30 INT161482 Il1b Negative_regulation of TGFB1 1 0.45 1.17 0.76
31 INT161484 Binding of TGFB1 and Il1b 1 0.37 1.16 0.73
32 INT302642 Binding of ARSA and TGFB1 1 0.05 0.28 0.68
33 INT354913 VDR Positive_regulation of TGFB1 1 0.05 1.33 0.67
34 INT101986 TP53 Positive_regulation of Gene_expression of GDF15 1 0.52 2.45 0.67
35 INT137017 Tgfb1 Positive_regulation of Gene_expression of Acta2 1 0.00 0.84 0.61
36 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 0.27 0.83 0.61
37 INT335995 Il10 Negative_regulation of Tgfb1 1 0.06 0.83 0.57
38 INT56088 TGFB1 Positive_regulation of Transcription of SERPINE1 1 0.46 0.83 0.57
39 INT302645 ARSA Positive_regulation of Gene_expression of TGFB1 1 0.08 0.28 0.55
40 INT89144 TGFB1 Regulation of Gene_expression of Tcstv1 1 0.00 0.53 0.53
41 INT254200 Mif Regulation of Trp53 1 0.02 0.96 0.52
42 INT92918 Atp6v0a2 Negative_regulation of Gene_expression of Tgfb1 1 0.01 0.83 0.52
43 INT138151 Tgfb1 Regulation of IL1B 1 0.01 0.29 0.49
44 INT89145 TGFB1 Positive_regulation of Tcstv1 1 0.00 0.49 0.49
45 INT138153 Tgfb1 Regulation of IL6 1 0.01 0.29 0.49
46 INT302643 ARSA Positive_regulation of Localization of TGFB1 1 0.08 0.12 0.49
47 INT138146 Tgfb1 Regulation of Mmp3 1 0.00 0.23 0.46
48 INT138149 Tgfb1 Regulation of Mmp2 1 0.00 0.23 0.46
49 INT164415 Tgfb1 Regulation of Crlf1 1 0.01 0.78 0.45
50 INT302829 Mapkapk5 Positive_regulation of Trp53 1 0.07 0.81 0.43
51 INT283714 Positive_regulation of Binding of Id2 and Homer1 1 0.08 1.34 0.42
52 INT283713 Binding of Id2 and Homer1 1 0.06 1.34 0.42
53 INT75488 Binding of TGFB1 and Tgfbr1 1 0.23 0.78 0.41
54 INT75487 Binding of TGFB1 and Tgfbr2 1 0.31 0.83 0.41
55 INT158032 Binding of CDKN2A and KRT20 1 0.28 0.59 0.4
56 INT92690 Tgfb1 Positive_regulation of Transcription of Fgf2 1 0.32 1.8 0.4
57 INT165567 Tnf Regulation of Gene_expression of Tgfb1 1 0.41 1.15 0.39
58 INT336340 Glp2r Positive_regulation of Gene_expression of TGFB1 1 0.14 0.67 0.39
59 INT94853 TGFB1 Positive_regulation of Gene_expression of COL7A1 3 0.06 0.57 0.38
60 INT353454 Binding of BRCA1 and IL17A 1 0.00 2.55 0.36
61 INT204071 HP Positive_regulation of Gene_expression of CDKN2A 1 0.00 3.48 0.34
62 INT354886 Thbs1 Regulation of Positive_regulation of Tgfb1 1 0.17 2.18 0.34
63 INT137018 Tgfb1 Positive_regulation of Pscs 1 0.01 0.43 0.34
64 INT137013 Tgfb1 Positive_regulation of Gene_expression of Pscs 1 0.01 0.43 0.34
65 INT353452 Binding of AGRP and BRCA1 1 0.00 3.89 0.34
66 INT225119 Foxm1 Regulation of Localization of TGFB1 1 0.01 0.63 0.34
67 INT130803 MC1R Regulation of Positive_regulation of Cdkn2a 1 0.17 0.82 0.34
68 INT333457 Binding of PPARA and TGFB1 1 0.04 0 0.34
69 INT56089 TGFB1 Regulation of SERPINE1 1 0.41 0.41 0.33
70 INT91814 Binding of TNF and TP53 1 0.14 2.2 0.32
71 INT299549 Binding of TGFB1 and Egf 1 0.02 0.32 0.32
72 INT166394 CDKN1B Regulation of Gene_expression of TP53 1 0.28 0.41 0.31
73 INT166396 IFI27 Regulation of Gene_expression of TP53 1 0.19 0.41 0.31
74 INT102849 Tgfb1 Positive_regulation of Gene_expression of Col3a1 1 0.04 0.85 0.3
75 INT333917 MDM2 Positive_regulation of Protein_catabolism of Trp53 1 0.01 1.23 0.3
