GO:0071320

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Name cellular response to cAMP
Categary Process
Go Slim No
Go Link GO:0071320
Unique Molecular Interactions 236
Total Molecular Interactions 303
Total Single Events 3158
Pain Genes Associated 28

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cellular response to cAMP. They are ordered first by their pain relevance and then by number of times they were reported for cellular response to cAMP. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69032 IL18 Positive_regulation of IFNA1 12 0.23 7.87 3.83
2 INT69030 IL18 Positive_regulation of IL12A 3 0.31 5.57 2.72
3 INT3573 Tf Negative_regulation of Localization of Gh1 1 0.36 0 1.49
4 INT176368 IL18 Positive_regulation of Gene_expression of IFNA1 1 0.16 2.53 1.35
5 INT160585 IL18 Positive_regulation of Gene_expression of OPRM1 1 0.09 0.54 1.35
6 INT342165 Binding of Aqp1 and Nav1 1 0.25 0.57 1.25
7 INT229913 Positive_regulation of Ntsr1 Positive_regulation of Gene_expression of Egr1 1 0.12 1.33 1.11
8 INT203178 IL18 Positive_regulation of Gene_expression of Lts1 1 0.01 1.98 1.02
9 INT229914 Egr1 Positive_regulation of Phosphorylation of Mapk3 1 0.46 1.03 1.02
10 INT61860 Akr1d1 Regulation of Egr1 1 0.01 0 0.96
11 INT61861 Akr1d1 Regulation of Positive_regulation of Egr1 1 0.01 0 0.96
12 INT22726 Positive_regulation of Ahr Positive_regulation of Hrtrt1 1 0.22 0.18 0.95
13 INT22725 Ahr Positive_regulation of Hrtrt1 1 0.22 0.18 0.95
14 INT61859 Akr1d1 Positive_regulation of Egr1 1 0.01 0 0.92
15 INT61862 Slc3a1 Positive_regulation of Egr1 1 0.05 0 0.92
16 INT75920 Slc8a1 Negative_regulation of Cpox 1 0.03 0.85 0.89
17 INT142278 Slc8a1 Regulation of Tnf 1 0.14 0.07 0.89
18 INT122350 Ngf Regulation of Hsd3b1 1 0.34 0 0.87
19 INT226371 IL18 Positive_regulation of IL4 4 0.05 2.49 0.79
20 INT91655 SLC8A1 Negative_regulation of CASP1 1 0.02 0.43 0.75
21 INT123494 Binding of Egr1 and Ccr5 1 0.04 0.94 0.71
22 INT224580 Gene_expression of IL18 Positive_regulation of SERPINH1 1 0.00 1.34 0.7
23 INT772 Tf Positive_regulation of Positive_regulation of Oprl1 1 0.11 0 0.7
24 INT778 Tf Positive_regulation of Gh1 1 0.14 0 0.7
25 INT782 Tf Positive_regulation of Prl 1 0.43 0 0.7
26 INT92025 Egr1 Positive_regulation of Jun 1 0.15 0.61 0.67
27 INT92026 Egr1 Positive_regulation of Fos 1 0.50 0.61 0.67
28 INT76877 Binding of Slc3a1 and Slc8a1 1 0.02 0 0.64
29 INT240066 KCNIP3 Regulation of SLC8A3 1 0.39 0.73 0.59
30 INT208372 Il13 Positive_regulation of Ahr 1 0.21 1.22 0.59
31 INT176370 IL18BP Negative_regulation of IL18 1 0.15 0.76 0.56
32 INT261478 Positive_regulation of Ephb1 Regulation of Gene_expression of Egr1 1 0.10 0.23 0.55
33 INT147575 Binding of Ahr and Cyp1a1 2 0.15 0.15 0.54
34 INT226360 IL18 Positive_regulation of Gene_expression of IL4 1 0.05 2.66 0.54
35 INT226348 IL18 Positive_regulation of Gene_expression of IL13 1 0.03 2.66 0.54
36 INT55445 Positive_regulation of Ahr Regulation of Mme 1 0.23 0 0.53
37 INT147576 Positive_regulation of Ahr Positive_regulation of Gene_expression of Scrg1 1 0.00 0.17 0.52
38 INT222284 Negative_regulation of Casp1 Negative_regulation of Il18 1 0.01 0.79 0.46
39 INT354395 TNFSF12 Regulation of Gene_expression of IL18 1 0.47 0.79 0.45
40 INT172136 IL18 Positive_regulation of Gene_expression of IFN1@ 1 0.09 0.63 0.42
41 INT118519 Slc8a1 Negative_regulation of Positive_regulation of Nfkb1 1 0.16 0.59 0.42
