GO:0071356

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Name cellular response to tumor necrosis factor
Categary Process
Go Slim No
Go Link GO:0071356
Unique Molecular Interactions 1114
Total Molecular Interactions 1648
Total Single Events 16293
Pain Genes Associated 42

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cellular response to tumor necrosis factor. They are ordered first by their pain relevance and then by number of times they were reported for cellular response to tumor necrosis factor. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT182194 Binding of IL8 and CXCR2 10 0.56 7.14 4.16
2 INT69032 IL18 Positive_regulation of IFNA1 12 0.23 7.87 3.83
3 INT87491 CALCA Positive_regulation of Gene_expression of IL8 1 0.72 0.92 3.52
4 INT180984 IRF6 Positive_regulation of Localization of IL8 7 0.11 2.13 3.47
5 INT149492 PNOC Negative_regulation of Gene_expression of CCL2 1 0.15 0.68 3.17
6 INT208572 Binding of IL8 and CXCR1 6 0.33 5.2 3.08
7 INT182635 Binding of CCR5 and CCL5 2 0.09 4.19 3
8 INT73821 CALCA Positive_regulation of Localization of IL8 1 0.25 2.37 2.91
9 INT318996 Binding of CCR3 and CCL5 1 0.07 3.39 2.9
10 INT319003 Binding of CCR1 and CCL5 1 0.08 3.38 2.89
11 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81
12 INT69030 IL18 Positive_regulation of IL12A 3 0.31 5.57 2.72
13 INT107322 Positive_regulation of TRPV1 Positive_regulation of Localization of IL8 3 0.13 1.64 2.5
14 INT149494 PNOC Negative_regulation of Gene_expression of CCL5 1 0.19 0.52 2.46
15 INT85252 Negative_regulation of Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.26
16 INT124121 IL6 Positive_regulation of CCL2 1 0.26 1.84 2.25
17 INT85251 Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.25
18 INT124120 IL6 Regulation of CCL2 1 0.15 1.8 2.22
19 INT128997 Cxcl1 Positive_regulation of Localization of Ccl2 1 0.72 1.54 2.16
20 INT81295 Ifng Positive_regulation of Gene_expression of Nos2 4 0.39 0.87 2.05
21 INT128996 Ccl2 Positive_regulation of Localization of Calca 1 0.68 1.43 2
22 INT91607 Binding of EDN1 and POMC 1 0.12 0 1.9
23 INT161224 Ccl2 Positive_regulation of Ccr2 1 0.52 2.09 1.88
24 INT201940 Binding of IL8 and CXCL10 2 0.28 2.46 1.86
25 INT267133 Binding of ICAM1 and VCAM1 25 0.32 25.43 1.83
26 INT136034 Edn1 Regulation of Trpv1 2 0.66 0.39 1.58
27 INT151849 IL10 Negative_regulation of Gene_expression of IL8 4 0.14 3.26 1.54
28 INT256360 Car2 Positive_regulation of Localization of Rela 1 0.14 0 1.51
29 INT260897 CRH Positive_regulation of Localization of IL8 1 0.24 0.09 1.51
30 INT293013 IL8 Positive_regulation of Positive_regulation of CA2 1 0.12 0.66 1.49
31 INT340300 Ea1 Positive_regulation of Gene_expression of Sirt1 1 0.08 1.68 1.49
32 INT176368 IL18 Positive_regulation of Gene_expression of IFNA1 1 0.16 2.53 1.35
33 INT160585 IL18 Positive_regulation of Gene_expression of OPRM1 1 0.09 0.54 1.35
34 INT95275 Binding of Edn1 and Ece1 1 0.32 2.09 1.3
35 INT95274 Regulation of Binding of Edn1 and Ece1 1 0.39 2.09 1.3
36 INT112961 NGF Positive_regulation of ICAM1 1 0.40 0.96 1.28
37 INT177232 ICAM1 Regulation of Gene_expression of Vcam1 1 0.03 5.52 1.28
38 INT181436 Binding of Ccl2 and Eae1 1 0.05 5.14 1.27
39 INT254210 Binding of Cxcr2 and Ccl2 1 0.08 2.39 1.25
40 INT151648 TLR4 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
41 INT151657 Vcam1 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
42 INT151658 F3 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