76 INT333918 HDAC1 Regulation of Trp53 1 0.03 1.24 0.3
77 INT163761 MDM2 Positive_regulation of Gene_expression of TP53 1 0.40 0.86 0.3
78 INT200640 Agtr2 Positive_regulation of Gene_expression of TGFB1 1 0.03 1.35 0.29
79 INT200639 Ace Positive_regulation of Gene_expression of TGFB1 1 0.06 1.36 0.29
80 INT200631 AGT Positive_regulation of Gene_expression of TGFB1 1 0.06 1.36 0.29
81 INT300552 Napa Positive_regulation of Gene_expression of TGFB1 1 0.01 0.88 0.29
82 INT166952 LYRM4 Positive_regulation of Gene_expression of TP53 1 0.05 0.75 0.28
83 INT137033 Tgfb1 Positive_regulation of Gene_expression of Col1a1 1 0.01 0.42 0.28
84 INT225101 TGFB1 Positive_regulation of Localization of COL1A1 1 0.03 0.59 0.28
85 INT225100 TGFB1 Positive_regulation of Gene_expression of COL1A1 1 0.04 0.59 0.28
86 INT286042 Binding of Tp53 and Wwox 1 0.04 2.05 0.28
87 INT216127 EGR1 Regulation of Transcription of TP53 1 0.06 0.21 0.28
88 INT126942 Binding of PKD2 and ZACN 1 0.00 1.38 0.28
89 INT302837 Binding of TNFRSF10D and Trp53 1 0.01 0.98 0.28
90 INT306267 Binding of INCENP and TP53 1 0.02 0.83 0.27
91 INT137032 Il6 Positive_regulation of Localization of Tgfb1 1 0.04 0.51 0.27
92 INT216128 EGR1 Regulation of TP53 1 0.11 0.21 0.27
93 INT352931 Prkaca Regulation of TP53 1 0.13 1.01 0.26
94 INT353448 BRCA1 Positive_regulation of CCL2 1 0.01 1.37 0.26
95 INT83395 Binding of IL1RN and Tgfb1 1 0.01 0.17 0.26
96 INT352930 Prkaca Regulation of Phosphorylation of TP53 1 0.13 1.02 0.26
97 INT353449 BRCA1 Positive_regulation of IL4 1 0.00 1.37 0.26
98 INT182325 TP53 Negative_regulation of Transcription of Birc5 1 0.01 1.34 0.26
99 INT353455 BRCA1 Positive_regulation of IL13 1 0.00 1.37 0.26
100 INT147593 Binding of CDK4 and CDKN2A 1 0.42 0.23 0.26
101 INT172975 Trp53 Positive_regulation of Cdkn1a 1 0.03 1.35 0.26
102 INT139094 Csf2 Regulation of Tgfb1 1 0.42 0.58 0.26
103 INT147592 Positive_regulation of Binding of CDK4 and CDKN2A 1 0.44 0.23 0.26
104 INT352893 PTGDS Regulation of TP53 1 0.16 1.02 0.26
105 INT125516 TP53 Regulation of GDF15 1 0.10 0.47 0.26
106 INT271450 Thy1 Regulation of TGFB1 1 0.00 0.62 0.25
107 INT337086 Mif Negative_regulation of Localization of Trp53 1 0.16 1.64 0.25
108 INT222981 TGFB1 Positive_regulation of Gene_expression of MMRN1 1 0.09 1.62 0.25
109 INT337091 Mif Negative_regulation of Positive_regulation of Trp53 1 0.16 1.64 0.25
110 INT156879 Gene_expression of TP53 Negative_regulation of Positive_regulation of PDF 1 0.45 0.9 0.24
111 INT181900 TP53 Negative_regulation of Gene_expression of NOS1 1 0.03 0.94 0.24
112 INT225098 ZNF630 Regulation of Localization of TGFB1 1 0.01 0.44 0.24
113 INT225105 ZNF630 Regulation of TGFB1 1 0.01 0.44 0.24
114 INT156881 TP53 Positive_regulation of Positive_regulation of PDF 1 0.49 0.89 0.24
115 INT9720 Binding of TGFB1 and Egf 1 0.01 0 0.23
116 INT168710 Ifng Regulation of TGFB1 1 0.00 0.3 0.23
117 INT229177 IFRD1 Regulation of TP53 1 0.13 0.68 0.23
118 INT112596 Tgfb1 Negative_regulation of Negative_regulation of Mptp1 1 0.26 0.72 0.22
119 INT226902 Padi3 Regulation of Trp53 1 0.06 0.69 0.22