42 INT309157 Aqp1 Positive_regulation of Bdnf 1 0.00 0.74 0.42
43 INT176361 Positive_regulation of LBR Positive_regulation of Gene_expression of IL18 1 0.10 0.84 0.39
44 INT91656 SLC8A1 Negative_regulation of Positive_regulation of CASP1 1 0.01 0.2 0.38
45 INT91652 Negative_regulation of SLC8A1 Negative_regulation of CASP1 1 0.02 0.21 0.37
46 INT123495 Negative_regulation of Binding of Egr1 and Ccr5 1 0.03 0.48 0.36
47 INT123493 Regulation of Binding of Egr1 and Ccr5 1 0.03 0.48 0.36
48 INT176373 IL18 Regulation of FASLG 1 0.41 0.4 0.35
49 INT90722 Nr4a1 Positive_regulation of Egr1 1 0.20 0.48 0.35
50 INT90723 Nr4a2 Positive_regulation of Egr1 1 0.22 0.49 0.35
51 INT90724 Egr3 Positive_regulation of Egr1 1 0.33 0.48 0.35
52 INT353689 Binding of Slc8a1 and Ca2 1 0.15 0.58 0.33
53 INT207184 Binding of Adipoq and Lep 1 0.25 2.45 0.33
54 INT300729 IL18 Positive_regulation of IL13 1 0.00 0 0.33
55 INT174265 IL18 Regulation of Gene_expression of F3 1 0.00 3.21 0.33
56 INT98013 Il18 Positive_regulation of Gene_expression of IFNG 1 0.66 0.44 0.32
57 INT176362 Binding of IL18 and IL18BP 1 0.12 0.49 0.32
58 INT126097 Ddc Positive_regulation of Egr1 1 0.08 0 0.32
59 INT219151 IL18 Positive_regulation of CASP1 1 0.01 1.05 0.3
60 INT139778 Binding of AQP1 and GBE1 1 0.00 0.22 0.3
61 INT74334 Penk Regulation of Transcription of Egr1 1 0.40 0.25 0.29
62 INT74336 Crh Regulation of Transcription of Egr1 1 0.49 0.24 0.28
63 INT176372 Positive_regulation of IL18 Positive_regulation of IFNA1 1 0.16 0.36 0.28
64 INT3577 Tf Negative_regulation of Positive_regulation of Gh1 1 0.49 0 0.27
65 INT176369 IL18 Regulation of TH1L 1 0.27 0.33 0.26
66 INT279959 Tnfrsf1b Negative_regulation of Ahr 1 0.10 0.98 0.24
67 INT130060 PPARG Positive_regulation of Positive_regulation of Egr1 1 0.22 0.46 0.24
68 INT113419 IL10 Negative_regulation of Gene_expression of IL18 1 0.31 0.86 0.24
69 INT179492 Binding of Ins1 and Adipoq 1 0.16 1.16 0.23
70 INT179186 Fcer2a Regulation of Positive_regulation of Ahr 1 0.05 1.23 0.23
71 INT58305 AQP1 Regulation of Localization of TNF 1 0.10 0.16 0.22
72 INT58303 AQP1 Regulation of Gene_expression of IL1B 1 0.10 0.16 0.22
73 INT353691 Slc8a1 Positive_regulation of Ca2 1 0.18 0.45 0.22
74 INT249760 Positive_regulation of Cnr1 Negative_regulation of Gene_expression of Adipoq 1 0.20 0.81 0.22
75 INT260397 Positive_regulation of Hmox1 Positive_regulation of Gene_expression of Adipoq 1 0.37 0.78 0.22
76 INT303606 Binding of IL18 and SOAT1 1 0.05 0.52 0.22
77 INT242996 Adipoq Negative_regulation of Transcription of Cd68 1 0.22 0.6 0.21
78 INT242994 Adipoq Negative_regulation of Spp1 1 0.19 0.59 0.21
79 INT259817 Ltp Positive_regulation of Egr1 1 0.03 0.28 0.2
80 INT332304 Binding of Il6 and Adipoq 1 0.03 0.4 0.2
81 INT91653 Negative_regulation of CASP1 Negative_regulation of IL18 1 0.39 0.15 0.2
82 INT342163 Nkx2-1 Regulation of Gene_expression of Aqp1 1 0.06 0.51 0.2
83 INT145886 Binding of CXCL1 and Adipoq 1 0.00 0.77 0.2
84 INT352518 Binding of FAT1 and Adipoq 1 0.01 2.79 0.2
85 INT260394 Positive_regulation of Hmox1 Positive_regulation of Adipoq 1 0.37 0.78 0.19
86 INT259812 Gtf3a Regulation of Egr1 1 0.01 0.58 0.19
87 INT299113 Binding of INPP5K and GOPC 1 0.18 2.69 0.19
88 INT353697 Binding of NA and Slc8a1 1 0.01 0.42 0.19
89 INT259814 Binding of Arc and Egr1 1 0.34 0.55 0.19
90 INT259813 Binding of Egr1 and Arc 1 0.32 0.55 0.19
