GO:0071354

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Name cellular response to interleukin-6
Categary Process
Go Slim No
Go Link GO:0071354
Unique Molecular Interactions 25
Total Molecular Interactions 29
Total Single Events 411
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cellular response to interleukin-6. They are ordered first by their pain relevance and then by number of times they were reported for cellular response to interleukin-6. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT187101 Selp Regulation of Sele 1 0.20 1.23 0.53
2 INT96103 Binding of PPBP and Selp 1 0.00 1.22 0.46
3 INT96095 Binding of Selp and Pf4 1 0.01 1.2 0.45
4 INT99015 Binding of Selp and Vcam1 2 0.27 1.76 0.35
5 INT322045 Gp6 Positive_regulation of Gene_expression of Selp 1 0.04 0.15 0.33
6 INT96096 Binding of Serpinc1 and Selp 1 0.00 0.69 0.3
7 INT96102 Binding of TAT and Selp 1 0.04 0.7 0.3
8 INT96094 Binding of Selp and F2 1 0.00 0.67 0.29
9 INT99010 Selp Regulation of Vcam1 1 0.20 1.35 0.18
10 INT99014 Binding of Sell and Selp 1 0.13 1.35 0.18
11 INT99008 Regulation of Binding of Selp and Vcam1 1 0.33 1.36 0.18
12 INT99009 Regulation of Binding of Sell and Selp 1 0.15 1.36 0.18
13 INT336751 Binding of Selp and Cd40 1 0.03 2.49 0.18
14 INT99013 Binding of Itgb2 and Selp 1 0.16 1.36 0.18
15 INT99006 Regulation of Binding of Selp and Itga1 1 0.06 1.36 0.18
16 INT99012 Binding of Selp and Itga1 1 0.05 1.36 0.18
17 INT99011 Regulation of Binding of Itgb2 and Selp 1 0.19 1.37 0.18
18 INT281307 Binding of Selp and Selplg 1 0.01 0.76 0.17
19 INT214480 SELPLG Negative_regulation of Positive_regulation of NFKB1 1 0.00 0.6 0.14
20 INT204877 gr Negative_regulation of Serpina3n 1 0.23 0.15 0.1
21 INT201618 Uvbi1 Positive_regulation of Phb 1 0.04 0.28 0.09
22 INT213392 Binding of SELPLG and XPO1 1 0.02 0.31 0.04
23 INT341043 Avp Regulation of Camp 1 0.10 0.47 0.03
24 INT213390 Positive_regulation of Binding of CHKB and SELPLG 1 0.01 0.46 0
25 INT213393 Binding of CHKB and SELPLG 1 0.01 0.46 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cellular response to interleukin-6. They are ordered first by their pain relevance and then by number of times they were reported in cellular response to interleukin-6. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT49141 Gene_expression of Selp 157 0.78 85.22 24.78
2 INT63169 Positive_regulation of Gene_expression of Selp 35 0.69 21.95 7.16
3 INT63170 Positive_regulation of Selp 27 0.68 24.1 6.3
4 INT99001 Negative_regulation of Selp 23 0.59 16.68 4.74
5 INT117551 Regulation of Gene_expression of Selp 15 0.44 7.32 4.2
6 INT9256 Gene_expression of SELPLG 30 0.75 16.44 3.66
7 INT130557 Negative_regulation of Gene_expression of Selp 17 0.54 6.56 3.45
8 INT156579 Localization of Selp 14 0.73 6.53 2.69
9 INT96084 Binding of Selp 12 0.48 8.41 2.16
10 INT9257 Positive_regulation of SELPLG 5 0.45 3.57 1.16
11 INT98994 Regulation of Selp 10 0.45 3.91 0.83
12 INT41106 Gene_expression of Camp 2 0.75 0.24 0.64
13 INT41105 Regulation of Gene_expression of Camp 1 0.44 0 0.64
14 INT187088 Regulation of Negative_regulation of Selp 1 0.31 1.07 0.61
15 INT157576 Positive_regulation of Localization of Selp 2 0.49 1.19 0.59
16 INT136325 Negative_regulation of Binding of Selp 2 0.59 2.26 0.42
17 INT9258 Positive_regulation of Gene_expression of SELPLG 1 0.45 0.95 0.42
18 INT12169 Gene_expression of Serpina3n 2 0.48 3.44 0.34
19 INT214504 Localization of SELPLG 2 0.23 0.88 0.2
20 INT213407 Binding of SELPLG 2 0.07 2.98 0.2
21 INT173720 Regulation of Serpina3n 1 0.14 0.52 0.13
22 INT311578 Positive_regulation of Positive_regulation of SELPLG 1 0.18 0.57 0.12
23 INT200609 Regulation of Localization of Selp 1 0.20 0.64 0.07
24 INT213400 Regulation of SELPLG 4 0.14 3.53 0.05
25 INT178482 Regulation of Positive_regulation of Selp 1 0.04 1.38 0.05
26 INT204876 Localization of Serpina3n 1 0.73 0.09 0.04
27 INT213399 Negative_regulation of SELPLG 3 0.16 3.23 0.03
28 INT341036 Regulation of Camp 1 0.44 0.42 0.03
29 INT213398 Regulation of Gene_expression of SELPLG 2 0.04 0.23 0
30 INT329372 Negative_regulation of Gene_expression of SELPLG 1 0.16 1.74 0
31 INT214512 Transcription of SELPLG 1 0.14 0.16 0
32 INT214515 Regulation of Transcription of SELPLG 1 0.09 0.16 0
33 INT156580 Negative_regulation of Localization of Selp 1 0.06 0.13 0
34 INT243078 Gene_expression of Phb 1 0.42 0.09 0
35 INT341040 Negative_regulation of Camp 1 0.42 0.36 0
36 INT341041 Localization of Camp 1 0.73 0.06 0
37 INT341038 Protein_catabolism of Camp 1 0.64 0 0
38 INT341037 Negative_regulation of Gene_expression of Camp 1 0.42 0 0
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