120 INT112595 Tgfb1 Negative_regulation of Gene_expression of Mptp1 1 0.27 0.72 0.22
121 INT89475 TGFB1 Positive_regulation of Gene_expression of PTHLH 3 0.61 3.64 0.21
122 INT229178 TP53 Regulation of ICAM1 1 0.07 0.9 0.21
123 INT156882 Binding of TP53 and PDF 1 0.39 0.77 0.21
124 INT346458 ROS1 Regulation of Localization of TGFB1 1 0.00 1.71 0.21
125 INT114905 TGFB1 Positive_regulation of Transcription of COL7A1 1 0.02 0.08 0.21
126 INT156880 TP53 Positive_regulation of Gene_expression of PDF 1 0.49 0.75 0.21
127 INT92691 Tgfb1 Positive_regulation of Ctgf 1 0.16 0.91 0.2
128 INT92692 Tgfb1 Positive_regulation of Gene_expression of Fn1 1 0.27 0.91 0.2
129 INT210887 Sst Positive_regulation of Gene_expression of Trp53 1 0.33 0.93 0.2
130 INT92693 Tgfb1 Positive_regulation of Fgf2 1 0.32 0.9 0.2
131 INT126944 Binding of PKD2 and Pkd1 2 0.08 2.09 0.19
132 INT280260 Tgfb1 Positive_regulation of Cxcr1 1 0.07 1.78 0.19
133 INT280270 Tgfb1 Positive_regulation of Gene_expression of Cxcr4 1 0.08 1.81 0.19
134 INT92694 Tgfb1 Positive_regulation of Positive_regulation of Col3a1 1 0.31 0.89 0.19
135 INT280275 Tgfb1 Positive_regulation of VEGFA 1 0.02 2.46 0.19
136 INT153457 Tgfb1 Positive_regulation of Gene_expression of Ctgf 1 0.13 1.15 0.19
137 INT280268 Tgfb1 Positive_regulation of Gene_expression of Vegfa 1 0.06 1.81 0.19
138 INT280266 Tgfb1 Positive_regulation of Vegfa 1 0.09 1.8 0.19
139 INT280261 Tgfb1 Positive_regulation of Gene_expression of Cxcr1 1 0.05 1.81 0.19
140 INT193787 Positive_regulation of CXCR4 Positive_regulation of Positive_regulation of TP53 1 0.03 0.71 0.19
141 INT142853 Binding of TP53 and WISP2 1 0.33 1.43 0.19
142 INT280267 Tgfb1 Positive_regulation of Cxcr4 1 0.11 2.45 0.19
143 INT280274 Tgfb1 Positive_regulation of Gene_expression of VEGFA 1 0.02 2.58 0.19
144 INT350718 Mir106b Regulation of TGFB1 1 0.00 0.42 0.18
145 INT350603 MIR25 Regulation of TGFB1 1 0.01 0.42 0.18
146 INT271451 TGFB1 Regulation of Serpine1 1 0.00 0.68 0.18
147 INT224680 Tgfb1 Negative_regulation of Pten 1 0.00 1.19 0.18
148 INT85334 Agtr2 Regulation of Regulation of Tgfb1 1 0.23 0.68 0.17
149 INT102804 NFKB1 Regulation of TP53 1 0.35 0.77 0.17
150 INT102803 NFKB1 Regulation of Gene_expression of TP53 1 0.35 0.77 0.17
151 INT296037 TGFB1 Positive_regulation of IL17A 1 0.02 0 0.17
152 INT91812 Binding of FASLG and TP53 1 0.04 1.1 0.16
153 INT91811 Binding of FAS and TP53 1 0.21 1.1 0.16
154 INT160083 TGFB1 Positive_regulation of Gene_expression of L1CAM 1 0.16 1.53 0.16
155 INT136855 Arf5 Positive_regulation of Cdkn2a 1 0.07 1.8 0.15
156 INT266377 Binding of S100a11 and Trp53 1 0.02 0.89 0.15
157 INT85333 Aqp1 Positive_regulation of Negative_regulation of Tgfb1 1 0.25 0.67 0.15
158 INT314856 Binding of Cdc7 and Cdkn2a 1 0.28 1.34 0.14
159 INT302146 CDKN2A Regulation of CDKN1B 1 0.11 0.51 0.14
160 INT311666 Binding of BCL2 and TP53 1 0.19 1.26 0.14
161 INT353451 Binding of BRCA1 and CRP 1 0.01 1.18 0.14
162 INT302144 CDKN2A Regulation of CDKN1A 1 0.11 0.51 0.14
163 INT239323 Binding of Nr1h2 and Positive_regulation of Positive_regulation of Tgfb1 1 0.00 3.71 0.14