91 INT149096 PITX2 Positive_regulation of Gene_expression of Egr1 1 0.01 1.23 0.19
92 INT188921 Binding of Pc and Ahr 1 0.12 0 0.19
93 INT252788 Binding of IL12A and IL18 1 0.01 1.33 0.19
94 INT188920 Pc Positive_regulation of Ahr 1 0.14 0 0.18
95 INT316748 IL18 Positive_regulation of Regulation of Hand2 1 0.14 1.11 0.18
96 INT207186 Binding of Adipoq and Bmi1 1 0.01 1.65 0.18
97 INT198382 Binding of AR and SRD5A1 2 0.06 0.84 0.17
98 INT228168 Adipoq Positive_regulation of Prkag1 2 0.05 1.08 0.17
99 INT159596 Binding of IL18 and IL18R1 1 0.08 0.17 0.17
100 INT354400 IL18 Regulation of Gene_expression of TNFSF12 1 0.35 0.55 0.17
101 INT134196 Ahr Regulation of Transcription of Cyp1a1 1 0.11 0.14 0.16
102 INT134202 Ahr Regulation of AHR 1 0.18 0.13 0.16
103 INT85333 Aqp1 Positive_regulation of Negative_regulation of Tgfb1 1 0.25 0.67 0.15
104 INT157275 Binding of PRKAA1 and Adipoq 1 0.01 1.13 0.15
105 INT327829 Aqp1 Regulation of Binding of Csf2 1 0.11 1 0.14
106 INT157273 Adipoq Positive_regulation of PRKAA1 1 0.03 1.16 0.14
107 INT247267 Binding of Egr1 and Mecp2 1 0.12 0.18 0.13
108 INT354403 IL18 Regulation of TNFSF12 1 0.35 0.11 0.13
109 INT338419 Il13 Regulation of Positive_regulation of Ahr 1 0.04 0.54 0.13
110 INT67619 Inpp5k Negative_regulation of Ptgs1 1 0.03 0.5 0.13
111 INT270663 Adipoq Positive_regulation of Il6 1 0.02 1.05 0.12
112 INT179493 Adipoq Positive_regulation of Ins1 1 0.20 0.99 0.12
113 INT270669 Adipoq Positive_regulation of IL8 1 0.01 1.06 0.12
114 INT150532 LEP Negative_regulation of Adipoq 1 0.00 1.34 0.12
115 INT150533 Positive_regulation of LEP Negative_regulation of Adipoq 1 0.00 1.34 0.12
116 INT270665 Adipoq Positive_regulation of Ccl2 1 0.07 1.06 0.12
117 INT164746 Binding of LEP and Adipoq 1 0.07 0.69 0.12
118 INT228175 RNU1-1 Regulation of Adipoq 1 0.11 0.78 0.12
119 INT312218 INPP5K Positive_regulation of Protein_catabolism of IGFBP3 1 0.17 0.39 0.11
120 INT336632 Ecm1 Regulation of Regulation of Ahr 1 0.03 0.61 0.11
121 INT257467 Fat1 Regulation of Gene_expression of Adipoq 1 0.08 0.56 0.11
122 INT312212 Binding of ADAM12 and INPP5K 1 0.16 0.46 0.11
123 INT325222 Il13 Regulation of Ahr 1 0.21 0.58 0.11
124 INT227061 Binding of Ahr and Alb 1 0.23 0.08 0.1
125 INT354401 TNFSF12 Regulation of IL18 1 0.47 0 0.1
126 INT204877 gr Negative_regulation of Serpina3n 1 0.23 0.15 0.1
127 INT294431 IL18 Positive_regulation of Gene_expression of SELE 1 0.06 0.98 0.1
128 INT310275 Negative_regulation of Binding of Adipoq and Ins1 1 0.19 1.14 0.09
129 INT294430 IL18 Positive_regulation of Gene_expression of VCAM1 1 0.10 0.91 0.09
130 INT157276 PPARG Positive_regulation of Adipoq 1 0.29 1.09 0.09
131 INT276814 IL18 Positive_regulation of Gene_expression of Hgs 1 0.05 0.09 0.09
132 INT157274 Adipoq Positive_regulation of ADIPOR1 1 0.00 1.2 0.09
133 INT354120 Binding of IGF2 and IGFBP5 1 0.01 0.45 0.09
134 INT241040 Slc8a1 Negative_regulation of Gene_expression of Ca2 1 0.15 1.35 0.09
135 INT310274 Binding of Adipoq and Ins1 1 0.21 1.14 0.09
136 INT165157 Gli1 Regulation of Igfbp5 1 0.24 0.07 0.09
137 INT239839 IL18 Positive_regulation of TNF 1 0.11 1.08 0.09
138 INT228174 RNU1-1 Positive_regulation of Gene_expression of Adipoq 1 0.12 0.55 0.08
139 INT257466 Psd Negative_regulation of Gene_expression of Adipoq 1 0.22 0.66 0.08
140 INT354402 IL18 Positive_regulation of Gene_expression of TNFSF12 1 0.39 0.55 0.08
