GO:0071359

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Name cellular response to dsRNA
Categary Process
Go Slim No
Go Link GO:0071359
Unique Molecular Interactions 107
Total Molecular Interactions 132
Total Single Events 1702
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cellular response to dsRNA. They are ordered first by their pain relevance and then by number of times they were reported for cellular response to dsRNA. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT102284 Binding of Grin1 and Grin2a 5 0.27 1.79 3.01
2 INT156799 Gria1 Regulation of Grm8 1 0.11 1.29 2.45
3 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
4 INT293200 Positive_regulation of Grin1 Positive_regulation of Phosphorylation of Grin2b 1 0.24 0.4 1.39
5 INT122267 Prkcg Positive_regulation of Grin2b 1 0.26 0.61 1.14
6 INT132683 Bdnf Positive_regulation of Phosphorylation of Grin2a 1 0.00 0.93 1.11
7 INT122268 Binding of Grin2b and Grm5 1 0.40 0.52 1.1
8 INT269189 Binding of Grin2a and Grin3a 2 0.25 1.05 1.09
9 INT269193 Prkcg Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
10 INT269192 Ephb1 Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
11 INT269198 Prkaca Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
12 INT353690 Binding of Grin2b and Ca2 1 0.14 1.17 1.01
13 INT338893 TNFSF14 Positive_regulation of Gene_expression of Gria1 1 0.07 0.59 0.94
14 INT122269 Src Negative_regulation of Positive_regulation of Grin2b 1 0.27 0.44 0.92
15 INT122266 Src Negative_regulation of Grin2b 1 0.27 0.43 0.91
16 INT127545 Gria1 Positive_regulation of Gene_expression of Gnptab 1 0.00 0.7 0.83
17 INT212290 Binding of Grin2a and Grin2b 2 0.20 1.36 0.82
18 INT214876 Ap3d1 Negative_regulation of Gria1 1 0.00 0.4 0.78
19 INT311525 Binding of Gria1 and Ltp 1 0.00 0.1 0.73
20 INT186160 Negative_regulation of Grin2b Negative_regulation of Grin1 1 0.37 0.5 0.72
21 INT190984 Binding of Scn2a1 and Gria1 1 0.03 0.08 0.71
22 INT51433 Gria1 Positive_regulation of Eif3g 1 0.03 0 0.7
23 INT249485 Trib3 Negative_regulation of Phosphorylation of Grin2b 1 0.02 0.64 0.68
24 INT162224 Grin1 Positive_regulation of Gene_expression of Gria1 1 0.27 0.07 0.66
25 INT250084 Negative_regulation of Grin2b Negative_regulation of Positive_regulation of Ltp 1 0.18 0.07 0.66
26 INT249489 Src Negative_regulation of Phosphorylation of Grin2b 1 0.20 0.63 0.66
27 INT250078 Negative_regulation of Grin2b Negative_regulation of Ltp 1 0.18 0.07 0.66
28 INT302441 Binding of GRIN1 and Grin2b 1 0.10 1.27 0.63
29 INT186159 Grin2d Negative_regulation of Grin2b 1 0.21 0.82 0.62
30 INT249484 Trib3 Positive_regulation of Phosphorylation of Grin2b 1 0.01 0.57 0.61
31 INT134532 Grin2a Regulation of Ngfr 1 0.02 0 0.57
32 INT134531 Gria1 Regulation of Ngfr 1 0.01 0 0.57
33 INT134530 Grin1 Regulation of Gria1 1 0.12 0 0.56
34 INT312751 Phosphorylation of Gria1 Positive_regulation of GRIA1 1 0.18 0.22 0.55
35 INT259184 Binding of Gria2 and Gria1 2 0.26 0.28 0.54
36 INT311521 Gnrhr Positive_regulation of Gene_expression of Gria1 1 0.00 0.54 0.54
37 INT311522 Gnrhr Positive_regulation of Transcription of Gria1 1 0.00 0.54 0.54