164 INT299550 TGFB1 Negative_regulation of Glul 1 0.01 0.34 0.14
165 INT314852 Binding of Cdkn2a and Tgfbr3 1 0.28 1.15 0.14
166 INT353453 Binding of BRCA1 and IL4 1 0.00 1.18 0.14
167 INT103557 Binding of ERCC2 and TP53 1 0.40 1 0.13
168 INT254855 Agt Positive_regulation of Tgfb1 1 0.03 0.18 0.13
169 INT296031 Negative_regulation of TGFB1 Regulation of IL10 1 0.01 1.01 0.13
170 INT132148 LTF Positive_regulation of TP53 1 0.44 0.56 0.13
171 INT296027 TGFB1 Regulation of TH1L 1 0.02 1 0.13
172 INT103561 Binding of TP53 and Mc1r 1 0.03 1 0.13
173 INT342311 Binding of Tp53 and Positive_regulation of Gene_expression of BCL2 1 0.08 1.25 0.13
174 INT299547 Negative_regulation of Binding of TGFB1 and Egf 1 0.02 0.1 0.13
175 INT69687 Tgfb1 Positive_regulation of Gene_expression of Il4 1 0.23 0 0.12
176 INT296080 TGFB1 Regulation of Hand2 1 0.01 1 0.12
177 INT331612 ETV4 Positive_regulation of Gene_expression of TGFB1 1 0.00 1.32 0.12
178 INT296028 TGFB1 Regulation of IL10 1 0.01 1 0.12
179 INT69688 Tgfb1 Positive_regulation of Rel 1 0.50 0 0.12
180 INT283719 Id2 Regulation of Regulation of Hes7 1 0.00 0.31 0.12
181 INT83370 Binding of HRAS and TP53 1 0.30 0.59 0.11
182 INT296038 TGFB1 Positive_regulation of Gene_expression of IL23R 1 0.02 0.05 0.11
183 INT299551 Regulation of Binding of TGFB1 and Egf 1 0.03 0.21 0.11
184 INT283710 Binding of Id2 and Hes7 1 0.01 0.13 0.11
185 INT300313 TGFB1 Positive_regulation of Mapk14 1 0.01 1.5 0.11
186 INT266386 Binding of S100a1 and Trp53 1 0.03 0.64 0.1
187 INT193782 Binding of TP53 and SDF2L1 1 0.00 0.67 0.1
188 INT262522 Binding of Trp53 and Foxo4 1 0.05 0.7 0.1
189 INT269788 Binding of FN1 and TGFB1 1 0.00 0.29 0.1
190 INT310743 TP53 Regulation of BAX 1 0.09 1.11 0.1
191 INT57220 Positive_regulation of ATF3 Positive_regulation of PRKACA 1 0.17 0.1 0.09
192 INT57214 ATF3 Positive_regulation of PRKACA 1 0.17 0.1 0.09
193 INT299555 Lifr Positive_regulation of Gene_expression of TGFB1 1 0.03 0.23 0.09
194 INT326126 Binding of S100A1 and TP53 1 0.04 1.34 0.09
195 INT352611 Trp53 Negative_regulation of Localization of Gli1 1 0.23 1.2 0.09
196 INT116789 Bsg Positive_regulation of Gene_expression of Tgfb1 1 0.00 0.18 0.09
197 INT302168 YWHAQ Regulation of TP53 1 0.01 0.41 0.09
198 INT265466 CSPG4 Regulation of Phosphorylation of TP53 1 0.09 0.15 0.09
199 INT127143 Binding of IL6 and TGFB1 2 0.01 0.16 0.08
200 INT246625 Sirt1 Positive_regulation of Negative_regulation of Trp53 1 0.10 0.96 0.08

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of cell cycle arrest. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of cell cycle arrest. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
2 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
3 INT48202 Gene_expression of Tgfb1 146 0.78 89.93 27.76
4 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23
5 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2
6 INT12081 Localization of TGFB1 64 0.81 35.4 17.47
7 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71
8 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
9 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
