GO:0071229

From wiki-pain
Jump to: navigation, search
Name cellular response to acid
Categary Process
Go Slim No
Go Link GO:0071229
Unique Molecular Interactions 62
Total Molecular Interactions 109
Total Single Events 328
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cellular response to acid. They are ordered first by their pain relevance and then by number of times they were reported for cellular response to acid. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT346204 Binding of S100A10 and TPPP 1 0.02 1.62 0.97
2 INT128860 NR1H4 Negative_regulation of Gene_expression of OPRM1 1 0.15 0.31 0.92
3 INT284855 Binding of S100a10 and Nav1 4 0.21 0.99 0.88
4 INT130138 TNF Negative_regulation of Gene_expression of S100A10 1 0.06 1.32 0.78
5 INT177269 Binding of CXADR and NR1H4 1 0.04 0 0.58
6 INT114676 Mdm2 Negative_regulation of p53-ps 1 0.10 0.26 0.48
7 INT130137 TNF Positive_regulation of Positive_regulation of S100A10 1 0.07 0.62 0.47
8 INT321293 Binding of Nr1h4 and Nr0b2 1 0.18 0.31 0.43
9 INT262189 Binding of Nr1i2 and Nr1h4 1 0.14 0.18 0.36
10 INT262218 Nr1h4 Regulation of Nr1i2 1 0.10 0.15 0.34
11 INT262144 Nr1h4 Positive_regulation of Positive_regulation of Nr1i2 1 0.19 0.19 0.27
12 INT262227 Nr1h4 Regulation of Transcription of CYP3A4 1 0.08 0.12 0.26
13 INT262180 Nr1h4 Regulation of Sult2a1 1 0.11 0.11 0.25
14 INT262152 Nr1h4 Regulation of Abcc2 1 0.07 0.12 0.25
15 INT173120 Binding of PPARA and NR1H4 8 0.09 2.79 0.23
16 INT262211 Nr1h4 Negative_regulation of Gene_expression of Cyp7a1 1 0.09 0.14 0.23
17 INT344714 Nr1h4 Negative_regulation of Gene_expression of Lipg 1 0.02 0.77 0.23
18 INT262159 Positive_regulation of Nr1h4 Negative_regulation of Gene_expression of Cyp7a1 1 0.09 0.14 0.23
19 INT321290 Positive_regulation of Nr1h4 Positive_regulation of Nr0b2 1 0.20 0.2 0.18
20 INT284857 S100a10 Positive_regulation of Gene_expression of Nav1 1 0.16 0.3 0.17
21 INT284861 S100a10 Positive_regulation of Localization of Nav1 1 0.17 0.07 0.14
22 INT278610 CDCA2 Negative_regulation of NR1H4 1 0.01 0.62 0.13
23 INT264403 NR1H4 Negative_regulation of IL1R2 1 0.04 0.09 0.12
24 INT284853 Binding of S100a10 and Pdzd2 1 0.21 0.08 0.09
25 INT177263 Binding of NR1H4 and FAUP1 1 0.00 0 0.09
26 INT177278 Binding of HLA-DRB4 and NR1H4 1 0.02 0 0.08
27 INT279416 NR1H4 Regulation of PPARA 1 0.01 0.13 0.08
28 INT177265 Binding of CYP3A4 and NR1H4 1 0.03 0 0.08
29 INT279421 Binding of NR1H4 and MLXIPL 1 0.00 0.27 0.07
30 INT177255 Binding of SV2A and NR1H4 1 0.04 0 0.07
31 INT182943 Binding of DR1 and NR1H4 3 0.03 0.14 0.06
32 INT242475 Ciapin1 Positive_regulation of Gene_expression of Anxa2 1 0.01 1.13 0.06
33 INT113862 Binding of CA2 and NR1H4 1 0.00 0 0.06
34 INT113861 Binding of CA3 and NR1H4 1 0.00 0 0.06
35 INT177276 Positive_regulation of Binding of CXADR and NR1H4 1 0.04 0 0.05
36 INT177282 Regulation of Binding of CXADR and NR1H4 1 0.02 0 0.05
37 INT177270 Binding of TNFRSF25 and NR1H4 2 0.02 0.21 0.04
38 INT177272 Binding of ABCB1 and NR1H4 1 0.02 0 0.04
39 INT256418 PPARA Positive_regulation of NR1H4 1 0.01 1.17 0.04
40 INT264382 NR1H4 Positive_regulation of VDR 1 0.04 0.09 0.03
41 INT264396 NR1H4 Positive_regulation of THRA 1 0.01 0.09 0.03
42 INT182950 Binding of VDR and NR1H4 5 0.03 1.16 0
43 INT182924 Binding of RARA and NR1H4 3 0.02 1.9 0
44 INT290033 Binding of PPARD and NR1H4 1 0.01 0.39 0
45 INT290027 Binding of PPARG and NR1H4 1 0.03 0.39 0
46 INT290029 Binding of INS and NR1H4 1 0.01 0.47 0
47 INT180855 TGFB1 Regulation of S100A10 1 0.06 0.69 0
48 INT180862 Binding of ANXA2 and S100A10 1 0.17 0.82 0
49 INT324567 S100a10 Positive_regulation of Gene_expression of Kiss1 1 0.28 0 0
50 INT183014 Binding of NR1H4 and Dre 1 0.00 0.06 0
51 INT182955 Positive_regulation of Binding of VDR and NR1H4 1 0.03 0 0
52 INT302303 Binding of NR1H4 and Rdh5 1 0.02 0.11 0
53 INT330956 Binding of TEP1 and NR1H4 1 0.00 1.07 0
54 INT180853 Binding of PLA2G1B and S100A10 1 0.08 0.75 0
55 INT180865 TGFB1 Positive_regulation of S100A10 1 0.24 1.22 0
56 INT234439 Binding of NR1H4 and HCC 1 0.06 0.82 0
