GO:0071300

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Name cellular response to retinoic acid
Categary Process
Go Slim No
Go Link GO:0071300
Unique Molecular Interactions 412
Total Molecular Interactions 531
Total Single Events 4486
Pain Genes Associated 43

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cellular response to retinoic acid. They are ordered first by their pain relevance and then by number of times they were reported for cellular response to retinoic acid. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT44716 Binding of ABL2 and PDYN 2 0.40 0.66 4.77
2 INT7193 Abl2 Positive_regulation of Ctsb 1 0.21 0 3.21
3 INT83169 Binding of Cck and Lep 7 0.42 1.58 2.78
4 INT278948 LEP Positive_regulation of Gene_expression of PTGER2 1 0.09 4.04 2.69
5 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
6 INT83170 Lep Regulation of Cck 5 0.43 0.68 1.96
7 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
8 INT157460 CX3CL1 Regulation of Gene_expression of COL1A1 1 0.11 1.57 1.37
9 INT342165 Binding of Aqp1 and Nav1 1 0.25 0.57 1.25
10 INT180814 Binding of Ret and Gdnf 1 0.01 1.31 1.17
11 INT7191 Negative_regulation of Abl2 Positive_regulation of Ctsb 1 0.13 0 1.04
12 INT277192 SUGT1 Positive_regulation of Gene_expression of SLC6A4 1 0.01 0.86 1.04
13 INT144108 Binding of SLC6A3 and SLC6A4 1 0.12 0.64 1.03
14 INT117311 HP Positive_regulation of Lep 1 0.00 1.78 1.01
15 INT278962 LEP Positive_regulation of CPOX 1 0.05 1.33 1
16 INT278940 LEP Positive_regulation of Gene_expression of IL8 1 0.34 1.68 0.96
17 INT222979 Negative_regulation of Binding of COL1A1 and FN1 1 0.01 1.64 0.93
18 INT222978 Binding of COL1A1 and FN1 1 0.01 1.64 0.92
19 INT147507 Binding of Ret and Gtf3a 1 0.03 0.81 0.92
20 INT147505 Binding of Ret and Gdnf 1 0.27 0.81 0.92
21 INT149386 Binding of Lyn and TRPV4 1 0.40 1.14 0.91
22 INT222988 TNF Positive_regulation of Protein_catabolism of COL1A1 1 0.01 1.66 0.9
23 INT135781 Cyp3a23/3a1 Positive_regulation of Positive_regulation of Col1a1 1 0.01 0.78 0.8
24 INT130948 Amt Regulation of Gene_expression of LEP 1 0.00 1.04 0.78
25 INT130949 Amt Regulation of LEP 1 0.00 1.04 0.77
26 INT278958 LEP Positive_regulation of IL1B 1 0.33 1.91 0.74
27 INT132166 PSG7 Positive_regulation of Muc5ac 1 0.00 0 0.73
28 INT284481 Binding of ABCA1 and Ighg1 1 0.00 1.39 0.7
29 INT89009 Lep Positive_regulation of Cck 2 0.67 0.43 0.69
30 INT278956 LEP Regulation of Gene_expression of IL8 1 0.30 1.11 0.69
31 INT278968 LEP Regulation of Gene_expression of IL6 1 0.29 1.11 0.69
32 INT278951 LEP Regulation of Gene_expression of PTGER2 1 0.07 1.11 0.69
33 INT129919 IFNA2 Positive_regulation of Gene_expression of SLC6A4 1 0.02 0.38 0.69
34 INT129921 IL4 Positive_regulation of Gene_expression of SLC6A4 1 0.01 0.38 0.68
35 INT278965 LEP Positive_regulation of Gene_expression of NOS2 2 0.29 2.12 0.66
36 INT338390 Thim Regulation of Gene_expression of Ret 1 0.02 0.43 0.65
37 INT114845 RET Regulation of Gene_expression of Lgals1 1 0.02 0.84 0.65
38 INT352462 Gse1 Positive_regulation of Gene_expression of Tnc 1 0.05 0.75 0.64
39 INT144107 Binding of SLC6A2 and SLC6A4 1 0.00 0.18 0.62
40 INT352459 Gse1 Regulation of Gene_expression of Tnc 1 0.05 0 0.6
41 INT280895 Runx1 Positive_regulation of Gene_expression of Ret 2 0.33 0.2 0.58
