GO:0071280

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Name cellular response to copper ion
Categary Process
Go Slim No
Go Link GO:0071280
Unique Molecular Interactions 40
Total Molecular Interactions 50
Total Single Events 832
Pain Genes Associated 11

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cellular response to copper ion. They are ordered first by their pain relevance and then by number of times they were reported for cellular response to copper ion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT275850 Binding of NDUFAB1 and SNCA 1 0.00 3.78 3.16
2 INT342165 Binding of Aqp1 and Nav1 1 0.25 0.57 1.25
3 INT84603 Adrb1 Regulation of Gene_expression of Aqp2 1 0.00 0 0.56
4 INT309157 Aqp1 Positive_regulation of Bdnf 1 0.00 0.74 0.42
5 INT84600 Binding of Avp and Aqp2 1 0.17 0 0.35
6 INT190806 Ubd Regulation of Abp1 1 0.20 0.82 0.32
7 INT139778 Binding of AQP1 and GBE1 1 0.00 0.22 0.3
8 INT293118 Avp Regulation of Aqp2 1 0.04 0.7 0.27
9 INT58305 AQP1 Regulation of Localization of TNF 1 0.10 0.16 0.22
10 INT58303 AQP1 Regulation of Gene_expression of IL1B 1 0.10 0.16 0.22
11 INT342163 Nkx2-1 Regulation of Gene_expression of Aqp1 1 0.06 0.51 0.2
12 INT85333 Aqp1 Positive_regulation of Negative_regulation of Tgfb1 1 0.25 0.67 0.15
13 INT293124 Agtr1a Regulation of Gene_expression of Aqp2 1 0.17 0.36 0.14
14 INT327829 Aqp1 Regulation of Binding of Csf2 1 0.11 1 0.14
15 INT293117 Agt Regulation of Gene_expression of Aqp2 1 0.23 0.36 0.14
16 INT158141 Binding of HOXD13 and SNCA 1 0.54 0.41 0.11
17 INT83270 Snca Regulation of Napepld 1 0.14 0 0.09
18 INT38206 Acr Negative_regulation of Txnrd1 1 0.20 0.08 0.08
19 INT234802 Binding of AQP2 and AVPR2 2 0.15 0.84 0.07
20 INT293122 Avp Regulation of Gene_expression of Aqp2 1 0.04 0.81 0.05
21 INT241775 AVP Positive_regulation of Gene_expression of AQP2 1 0.08 0.17 0
22 INT297693 Binding of Aqp2 and Fut1 1 0.03 0 0
23 INT79900 NFE2L2 Positive_regulation of Gene_expression of AQP1 1 0.03 0 0
24 INT191276 Binding of ABP1 and LSS 1 0.17 0.68 0
25 INT262498 Binding of Aqp1 and Cav1 1 0.03 0.56 0
26 INT354080 Avpr2 Positive_regulation of Localization of Aqp2 1 0.02 0.07 0
27 INT293114 Fig4 Regulation of Gene_expression of Aqp2 1 0.08 1.53 0
28 INT234803 AVP Regulation of AQP2 1 0.11 1.3 0
29 INT98626 Aqp1 Positive_regulation of Aqp4 1 0.52 0 0
30 INT234796 Binding of AQP2 and AVP 1 0.15 1.1 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cellular response to copper ion. They are ordered first by their pain relevance and then by number of times they were reported in cellular response to copper ion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT104567 Gene_expression of Aqp1 47 0.78 44.84 28.68
2 INT104569 Gene_expression of Aqp2 23 0.60 16.56 12.23
3 INT327801 Positive_regulation of Gene_expression of Aqp2 6 0.44 7.67 7.24
4 INT156134 Regulation of Gene_expression of Aqp1 5 0.59 7.2 5.3
5 INT85328 Negative_regulation of Aqp1 5 0.54 6.02 4.94
6 INT79902 Gene_expression of AQP1 33 0.78 24.72 4.55
7 INT85326 Positive_regulation of Aqp1 7 0.65 5.9 3.71
8 INT817 Negative_regulation of Abp1 15 0.49 4.25 3.56
9 INT104570 Localization of Aqp1 8 0.77 5.83 3.51