38 INT249497 Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 0.02 0.51 0.54
39 INT249479 Binding of Ephb1 and Grin2b 1 0.29 0.37 0.54
40 INT349130 Phosphorylation of Gria1 Positive_regulation of Shisa9 1 0.00 0.49 0.52
41 INT120852 PRL Positive_regulation of IRF1 1 0.44 0.99 0.51
42 INT259180 Pdpk1 Positive_regulation of Gene_expression of Gria1 1 0.02 0.4 0.49
43 INT250080 Grin2b Positive_regulation of Ltp 1 0.22 0.19 0.49
44 INT120854 IRF1 Positive_regulation of Localization of TNF 1 0.20 0.94 0.49
45 INT259181 Phosphorylation of Pdpk1 Positive_regulation of Gene_expression of Gria1 1 0.02 0.4 0.49
46 INT259183 Gria1 Positive_regulation of Phosphorylation of Gria2 1 0.30 0.39 0.49
47 INT250081 Grin2a Positive_regulation of Ltp 1 0.20 0.14 0.48
48 INT273110 Bdnf Regulation of Positive_regulation of Gria1 1 0.43 0 0.47
49 INT249486 Positive_regulation of Ephb1 Positive_regulation of Phosphorylation of Grin2b 1 0.33 0.4 0.46
50 INT127394 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Grin2a 1 0.01 0.71 0.45
51 INT127396 Negative_regulation of Mdk Negative_regulation of Gene_expression of Grin2a 1 0.00 0.71 0.45
52 INT86069 Positive_regulation of Gria1 Positive_regulation of Gene_expression of Fos 1 0.11 0.3 0.42
53 INT127543 Gria1 Positive_regulation of Gene_expression of Cryge 1 0.00 0.35 0.42
54 INT74713 Binding of Gria1 and Olr1868 1 0.00 0 0.42
55 INT127546 Gria1 Positive_regulation of Gene_expression of Kcnab3 1 0.02 0.35 0.42
56 INT105733 Grin2b Negative_regulation of Gene_expression of Grin2a 1 0.22 0.09 0.41
57 INT279620 Negative_regulation of Binding of Grin2a and Grin2b 1 0.18 0.99 0.4
58 INT250076 Grin2a Regulation of Positive_regulation of Ltp 1 0.10 0.06 0.35
59 INT249492 Trib3 Regulation of Phosphorylation of Grin2b 1 0.01 0.23 0.35
60 INT236006 HTR1A Regulation of Grin2b 1 0.00 0 0.33
61 INT165580 Binding of Akt1 and Grin2b 1 0.02 0.2 0.32
62 INT250079 Grin2b Regulation of Ltp 1 0.18 0.31 0.29
63 INT212289 Vsnl1 Negative_regulation of Grin2a 1 0.04 0.38 0.28
64 INT103482 RARB Positive_regulation of Gene_expression of Gria1 1 0.00 0 0.27
65 INT249493 Binding of Grin2b and Src 1 0.17 0.15 0.26
66 INT103483 BDNF Positive_regulation of Gene_expression of Gria1 1 0.03 0 0.26
67 INT51432 Gria1 Positive_regulation of Trib3 1 0.04 0 0.25
68 INT120853 PRL Positive_regulation of Positive_regulation of IRF1 1 0.41 0.49 0.25
69 INT273109 Bdnf Positive_regulation of Gene_expression of Gria1 1 0.66 0.07 0.24
70 INT250075 Binding of Hpcal4 and Negative_regulation of Gene_expression of Grin2a 1 0.03 0 0.24
71 INT311527 Binding of Grin2a and Gria1 1 0.01 0 0.21
72 INT250074 Grin2b Positive_regulation of Gene_expression of Hpcal4 1 0.04 0.3 0.2
73 INT343837 TICAM1 Positive_regulation of IRF3 1 0.03 0.19 0.19
74 INT343854 TIRAP Positive_regulation of IRF3 1 0.06 0.19 0.19
75 INT343863 Binding of IRF1 and IRF3 1 0.03 0.12 0.17
76 INT273097 Binding of Bdnf and Gria1 1 0.39 0.17 0.16
77 INT311526 Gria1 Regulation of Gene_expression of Grin2a 1 0.01 0.32 0.15
78 INT249495 Binding of Grin2b and Efnb2 1 0.02 0.05 0.11