42 INT98034 Binding of Ret and Trpv1 1 0.43 0.42 0.58
43 INT349083 Binding of Lep and Rtn1 1 0.09 1.68 0.57
44 INT202157 Binding of CSF1R and SLC6A4 1 0.08 0.9 0.54
45 INT204087 IL1B Positive_regulation of Gene_expression of LEP 1 0.09 2.6 0.54
46 INT125699 CR1 Negative_regulation of Positive_regulation of ABCA1 1 0.03 0.64 0.53
47 INT128431 SLC6A4 Regulation of S100A4 1 0.48 0.65 0.53
48 INT242613 Binding of Gfra2 and Ret 1 0.02 0 0.52
49 INT345308 Binding of ABCA1 and TIMP2 1 0.00 0.21 0.52
50 INT47745 Binding of Slc6a4 and Htr2a 1 0.33 0.09 0.52
51 INT187114 TIMP2 Negative_regulation of ABCA1 1 0.02 0.28 0.51
52 INT120852 PRL Positive_regulation of IRF1 1 0.44 0.99 0.51
53 INT271191 Bdnf Regulation of Slc6a4 1 0.03 0.29 0.51
54 INT187108 TIMP1 Negative_regulation of ABCA1 1 0.02 0.28 0.51
55 INT120854 IRF1 Positive_regulation of Localization of TNF 1 0.20 0.94 0.49
56 INT162890 Negative_regulation of Binding of LEP and Tnf 1 0.03 0.49 0.48
57 INT162889 Binding of LEP and Tnf 1 0.03 0.49 0.48
58 INT193480 Binding of ABCA1 and IRF6 1 0.00 1.08 0.46
59 INT242628 Binding of Gfra1 and Ret 1 0.03 0 0.46
60 INT242615 Ret Positive_regulation of Gene_expression of Gfra1 1 0.04 0 0.46
61 INT242596 Binding of Ntrk1 and Ret 1 0.12 0 0.46
62 INT132509 Binding of LEP and Cck 1 0.13 0.16 0.45
63 INT113248 Olr1259 Negative_regulation of Slc6a4 1 0.00 0.23 0.44
64 INT309157 Aqp1 Positive_regulation of Bdnf 1 0.00 0.74 0.42
65 INT323880 Binding of BMI1 and LEP 1 0.02 3.97 0.41
66 INT83171 Cck Regulation of Lep 1 0.30 0.09 0.4
67 INT97395 Lep Positive_regulation of Stat3 1 0.67 0.42 0.4
68 INT242607 Negative_regulation of Ntrk1 Positive_regulation of Ret 1 0.16 0 0.39
69 INT132171 PSG7 Positive_regulation of Localization of Muc5ac 1 0.00 0 0.39
70 INT143747 Binding of IL6 and LEP 2 0.04 4.05 0.38
71 INT273617 Gene_expression of Slc6a4 Positive_regulation of Pah 1 0.02 0.93 0.38
72 INT300488 Binding of CRP and LEP 1 0.46 2.03 0.37
73 INT154782 Binding of SLC6A4 and Ndst2 1 0.01 0 0.37
74 INT226785 Angpt2 Positive_regulation of Localization of Lep 1 0.01 1.65 0.36
75 INT278966 MAPK14 Positive_regulation of Gene_expression of LEP 1 0.16 0.62 0.36
76 INT278949 JAK3 Positive_regulation of Gene_expression of LEP 1 0.42 0.63 0.36
77 INT223470 Ret Regulation of Ntrk1 1 0.21 0 0.36
78 INT148240 Binding of Kit and Ret 1 0.24 0.44 0.35
79 INT323885 LEP Regulation of Gene_expression of NOS2 1 0.26 1.07 0.35
80 INT132174 PSG7 Positive_regulation of Gene_expression of Muc1 1 0.00 0 0.34
81 INT132172 PSG7 Positive_regulation of Gene_expression of Muc5ac 1 0.00 0 0.34
82 INT140667 IFNG Regulation of Gene_expression of SLC6A4 1 0.40 0.41 0.34
83 INT132169 PSG7 Positive_regulation of Muc1 1 0.00 0 0.34
84 INT140666 TNF Regulation of Gene_expression of SLC6A4 1 0.40 0.41 0.34
85 INT149896 Ihh Regulation of Gene_expression of Col1a1 1 0.06 0.89 0.33
86 INT44983 Ltc4s Positive_regulation of Rara 1 0.01 0.15 0.33
87 INT323870 LEP Regulation of Gene_expression of MMP13 1 0.21 1.76 0.33
88 INT44985 KNG1 Positive_regulation of Rara 1 0.00 0.15 0.32
89 INT161435 OPA1 Positive_regulation of Gene_expression of Tnc 1 0.02 0.21 0.32
90 INT105873 Ins1 Negative_regulation of Positive_regulation of Lep 1 0.27 0.67 0.31
91 INT278942 LEP Regulation of IL6 1 0.29 0.61 0.31