43 INT334129 Acsm3 Positive_regulation of Gene_expression of Icam1 1 0.22 2.89 1.22
44 INT62596 Binding of Edn1 and Nppa 1 0.27 1.77 1.22
45 INT200455 OPRK1 Positive_regulation of Gene_expression of CCL2 1 0.19 0.07 1.21
46 INT55162 Binding of NFKB1 and RELA 10 0.30 2.82 1.18
47 INT201067 Binding of Edn1 and Ednra 2 0.18 1.36 1.18
48 INT147447 ADCYAP1 Regulation of Localization of RELA 1 0.50 1.12 1.15
49 INT260810 Binding of CXCL10 and CCL2 1 0.10 1.37 1.12
50 INT83616 Binding of IL6 and IL8 5 0.09 5.8 1.11
51 INT71176 Binding of ICAM1 and ITGB2 4 0.21 4.93 1.07
52 INT139230 Icam1 Negative_regulation of Cmklr1 1 0.19 1.13 1.07
53 INT10238 Binding of EDN1 and Calca 1 0.00 1.07 1.06
54 INT139227 Icam1 Negative_regulation of Timp1 1 0.37 1.13 1.06
55 INT139225 Calca Negative_regulation of Icam1 1 0.44 1.13 1.06
56 INT139226 Icam1 Negative_regulation of Calca 1 0.44 1.12 1.05
57 INT181434 Binding of Ccr2 and Ccl2 1 0.27 6.06 1.04
58 INT133072 GATA3 Positive_regulation of Transcription of OPRM1 1 0.35 0 1.04
59 INT88875 Ifng Positive_regulation of Transcription of Nos2 1 0.02 0.27 1.03
60 INT101381 POMC Regulation of Localization of IL8 1 0.28 1.49 1.02
61 INT203178 IL18 Positive_regulation of Gene_expression of Lts1 1 0.01 1.98 1.02
62 INT88887 IRF6 Positive_regulation of Transcription of Nos2 1 0.21 0.27 1.02
63 INT88874 Ifng Regulation of Nos2 1 0.01 0.26 1.01
64 INT293008 IL8 Positive_regulation of Localization of CA2 1 0.11 0.71 1.01
65 INT88884 IRF6 Regulation of Nos2 1 0.12 0.26 1
66 INT88886 IRF6 Positive_regulation of Nos2 1 0.22 0.26 1
67 INT278946 IL6 Regulation of Gene_expression of IL8 1 0.20 1.9 1
68 INT88888 Regulation of IRF6 Positive_regulation of Nos2 1 0.20 0.26 1
69 INT103651 IL1B Positive_regulation of Gene_expression of IL8 6 0.78 1.23 0.98
70 INT167173 Binding of Ccl2 and Ccr2 2 0.30 1.15 0.98
71 INT311102 IL8 Positive_regulation of CXCR7 1 0.00 1.74 0.98
72 INT311143 IL8 Positive_regulation of Cxcr1 1 0.04 1.74 0.98
73 INT103133 TNF Positive_regulation of Gene_expression of IL8 2 0.48 1.26 0.96
74 INT278940 LEP Positive_regulation of Gene_expression of IL8 1 0.34 1.68 0.96
75 INT256357 Phosphorylation of Rela Positive_regulation of Localization of Ik 1 0.00 0.05 0.96
76 INT135585 CSF2 Regulation of CCL2 1 0.13 2.51 0.95
77 INT182190 Binding of IL8 and CXCR4 1 0.26 1.25 0.95
78 INT136033 Edn1 Positive_regulation of Trpv1 1 0.50 0.34 0.95
79 INT133071 STAT6 Positive_regulation of Gene_expression of GATA3 1 0.55 0 0.95
80 INT133050 TNF Positive_regulation of Gene_expression of ICAM1 3 0.67 1.91 0.94
81 INT77859 EDN1 Positive_regulation of MC1R 2 0.64 0.34 0.94
82 INT299988 IL6 Positive_regulation of Localization of IL8 1 0.05 0.81 0.94
83 INT182206 Binding of CXCR5 and IL8 1 0.30 1.25 0.94
84 INT182196 Binding of IL8 and CXCL13 1 0.27 1.24 0.93
85 INT129003 Ccl2 Positive_regulation of ANTXRL 1 0.00 0.68 0.92
86 INT289461 IRF6 Positive_regulation of ICAM1 1 0.08 0.61 0.91
87 INT250976 Binding of FMOD and IL8 1 0.08 1.26 0.91
88 INT221386 Tlr4 Positive_regulation of Gene_expression of IL8 6 0.14 3.53 0.9
89 INT108687 Nfkb1 Regulation of Positive_regulation of Nos2 1 0.50 1.28 0.88
90 INT62956 CXCR2 Positive_regulation of IL8 1 0.30 0 0.88
91 INT108686 Nfkb1 Regulation of Nos2 1 0.69 1.27 0.88
92 INT186672 IL8 Positive_regulation of Transcription of PTH 1 0.01 1.83 0.85
93 INT196578 Ephb1 Positive_regulation of Phosphorylation of Mapk9 1 0.13 0.5 0.85
