GO:0071339

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Name MLL1 complex
Categary Component
Go Slim No
Go Link GO:0071339
Unique Molecular Interactions 57
Total Molecular Interactions 78
Total Single Events 430
Pain Genes Associated 13

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for MLL1 complex. They are ordered first by their pain relevance and then by number of times they were reported for MLL1 complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT202959 Binding of BAG3 and MCRS1 1 0.11 7.46 3.14
2 INT85042 Binding of CCT6A and MAX 1 0.00 0 3.13
3 INT85041 Binding of IGHG3 and MAX 1 0.00 0 2.09
4 INT202958 Binding of STC2 and MCRS1 1 0.01 3.48 1.44
5 INT202960 Binding of MCRS1 and CPP 1 0.14 2.49 1.13
6 INT202968 Binding of MCRS1 and CAP1 1 0.03 2.46 1.08
7 INT85040 Positive_regulation of Binding of CCT6A and MAX 1 0.00 0 1.06
8 INT85039 Binding of GPM6A and MAX 1 0.00 0 1.05
9 INT202967 MCRS1 Negative_regulation of CPP 2 0.14 2.2 0.73
10 INT16048 MAX Positive_regulation of SLC25A4 1 0.50 0 0.71
11 INT202972 Positive_regulation of MCRS1 Negative_regulation of CPP 1 0.16 1.64 0.57
12 INT202961 MCRS1 Negative_regulation of STC2 1 0.00 1.63 0.57
13 INT168256 Binding of MLL and TNFRSF1B 1 0.00 1.2 0.53
14 INT202957 CPP Negative_regulation of MCRS1 1 0.14 1.53 0.51
15 INT156155 Binding of HCFC1 and TFAM 1 0.04 0.74 0.49
16 INT321598 Binding of MLL and TNF 1 0.05 1.07 0.49
17 INT202969 Positive_regulation of SGSM3 Positive_regulation of MCRS1 1 0.02 1.22 0.47
18 INT202964 SGSM3 Positive_regulation of MCRS1 1 0.03 1.21 0.47
19 INT344238 MCRS1 Regulation of TREX1 1 0.08 1.02 0.34
20 INT262307 CAPNS1 Regulation of TAF9 1 0.04 1.23 0.33
21 INT156149 Binding of HCFC1 and POU4F1 1 0.27 0.39 0.28
22 INT156154 POU4F1 Positive_regulation of HCFC1 1 0.36 0.38 0.28
23 INT156162 Binding of HCFC1 and CREB3 1 0.13 0.35 0.22
24 INT88698 Binding of Max and Cpm 1 0.00 0.27 0.18
25 INT88702 Binding of CPM and Max 1 0.01 0.27 0.18
26 INT325421 PHF20 Positive_regulation of Localization of Gnrhr 1 0.00 0.39 0.17
27 INT123194 Bmp6 Positive_regulation of TAF9 1 0.18 0.61 0.14
28 INT123193 Bmp6 Positive_regulation of Negative_regulation of TAF9 1 0.18 0.61 0.14
29 INT254133 PLEC Regulation of MCRS1 1 0.03 0.33 0.13
30 INT195662 Binding of PROC and KAT8 1 0.10 2.25 0.12
31 INT156161 Binding of HCFC1 and NFYC 1 0.02 0.36 0.12
32 INT232653 Binding of CD2 and MLL 1 0.02 0.27 0.1
33 INT215461 Binding of MLL and TNFSF13B 1 0.01 1.62 0.1
34 INT184889 Binding of ALOX5 and MCRS1 1 0.06 1.34 0.07
35 INT156144 MLL Positive_regulation of Epcam 1 0.00 0.47 0.06
36 INT338902 Binding of MAX and MYC 1 0.02 0.23 0.06
37 INT156143 MLL Positive_regulation of PECAM1 1 0.00 0.47 0.06