92 INT278939 LEP Regulation of IL8 1 0.13 0.61 0.31
93 INT278969 LEP Regulation of PTGER2 1 0.03 0.6 0.31
94 INT105874 Lep Negative_regulation of Positive_regulation of Ins1 1 0.27 0.67 0.31
95 INT226989 Lias Regulation of Gene_expression of Lep 1 0.10 0.91 0.3
96 INT278961 IL6 Regulation of Gene_expression of LEP 1 0.29 0.89 0.3
97 INT341777 SLC6A4 Regulation of EPHB1 1 0.02 0.96 0.3
98 INT139778 Binding of AQP1 and GBE1 1 0.00 0.22 0.3
99 INT245563 Negative_regulation of Runx1 Regulation of Ret 1 0.39 0.76 0.29
100 INT245556 Runx1 Regulation of Ret 1 0.56 0.76 0.29
101 INT211997 CORD1 Positive_regulation of Rara 1 0.01 0.68 0.29
102 INT137033 Tgfb1 Positive_regulation of Gene_expression of Col1a1 1 0.01 0.42 0.28
103 INT109098 Binding of ABL2 and PON1 1 0.36 1.32 0.28
104 INT225101 TGFB1 Positive_regulation of Localization of COL1A1 1 0.03 0.59 0.28
105 INT352452 Calca Regulation of Gene_expression of Tnc 1 0.04 0 0.28
106 INT137014 Positive_regulation of Pscs Positive_regulation of Gene_expression of Col1a1 1 0.01 0.42 0.28
107 INT225100 TGFB1 Positive_regulation of Gene_expression of COL1A1 1 0.04 0.59 0.28
108 INT352448 Gse1 Regulation of Tnc 1 0.03 0 0.28
109 INT352458 Dusp1 Regulation of Gene_expression of Tnc 1 0.07 0 0.28
110 INT137012 Pscs Positive_regulation of Gene_expression of Col1a1 1 0.01 0.42 0.28
111 INT100531 Cck Positive_regulation of Lep 1 0.70 0.15 0.26
112 INT228611 Binding of DNMT3B and LEP 1 0.04 0 0.25
113 INT271446 Thy1 Regulation of Col1a1 1 0.05 0.61 0.25
114 INT218732 Lep Regulation of Gene_expression of Trh 1 0.19 0.18 0.25
115 INT120853 PRL Positive_regulation of Positive_regulation of IRF1 1 0.41 0.49 0.25
116 INT125748 Binding of LEP and Gh 1 0.00 0.52 0.24
117 INT239337 Abca1 Positive_regulation of RCT 1 0.07 3.11 0.24
118 INT252784 ROS1 Positive_regulation of Gene_expression of COL1A1 1 0.05 1.86 0.24
119 INT147590 Binding of Muc1 and Mag 1 0.26 3.29 0.23
120 INT306795 Binding of LEP and SFTPD 1 0.08 1.13 0.23
121 INT108842 RARA Positive_regulation of Gene_expression of GDF15 1 0.52 0.68 0.23
122 INT323883 BMI1 Regulation of LEP 1 0.02 2.39 0.23
123 INT58305 AQP1 Regulation of Localization of TNF 1 0.10 0.16 0.22
124 INT58303 AQP1 Regulation of Gene_expression of IL1B 1 0.10 0.16 0.22
125 INT110653 Lep Regulation of Localization of Cck 1 0.06 0.22 0.22
126 INT311613 Binding of Slc6a4 and Pten 1 0.24 0.32 0.21
127 INT269180 LEP Positive_regulation of Localization of TNF 1 0.01 0.99 0.21
128 INT323873 LEP Regulation of Gene_expression of TIMP2 1 0.31 0.63 0.21
129 INT222482 Lep Positive_regulation of Localization of Gh1 1 0.02 1.02 0.2
130 INT225099 ZNF630 Positive_regulation of Gene_expression of COL1A1 1 0.00 0.17 0.2
131 INT342163 Nkx2-1 Regulation of Gene_expression of Aqp1 1 0.06 0.51 0.2
132 INT269446 Binding of EPHA3 and HHIP 1 0.01 0 0.2
133 INT217661 LEP Positive_regulation of INS 2 0.25 1.85 0.19
134 INT327814 Rab8a Regulation of Regulation of Lep 1 0.01 0.15 0.19
135 INT327813 Rab8a Regulation of Lep 1 0.01 0.15 0.19
136 INT319311 Binding of Glud1 and Ptk2b 1 0.36 0 0.19
137 INT242632 Ret Positive_regulation of Gene_expression of Trpa1 1 0.33 0.09 0.18
138 INT239316 Nr1h2 Positive_regulation of Transcription of Abca1 1 0.15 0.67 0.18
139 INT335046 PPARA Positive_regulation of Gene_expression of ABCA1 1 0.33 0.25 0.18