79 INT273108 Gria1 Regulation of Positive_regulation of Gria2 1 0.04 0.09 0.1
80 INT273104 Mtor Negative_regulation of Gene_expression of Gria1 1 0.46 0.15 0.08
81 INT273115 Bdnf Negative_regulation of Gene_expression of Gria1 1 0.47 0.15 0.08
82 INT218829 Ppp1cc Regulation of Phosphorylation of Gria1 1 0.20 0.63 0.07
83 INT346752 Binding of Dlg1 and Gria1 1 0.02 0 0.06
84 INT218830 Camk2a Regulation of Phosphorylation of Gria1 1 0.36 0.63 0.06
85 INT329045 Binding of Unc93b1 and Tlr3 1 0.03 0.7 0.05
86 INT346457 IRF3 Positive_regulation of IFNA1 1 0.03 0.56 0.05
87 INT250073 Grin2a Regulation of Grin2b 1 0.39 0.9 0.05
88 INT333559 TBK1 Regulation of Phosphorylation of IRF3 1 0.17 0.35 0.04
89 INT333633 Thse Positive_regulation of Transcription of IRF3 1 0.00 1.13 0.03
90 INT273102 Bdnf Regulation of Gria1 1 0.30 0.08 0.03
91 INT273095 Rbm14 Regulation of Gria1 1 0.00 0.07 0.03
92 INT273105 Mtor Regulation of Gria1 1 0.29 0.07 0.03
93 INT191182 Binding of IRF1 and PRPF31 1 0.06 0.09 0.03
94 INT333639 Tlr4 Positive_regulation of IRF3 1 0.31 0 0
95 INT313271 Binding of GRIN1 and GRIN2B 1 0.24 0.06 0
96 INT333565 TRAM1 Regulation of Phosphorylation of IRF3 1 0.17 0.59 0
97 INT169858 Grin1 Regulation of Gene_expression of Grin2b 1 0.42 0 0
98 INT333563 PRKCA Positive_regulation of Gene_expression of IRF3 1 0.05 0.06 0
99 INT333630 Tlr4 Regulation of Phosphorylation of IRF3 1 0.39 0.59 0
100 INT333637 Smpd1 Positive_regulation of IRF3 1 0.09 0.62 0
101 INT169856 Grin1 Positive_regulation of Grin2b 1 0.46 0 0
102 INT333638 Positive_regulation of Tlr4 Positive_regulation of Localization of IRF3 1 0.29 0.07 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cellular response to dsRNA. They are ordered first by their pain relevance and then by number of times they were reported in cellular response to dsRNA. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT104000 Phosphorylation of Grin2b 73 0.82 48.34 93.48
2 INT29708 Gene_expression of Gria1 177 0.78 56.36 77.37
3 INT79506 Gene_expression of Grin2b 122 0.78 43.71 73.42
4 INT8071 Positive_regulation of Gria1 102 0.70 26.61 53.37
5 INT51627 Gene_expression of Grin2a 82 0.76 25.09 47.6
6 INT82054 Positive_regulation of Grin2b 56 0.70 17.45 37.14
7 INT103998 Positive_regulation of Phosphorylation of Grin2b 33 0.69 19.08 36.08
8 INT114173 Phosphorylation of Gria1 27 0.82 33.73 31.24
9 INT49001 Regulation of Gria1 51 0.56 18.28 31.22
10 INT93033 Negative_regulation of Grin2b 48 0.58 20.94 28.54
11 INT49623 Negative_regulation of Gria1 39 0.59 12.4 21.59
12 INT102281 Positive_regulation of Gene_expression of Grin2b 27 0.70 10.38 20.84
13 INT90612 Positive_regulation of Grin2a 33 0.65 15.11 18.84
14 INT29709 Positive_regulation of Gene_expression of Gria1 36 0.69 9.43 17.83
15 INT93037 Regulation of Grin2b 26 0.57 11.9 16.92
16 INT114172 Positive_regulation of Phosphorylation of Gria1 8 0.63 15.73 14.99
17 INT61864 Regulation of Gene_expression of Gria1 24 0.62 13.27 14.3
18 INT49538 Binding of Gria1 22 0.47 2.66 13.35
19 INT103996 Negative_regulation of Phosphorylation of Grin2b 11 0.58 7.81 12.85
20 INT103997 Phosphorylation of Grin2a 17 0.64 10.75 12.67
21 INT122117 Negative_regulation of Gene_expression of Grin2b 20 0.59 11.3 12.55
22 INT51625 Regulation of Gene_expression of Grin2a 12 0.60 3.28 11.6
23 INT51626 Transcription of Grin2a 16 0.68 1.65 10.5
24 INT93036 Negative_regulation of Grin2a 23 0.50 7.1 10.32
25 INT8072 Localization of Gria1 17 0.75 2.62 10.04
26 INT80006 Regulation of Gene_expression of Grin2b 8 0.57 3.75 9.62
27 INT95342 Gene_expression of GRIN2B 21 0.75 4.99 9.32
28 INT78769 Regulation of Grin2a 16 0.58 5.22 9.28
29 INT57023 Negative_regulation of Gene_expression of Gria1 20 0.58 6.92 7.17
30 INT120298 Negative_regulation of Phosphorylation of Gria1 6 0.57 8.99 6.68
31 INT100926 Positive_regulation of Gene_expression of Grin2a 11 0.63 3.24 6.41
32 INT100658 Negative_regulation of Positive_regulation of Grin2b 7 0.41 1.39 6.17
33 INT74593 Transcription of Grin2b 10 0.66 1.21 5.98
34 INT94927 Transcription of Gria1 12 0.69 3.14 5.94
35 INT67693 Binding of Grin2a 9 0.38 1.74 5.68
36 INT127353 Regulation of Phosphorylation of Grin2b 5 0.45 1.6 5.29
37 INT92541 Localization of Grin2b 11 0.75 2.85 5.14
38 INT79505 Binding of Grin2b 9 0.36 1.43 4.61
39 INT92902 Negative_regulation of Positive_regulation of Gria1 6 0.57 1.06 4.1
40 INT103999 Positive_regulation of Phosphorylation of Grin2a 5 0.38 3.12 3.94
41 INT118583 Positive_regulation of IRF1 10 0.68 3.75 3.91
42 INT84564 Regulation of Positive_regulation of Gria1 2 0.33 1.86 3.3
43 INT51427 Positive_regulation of Positive_regulation of Gria1 11 0.45 1.33 3.28
44 INT90611 Positive_regulation of Positive_regulation of Grin2a 4 0.63 1.89 3
45 INT131973 Positive_regulation of Transcription of Gria1 3 0.49 0.35 2.62
46 INT105730 Localization of Grin2a 7 0.67 0.64 2.56
47 INT101055 Regulation of GRIN2B 4 0.61 1.39 2.5
48 INT118884 Gene_expression of IRF1 5 0.66 2.71 2
49 INT151942 Regulation of Negative_regulation of Grin2b 2 0.41 0.41 1.92
50 INT74595 Regulation of Transcription of Grin2a 2 0.42 0.66 1.92
51 INT118882 Positive_regulation of Gene_expression of IRF1 1 0.49 1.35 1.92
52 INT103624 Negative_regulation of Gene_expression of Grin2a 5 0.56 1.58 1.9
53 INT151174 Negative_regulation of Transcription of Grin2a 3 0.40 0 1.8
54 INT74594 Regulation of Transcription of Grin2b 1 0.42 0.17 1.8
55 INT130440 Phosphorylation of GRIN2B 2 0.79 2.93 1.79
56 INT312743 Regulation of Phosphorylation of Gria1 2 0.51 2.01 1.5
57 INT107379 Localization of GRIN2B 2 0.73 0.86 1.48
58 INT65179 Regulation of Regulation of Gria1 2 0.07 0.37 1.39
59 INT105729 Negative_regulation of Localization of Grin2a 3 0.38 0.08 1.29
60 INT249527 Positive_regulation of Positive_regulation of Grin2b 2 0.37 1.12 1.22
61 INT95347 Negative_regulation of GRIN2B 1 0.57 0 1.19
62 INT288489 Transcription of Tlr3 1 0.51 3.85 1.05
63 INT288483 Gene_expression of Tlr3 8 0.72 4.51 0.97
64 INT101056 Positive_regulation of GRIN2B 1 0.23 0.32 0.9
65 INT186168 Negative_regulation of Negative_regulation of Grin2b 2 0.35 0.54 0.85
66 INT165578 Regulation of Positive_regulation of Grin2b 3 0.41 1.07 0.74
67 INT114524 Binding of GRIN2B 3 0.36 0.44 0.74
68 INT139895 Positive_regulation of Gene_expression of GRIN2B 2 0.49 0.9 0.65
69 INT122116 Negative_regulation of Transcription of Grin2b 1 0.43 0.34 0.62
70 INT288485 Regulation of Transcription of Tlr3 1 0.20 0.85 0.61
71 INT200893 Negative_regulation of Transcription of Gria1 2 0.08 0.6 0.58
72 INT259171 Protein_catabolism of Gria1 1 0.76 0.48 0.58
73 INT271625 Protein_catabolism of Grin2b 1 0.38 0.26 0.57
74 INT156379 Regulation of Binding of Grin2a 1 0.36 0.17 0.52
75 INT156378 Regulation of Binding of Grin2b 1 0.28 0.17 0.52
76 INT163895 Positive_regulation of Phosphorylation of GRIN2B 1 0.09 0.99 0.48
77 INT271628 Negative_regulation of Regulation of Grin2a 2 0.28 1.05 0.47
78 INT271632 Negative_regulation of Regulation of Grin2b 2 0.28 1.06 0.47
79 INT250065 Positive_regulation of Localization of Grin2b 1 0.45 0 0.47
80 INT250060 Positive_regulation of Localization of Grin2a 1 0.42 0 0.47
81 INT271627 Regulation of Positive_regulation of Grin2a 1 0.30 0.23 0.4
82 INT271630 Negative_regulation of Localization of Grin2b 1 0.25 0 0.37
83 INT250062 Positive_regulation of Transcription of Grin2b 1 0.39 0.47 0.34
84 INT249529 Regulation of Phosphorylation of Grin2a 1 0.21 0.16 0.34
85 INT163897 Negative_regulation of Phosphorylation of GRIN2B 1 0.08 0.39 0.28
86 INT271629 Positive_regulation of Protein_catabolism of Grin2b 1 0.27 0.13 0.28
87 INT212295 Regulation of Negative_regulation of Grin2a 1 0.39 0.28 0.24
88 INT316938 Negative_regulation of Regulation of Gria1 1 0.32 0.23 0.24
89 INT108279 Positive_regulation of Binding of Grin2a 1 0.41 0 0.23
90 INT200897 Negative_regulation of Localization of Gria1 1 0.07 0 0.22
91 INT333601 Phosphorylation of IRF3 6 0.73 2.09 0.19
92 INT288491 Positive_regulation of Transcription of Tlr3 1 0.37 1.85 0.19
93 INT343899 Localization of IRF1 1 0.23 0.12 0.17
94 INT333604 Localization of IRF3 1 0.71 2.75 0.12
95 INT333625 Positive_regulation of IRF3 7 0.61 3.49 0.09
96 INT329066 Positive_regulation of Gene_expression of Tlr3 1 0.43 1.12 0.08
97 INT228376 Binding of Tlr3 2 0.45 2.2 0.07
98 INT333620 Transcription of IRF3 1 0.63 1.12 0.06
99 INT333598 Gene_expression of IRF3 1 0.60 0.58 0.05
100 INT333591 Negative_regulation of Gene_expression of IRF3 1 0.38 0.53 0.05
101 INT333607 Positive_regulation of Localization of IRF3 1 0.61 0.4 0.04
102 INT333618 Positive_regulation of Phosphorylation of IRF3 1 0.41 0.24 0.04
103 INT329051 Positive_regulation of Tlr3 1 0.65 0.33 0.04
104 INT333605 Regulation of Transcription of IRF3 1 0.40 0 0.03
105 INT333608 Negative_regulation of IRF3 1 0.38 1.92 0.03
106 INT333597 Regulation of Positive_regulation of IRF3 1 0.54 0.35 0.03
107 INT333615 Regulation of Gene_expression of IRF3 1 0.40 0 0
108 INT333624 Regulation of Phosphorylation of IRF3 1 0.40 0.59 0
109 INT280549 Regulation of Gene_expression of IRF1 1 0.20 0.81 0
110 INT333616 Regulation of IRF3 1 0.24 1.14 0
111 INT333623 Binding of IRF3 1 0.32 0 0
112 INT333603 Negative_regulation of Localization of IRF3 1 0.52 0 0
113 INT155518 Negative_regulation of Phosphorylation of Grin2a 1 0.31 0.05 0
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