10 INT36336 Gene_expression of Tgfb1 41 0.77 21.82 14.53
11 INT94774 Regulation of CDKN2A 43 0.60 44.41 13.99
12 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61
13 INT48203 Positive_regulation of Tgfb1 67 0.70 41.31 11.07
14 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
15 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49
16 INT92138 Binding of CDKN2A 28 0.37 25.64 7.47
17 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25
18 INT61120 Positive_regulation of Gene_expression of Tgfb1 34 0.70 21.15 6.93
19 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24
20 INT112545 Phosphorylation of TP53 28 0.80 14.13 5.93
21 INT125467 Positive_regulation of Gene_expression of CDKN2A 35 0.63 39.07 5.56
22 INT48201 Localization of Tgfb1 27 0.59 13.65 5.54
23 INT13295 Positive_regulation of Cdkn2a 18 0.68 13.02 5.47
24 INT89794 Positive_regulation of CDKN2A 58 0.67 50.18 5.38
25 INT48200 Transcription of Tgfb1 13 0.69 3.85 5.24
26 INT60585 Regulation of TP53 59 0.59 54.55 5.21
27 INT67868 Negative_regulation of Gene_expression of Tgfb1 18 0.43 14.27 5.16
28 INT89104 Binding of TGFB1 29 0.44 13.67 5.12
29 INT109972 Phosphorylation of Trp53 13 0.80 6.15 4.68
30 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62
31 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45
32 INT89103 Regulation of Gene_expression of TGFB1 15 0.56 8.11 4.37
33 INT119063 Gene_expression of BRCA1 24 0.67 30.04 4.17
34 INT36335 Localization of Tgfb1 19 0.79 7.06 4.17
35 INT69681 Negative_regulation of Tgfb1 42 0.51 22.28 4
36 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68
37 INT12083 Regulation of TGFB1 22 0.53 15.4 3.6
38 INT51848 Transcription of TGFB1 17 0.69 9.57 3.53
39 INT56300 Negative_regulation of Gene_expression of TGFB1 13 0.41 4.87 3.5
40 INT69216 Positive_regulation of Tgfb1 14 0.49 5.84 3.29
41 INT78471 Regulation of Gene_expression of CDKN2A 13 0.45 12.52 3.28
42 INT85147 Positive_regulation of Gene_expression of Tgfb1 12 0.46 7.29 3.24
43 INT85149 Negative_regulation of Gene_expression of Tgfb1 11 0.42 4.73 3.19
44 INT34977 Gene_expression of Hmga2 11 0.76 12.39 3.07
45 INT112667 Negative_regulation of Tgfb1 9 0.58 2.72 2.97
46 INT8103 Binding of TP53 46 0.44 40.2 2.96
47 INT9130 Negative_regulation of TGFB1 16 0.41 12.21 2.92
48 INT78248 Negative_regulation of Cdkn2a 17 0.59 15.15 2.8
49 INT48199 Regulation of Tgfb1 17 0.54 9.57 2.74
50 INT221269 Binding of BRCA1 14 0.40 31.77 2.7
51 INT101246 Gene_expression of Gata6 6 0.68 3.03 2.68
52 INT109969 Positive_regulation of Phosphorylation of Trp53 1 0.45 2.18 2.66
53 INT109968 Positive_regulation of Positive_regulation of Trp53 6 0.47 3.57 2.51
54 INT92141 Negative_regulation of CDKN2A 53 0.57 44.23 2.48
55 INT48198 Binding of Tgfb1 29 0.47 19.59 2.46
56 INT338170 Regulation of Regulation of CDKN2A 1 0.44 0.96 2.46
57 INT55952 Transcription of TP53 16 0.61 12.14 2.36
58 INT12086 Regulation of Localization of TGFB1 4 0.43 1.65 2.09
59 INT94772 Gene_expression of Cdkn2a 14 0.75 8.25 2.04
60 INT125080 Positive_regulation of Positive_regulation of TP53 21 0.58 16.16 1.98
61 INT146793 Positive_regulation of Tp53 30 0.70 32.93 1.94