57 INT278605 CDCA2 Positive_regulation of NR1H4 1 0.01 0.36 0
58 INT182930 Binding of TNFRSF10B and NR1H4 1 0.02 0 0
59 INT135128 Binding of NR1I2 and NR1H4 1 0.09 0.57 0
60 INT180850 TGFB1 Regulation of Gene_expression of S100A10 1 0.24 0.7 0
61 INT182963 Binding of NR1H4 and KCNIP3 1 0.03 0.45 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cellular response to acid. They are ordered first by their pain relevance and then by number of times they were reported in cellular response to acid. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT114674 Gene_expression of Mdm2 15 0.78 3.51 11.85
2 INT114675 Positive_regulation of Gene_expression of Mdm2 1 0.70 1.98 7.9
3 INT346212 Binding of S100A10 1 0.09 5.7 3.23
4 INT132575 Binding of NR1H4 57 0.20 22.06 2.82
5 INT321310 Positive_regulation of Nr1h4 1 0.49 1.75 2.75
6 INT169073 Positive_regulation of Nr1h4 8 0.47 2.44 2.45
7 INT169072 Gene_expression of Nr1h4 7 0.60 6.23 2.18
8 INT114953 Gene_expression of NR1H4 23 0.29 16.58 2.02
9 INT139247 Gene_expression of S100a10 13 0.67 2.35 1.57
10 INT130143 Gene_expression of S100A10 5 0.68 6.48 1.47
11 INT166917 Positive_regulation of S100a10 3 0.69 1.47 1.45
12 INT135132 Positive_regulation of NR1H4 17 0.30 8.63 1.38
13 INT114671 Positive_regulation of Mdm2 1 0.61 0.5 1.38
14 INT133255 Gene_expression of Anxa2 8 0.41 8.52 1.3
15 INT114961 Positive_regulation of Gene_expression of NR1H4 6 0.16 3.55 1.23
16 INT321329 Positive_regulation of Positive_regulation of Nr1h4 1 0.35 0.43 1.07
17 INT114673 Regulation of Gene_expression of Mdm2 1 0.62 0.23 1.02
18 INT284852 Binding of S100a10 4 0.26 1.58 0.78
19 INT139249 Negative_regulation of S100a10 4 0.42 1.21 0.75
20 INT180891 Regulation of S100A10 2 0.54 2.52 0.7
21 INT262091 Negative_regulation of Nr1h4 1 0.15 0.76 0.68
22 INT284850 Regulation of S100a10 2 0.32 1.04 0.67
23 INT130139 Negative_regulation of Gene_expression of S100A10 2 0.38 1.43 0.47
24 INT130142 Positive_regulation of S100A10 2 0.41 1.34 0.47
25 INT262102 Binding of Nr1h4 1 0.13 0.34 0.43
26 INT234463 Phosphorylation of NR1H4 23 0.34 14.56 0.39
27 INT203309 Regulation of Anxa2 1 0.42 1.03 0.35
28 INT234456 Negative_regulation of Gene_expression of NR1H4 2 0.18 1.05 0.32
29 INT284851 Positive_regulation of Gene_expression of S100a10 2 0.25 0.73 0.27
30 INT262108 Negative_regulation of Positive_regulation of Nr1h4 1 0.15 0.14 0.22
31 INT101226 Binding of Anxa2 3 0.05 0 0.2
32 INT321313 Regulation of Nr1h4 1 0.32 0.37 0.17
33 INT234469 Negative_regulation of Phosphorylation of NR1H4 2 0.14 1.25 0.16
34 INT112614 Positive_regulation of ANXA2 1 0.59 0.09 0.14
35 INT234464 Negative_regulation of NR1H4 6 0.19 3.54 0.12
36 INT234468 Protein_catabolism of NR1H4 2 0.32 0.87 0.09
37 INT177318 Negative_regulation of Binding of NR1H4 5 0.14 3.39 0.08
38 INT168505 Localization of S100A10 2 0.58 2.03 0.08
39 INT234477 Localization of NR1H4 3 0.24 2.23 0.07
40 INT321327 Transcription of Nr1h4 1 0.50 0.15 0.07
41 INT133256 Transcription of Anxa2 1 0.04 1.5 0.07
42 INT321330 Negative_regulation of Transcription of Nr1h4 1 0.30 0.15 0.07
43 INT206951 Gene_expression of Nr1h4 2 0.56 0.68 0.03
44 INT321312 Phosphorylation of Nr1h4 1 0.58 0.23 0.03
45 INT272372 Negative_regulation of Gene_expression of S100a10 1 0.06 0 0.03
46 INT321351 Positive_regulation of Gene_expression of Nr1h4 1 0.49 0.12 0.03
47 INT79328 Negative_regulation of S100A10 3 0.38 0.77 0
48 INT177301 Positive_regulation of Binding of NR1H4 3 0.29 0.45 0
49 INT234451 Positive_regulation of Phosphorylation of NR1H4 1 0.22 5.15 0
50 INT180901 Positive_regulation of Negative_regulation of S100A10 1 0.44 0.78 0
51 INT234475 Transcription of NR1H4 1 0.17 1.62 0
52 INT330707 Localization of Anxa2 1 0.02 1.13 0
53 INT166918 Localization of S100a10 1 0.79 0.08 0
54 INT234470 Positive_regulation of Protein_catabolism of NR1H4 1 0.22 0.93 0
55 INT337996 Transcription of S100a10 1 0.44 0.83 0
56 INT264439 Regulation of Binding of NR1H4 1 0.19 0 0
57 INT272371 Negative_regulation of Positive_regulation of S100a10 1 0.05 0 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox