GO:0071347

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Name cellular response to interleukin-1
Categary Process
Go Slim No
Go Link GO:0071347
Unique Molecular Interactions 1430
Total Molecular Interactions 2060
Total Single Events 20382
Pain Genes Associated 42

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cellular response to interleukin-1. They are ordered first by their pain relevance and then by number of times they were reported for cellular response to interleukin-1. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT182194 Binding of IL8 and CXCR2 10 0.56 7.14 4.16
2 INT61359 TNF Positive_regulation of NFKB1 11 0.63 6.66 3.89
3 INT87491 CALCA Positive_regulation of Gene_expression of IL8 1 0.72 0.92 3.52
4 INT180984 IRF6 Positive_regulation of Localization of IL8 7 0.11 2.13 3.47
5 INT149492 PNOC Negative_regulation of Gene_expression of CCL2 1 0.15 0.68 3.17
6 INT208572 Binding of IL8 and CXCR1 6 0.33 5.2 3.08
7 INT182635 Binding of CCR5 and CCL5 2 0.09 4.19 3
8 INT73821 CALCA Positive_regulation of Localization of IL8 1 0.25 2.37 2.91
9 INT318996 Binding of CCR3 and CCL5 1 0.07 3.39 2.9
10 INT319003 Binding of CCR1 and CCL5 1 0.08 3.38 2.89
11 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81
12 INT107322 Positive_regulation of TRPV1 Positive_regulation of Localization of IL8 3 0.13 1.64 2.5
13 INT149494 PNOC Negative_regulation of Gene_expression of CCL5 1 0.19 0.52 2.46
14 INT85252 Negative_regulation of Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.26
15 INT124121 IL6 Positive_regulation of CCL2 1 0.26 1.84 2.25
16 INT85251 Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.25
17 INT124120 IL6 Regulation of CCL2 1 0.15 1.8 2.22
18 INT128997 Cxcl1 Positive_regulation of Localization of Ccl2 1 0.72 1.54 2.16
19 INT81295 Ifng Positive_regulation of Gene_expression of Nos2 4 0.39 0.87 2.05
20 INT128996 Ccl2 Positive_regulation of Localization of Calca 1 0.68 1.43 2
21 INT91607 Binding of EDN1 and POMC 1 0.12 0 1.9
22 INT161224 Ccl2 Positive_regulation of Ccr2 1 0.52 2.09 1.88
23 INT201940 Binding of IL8 and CXCL10 2 0.28 2.46 1.86
24 INT205152 Binding of CD44 and MMP9 23 0.35 17.13 1.85
25 INT81920 Binding of IL1B and NFKB1 1 0.04 1.54 1.85
26 INT81914 Binding of HSF1 and NFKB1 1 0.05 1.54 1.85
27 INT267133 Binding of ICAM1 and VCAM1 25 0.32 25.43 1.83
28 INT155460 Tnfrsf1a Positive_regulation of Positive_regulation of Nfkb1 1 0.42 2.39 1.82
29 INT116092 TFF2 Positive_regulation of NFKB1 1 0.17 0.06 1.77
30 INT102160 Binding of Mmp2 and Mmp9 3 0.28 2.87 1.75
31 INT137207 Tnf Positive_regulation of Nfkb1 3 0.23 2.69 1.71
32 INT158302 Il23a Regulation of Gene_expression of Il17a 1 0.06 1.45 1.7
33 INT155459 Tnfrsf1a Positive_regulation of Nfkb1 1 0.42 2.45 1.63
34 INT136034 Edn1 Regulation of Trpv1 2 0.66 0.39 1.58
35 INT116093 OPRM1 Positive_regulation of Positive_regulation of NFKB1 1 0.36 0.08 1.56
36 INT151849 IL10 Negative_regulation of Gene_expression of IL8 4 0.14 3.26 1.54
37 INT256360 Car2 Positive_regulation of Localization of Rela 1 0.14 0 1.51
38 INT260897 CRH Positive_regulation of Localization of IL8 1 0.24 0.09 1.51
39 INT293013 IL8 Positive_regulation of Positive_regulation of CA2 1 0.12 0.66 1.49
40 INT106850 P2ry2 Positive_regulation of Phosphorylation of Creb1 2 0.49 0.73 1.36
41 INT178986 Binding of MMP9 and TIMP1 4 0.47 2.58 1.33
42 INT131256 Positive_regulation of Nfkb1 Positive_regulation of Gene_expression of Nfkbia 1 0.38 0.94 1.31
43 INT95275 Binding of Edn1 and Ece1 1 0.32 2.09 1.3
44 INT95274 Regulation of Binding of Edn1 and Ece1 1 0.39 2.09 1.3
45 INT112961 NGF Positive_regulation of ICAM1 1 0.40 0.96 1.28
46 INT177232 ICAM1 Regulation of Gene_expression of Vcam1 1 0.03 5.52 1.28
47 INT181436 Binding of Ccl2 and Eae1 1 0.05 5.14 1.27
48 INT254210 Binding of Cxcr2 and Ccl2 1 0.08 2.39 1.25
49 INT202042 CAMK2N2 Negative_regulation of MMP9 1 0.01 0.73 1.25
50 INT186355 Il23a Positive_regulation of Gene_expression of Il17a 4 0.12 3 1.24
51 INT151648 TLR4 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
52 INT151657 Vcam1 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
53 INT151658 F3 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
54 INT334129 Acsm3 Positive_regulation of Gene_expression of Icam1 1 0.22 2.89 1.22
55 INT62596 Binding of Edn1 and Nppa 1 0.27 1.77 1.22
56 INT200455 OPRK1 Positive_regulation of Gene_expression of CCL2 1 0.19 0.07 1.21
57 INT187172 RPS3AP9 Negative_regulation of MMP9 1 0.00 0.89 1.2
58 INT133046 TNF Positive_regulation of Positive_regulation of NFKB1 5 0.54 3.23 1.19
59 INT55162 Binding of NFKB1 and RELA 10 0.30 2.82 1.18
60 INT201067 Binding of Edn1 and Ednra 2 0.18 1.36 1.18
61 INT147447 ADCYAP1 Regulation of Localization of RELA 1 0.50 1.12 1.15
62 INT147448 ADCYAP1 Regulation of Localization of NFKB1 1 0.47 1.12 1.15
63 INT260810 Binding of CXCL10 and CCL2 1 0.10 1.37 1.12
64 INT83616 Binding of IL6 and IL8 5 0.09 5.8 1.11
65 INT101715 PLAT Positive_regulation of NFKB1 2 0.11 0.99 1.09
66 INT71176 Binding of ICAM1 and ITGB2 4 0.21 4.93 1.07
67 INT120313 Gnrhr Negative_regulation of Mmp2 1 0.03 0.85 1.07
68 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
69 INT139230 Icam1 Negative_regulation of Cmklr1 1 0.19 1.13 1.07
70 INT105113 Plat Positive_regulation of NFKB1 1 0.03 1.06 1.06
71 INT10238 Binding of EDN1 and Calca 1 0.00 1.07 1.06
72 INT139227 Icam1 Negative_regulation of Timp1 1 0.37 1.13 1.06
73 INT139225 Calca Negative_regulation of Icam1 1 0.44 1.13 1.06
74 INT139226 Icam1 Negative_regulation of Calca 1 0.44 1.12 1.05
75 INT181434 Binding of Ccr2 and Ccl2 1 0.27 6.06 1.04
76 INT88875 Ifng Positive_regulation of Transcription of Nos2 1 0.02 0.27 1.03
77 INT156245 NFKB1 Positive_regulation of Regulation of TNF 1 0.45 0.76 1.03
78 INT101381 POMC Regulation of Localization of IL8 1 0.28 1.49 1.02
79 INT74934 Regulation of IRF6 Positive_regulation of Nfkb1 1 0.01 0.52 1.02
80 INT352295 Binding of P2RY2 and Agtr1a 1 0.01 0.08 1.02
81 INT88887 IRF6 Positive_regulation of Transcription of Nos2 1 0.21 0.27 1.02
82 INT88874 Ifng Regulation of Nos2 1 0.01 0.26 1.01
83 INT293008 IL8 Positive_regulation of Localization of CA2 1 0.11 0.71 1.01
84 INT74933 IRF6 Positive_regulation of Nfkb1 1 0.02 0.52 1.01
85 INT88884 IRF6 Regulation of Nos2 1 0.12 0.26 1
86 INT88886 IRF6 Positive_regulation of Nos2 1 0.22 0.26 1
87 INT278946 IL6 Regulation of Gene_expression of IL8 1 0.20 1.9 1
88 INT88888 Regulation of IRF6 Positive_regulation of Nos2 1 0.20 0.26 1
89 INT61637 Binding of P2ry2 and Gtpbp4 1 0.02 0.1 0.99
90 INT209923 IL17A Negative_regulation of PPARA 1 0.14 2.46 0.99
91 INT103651 IL1B Positive_regulation of Gene_expression of IL8 6 0.78 1.23 0.98
92 INT167173 Binding of Ccl2 and Ccr2 2 0.30 1.15 0.98
93 INT311102 IL8 Positive_regulation of CXCR7 1 0.00 1.74 0.98
94 INT311143 IL8 Positive_regulation of Cxcr1 1 0.04 1.74 0.98
95 INT156508 Nfkb1 Regulation of Positive_regulation of Grin1 1 0.22 0.98 0.98
96 INT187111 TIMP2 Regulation of MMP9 1 0.23 1.47 0.97
97 INT103133 TNF Positive_regulation of Gene_expression of IL8 2 0.48 1.26 0.96
98 INT278940 LEP Positive_regulation of Gene_expression of IL8 1 0.34 1.68 0.96
99 INT256357 Phosphorylation of Rela Positive_regulation of Localization of Ik 1 0.00 0.05 0.96
100 INT135585 CSF2 Regulation of CCL2 1 0.13 2.51 0.95
101 INT182190 Binding of IL8 and CXCR4 1 0.26 1.25 0.95
102 INT136033 Edn1 Positive_regulation of Trpv1 1 0.50 0.34 0.95
103 INT133050 TNF Positive_regulation of Gene_expression of ICAM1 3 0.67 1.91 0.94
104 INT77859 EDN1 Positive_regulation of MC1R 2 0.64 0.34 0.94
105 INT266659 Binding of MMP9 and MOCS1 1 0.01 1.71 0.94
106 INT152388 Binding of NFKB1 and OPRM1 1 0.04 0.14 0.94
107 INT299988 IL6 Positive_regulation of Localization of IL8 1 0.05 0.81 0.94
108 INT182206 Binding of CXCR5 and IL8 1 0.30 1.25 0.94
109 INT152389 Negative_regulation of Binding of NFKB1 and OPRM1 1 0.05 0.14 0.94
110 INT182196 Binding of IL8 and CXCL13 1 0.27 1.24 0.93
111 INT129003 Ccl2 Positive_regulation of ANTXRL 1 0.00 0.68 0.92
112 INT289461 IRF6 Positive_regulation of ICAM1 1 0.08 0.61 0.91
113 INT250976 Binding of FMOD and IL8 1 0.08 1.26 0.91
114 INT221386 Tlr4 Positive_regulation of Gene_expression of IL8 6 0.14 3.53 0.9
115 INT256646 Tnf Positive_regulation of Positive_regulation of Nfkb1 1 0.22 1.83 0.9
116 INT346266 MTX1 Regulation of IL17A 1 0.08 1.33 0.89
117 INT108687 Nfkb1 Regulation of Positive_regulation of Nos2 1 0.50 1.28 0.88
118 INT318462 Nnat Positive_regulation of Nfkb1 1 0.46 0.9 0.88
119 INT152694 Negative_regulation of Nfkb1 Negative_regulation of Bdnf 1 0.24 0.15 0.88
120 INT152697 Nfkb1 Negative_regulation of Ltp 1 0.04 0.15 0.88
121 INT62956 CXCR2 Positive_regulation of IL8 1 0.30 0 0.88
122 INT108686 Nfkb1 Regulation of Nos2 1 0.69 1.27 0.88
123 INT152695 Nfkb1 Negative_regulation of Bdnf 1 0.24 0.15 0.88
124 INT90387 ROS1 Positive_regulation of NFKB1 4 0.32 2.35 0.87
125 INT96811 Nfkb1 Regulation of Gene_expression of IK 1 0.00 1.06 0.87
126 INT116555 Olr1627 Negative_regulation of Positive_regulation of Nfkb1 1 0.02 1.51 0.86
127 INT186672 IL8 Positive_regulation of Transcription of PTH 1 0.01 1.83 0.85
128 INT196578 Ephb1 Positive_regulation of Phosphorylation of Mapk9 1 0.13 0.5 0.85
129 INT196576 Trib3 Positive_regulation of Phosphorylation of Mapk9 1 0.02 0.5 0.85
130 INT116557 Olr1627 Negative_regulation of Localization of Nfkb1 1 0.02 1.51 0.85
131 INT146919 Tnf Positive_regulation of Gene_expression of Ccl2 1 0.16 1.44 0.84
132 INT302379 Crp Positive_regulation of Gene_expression of Ccl2 1 0.10 4.58 0.84
133 INT287494 CRP Positive_regulation of Gene_expression of CCL2 2 0.30 2.33 0.83
134 INT334132 Acsm3 Positive_regulation of Gene_expression of Cxcl2 1 0.13 2.26 0.83
135 INT149561 Tgfb1 Positive_regulation of Gene_expression of CCL2 1 0.00 0 0.83
136 INT116558 Ptpn5 Positive_regulation of Nfkb1 1 0.46 2.01 0.83
137 INT161305 NFKB1 Positive_regulation of IL2 1 0.25 0.25 0.83
138 INT102931 Nos3 Positive_regulation of Nos2 1 0.43 1.63 0.83
139 INT106312 NFKB1 Regulation of S100A4 1 0.14 1.1 0.83
140 INT149563 Tgfb1 Positive_regulation of CCL2 1 0.00 0 0.83
141 INT106859 EDN1 Positive_regulation of Transcription of MC1R 1 0.22 0 0.82
142 INT149557 Tgfb1 Positive_regulation of Gene_expression of Ccl5 1 0.00 0 0.82
143 INT66206 Negative_regulation of TNF Positive_regulation of NFKB1 2 0.53 1.71 0.81
144 INT87490 CALCA Positive_regulation of Gene_expression of CCL5 1 0.30 0.14 0.81
145 INT87494 CALCA Positive_regulation of IL8 1 0.48 0.15 0.81
146 INT88885 IRF6 Positive_regulation of Gene_expression of Nos2 1 0.21 0.1 0.81
147 INT88878 Negative_regulation of Nfkb1 Positive_regulation of Gene_expression of Nos2 1 0.06 0.1 0.81
148 INT87489 CALCA Positive_regulation of Gene_expression of CCL2 1 0.43 0.14 0.81
149 INT87492 CALCA Regulation of IL8 1 0.28 0.15 0.81
150 INT286346 IRF6 Positive_regulation of IL8 3 0.03 0.88 0.8
151 INT219911 Edn1 Regulation of Gene_expression of Trpv1 1 0.23 0.57 0.8
152 INT140966 NFKB1 Positive_regulation of Positive_regulation of CPOX 1 0.08 0.66 0.8
153 INT104831 Binding of GLI2 and NFKB1 1 0.08 0 0.8
154 INT239671 Binding of Ccl2 and Gtf3a 1 0.02 1.34 0.79
155 INT196525 Binding of MMP2 and MMP9 2 0.32 2.49 0.78
156 INT102163 Binding of TNF and Mmp9 1 0.12 0.88 0.78
157 INT102161 Binding of TNF and Mmp2 1 0.10 0.88 0.78
158 INT182814 Binding of ICAM1 and PECAM1 2 0.02 3.32 0.77
159 INT207391 Il17a Positive_regulation of Gene_expression of Tnfsf11 2 0.05 1.19 0.77
160 INT149493 PNOC Negative_regulation of CCL5 1 0.14 0.16 0.77
161 INT149495 PNOC Negative_regulation of CCL2 1 0.11 0.16 0.77
162 INT102159 Binding of Adam17 and Mmp2 1 0.18 0.87 0.77
163 INT87493 Binding of CALCA and Positive_regulation of Gene_expression of IL8 1 0.52 0.18 0.76
164 INT90118 Jun Regulation of Gene_expression of Nfkb1 1 0.18 0.39 0.76
165 INT90125 Nfkb1 Regulation of Gene_expression of Nos1 1 0.17 0.39 0.76
166 INT90116 Nfkb1 Positive_regulation of Gene_expression of Nos1 1 0.32 0.39 0.76
167 INT90122 Nfkb1 Positive_regulation of Gene_expression of Fos 1 0.39 0.39 0.75
168 INT128815 Mapk14 Regulation of Gene_expression of Nos2 1 0.21 0.46 0.74
169 INT258644 Binding of CCL2 and CCL5 1 0.36 1.6 0.74
170 INT295711 MMP9 Positive_regulation of Localization of VEGFA 1 0.06 0.29 0.74
171 INT258643 Positive_regulation of Binding of CCL2 and CCL5 1 0.49 1.61 0.74
172 INT176479 IL17A Positive_regulation of Gene_expression of TIMP1 1 0.02 1.33 0.74
173 INT128813 Mapk8 Regulation of Gene_expression of Nos2 1 0.23 0.46 0.74
174 INT209048 Il3 Positive_regulation of Il17a 1 0.03 0.38 0.73
175 INT209052 Il2 Positive_regulation of Il17a 1 0.03 0.38 0.73
176 INT209034 Il4 Positive_regulation of Il17a 1 0.04 0.38 0.73
177 INT228494 Binding of Ncoa5 and Rela 1 0.00 1.58 0.72
178 INT209039 Il6 Positive_regulation of Il17a 1 0.05 0.38 0.72
179 INT209028 Il12b Positive_regulation of Il17a 1 0.12 0.37 0.72
180 INT248244 Binding of IL8 and SDC2 1 0.02 1.57 0.72
181 INT209044 Il10 Positive_regulation of Il17a 1 0.05 0.37 0.72
182 INT146463 TNFSF10 Positive_regulation of NFKB1 2 0.08 2.45 0.71
183 INT216654 Binding of P2ry2 and DRGX 1 0.01 1.59 0.71
184 INT64117 Binding of Edn1 and Ins1 1 0.06 0.85 0.71
185 INT146461 IFNG Positive_regulation of NFKB1 1 0.01 1.44 0.71
186 INT222493 Edn1 Positive_regulation of Localization of Prl 1 0.10 0 0.71
187 INT153123 NFKBIA Negative_regulation of Phosphorylation of RELA 1 0.03 2.01 0.71
188 INT267630 Il1 Regulation of Gene_expression of IL8 1 0.00 0.44 0.71
189 INT103134 DCSTAMP Positive_regulation of NFKB1 2 0.07 1.43 0.7
190 INT120018 VEGFA Positive_regulation of CCL3 1 0.01 1 0.7
191 INT120017 CCL2 Positive_regulation of CCL3 1 0.01 0.99 0.7
192 INT120020 VEGFA Positive_regulation of CCL2 1 0.00 1 0.7
193 INT120035 CCL2 Positive_regulation of Prap1 1 0.00 0.99 0.7
194 INT63557 Binding of Edn1 and Edn3 1 0.23 0.63 0.7
195 INT120037 IL8 Positive_regulation of Prap1 1 0.00 0.99 0.7
196 INT295720 PTGER2 Regulation of MMP9 1 0.01 0.53 0.7
197 INT120019 IL8 Positive_regulation of CCL3 1 0.02 0.99 0.7
198 INT187522 ATIC Negative_regulation of Gene_expression of Nos2 1 0.02 1.46 0.7
199 INT278956 LEP Regulation of Gene_expression of IL8 1 0.30 1.11 0.69
200 INT263049 Positive_regulation of Binding of Mmp2 and Mmp9 1 0.35 0.83 0.69

Single Events

The table below shows the top 100 pain related interactions that have been reported for cellular response to interleukin-1. They are ordered first by their pain relevance and then by number of times they were reported in cellular response to interleukin-1. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT10832 Gene_expression of IL8 1050 0.78 698.72 270
2 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08
3 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02
4 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87
5 INT65054 Positive_regulation of Nfkb1 285 0.70 149.33 126.73
6 INT12339 Localization of IL8 437 0.81 251.87 117.39
7 INT118381 Gene_expression of Il17a 405 0.76 306.97 112.06
8 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62
9 INT82878 Gene_expression of Ccl2 201 0.78 164.95 101.35
10 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6
11 INT54571 Positive_regulation of NFKB1 263 0.70 138.99 87.32
12 INT48406 Gene_expression of Icam1 277 0.78 238.28 81.71
13 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53
14 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34
15 INT102546 Gene_expression of Ccl2 197 0.78 192.8 67.41
16 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85
17 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81
18 INT78899 Gene_expression of CCL5 155 0.77 84.02 55.09
19 INT48952 Negative_regulation of Nos2 204 0.59 101.73 53.15
20 INT49017 Negative_regulation of Gene_expression of Nos2 169 0.59 80.64 52.67
21 INT5781 Gene_expression of Edn1 190 0.78 99.1 46
22 INT145266 Gene_expression of IL17A 154 0.75 109.83 45.33
23 INT81498 Positive_regulation of Gene_expression of CCL2 107 0.70 53.89 45.22
24 INT82883 Positive_regulation of Ccl2 105 0.69 84.96 42.27
25 INT68975 Gene_expression of Mmp9 111 0.78 79.57 38.55
26 INT48222 Positive_regulation of Localization of IL8 123 0.59 78.04 37.2
27 INT62827 Positive_regulation of ICAM1 184 0.70 180.95 36.28
28 INT51017 Positive_regulation of Icam1 113 0.70 81.16 35.55
29 INT65055 Negative_regulation of Nfkb1 83 0.58 44.85 34.94
30 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19
31 INT65536 Negative_regulation of Positive_regulation of Nfkb1 77 0.59 38.86 33.33
32 INT65698 Localization of CCL2 118 0.81 77.54 32.69
33 INT99610 Localization of MMP9 126 0.79 48.46 32.67
34 INT81530 Gene_expression of Nfkb1 93 0.78 48.58 32.58
35 INT84170 Positive_regulation of Gene_expression of Ccl2 58 0.69 48.79 32.43
36 INT29503 Gene_expression of Mmp2 95 0.77 56.92 31.68
37 INT77652 Negative_regulation of Gene_expression of IL8 99 0.59 67.57 30.21
38 INT68973 Positive_regulation of Mmp9 89 0.52 58.56 30.04
39 INT56072 Negative_regulation of NFKB1 94 0.59 53.16 28.19
40 INT82882 Localization of Ccl2 61 0.80 41.96 28
41 INT73047 Positive_regulation of MMP9 133 0.68 73.22 26.42
42 INT65537 Positive_regulation of Positive_regulation of Nfkb1 52 0.67 30.6 26.35
43 INT61953 Transcription of Nos2 101 0.72 46.64 25.49
44 INT10836 Negative_regulation of IL8 95 0.59 52.59 24.71
45 INT10835 Regulation of IL8 79 0.49 53.04 24.14
46 INT6726 Positive_regulation of Edn1 118 0.70 65.96 24.07
47 INT70503 Regulation of Gene_expression of Nos2 71 0.62 44 24.01
48 INT37889 Gene_expression of P2ry2 75 0.65 26.01 23.8
49 INT55170 Gene_expression of NFKB1 97 0.77 52.75 23.04
50 INT66208 Positive_regulation of Positive_regulation of NFKB1 45 0.68 20.17 22.62
51 INT150022 Positive_regulation of Il17a 69 0.64 70.04 21.87
52 INT74682 Positive_regulation of Mmp2 72 0.69 40.46 21.73
53 INT48407 Positive_regulation of Gene_expression of Icam1 61 0.70 57.91 21.54
54 INT52106 Negative_regulation of Localization of IL8 57 0.52 22.81 20.8
55 INT614 Gene_expression of Cxcl2 29 0.76 25.53 20.8
56 INT63340 Positive_regulation of Gene_expression of ICAM1 109 0.70 90.82 20.61
57 INT78901 Localization of CCL5 67 0.78 40.79 20.59
58 INT8662 Positive_regulation of EDN1 144 0.70 125.34 19.59
59 INT138696 Positive_regulation of Ccl2 57 0.67 59.57 19.58
60 INT5048 Binding of Edn1 55 0.47 18.86 19.16
61 INT101188 Gene_expression of Rela 81 0.56 23.43 19.15
62 INT89594 Gene_expression of Ccl5 44 0.54 24.08 18.62
63 INT10833 Regulation of Gene_expression of IL8 68 0.62 38.74 18.46
64 INT66857 Regulation of CCL2 39 0.53 28.55 18.35
65 INT84171 Negative_regulation of Gene_expression of Ccl2 30 0.58 26.37 18.28
66 INT55880 Negative_regulation of Gene_expression of CCL2 49 0.59 22.37 18.09
67 INT71680 Gene_expression of CCL3 43 0.75 33.7 18.01
68 INT55878 Regulation of Gene_expression of CCL2 34 0.62 15.71 17.97
69 INT113602 Positive_regulation of Gene_expression of Ccl2 48 0.70 48.71 17.85
70 INT62826 Negative_regulation of Gene_expression of ICAM1 75 0.58 46.39 17.72
71 INT61949 Regulation of Nos2 74 0.58 34.08 16.7
72 INT10834 Binding of IL8 65 0.48 41.66 16.53
73 INT25517 Regulation of NFKB1 41 0.61 22.28 16.09
74 INT52107 Transcription of IL8 63 0.72 41.66 16.06
75 INT103245 Positive_regulation of Gene_expression of MMP9 64 0.68 36.86 15.7
76 INT54572 Negative_regulation of Positive_regulation of NFKB1 46 0.58 21.45 15.47
77 INT93482 Localization of Rela 56 0.78 24.52 14.82
78 INT153776 Positive_regulation of IL17A 42 0.64 34.58 14.82
79 INT9191 Localization of EDN1 94 0.81 57.01 14.78
80 INT61635 Positive_regulation of P2ry2 35 0.56 12.08 14.68
81 INT105387 Gene_expression of HIF1A 116 0.77 98.62 14.66
82 INT8904 Positive_regulation of Gene_expression of EDN1 66 0.70 65.4 14.42
83 INT39733 Localization of NFKB1 59 0.79 22.76 13.99
84 INT91544 Gene_expression of CHI3L1 60 0.75 77.72 13.9
85 INT5806 Regulation of Edn1 63 0.62 23.46 13.88
86 INT6365 Localization of Edn1 56 0.81 18.84 13.83
87 INT161515 Positive_regulation of Gene_expression of Il17a 50 0.64 41.52 13.82
88 INT78480 Localization of Nfkb1 39 0.80 23.14 13.64
89 INT144646 Positive_regulation of Rela 53 0.67 27.78 13.2
90 INT55168 Binding of NFKB1 55 0.48 22.94 13.15
91 INT21979 Negative_regulation of EDN1 52 0.58 24.65 12.55
92 INT96850 Negative_regulation of CCL2 42 0.59 24.89 12.55
93 INT93715 Negative_regulation of MMP9 69 0.55 36.05 11.73
94 INT65057 Regulation of Nfkb1 28 0.47 16.48 11.62
95 INT65713 Localization of ICAM1 42 0.81 39.55 11.49
96 INT68976 Positive_regulation of Gene_expression of Mmp9 34 0.42 28.21 11.28
97 INT48956 Negative_regulation of Positive_regulation of Nos2 34 0.46 13.15 11.15
98 INT81531 Positive_regulation of Gene_expression of Nfkb1 27 0.69 13.9 11.04
99 INT56448 Regulation of ICAM1 52 0.60 55.1 10.96
100 INT74681 Positive_regulation of Gene_expression of Mmp2 23 0.55 15.58 10.74
101 INT4240 Positive_regulation of CCL5 32 0.58 20.55 10.65
102 INT100379 Positive_regulation of HIF1A 69 0.69 57.31 10.4
103 INT89282 Regulation of MMP9 39 0.60 25.45 10.34
104 INT160563 Localization of Il17a 34 0.74 26.53 10.24
105 INT78895 Regulation of CCL5 30 0.46 20.45 10.18
106 INT56450 Negative_regulation of Gene_expression of Icam1 33 0.52 27.21 10.15
107 INT10184 Regulation of EDN1 44 0.62 23.78 10.06
108 INT65058 Binding of Nfkb1 36 0.45 19.87 10.02
109 INT140338 Negative_regulation of Gene_expression of Il17a 34 0.46 23.82 9.87
110 INT83450 Positive_regulation of Localization of CCL2 28 0.70 22.14 9.83
111 INT126031 Negative_regulation of Gene_expression of MMP9 40 0.57 22.71 9.79
112 INT106200 Binding of Ccl2 22 0.42 16.7 9.75
113 INT80549 Binding of ICAM1 53 0.47 42.76 9.72
114 INT70850 Positive_regulation of Transcription of Nos2 30 0.70 18.95 9.68
115 INT105816 Gene_expression of P2RY2 53 0.78 16.47 9.67
116 INT63341 Negative_regulation of ICAM1 42 0.59 30.45 9.5
117 INT87495 Positive_regulation of Gene_expression of CCL5 26 0.69 13.85 9.46
118 INT135407 Negative_regulation of Ccl2 33 0.57 32.74 9.45
119 INT140224 Localization of Ccl2 32 0.72 26.91 9.39
120 INT125247 Negative_regulation of Mmp9 42 0.43 23.68 9.37
121 INT138700 Negative_regulation of Gene_expression of Ccl2 27 0.57 24.1 9.08
122 INT63338 Regulation of Gene_expression of ICAM1 42 0.62 28.26 9.06
123 INT187190 Positive_regulation of Localization of MMP9 27 0.68 8.1 8.93
124 INT66213 Localization of RELA 63 0.78 14.71 8.77
125 INT10237 Binding of EDN1 40 0.48 16 8.48
126 INT72337 Positive_regulation of Positive_regulation of Nos2 37 0.65 17.02 8.11
127 INT111903 Regulation of Mmp2 9 0.61 3.95 7.98
128 INT62944 Regulation of Icam1 33 0.47 23.52 7.94
129 INT48404 Regulation of Gene_expression of Icam1 21 0.62 15.1 7.81
130 INT121977 Phosphorylation of Nfkb1 15 0.51 9.83 7.77
131 INT116552 Positive_regulation of Localization of Nfkb1 16 0.61 12.7 7.74
132 INT10899 Positive_regulation of Gene_expression of Edn1 32 0.70 24.88 7.65
133 INT81537 Regulation of Gene_expression of Nfkb1 10 0.57 7.09 7.48
134 INT89589 Negative_regulation of Ccl5 9 0.40 4.62 7.39
135 INT76253 Positive_regulation of P2RY2 29 0.70 13.99 7.33
136 INT10104 Negative_regulation of Edn1 43 0.59 15.63 7.2
137 INT82881 Regulation of Ccl2 19 0.57 15.29 7.19
138 INT155010 Positive_regulation of Gene_expression of IL17A 23 0.64 20.17 7.15
139 INT66210 Regulation of Positive_regulation of NFKB1 16 0.60 9.46 7.08
140 INT95466 Regulation of P2ry2 23 0.56 3.66 6.86
141 INT81493 Transcription of CCL2 20 0.65 13.63 6.78
142 INT256345 Phosphorylation of Rela 21 0.75 9.51 6.56
143 INT120895 Binding of CCL2 22 0.37 15.86 6.55
144 INT65538 Regulation of Positive_regulation of Nfkb1 17 0.51 8.31 6.5
145 INT228469 Negative_regulation of Il17a 19 0.54 18.76 6.43
146 INT92504 Negative_regulation of Ccl2 17 0.43 8.98 6.29
147 INT75832 Positive_regulation of Positive_regulation of IL8 30 0.70 20.77 6.05
148 INT152293 Regulation of Mmp9 9 0.49 6.57 6.01
149 INT74422 Regulation of Localization of IL8 21 0.62 10.19 5.99
150 INT115947 Regulation of Il17a 17 0.37 14.26 5.97
151 INT92470 Negative_regulation of Gene_expression of CCL5 15 0.50 5.46 5.86
152 INT71727 Negative_regulation of Icam1 25 0.45 17.76 5.73
153 INT75833 Negative_regulation of Positive_regulation of IL8 15 0.53 6.69 5.59
154 INT83290 Regulation of Gene_expression of Ccl2 8 0.59 9.06 5.56
155 INT87468 Negative_regulation of Mmp2 24 0.57 10.79 5.55
156 INT65712 Positive_regulation of Localization of ICAM1 14 0.70 16.72 5.5
157 INT99606 Negative_regulation of Localization of MMP9 23 0.57 7.15 5.47
158 INT112713 Gene_expression of Hif1a 24 0.75 20.48 5.45
159 INT140223 Regulation of Ccl2 15 0.45 13.1 5.41
160 INT92398 Negative_regulation of Localization of Nfkb1 17 0.42 11.24 5.4
161 INT78728 Negative_regulation of Binding of NFKB1 18 0.58 6.89 5.39
162 INT66209 Negative_regulation of Localization of NFKB1 23 0.58 8.2 5.31
163 INT173584 Localization of IL17A 14 0.74 10.83 5.19
164 INT73608 Localization of Nos2 21 0.75 9.58 5.05
165 INT66211 Positive_regulation of Localization of NFKB1 20 0.68 8.18 5.01
166 INT75831 Positive_regulation of Transcription of IL8 21 0.63 13.56 4.98
167 INT161220 Binding of Ccl2 17 0.46 17.63 4.94
168 INT82887 Positive_regulation of Ccl5 10 0.40 3.4 4.91
169 INT61950 Regulation of Positive_regulation of Nos2 17 0.43 9.01 4.87
170 INT92505 Negative_regulation of Cxcl2 5 0.57 2.09 4.75
171 INT103073 Positive_regulation of Positive_regulation of Ccl2 10 0.50 6.74 4.7
172 INT89590 Negative_regulation of Gene_expression of Ccl5 8 0.36 3.97 4.67
173 INT29502 Localization of Mmp2 18 0.79 3.49 4.64
174 INT96851 Negative_regulation of Localization of CCL2 14 0.53 5.98 4.57
175 INT55171 Gene_expression of RELA 80 0.75 17.17 4.47
176 INT125884 Positive_regulation of CHI3L1 15 0.62 34.04 4.43
177 INT75440 Regulation of Binding of Edn1 4 0.38 1.41 4.33
178 INT4239 Negative_regulation of CCL5 15 0.40 10.92 4.26
179 INT89784 Regulation of Transcription of Nos2 14 0.42 8.39 4.24
180 INT112704 Positive_regulation of Hif1a 25 0.67 21.49 4.23
181 INT93483 Negative_regulation of Localization of Rela 11 0.57 5.1 4.19
182 INT125896 Negative_regulation of Gene_expression of Mmp9 15 0.43 13.73 4.18
183 INT79234 Positive_regulation of CCL3 15 0.67 11.43 4.15
184 INT99608 Transcription of MMP9 18 0.65 9.67 4.11
185 INT158377 Positive_regulation of Positive_regulation of Rela 6 0.49 3.08 4.11
186 INT235510 Binding of Il17a 14 0.34 10.67 3.99
187 INT56077 Protein_catabolism of NFKB1 16 0.98 8.03 3.94
188 INT68255 Regulation of Positive_regulation of IL8 12 0.41 5.71 3.91
189 INT118583 Positive_regulation of IRF1 10 0.68 3.75 3.91
190 INT84852 Transcription of Nfkb1 12 0.67 4.28 3.84
191 INT133312 Binding of MMP9 25 0.42 16.79 3.83
192 INT56075 Transcription of NFKB1 13 0.71 9.03 3.83
193 INT70996 Positive_regulation of Positive_regulation of Icam1 8 0.60 6.02 3.74
194 INT133550 Negative_regulation of Gene_expression of Rela 14 0.40 4.64 3.73
195 INT112340 Gene_expression of Cyp11a1 11 0.77 5.19 3.7
196 INT103281 Transcription of CCL5 10 0.67 5.95 3.7
197 INT71885 Protein_catabolism of Nfkb1 8 0.53 5.34 3.69
198 INT79231 Positive_regulation of Gene_expression of NFKB1 18 0.67 9.16 3.66
199 INT155011 Negative_regulation of IL17A 8 0.54 6.43 3.64
200 INT134149 Negative_regulation of Gene_expression of NFKB1 7 0.55 4.25 3.63
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