94 INT196576 Trib3 Positive_regulation of Phosphorylation of Mapk9 1 0.02 0.5 0.85
95 INT146919 Tnf Positive_regulation of Gene_expression of Ccl2 1 0.16 1.44 0.84
96 INT302379 Crp Positive_regulation of Gene_expression of Ccl2 1 0.10 4.58 0.84
97 INT287494 CRP Positive_regulation of Gene_expression of CCL2 2 0.30 2.33 0.83
98 INT149561 Tgfb1 Positive_regulation of Gene_expression of CCL2 1 0.00 0 0.83
99 INT102931 Nos3 Positive_regulation of Nos2 1 0.43 1.63 0.83
100 INT340294 Ea1 Positive_regulation of Sirt1 1 0.06 0.53 0.83
101 INT149563 Tgfb1 Positive_regulation of CCL2 1 0.00 0 0.83
102 INT106859 EDN1 Positive_regulation of Transcription of MC1R 1 0.22 0 0.82
103 INT149557 Tgfb1 Positive_regulation of Gene_expression of Ccl5 1 0.00 0 0.82
104 INT87490 CALCA Positive_regulation of Gene_expression of CCL5 1 0.30 0.14 0.81
105 INT87494 CALCA Positive_regulation of IL8 1 0.48 0.15 0.81
106 INT88885 IRF6 Positive_regulation of Gene_expression of Nos2 1 0.21 0.1 0.81
107 INT88878 Negative_regulation of Nfkb1 Positive_regulation of Gene_expression of Nos2 1 0.06 0.1 0.81
108 INT87489 CALCA Positive_regulation of Gene_expression of CCL2 1 0.43 0.14 0.81
109 INT87492 CALCA Regulation of IL8 1 0.28 0.15 0.81
110 INT286346 IRF6 Positive_regulation of IL8 3 0.03 0.88 0.8
111 INT219911 Edn1 Regulation of Gene_expression of Trpv1 1 0.23 0.57 0.8
112 INT226371 IL18 Positive_regulation of IL4 4 0.05 2.49 0.79
113 INT239671 Binding of Ccl2 and Gtf3a 1 0.02 1.34 0.79
114 INT182814 Binding of ICAM1 and PECAM1 2 0.02 3.32 0.77
115 INT149493 PNOC Negative_regulation of CCL5 1 0.14 0.16 0.77
116 INT149495 PNOC Negative_regulation of CCL2 1 0.11 0.16 0.77
117 INT87493 Binding of CALCA and Positive_regulation of Gene_expression of IL8 1 0.52 0.18 0.76
118 INT128815 Mapk14 Regulation of Gene_expression of Nos2 1 0.21 0.46 0.74
119 INT258644 Binding of CCL2 and CCL5 1 0.36 1.6 0.74
120 INT258643 Positive_regulation of Binding of CCL2 and CCL5 1 0.49 1.61 0.74
121 INT128813 Mapk8 Regulation of Gene_expression of Nos2 1 0.23 0.46 0.74
122 INT228494 Binding of Ncoa5 and Rela 1 0.00 1.58 0.72
123 INT248244 Binding of IL8 and SDC2 1 0.02 1.57 0.72
124 INT64117 Binding of Edn1 and Ins1 1 0.06 0.85 0.71
125 INT222493 Edn1 Positive_regulation of Localization of Prl 1 0.10 0 0.71
126 INT153123 NFKBIA Negative_regulation of Phosphorylation of RELA 1 0.03 2.01 0.71
127 INT267630 Il1 Regulation of Gene_expression of IL8 1 0.00 0.44 0.71
128 INT120018 VEGFA Positive_regulation of CCL3 1 0.01 1 0.7
129 INT224580 Gene_expression of IL18 Positive_regulation of SERPINH1 1 0.00 1.34 0.7
130 INT120017 CCL2 Positive_regulation of CCL3 1 0.01 0.99 0.7
131 INT120020 VEGFA Positive_regulation of CCL2 1 0.00 1 0.7
132 INT120035 CCL2 Positive_regulation of Prap1 1 0.00 0.99 0.7
133 INT63557 Binding of Edn1 and Edn3 1 0.23 0.63 0.7
134 INT120037 IL8 Positive_regulation of Prap1 1 0.00 0.99 0.7
135 INT120019 IL8 Positive_regulation of CCL3 1 0.02 0.99 0.7
136 INT187522 ATIC Negative_regulation of Gene_expression of Nos2 1 0.02 1.46 0.7
137 INT278956 LEP Regulation of Gene_expression of IL8 1 0.30 1.11 0.69
138 INT130717 Binding of OPRM1 and Positive_regulation of Localization of CCL2 1 0.00 0.72 0.68
139 INT278827 Binding of EDN1 and EDNRB 3 0.17 2.7 0.67
140 INT194618 Il17a Positive_regulation of Gene_expression of IL8 2 0.01 1.94 0.67
141 INT299989 PRKCA Positive_regulation of Gene_expression of IL8 1 0.04 0.45 0.67
142 INT70998 IL1B Regulation of Gene_expression of Icam1 1 0.44 0.95 0.67