141 INT312219 Binding of IGF1 and IGFBP5 1 0.02 0.13 0.08
142 INT352517 Binding of INS and Adipoq 1 0.09 1.32 0.07
143 INT267016 Bdnf Positive_regulation of Egr1 1 0.12 0.09 0.07
144 INT260392 Hmox1 Positive_regulation of Adipoq 1 0.32 0.65 0.07
145 INT336380 Gene_expression of Adipoq Positive_regulation of Ppara 1 0.06 1.77 0.07
146 INT354391 Binding of IL18 and UNK 1 0.23 0.66 0.06
147 INT140813 Binding of Retn and Adipoq 1 0.03 1.18 0.06
148 INT312228 INPP5K Regulation of TGFB1 1 0.06 0.08 0.05
149 INT354397 Positive_regulation of IL18 Regulation of Gene_expression of TNFSF12 1 0.18 0 0.05
150 INT181601 Binding of TP53 and WT1 1 0.30 0.9 0.05
151 INT312226 INPP5K Positive_regulation of IGFBP5 1 0.12 0.07 0.05
152 INT228169 Gm2733 Regulation of Adipoq 1 0.00 0.51 0.05
153 INT194735 IL18 Positive_regulation of Positive_regulation of MAPK1 1 0.05 0 0.04
154 INT285388 Ahr Positive_regulation of Gene_expression of Cyp27b1 1 0.01 0.14 0.04
155 INT60221 Agt Regulation of Gene_expression of Egr1 1 0.42 0 0.04
156 INT285386 Ahr Positive_regulation of Binding of Cyp27b1 1 0.01 0.14 0.04
157 INT194741 IL18 Positive_regulation of Gene_expression of GADD45A 1 0.05 0 0.04
158 INT228591 Adipoq Positive_regulation of Phosphorylation of Prkaa2 1 0.31 0.61 0.04
159 INT194704 IL18 Positive_regulation of GADD45A 1 0.08 0 0.04
160 INT247080 Binding of CRH and CRHBP 1 0.11 0.2 0.03
161 INT236590 Binding of Adipoq and Ncoa2 1 0.15 0.2 0.03
162 INT197296 Ahr Regulation of Bhlha15 1 0.48 0.47 0.03
163 INT236587 Binding of Adipoq and Ncoa1 1 0.17 0.2 0.03
164 INT297207 Myoz1 Regulation of Gene_expression of Slc8a1 1 0.09 0.26 0.03
165 INT314370 Adipoq Positive_regulation of Tnfrsf11a 1 0.04 1.26 0.03
166 INT247085 Binding of CRHBP and GHRH 1 0.01 0.2 0.03
167 INT236592 Positive_regulation of Binding of Adipoq and Ncoa2 1 0.19 0.2 0.03
168 INT312224 INPP5K Regulation of Negative_regulation of COL1A1 1 0.08 0 0
169 INT165187 Positive_regulation of Binding of CST3 and IL18 1 0.03 0.28 0
170 INT165197 Positive_regulation of Binding of IL18 and Havcr1 1 0.00 0.28 0
171 INT165195 Binding of IL18 and Havcr1 1 0.00 0.28 0
172 INT312221 Binding of TGFB1 and INPP5K 1 0.09 0 0
173 INT227305 Zbp1 Regulation of Gene_expression of Adipoq 1 0.21 1.27 0
174 INT259451 Binding of DHCR7 and Cyp11a1 1 0.01 0.3 0
175 INT312220 IL4 Positive_regulation of Regulation of INPP5K 1 0.05 0.24 0
176 INT252910 PTTG1 Negative_regulation of Transcription of SLC5A5 1 0.02 0.36 0
177 INT324306 Binding of GATM and STC1 1 0.02 1.61 0
178 INT312222 IFNA1 Positive_regulation of Regulation of INPP5K 1 0.05 0.24 0
179 INT165198 Positive_regulation of Binding of IL18 and Fabp1 1 0.01 0.55 0
180 INT340275 NFATC1 Positive_regulation of Binding of Ahr 1 0.10 0.51 0
181 INT252898 Binding of SLC5A5 and USF1 1 0.01 0.22 0
182 INT252906 Binding of SLC5A5 and PTTG1 1 0.01 0.69 0
183 INT352516 Binding of POMT1 and Adipoq 1 0.01 0.4 0
184 INT312230 INPP5K Regulation of Gene_expression of COL2A1 1 0.06 0 0
185 INT312225 Positive_regulation of INPP5K Positive_regulation of CD44 1 0.15 0.1 0
186 INT312214 INPP5K Regulation of Gene_expression of COL1A1 1 0.08 0 0
187 INT260395 Positive_regulation of Adipoq Negative_regulation of Gene_expression of Hmox1 1 0.34 1.4 0
188 INT165190 Binding of IL18 and LCN2 1 0.00 0.28 0
189 INT259811 Narp Positive_regulation of Gene_expression of Egr1 1 0.26 0.86 0