140 INT304964 Binding of AMT and PTK2B 1 0.23 0.78 0.18
141 INT306425 Positive_regulation of Binding of TBX1 and VCF 1 0.02 1.15 0.18
142 INT306426 Binding of TBX1 and VCF 1 0.01 1.09 0.17
143 INT207345 PTGDS Negative_regulation of Gene_expression of ABCA1 1 0.21 0 0.17
144 INT226988 Lias Positive_regulation of Localization of Lep 1 0.08 0.3 0.17
145 INT207359 ZNF398 Negative_regulation of ABCA1 1 0.01 0 0.17
146 INT208360 Binding of Abca1 and Apoe 1 0.15 0.74 0.17
147 INT343863 Binding of IRF1 and IRF3 1 0.03 0.12 0.17
148 INT313023 Binding of Rara and Rxra 1 0.06 0.73 0.17
149 INT207344 PTGER2 Negative_regulation of Gene_expression of ABCA1 1 0.04 0 0.17
150 INT207350 TBXA2R Regulation of Gene_expression of ABCA1 1 0.10 0 0.17
151 INT207338 Negative_regulation of CPOX Negative_regulation of ABCA1 1 0.11 0 0.16
152 INT241177 Abl2 Regulation of Cat 1 0.14 0.3 0.15
153 INT335459 ABCA1 Positive_regulation of ITPR3 1 0.00 0 0.15
154 INT85333 Aqp1 Positive_regulation of Negative_regulation of Tgfb1 1 0.25 0.67 0.15
155 INT327829 Aqp1 Regulation of Binding of Csf2 1 0.11 1 0.14
156 INT217667 LEP Negative_regulation of Localization of INS 1 0.15 1.18 0.14
157 INT319314 Binding of Ptk2b and Rbm39 1 0.01 0.08 0.14
158 INT156531 Binding of ABCA1 and HSD11B1 1 0.22 1.06 0.14
159 INT207360 PTGDS Negative_regulation of Negative_regulation of ABCA1 1 0.25 0 0.14
160 INT207337 PTGER2 Negative_regulation of Negative_regulation of ABCA1 1 0.04 0 0.14
161 INT319316 Binding of GRIN1 and Ptk2b 1 0.52 0.08 0.14
162 INT217664 LEP Negative_regulation of INS 1 0.15 1.18 0.14
163 INT207353 ZNF398 Regulation of ABCA1 1 0.00 0 0.14
164 INT82802 Binding of ABL2 and POMC 1 0.00 0 0.14
165 INT323877 LEP Positive_regulation of SOAT1 1 0.20 1.26 0.14
166 INT192106 Regulation of Binding of Rara and Retsat 1 0.00 0.83 0.13
167 INT139975 Binding of LEP and Prl 1 0.02 0.49 0.13
168 INT352450 Tnc Regulation of Trib3 1 0.00 0.22 0.13
169 INT328060 LEP Positive_regulation of FAAH 1 0.06 0.7 0.13
170 INT346714 LEP Regulation of GALP 1 0.06 0.08 0.13
171 INT287884 WNT5A Positive_regulation of THEMIS 1 0.00 0.08 0.13
172 INT192105 Binding of Rara and Retsat 1 0.00 0.83 0.13
173 INT157602 Binding of COL1A1 and COL3A1 1 0.04 0 0.13
174 INT344706 Nr1h2 Regulation of Abca1 1 0.03 2.39 0.12
175 INT81179 LEP Regulation of Localization of GH1 1 0.11 0.91 0.12
176 INT129091 Binding of PIK3CG and Lyn 1 0.00 0.47 0.12
177 INT129075 Binding of Pik3r1 and Lyn 1 0.00 0.47 0.12
178 INT150532 LEP Negative_regulation of Adipoq 1 0.00 1.34 0.12
179 INT129093 Binding of Lyn and TCHP 1 0.00 0.49 0.12
180 INT129092 Binding of GRP and Lyn 1 0.00 0.48 0.12
181 INT150533 Positive_regulation of LEP Negative_regulation of Adipoq 1 0.00 1.34 0.12
182 INT164746 Binding of LEP and Adipoq 1 0.07 0.69 0.12
183 INT323871 LEP Regulation of Gene_expression of IGF1 1 0.14 1.19 0.11
184 INT96518 Regulation of Gdnf Positive_regulation of Ret 1 0.00 0.23 0.11
185 INT270746 INS Regulation of LEP 1 0.07 0.72 0.11
186 INT294742 Lep Positive_regulation of Localization of Icam1 1 0.15 0.48 0.11
187 INT293236 IDO1 Regulation of ABCA1 1 0.00 0 0.11
188 INT163817 Lep Positive_regulation of Phosphorylation of Akt1 1 0.33 0.31 0.11
189 INT258527 Binding of BRAF and RET 1 0.21 1.49 0.11
190 INT222472 Lep Positive_regulation of Localization of Cartpt 1 0.05 0 0.11
191 INT294445 KLK4 Negative_regulation of COL1A1 1 0.01 0 0.1
192 INT206056 PTK2B Negative_regulation of Positive_regulation of IRF6 1 0.00 0.66 0.1
193 INT192104 Binding of Rara and Rxrg 1 0.00 0.82 0.1
194 INT96519 Gdnf Positive_regulation of Ret 1 0.00 0.22 0.1
195 INT323879 LEP Regulation of SOAT1 1 0.15 1.15 0.1
196 INT179869 COL1A1 Positive_regulation of SOCS3 1 0.04 0.99 0.1
197 INT242627 Ngf Positive_regulation of Gene_expression of Ret 1 0.32 0.1 0.1
198 INT204086 TNF Positive_regulation of Gene_expression of LEP 1 0.48 0.74 0.1
199 INT258522 Binding of DDR1 and RET 1 0.03 1.05 0.1
200 INT123864 Lep Positive_regulation of Positive_regulation of Cck 1 0.45 0.1 0.09

Single Events

The table below shows the top 100 pain related interactions that have been reported for cellular response to retinoic acid. They are ordered first by their pain relevance and then by number of times they were reported in cellular response to retinoic acid. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT15091 Gene_expression of SLC6A4 101 0.78 29.91 53.64
2 INT17881 Gene_expression of LEP 278 0.78 221.61 48.31
3 INT104567 Gene_expression of Aqp1 47 0.78 44.84 28.68
4 INT15089 Regulation of SLC6A4 48 0.62 17.87 25.6
5 INT79979 Gene_expression of Ret 94 0.75 19.21 25.51
6 INT76743 Gene_expression of Slc6a4 55 0.76 13.53 24.9
7 INT76123 Gene_expression of Lep 193 0.78 94.17 22.76
8 INT82434 Positive_regulation of LEP 117 0.70 95.45 20.22
9 INT97984 Negative_regulation of SLC6A4 45 0.59 15.43 18.09
10 INT9750 Positive_regulation of Rara 39 0.66 12.44 15.83
11 INT62681 Negative_regulation of LEP 93 0.59 66.97 15.77
12 INT57734 Binding of SLC6A4 36 0.48 11.94 15.42
13 INT75908 Regulation of LEP 77 0.60 60.16 15.19
14 INT19963 Gene_expression of COL1A1 118 0.59 42.11 15.15
15 INT73641 Regulation of Lep 45 0.62 26.2 12.59
16 INT47743 Negative_regulation of Slc6a4 22 0.59 6.23 12.23
17 INT32054 Gene_expression of Tnc 14 0.59 9.36 12.22
18 INT126743 Positive_regulation of Gene_expression of LEP 61 0.66 50.02 11.17
19 INT82079 Positive_regulation of Lep 79 0.70 40 11.07
20 INT36453 Binding of ABCA1 48 0.45 19.9 10.84
21 INT66303 Regulation of Slc6a4 10 0.45 4.82 10.55
22 INT47744 Binding of Slc6a4 21 0.48 5.52 9.45
23 INT82078 Negative_regulation of Lep 54 0.59 20.47 9.38
24 INT28312 Gene_expression of ABCA1 85 0.72 37.69 9.27
25 INT64849 Gene_expression of Ret 24 0.75 14.36 9.1
26 INT67116 Gene_expression of Ntrk3 20 0.59 7.64 8.94
27 INT82082 Localization of Lep 63 0.81 26.41 8.56
28 INT75907 Binding of LEP 53 0.46 46.65 8.44
29 INT11652 Gene_expression of Rara 30 0.58 24.96 6.98
30 INT612 Positive_regulation of Orm1 15 0.68 5.24 6.73
31 INT15092 Positive_regulation of SLC6A4 17 0.67 7.32 6.7
32 INT60161 Gene_expression of EPHA3 43 0.75 3.66 6.25
33 INT109714 Transcription of SLC6A4 7 0.72 3.8 6.19
34 INT19086 Negative_regulation of COL1A1 32 0.38 16.77 5.98
35 INT146594 Negative_regulation of Gene_expression of LEP 25 0.42 18.88 5.71
36 INT4938 Localization of Tnc 5 0.65 1.73 5.64
37 INT65356 Localization of LEP 46 0.79 41.17 5.43
38 INT156134 Regulation of Gene_expression of Aqp1 5 0.59 7.2 5.3
39 INT137593 Regulation of Gene_expression of SLC6A4 7 0.60 2.59 5.23