38 INT337118 MCRS1 Negative_regulation of C7orf49 1 0.00 0.66 0.04
39 INT236596 Ncoa2 Positive_regulation of PELP1 1 0.36 0.17 0.04
40 INT236595 Binding of Esr1 and PELP1 1 0.27 0.17 0.04
41 INT236597 Ncoa1 Positive_regulation of PELP1 1 0.41 0.17 0.03
42 INT191182 Binding of IRF1 and PRPF31 1 0.06 0.09 0.03
43 INT184887 MCRS1 Positive_regulation of ALOX5 1 0.11 0.64 0
44 INT182946 Binding of PELP1 and GSTK1 1 0.03 0.13 0
45 INT183017 Binding of PELP1 and Dre 1 0.01 0 0
46 INT225645 Binding of TAF1 and Acp5 1 0.01 0 0
47 INT238400 Binding of SRA1 and Positive_regulation of Negative_regulation of MAX 1 0.03 0.43 0
48 INT238389 SRA1 Positive_regulation of Negative_regulation of MAX 1 0.03 0.43 0
49 INT179091 Binding of Max and Myc 1 0.16 0.52 0
50 INT220821 Binding of MAX and Ctnnb1 1 0.09 0.13 0
51 INT252900 PTTG1 Regulation of Gene_expression of TAF9 1 0.20 0.84 0
52 INT189684 RNF2 Regulation of TERT 1 0.02 0.46 0
53 INT220766 Binding of MAX and LEF1 1 0.40 0.08 0
54 INT252893 PTTG1 Positive_regulation of Gene_expression of TAF9 1 0.21 0.9 0
55 INT186548 Binding of KRT1 and MAX 1 0.01 0.15 0
56 INT227843 Binding of ERCC6 and MLL 1 0.00 0.34 0
57 INT319026 Binding of Npc1 and Ruvbl1 1 0.00 0.08 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for MLL1 complex. They are ordered first by their pain relevance and then by number of times they were reported in MLL1 complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT72923 Positive_regulation of MCRS1 72 0.50 99.19 30.36
2 INT184895 Gene_expression of MCRS1 46 0.42 56.03 19.44
3 INT184890 Regulation of MCRS1 35 0.22 44.35 13.78
4 INT72924 Negative_regulation of MCRS1 27 0.19 33.59 10.29
5 INT175554 Binding of MCRS1 21 0.23 25.2 8.59
6 INT252968 Positive_regulation of TAF9 11 0.45 5.28 3.68
7 INT184894 Localization of MCRS1 9 0.47 10.04 3.31
8 INT66347 Gene_expression of MLL 29 0.65 14.82 3.18
9 INT252999 Gene_expression of TAF9 12 0.75 12.65 2.92
10 INT305617 Positive_regulation of Gene_expression of MCRS1 1 0.05 7.16 2.91
11 INT9119 Negative_regulation of TAF9 4 0.42 5.21 2.16
12 INT262317 Binding of TAF9 7 0.31 9.67 2.15
13 INT92415 Positive_regulation of Max 4 0.67 1.13 2.1
14 INT139459 Negative_regulation of MAX 6 0.57 0.32 1.79
15 INT305616 Negative_regulation of Gene_expression of MCRS1 1 0.04 3.56 1.23
16 INT202981 Positive_regulation of Binding of MCRS1 3 0.18 4.05 1.02
17 INT305620 Regulation of Positive_regulation of MCRS1 1 0.17 2.48 0.99
18 INT230779 Negative_regulation of Positive_regulation of MCRS1 2 0.04 3.78 0.92
19 INT11455 Regulation of MAX 6 0.44 2.49 0.56
20 INT139312 Negative_regulation of Gene_expression of MLL 2 0.00 1.22 0.56
21 INT323004 Transcription of TAF9 1 0.05 0.79 0.54
22 INT168257 Binding of MLL 4 0.02 4.25 0.53
23 INT92349 Positive_regulation of MAX 3 0.41 1.46 0.53
24 INT156166 Binding of HCFC1 4 0.33 1.85 0.51
25 INT78201 Regulation of MLL 2 0.02 0.79 0.48
26 INT305618 Regulation of Gene_expression of MCRS1 1 0.04 1.24 0.43
27 INT322997 Localization of TAF9 1 0.05 1.2 0.4
28 INT305619 Negative_regulation of Regulation of MCRS1 1 0.04 1.35 0.35
29 INT202982 Transcription of MCRS1 1 0.25 1.19 0.33
30 INT252969 Positive_regulation of Gene_expression of TAF9 5 0.67 5.22 0.32
31 INT232656 Localization of MLL 2 0.05 2.33 0.29
32 INT92416 Gene_expression of Max 2 0.36 0.81 0.27
33 INT230778 Positive_regulation of Positive_regulation of MCRS1 1 0.03 0.75 0.27
34 INT195678 Binding of KAT8 1 0.16 1.47 0.26
35 INT195676 Negative_regulation of KAT8 2 0.19 2.63 0.23
36 INT239796 Binding of TAF1 1 0.01 0.33 0.23
37 INT174663 Positive_regulation of KAT8 4 0.11 3.45 0.22
38 INT227872 Positive_regulation of MLL 7 0.01 2.44 0.19
39 INT174662 Regulation of KAT8 2 0.10 1.09 0.18
40 INT184892 Positive_regulation of Localization of MCRS1 2 0.22 1.24 0.16
41 INT103003 Gene_expression of MAX 10 0.75 1.03 0.13
42 INT27822 Negative_regulation of HCFC1 1 0.58 0.48 0.13
43 INT273890 Binding of Max 1 0.20 0.54 0.13
44 INT182981 Binding of PELP1 2 0.36 0.24 0.11
45 INT236594 Regulation of PELP1 1 0.44 0.24 0.11
46 INT236593 Regulation of Binding of PELP1 1 0.44 0.24 0.11
47 INT37939 Localization of MAX 2 0.73 1.22 0.1
48 INT252991 Regulation of TAF9 2 0.44 3.54 0.08
49 INT98254 Binding of MAX 1 0.36 0 0.05
50 INT182977 Positive_regulation of PELP1 3 0.49 0.34 0.04
51 INT319018 Binding of Ruvbl1 1 0.00 0.15 0.04
52 INT192280 Binding of PRPF31 1 0.36 0.25 0
53 INT182996 Positive_regulation of Binding of PELP1 1 0.17 0 0
54 INT292838 Gene_expression of TAF1 1 0.04 0.48 0
55 INT195675 Gene_expression of KAT8 1 0.30 1.38 0
56 INT160284 Negative_regulation of Gene_expression of MAX 1 0.41 0.07 0
57 INT258230 Negative_regulation of Negative_regulation of PELP1 1 0.11 0.16 0
58 INT319020 Regulation of Ruvbl1 1 0.00 0 0
59 INT193368 Gene_expression of HCFC1 1 0.29 0 0
60 INT184893 Negative_regulation of Binding of MCRS1 1 0.19 0.11 0
61 INT258251 Negative_regulation of PELP1 1 0.16 0.33 0
62 INT183006 Negative_regulation of Positive_regulation of PELP1 1 0.16 0 0
63 INT341085 Positive_regulation of Positive_regulation of MLL 1 0.01 0.15 0
64 INT186552 Positive_regulation of Gene_expression of MAX 1 0.49 0.21 0
65 INT319017 Positive_regulation of Ruvbl1 1 0.00 0 0
66 INT252984 Regulation of Gene_expression of TAF9 1 0.26 0.99 0
67 INT258236 Gene_expression of PELP1 1 0.18 0.06 0
68 INT174666 Localization of KAT8 1 0.11 0.05 0
69 INT319019 Protein_catabolism of Ruvbl1 1 0.01 0 0
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