190 INT252888 Binding of SLC5A5 and PAX8 1 0.02 0.22 0
191 INT79900 NFE2L2 Positive_regulation of Gene_expression of AQP1 1 0.03 0 0
192 INT140814 Adipoq Regulation of Retn 1 0.03 0.8 0
193 INT252905 PTTG1IP Negative_regulation of Transcription of SLC5A5 1 0.01 0.35 0
194 INT189127 Mch Positive_regulation of Ahr 1 0.18 0.29 0
195 INT227302 Zbp1 Regulation of Transcription of Adipoq 1 0.09 1.27 0
196 INT324313 Binding of STC1 and UMOD 1 0.29 3.22 0
197 INT197304 Ahr Regulation of Hes1 1 0.06 0.17 0
198 INT139563 Tlr4 Positive_regulation of Localization of IL18 1 0.01 0 0
199 INT312223 INPP5K Negative_regulation of Gene_expression of COL10A1 1 0.04 0.1 0
200 INT312227 INPP5K Regulation of Negative_regulation of COL2A1 1 0.06 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cellular response to cAMP. They are ordered first by their pain relevance and then by number of times they were reported in cellular response to cAMP. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5861 Gene_expression of Egr1 203 0.78 49.35 68.13
2 INT5862 Positive_regulation of Egr1 82 0.70 30.4 33.96
3 INT104567 Gene_expression of Aqp1 47 0.78 44.84 28.68
4 INT69036 Gene_expression of IL18 99 0.77 77.92 25.95
5 INT6054 Positive_regulation of Gene_expression of Egr1 67 0.70 18.45 25.93
6 INT87861 Gene_expression of Il18 33 0.78 30.44 18.42
7 INT117500 Gene_expression of Adipoq 90 0.74 67.79 16.58
8 INT26975 Gene_expression of Adipoq 113 0.75 106.71 14.46
9 INT117502 Positive_regulation of Adipoq 70 0.63 40.43 12.03
10 INT75919 Gene_expression of Slc8a1 23 0.63 16.44 9.84
11 INT87863 Positive_regulation of IL18 40 0.69 34.08 9.53
12 INT99495 Gene_expression of SRD5A1 14 0.77 5 9.21
13 INT90603 Positive_regulation of Ahr 103 0.69 58.65 7.73
14 INT6055 Transcription of Egr1 47 0.69 3.61 7.68
15 INT14166 Positive_regulation of Ahr 32 0.61 20.78 7.47
16 INT94127 Positive_regulation of Il18 14 0.69 14 7.47
17 INT125136 Regulation of Adipoq 24 0.56 16.82 7.23
18 INT6057 Negative_regulation of Gene_expression of Egr1 17 0.57 4.17 7.17
19 INT47707 Negative_regulation of Egr1 9 0.41 0.17 7.03
20 INT91721 Binding of IL18 21 0.48 21.17 6.56
21 INT5860 Regulation of Gene_expression of Egr1 20 0.62 3.02 6.38
22 INT146043 Positive_regulation of Gene_expression of Adipoq 39 0.67 29.93 6.12
23 INT91657 Negative_regulation of IL18 20 0.48 15.97 6.12
24 INT113420 Positive_regulation of Gene_expression of IL18 22 0.69 19.96 5.53
25 INT156134 Regulation of Gene_expression of Aqp1 5 0.59 7.2 5.3
26 INT47704 Regulation of Egr1 17 0.60 2.43 5.18
27 INT47706 Negative_regulation of Positive_regulation of Egr1 9 0.41 6.11 5.1
28 INT117499 Negative_regulation of Adipoq 28 0.56 24.15 5.07
29 INT85328 Negative_regulation of Aqp1 5 0.54 6.02 4.94
30 INT51944 Positive_regulation of Transcription of Egr1 12 0.49 1.96 4.72
31 INT79902 Gene_expression of AQP1 33 0.78 24.72 4.55
32 INT11565 Gene_expression of Tf 24 0.68 5.89 4.36
33 INT14165 Negative_regulation of Ahr 14 0.51 8.35 4.17
34 INT35175 Localization of IL18 18 0.80 12.96 3.83
35 INT123502 Binding of Egr1 11 0.35 6.7 3.77
36 INT99889 Transcription of SRD5A1 5 0.71 1.45 3.74
37 INT85326 Positive_regulation of Aqp1 7 0.65 5.9 3.71
38 INT112340 Gene_expression of Cyp11a1 11 0.77 5.19 3.7
39 INT31580 Negative_regulation of Cyp11a1 14 0.57 3.48 3.61
40 INT28021 Positive_regulation of Adipoq 42 0.67 30.79 3.58