40 INT85328 Negative_regulation of Aqp1 5 0.54 6.02 4.94
41 INT69215 Gene_expression of Col1a1 38 0.68 17.39 4.77
42 INT2848 Localization of ABCA1 23 0.70 10.64 4.73
43 INT79194 Positive_regulation of Tnc 5 0.41 2.25 4.69
44 INT79902 Gene_expression of AQP1 33 0.78 24.72 4.55
45 INT97391 Binding of Lep 18 0.48 8.97 4.47
46 INT19965 Positive_regulation of COL1A1 23 0.45 14.49 4.38
47 INT10374 Gene_expression of RARA 39 0.75 22.59 4.28
48 INT90890 Positive_regulation of RARA 25 0.67 9.32 4.2
49 INT32053 Positive_regulation of Gene_expression of Tnc 5 0.45 3.4 4.13
50 INT79343 Positive_regulation of Slc6a4 10 0.50 1.77 4.05
51 INT118583 Positive_regulation of IRF1 10 0.68 3.75 3.91
52 INT140670 Negative_regulation of Gene_expression of SLC6A4 4 0.51 2.7 3.88
53 INT119606 Regulation of Gene_expression of LEP 17 0.45 17.96 3.75
54 INT146946 Gene_expression of Lyn 16 0.76 8.9 3.75
55 INT85326 Positive_regulation of Aqp1 7 0.65 5.9 3.71
56 INT242569 Positive_regulation of Ret 17 0.55 3.61 3.54
57 INT104570 Localization of Aqp1 8 0.77 5.83 3.51
58 INT82077 Positive_regulation of Gene_expression of Lep 32 0.70 17.9 3.5
59 INT18670 Negative_regulation of ABCA1 16 0.54 5.8 3.39
60 INT81229 Binding of COL1A1 24 0.35 12.07 3.3
61 INT99291 Transcription of Slc6a4 7 0.46 1.16 3.28
62 INT28130 Positive_regulation of ABCA1 18 0.61 7.08 3.22
63 INT127455 Positive_regulation of Gene_expression of Slc6a4 9 0.59 5.62 3.2
64 INT100190 Regulation of Gene_expression of Slc6a4 5 0.39 1.8 3.14
65 INT67719 Positive_regulation of Col1a1 21 0.44 8.87 3.12
66 INT97443 Positive_regulation of Positive_regulation of LEP 13 0.50 11.91 2.65
67 INT80320 Negative_regulation of Gene_expression of Slc6a4 4 0.42 0.85 2.6
68 INT68091 Localization of COL1A1 19 0.66 9.13 2.56
69 INT269377 Positive_regulation of EPHA3 22 0.18 0.97 2.55
70 INT38631 Positive_regulation of Ret 8 0.39 3.23 2.52
71 INT8890 Transcription of Col1a1 10 0.63 4.02 2.48
72 INT4939 Negative_regulation of Tnc 2 0.32 0.79 2.46
73 INT79261 Positive_regulation of Gene_expression of COL1A1 24 0.36 7.49 2.45
74 INT190081 Gene_expression of Abca1 21 0.65 18.18 2.45
75 INT63333 Gene_expression of RET 24 0.76 30.09 2.41
76 INT103487 Positive_regulation of Positive_regulation of Lep 9 0.67 4.08 2.38
77 INT242548 Regulation of Gene_expression of Ret 7 0.49 1.2 2.33
78 INT97152 Protein_catabolism of COL1A1 11 0.74 8.03 2.3
79 INT17617 Gene_expression of ABL2 8 0.75 2.73 2.25
80 INT146945 Positive_regulation of Lyn 6 0.49 2.81 2.25
81 INT50392 Regulation of Ret 6 0.54 3.51 2.22
82 INT242551 Negative_regulation of Gene_expression of Ret 5 0.41 1.01 2.21
83 INT152554 Regulation of Transcription of SLC6A4 3 0.62 1.52 2.18
84 INT2611 Negative_regulation of AQP1 17 0.39 10.04 2.15
85 INT141721 Binding of Aqp1 5 0.37 1.77 2.15
86 INT203308 Regulation of Aqp1 4 0.48 2.59 2.13
87 INT82081 Regulation of Gene_expression of Lep 11 0.53 7.78 2.12
88 INT58287 Gene_expression of Orm1 3 0.66 1.17 2.12
89 INT83392 Transcription of Lep 6 0.54 5.07 2.04
90 INT102896 Binding of Ret 8 0.35 1.55 2.03
91 INT113717 Negative_regulation of Gene_expression of COL1A1 21 0.41 6.14 2.01
92 INT118884 Gene_expression of IRF1 5 0.66 2.71 2
93 INT195430 Regulation of Positive_regulation of SLC6A4 1 0.42 1.01 1.98
94 INT120857 Localization of Col1a1 10 0.71 2.33 1.93