62 INT65855 Localization of TP53 18 0.76 17.08 1.89
63 INT74824 Positive_regulation of Transcription of TGFB1 6 0.67 2.58 1.84
64 INT113345 Positive_regulation of Phosphorylation of TP53 8 0.66 6.11 1.8
65 INT101252 Negative_regulation of Gene_expression of Gata6 1 0.51 1.3 1.74
66 INT101244 Regulation of Gata6 3 0.40 1.52 1.7
67 INT129610 Gene_expression of Id2 7 0.74 17.07 1.69
68 INT86712 Regulation of Gene_expression of Tgfb1 2 0.15 2.03 1.65
69 INT84310 Regulation of Gene_expression of Tgfb1 7 0.29 6.6 1.63
70 INT120071 Negative_regulation of Positive_regulation of Tgfb1 4 0.16 4.06 1.55
71 INT64233 Regulation of Trp53 35 0.62 27.11 1.53
72 INT221422 Positive_regulation of BRCA1 5 0.23 12.63 1.53
73 INT110992 Positive_regulation of Positive_regulation of TGFB1 4 0.50 3.01 1.51
74 INT120004 Transcription of Tp53 8 0.72 4.92 1.48
75 INT101990 Negative_regulation of Positive_regulation of TP53 5 0.33 3.69 1.42
76 INT162469 Positive_regulation of Protein_catabolism of TP53 5 0.52 5.48 1.42
77 INT228040 Negative_regulation of Transcription of Tgfb1 1 0.04 0.49 1.42
78 INT172953 Binding of Trp53 33 0.37 20.76 1.41
79 INT93357 Regulation of Gene_expression of Trp53 15 0.62 13.4 1.41
80 INT162462 Protein_catabolism of TP53 8 0.86 7.89 1.41
81 INT12085 Positive_regulation of Localization of TGFB1 7 0.42 4.9 1.4
82 INT78470 Negative_regulation of Gene_expression of CDKN2A 14 0.59 14.44 1.38
83 INT145221 Binding of Tp53 10 0.37 8.59 1.37
84 INT119062 Negative_regulation of BRCA1 12 0.49 13.7 1.36
85 INT173892 Phosphorylation of TGFB1 8 0.79 2.63 1.3
86 INT174156 Localization of Trp53 16 0.72 13.52 1.18
87 INT116436 Negative_regulation of Phosphorylation of TP53 2 0.40 0.94 1.16
88 INT134661 Negative_regulation of Tp53 11 0.43 10.91 1.13
89 INT42104 Regulation of Cdkn2a 4 0.44 5.67 1.06
90 INT120858 Positive_regulation of Localization of Tgfb1 7 0.68 1.46 1.03
91 INT97052 Transcription of Trp53 12 0.64 6.52 1.01
92 INT34978 Negative_regulation of Gene_expression of Hmga2 2 0.42 1.53 0.95
93 INT128717 Regulation of Tgfb1 6 0.61 1.94 0.94
94 INT123852 Negative_regulation of Positive_regulation of Tgfb1 3 0.28 1.69 0.94
95 INT338168 Positive_regulation of Binding of CDKN2A 1 0.49 0.52 0.94
96 INT139322 Negative_regulation of Negative_regulation of Tgfb1 1 0.53 0 0.86
97 INT101248 Negative_regulation of Gata6 1 0.37 0.83 0.85
98 INT101251 Negative_regulation of Positive_regulation of Gata6 1 0.38 0.83 0.85
99 INT85148 Transcription of Tgfb1 5 0.52 1.91 0.84
100 INT101250 Positive_regulation of Gata6 1 0.41 0.83 0.84
101 INT102848 Negative_regulation of Localization of Tgfb1 3 0.10 1.81 0.83
102 INT101245 Transcription of Gata6 2 0.47 0.85 0.82
103 INT93356 Negative_regulation of Gene_expression of Trp53 28 0.53 20.61 0.8
104 INT139323 Positive_regulation of Negative_regulation of Tgfb1 1 0.45 0 0.79
105 INT144429 Positive_regulation of Cdkn2a 7 0.58 4.05 0.78
106 INT129115 Negative_regulation of Cdkn2a 16 0.50 17.03 0.76
107 INT291617 Negative_regulation of Transcription of TGFB1 2 0.15 0.61 0.76
108 INT102813 Regulation of Gene_expression of TP53 25 0.59 25.95 0.75