41 INT104570 Localization of Aqp1 8 0.77 5.83 3.51
42 INT148151 Regulation of Il18 7 0.28 5.4 3.5
43 INT147572 Gene_expression of Ahr 73 0.75 38.99 3.15
44 INT117501 Positive_regulation of Gene_expression of Adipoq 24 0.63 12.99 3.1
45 INT47207 Negative_regulation of Ahr 25 0.52 16.11 3.02
46 INT64386 Binding of Cyp11a1 13 0.46 5.09 3.01
47 INT16616 Negative_regulation of SRD5A1 44 0.57 34.81 2.96
48 INT176383 Negative_regulation of Binding of IL18 1 0.35 5.91 2.91
49 INT15157 Gene_expression of INPP5K 30 0.67 15.49 2.85
50 INT44661 Regulation of Ahr 15 0.45 12.69 2.79
51 INT139562 Transcription of IL18 10 0.68 6.14 2.73
52 INT67618 Positive_regulation of Inpp5k 3 0.45 0.77 2.64
53 INT26974 Negative_regulation of Adipoq 27 0.52 26.01 2.59
54 INT118518 Positive_regulation of Slc8a1 7 0.56 5.31 2.59
55 INT222289 Localization of Il18 4 0.30 3.24 2.58
56 INT133567 Regulation of IL18 11 0.50 9.54 2.31
57 INT122561 Negative_regulation of Gene_expression of Adipoq 12 0.56 14.02 2.26
58 INT135451 Positive_regulation of Positive_regulation of Adipoq 3 0.40 2.06 2.24
59 INT148152 Binding of Il18 4 0.46 4.44 2.19
60 INT2611 Negative_regulation of AQP1 17 0.39 10.04 2.15
61 INT141721 Binding of Aqp1 5 0.37 1.77 2.15
62 INT203308 Regulation of Aqp1 4 0.48 2.59 2.13
63 INT80599 Regulation of Positive_regulation of Egr1 3 0.28 0.46 2.09
64 INT94128 Positive_regulation of Gene_expression of Il18 6 0.50 3.64 2.06
65 INT118305 Negative_regulation of Gene_expression of IL18 7 0.39 6.52 2.05
66 INT138029 Binding of Adipoq 10 0.40 6.81 2.04
67 INT342815 Positive_regulation of Transcription of SRD5A1 1 0.49 0.33 2.04
68 INT134633 Localization of Adipoq 9 0.60 6.39 2.03
69 INT98888 Negative_regulation of Gene_expression of Il18 3 0.43 1.72 2.02
70 INT83329 Regulation of Gene_expression of Tf 4 0.16 1.83 1.93
71 INT160634 Gene_expression of Slc8a1 2 0.64 2.12 1.92
72 INT36499 Negative_regulation of Tf 6 0.38 3.02 1.85
73 INT25835 Binding of Slc8a1 3 0.36 0.47 1.79
74 INT122346 Gene_expression of Hsd3b1 1 0.75 0 1.78
75 INT227273 Localization of Adipoq 22 0.72 18.04 1.72
76 INT14167 Negative_regulation of Positive_regulation of Ahr 5 0.51 1.54 1.71
77 INT112339 Localization of Cyp11a1 2 0.71 0.94 1.68
78 INT73355 Negative_regulation of Slc8a1 5 0.47 2.35 1.61
79 INT141455 Negative_regulation of Inpp5k 2 0.36 1.09 1.51
80 INT90604 Positive_regulation of Positive_regulation of Ahr 8 0.45 3.52 1.45
81 INT53003 Positive_regulation of Positive_regulation of Egr1 6 0.64 2.36 1.44
82 INT54805 Regulation of Ahr 7 0.22 4.14 1.41
83 INT211054 Positive_regulation of AQP1 3 0.33 4.53 1.41
84 INT10570 Positive_regulation of Cyp11a1 9 0.47 2.67 1.4
85 INT327824 Positive_regulation of Gene_expression of Aqp1 4 0.67 5.4 1.37
86 INT73553 Gene_expression of Aqp1 23 0.67 4.65 1.34
87 INT122345 Positive_regulation of Gene_expression of Hsd3b1 1 0.49 0 1.34
88 INT159598 Positive_regulation of Transcription of IL18 3 0.48 1.84 1.32
89 INT125296 Regulation of Inpp5k 1 0.22 0 1.32
90 INT3816 Gene_expression of Ahr 13 0.65 7.51 1.31
91 INT69037 Regulation of Gene_expression of IL18 4 0.43 3.29 1.31
92 INT36500 Negative_regulation of Gene_expression of Tf 4 0.38 1.22 1.29
93 INT198387 Regulation of SRD5A1 2 0.60 1.29 1.26
94 INT29693 Binding of Ahr 11 0.31 13.27 1.23
95 INT769 Regulation of Tf 3 0.30 1 1.18
96 INT143846 Positive_regulation of INPP5K 5 0.40 6.4 1.17