143 INT298728 Akt1 Positive_regulation of Rela 1 0.01 1.03 0.67
144 INT245299 Ccl5 Positive_regulation of Localization of IL8 1 0.11 2.87 0.66
145 INT334133 Acsm3 Positive_regulation of Icam1 1 0.23 1.61 0.66
146 INT220035 Nos1 Positive_regulation of Nos2 1 0.29 0.45 0.66
147 INT116441 IL1B Positive_regulation of Gene_expression of CCL2 2 0.04 0.62 0.65
148 INT313702 Binding of Edn1 and Fig4 1 0.16 0 0.65
149 INT153750 Binding of CCL2 and Crp 1 0.02 1.8 0.65
150 INT313698 Binding of Calca and Edn1 1 0.30 0 0.65
151 INT153751 Regulation of Binding of CCL2 and Crp 1 0.03 1.8 0.65
152 INT66603 TFF2 Positive_regulation of Gene_expression of ICAM1 1 0.02 0 0.64
153 INT281130 Ccl2 Regulation of Gene_expression of Ccr2 1 0.04 1.09 0.64
154 INT264329 Binding of IL-17 and Positive_regulation of Localization of Ccl2 1 0.13 1.65 0.64
155 INT281134 Ccl2 Positive_regulation of Gene_expression of Ccr2 1 0.08 1.09 0.64
156 INT292893 TNF Regulation of IL8 2 0.27 1.3 0.63
157 INT281122 Ccl2 Regulation of Ccr2 1 0.04 1.09 0.63
158 INT266489 Dcps Positive_regulation of Gene_expression of Nos2 1 0.06 3.43 0.63
159 INT66602 TFF2 Positive_regulation of Gene_expression of IL8 1 0.01 0 0.63
160 INT346141 ADM Positive_regulation of Gene_expression of ICAM1 1 0.19 1.75 0.63
161 INT66601 WDR87 Positive_regulation of Gene_expression of ICAM1 1 0.00 0 0.63
162 INT66604 SARDH Positive_regulation of Gene_expression of ICAM1 1 0.01 0 0.63
163 INT182266 EDN1 Positive_regulation of Gene_expression of MMP13 1 0.35 2.03 0.63
164 INT174860 VEGFA Positive_regulation of Localization of CCL2 1 0.21 1.68 0.63
165 INT219919 EDNRA Negative_regulation of Edn1 1 0.15 0.36 0.63
166 INT178097 Binding of EDN1 and EDNRA 7 0.21 5.97 0.62
167 INT252772 ELANE Regulation of Gene_expression of CCL2 1 0.05 2.16 0.62
168 INT176475 IL1B Positive_regulation of Gene_expression of ICAM1 1 0.02 0.56 0.62
169 INT252826 ROS1 Regulation of Gene_expression of CCL2 1 0.20 2.17 0.62
170 INT128812 Mapk8 Negative_regulation of Gene_expression of Nos2 1 0.19 0.37 0.61
171 INT128817 Ephb1 Negative_regulation of Gene_expression of Nos2 1 0.16 0.37 0.61
172 INT182815 Binding of CD63 and ICAM1 1 0.00 1.63 0.61
173 INT169287 EGF Positive_regulation of Localization of IL8 1 0.15 0.13 0.61
174 INT124831 Fbp1 Positive_regulation of Nos2 1 0.36 0.64 0.61
175 INT342989 IL8 Regulation of SFTPA1 1 0.02 0.38 0.6
176 INT272146 PTAFR Positive_regulation of Localization of IL8 3 0.38 0.28 0.59
177 INT178087 EDN1 Positive_regulation of MMP13 2 0.23 1.58 0.59
178 INT316831 CCL5 Positive_regulation of Gene_expression of MMP2 1 0.02 0.51 0.59
179 INT169299 CNR1 Positive_regulation of Localization of IL8 1 0.20 0.11 0.59
180 INT339072 Eae1 Positive_regulation of Gene_expression of Nos2 1 0.02 3.76 0.59
181 INT202038 MMP9 Positive_regulation of IL8 1 0.05 0.29 0.59
182 INT128810 Il1b Positive_regulation of Gene_expression of Nos2 1 0.04 0.31 0.59
183 INT176470 TNF Positive_regulation of Gene_expression of CCL2 1 0.15 0.62 0.58
184 INT130162 Pomc Positive_regulation of Gene_expression of Edn1 1 0.25 0 0.58
185 INT143426 Positive_regulation of B4GALNT1 Negative_regulation of Gene_expression of Nos2 1 0.00 0.83 0.58
186 INT277828 Negative_regulation of Binding of ICAM1 and ITGAL 2 0.22 1.27 0.57
187 INT151459 Olr1745 Negative_regulation of Gene_expression of Nos2 1 0.04 0.82 0.57
188 INT147201 Binding of CCL2 and Hsp70-2os 1 0.00 0.76 0.57
189 INT78588 Positive_regulation of Binding of Nfkb1 and Nos2 1 0.01 0.33 0.56
190 INT66600 TFF2 Regulation of Positive_regulation of ICAM1 1 0.01 0 0.56
191 INT176370 IL18BP Negative_regulation of IL18 1 0.15 0.76 0.56
192 INT81546 TNF Positive_regulation of Gene_expression of Nos2 1 0.04 0.54 0.56
193 INT78587 Binding of Nfkb1 and Nos2 1 0.01 0.33 0.55
194 INT176340 CHI3L1 Positive_regulation of Localization of CSF2 1 0.11 1.86 0.55
195 INT176343 CHI3L1 Positive_regulation of Localization of CSF1 1 0.23 1.86 0.55
196 INT133049 TNF Positive_regulation of ICAM1 4 0.47 2.49 0.54
197 INT62597 Binding of Edn1 and Vip 1 0.23 0.79 0.54
198 INT226360 IL18 Positive_regulation of Gene_expression of IL4 1 0.05 2.66 0.54
199 INT226348 IL18 Positive_regulation of Gene_expression of IL13 1 0.03 2.66 0.54
200 INT210934 Gene_expression of Tlr4 Negative_regulation of Ccl2 1 0.47 0.69 0.54

Single Events

The table below shows the top 100 pain related interactions that have been reported for cellular response to tumor necrosis factor. They are ordered first by their pain relevance and then by number of times they were reported in cellular response to tumor necrosis factor. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT10832 Gene_expression of IL8 1050 0.78 698.72 270
2 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08
3 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02
4 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87
5 INT12339 Localization of IL8 437 0.81 251.87 117.39
6 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62
7 INT82878 Gene_expression of Ccl2 201 0.78 164.95 101.35
8 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6
9 INT48406 Gene_expression of Icam1 277 0.78 238.28 81.71
10 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53
11 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34
12 INT102546 Gene_expression of Ccl2 197 0.78 192.8 67.41
13 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85
14 INT78899 Gene_expression of CCL5 155 0.77 84.02 55.09
15 INT48952 Negative_regulation of Nos2 204 0.59 101.73 53.15
16 INT49017 Negative_regulation of Gene_expression of Nos2 169 0.59 80.64 52.67
17 INT5781 Gene_expression of Edn1 190 0.78 99.1 46
18 INT81498 Positive_regulation of Gene_expression of CCL2 107 0.70 53.89 45.22
19 INT82883 Positive_regulation of Ccl2 105 0.69 84.96 42.27
20 INT48222 Positive_regulation of Localization of IL8 123 0.59 78.04 37.2
21 INT62827 Positive_regulation of ICAM1 184 0.70 180.95 36.28
22 INT51017 Positive_regulation of Icam1 113 0.70 81.16 35.55
23 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19
24 INT65698 Localization of CCL2 118 0.81 77.54 32.69
25 INT84170 Positive_regulation of Gene_expression of Ccl2 58 0.69 48.79 32.43
26 INT77652 Negative_regulation of Gene_expression of IL8 99 0.59 67.57 30.21
27 INT82882 Localization of Ccl2 61 0.80 41.96 28
28 INT69036 Gene_expression of IL18 99 0.77 77.92 25.95
29 INT61953 Transcription of Nos2 101 0.72 46.64 25.49
30 INT10836 Negative_regulation of IL8 95 0.59 52.59 24.71
31 INT10835 Regulation of IL8 79 0.49 53.04 24.14
32 INT6726 Positive_regulation of Edn1 118 0.70 65.96 24.07
33 INT70503 Regulation of Gene_expression of Nos2 71 0.62 44 24.01
34 INT48407 Positive_regulation of Gene_expression of Icam1 61 0.70 57.91 21.54
35 INT52106 Negative_regulation of Localization of IL8 57 0.52 22.81 20.8
36 INT63340 Positive_regulation of Gene_expression of ICAM1 109 0.70 90.82 20.61
37 INT78901 Localization of CCL5 67 0.78 40.79 20.59
38 INT8662 Positive_regulation of EDN1 144 0.70 125.34 19.59
39 INT138696 Positive_regulation of Ccl2 57 0.67 59.57 19.58
40 INT5048 Binding of Edn1 55 0.47 18.86 19.16
41 INT101188 Gene_expression of Rela 81 0.56 23.43 19.15
42 INT89594 Gene_expression of Ccl5 44 0.54 24.08 18.62
43 INT10833 Regulation of Gene_expression of IL8 68 0.62 38.74 18.46
44 INT87861 Gene_expression of Il18 33 0.78 30.44 18.42
45 INT66857 Regulation of CCL2 39 0.53 28.55 18.35
46 INT84171 Negative_regulation of Gene_expression of Ccl2 30 0.58 26.37 18.28
47 INT55880 Negative_regulation of Gene_expression of CCL2 49 0.59 22.37 18.09
48 INT71680 Gene_expression of CCL3 43 0.75 33.7 18.01
49 INT55878 Regulation of Gene_expression of CCL2 34 0.62 15.71 17.97
50 INT113602 Positive_regulation of Gene_expression of Ccl2 48 0.70 48.71 17.85
51 INT62826 Negative_regulation of Gene_expression of ICAM1 75 0.58 46.39 17.72
52 INT61949 Regulation of Nos2 74 0.58 34.08 16.7
53 INT10834 Binding of IL8 65 0.48 41.66 16.53
54 INT52107 Transcription of IL8 63 0.72 41.66 16.06
55 INT93482 Localization of Rela 56 0.78 24.52 14.82
56 INT9191 Localization of EDN1 94 0.81 57.01 14.78
57 INT8904 Positive_regulation of Gene_expression of EDN1 66 0.70 65.4 14.42
58 INT91544 Gene_expression of CHI3L1 60 0.75 77.72 13.9
59 INT5806 Regulation of Edn1 63 0.62 23.46 13.88
60 INT6365 Localization of Edn1 56 0.81 18.84 13.83
61 INT144646 Positive_regulation of Rela 53 0.67 27.78 13.2
62 INT21979 Negative_regulation of EDN1 52 0.58 24.65 12.55
63 INT96850 Negative_regulation of CCL2 42 0.59 24.89 12.55
64 INT65713 Localization of ICAM1 42 0.81 39.55 11.49
65 INT48956 Negative_regulation of Positive_regulation of Nos2 34 0.46 13.15 11.15
66 INT56448 Regulation of ICAM1 52 0.60 55.1 10.96
67 INT4240 Positive_regulation of CCL5 32 0.58 20.55 10.65
68 INT78895 Regulation of CCL5 30 0.46 20.45 10.18
69 INT56450 Negative_regulation of Gene_expression of Icam1 33 0.52 27.21 10.15
70 INT10184 Regulation of EDN1 44 0.62 23.78 10.06
71 INT83450 Positive_regulation of Localization of CCL2 28 0.70 22.14 9.83
72 INT106200 Binding of Ccl2 22 0.42 16.7 9.75
73 INT80549 Binding of ICAM1 53 0.47 42.76 9.72
74 INT70850 Positive_regulation of Transcription of Nos2 30 0.70 18.95 9.68
75 INT87863 Positive_regulation of IL18 40 0.69 34.08 9.53
76 INT63341 Negative_regulation of ICAM1 42 0.59 30.45 9.5
77 INT87495 Positive_regulation of Gene_expression of CCL5 26 0.69 13.85 9.46
78 INT135407 Negative_regulation of Ccl2 33 0.57 32.74 9.45
79 INT140224 Localization of Ccl2 32 0.72 26.91 9.39
80 INT138700 Negative_regulation of Gene_expression of Ccl2 27 0.57 24.1 9.08
81 INT63338 Regulation of Gene_expression of ICAM1 42 0.62 28.26 9.06
82 INT66213 Localization of RELA 63 0.78 14.71 8.77
83 INT10237 Binding of EDN1 40 0.48 16 8.48
84 INT72337 Positive_regulation of Positive_regulation of Nos2 37 0.65 17.02 8.11
85 INT62944 Regulation of Icam1 33 0.47 23.52 7.94
86 INT48404 Regulation of Gene_expression of Icam1 21 0.62 15.1 7.81
87 INT10899 Positive_regulation of Gene_expression of Edn1 32 0.70 24.88 7.65
88 INT94127 Positive_regulation of Il18 14 0.69 14 7.47
89 INT89589 Negative_regulation of Ccl5 9 0.40 4.62 7.39
90 INT10104 Negative_regulation of Edn1 43 0.59 15.63 7.2
91 INT82881 Regulation of Ccl2 19 0.57 15.29 7.19
92 INT81493 Transcription of CCL2 20 0.65 13.63 6.78
93 INT256345 Phosphorylation of Rela 21 0.75 9.51 6.56
94 INT91721 Binding of IL18 21 0.48 21.17 6.56
95 INT120895 Binding of CCL2 22 0.37 15.86 6.55
96 INT92504 Negative_regulation of Ccl2 17 0.43 8.98 6.29
97 INT91657 Negative_regulation of IL18 20 0.48 15.97 6.12
98 INT75832 Positive_regulation of Positive_regulation of IL8 30 0.70 20.77 6.05
99 INT74422 Regulation of Localization of IL8 21 0.62 10.19 5.99
100 INT92470 Negative_regulation of Gene_expression of CCL5 15 0.50 5.46 5.86
101 INT71727 Negative_regulation of Icam1 25 0.45 17.76 5.73
102 INT75833 Negative_regulation of Positive_regulation of IL8 15 0.53 6.69 5.59
103 INT83290 Regulation of Gene_expression of Ccl2 8 0.59 9.06 5.56
104 INT4613 Positive_regulation of Sirt1 32 0.67 18.19 5.53
105 INT113420 Positive_regulation of Gene_expression of IL18 22 0.69 19.96 5.53
106 INT65712 Positive_regulation of Localization of ICAM1 14 0.70 16.72 5.5
107 INT140223 Regulation of Ccl2 15 0.45 13.1 5.41
108 INT73608 Localization of Nos2 21 0.75 9.58 5.05
109 INT75831 Positive_regulation of Transcription of IL8 21 0.63 13.56 4.98
110 INT161220 Binding of Ccl2 17 0.46 17.63 4.94
111 INT82887 Positive_regulation of Ccl5 10 0.40 3.4 4.91
112 INT61950 Regulation of Positive_regulation of Nos2 17 0.43 9.01 4.87
113 INT103073 Positive_regulation of Positive_regulation of Ccl2 10 0.50 6.74 4.7
114 INT240934 Gene_expression of Sirt1 24 0.75 18.77 4.68
115 INT89590 Negative_regulation of Gene_expression of Ccl5 8 0.36 3.97 4.67
116 INT96851 Negative_regulation of Localization of CCL2 14 0.53 5.98 4.57
117 INT55171 Gene_expression of RELA 80 0.75 17.17 4.47
118 INT125884 Positive_regulation of CHI3L1 15 0.62 34.04 4.43
119 INT75440 Regulation of Binding of Edn1 4 0.38 1.41 4.33
120 INT4239 Negative_regulation of CCL5 15 0.40 10.92 4.26
121 INT89784 Regulation of Transcription of Nos2 14 0.42 8.39 4.24
122 INT93483 Negative_regulation of Localization of Rela 11 0.57 5.1 4.19
123 INT79234 Positive_regulation of CCL3 15 0.67 11.43 4.15
124 INT158377 Positive_regulation of Positive_regulation of Rela 6 0.49 3.08 4.11
125 INT28673 Gene_expression of APOB 51 0.73 34.02 3.95
126 INT68255 Regulation of Positive_regulation of IL8 12 0.41 5.71 3.91
127 INT118583 Positive_regulation of IRF1 10 0.68 3.75 3.91
128 INT35175 Localization of IL18 18 0.80 12.96 3.83
129 INT70996 Positive_regulation of Positive_regulation of Icam1 8 0.60 6.02 3.74
130 INT133550 Negative_regulation of Gene_expression of Rela 14 0.40 4.64 3.73
131 INT112340 Gene_expression of Cyp11a1 11 0.77 5.19 3.7
132 INT103281 Transcription of CCL5 10 0.67 5.95 3.7
133 INT89592 Localization of Ccl5 10 0.61 7.65 3.62
134 INT104480 Phosphorylation of Mapk9 8 0.80 6.59 3.62
135 INT31580 Negative_regulation of Cyp11a1 14 0.57 3.48 3.61
136 INT117518 Transcription of Ccl2 12 0.68 11.12 3.61
137 INT195527 Binding of Rela 17 0.25 4.42 3.56
138 INT148151 Regulation of Il18 7 0.28 5.4 3.5
139 INT73557 Positive_regulation of RELA 57 0.46 8.7 3.43
140 INT95272 Regulation of Gene_expression of Edn1 19 0.53 17.85 3.42
141 INT124123 Positive_regulation of Localization of CCL5 12 0.67 7 3.37
142 INT61952 Negative_regulation of Transcription of Nos2 17 0.54 5.1 3.34
143 INT126223 Binding of Nos2 17 0.37 6 3.22
144 INT181355 Regulation of Gene_expression of Ccl2 12 0.44 10.37 3.21
145 INT133557 Transcription of Rela 6 0.52 3.86 3.2
146 INT82879 Regulation of Ccl5 9 0.30 6.19 3.17
147 INT70994 Negative_regulation of Positive_regulation of Icam1 8 0.51 3.49 3.12
148 INT78898 Regulation of Gene_expression of CCL5 9 0.42 5.7 3.11
149 INT115617 Binding of Ccl5 5 0.33 0.58 3.11
150 INT66212 Negative_regulation of Localization of RELA 13 0.57 2.48 3.09
151 INT135409 Transcription of Ccl2 13 0.62 10.59 3.06
152 INT64386 Binding of Cyp11a1 13 0.46 5.09 3.01
153 INT176383 Negative_regulation of Binding of IL18 1 0.35 5.91 2.91
154 INT133080 Gene_expression of GATA3 15 0.61 5.64 2.89
155 INT15157 Gene_expression of INPP5K 30 0.67 15.49 2.85
156 INT139562 Transcription of IL18 10 0.68 6.14 2.73
157 INT194661 Binding of CCL5 9 0.46 6.07 2.73
158 INT153221 Positive_regulation of Rela 5 0.16 2.16 2.72
159 INT100014 Negative_regulation of Gene_expression of EDN1 17 0.42 7.85 2.71
160 INT74216 Binding of Icam1 16 0.48 10.11 2.69
161 INT115622 Positive_regulation of Binding of IL8 7 0.44 5.79 2.69
162 INT72757 Negative_regulation of Negative_regulation of Nos2 8 0.42 4.23 2.68
163 INT125885 Positive_regulation of Gene_expression of CHI3L1 8 0.49 10.8 2.64
164 INT67618 Positive_regulation of Inpp5k 3 0.45 0.77 2.64
165 INT222289 Localization of Il18 4 0.30 3.24 2.58
166 INT117519 Positive_regulation of Transcription of Ccl2 5 0.49 6.01 2.54
167 INT141195 Negative_regulation of Rela 14 0.29 8.61 2.44
168 INT79609 Positive_regulation of Negative_regulation of Nos2 5 0.49 3.6 2.43
169 INT159604 Gene_expression of IL18BP 3 0.49 4.56 2.42
170 INT162518 Positive_regulation of Localization of Rela 12 0.47 1.96 2.41
171 INT135470 Transcription of Icam1 10 0.63 12.04 2.41
172 INT138785 Gene_expression of Lcn2 9 0.56 9.88 2.41
173 INT71681 Positive_regulation of Gene_expression of CCL3 8 0.54 8.21 2.41
174 INT133567 Regulation of IL18 11 0.50 9.54 2.31
175 INT82880 Positive_regulation of Localization of Ccl2 4 0.49 2.65 2.31
176 INT72865 Localization of Icam1 12 0.68 8.18 2.24
177 INT55853 Positive_regulation of Positive_regulation of Edn1 11 0.61 6.5 2.21
178 INT148152 Binding of Il18 4 0.46 4.44 2.19
179 INT113906 Regulation of Positive_regulation of CCL2 4 0.27 3.2 2.17
180 INT77651 Negative_regulation of Transcription of IL8 8 0.43 4.48 2.16
181 INT221409 Regulation of Sirt1 8 0.58 5.53 2.1
182 INT128993 Negative_regulation of Localization of Ccl2 1 0.42 1.5 2.1
183 INT67190 Gene_expression of Muc2 24 0.78 18.8 2.08
184 INT49253 Regulation of Gene_expression of EDN1 11 0.61 3.92 2.07
185 INT94128 Positive_regulation of Gene_expression of Il18 6 0.50 3.64 2.06
186 INT154751 Positive_regulation of Positive_regulation of Ccl2 2 0.48 2.43 2.06
187 INT118305 Negative_regulation of Gene_expression of IL18 7 0.39 6.52 2.05
188 INT113907 Regulation of Localization of CCL2 5 0.62 2.46 2.05
189 INT115616 Positive_regulation of Binding of Ccl5 3 0.25 0.59 2.04
190 INT98888 Negative_regulation of Gene_expression of Il18 3 0.43 1.72 2.02
191 INT118884 Gene_expression of IRF1 5 0.66 2.71 2
192 INT123530 Phosphorylation of RELA 9 0.80 3.46 1.99
193 INT100490 Negative_regulation of Positive_regulation of CCL2 6 0.23 1.48 1.96
194 INT158022 Binding of CHI3L1 10 0.43 14.18 1.94
195 INT49259 Regulation of Localization of EDN1 8 0.61 6.29 1.92
196 INT118882 Positive_regulation of Gene_expression of IRF1 1 0.49 1.35 1.92
197 INT103061 Positive_regulation of Gene_expression of Ccl5 4 0.35 1.67 1.9
198 INT144649 Negative_regulation of Positive_regulation of Rela 11 0.26 8.27 1.87
199 INT40877 Positive_regulation of APOB 35 0.68 32.47 1.86
200 INT67980 Positive_regulation of Positive_regulation of CCL2 7 0.49 5.89 1.85
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