10 INT119412 Gene_expression of Snca 15 0.66 11.27 3.39
11 INT110245 Gene_expression of SNCA 11 0.77 8.29 3.36
12 INT14106 Positive_regulation of Abp1 4 0.51 3.85 2.78
13 INT84599 Gene_expression of Aqp2 31 0.77 22.58 2.54
14 INT2611 Negative_regulation of AQP1 17 0.39 10.04 2.15
15 INT141721 Binding of Aqp1 5 0.37 1.77 2.15
16 INT203308 Regulation of Aqp1 4 0.48 2.59 2.13
17 INT84595 Negative_regulation of Aqp2 11 0.58 4.88 1.78
18 INT148266 Positive_regulation of SNCA 5 0.67 3.17 1.74
19 INT156133 Regulation of Gene_expression of Aqp2 4 0.39 1.43 1.53
20 INT72249 Negative_regulation of ABP1 6 0.36 1.08 1.41
21 INT211054 Positive_regulation of AQP1 3 0.33 4.53 1.41
22 INT327824 Positive_regulation of Gene_expression of Aqp1 4 0.67 5.4 1.37
23 INT72248 Binding of ABP1 7 0.29 4.33 1.36
24 INT73553 Gene_expression of Aqp1 23 0.67 4.65 1.34
25 INT100328 Gene_expression of AQP2 6 0.75 2.41 1.21
26 INT110244 Positive_regulation of Gene_expression of SNCA 5 0.69 4.66 1.19
27 INT79557 Localization of Aqp2 5 0.73 2 1.13
28 INT62440 Localization of Abp1 1 0.37 1.12 1.11
29 INT286344 Positive_regulation of Gene_expression of Snca 1 0.41 2.84 1.03
30 INT166889 Positive_regulation of Gene_expression of AQP1 10 0.70 6.43 0.99
31 INT84597 Transcription of Aqp2 3 0.55 2.11 0.98
32 INT183362 Regulation of AQP1 3 0.23 1.49 0.92
33 INT84598 Regulation of Aqp2 13 0.45 4.28 0.86
34 INT108348 Positive_regulation of Aqp2 10 0.68 4.94 0.82
35 INT149238 Positive_regulation of Gene_expression of Aqp2 5 0.66 3.07 0.73
36 INT327798 Transcription of Aqp2 1 0.34 1.02 0.72
37 INT241788 Positive_regulation of Gene_expression of AQP2 3 0.67 1.26 0.7
38 INT112326 Binding of Aqp2 3 0.11 1.01 0.69
39 INT84596 Negative_regulation of Gene_expression of Aqp2 3 0.58 8.49 0.6
40 INT84594 Negative_regulation of Transcription of Aqp2 1 0.43 0 0.59
41 INT100322 Localization of AQP2 5 0.80 0.56 0.56
42 INT139780 Binding of AQP1 7 0.32 4.62 0.54
43 INT191287 Positive_regulation of ABP1 6 0.39 3.72 0.51
44 INT19592 Localization of AQP1 4 0.81 1.09 0.44
45 INT327786 Negative_regulation of Gene_expression of AQP1 3 0.29 4.21 0.44
46 INT148264 Transcription of SNCA 1 0.40 0.25 0.42
47 INT191288 Gene_expression of ABP1 7 0.52 6.61 0.4
48 INT149235 Positive_regulation of Transcription of Aqp2 1 0.45 0.72 0.4
49 INT149244 Positive_regulation of Localization of Aqp2 1 0.49 0.72 0.4
50 INT343972 Negative_regulation of Binding of SNCA 1 0.36 0.2 0.39
51 INT100324 Regulation of Localization of AQP2 1 0.27 0.19 0.38
52 INT157836 Regulation of Gene_expression of Aqp2 9 0.57 8.37 0.37
53 INT203374 Positive_regulation of Regulation of Aqp1 2 0.36 0.91 0.37
54 INT169628 Binding of SNCA 4 0.47 3.53 0.36
55 INT73145 Binding of Abp1 2 0.07 0.17 0.36
56 INT100323 Regulation of Gene_expression of AQP2 1 0.45 0.18 0.36
57 INT38203 Negative_regulation of Txnrd1 4 0.39 0.27 0.35
58 INT79558 Binding of Aqp2 2 0.31 0.25 0.33
59 INT190805 Positive_regulation of Positive_regulation of Abp1 1 0.39 0.82 0.32
60 INT293551 Regulation of Positive_regulation of Aqp1 1 0.13 0 0.31
61 INT343973 Localization of SNCA 1 0.63 0.07 0.3
62 INT34827 Regulation of ABP1 1 0.62 0.24 0.29
63 INT190801 Gene_expression of Abp1 1 0.46 0.35 0.25