97 INT176379 Regulation of Binding of IL18 1 0.37 2.37 1.17
98 INT227275 Negative_regulation of Gene_expression of Adipoq 19 0.53 19.51 1.15
99 INT35174 Positive_regulation of Localization of IL18 7 0.69 5.22 1.08
100 INT123503 Positive_regulation of Binding of Egr1 3 0.13 2.34 1.04
101 INT154493 Regulation of Gene_expression of SRD5A1 3 0.45 0.58 1.03
102 INT80500 Localization of Slc8a1 4 0.61 1.37 1.02
103 INT45079 Binding of Ahr 21 0.44 10.07 1
104 INT3568 Localization of Tf 4 0.62 1.27 1
105 INT166889 Positive_regulation of Gene_expression of AQP1 10 0.70 6.43 0.99
106 INT123501 Negative_regulation of Binding of Egr1 2 0.12 2.04 0.99
107 INT122347 Transcription of Hsd3b1 1 0.52 0 0.99
108 INT51947 Regulation of Transcription of Egr1 2 0.59 0.15 0.96
109 INT10578 Transcription of Cyp11a1 3 0.53 0.84 0.93
110 INT183362 Regulation of AQP1 3 0.23 1.49 0.92
111 INT160140 Regulation of Binding of Adipoq 1 0.37 0.87 0.92
112 INT227270 Regulation of Gene_expression of Adipoq 5 0.55 7.35 0.85
113 INT89368 Positive_regulation of Tf 7 0.34 3.62 0.83
114 INT91666 Localization of SLC8A1 2 0.02 0.25 0.82
115 INT151927 Regulation of Gene_expression of Adipoq 3 0.43 3.32 0.81
116 INT142013 Positive_regulation of Regulation of Adipoq 1 0.03 0.65 0.78
117 INT28020 Binding of Adipoq 10 0.36 11.49 0.77
118 INT163786 Regulation of Gene_expression of Il18 1 0.28 0.88 0.74
119 INT163788 Negative_regulation of Regulation of Il18 1 0.27 0.87 0.73
120 INT6050 Localization of Egr1 4 0.68 0.53 0.7
121 INT138489 Negative_regulation of Il18 1 0.02 0.48 0.7
122 INT148756 Regulation of Adipoq 10 0.60 7.83 0.67
123 INT208367 Regulation of Localization of Ahr 1 0.30 1.6 0.67
124 INT208371 Localization of Ahr 2 0.50 1.9 0.66
125 INT102686 Phosphorylation of Egr1 3 0.59 2.57 0.64
126 INT114942 Negative_regulation of Positive_regulation of Ahr 5 0.55 2.65 0.62
127 INT118310 Negative_regulation of Positive_regulation of Adipoq 2 0.34 2.47 0.61
128 INT179488 Positive_regulation of Transcription of Adipoq 3 0.37 0.5 0.6
129 INT131421 Localization of INPP5K 9 0.74 4.3 0.59
130 INT299115 Regulation of INPP5K 6 0.39 4.11 0.59
131 INT13724 Positive_regulation of WT1 5 0.69 4.99 0.59
132 INT88694 Gene_expression of WT1 17 0.75 21.88 0.56
133 INT139780 Binding of AQP1 7 0.32 4.62 0.54
134 INT147571 Regulation of Binding of Ahr 1 0.26 0.15 0.54
135 INT81061 Regulation of Negative_regulation of Egr1 1 0.22 0 0.53
136 INT176384 Positive_regulation of Binding of IL18 1 0.41 0.98 0.51
137 INT342811 Positive_regulation of Gene_expression of SRD5A1 1 0.45 0.22 0.5
138 INT227272 Transcription of Adipoq 8 0.64 8.29 0.49
139 INT241034 Negative_regulation of Gene_expression of Slc8a1 4 0.34 2.23 0.48
140 INT241035 Positive_regulation of Gene_expression of Slc8a1 4 0.41 1.89 0.47
141 INT122348 Regulation of Hsd3b1 1 0.60 0 0.46
142 INT68725 Regulation of Cyp11a1 6 0.19 2.62 0.44
143 INT19592 Localization of AQP1 4 0.81 1.09 0.44
144 INT327786 Negative_regulation of Gene_expression of AQP1 3 0.29 4.21 0.44
145 INT121113 Protein_catabolism of Cyp11a1 2 0.65 0.37 0.44
146 INT305077 Localization of CRHBP 1 0.76 0.28 0.44
147 INT94035 Transcription of Ahr 1 0.53 0.53 0.43
148 INT308980 Positive_regulation of Negative_regulation of Adipoq 3 0.33 2.3 0.4
149 INT91668 Positive_regulation of Negative_regulation of IL18 1 0.38 0.24 0.38
150 INT168788 Positive_regulation of Positive_regulation of Il18 1 0.16 0.73 0.38