109 INT168245 Positive_regulation of Transcription of Tp53 2 0.70 2.63 0.75
110 INT90790 Regulation of Localization of Tgfb1 2 0.29 0.46 0.75
111 INT162470 Negative_regulation of Protein_catabolism of TP53 1 0.32 1.24 0.74
112 INT337046 Positive_regulation of Binding of Tgfb1 1 0.30 1.1 0.69
113 INT121302 Positive_regulation of Localization of Tgfb1 5 0.07 1.91 0.67
114 INT114909 Negative_regulation of Localization of TGFB1 5 0.36 1.37 0.66
115 INT353152 Localization of PRKACA 1 0.01 1.15 0.66
116 INT88987 Gene_expression of HMGA2 8 0.77 10.46 0.64
117 INT111891 Regulation of Transcription of Tgfb1 1 0.04 0.68 0.64
118 INT137850 Gene_expression of PKD2 9 0.65 6.68 0.63
119 INT251026 Negative_regulation of Phosphorylation of CDKN2A 5 0.42 5.02 0.62
120 INT177886 Positive_regulation of Gene_expression of Cdkn2a 3 0.67 3.42 0.62
121 INT93358 Negative_regulation of Positive_regulation of Trp53 9 0.41 3.95 0.6
122 INT53950 Phosphorylation of Tp53 8 0.61 9.4 0.6
123 INT114910 Negative_regulation of Positive_regulation of TGFB1 3 0.34 0.92 0.6
124 INT173891 Positive_regulation of Phosphorylation of TGFB1 4 0.49 2 0.59
125 INT147598 Negative_regulation of Positive_regulation of CDKN2A 3 0.41 1.47 0.59
126 INT138140 Protein_catabolism of Tgfb1 2 0.09 0.87 0.59
127 INT129615 Positive_regulation of Id2 2 0.66 2.22 0.57
128 INT221420 Positive_regulation of Gene_expression of BRCA1 2 0.24 2.17 0.55
129 INT242011 Localization of Cdkn2a 4 0.73 2.49 0.54
130 INT144701 Gene_expression of Cdkn2a 15 0.75 8.42 0.53
131 INT69683 Positive_regulation of Transcription of Tgfb1 1 0.67 0 0.53
132 INT144431 Positive_regulation of Transcription of Cdkn2a 1 0.41 1.11 0.51
133 INT144426 Transcription of Cdkn2a 1 0.42 1.11 0.51
134 INT142972 Gene_expression of ID2 6 0.54 5.92 0.49
135 INT286035 Negative_regulation of Gene_expression of Tp53 5 0.32 6.2 0.49
136 INT88170 Positive_regulation of HMGA2 2 0.69 2 0.48
137 INT220088 Positive_regulation of Positive_regulation of CDKN2A 4 0.49 4.04 0.44
138 INT252657 Positive_regulation of Phosphorylation of CDKN2A 2 0.45 3.09 0.42
139 INT42105 Regulation of Positive_regulation of Cdkn2a 1 0.44 0.33 0.42
140 INT139976 Regulation of Tp53 7 0.44 6.49 0.39
141 INT145220 Negative_regulation of Binding of Tp53 1 0.20 0.75 0.36
142 INT283683 Binding of Id2 5 0.35 0.8 0.35
143 INT69680 Positive_regulation of Positive_regulation of Tgfb1 3 0.67 1.04 0.35
144 INT88167 Negative_regulation of Positive_regulation of HMGA2 1 0.41 0.16 0.35
145 INT353457 Positive_regulation of Binding of BRCA1 1 0.09 1.69 0.34
146 INT196323 Localization of Cdkn2a 8 0.73 9.1 0.32
147 INT251025 Phosphorylation of CDKN2A 4 0.61 3.19 0.32
148 INT221419 Regulation of BRCA1 5 0.35 6.18 0.31
149 INT93355 Negative_regulation of Negative_regulation of Trp53 2 0.41 0.92 0.3
150 INT179089 Protein_catabolism of Trp53 8 0.90 6.52 0.29
151 INT228477 Positive_regulation of Gene_expression of Cdkn2a 2 0.11 1.3 0.29
152 INT88988 Positive_regulation of Gene_expression of HMGA2 1 0.69 4.05 0.29
153 INT196937 Positive_regulation of Hmga2 3 0.68 2.47 0.28