64 INT190803 Regulation of Abp1 1 0.42 0.33 0.23
65 INT142052 Binding of Snca 4 0.47 1.02 0.22
66 INT104568 Negative_regulation of Localization of Aqp1 1 0.36 2.47 0.2
67 INT215814 Negative_regulation of Gene_expression of Aqp1 2 0.31 0.25 0.17
68 INT98625 Regulation of Aqp1 1 0.27 0.1 0.17
69 INT166361 Phosphorylation of SNCA 1 0.70 0.72 0.17
70 INT157084 Localization of Snca 1 0.51 0.17 0.16
71 INT343974 Negative_regulation of Gene_expression of SNCA 1 0.31 0.09 0.16
72 INT286343 Negative_regulation of Gene_expression of Snca 1 0.26 0.65 0.15
73 INT350601 Regulation of Negative_regulation of ABP1 1 0.04 0.23 0.14
74 INT350602 Positive_regulation of Positive_regulation of ABP1 1 0.05 0.24 0.13
75 INT190800 Negative_regulation of Regulation of Abp1 1 0.29 0.19 0.12
76 INT67594 Protein_catabolism of Abp1 1 0.23 0.99 0.12
77 INT104566 Negative_regulation of Aqp2 3 0.44 1.23 0.11
78 INT190796 Negative_regulation of Gene_expression of Abp1 1 0.29 0.14 0.11
79 INT33738 Protein_catabolism of ABP1 1 0.62 0 0.11
80 INT215820 Negative_regulation of Aqp1 3 0.23 0.83 0.1
81 INT156816 Regulation of Txnrd1 1 0.22 0 0.1
82 INT159343 Positive_regulation of Localization of AQP1 1 0.11 0 0.1
83 INT111047 Negative_regulation of Gene_expression of Aqp2 3 0.34 3.56 0.09
84 INT157832 Phosphorylation of Aqp2 2 0.77 2.04 0.08
85 INT327827 Negative_regulation of Gene_expression of Aqp1 1 0.45 0.8 0.08
86 INT262510 Regulation of Gene_expression of Aqp1 1 0.33 1.18 0.07
87 INT255040 Positive_regulation of Gene_expression of ABP1 1 0.02 1.01 0.07
88 INT293110 Positive_regulation of Phosphorylation of Aqp2 1 0.47 1.39 0.05
89 INT293105 Positive_regulation of Positive_regulation of Aqp2 1 0.47 0.72 0.03
90 INT241787 Negative_regulation of AQP2 1 0.57 1.38 0.03
91 INT280794 Localization of Aqp2 2 0.36 0.07 0
92 INT262504 Positive_regulation of Aqp1 1 0.25 0.43 0
93 INT157833 Negative_regulation of Negative_regulation of Aqp2 1 0.36 0 0
94 INT286264 Positive_regulation of Negative_regulation of AQP1 1 0.01 0.79 0
95 INT280786 Phosphorylation of Aqp2 1 0.32 0.24 0
96 INT262513 Negative_regulation of Binding of Aqp1 1 0.23 0.64 0
97 INT297668 Positive_regulation of Aqp2 1 0.45 0 0
98 INT108349 Regulation of AQP2 1 0.44 0 0
99 INT100325 Positive_regulation of AQP2 1 0.69 0 0
100 INT341042 Positive_regulation of Protein_catabolism of Aqp2 1 0.34 0.07 0
101 INT262514 Binding of Aqp1 1 0.20 0.64 0
102 INT191283 Transcription of ABP1 1 0.53 0.44 0
103 INT100326 Positive_regulation of Localization of AQP2 1 0.69 0 0
104 INT57804 Localization of Txnrd1 1 0.61 0.07 0
105 INT341039 Protein_catabolism of Aqp2 1 0.47 0.06 0
106 INT299193 Transcription of Aqp1 1 0.56 0.62 0
107 INT262511 Positive_regulation of Gene_expression of Aqp1 1 0.37 1.78 0
108 INT188052 Positive_regulation of Txnrd1 1 0.23 0.25 0
109 INT191282 Regulation of Gene_expression of ABP1 1 0.35 0.46 0
110 INT327782 Regulation of Gene_expression of AQP1 1 0.36 1.63 0
111 INT100327 Regulation of Positive_regulation of AQP2 1 0.39 0 0
112 INT343971 Positive_regulation of Positive_regulation of SNCA 1 0.42 0.35 0
113 INT262512 Localization of Aqp1 1 0.40 0.7 0
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