95 INT161432 Negative_regulation of Gene_expression of Tnc 2 0.38 1.44 1.93
96 INT118882 Positive_regulation of Gene_expression of IRF1 1 0.49 1.35 1.92
97 INT111575 Gene_expression of Muc5ac 15 0.78 7.97 1.84
98 INT44723 Positive_regulation of ABL2 7 0.49 2.23 1.82
99 INT96116 Transcription of COL1A1 10 0.44 4.57 1.81
100 INT141937 Negative_regulation of Regulation of SLC6A4 1 0.41 0.27 1.8
101 INT207370 Negative_regulation of Gene_expression of ABCA1 1 0.54 2.75 1.78
102 INT82083 Negative_regulation of Gene_expression of Lep 12 0.56 8.07 1.75
103 INT36581 Binding of Orm1 6 0.48 0.47 1.73
104 INT192092 Positive_regulation of Gene_expression of Rara 8 0.32 4.41 1.68
105 INT116022 Positive_regulation of Positive_regulation of RARA 3 0.11 0.94 1.68
106 INT147808 Positive_regulation of Gene_expression of SLC6A4 4 0.50 1.03 1.57
107 INT242572 Positive_regulation of Gene_expression of Ret 6 0.40 0.29 1.56
108 INT153201 Negative_regulation of Gene_expression of Col1a1 7 0.38 6.37 1.52
109 INT67457 Binding of Rara 12 0.24 8.28 1.45
110 INT211054 Positive_regulation of AQP1 3 0.33 4.53 1.41
111 INT187617 Binding of Rxrb 7 0.06 4.86 1.37
112 INT327824 Positive_regulation of Gene_expression of Aqp1 4 0.67 5.4 1.37
113 INT73553 Gene_expression of Aqp1 23 0.67 4.65 1.34
114 INT120860 Positive_regulation of Gene_expression of Col1a1 12 0.44 4.84 1.34
115 INT168312 Positive_regulation of Gene_expression of EPHA3 8 0.49 0.97 1.32
116 INT44746 Localization of Ret 3 0.48 1.23 1.28
117 INT78692 Regulation of PTK2B 2 0.47 0.29 1.28
118 INT81400 Binding of RARA 25 0.36 12.93 1.27
119 INT132577 Binding of RXRB 12 0.30 6.58 1.25
120 INT319293 Phosphorylation of Ptk2b 9 0.80 3.14 1.24
121 INT59473 Negative_regulation of Col1a1 4 0.25 1.33 1.24
122 INT223448 Localization of Ret 2 0.60 0.58 1.23
123 INT71845 Positive_regulation of Positive_regulation of Col1a1 1 0.34 0.15 1.23
124 INT134663 Gene_expression of SOX9 40 0.75 9.07 1.2
125 INT150074 Gene_expression of WNT5A 8 0.75 6.3 1.17
126 INT47839 Localization of Slc6a4 4 0.79 0.96 1.14
127 INT166720 Positive_regulation of Rxrb 2 0.36 0.84 1.13
128 INT147286 Negative_regulation of Regulation of Slc6a4 1 0.21 0 1.13
129 INT182985 Transcription of RARA 9 0.60 3.52 1.12
130 INT82084 Positive_regulation of Localization of Lep 11 0.70 4.65 1.11
131 INT616 Regulation of Orm1 4 0.38 1.72 1.08
132 INT109396 Negative_regulation of RET 12 0.42 14.92 1.06
133 INT239302 Positive_regulation of Gene_expression of Abca1 9 0.32 9.1 1.06
134 INT274898 Positive_regulation of Positive_regulation of Lyn 1 0.35 1.51 1.05
135 INT98174 Positive_regulation of Gene_expression of ABL2 1 0.49 1.1 1.05
136 INT21546 Regulation of ABCA1 16 0.40 4.21 1.04
137 INT128444 Phosphorylation of SLC6A4 2 0.61 0.49 1.02
138 INT290411 Gene_expression of Ptk2b 10 0.65 3.72 1.01
139 INT130262 Gene_expression of Abl2 2 0.58 1.06 1
140 INT166889 Positive_regulation of Gene_expression of AQP1 10 0.70 6.43 0.99
141 INT156614 Regulation of Gene_expression of COL1A1 6 0.33 2.51 0.99
142 INT208932 Regulation of Ret 6 0.49 1.49 0.97
143 INT69758 Negative_regulation of Positive_regulation of Rara 2 0.32 0.24 0.97
144 INT67117 Negative_regulation of Gene_expression of Ntrk3 1 0.30 0.24 0.96
145 INT146939 Negative_regulation of Lyn 3 0.53 2.97 0.95