154 INT166960 Positive_regulation of Negative_regulation of TP53 2 0.25 1.65 0.26
155 INT184624 Localization of CDKN2A 8 0.74 7.87 0.25
156 INT314729 Regulation of Localization of TP53 1 0.30 2.5 0.25
157 INT238494 Regulation of Transcription of CDKN2A 1 0.16 5.62 0.25
158 INT251228 Phosphorylation of Tgfb1 4 0.15 1.18 0.24
159 INT179088 Positive_regulation of Regulation of Trp53 3 0.38 3.23 0.23
160 INT48785 Gene_expression of PRKACA 1 0.35 0 0.23
161 INT156886 Positive_regulation of Localization of TP53 1 0.48 0.87 0.23
162 INT129612 Positive_regulation of Gene_expression of Id2 4 0.67 3.61 0.22
163 INT299545 Positive_regulation of Binding of TGFB1 2 0.06 1.08 0.22
164 INT221268 Localization of BRCA1 7 0.63 4.83 0.18
165 INT241687 Binding of Cdkn2a 5 0.31 5.26 0.18
166 INT119061 Negative_regulation of Gene_expression of BRCA1 4 0.51 0.85 0.18
167 INT89689 Binding of Brca1 2 0.37 2.55 0.18
168 INT85330 Positive_regulation of Regulation of Tgfb1 1 0.41 0.67 0.17
169 INT300284 Regulation of Phosphorylation of Tp53 1 0.16 1.51 0.17
170 INT122201 Binding of Tgfb1 1 0.16 0.17 0.17
171 INT337078 Negative_regulation of Localization of Trp53 1 0.20 1.3 0.17
172 INT147149 Transcription of CDKN2A 8 0.67 6.85 0.15
173 INT179086 Positive_regulation of Negative_regulation of Trp53 5 0.50 4.78 0.15
174 INT125081 Positive_regulation of Binding of TP53 2 0.46 1.2 0.15
175 INT207805 Negative_regulation of Phosphorylation of Trp53 2 0.18 0.98 0.15
176 INT133100 Negative_regulation of Localization of Tgfb1 2 0.28 1.48 0.15
177 INT286749 Regulation of Localization of Trp53 1 0.06 1.39 0.15
178 INT225216 Negative_regulation of Negative_regulation of Cdkn2a 1 0.42 3.16 0.15
179 INT168244 Regulation of Transcription of Tp53 1 0.33 0.57 0.13
180 INT283702 Transcription of Id2 1 0.66 0.64 0.13
181 INT187590 Gene_expression of Brca1 12 0.65 4.94 0.11
182 INT283708 Localization of Id2 2 0.71 0.72 0.11
183 INT142970 Positive_regulation of Gene_expression of ID2 2 0.40 2.39 0.11
184 INT142968 Negative_regulation of Gene_expression of ID2 1 0.19 0.98 0.11
185 INT208914 Regulation of Brca1 1 0.10 0.79 0.11
186 INT112001 Binding of Cdkn2a 1 0.24 0.35 0.1
187 INT297456 Protein_catabolism of Tp53 1 0.11 0.72 0.1
188 INT111139 Localization of Tp53 4 0.45 2.4 0.09
189 INT14738 Negative_regulation of Regulation of TGFB1 2 0.41 0.81 0.09
190 INT142971 Negative_regulation of Positive_regulation of ID2 1 0.20 0.69 0.09
191 INT142969 Positive_regulation of ID2 1 0.21 0.68 0.09
192 INT273604 Regulation of Negative_regulation of Cdkn2a 1 0.12 0.68 0.09
193 INT170298 Regulation of Gene_expression of Hmga2 1 0.01 0.48 0.08
194 INT129614 Positive_regulation of Positive_regulation of Id2 1 0.48 0.31 0.08
195 INT331623 Negative_regulation of Binding of TGFB1 1 0.02 1.02 0.08
196 INT174155 Negative_regulation of Brca1 4 0.36 1.77 0.07
197 INT352605 Regulation of Negative_regulation of Trp53 1 0.45 0.72 0.07
198 INT88990 Binding of HMGA2 1 0.48 0.95 0.07
199 INT170300 Positive_regulation of Gene_expression of Hmga2 2 0.68 4.51 0.06
200 INT170302 Regulation of Hmga2 2 0.44 0.94 0.06
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