151 INT241036 Regulation of Slc8a1 5 0.22 3.43 0.37
152 INT203374 Positive_regulation of Regulation of Aqp1 2 0.36 0.91 0.37
153 INT279958 Regulation of Regulation of Ahr 1 0.29 1.32 0.37
154 INT197286 Positive_regulation of Gene_expression of Ahr 10 0.67 9.78 0.36
155 INT12169 Gene_expression of Serpina3n 2 0.48 3.44 0.34
156 INT132881 Binding of INPP5K 7 0.48 4.35 0.33
157 INT179491 Transcription of Adipoq 4 0.51 0.98 0.32
158 INT119907 Binding of Inpp5k 3 0.33 0.6 0.32
159 INT188498 Negative_regulation of Transcription of Egr1 3 0.41 0.14 0.32
160 INT353695 Regulation of Negative_regulation of Slc8a1 1 0.36 0.38 0.32
161 INT293551 Regulation of Positive_regulation of Aqp1 1 0.13 0 0.31
162 INT91660 Positive_regulation of Positive_regulation of IL18 1 0.41 0.25 0.31
163 INT71292 Binding of Tf 5 0.27 1.58 0.3
164 INT227268 Negative_regulation of Transcription of Adipoq 4 0.52 4.93 0.3
165 INT102992 Regulation of Negative_regulation of SRD5A1 4 0.60 3.59 0.29
166 INT154074 Positive_regulation of Gene_expression of Tf 4 0.46 1.64 0.28
167 INT247097 Binding of CRHBP 3 0.34 0.4 0.28
168 INT153731 Positive_regulation of Gene_expression of Ahr 2 0.32 2 0.28
169 INT113421 Negative_regulation of Localization of IL18 2 0.58 0.87 0.27
170 INT55443 Positive_regulation of Positive_regulation of Ahr 1 0.40 0 0.26
171 INT268478 Negative_regulation of Positive_regulation of Igfbp5 1 0.26 0.64 0.26
172 INT117760 Regulation of Gene_expression of Cyp11a1 2 0.42 0.36 0.25
173 INT268477 Positive_regulation of Igfbp5 1 0.31 0.63 0.25
174 INT173164 Negative_regulation of INPP5K 4 0.51 2.01 0.24
175 INT126794 Binding of SRD5A1 2 0.36 3.26 0.22
176 INT253941 Positive_regulation of Localization of Adipoq 5 0.24 2.59 0.21
177 INT199771 Localization of Ahr 8 0.70 4.86 0.2
178 INT326607 Positive_regulation of STC1 1 0.20 3 0.2
179 INT104568 Negative_regulation of Localization of Aqp1 1 0.36 2.47 0.2
180 INT154282 Positive_regulation of Gene_expression of WT1 3 0.55 3.41 0.19
181 INT150529 Positive_regulation of Negative_regulation of Adipoq 2 0.37 1.76 0.18
182 INT312242 Binding of IGFBP5 2 0.08 0.69 0.18
183 INT165152 Gene_expression of Igfbp5 1 0.70 0.13 0.18
184 INT189310 Binding of STC1 1 0.26 0.73 0.18
185 INT119792 Negative_regulation of Localization of SLC8A1 1 0.01 0 0.18
186 INT197872 Regulation of Regulation of Adipoq 3 0.35 1.11 0.17
187 INT215814 Negative_regulation of Gene_expression of Aqp1 2 0.31 0.25 0.17
188 INT13723 Negative_regulation of Positive_regulation of WT1 1 0.03 1.26 0.17
189 INT10575 Positive_regulation of Transcription of Cyp11a1 1 0.05 0 0.17
190 INT102793 Regulation of Phosphorylation of Egr1 1 0.33 0 0.17
191 INT28026 Positive_regulation of Binding of Adipoq 1 0.27 0 0.17
192 INT228162 Negative_regulation of Localization of Adipoq 1 0.38 1.29 0.17
193 INT98625 Regulation of Aqp1 1 0.27 0.1 0.17
194 INT308978 Negative_regulation of Regulation of Adipoq 1 0.28 0.92 0.17
195 INT319048 Transcription of WT1 2 0.56 1.87 0.16
196 INT134193 Regulation of Regulation of Ahr 1 0.12 0.14 0.16
197 INT10572 Positive_regulation of Positive_regulation of Cyp11a1 1 0.05 0 0.16
198 INT289312 Phosphorylation of Ahr 1 0.03 0.86 0.15
199 INT195015 Negative_regulation of Positive_regulation of Slc8a1 1 0.04 0.31 0.15
200 INT294583 Negative_regulation of Gene_expression of Ahr 2 0.38 1.01 0.14
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