146 INT46783 Negative_regulation of Abl2 2 0.15 0.2 0.95
147 INT236927 Positive_regulation of Ptk2b 9 0.67 3.41 0.94
148 INT2425 Negative_regulation of Ret 3 0.58 1.77 0.94
149 INT166715 Gene_expression of Sox9 16 0.65 6.39 0.92
150 INT183362 Regulation of AQP1 3 0.23 1.49 0.92
151 INT149383 Binding of Lyn 1 0.36 1.14 0.91
152 INT92002 Transcription of Ret 3 0.43 1.58 0.9
153 INT192090 Localization of Rara 6 0.46 4.15 0.89
154 INT152101 Regulation of Transcription of Slc6a4 1 0.14 0 0.89
155 INT48251 Regulation of Positive_regulation of Rara 2 0.33 0 0.88
156 INT83461 Binding of RET 8 0.47 9.7 0.87
157 INT277586 Negative_regulation of Mef2c 36 0.59 11.03 0.86
158 INT8888 Regulation of Col1a1 4 0.13 1.97 0.86
159 INT117308 Negative_regulation of Localization of Lep 3 0.59 2.16 0.86
160 INT120366 Negative_regulation of Rara 2 0.35 0.15 0.86
161 INT121906 Positive_regulation of Gene_expression of Orm1 1 0.46 0.08 0.84
162 INT190089 Binding of Abca1 5 0.36 2.21 0.83
163 INT48250 Regulation of Rara 3 0.29 2.47 0.83
164 INT48249 Positive_regulation of Positive_regulation of Rara 2 0.26 0 0.83
165 INT258932 Positive_regulation of TBX1 3 0.39 2.73 0.82
166 INT67115 Transcription of Ntrk3 1 0.37 0.19 0.81
167 INT145306 Gene_expression of Sox9 5 0.54 2.47 0.8
168 INT269642 Binding of EPHA3 4 0.10 0.22 0.8
169 INT212109 Localization of RARA 5 0.65 3.17 0.79
170 INT67118 Regulation of Gene_expression of Ntrk3 1 0.31 0.17 0.79
171 INT130263 Positive_regulation of Gene_expression of Abl2 1 0.45 0.61 0.78
172 INT82080 Regulation of Localization of Lep 2 0.45 1.36 0.76
173 INT82071 Regulation of Ntrk3 1 0.14 0.25 0.76
174 INT124873 Positive_regulation of Positive_regulation of Tnc 1 0.35 0.14 0.75
175 INT111568 Transcription of Muc5ac 1 0.53 0.5 0.75
176 INT156533 Transcription of LEP 9 0.69 4.35 0.74
177 INT147809 Localization of SLC6A4 5 0.71 1.69 0.74
178 INT9928 Negative_regulation of Orm1 3 0.25 1.21 0.73
179 INT79784 Positive_regulation of RET 15 0.57 17.43 0.71
180 INT114842 Localization of RET 3 0.71 5.98 0.71
181 INT66940 Regulation of RET 7 0.52 5.61 0.69
182 INT202361 Gene_expression of Mef2c 28 0.78 5.53 0.67
183 INT164627 Positive_regulation of Gene_expression of ABCA1 9 0.61 3.95 0.67
184 INT91398 Regulation of RARA 7 0.59 5.84 0.67
185 INT132164 Gene_expression of Muc1 4 0.71 4.15 0.67
186 INT89520 Regulation of COL1A1 8 0.32 3.21 0.66
187 INT46784 Binding of Abl2 1 0.09 0 0.66
188 INT111566 Regulation of Transcription of Muc5ac 1 0.27 0.43 0.65
189 INT220433 Gene_expression of RXRB 3 0.14 1.83 0.63
190 INT83391 Negative_regulation of Transcription of Lep 1 0.43 0.34 0.6
191 INT150075 Positive_regulation of Gene_expression of WNT5A 2 0.67 2.53 0.59
192 INT248682 Gene_expression of Rxrb 8 0.60 1.41 0.58
193 INT184222 Negative_regulation of SOX9 7 0.41 2.68 0.58
194 INT157103 Transcription of SOX9 6 0.59 1.2 0.58
195 INT11431 Gene_expression of LTK 2 0.75 0.16 0.58
196 INT234472 Positive_regulation of Transcription of RARA 2 0.44 0.13 0.58
197 INT306798 Protein_catabolism of LEP 1 0.65 2.45 0.58
198 INT241175 Positive_regulation of Abl2 4 0.19 0.34 0.56
199 INT277710 Regulation of Localization of ABCA1 1 0.04 1.73 0.56
200 INT117091 Positive_regulation of Lyn 1 0.49 0.41 0.56
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